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Results for ECM23

Z-value: 0.72

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Transcription factors associated with ECM23

Gene Symbol Gene ID Gene Info
ECM23
S000005942 Non-essential protein of unconfirmed function

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ECM23YPL021W-0.847.6e-08Click!

Activity profile of ECM23 motif

Sorted Z-values of ECM23 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
YFR055W 9.78
IRC7
Putative cystathionine beta-lyase; involved in copper ion homeostasis and sulfur metabolism; null mutant displays increased levels of spontaneous Rad52p foci; expression induced by nitrogen limitation in a GLN3, GAT1-dependent manner
YFR056C 8.88 Dubious open reading frame unlikely to encode a protein based on available experimental and comparative sequence data; partially overlaps the uncharacterized gene YFR055W
YJR094W-A 6.89
RPL43B
Protein component of the large (60S) ribosomal subunit, identical to Rpl43Ap and has similarity to rat L37a ribosomal protein
YOR315W 6.60
SFG1
Nuclear protein, putative transcription factor required for growth of superficial pseudohyphae (which do not invade the agar substrate) but not for invasive pseudohyphal growth; may act together with Phd1p; potential Cdc28p substrate
YLR413W 5.55 Putative protein of unknown function; YLR413W is not an essential gene
YGR108W 5.01
CLB1
B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the transition from G2 to M phase; accumulates during G2 and M, then targeted via a destruction box motif for ubiquitin-mediated degradation by the proteasome
YIR021W 4.49
MRS1
Protein required for the splicing of two mitochondrial group I introns (BI3 in COB and AI5beta in COX1); forms a splicing complex, containing four subunits of Mrs1p and two subunits of the BI3-encoded maturase, that binds to the BI3 RNA
YPR119W 4.26
CLB2
B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the transition from G2 to M phase; accumulates during G2 and M, then targeted via a destruction box motif for ubiquitin-mediated degradation by the proteasome
YKL218C 4.00
SRY1
3-hydroxyaspartate dehydratase, deaminates L-threo-3-hydroxyaspartate to form oxaloacetate and ammonia; required for survival in the presence of hydroxyaspartate
YGL179C 3.89
TOS3
Protein kinase, related to and functionally redundant with Elm1p and Sak1p for the phosphorylation and activation of Snf1p; functionally orthologous to LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome
YHR094C 3.70
HXT1
Low-affinity glucose transporter of the major facilitator superfamily, expression is induced by Hxk2p in the presence of glucose and repressed by Rgt1p when glucose is limiting
YKL164C 3.61
PIR1
O-glycosylated protein required for cell wall stability; attached to the cell wall via beta-1,3-glucan; mediates mitochondrial translocation of Apn1p; expression regulated by the cell integrity pathway and by Swi5p during the cell cycle
YKR038C 3.46
KAE1
Putative glycoprotease proposed to be in transcription as a component of the EKC protein complex with Bud32p, Cgi121p, Pcc1p, and Gon7p; also identified as a component of the KEOPS protein complex
YIL118W 3.42
RHO3
Non-essential small GTPase of the Rho/Rac subfamily of Ras-like proteins involved in the establishment of cell polarity; GTPase activity positively regulated by the GTPase activating protein (GAP) Rgd1p
YKR013W 3.33
PRY2
Protein of unknown function, has similarity to Pry1p and Pry3p and to the plant PR-1 class of pathogen related proteins
YNL178W 3.28
RPS3
Protein component of the small (40S) ribosomal subunit, has apurinic/apyrimidinic (AP) endonuclease activity; essential for viability; has similarity to E. coli S3 and rat S3 ribosomal proteins
YDR098C 3.28
GRX3
Hydroperoxide and superoxide-radical responsive glutathione-dependent oxidoreductase; monothiol glutaredoxin subfamily member along with Grx4p and Grx5p; protects cells from oxidative damage
YOR008C-A 3.18 Putative protein of unknown function, includes a potential transmembrane domain; deletion results in slightly lengthened telomeres
YLR150W 3.07
STM1
Protein that binds G4 quadruplex and purine motif triplex nucleic acid; acts with Cdc13p to maintain telomere structure; interacts with ribosomes and subtelomeric Y' DNA; multicopy suppressor of tom1 and pop2 mutations
YGR251W 3.03 Putative protein of unknown function; deletion mutant has defects in pre-rRNA processing; green fluorescent protein (GFP)-fusion protein localizes to both the nucleus and the nucleolus; YGR251W is an essential gene
YLR388W 2.88
RPS29A
Protein component of the small (40S) ribosomal subunit; nearly identical to Rps29Bp and has similarity to rat S29 and E. coli S14 ribosomal proteins
YDR033W 2.83
MRH1
Protein that localizes primarily to the plasma membrane, also found at the nuclear envelope; the authentic, non-tagged protein is detected in mitochondria in a phosphorylated state; has similarity to Hsp30p and Yro2p
YKR012C 2.80 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene PRY2
YOR028C 2.78
CIN5
Basic leucine zipper transcriptional factor of the yAP-1 family that mediates pleiotropic drug resistance and salt tolerance; localizes constitutively to the nucleus
YML127W 2.75
RSC9
Component of the RSC chromatin remodeling complex; DNA-binding protein involved in the synthesis of rRNA and in transcriptional repression and activation of genes regulated by the Target of Rapamycin (TOR) pathway
YCR018C 2.74
SRD1
Protein involved in the processing of pre-rRNA to mature rRNA; contains a C2/C2 zinc finger motif; srd1 mutation suppresses defects caused by the rrp1-1 mutation
YDL047W 2.74
SIT4
Type 2A-related serine-threonine phosphatase that functions in the G1/S transition of the mitotic cycle; cytoplasmic and nuclear protein that modulates functions mediated by Pkc1p including cell wall and actin cytoskeleton organization
YLL045C 2.69
RPL8B
Ribosomal protein L4 of the large (60S) ribosomal subunit, nearly identical to Rpl8Ap and has similarity to rat L7a ribosomal protein; mutation results in decreased amounts of free 60S subunits
YOR029W 2.67 Dubious open reading frame unlikely to encode a functional protein; based on available experimental and comparative sequence data
YNL066W 2.63
SUN4
Cell wall protein related to glucanases, possibly involved in cell wall septation; member of the SUN family
YNR001W-A 2.62 Dubious open reading frame unlikely to encode a functional protein; identified by homology
YOR313C 2.53
SPS4
Protein whose expression is induced during sporulation; not required for sporulation; heterologous expression in E. coli induces the SOS response that senses DNA damage
YOR342C 2.51 Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and the nucleus
YNR013C 2.51
PHO91
Low-affinity phosphate transporter of the vacuolar membrane; deletion of pho84, pho87, pho89, pho90, and pho91 causes synthetic lethality; transcription independent of Pi and Pho4p activity; overexpression results in vigorous growth
YOR314W 2.48 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
YLR264W 2.40
RPS28B
Protein component of the small (40S) ribosomal subunit; nearly identical to Rps28Ap and has similarity to rat S28 ribosomal protein
YLR287C 2.23 Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YLR287C is not an essential gene
YPL108W 2.20 Cytoplasmic protein of unknown function; non-essential gene that is induced in a GDH1 deleted strain with altered redox metabolism; GFP-fusion protein is induced in response to the DNA-damaging agent MMS
YFR054C 2.20 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YJL011C 2.18
RPC17
RNA polymerase III subunit C17; physically interacts with C31, C11, and TFIIIB70; may be involved in the recruitment of pol III by the preinitiation complex
YNL301C 2.17
RPL18B
Protein component of the large (60S) ribosomal subunit, identical to Rpl18Ap and has similarity to rat L18 ribosomal protein
YFL015W-A 2.14 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YFL015C 2.08 Dubious open reading frame unlikely to encode a protein; partially overlaps dubious ORF YFL015W-A; YFL015C is not an essential gene
YJR145C 2.07
RPS4A
Protein component of the small (40S) ribosomal subunit; mutation affects 20S pre-rRNA processing; identical to Rps4Bp and has similarity to rat S4 ribosomal protein
YMR049C 2.04
ERB1
Protein required for maturation of the 25S and 5.8S ribosomal RNAs; constituent of 66S pre-ribosomal particles; homologous to mammalian Bop1
YJL177W 1.99
RPL17B
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl17Ap and has similarity to E. coli L22 and rat L17 ribosomal proteins
YER011W 1.98
TIR1
Cell wall mannoprotein of the Srp1p/Tip1p family of serine-alanine-rich proteins; expression is downregulated at acidic pH and induced by cold shock and anaerobiosis; abundance is increased in cells cultured without shaking
YLR314C 1.97
CDC3
Component of the septin ring of the mother-bud neck that is required for cytokinesis; septins recruit proteins to the neck and can act as a barrier to diffusion at the membrane, and they comprise the 10nm filaments seen with EM
YGR060W 1.97
ERG25
C-4 methyl sterol oxidase, catalyzes the first of three steps required to remove two C-4 methyl groups from an intermediate in ergosterol biosynthesis; mutants accumulate the sterol intermediate 4,4-dimethylzymosterol
YDL085C-A 1.96 Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus
YPL245W 1.93 Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to both the nucleus and the cytoplasm
YJL107C 1.92 Putative protein of unknown function; expression is induced by activation of the HOG1 mitogen-activated signaling pathway and this induction is Hog1p/Pbs2p dependent; YJL107C and adjacent ORF, YJL108C are merged in related fungi
YBR078W 1.91
ECM33
GPI-anchored protein of unknown function, has a possible role in apical bud growth; GPI-anchoring on the plasma membrane crucial to function; phosphorylated in mitochondria; similar to Sps2p and Pst1p
YGR280C 1.89
PXR1
Essential protein involved in rRNA and snoRNA maturation; competes with TLC1 RNA for binding to Est2p, suggesting a role in negative regulation of telomerase; human homolog inhibits telomerase; contains a G-patch RNA interacting domain
