Results for DAL82
Z-value: 0.77
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Transcription factors associated with DAL82
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
DAL82
|
S000005258 | Positive regulator of allophanate inducible genes |
Activity-expression correlation:
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| YGR108W Show fit | 4.39 |
B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the transition from G2 to M phase; accumulates during G2 and M, then targeted via a destruction box motif for ubiquitin-mediated degradation by the proteasome |
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| YJR094W-A Show fit | 4.21 |
Protein component of the large (60S) ribosomal subunit, identical to Rpl43Ap and has similarity to rat L37a ribosomal protein |
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| YJL153C Show fit | 4.15 |
Inositol 1-phosphate synthase, involved in synthesis of inositol phosphates and inositol-containing phospholipids; transcription is coregulated with other phospholipid biosynthetic genes by Ino2p and Ino4p, which bind the UASINO DNA element |
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| YOL086C Show fit | 3.45 |
Alcohol dehydrogenase, fermentative isozyme active as homo- or heterotetramers; required for the reduction of acetaldehyde to ethanol, the last step in the glycolytic pathway |
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| YPL250W-A Show fit | 3.36 |
Identified by fungal homology and RT-PCR |
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| YNR016C Show fit | 3.31 |
Acetyl-CoA carboxylase, biotin containing enzyme that catalyzes the carboxylation of acetyl-CoA to form malonyl-CoA; required for de novo biosynthesis of long-chain fatty acids |
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| YOR376W-A Show fit | 2.89 |
Putative protein of unknown function; identified by fungal homology and RT-PCR |
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| YLR167W Show fit | 2.80 |
Fusion protein that is cleaved to yield a ribosomal protein of the small (40S) subunit and ubiquitin; ubiquitin may facilitate assembly of the ribosomal protein into ribosomes; interacts genetically with translation factor eIF2B |
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| YLR388W Show fit | 2.79 |
Protein component of the small (40S) ribosomal subunit; nearly identical to Rps29Bp and has similarity to rat S29 and E. coli S14 ribosomal proteins |
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| YGL123C-A Show fit | 2.72 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps the verified gene RPS2/YGL123W |
Network of associatons between targets according to the STRING database.
First level regulatory network of DAL82
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 57.3 | GO:0002181 | cytoplasmic translation(GO:0002181) |
| 0.6 | 10.9 | GO:0051029 | rRNA export from nucleus(GO:0006407) rRNA transport(GO:0051029) |
| 0.4 | 9.5 | GO:0006334 | nucleosome assembly(GO:0006334) |
| 1.3 | 6.4 | GO:0001676 | long-chain fatty acid metabolic process(GO:0001676) |
| 0.6 | 6.1 | GO:0006116 | NADH oxidation(GO:0006116) |
| 0.6 | 3.9 | GO:0010696 | positive regulation of spindle pole body separation(GO:0010696) |
| 0.6 | 3.8 | GO:0006021 | inositol biosynthetic process(GO:0006021) |
| 0.2 | 3.6 | GO:0009304 | tRNA transcription(GO:0009304) tRNA transcription from RNA polymerase III promoter(GO:0042797) |
| 0.2 | 3.4 | GO:1904029 | regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029) |
| 0.1 | 3.3 | GO:0006696 | ergosterol biosynthetic process(GO:0006696) phytosteroid biosynthetic process(GO:0016129) cellular alcohol biosynthetic process(GO:0044108) cellular lipid biosynthetic process(GO:0097384) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 37.1 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.5 | 31.2 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 0.0 | 14.3 | GO:0005783 | endoplasmic reticulum(GO:0005783) |
| 0.8 | 9.4 | GO:0000788 | nuclear nucleosome(GO:0000788) |
| 0.4 | 6.3 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
| 0.0 | 3.8 | GO:0030684 | preribosome(GO:0030684) |
| 0.2 | 3.6 | GO:0005666 | DNA-directed RNA polymerase III complex(GO:0005666) |
| 0.1 | 3.4 | GO:0005887 | integral component of plasma membrane(GO:0005887) |
| 0.0 | 3.4 | GO:0005933 | cellular bud(GO:0005933) |
| 0.1 | 3.2 | GO:0042645 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 56.7 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 0.3 | 9.8 | GO:0046982 | protein heterodimerization activity(GO:0046982) |
| 0.4 | 9.4 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
| 0.9 | 5.5 | GO:0004022 | alcohol dehydrogenase (NAD) activity(GO:0004022) |
| 0.4 | 4.5 | GO:0031386 | protein tag(GO:0031386) |
| 1.4 | 4.2 | GO:0016872 | intramolecular lyase activity(GO:0016872) |
| 0.2 | 3.6 | GO:0001056 | RNA polymerase III activity(GO:0001056) |
| 0.2 | 3.1 | GO:0015926 | glucosidase activity(GO:0015926) |
| 0.5 | 3.0 | GO:0016846 | carbon-sulfur lyase activity(GO:0016846) |
| 0.0 | 3.0 | GO:0003924 | GTPase activity(GO:0003924) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 1.3 | PID SHP2 PATHWAY | SHP2 signaling |
| 0.1 | 1.1 | PID FANCONI PATHWAY | Fanconi anemia pathway |
| 0.1 | 0.9 | NABA SECRETED FACTORS | Genes encoding secreted soluble factors |
| 0.3 | 0.8 | PID FGF PATHWAY | FGF signaling pathway |
| 0.2 | 0.5 | PID HIF1 TFPATHWAY | HIF-1-alpha transcription factor network |
| 0.1 | 0.4 | PID UPA UPAR PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
| 0.1 | 0.3 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.1 | 0.2 | PID INTEGRIN A4B1 PATHWAY | Alpha4 beta1 integrin signaling events |
| 0.0 | 0.2 | PID PLK1 PATHWAY | PLK1 signaling events |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.9 | 7.2 | REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S | Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S |
| 0.4 | 7.2 | REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION | Genes involved in Influenza Viral RNA Transcription and Replication |
| 0.3 | 1.6 | REACTOME TRANSLATION | Genes involved in Translation |
| 0.2 | 1.5 | REACTOME SIGNALING BY GPCR | Genes involved in Signaling by GPCR |
| 0.5 | 1.4 | REACTOME SULFUR AMINO ACID METABOLISM | Genes involved in Sulfur amino acid metabolism |
| 0.4 | 1.3 | REACTOME SIGNALING BY FGFR IN DISEASE | Genes involved in Signaling by FGFR in disease |
| 0.3 | 1.3 | REACTOME TRANSCRIPTION COUPLED NER TC NER | Genes involved in Transcription-coupled NER (TC-NER) |
| 0.1 | 1.0 | REACTOME DEADENYLATION DEPENDENT MRNA DECAY | Genes involved in Deadenylation-dependent mRNA decay |
| 0.1 | 0.6 | REACTOME GLYCOLYSIS | Genes involved in Glycolysis |
| 0.1 | 0.6 | REACTOME FATTY ACID TRIACYLGLYCEROL AND KETONE BODY METABOLISM | Genes involved in Fatty acid, triacylglycerol, and ketone body metabolism |