YDL075W 1.86
RPL31A
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl31Bp and has similarity to rat L31 ribosomal protein; associates with the karyopherin Sxm1p
YDR385W 1.86
EFT2
Elongation factor 2 (EF-2), also encoded by EFT1; catalyzes ribosomal translocation during protein synthesis; contains diphthamide, the unique posttranslationally modified histidine residue specifically ADP-ribosylated by diphtheria toxin
YHR140W 1.86 Putative integral membrane protein of unknown function
YJL115W 1.85
ASF1
Nucleosome assembly factor, involved in chromatin assembly and disassembly, anti-silencing protein that causes derepression of silent loci when overexpressed; plays a role in regulating Ty1 transposition
YHR208W 1.80
BAT1
Mitochondrial branched-chain amino acid aminotransferase, homolog of murine ECA39; highly expressed during logarithmic phase and repressed during stationary phase
YMR202W 1.79
ERG2
C-8 sterol isomerase, catalyzes the isomerization of the delta-8 double bond to the delta-7 position at an intermediate step in ergosterol biosynthesis
YER137C 1.77 Putative protein of unknown function
YNR054C 1.76
ESF2
Essential nucleolar protein involved in pre-18S rRNA processing; binds to RNA and stimulates ATPase activity of Dbp8; involved in assembly of the small subunit (SSU) processome
YGL120C 1.72
PRP43
RNA helicase in the DEAH-box family, functions in both RNA polymerase I and polymerase II transcript metabolism, involved in release of the lariat-intron from the spliceosome
YML075C 1.69
HMG1
One of two isozymes of HMG-CoA reductase that catalyzes the conversion of HMG-CoA to mevalonate, which is a rate-limiting step in sterol biosynthesis; localizes to the nuclear envelope; overproduction induces the formation of karmellae
YLR325C 1.68
RPL38
Protein component of the large (60S) ribosomal subunit, has similarity to rat L38 ribosomal protein
YOL155C 1.66
HPF1
Haze-protective mannoprotein that reduces the particle size of aggregated proteins in white wines
YNL111C 1.65
CYB5
Cytochrome b5, involved in the sterol and lipid biosynthesis pathways; acts as an electron donor to support sterol C5-6 desaturation
YGR249W 1.64
MGA1
Protein similar to heat shock transcription factor; multicopy suppressor of pseudohyphal growth defects of ammonium permease mutants
YPR010C 1.64
RPA135
RNA polymerase I subunit A135
YDL241W 1.64 Putative protein of unknown function; YDL241W is not an essential gene
YGR214W 1.63
RPS0A
Protein component of the small (40S) ribosomal subunit, nearly identical to Rps0Bp; required for maturation of 18S rRNA along with Rps0Bp; deletion of either RPS0 gene reduces growth rate, deletion of both genes is lethal
YML026C 1.61
RPS18B
Protein component of the small (40S) ribosomal subunit; nearly identical to Rps18Ap and has similarity to E. coli S13 and rat S18 ribosomal proteins
YIL056W 1.60
VHR1
Transcriptional activator, required for the vitamin H-responsive element (VHRE) mediated induction of VHT1 (Vitamin H transporter) and BIO5 (biotin biosynthesis intermediate transporter) in response to low biotin concentrations
YOR030W 1.60
DFG16
Probable multiple transmembrane protein, involved in diploid invasive and pseudohyphal growth upon nitrogen starvation; required for accumulation of processed Rim101p
YNL112W 1.60
DBP2
Essential ATP-dependent RNA helicase of the DEAD-box protein family, involved in nonsense-mediated mRNA decay and rRNA processing
YDL134C 1.60
PPH21
Catalytic subunit of protein phosphatase 2A, functionally redundant with Pph22p; methylated at C terminus; forms alternate complexes with several regulatory subunits; involved in signal transduction and regulation of mitosis
YIL011W 1.57
TIR3
Cell wall mannoprotein of the Srp1p/Tip1p family of serine-alanine-rich proteins; expressed under anaerobic conditions and required for anaerobic growth
YDL055C 1.56
PSA1
GDP-mannose pyrophosphorylase (mannose-1-phosphate guanyltransferase), synthesizes GDP-mannose from GTP and mannose-1-phosphate in cell wall biosynthesis; required for normal cell wall structure
YGR208W 1.55
SER2
Phosphoserine phosphatase of the phosphoglycerate pathway, involved in serine and glycine biosynthesis, expression is regulated by the available nitrogen source
YGR148C 1.55
RPL24B
Ribosomal protein L30 of the large (60S) ribosomal subunit, nearly identical to Rpl24Ap and has similarity to rat L24 ribosomal protein; not essential for translation but may be required for normal translation rate
YKL009W 1.55
MRT4
Protein involved in mRNA turnover and ribosome assembly, localizes to the nucleolus
YGR040W 1.55
KSS1
Mitogen-activated protein kinase (MAPK) involved in signal transduction pathways that control filamentous growth and pheromone response; the KSS1 gene is nonfunctional in S288C strains and functional in W303 strains
YDL048C 1.54
STP4
Protein containing a Kruppel-type zinc-finger domain; has similarity to Stp1p, Stp2p, and Stp3p
YFR032C-A 1.54
RPL29
Protein component of the large (60S) ribosomal subunit, has similarity to rat L29 ribosomal protein; not essential for translation, but required for proper joining of the large and small ribosomal subunits and for normal translation rate
YDR514C 1.53 Putative protein of unknown function
YGR138C 1.53
TPO2
Polyamine transport protein specific for spermine; localizes to the plasma membrane; transcription of TPO2 is regulated by Haa1p; member of the major facilitator superfamily
YLL028W 1.53
TPO1
Polyamine transporter that recognizes spermine, putrescine, and spermidine; catalyzes uptake of polyamines at alkaline pH and excretion at acidic pH; phosphorylation enhances activity and sorting to the plasma membrane
YJL106W 1.52
IME2
Serine/threonine protein kinase involved in activation of meiosis, associates with Ime1p and mediates its stability, activates Ndt80p; IME2 expression is positively regulated by Ime1p
YIL009W 1.52
FAA3
Long chain fatty acyl-CoA synthetase, has a preference for C16 and C18 fatty acids; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery
YDR382W 1.49
RPP2B
Ribosomal protein P2 beta, a component of the ribosomal stalk, which is involved in the interaction between translational elongation factors and the ribosome; regulates the accumulation of P1 (Rpp1Ap and Rpp1Bp) in the cytoplasm
YOL031C 1.48
SIL1
Nucleotide exchange factor for the endoplasmic reticulum (ER) lumenal Hsp70 chaperone Kar2p, required for protein translocation into the ER; homolog of Yarrowia lipolytica SLS1; GrpE-like protein
YOL127W 1.48
RPL25
Primary rRNA-binding ribosomal protein component of the large (60S) ribosomal subunit, has similarity to E. coli L23 and rat L23a ribosomal proteins; binds to 26S rRNA via a conserved C-terminal motif
YNL300W 1.47 Glycosylphosphatidylinositol-dependent cell wall protein, expression is periodic and decreases in respone to ergosterol perturbation or upon entry into stationary phase; depletion increases resistance to lactic acid
YDR146C 1.47
SWI5
Transcription factor that activates transcription of genes expressed at the M/G1 phase boundary and in G1 phase; localization to the nucleus occurs during G1 and appears to be regulated by phosphorylation by Cdc28p kinase
YOR376W-A 1.46 Putative protein of unknown function; identified by fungal homology and RT-PCR
YDR531W 1.44 Pantothenate kinase (ATP:D-pantothenate 4'-phosphotransferase, EC 2.7.1.33); catalyzes the first committed step in the universal biosynthetic pathway leading to coenzyme A1
YGR037C 1.43
ACB1
Acyl-CoA-binding protein, transports newly synthesized acyl-CoA esters from fatty acid synthetase (Fas1p-Fas2p) to acyl-CoA-consuming processes
YOR320C 1.43
GNT1
N-acetylglucosaminyltransferase capable of modification of N-linked glycans in the Golgi apparatus
YMR108W 1.42
ILV2
Acetolactate synthase, catalyses the first common step in isoleucine and valine biosynthesis and is the target of several classes of inhibitors, localizes to the mitochondria; expression of the gene is under general amino acid control
YKL110C 1.42
KTI12
Protein that plays a role, with Elongator complex, in modification of wobble nucleosides in tRNA; involved in sensitivity to G1 arrest induced by zymocin; interacts with chromatin throughout the genome; also interacts with Cdc19p
YDL192W 1.41
ARF1
ADP-ribosylation factor, GTPase of the Ras superfamily involved in regulation of coated vesicle formation in intracellular trafficking within the Golgi; functionally interchangeable with Arf2p
YGR140W 1.41
CBF2
Essential kinetochore protein, component of the CBF3 multisubunit complex that binds to the CDEIII region of the centromere; Cbf2p also binds to the CDEII region possibly forming a different multimeric complex, ubiquitinated in vivo
YFR031C-A 1.41
RPL2A
Protein component of the large (60S) ribosomal subunit, identical to Rpl2Bp and has similarity to E. coli L2 and rat L8 ribosomal proteins
YBR143C 1.40
SUP45
Polypeptide release factor involved in translation termination; mutant form acts as a recessive omnipotent suppressor
YGR229C 1.39
SMI1
Protein involved in the regulation of cell wall synthesis; proposed to be involved in coordinating cell cycle progression with cell wall integrity
YIR033W 1.39
MGA2
ER membrane protein involved in regulation of OLE1 transcription, acts with homolog Spt23p; inactive ER form dimerizes and one subunit is then activated by ubiquitin/proteasome-dependent processing followed by nuclear targeting
YPL243W 1.38
SRP68
Core component of the signal recognition particle (SRP) ribonucleoprotein (RNP) complex that functions in targeting nascent secretory proteins to the endoplasmic reticulum (ER) membrane
YHR136C 1.35
SPL2
Protein with similarity to cyclin-dependent kinase inhibitors, overproduction suppresses a plc1 null mutation; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern
YNL043C 1.34 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene YIP3/YNL044W
YHR181W 1.34
SVP26
Integral membrane protein of the early Golgi apparatus and endoplasmic reticulum, involved in COP II vesicle transport; may also function to promote retention of proteins in the early Golgi compartment
YIL096C 1.32 Putative protein of unknown function; associates with precursors of the 60S ribosomal subunit
YJL153C 1.32
INO1
Inositol 1-phosphate synthase, involved in synthesis of inositol phosphates and inositol-containing phospholipids; transcription is coregulated with other phospholipid biosynthetic genes by Ino2p and Ino4p, which bind the UASINO DNA element
YOR130C 1.32
ORT1
Ornithine transporter of the mitochondrial inner membrane, exports ornithine from mitochondria as part of arginine biosynthesis; human ortholog is associated with hyperammonaemia-hyperornithinaemia-homocitrullinuria (HHH) syndrome
YMR241W 1.31
YHM2
Mitochondrial DNA-binding protein, component of the mitochondrial nucleoid structure, involved in mtDNA replication and segregation of mitochondrial genomes; member of the mitochondrial carrier protein family
YGR159C 1.30
NSR1
Nucleolar protein that binds nuclear localization sequences, required for pre-rRNA processing and ribosome biogenesis
YOR153W 1.29
PDR5
Plasma membrane ATP-binding cassette (ABC) transporter, short-lived multidrug transporter actively regulated by Pdr1p; also involved in steroid transport, cation resistance, and cellular detoxification during exponential growth
YPR014C 1.29 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; YPR014C is not an essential gene
YLR180W 1.28
SAM1
S-adenosylmethionine synthetase, catalyzes transfer of the adenosyl group of ATP to the sulfur atom of methionine; one of two differentially regulated isozymes (Sam1p and Sam2p)
YOR009W 1.28
TIR4
Cell wall mannoprotein of the Srp1p/Tip1p family of serine-alanine-rich proteins; expressed under anaerobic conditions and required for anaerobic growth; transcription is also induced by cold shock
YLR154C 1.28
RNH203
Ribonuclease H2 subunit, required for RNase H2 activity
YJL148W 1.27
RPA34
RNA polymerase I subunit A34.5
YNL231C 1.27
PDR16
Phosphatidylinositol transfer protein (PITP) controlled by the multiple drug resistance regulator Pdr1p, localizes to lipid particles and microsomes, controls levels of various lipids, may regulate lipid synthesis, homologous to Pdr17p
YBR092C 1.27
PHO3
Constitutively expressed acid phosphatase similar to Pho5p; brought to the cell surface by transport vesicles; hydrolyzes thiamin phosphates in the periplasmic space, increasing cellular thiamin uptake; expression is repressed by thiamin
YKR074W 1.27
AIM29
Putative protein of unknown function; epitope-tagged protein localizes to the cytoplasm; null mutant displays increased frequency of mitochondrial genome loss (petite formation)
YER056C-A 1.27
RPL34A
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl34Bp and has similarity to rat L34 ribosomal protein
YNR053C 1.26
NOG2
Putative GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation
YMR102C 1.26 Protein of unknown function; transcription is activated by paralogous transcription factors Yrm1p and Yrr1p along with genes involved in multidrug resistance; mutant shows increased resistance to azoles; YMR102C is not an essential gene
YDR345C 1.26
HXT3
Low affinity glucose transporter of the major facilitator superfamily, expression is induced in low or high glucose conditions
YNL327W 1.26
EGT2
Glycosylphosphatidylinositol (GPI)-anchored cell wall endoglucanase required for proper cell separation after cytokinesis, expression is activated by Swi5p and tightly regulated in a cell cycle-dependent manner
YBR283C 1.25
SSH1
Subunit of the Ssh1 translocon complex; Sec61p homolog involved in co-translational pathway of protein translocation; not essential
YLR257W 1.24 Putative protein of unknown function
YMR006C 1.24
PLB2
Phospholipase B (lysophospholipase) involved in phospholipid metabolism; displays transacylase activity in vitro; overproduction confers resistance to lysophosphatidylcholine
YBR023C 1.23
CHS3
Chitin synthase III, catalyzes the transfer of N-acetylglucosamine (GlcNAc) to chitin; required for synthesis of the majority of cell wall chitin, the chitin ring during bud emergence, and spore wall chitosan
YIL009C-A 1.23
EST3
Component of the telomerase holoenzyme, involved in telomere replication
YPR157W 1.23 Putative protein of unknown function; induced by treatment with 8-methoxypsoralen and UVA irradiation
YKL182W 1.22
FAS1
Beta subunit of fatty acid synthetase, which catalyzes the synthesis of long-chain saturated fatty acids; contains acetyltransacylase, dehydratase, enoyl reductase, malonyl transacylase, and palmitoyl transacylase activities
YDR384C 1.22
ATO3
Plasma membrane protein, regulation pattern suggests a possible role in export of ammonia from the cell; phosphorylated in mitochondria; member of the TC 9.B.33 YaaH family of putative transporters
YJL158C 1.22
CIS3
Mannose-containing glycoprotein constituent of the cell wall; member of the PIR (proteins with internal repeats) family
YLR186W 1.21
EMG1
Member of the alpha/beta knot fold methyltransferase superfamily; required for maturation of 18S rRNA and for 40S ribosome production; interacts with RNA and with S-adenosylmethionine; associates with spindle/microtubules; forms homodimers
YOR375C 1.20
GDH1
NADP(+)-dependent glutamate dehydrogenase, synthesizes glutamate from ammonia and alpha-ketoglutarate; rate of alpha-ketoglutarate utilization differs from Gdh3p; expression regulated by nitrogen and carbon sources
YKL063C 1.20 Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the Golgi
YPL256C 1.18
CLN2
G1 cyclin involved in regulation of the cell cycle; activates Cdc28p kinase to promote the G1 to S phase transition; late G1 specific expression depends on transcription factor complexes, MBF (Swi6p-Mbp1p) and SBF (Swi6p-Swi4p)
YGL102C 1.17 Dubious open reading frame unlikely to encode a functional protein; overlaps 3' end of essential RPL28 gene encoding a large subunit ribosomal protein
YPR043W 1.17
RPL43A
Protein component of the large (60S) ribosomal subunit, identical to Rpl43Bp and has similarity to rat L37a ribosomal protein; null mutation confers a dominant lethal phenotype
YPR074C 1.17
TKL1
Transketolase, similar to Tkl2p; catalyzes conversion of xylulose-5-phosphate and ribose-5-phosphate to sedoheptulose-7-phosphate and glyceraldehyde-3-phosphate in the pentose phosphate pathway; needed for synthesis of aromatic amino acids
YKL166C 1.16
TPK3
cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; partially redundant with Tpk1p and Tpk2p
YBR210W 1.16
ERV15
Protein involved in export of proteins from the endoplasmic reticulum, has similarity to Erv14p
YJR112W 1.15
NNF1
Essential component of the MIND kinetochore complex (Mtw1p Including Nnf1p-Nsl1p-Dsn1p) which joins kinetochore subunits contacting DNA to those contacting microtubules; required for accurate chromosome segregation
YHL028W 1.14
WSC4
ER membrane protein involved in the translocation of soluble secretory proteins and insertion of membrane proteins into the ER membrane; may also have a role in the stress response but has only partial functional overlap with WSC1-3
YBR238C 1.14 Mitochondrial membrane protein with similarity to Rmd9p; not required for respiratory growth but causes a synthetic respiratory defect in combination with rmd9 mutations; transcriptionally up-regulated by TOR; deletion increases life span
YMR083W 1.13
ADH3
Mitochondrial alcohol dehydrogenase isozyme III; involved in the shuttling of mitochondrial NADH to the cytosol under anaerobic conditions and ethanol production
YER147C-A 1.12 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YDR279W 1.10
RNH202
Ribonuclease H2 subunit, required for RNase H2 activity
YOR272W 1.10
YTM1
Constituent of 66S pre-ribosomal particles, required for maturation of the large ribosomal subunit
YGR106C 1.10
VOA1
Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuolar memebrane
YDR120C 1.08
TRM1
tRNA methyltransferase, localizes to both the nucleus and mitochondrion to produce the modified base N2,N2-dimethylguanosine in tRNAs in both compartments
YLR420W 1.08
URA4
Dihydroorotase, catalyzes the third enzymatic step in the de novo biosynthesis of pyrimidines, converting carbamoyl-L-aspartate into dihydroorotate
YPL112C 1.07
PEX25
Peripheral peroxisomal membrane peroxin required for the regulation of peroxisome size and maintenance, recruits GTPase Rho1p to peroxisomes, induced by oleate, interacts with homologous protein Pex27p
YOR137C 1.07
SIA1
Protein of unassigned function involved in activation of the Pma1p plasma membrane H+-ATPase by glucose
YJL029C 1.05
VPS53
Component of the GARP (Golgi-associated retrograde protein) complex, Vps51p-Vps52p-Vps53p-Vps54p, which is required for the recycling of proteins from endosomes to the late Golgi; required for vacuolar protein sorting
YDL074C 1.04
BRE1
E3 ubiquitin ligase for Rad6p, required for the ubiquitination of histone H2B, recruitment of Rad6p to promoter chromatin and subsequent methylation of histone H3 (on K4 and K79), contains RING finger domain
YOR185C 1.04
GSP2
GTP binding protein (mammalian Ranp homolog) involved in the maintenance of nuclear organization, RNA processing and transport; interacts with Kap121p, Kap123p and Pdr6p (karyophilin betas); Gsp1p homolog that is not required for viability
YJL035C 1.04
TAD2
Subunit of tRNA-specific adenosine-34 deaminase, forms a heterodimer with Tad3p that converts adenosine to inosine at the wobble position of several tRNAs
YGR139W 1.03 Dubious ORF unlikely to encode a functional protein, based on available experimental and comparative sequence data
YPR029C 1.03
APL4
Gamma-adaptin, large subunit of the clathrin-associated protein (AP-1) complex; binds clathrin; involved in vesicle mediated transport
YOR263C 1.02 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF DES3/YOR264W
YDL226C 1.02
GCS1
ADP-ribosylation factor GTPase activating protein (ARF GAP), involved in ER-Golgi transport; shares functional similarity with Glo3p
YGL001C 1.02
ERG26
C-3 sterol dehydrogenase, catalyzes the second of three steps required to remove two C-4 methyl groups from an intermediate in ergosterol biosynthesis
YBR087W 1.02
RFC5
Subunit of heteropentameric Replication factor C (RF-C), which is a DNA binding protein and ATPase that acts as a clamp loader of the proliferating cell nuclear antigen (PCNA) processivity factor for DNA polymerases delta and epsilon
YPL227C 1.02
ALG5
UDP-glucose:dolichyl-phosphate glucosyltransferase, involved in asparagine-linked glycosylation in the endoplasmic reticulum
YER070W 1.00
RNR1
One of two large regulatory subunits of ribonucleotide-diphosphate reductase; the RNR complex catalyzes rate-limiting step in dNTP synthesis, regulated by DNA replication and DNA damage checkpoint pathways via localization of small subunits
YDR074W 0.99
TPS2
Phosphatase subunit of the trehalose-6-phosphate synthase/phosphatase complex, which synthesizes the storage carbohydrate trehalose; expression is induced by stress conditions and repressed by the Ras-cAMP pathway
YER131W 0.99
RPS26B
Protein component of the small (40S) ribosomal subunit; nearly identical to Rps26Ap and has similarity to rat S26 ribosomal protein
YKR043C 0.99 Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus
YGL189C 0.99
RPS26A
Protein component of the small (40S) ribosomal subunit; nearly identical to Rps26Bp and has similarity to rat S26 ribosomal protein
YFL016C 0.98
MDJ1
Co-chaperone that stimulates the ATPase activity of the HSP70 protein Ssc1p; involved in protein folding/refolding in the mitochodrial matrix; required for proteolysis of misfolded proteins; member of the HSP40 (DnaJ) family of chaperones
YLR183C 0.98
TOS4
Transcription factor that binds to a number of promoter regions, particularly promoters of some genes involved in pheromone response and cell cycle; potential Cdc28p substrate; expression is induced in G1 by bound SBF
YPR170W-B 0.97 Putative protein of unknown function, conserved in fungi; partially overlaps the dubious genes YPR169W-A, YPR170W-A and YRP170C
YDL137W 0.97
ARF2
ADP-ribosylation factor, GTPase of the Ras superfamily involved in regulation of coated formation vesicles in intracellular trafficking within the Golgi; functionally interchangeable with Arf1p
YLR154W-B 0.97 Dubious open reading frame unlikely to encode a protein; encoded within the the 25S rRNA gene on the opposite strand
YGR097W 0.96
ASK10
Component of the RNA polymerase II holoenzyme, phosphorylated in response to oxidative stress; has a role in destruction of Ssn8p, which relieves repression of stress-response genes
YGR255C 0.96
COQ6
Putative flavin-dependent monooxygenase, involved in ubiquinone (Coenzyme Q) biosynthesis; localizes to the matrix face of the mitochondrial inner membrane in a large complex with other ubiquinone biosynthetic enzymes
YNL079C 0.95
TPM1
Major isoform of tropomyosin; binds to and stabilizes actin cables and filaments, which direct polarized cell growth and the distribution of several organelles; acetylated by the NatB complex and acetylated form binds actin most efficiently
YHR128W 0.95
FUR1
Uracil phosphoribosyltransferase, synthesizes UMP from uracil; involved in the pyrimidine salvage pathway
YNL087W 0.95
TCB2
Bud-specific protein with a potential role in membrane trafficking; GFP-fusion protein migrates from the cell surface to intracellular vesicles near vacuole; contains 3 calcium and lipid binding domains; mRNA is targeted to the bud
YOR362C 0.94
PRE10
Alpha 7 subunit of the 20S proteasome
YPL019C 0.93
VTC3
Vacuolar membrane protein involved in vacuolar polyphosphate accumulation; functions as a regulator of vacuolar H+-ATPase activity and vacuolar transporter chaperones; involved in non-autophagic vacuolar fusion
YLR154W-A 0.92 Dubious open reading frame unlikely to encode a protein; encoded within the the 25S rRNA gene on the opposite strand
YBR096W 0.92 Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the ER
YLR185W 0.92
RPL37A
Protein component of the large (60S) ribosomal subunit, has similarity to Rpl37Bp and to rat L37 ribosomal protein
YGR157W 0.91
CHO2
Phosphatidylethanolamine methyltransferase (PEMT), catalyzes the first step in the conversion of phosphatidylethanolamine to phosphatidylcholine during the methylation pathway of phosphatidylcholine biosynthesis
YDL121C 0.91 Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic retiuculum; YDL121C is not an essential protein
YMR320W 0.90 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
YDL100C 0.90
GET3
Guanine nucleotide exchange factor for Gpa1p; amplifies G protein signaling; subunit of the GET complex, which is involved in Golgi to ER trafficking; has low-level ATPase activity and is involved in resistance to heat and metal stress
YMR072W 0.90
ABF2
Mitochondrial DNA-binding protein involved in mitochondrial DNA replication and recombination, member of HMG1 DNA-binding protein family; activity may be regulated by protein kinase A phosphorylation
YPL086C 0.88
ELP3
Subunit of Elongator complex, which is required for modification of wobble nucleosides in tRNA; exhibits histone acetyltransferase activity that is directed to histones H3 and H4; disruption confers resistance to K. lactis zymotoxin
YJL138C 0.88
TIF2
Translation initiation factor eIF4A, identical to Tif1p; DEA(D/H)-box RNA helicase that couples ATPase activity to RNA binding and unwinding; forms a dumbbell structure of two compact domains connected by a linker; interacts with eIF4G
YOR230W 0.88
WTM1
Transcriptional modulator involved in regulation of meiosis, silencing, and expression of RNR genes; required for nuclear localization of the ribonucleotide reductase small subunit Rnr2p and Rnr4p; contains WD repeats
YIL169C 0.88 Putative protein of unknown function; serine/threonine rich and highly similar to YOL155C, a putative glucan alpha-1,4-glucosidase; transcript is induced in both high and low pH environments; YIL169C is a non-essential gene
YHR007C 0.88
ERG11
Lanosterol 14-alpha-demethylase, catalyzes the C-14 demethylation of lanosterol to form 4,4''-dimethyl cholesta-8,14,24-triene-3-beta-ol in the ergosterol biosynthesis pathway; member of the cytochrome P450 family

Network of associatons between targets according to the STRING database.

First level regulatory network of ECM23

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 9.8 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
1.3 9.4 GO:0010696 positive regulation of spindle pole body separation(GO:0010696)
1.0 3.1 GO:0043066 negative regulation of apoptotic process(GO:0043066) negative regulation of programmed cell death(GO:0043069) negative regulation of cell death(GO:0060548)
0.9 3.4 GO:0000296 spermine transport(GO:0000296)
0.9 3.4 GO:0090337 regulation of formin-nucleated actin cable assembly(GO:0090337) positive regulation of formin-nucleated actin cable assembly(GO:0090338)
0.8 13.7 GO:0051029 rRNA export from nucleus(GO:0006407) rRNA transport(GO:0051029)
0.7 2.2 GO:0045901 positive regulation of translational elongation(GO:0045901)
0.7 2.1 GO:0009298 GDP-mannose biosynthetic process(GO:0009298) GDP-mannose metabolic process(GO:0019673)
0.7 2.0 GO:0033559 unsaturated fatty acid biosynthetic process(GO:0006636) unsaturated fatty acid metabolic process(GO:0033559)
0.6 2.6 GO:0019287 isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287) isopentenyl diphosphate metabolic process(GO:0046490)
0.6 3.1 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.6 1.7 GO:0001676 long-chain fatty acid metabolic process(GO:0001676)
0.6 4.5 GO:0000372 Group I intron splicing(GO:0000372) RNA splicing, via transesterification reactions with guanosine as nucleophile(GO:0000376)
0.6 2.2 GO:0015909 long-chain fatty acid transport(GO:0015909)
0.5 4.7 GO:0042219 cellular modified amino acid catabolic process(GO:0042219)
0.5 2.0 GO:0046898 response to organic cyclic compound(GO:0014070) response to cycloheximide(GO:0046898)
0.5 1.9 GO:0042990 regulation of transcription factor import into nucleus(GO:0042990)
0.5 1.9 GO:0032211 negative regulation of telomere maintenance via telomerase(GO:0032211) negative regulation of telomere maintenance via telomere lengthening(GO:1904357)
0.5 2.8 GO:0009099 valine biosynthetic process(GO:0009099)
0.5 2.8 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.5 0.5 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.4 1.7 GO:0046500 S-adenosylmethionine metabolic process(GO:0046500)
0.4 4.0 GO:0006797 polyphosphate metabolic process(GO:0006797)
0.4 1.2 GO:0070475 rRNA base methylation(GO:0070475)
0.4 3.5 GO:0042538 hyperosmotic salinity response(GO:0042538)
0.4 1.6 GO:0010138 pyrimidine ribonucleotide salvage(GO:0010138) pyrimidine nucleotide salvage(GO:0032262) pyrimidine nucleoside salvage(GO:0043097) UMP salvage(GO:0044206)
0.4 0.8 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.4 1.9 GO:0035066 DNA replication-independent nucleosome assembly(GO:0006336) positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.4 2.6 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.4 0.4 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.4 49.5 GO:0002181 cytoplasmic translation(GO:0002181)
0.4 3.2 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.4 3.2 GO:0070525 tRNA threonylcarbamoyladenosine metabolic process(GO:0070525)
0.3 1.0 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571) mitotic G1/S transition checkpoint(GO:0044819)
0.3 0.3 GO:0071474 cellular hyperosmotic response(GO:0071474)
0.3 4.0 GO:0030011 maintenance of cell polarity(GO:0030011)
0.3 1.0 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037) actin filament reorganization(GO:0090527)
0.3 1.0 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.3 1.0 GO:0009186 deoxyribonucleoside diphosphate metabolic process(GO:0009186)
0.3 0.3 GO:0033239 negative regulation of cellular amine metabolic process(GO:0033239)
0.3 1.6 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.3 0.3 GO:0071482 cellular response to radiation(GO:0071478) cellular response to light stimulus(GO:0071482)
0.3 2.1 GO:0006835 dicarboxylic acid transport(GO:0006835)
0.3 1.5 GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity(GO:0043433)
0.3 0.9 GO:1904667 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051436) regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051439) negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.3 1.2 GO:0098740 agglutination involved in conjugation with cellular fusion(GO:0000752) agglutination involved in conjugation(GO:0000771) heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157) cell-cell adhesion(GO:0098609) adhesion between unicellular organisms(GO:0098610) multi organism cell adhesion(GO:0098740) cell-cell adhesion via plasma-membrane adhesion molecules(GO:0098742)
0.3 0.9 GO:0023021 termination of signal transduction(GO:0023021) termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.3 1.4 GO:0031496 positive regulation of cell fate commitment(GO:0010455) positive regulation of mating type switching(GO:0031496) positive regulation of cell differentiation(GO:0045597)
0.3 1.4 GO:0031032 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin structure organization(GO:0031032) actomyosin contractile ring organization(GO:0044837)
0.3 1.9 GO:0098754 detoxification(GO:0098754)
0.3 1.3 GO:0060304 regulation of phosphatidylinositol dephosphorylation(GO:0060304) endoplasmic reticulum membrane organization(GO:0090158)
0.3 8.6 GO:0016126 steroid biosynthetic process(GO:0006694) sterol biosynthetic process(GO:0016126)
0.3 5.9 GO:0002097 tRNA wobble base modification(GO:0002097) tRNA wobble uridine modification(GO:0002098)
0.3 0.3 GO:0070649 parallel actin filament bundle assembly(GO:0030046) formin-nucleated actin cable assembly(GO:0070649)
0.3 1.3 GO:0000390 spliceosomal complex disassembly(GO:0000390)
0.2 1.2 GO:0006021 inositol biosynthetic process(GO:0006021)
0.2 2.2 GO:0000917 barrier septum assembly(GO:0000917) cell septum assembly(GO:0090529)
0.2 2.9 GO:0006415 translational termination(GO:0006415)
0.2 1.4 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.2 0.7 GO:2000879 regulation of oligopeptide transport by regulation of transcription from RNA polymerase II promoter(GO:0035950) negative regulation of oligopeptide transport by negative regulation of transcription from RNA polymerase II promoter(GO:0035952) regulation of dipeptide transport by regulation of transcription from RNA polymerase II promoter(GO:0035953) negative regulation of dipeptide transport by negative regulation of transcription from RNA polymerase II promoter(GO:0035955) negative regulation of oligopeptide transport(GO:2000877) negative regulation of dipeptide transport(GO:2000879)
0.2 1.4 GO:0007119 budding cell isotropic bud growth(GO:0007119)
0.2 0.7 GO:0000101 sulfur amino acid transport(GO:0000101)
0.2 0.7 GO:0071454 response to anoxia(GO:0034059) cellular response to anoxia(GO:0071454)
0.2 0.2 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.2 6.5 GO:0009303 rRNA transcription(GO:0009303)
0.2 0.4 GO:0015786 pyrimidine nucleotide-sugar transport(GO:0015781) UDP-glucose transport(GO:0015786)
0.2 1.5 GO:0009262 deoxyribonucleotide metabolic process(GO:0009262) deoxyribonucleotide biosynthetic process(GO:0009263)
0.2 0.9 GO:0010674 negative regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle(GO:0010674)
0.2 1.1 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.2 0.4 GO:0015677 copper ion import(GO:0015677)
0.2 0.6 GO:0000467 exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467)
0.2 2.0 GO:0007109 obsolete cytokinesis, completion of separation(GO:0007109)
0.2 1.0 GO:0045860 positive regulation of protein kinase activity(GO:0045860)
0.2 0.8 GO:0042256 mature ribosome assembly(GO:0042256)
0.2 0.6 GO:0048194 Golgi vesicle budding(GO:0048194)
0.2 0.6 GO:0006531 aspartate metabolic process(GO:0006531)
0.2 0.6 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.2 1.0 GO:0072668 obsolete tubulin complex biogenesis(GO:0072668)
0.2 0.4 GO:0030835 regulation of actin filament depolymerization(GO:0030834) negative regulation of actin filament depolymerization(GO:0030835) barbed-end actin filament capping(GO:0051016) actin filament capping(GO:0051693)
0.2 0.7 GO:0070072 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.2 0.2 GO:0034067 protein localization to Golgi apparatus(GO:0034067)
0.2 0.4 GO:0016093 polyprenol metabolic process(GO:0016093) polyprenol biosynthetic process(GO:0016094) dolichol metabolic process(GO:0019348) dolichol biosynthetic process(GO:0019408)
0.2 0.7 GO:0030497 fatty acid elongation(GO:0030497)
0.2 2.8 GO:0030488 tRNA methylation(GO:0030488)
0.2 0.5 GO:0015680 intracellular copper ion transport(GO:0015680)
0.2 0.7 GO:0055129 L-proline biosynthetic process(GO:0055129)
0.2 1.2 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.2 0.7 GO:0046497 nicotinate nucleotide biosynthetic process(GO:0019357) nicotinate nucleotide salvage(GO:0019358) pyridine nucleotide salvage(GO:0019365) nicotinate nucleotide metabolic process(GO:0046497)
0.2 0.3 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.2 0.3 GO:0033262 regulation of nuclear cell cycle DNA replication(GO:0033262)
0.2 1.0 GO:0006621 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.2 0.8 GO:0007535 donor selection(GO:0007535)
0.2 1.4 GO:0000022 mitotic spindle elongation(GO:0000022) spindle elongation(GO:0051231)
0.2 0.8 GO:0044038 cell wall macromolecule biosynthetic process(GO:0044038) cellular component macromolecule biosynthetic process(GO:0070589)
0.2 0.3 GO:1903322 positive regulation of protein ubiquitination(GO:0031398) positive regulation of protein modification by small protein conjugation or removal(GO:1903322)
0.2 2.0 GO:0010383 cell wall chitin metabolic process(GO:0006037) cell wall polysaccharide metabolic process(GO:0010383)
0.2 1.1 GO:0006458 'de novo' protein folding(GO:0006458)
0.1 0.6 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.1 0.1 GO:0032886 regulation of microtubule-based process(GO:0032886) regulation of microtubule cytoskeleton organization(GO:0070507)
0.1 1.0 GO:0009636 response to toxic substance(GO:0009636)
0.1 0.6 GO:0060277 obsolete negative regulation of transcription involved in G1 phase of mitotic cell cycle(GO:0060277)
0.1 0.4 GO:0036170 filamentous growth of a population of unicellular organisms in response to starvation(GO:0036170) regulation of filamentous growth of a population of unicellular organisms in response to starvation(GO:1900434) positive regulation of filamentous growth of a population of unicellular organisms in response to starvation(GO:1900436)
0.1 0.9 GO:0046037 GMP metabolic process(GO:0046037)
0.1 0.4 GO:0097502 protein mannosylation(GO:0035268) protein O-linked mannosylation(GO:0035269) mannosylation(GO:0097502)
0.1 1.8 GO:0031110 regulation of microtubule polymerization or depolymerization(GO:0031110)
0.1 0.7 GO:0046219 tryptophan biosynthetic process(GO:0000162) indole-containing compound biosynthetic process(GO:0042435) indolalkylamine biosynthetic process(GO:0046219)
0.1 0.5 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
0.1 0.1 GO:0090342 regulation of cell aging(GO:0090342) regulation of replicative cell aging(GO:1900062)
0.1 1.7 GO:0007120 axial cellular bud site selection(GO:0007120)
0.1 1.5 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.1 0.4 GO:0046416 D-amino acid metabolic process(GO:0046416)
0.1 6.1 GO:0007124 pseudohyphal growth(GO:0007124)
0.1 2.5 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.1 0.4 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.1 2.0 GO:0071042 nuclear polyadenylation-dependent mRNA catabolic process(GO:0071042) polyadenylation-dependent mRNA catabolic process(GO:0071047)
0.1 0.6 GO:0043102 L-methionine biosynthetic process from methylthioadenosine(GO:0019509) amino acid salvage(GO:0043102) L-methionine salvage(GO:0071267)
0.1 0.3 GO:0033865 coenzyme A metabolic process(GO:0015936) nucleoside bisphosphate metabolic process(GO:0033865) ribonucleoside bisphosphate metabolic process(GO:0033875) purine nucleoside bisphosphate metabolic process(GO:0034032)
0.1 1.3 GO:0006272 leading strand elongation(GO:0006272)
0.1 0.9 GO:0032042 mitochondrial DNA metabolic process(GO:0032042)
0.1 8.0 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.1 1.3 GO:0006446 regulation of translational initiation(GO:0006446)
0.1 0.8 GO:0015791 polyol transport(GO:0015791)
0.1 0.4 GO:1900101 regulation of endoplasmic reticulum unfolded protein response(GO:1900101)
0.1 4.1 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.1 1.5 GO:0006614 cotranslational protein targeting to membrane(GO:0006613) SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.1 1.9 GO:0010833 telomere maintenance via telomere lengthening(GO:0010833)
0.1 3.0 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.1 0.1 GO:0006952 defense response(GO:0006952)
0.1 0.8 GO:0005992 trehalose biosynthetic process(GO:0005992) oligosaccharide biosynthetic process(GO:0009312) disaccharide biosynthetic process(GO:0046351)
0.1 0.7 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501)
0.1 0.5 GO:0042274 ribosomal small subunit biogenesis(GO:0042274)
0.1 0.4 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.1 0.4 GO:0042991 transcription factor import into nucleus(GO:0042991)
0.1 1.6 GO:0009304 tRNA transcription(GO:0009304) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.1 1.8 GO:0006633 fatty acid biosynthetic process(GO:0006633)
0.1 1.4 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1 0.5 GO:0000743 nuclear migration involved in conjugation with cellular fusion(GO:0000743)
0.1 0.3 GO:0009371 positive regulation of transcription from RNA polymerase II promoter by pheromones(GO:0007329) positive regulation of transcription by pheromones(GO:0009371)
0.1 0.9 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.1 0.3 GO:0031565 obsolete cytokinesis checkpoint(GO:0031565)
0.1 0.3 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654) phosphatidic acid metabolic process(GO:0046473)
0.1 0.4 GO:0006898 receptor-mediated endocytosis(GO:0006898)
0.1 0.3 GO:0015693 magnesium ion transport(GO:0015693)
0.1 0.4 GO:0001402 signal transduction involved in filamentous growth(GO:0001402)
0.1 2.1 GO:1904029 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.1 1.9 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.1 0.4 GO:0070588 calcium ion transmembrane transport(GO:0070588)
0.1 0.2 GO:0018195 peptidyl-arginine modification(GO:0018195) peptidyl-arginine methylation(GO:0018216)
0.1 0.4 GO:0043555 regulation of translation in response to stress(GO:0043555)
0.1 0.6 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.1 0.1 GO:0032368 regulation of lipid transport(GO:0032368)
0.1 0.4 GO:0016479 negative regulation of transcription from RNA polymerase I promoter(GO:0016479)
0.1 0.6 GO:0016559 peroxisome fission(GO:0016559)
0.1 1.0 GO:0001100 negative regulation of exit from mitosis(GO:0001100)
0.1 0.9 GO:1901661 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) ketone biosynthetic process(GO:0042181) quinone metabolic process(GO:1901661) quinone biosynthetic process(GO:1901663)
0.1 0.3 GO:1901925 cellular response to biotic stimulus(GO:0071216) response to cell cycle checkpoint signaling(GO:0072396) response to mitotic cell cycle checkpoint signaling(GO:0072414) response to spindle checkpoint signaling(GO:0072417) response to mitotic spindle checkpoint signaling(GO:0072476) response to mitotic cell cycle spindle assembly checkpoint signaling(GO:0072479) response to spindle assembly checkpoint signaling(GO:0072485) negative regulation of protein import into nucleus during spindle assembly checkpoint(GO:1901925)
0.1 0.9 GO:0007117 budding cell bud growth(GO:0007117)
0.1 0.6 GO:0070481 nuclear-transcribed mRNA catabolic process, non-stop decay(GO:0070481)
0.1 0.2 GO:0031118 rRNA pseudouridine synthesis(GO:0031118)
0.1 0.3 GO:0009423 chorismate biosynthetic process(GO:0009423)
0.1 0.9 GO:0015918 sterol transport(GO:0015918)
0.1 0.2 GO:0019379 sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin)(GO:0019379) sulfate reduction(GO:0019419)
0.1 1.3 GO:0006184 obsolete GTP catabolic process(GO:0006184)
0.1 1.6 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.1 0.4 GO:0034503 protein localization to nucleolar rDNA repeats(GO:0034503)
0.1 1.8 GO:0006400 tRNA modification(GO:0006400)
0.1 0.7 GO:0034965 intronic snoRNA processing(GO:0031070) intronic box C/D snoRNA processing(GO:0034965)
0.1 0.4 GO:0007009 plasma membrane organization(GO:0007009)
0.1 0.1 GO:0006048 UDP-N-acetylglucosamine metabolic process(GO:0006047) UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.1 0.2 GO:0034402 recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex(GO:0034402)
0.1 0.2 GO:0051664 nuclear pore distribution(GO:0031081) nuclear pore localization(GO:0051664)
0.1 0.4 GO:0009098 leucine metabolic process(GO:0006551) leucine biosynthetic process(GO:0009098)
0.1 1.1 GO:0018208 protein peptidyl-prolyl isomerization(GO:0000413) peptidyl-proline modification(GO:0018208)
0.1 6.0 GO:0006364 rRNA processing(GO:0006364)
0.1 0.3 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.1 0.7 GO:0072593 reactive oxygen species metabolic process(GO:0072593)
0.1 1.5 GO:0006413 translational initiation(GO:0006413)
0.1 0.7 GO:0008033 tRNA processing(GO:0008033)
0.1 0.6 GO:0045047 protein targeting to ER(GO:0045047)
0.1 0.4 GO:0043628 ncRNA 3'-end processing(GO:0043628)
0.1 0.3 GO:0031134 sister chromatid biorientation(GO:0031134)
0.1 0.2 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 1.3 GO:0045324 late endosome to vacuole transport(GO:0045324)
0.1 0.8 GO:0006353 DNA-templated transcription, termination(GO:0006353)
0.1 0.3 GO:0016574 histone ubiquitination(GO:0016574)
0.1 0.5 GO:0006360 transcription from RNA polymerase I promoter(GO:0006360)
0.1 0.1 GO:0046470 phosphatidylcholine metabolic process(GO:0046470)
0.1 0.6 GO:0044774 mitotic DNA integrity checkpoint(GO:0044774)
0.1 2.3 GO:0055072 iron ion homeostasis(GO:0055072)
0.1 0.2 GO:0015883 FAD transport(GO:0015883)
0.1 0.5 GO:0043094 cellular metabolic compound salvage(GO:0043094)
0.1 1.3 GO:1902593 protein import into nucleus(GO:0006606) nuclear import(GO:0051170) single-organism nuclear import(GO:1902593)
0.1 0.5 GO:0006379 mRNA cleavage(GO:0006379)
0.1 0.4 GO:0030474 spindle pole body duplication(GO:0030474)
0.1 0.4 GO:0006855 drug transmembrane transport(GO:0006855)
0.0 0.2 GO:0006972 hyperosmotic response(GO:0006972)
0.0 0.7 GO:0007020 microtubule nucleation(GO:0007020) microtubule polymerization(GO:0046785)
0.0 0.5 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 0.1 GO:0051220 cytoplasmic sequestering of protein(GO:0051220)
0.0 0.6 GO:0051666 actin cortical patch localization(GO:0051666)
0.0 0.2 GO:0070941 eisosome assembly(GO:0070941)
0.0 0.1 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.2 GO:0006596 polyamine biosynthetic process(GO:0006596)
0.0 0.1 GO:0009373 regulation of transcription by pheromones(GO:0009373) negative regulation of transcription by pheromones(GO:0045996) regulation of transcription from RNA polymerase II promoter by pheromones(GO:0046019) negative regulation of transcription from RNA polymerase II promoter by pheromones(GO:0046020)
0.0 0.1 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.1 GO:0030837 negative regulation of actin filament polymerization(GO:0030837) negative regulation of protein polymerization(GO:0032272)
0.0 0.1 GO:0006378 mRNA polyadenylation(GO:0006378)
0.0 0.2 GO:0006771 riboflavin metabolic process(GO:0006771) riboflavin biosynthetic process(GO:0009231)
0.0 0.2 GO:0018342 protein prenylation(GO:0018342) prenylation(GO:0097354)
0.0 0.2 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.0 GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418)
0.0 0.2 GO:0043007 maintenance of rDNA(GO:0043007)
0.0 0.2 GO:0009306 protein secretion(GO:0009306)
0.0 0.1 GO:2001021 regulation of cell cycle checkpoint(GO:1901976) negative regulation of cell cycle checkpoint(GO:1901977) regulation of DNA damage checkpoint(GO:2000001) negative regulation of DNA damage checkpoint(GO:2000002) negative regulation of response to DNA damage stimulus(GO:2001021)
0.0 0.2 GO:0042168 porphyrin-containing compound metabolic process(GO:0006778) porphyrin-containing compound biosynthetic process(GO:0006779) heme biosynthetic process(GO:0006783) tetrapyrrole metabolic process(GO:0033013) tetrapyrrole biosynthetic process(GO:0033014) heme metabolic process(GO:0042168)
0.0 0.1 GO:0031647 regulation of protein stability(GO:0031647)
0.0 0.1 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.1 GO:0048313 Golgi inheritance(GO:0048313)
0.0 0.1 GO:0009082 branched-chain amino acid biosynthetic process(GO:0009082)
0.0 0.1 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 0.1 GO:0006825 copper ion transport(GO:0006825)
0.0 0.5 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.2 GO:0070058 tRNA gene clustering(GO:0070058)
0.0 0.1 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 0.1 GO:0009088 threonine biosynthetic process(GO:0009088)
0.0 0.2 GO:0006547 histidine biosynthetic process(GO:0000105) histidine metabolic process(GO:0006547) imidazole-containing compound metabolic process(GO:0052803)
0.0 0.2 GO:0006012 galactose metabolic process(GO:0006012)
0.0 0.1 GO:0071028 nuclear mRNA surveillance(GO:0071028)
0.0 0.1 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.0 0.0 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972) posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.0 0.4 GO:0043620 regulation of transcription from RNA polymerase II promoter in response to stress(GO:0043618) regulation of DNA-templated transcription in response to stress(GO:0043620)
0.0 0.2 GO:0042559 folic acid-containing compound biosynthetic process(GO:0009396) pteridine-containing compound biosynthetic process(GO:0042559)
0.0 0.4 GO:0040020 regulation of meiotic nuclear division(GO:0040020)
0.0 0.1 GO:0055078 cellular sodium ion homeostasis(GO:0006883) sodium ion homeostasis(GO:0055078)
0.0 0.1 GO:0016036 cellular response to phosphate starvation(GO:0016036)
0.0 0.1 GO:0006517 protein deglycosylation(GO:0006517)
0.0 0.1 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.2 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.1 GO:0046015 regulation of transcription by glucose(GO:0046015)
0.0 0.2 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.0 GO:0090110 cargo loading into vesicle(GO:0035459) cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.1 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 0.1 GO:0007121 bipolar cellular bud site selection(GO:0007121)
0.0 0.1 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.0 0.0 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.1 GO:0051647 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023) nucleus localization(GO:0051647)
0.0 0.1 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.0 0.0 GO:0031292 gene conversion at mating-type locus, DNA double-strand break processing(GO:0031292)
0.0 0.2 GO:0001302 replicative cell aging(GO:0001302)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.1 GO:0070545 PeBoW complex(GO:0070545)
0.9 3.7 GO:0032160 septin filament array(GO:0032160)
0.8 2.4 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.7 3.6 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.5 2.8 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.5 1.8 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.4 36.7 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.4 1.3 GO:0030428 cell septum(GO:0030428)
0.4 7.1 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.4 1.3 GO:0071261 Ssh1 translocon complex(GO:0071261)
0.4 1.6 GO:0005797 Golgi medial cisterna(GO:0005797)
0.4 1.6 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.4 24.5 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.3 1.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.3 1.3 GO:0031518 CBF3 complex(GO:0031518)
0.3 2.6 GO:0042597 periplasmic space(GO:0042597)
0.3 1.0 GO:0000229 cytoplasmic chromosome(GO:0000229) mitochondrial chromosome(GO:0000262)
0.3 4.5 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.3 3.2 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.3 1.3 GO:0000938 GARP complex(GO:0000938)
0.3 0.9 GO:0043529 GET complex(GO:0043529)
0.3 1.2 GO:0033254 vacuolar transporter chaperone complex(GO:0033254)
0.3 1.4 GO:0030689 Noc complex(GO:0030689)
0.3 1.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.3 1.0 GO:0000444 MIS12/MIND type complex(GO:0000444) nuclear MIS12/MIND complex(GO:0000818)
0.3 4.4 GO:0022626 cytosolic ribosome(GO:0022626)
0.2 2.0 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.2 1.7 GO:0005880 nuclear microtubule(GO:0005880)
0.2 1.0 GO:0033597 mitotic checkpoint complex(GO:0033597)
0.2 0.7 GO:0034457 Mpp10 complex(GO:0034457)
0.2 0.7 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.2 1.6 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.2 1.1 GO:0005663 DNA replication factor C complex(GO:0005663) Elg1 RFC-like complex(GO:0031391)
0.2 1.1 GO:0000144 cellular bud neck septin ring(GO:0000144)
0.2 0.6 GO:0008275 gamma-tubulin small complex, spindle pole body(GO:0000928) gamma-tubulin complex(GO:0000930) gamma-tubulin small complex(GO:0008275)
0.2 1.5 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.2 1.7 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.2 1.2 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.2 0.8 GO:0005946 alpha,alpha-trehalose-phosphate synthase complex (UDP-forming)(GO:0005946)
0.2 3.4 GO:0016586 RSC complex(GO:0016586)
0.2 0.9 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.2 1.5 GO:0033101 cellular bud membrane(GO:0033101)
0.2 1.1 GO:0032126 eisosome(GO:0032126)
0.2 1.3 GO:0032432 actin filament bundle(GO:0032432)
0.2 1.3 GO:0072686 mitotic spindle(GO:0072686)
0.2 0.7 GO:0000815 ESCRT III complex(GO:0000815)
0.2 0.5 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.2 1.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.2 1.9 GO:0034399 nuclear periphery(GO:0034399)
0.2 6.1 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.2 0.5 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.1 0.6 GO:0031502 dolichyl-phosphate-mannose-protein mannosyltransferase complex(GO:0031502)
0.1 0.4 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 9.7 GO:0005576 extracellular region(GO:0005576)
0.1 0.9 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.1 0.9 GO:0034455 t-UTP complex(GO:0034455)
0.1 1.6 GO:0005637 nuclear inner membrane(GO:0005637)
0.1 0.8 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 0.5 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 1.8 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 0.6 GO:0030478 actin cap(GO:0030478)
0.1 0.3 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1 0.7 GO:0030131 clathrin adaptor complex(GO:0030131)
0.1 0.3 GO:0035649 Nrd1 complex(GO:0035649)
0.1 0.3 GO:0070985 TFIIK complex(GO:0070985)
0.1 3.6 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.1 0.5 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.1 0.4 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.1 0.2 GO:0030869 RENT complex(GO:0030869)
0.1 0.5 GO:0000399 cellular bud neck septin structure(GO:0000399) cleavage apparatus septin structure(GO:0032161)
0.1 0.8 GO:0005720 nuclear heterochromatin(GO:0005720) nuclear telomeric heterochromatin(GO:0005724) telomeric heterochromatin(GO:0031933)
0.1 0.6 GO:0070772 PAS complex(GO:0070772)
0.1 0.2 GO:0030118 clathrin coat(GO:0030118)
0.1 0.6 GO:0034456 UTP-C complex(GO:0034456)
0.1 0.3 GO:0005825 half bridge of spindle pole body(GO:0005825)
0.1 0.4 GO:0005884 actin filament(GO:0005884)
0.1 0.4 GO:0000811 GINS complex(GO:0000811)
0.1 14.4 GO:0005933 cellular bud(GO:0005933)
0.1 0.8 GO:0030137 COPI-coated vesicle(GO:0030137)
0.1 2.1 GO:0005844 polysome(GO:0005844)
0.1 0.2 GO:0031417 NatC complex(GO:0031417)
0.1 0.6 GO:0005688 U6 snRNP(GO:0005688)
0.1 0.7 GO:0030681 nucleolar ribonuclease P complex(GO:0005655) multimeric ribonuclease P complex(GO:0030681)
0.1 0.2 GO:0005801 cis-Golgi network(GO:0005801)
0.1 10.0 GO:0005730 nucleolus(GO:0005730)
0.1 1.2 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.1 0.3 GO:0051233 spindle midzone(GO:0051233)
0.1 0.5 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
0.1 0.8 GO:0000786 nucleosome(GO:0000786)
0.1 0.2 GO:0005845 mRNA cap binding complex(GO:0005845)
0.1 0.5 GO:0030008 TRAPP complex(GO:0030008)
0.1 0.5 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 0.2 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 0.5 GO:0017119 Golgi transport complex(GO:0017119)
0.1 2.3 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.1 0.1 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 0.5 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.1 0.3 GO:0031501 alpha-1,6-mannosyltransferase complex(GO:0000136) mannosyltransferase complex(GO:0031501)
0.0 0.1 GO:0042729 DASH complex(GO:0042729)
0.0 0.1 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.2 GO:0034044 exomer complex(GO:0034044)
0.0 1.7 GO:0005811 lipid particle(GO:0005811)
0.0 0.1 GO:0044453 nuclear membrane part(GO:0044453)
0.0 1.4 GO:0005874 microtubule(GO:0005874)
0.0 0.1 GO:0005823 central plaque of spindle pole body(GO:0005823)
0.0 1.1 GO:0005816 microtubule organizing center(GO:0005815) spindle pole body(GO:0005816)
0.0 0.2 GO:0098827 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.0 0.2 GO:0008623 CHRAC(GO:0008623)
0.0 0.2 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.2 GO:0044611 nuclear pore inner ring(GO:0044611)
0.0 0.7 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 1.1 GO:0031410 cytoplasmic, membrane-bounded vesicle(GO:0016023) cytoplasmic vesicle(GO:0031410) membrane-bounded vesicle(GO:0031988) intracellular vesicle(GO:0097708)
0.0 0.3 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.1 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.1 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.4 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.8 GO:0071010 U2-type prespliceosome(GO:0071004) prespliceosome(GO:0071010)
0.0 0.2 GO:0044815 DNA packaging complex(GO:0044815)
0.0 2.8 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.1 GO:0000813 ESCRT I complex(GO:0000813)
0.0 4.3 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 0.1 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.1 GO:0015630 microtubule cytoskeleton(GO:0015630)
0.0 0.1 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.0 0.1 GO:0055087 Ski complex(GO:0055087)
0.0 0.1 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.1 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.0 0.1 GO:0048188 histone methyltransferase complex(GO:0035097) Set1C/COMPASS complex(GO:0048188)
0.0 0.1 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220) proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 1.3 GO:0005840 ribosome(GO:0005840)
0.0 0.0 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.1 GO:0000974 Prp19 complex(GO:0000974)
0.0 0.1 GO:0000798 nuclear cohesin complex(GO:0000798) cohesin complex(GO:0008278)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 9.7 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
1.0 4.0 GO:0016841 ammonia-lyase activity(GO:0016841)
0.9 2.7 GO:0015114 phosphate ion transmembrane transporter activity(GO:0015114)
0.9 3.4 GO:0000297 spermine transmembrane transporter activity(GO:0000297)
0.7 4.0 GO:0005354 galactose transmembrane transporter activity(GO:0005354)
0.6 1.9 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.6 1.8 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.6 2.4 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.6 2.3 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.6 3.4 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.5 3.3 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.5 1.6 GO:0070568 guanylyltransferase activity(GO:0070568)
0.5 0.5 GO:0015248 sterol transporter activity(GO:0015248)
0.5 1.4 GO:0004690 cyclic nucleotide-dependent protein kinase activity(GO:0004690) cAMP-dependent protein kinase activity(GO:0004691)
0.5 2.3 GO:0004707 MAP kinase activity(GO:0004707)
0.5 3.3 GO:0005496 steroid binding(GO:0005496) sterol binding(GO:0032934)
0.5 1.8 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups(GO:0016725) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.4 11.5 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.4 1.3 GO:0016872 intramolecular lyase activity(GO:0016872)
0.4 3.8 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.4 1.7 GO:0004622 lysophospholipase activity(GO:0004622)
0.4 1.2 GO:0004100 chitin synthase activity(GO:0004100)
0.4 1.6 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.4 1.2 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.4 1.2 GO:0051219 phosphoprotein binding(GO:0051219)
0.4 3.8 GO:0001133 RNA polymerase II transcription factor activity, sequence-specific transcription regulatory region DNA binding(GO:0001133)
0.4 3.8 GO:0031490 chromatin DNA binding(GO:0031490)
0.4 1.1 GO:0004619 phosphoglycerate mutase activity(GO:0004619)
0.4 1.1 GO:0015166 polyol transmembrane transporter activity(GO:0015166)
0.3 1.4 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.3 1.0 GO:0008251 adenosine deaminase activity(GO:0004000) tRNA-specific adenosine deaminase activity(GO:0008251)
0.3 0.7 GO:0019842 vitamin binding(GO:0019842)
0.3 1.0 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.3 4.5 GO:0001054 RNA polymerase I activity(GO:0001054)
0.3 3.2 GO:0001056 RNA polymerase III activity(GO:0001056)
0.3 14.5 GO:0019843 rRNA binding(GO:0019843)
0.3 1.2 GO:0016417 S-acyltransferase activity(GO:0016417)
0.3 1.4 GO:0008312 7S RNA binding(GO:0008312)
0.3 0.9 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.3 6.3 GO:0015926 glucosidase activity(GO:0015926)
0.3 1.4 GO:0008525 phosphatidylcholine transporter activity(GO:0008525) phosphatidylinositol transporter activity(GO:0008526)
0.3 1.6 GO:0003993 acid phosphatase activity(GO:0003993)
0.3 46.9 GO:0003735 structural constituent of ribosome(GO:0003735)
0.3 0.8 GO:0004497 monooxygenase activity(GO:0004497)
0.3 0.8 GO:0004805 trehalose-phosphatase activity(GO:0004805)
0.2 4.4 GO:0042162 telomeric DNA binding(GO:0042162)
0.2 0.7 GO:0001179 RNA polymerase I transcription factor binding(GO:0001179)
0.2 0.7 GO:0031370 eukaryotic initiation factor 4G binding(GO:0031370)
0.2 1.9 GO:1901681 sulfur compound binding(GO:1901681)
0.2 0.7 GO:0019003 GDP binding(GO:0019003)
0.2 1.1 GO:0008536 Ran GTPase binding(GO:0008536)
0.2 0.6 GO:0015116 secondary active sulfate transmembrane transporter activity(GO:0008271) sulfate transmembrane transporter activity(GO:0015116)
0.2 1.0 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.2 1.2 GO:0003725 double-stranded RNA binding(GO:0003725)
0.2 1.0 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.2 1.5 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.2 2.4 GO:0070491 repressing transcription factor binding(GO:0070491)
0.2 1.1 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.2 1.3 GO:0019237 centromeric DNA binding(GO:0019237)
0.2 0.9 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.2 1.4 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.2 0.7 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.2 3.1 GO:0004520 endodeoxyribonuclease activity(GO:0004520)
0.2 0.7 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.2 0.5 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.2 0.7 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.2 3.2 GO:0005048 signal sequence binding(GO:0005048)
0.2 4.8 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.2 2.6 GO:0015616 DNA translocase activity(GO:0015616)
0.2 0.5 GO:0009922 fatty acid elongase activity(GO:0009922)
0.2 0.5 GO:0015440 peptide-transporting ATPase activity(GO:0015440)
0.2 1.6 GO:0030276 clathrin binding(GO:0030276)
0.2 0.8 GO:0070546 L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.1 0.6 GO:0004771 sterol esterase activity(GO:0004771)
0.1 0.4 GO:0015088 copper uptake transmembrane transporter activity(GO:0015088)
0.1 0.3 GO:0072341 modified amino acid binding(GO:0072341)
0.1 0.9 GO:0019238 cyclohydrolase activity(GO:0019238)
0.1 0.4 GO:0042910 xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.1 0.5 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.1 0.8 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 0.4 GO:0019901 protein kinase binding(GO:0019901)
0.1 1.2 GO:0019904 protein domain specific binding(GO:0019904)
0.1 4.1 GO:0003743 translation initiation factor activity(GO:0003743)
0.1 1.6 GO:0051015 actin filament binding(GO:0051015)
0.1 7.5 GO:0003924 GTPase activity(GO:0003924)
0.1 0.4 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.1 1.0 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.1 0.4 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.1 0.4 GO:0005262 calcium channel activity(GO:0005262)
0.1 0.6 GO:0017048 Rho GTPase binding(GO:0017048)
0.1 0.3 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.1 1.3 GO:0019887 protein kinase regulator activity(GO:0019887)
0.1 3.8 GO:0003724 RNA helicase activity(GO:0003724)
0.1 0.3 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 1.7 GO:0030515 snoRNA binding(GO:0030515)
0.1 0.4 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.1 1.3 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.1 0.5 GO:0019201 nucleotide kinase activity(GO:0019201)
0.1 1.4 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 0.1 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.1 0.7 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668)
0.1 0.7 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1 0.4 GO:0005338 nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.1 1.2 GO:0001671 ATPase activator activity(GO:0001671)
0.1 2.5 GO:0015631 tubulin binding(GO:0015631)
0.1 0.9 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.1 1.2 GO:0008483 transaminase activity(GO:0008483) transferase activity, transferring nitrogenous groups(GO:0016769)
0.1 1.3 GO:0019001 GTP binding(GO:0005525) guanyl nucleotide binding(GO:0019001) guanyl ribonucleotide binding(GO:0032561)
0.1 0.3 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 1.7 GO:0051536 iron-sulfur cluster binding(GO:0051536) metal cluster binding(GO:0051540)
0.1 0.8 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 0.4 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.1 0.3 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661)
0.1 1.1 GO:0003714 transcription corepressor activity(GO:0003714)
0.1 0.5 GO:0019239 deaminase activity(GO:0019239)
0.1 0.2 GO:0016882 cyclo-ligase activity(GO:0016882)
0.1 0.8 GO:0042803 protein homodimerization activity(GO:0042803)
0.1 2.5 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.1 1.6 GO:0008170 N-methyltransferase activity(GO:0008170)
0.1 0.9 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.1 0.7 GO:0004526 ribonuclease MRP activity(GO:0000171) ribonuclease P activity(GO:0004526)
0.1 0.3 GO:0015103 inorganic anion transmembrane transporter activity(GO:0015103)
0.1 0.5 GO:0004579 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 0.2 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.1 0.2 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.1 0.3 GO:0008135 translation factor activity, RNA binding(GO:0008135)
0.1 0.5 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 0.2 GO:0036002 pre-mRNA binding(GO:0036002)
0.1 2.6 GO:0030695 GTPase regulator activity(GO:0030695)
0.1 1.8 GO:0030674 protein binding, bridging(GO:0030674)
0.1 0.2 GO:0070336 flap-structured DNA binding(GO:0070336)
0.1 0.2 GO:0003680 AT DNA binding(GO:0003680)
0.1 0.1 GO:0016840 carbon-nitrogen lyase activity(GO:0016840)
0.1 0.2 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.1 0.2 GO:0015230 FAD transmembrane transporter activity(GO:0015230)
0.1 0.3 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033) alcohol dehydrogenase (NADP+) activity(GO:0008106)
0.1 0.3 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 0.5 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.1 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.8 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553)
0.0 0.2 GO:0008242 omega peptidase activity(GO:0008242)
0.0 2.1 GO:0008565 protein transporter activity(GO:0008565)
0.0 1.4 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.3 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 0.4 GO:0000009 alpha-1,6-mannosyltransferase activity(GO:0000009)
0.0 0.4 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755) cis-trans isomerase activity(GO:0016859)
0.0 0.2 GO:0042124 glucanosyltransferase activity(GO:0042123) 1,3-beta-glucanosyltransferase activity(GO:0042124)
0.0 0.1 GO:0019900 kinase binding(GO:0019900)
0.0 1.1 GO:0008092 cytoskeletal protein binding(GO:0008092)
0.0 0.2 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.8 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.1 GO:0016531 copper chaperone activity(GO:0016531)
0.0 0.3 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.9 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.7 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.1 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.0 0.8 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.1 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 0.1 GO:0004312 fatty acid synthase activity(GO:0004312)
0.0 0.3 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 0.4 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.0 0.3 GO:0050661 NADP binding(GO:0050661)
0.0 0.1 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 0.1 GO:0051183 vitamin transporter activity(GO:0051183)
0.0 0.1 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670) oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671) thiol oxidase activity(GO:0016972)
0.0 0.1 GO:0004702 receptor signaling protein serine/threonine kinase activity(GO:0004702)
0.0 0.1 GO:0008252 nucleotidase activity(GO:0008252)
0.0 0.6 GO:0016876 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 0.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.0 GO:0019207 kinase regulator activity(GO:0019207)
0.0 0.5 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.0 0.1 GO:0015662 ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism(GO:0015662)
0.0 0.2 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.1 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.1 GO:0000049 tRNA binding(GO:0000049)
0.0 0.0 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.1 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983) transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.3 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 0.0 GO:0008762 UDP-N-acetylmuramate dehydrogenase activity(GO:0008762)
0.0 0.2 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.1 GO:0051087 chaperone binding(GO:0051087)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.5 0.5 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.3 1.2 PID E2F PATHWAY E2F transcription factor network
0.3 1.5 PID FGF PATHWAY FGF signaling pathway
0.2 1.1 PID P73PATHWAY p73 transcription factor network
0.2 0.5 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.2 0.5 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 0.4 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 1.1 PID ATR PATHWAY ATR signaling pathway
0.1 0.4 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.1 0.1 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.1 0.2 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 0.1 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 0.1 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.0 PID ERBB4 PATHWAY ErbB4 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 4.0 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.4 1.3 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.4 6.5 REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION Genes involved in 3' -UTR-mediated translational regulation
0.4 2.3 REACTOME TRANSLATION Genes involved in Translation
0.4 0.8 REACTOME G1 PHASE Genes involved in G1 Phase
0.3 1.0 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.3 1.1 REACTOME NUCLEOTIDE EXCISION REPAIR Genes involved in Nucleotide Excision Repair
0.2 0.6 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.2 1.3 REACTOME GPCR DOWNSTREAM SIGNALING Genes involved in GPCR downstream signaling
0.2 0.4 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.2 0.5 REACTOME SIGNALLING TO ERKS Genes involved in Signalling to ERKs
0.2 0.7 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.2 0.7 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.2 1.0 REACTOME REGULATION OF MITOTIC CELL CYCLE Genes involved in Regulation of mitotic cell cycle
0.2 0.5 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.1 1.0 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 0.6 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 0.2 REACTOME SLC MEDIATED TRANSMEMBRANE TRANSPORT Genes involved in SLC-mediated transmembrane transport
0.1 0.2 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 0.4 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.1 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.1 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.3 REACTOME LATE PHASE OF HIV LIFE CYCLE Genes involved in Late Phase of HIV Life Cycle
0.0 0.0 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling