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Results for DAL80

Z-value: 0.54

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Transcription factors associated with DAL80

Gene Symbol Gene ID Gene Info
DAL80
S000001742 Negative regulator of genes in multiple nitrogen degradation pathways

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
DAL80YKR034W-0.183.7e-01Click!

Activity profile of DAL80 motif

Sorted Z-values of DAL80 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
YKR038C 5.18
KAE1
Putative glycoprotease proposed to be in transcription as a component of the EKC protein complex with Bud32p, Cgi121p, Pcc1p, and Gon7p; also identified as a component of the KEOPS protein complex
YDL211C 4.92 Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole
YKR092C 4.60
SRP40
Nucleolar, serine-rich protein with a role in preribosome assembly or transport; may function as a chaperone of small nucleolar ribonucleoprotein particles (snoRNPs); immunologically and structurally to rat Nopp140
YKR039W 4.39
GAP1
General amino acid permease; localization to the plasma membrane is regulated by nitrogen source
YOR315W 3.20
SFG1
Nuclear protein, putative transcription factor required for growth of superficial pseudohyphae (which do not invade the agar substrate) but not for invasive pseudohyphal growth; may act together with Phd1p; potential Cdc28p substrate
YJR094W-A 3.01
RPL43B
Protein component of the large (60S) ribosomal subunit, identical to Rpl43Ap and has similarity to rat L37a ribosomal protein
YDR041W 2.95
RSM10
Mitochondrial ribosomal protein of the small subunit, has similarity to E. coli S10 ribosomal protein; essential for viability, unlike most other mitoribosomal proteins
YOL127W 2.90
RPL25
Primary rRNA-binding ribosomal protein component of the large (60S) ribosomal subunit, has similarity to E. coli L23 and rat L23a ribosomal proteins; binds to 26S rRNA via a conserved C-terminal motif
YDR040C 2.58
ENA1
P-type ATPase sodium pump, involved in Na+ and Li+ efflux to allow salt tolerance
YPR169W-A 2.51 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps two other dubious ORFs: YPR170C and YPR170W-B
YIR021W 2.46
MRS1
Protein required for the splicing of two mitochondrial group I introns (BI3 in COB and AI5beta in COX1); forms a splicing complex, containing four subunits of Mrs1p and two subunits of the BI3-encoded maturase, that binds to the BI3 RNA
YIL118W 2.41
RHO3
Non-essential small GTPase of the Rho/Rac subfamily of Ras-like proteins involved in the establishment of cell polarity; GTPase activity positively regulated by the GTPase activating protein (GAP) Rgd1p
YFL022C 2.37
FRS2
Alpha subunit of cytoplasmic phenylalanyl-tRNA synthetase, forms a tetramer with Frs1p to form active enzyme; evolutionarily distant from mitochondrial phenylalanyl-tRNA synthetase based on protein sequence, but substrate binding is similar
YLR154C 2.34
RNH203
Ribonuclease H2 subunit, required for RNase H2 activity
YOR376W-A 2.31 Putative protein of unknown function; identified by fungal homology and RT-PCR
YOR375C 1.98
GDH1
NADP(+)-dependent glutamate dehydrogenase, synthesizes glutamate from ammonia and alpha-ketoglutarate; rate of alpha-ketoglutarate utilization differs from Gdh3p; expression regulated by nitrogen and carbon sources
YDR002W 1.83
YRB1
Ran GTPase binding protein; involved in nuclear protein import and RNA export, ubiquitin-mediated protein degradation during the cell cycle; shuttles between the nucleus and cytoplasm; is essential; homolog of human RanBP1
YFR055W 1.83
IRC7
Putative cystathionine beta-lyase; involved in copper ion homeostasis and sulfur metabolism; null mutant displays increased levels of spontaneous Rad52p foci; expression induced by nitrogen limitation in a GLN3, GAT1-dependent manner
YER001W 1.82
MNN1
Alpha-1,3-mannosyltransferase, integral membrane glycoprotein of the Golgi complex, required for addition of alpha1,3-mannose linkages to N-linked and O-linked oligosaccharides, one of five S. cerevisiae proteins of the MNN1 family
YPR170W-A 1.80 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data; identified by expression profiling and mass spectrometry
YFR056C 1.78 Dubious open reading frame unlikely to encode a protein based on available experimental and comparative sequence data; partially overlaps the uncharacterized gene YFR055W
YPR171W 1.64
BSP1
Adapter that links synaptojanins Inp52p and Inp53p to the cortical actin cytoskeleton
YJR094C 1.57
IME1
Master regulator of meiosis that is active only during meiotic events, activates transcription of early meiotic genes through interaction with Ume6p, degraded by the 26S proteasome following phosphorylation by Ime2p
YOR313C 1.55
SPS4
Protein whose expression is induced during sporulation; not required for sporulation; heterologous expression in E. coli induces the SOS response that senses DNA damage
YPR119W 1.53
CLB2
B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the transition from G2 to M phase; accumulates during G2 and M, then targeted via a destruction box motif for ubiquitin-mediated degradation by the proteasome
YLR154W-A 1.50 Dubious open reading frame unlikely to encode a protein; encoded within the the 25S rRNA gene on the opposite strand
YLR154W-B 1.47 Dubious open reading frame unlikely to encode a protein; encoded within the the 25S rRNA gene on the opposite strand
YIR033W 1.41
MGA2
ER membrane protein involved in regulation of OLE1 transcription, acts with homolog Spt23p; inactive ER form dimerizes and one subunit is then activated by ubiquitin/proteasome-dependent processing followed by nuclear targeting
YOR096W 1.40
RPS7A
Protein component of the small (40S) ribosomal subunit, nearly identical to Rps7Bp; interacts with Kti11p; deletion causes hypersensitivity to zymocin; has similarity to rat S7 and Xenopus S8 ribosomal proteins
YPL177C 1.39
CUP9
Homeodomain-containing transcriptional repressor of PTR2, which encodes a major peptide transporter; imported peptides activate ubiquitin-dependent proteolysis, resulting in degradation of Cup9p and de-repression of PTR2 transcription
YGL031C 1.38
RPL24A
Ribosomal protein L30 of the large (60S) ribosomal subunit, nearly identical to Rpl24Bp and has similarity to rat L24 ribosomal protein; not essential for translation but may be required for normal translation rate
YLR413W 1.38 Putative protein of unknown function; YLR413W is not an essential gene
YKR093W 1.37
PTR2
Integral membrane peptide transporter, mediates transport of di- and tri-peptides; conserved protein that contains 12 transmembrane domains; PTR2 expression is regulated by the N-end rule pathway via repression by Cup9p
YPR170C 1.37 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the dubious ORFs YPR169W-A and YPR170W-B
YCR099C 1.36 Putative protein of unknown function
YOL019W 1.35 Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery and vacuole
YGR060W 1.33
ERG25
C-4 methyl sterol oxidase, catalyzes the first of three steps required to remove two C-4 methyl groups from an intermediate in ergosterol biosynthesis; mutants accumulate the sterol intermediate 4,4-dimethylzymosterol
YDR098C 1.31
GRX3
Hydroperoxide and superoxide-radical responsive glutathione-dependent oxidoreductase; monothiol glutaredoxin subfamily member along with Grx4p and Grx5p; protects cells from oxidative damage
YNR001W-A 1.28 Dubious open reading frame unlikely to encode a functional protein; identified by homology
YOR008C-A 1.28 Putative protein of unknown function, includes a potential transmembrane domain; deletion results in slightly lengthened telomeres
YGR264C 1.23
MES1
Methionyl-tRNA synthetase, forms a complex with glutamyl-tRNA synthetase (Gus1p) and Arc1p, which increases the catalytic efficiency of both tRNA synthetases; also has a role in nuclear export of tRNAs
YGR265W 1.22 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF MES1/YGR264C, which encodes methionyl-tRNA synthetase
YIL119C 1.19
RPI1
Putative transcriptional regulator; overexpression suppresses the heat shock sensitivity of wild-type RAS2 overexpression and also suppresses the cell lysis defect of an mpk1 mutation
YJL173C 1.17
RFA3
Subunit of heterotrimeric Replication Protein A (RPA), which is a highly conserved single-stranded DNA binding protein involved in DNA replication, repair, and recombination
YKL182W 1.16
FAS1
Beta subunit of fatty acid synthetase, which catalyzes the synthesis of long-chain saturated fatty acids; contains acetyltransacylase, dehydratase, enoyl reductase, malonyl transacylase, and palmitoyl transacylase activities
YPL037C 1.16
EGD1
Subunit beta1 of the nascent polypeptide-associated complex (NAC) involved in protein targeting, associated with cytoplasmic ribosomes; enhances DNA binding of the Gal4p activator; homolog of human BTF3b
YKL096W-A 1.13
CWP2
Covalently linked cell wall mannoprotein, major constituent of the cell wall; plays a role in stabilizing the cell wall; involved in low pH resistance; precursor is GPI-anchored
YIL164C 1.12
NIT1
Nitrilase, member of the nitrilase branch of the nitrilase superfamily; in closely related species and other S. cerevisiae strain backgrounds YIL164C and adjacent ORF, YIL165C, likely constitute a single ORF encoding a nitrilase gene
YLR154W-C 1.10
TAR1
Mitochondrial protein of unknown function, overexpression suppresses an rpo41 mutation affecting mitochondrial RNA polymerase; encoded within the 25S rRNA gene on the opposite strand
YBL072C 1.09
RPS8A
Protein component of the small (40S) ribosomal subunit; identical to Rps8Bp and has similarity to rat S8 ribosomal protein
YGR040W 1.07
KSS1
Mitogen-activated protein kinase (MAPK) involved in signal transduction pathways that control filamentous growth and pheromone response; the KSS1 gene is nonfunctional in S288C strains and functional in W303 strains
YCL024W 1.04
KCC4
Protein kinase of the bud neck involved in the septin checkpoint, associates with septin proteins, negatively regulates Swe1p by phosphorylation, shows structural homology to bud neck kinases Gin4p and Hsl1p
YEL001C 1.02
IRC22
Putative protein of unknown function; green fluorescent protein (GFP)-fusion localizes to the ER; YEL001C is non-essential; null mutant displays increased levels of spontaneous Rad52p foci
YMR108W 1.02
ILV2
Acetolactate synthase, catalyses the first common step in isoleucine and valine biosynthesis and is the target of several classes of inhibitors, localizes to the mitochondria; expression of the gene is under general amino acid control
YKL063C 1.02 Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the Golgi
YGL030W 1.01
RPL30
Protein component of the large (60S) ribosomal subunit, has similarity to rat L30 ribosomal protein; involved in pre-rRNA processing in the nucleolus; autoregulates splicing of its transcript
YGR121W-A 1.01 Putative protein of unknown function
YEL062W 1.01
NPR2
Protein with a possible role in regulating expression of nitrogen permeases; transcription is induced in response to proline and urea; contains two PEST sequences; null mutant is resistant to cisplatin and doxorubicin
YCR018C 1.00
SRD1
Protein involved in the processing of pre-rRNA to mature rRNA; contains a C2/C2 zinc finger motif; srd1 mutation suppresses defects caused by the rrp1-1 mutation
YER137C 0.99 Putative protein of unknown function
YPR170W-B 0.99 Putative protein of unknown function, conserved in fungi; partially overlaps the dubious genes YPR169W-A, YPR170W-A and YRP170C
YHR201C 0.97
PPX1
Exopolyphosphatase, hydrolyzes inorganic polyphosphate (poly P) into Pi residues; located in the cytosol, plasma membrane, and mitochondrial matrix
YMR049C 0.97
ERB1
Protein required for maturation of the 25S and 5.8S ribosomal RNAs; constituent of 66S pre-ribosomal particles; homologous to mammalian Bop1
YOR314W 0.96 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
YJR105W 0.96
ADO1
Adenosine kinase, required for the utilization of S-adenosylmethionine (AdoMet); may be involved in recycling adenosine produced through the methyl cycle
YGR161C 0.95
RTS3
Putative component of the protein phosphatase type 2A complex
YBR210W 0.95
ERV15
Protein involved in export of proteins from the endoplasmic reticulum, has similarity to Erv14p
YLR257W 0.94 Putative protein of unknown function
YCL023C 0.93 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps verified ORF KCC4
YGL148W 0.92
ARO2
Bifunctional chorismate synthase and flavin reductase, catalyzes the conversion of 5-enolpyruvylshikimate 3-phosphate (EPSP) to form chorismate, which is a precursor to aromatic amino acids
YLR448W 0.91
RPL6B
Protein component of the large (60S) ribosomal subunit, has similarity to Rpl6Ap and to rat L6 ribosomal protein; binds to 5.8S rRNA
YDR044W 0.89
HEM13
Coproporphyrinogen III oxidase, an oxygen requiring enzyme that catalyzes the sixth step in the heme biosynthetic pathway; localizes to the mitochondrial inner membrane; transcription is repressed by oxygen and heme (via Rox1p and Hap1p)
YMR177W 0.88
MMT1
Putative metal transporter involved in mitochondrial iron accumulation; closely related to Mmt2p
YHL015W 0.87
RPS20
Protein component of the small (40S) ribosomal subunit; overproduction suppresses mutations affecting RNA polymerase III-dependent transcription; has similarity to E. coli S10 and rat S20 ribosomal proteins
YOR143C 0.86
THI80
Thiamine pyrophosphokinase, phosphorylates thiamine to produce the coenzyme thiamine pyrophosphate (thiamine diphosphate)
YHR208W 0.86
BAT1
Mitochondrial branched-chain amino acid aminotransferase, homolog of murine ECA39; highly expressed during logarithmic phase and repressed during stationary phase
YHR063C 0.85
PAN5
2-dehydropantoate 2-reductase, part of the pantothenic acid pathway, structurally homologous to E. coli panE
YOR028C 0.85
CIN5
Basic leucine zipper transcriptional factor of the yAP-1 family that mediates pleiotropic drug resistance and salt tolerance; localizes constitutively to the nucleus
YIR030W-A 0.84 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YBR232C 0.83 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
YDR037W 0.82
KRS1
Lysyl-tRNA synthetase; also identified as a negative regulator of general control of amino acid biosynthesis
YMR296C 0.81
LCB1
Component of serine palmitoyltransferase, responsible along with Lcb2p for the first committed step in sphingolipid synthesis, which is the condensation of serine with palmitoyl-CoA to form 3-ketosphinganine
YHR007C 0.80
ERG11
Lanosterol 14-alpha-demethylase, catalyzes the C-14 demethylation of lanosterol to form 4,4''-dimethyl cholesta-8,14,24-triene-3-beta-ol in the ergosterol biosynthesis pathway; member of the cytochrome P450 family
YIR031C 0.78
DAL7
Malate synthase, role in allantoin degradation unknown; expression sensitive to nitrogen catabolite repression and induced by allophanate, an intermediate in allantoin degradation
YKL110C 0.77
KTI12
Protein that plays a role, with Elongator complex, in modification of wobble nucleosides in tRNA; involved in sensitivity to G1 arrest induced by zymocin; interacts with chromatin throughout the genome; also interacts with Cdc19p
YDL213C 0.76
NOP6
Putative RNA-binding protein implicated in ribosome biogenesis; contains an RNA recognition motif (RRM) and has similarity to hydrophilins; NOP6 may be a fungal-specific gene as no homologs have been yet identified in higher eukaryotes
YDR089W 0.76 Protein of unknown function; deletion confers resistance to Nickel
YBR208C 0.76
DUR1,2
Urea amidolyase, contains both urea carboxylase and allophanate hydrolase activities, degrades urea to CO2 and NH3; expression sensitive to nitrogen catabolite repression and induced by allophanate, an intermediate in allantoin degradation
YNR013C 0.76
PHO91
Low-affinity phosphate transporter of the vacuolar membrane; deletion of pho84, pho87, pho89, pho90, and pho91 causes synthetic lethality; transcription independent of Pi and Pho4p activity; overexpression results in vigorous growth
YBR233W 0.75
PBP2
RNA binding protein with similarity to mammalian heterogeneous nuclear RNP K protein, involved in the regulation of telomere position effect and telomere length
YAR008W 0.75
SEN34
Subunit of the tRNA splicing endonuclease, which is composed of Sen2p, Sen15p, Sen34p, and Sen54p; Sen34p contains the active site for tRNA 3' splice site cleavage and has similarity to Sen2p and to Archaeal tRNA splicing endonuclease
YPR195C 0.75 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
YPL137C 0.75
GIP3
Glc7-interacting protein whose overexpression relocalizes Glc7p from the nucleus and prevents chromosome segregation; may interact with ribosomes, based on co-purification experiments
YKL218C 0.74
SRY1
3-hydroxyaspartate dehydratase, deaminates L-threo-3-hydroxyaspartate to form oxaloacetate and ammonia; required for survival in the presence of hydroxyaspartate
YGR155W 0.74
CYS4
Cystathionine beta-synthase, catalyzes the synthesis of cystathionine from serine and homocysteine, the first committed step in cysteine biosynthesis
YGR293C 0.72 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the uncharacterized ORF YGR294W
YMR083W 0.72
ADH3
Mitochondrial alcohol dehydrogenase isozyme III; involved in the shuttling of mitochondrial NADH to the cytosol under anaerobic conditions and ethanol production
YOL155C 0.72
HPF1
Haze-protective mannoprotein that reduces the particle size of aggregated proteins in white wines
YLR300W 0.71
EXG1
Major exo-1,3-beta-glucanase of the cell wall, involved in cell wall beta-glucan assembly; exists as three differentially glycosylated isoenzymes
YGL035C 0.71
MIG1
Transcription factor involved in glucose repression; sequence specific DNA binding protein containing two Cys2His2 zinc finger motifs; regulated by the SNF1 kinase and the GLC7 phosphatase
YOR029W 0.71 Dubious open reading frame unlikely to encode a functional protein; based on available experimental and comparative sequence data
YEL068C 0.71 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YNL113W 0.71
RPC19
RNA polymerase subunit, common to RNA polymerases I and III
YBR138C 0.70 Cytoplasmic protein of unknown function, potentially phosphorylated by Cdc28p; YBR138C is not an essential gene
YMR123W 0.70
PKR1
V-ATPase assembly factor, functions with other V-ATPase assembly factors in the ER to efficiently assemble the V-ATPase membrane sector (V0); overproduction confers resistance to Pichia farinosa killer toxin
YOR051C 0.69 Nuclear protein that inhibits replication of Brome mosaic virus in S. cerevisiae, which is a model system for studying replication of positive-strand RNA viruses in their natural hosts
YGL179C 0.69
TOS3
Protein kinase, related to and functionally redundant with Elm1p and Sak1p for the phosphorylation and activation of Snf1p; functionally orthologous to LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome
YOR030W 0.69
DFG16
Probable multiple transmembrane protein, involved in diploid invasive and pseudohyphal growth upon nitrogen starvation; required for accumulation of processed Rim101p
YIL169C 0.69 Putative protein of unknown function; serine/threonine rich and highly similar to YOL155C, a putative glucan alpha-1,4-glucosidase; transcript is induced in both high and low pH environments; YIL169C is a non-essential gene
YLR048W 0.68
RPS0B
Protein component of the small (40S) ribosomal subunit, nearly identical to Rps0Ap; required for maturation of 18S rRNA along with Rps0Ap; deletion of either RPS0 gene reduces growth rate, deletion of both genes is lethal
YER073W 0.68
ALD5
Mitochondrial aldehyde dehydrogenase, involved in regulation or biosynthesis of electron transport chain components and acetate formation; activated by K+; utilizes NADP+ as the preferred coenzyme; constitutively expressed
YPL055C 0.68
LGE1
Protein of unknown function; null mutant forms abnormally large cells, and homozygous diploid null mutant displays delayed premeiotic DNA synthesis and reduced efficiency of meiotic nuclear division
YKR075C 0.68 Protein of unknown function; similar to YOR062Cp and Reg1p; expression regulated by glucose and Rgt1p; GFP-fusion protein is induced in response to the DNA-damaging agent MMS
YHL028W 0.67
WSC4
ER membrane protein involved in the translocation of soluble secretory proteins and insertion of membrane proteins into the ER membrane; may also have a role in the stress response but has only partial functional overlap with WSC1-3
YAL033W 0.64
POP5
Subunit of both RNase MRP, which cleaves pre-rRNA, and nuclear RNase P, which cleaves tRNA precursors to generate mature 5' ends
YGR214W 0.64
RPS0A
Protein component of the small (40S) ribosomal subunit, nearly identical to Rps0Bp; required for maturation of 18S rRNA along with Rps0Bp; deletion of either RPS0 gene reduces growth rate, deletion of both genes is lethal
YKL062W 0.64
MSN4
Transcriptional activator related to Msn2p; activated in stress conditions, which results in translocation from the cytoplasm to the nucleus; binds DNA at stress response elements of responsive genes, inducing gene expression
YNL178W 0.64
RPS3
Protein component of the small (40S) ribosomal subunit, has apurinic/apyrimidinic (AP) endonuclease activity; essential for viability; has similarity to E. coli S3 and rat S3 ribosomal proteins
YGR294W 0.64
PAU12
Hypothetical protein
YDR279W 0.64
RNH202
Ribonuclease H2 subunit, required for RNase H2 activity
YBL077W 0.63 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene ILS1/YBL076C
YMR183C 0.63
SSO2
Plasma membrane t-SNARE involved in fusion of secretory vesicles at the plasma membrane; syntaxin homolog that is functionally redundant with Sso1p
YOR355W 0.63
GDS1
Protein of unknown function, required for growth on glycerol as a carbon source; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
YMR070W 0.62
MOT3
Nuclear transcription factor with two Cys2-His2 zinc fingers; involved in repression of a subset of hypoxic genes by Rox1p, repression of several DAN/TIR genes during aerobic growth, and repression of ergosterol biosynthetic genes
YMR106C 0.62
YKU80
Subunit of the telomeric Ku complex (Yku70p-Yku80p), involved in telomere length maintenance, structure and telomere position effect; relocates to sites of double-strand cleavage to promote nonhomologous end joining during DSB repair
YMR246W 0.62
FAA4
Long chain fatty acyl-CoA synthetase, regulates protein modification during growth in the presence of ethanol, functions to incorporate palmitic acid into phospholipids and neutral lipids
YDR417C 0.62 Hypothetical protein
YLR355C 0.61
ILV5
Acetohydroxyacid reductoisomerase, mitochondrial protein involved in branched-chain amino acid biosynthesis, also required for maintenance of wild-type mitochondrial DNA and found in mitochondrial nucleoids
YMR208W 0.60
ERG12
Mevalonate kinase, acts in the biosynthesis of isoprenoids and sterols, including ergosterol, from mevalonate
YHR063W-A 0.60 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YGL209W 0.59
MIG2
Protein containing zinc fingers, involved in repression, along with Mig1p, of SUC2 (invertase) expression by high levels of glucose; binds to Mig1p-binding sites in SUC2 promoter
YDR399W 0.59
HPT1
Dimeric hypoxanthine-guanine phosphoribosyltransferase, catalyzes the formation of both inosine monophosphate and guanosine monophosphate; mutations in the human homolog HPRT1 can cause Lesch-Nyhan syndrome and Kelley-Seegmiller syndrome
YMR205C 0.58
PFK2
Beta subunit of heterooctameric phosphofructokinase involved in glycolysis, indispensable for anaerobic growth, activated by fructose-2,6-bisphosphate and AMP, mutation inhibits glucose induction of cell cycle-related genes
YMR217W 0.58
GUA1
GMP synthase, an enzyme that catalyzes the second step in the biosynthesis of GMP from inosine 5'-phosphate (IMP); transcription is not subject to regulation by guanine but is negatively regulated by nutrient starvation
YLL034C 0.58
RIX7
Putative ATPase of the AAA family, required for export of pre-ribosomal large subunits from the nucleus; distributed between the nucleolus, nucleoplasm, and nuclear periphery depending on growth conditions
YPL265W 0.57
DIP5
Dicarboxylic amino acid permease, mediates high-affinity and high-capacity transport of L-glutamate and L-aspartate; also a transporter for Gln, Asn, Ser, Ala, and Gly
YGR229C 0.57
SMI1
Protein involved in the regulation of cell wall synthesis; proposed to be involved in coordinating cell cycle progression with cell wall integrity
YDR345C 0.57
HXT3
Low affinity glucose transporter of the major facilitator superfamily, expression is induced in low or high glucose conditions
YEL053W-A 0.57 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene YEL054C
YGR086C 0.57
PIL1
Primary component of eisosomes, which are large immobile cell cortex structures associated with endocytosis; null mutants show activation of Pkc1p/Ypk1p stress resistance pathways; detected in phosphorylated state in mitochondria
YNL141W 0.56
AAH1
Adenine deaminase (adenine aminohydrolase), converts adenine to hypoxanthine; involved in purine salvage; transcriptionally regulated by nutrient levels and growth phase; Aah1p degraded upon entry into quiescence via SCF and the proteasome
YDL075W 0.56
RPL31A
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl31Bp and has similarity to rat L31 ribosomal protein; associates with the karyopherin Sxm1p
YIR019C 0.56
MUC1
GPI-anchored cell surface glycoprotein (flocculin) required for pseudohyphal formation, invasive growth, flocculation, and biofilms; transcriptionally regulated by the MAPK pathway (via Ste12p and Tec1p) and the cAMP pathway (via Flo8p)
YMR113W 0.56
FOL3
Dihydrofolate synthetase, involved in folic acid biosynthesis; catalyzes the conversion of dihydropteroate to dihydrofolate in folate coenzyme biosynthesis
YLR353W 0.56
BUD8
Protein involved in bud-site selection; diploid mutants display a unipolar budding pattern instead of the wild-type bipolar pattern, and bud at the proximal pole
YGR108W 0.55
CLB1
B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the transition from G2 to M phase; accumulates during G2 and M, then targeted via a destruction box motif for ubiquitin-mediated degradation by the proteasome
YJL115W 0.55
ASF1
Nucleosome assembly factor, involved in chromatin assembly and disassembly, anti-silencing protein that causes derepression of silent loci when overexpressed; plays a role in regulating Ty1 transposition
YOR063W 0.55
RPL3
Protein component of the large (60S) ribosomal subunit, has similarity to E. coli L3 and rat L3 ribosomal proteins; involved in the replication and maintenance of killer double stranded RNA virus
YMR304C-A 0.55 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene SCW10
YCR098C 0.54
GIT1
Plasma membrane permease, mediates uptake of glycerophosphoinositol and glycerophosphocholine as sources of the nutrients inositol and phosphate; expression and transport rate are regulated by phosphate and inositol availability
YGR039W 0.54 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the Autonomously Replicating Sequence ARS722
YER019C-A 0.53
SBH2
Ssh1p-Sss1p-Sbh2p complex component, involved in protein translocation into the endoplasmic reticulum; homologous to Sbh1p
YPL243W 0.53
SRP68
Core component of the signal recognition particle (SRP) ribonucleoprotein (RNP) complex that functions in targeting nascent secretory proteins to the endoplasmic reticulum (ER) membrane
YPL143W 0.52
RPL33A
N-terminally acetylated ribosomal protein L37 of the large (60S) ribosomal subunit, nearly identical to Rpl33Bp and has similarity to rat L35a; rpl33a null mutant exhibits slow growth while rpl33a rpl33b double null mutant is inviable
YPL108W 0.52 Cytoplasmic protein of unknown function; non-essential gene that is induced in a GDH1 deleted strain with altered redox metabolism; GFP-fusion protein is induced in response to the DNA-damaging agent MMS
YEL056W 0.52
HAT2
Subunit of the Hat1p-Hat2p histone acetyltransferase complex; required for high affinity binding of the complex to free histone H4, thereby enhancing Hat1p activity; similar to human RbAp46 and 48; has a role in telomeric silencing
YOR107W 0.52
RGS2
Negative regulator of glucose-induced cAMP signaling; directly activates the GTPase activity of the heterotrimeric G protein alpha subunit Gpa2p
YEL014C 0.52 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YEL063C 0.51
CAN1
Plasma membrane arginine permease, requires phosphatidyl ethanolamine (PE) for localization, exclusively associated with lipid rafts; mutation confers canavanine resistance
YIL163C 0.51 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YER117W 0.51
RPL23B
Protein component of the large (60S) ribosomal subunit, identical to Rpl23Ap and has similarity to E. coli L14 and rat L23 ribosomal proteins
YNL289W 0.50
PCL1
Pho85 cyclin of the Pcl1,2-like subfamily, involved in entry into the mitotic cell cycle and regulation of morphogenesis, localizes to sites of polarized cell growth
YDR088C 0.50
SLU7
RNA splicing factor, required for ATP-independent portion of 2nd catalytic step of spliceosomal RNA splicing; interacts with Prp18p; contains zinc knuckle domain
YMR037C 0.50
MSN2
Transcriptional activator related to Msn4p; activated in stress conditions, which results in translocation from the cytoplasm to the nucleus; binds DNA at stress response elements of responsive genes, inducing gene expression
YBR007C 0.49
DSF2
Deletion suppressor of mpt5 mutation
YGR027C 0.49
RPS25A
Protein component of the small (40S) ribosomal subunit; nearly identical to Rps25Bp and has similarity to rat S25 ribosomal protein
YEL029C 0.49
BUD16
Putative pyridoxal kinase, key enzyme in vitamin B6 metabolism; involved in maintaining levels of pyridoxal 5'-phosphate, the active form of vitamin B6; required for genome integrity; homolog of E. coli PdxK; involved in bud-site selection
YPL050C 0.49
MNN9
Subunit of Golgi mannosyltransferase complex also containing Anp1p, Mnn10p, Mnn11p, and Hoc1p that mediates elongation of the polysaccharide mannan backbone; forms a separate complex with Van1p that is also involved in backbone elongation
YJL029C 0.49
VPS53
Component of the GARP (Golgi-associated retrograde protein) complex, Vps51p-Vps52p-Vps53p-Vps54p, which is required for the recycling of proteins from endosomes to the late Golgi; required for vacuolar protein sorting
YGR251W 0.49 Putative protein of unknown function; deletion mutant has defects in pre-rRNA processing; green fluorescent protein (GFP)-fusion protein localizes to both the nucleus and the nucleolus; YGR251W is an essential gene
YBR121C 0.49
GRS1
Cytoplasmic and mitochondrial glycyl-tRNA synthase that ligates glycine to the cognate anticodon bearing tRNA; transcription termination factor that may interact with the 3'-end of pre-mRNA to promote 3'-end formation
YOR130C 0.48
ORT1
Ornithine transporter of the mitochondrial inner membrane, exports ornithine from mitochondria as part of arginine biosynthesis; human ortholog is associated with hyperammonaemia-hyperornithinaemia-homocitrullinuria (HHH) syndrome
YPL053C 0.48
KTR6
Probable mannosylphosphate transferase involved in the synthesis of core oligosaccharides in protein glycosylation pathway; member of the KRE2/MNT1 mannosyltransferase family
YJL190C 0.48
RPS22A
Protein component of the small (40S) ribosomal subunit; nearly identical to Rps22Bp and has similarity to E. coli S8 and rat S15a ribosomal proteins
YOR052C 0.47 Nuclear protein of unknown function; expression induced by nitrogen limitation in a GLN3, GAT1-independent manner and by weak acid
YGR249W 0.47
MGA1
Protein similar to heat shock transcription factor; multicopy suppressor of pseudohyphal growth defects of ammonium permease mutants
YGL077C 0.47
HNM1
Choline/ethanolamine transporter; involved in the uptake of nitrogen mustard and the uptake of glycine betaine during hypersaline stress; co-regulated with phospholipid biosynthetic genes and negatively regulated by choline and myo-inositol
YKR099W 0.47
BAS1
Myb-related transcription factor involved in regulating basal and induced expression of genes of the purine and histidine biosynthesis pathways; also involved in regulation of meiotic recombination at specific genes
YGR266W 0.46 Protein of unknown function, predicted to contain a single transmembrane domain; localized to both the mitochondrial outer membrane and the plasma membrane
YLR312W-A 0.46
MRPL15
Mitochondrial ribosomal protein of the large subunit
YKL164C 0.46
PIR1
O-glycosylated protein required for cell wall stability; attached to the cell wall via beta-1,3-glucan; mediates mitochondrial translocation of Apn1p; expression regulated by the cell integrity pathway and by Swi5p during the cell cycle
YOR043W 0.46
WHI2
Protein required, with binding partner Psr1p, for full activation of the general stress response, possibly through Msn2p dephosphorylation; regulates growth during the diauxic shift; negative regulator of G1 cyclin expression
YDR385W 0.46
EFT2
Elongation factor 2 (EF-2), also encoded by EFT1; catalyzes ribosomal translocation during protein synthesis; contains diphthamide, the unique posttranslationally modified histidine residue specifically ADP-ribosylated by diphtheria toxin
YIL158W 0.45
AIM20
Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole; null mutant displays increased frequency of mitochondrial genome loss (petite formation)
YML021C 0.45
UNG1
Uracil-DNA glycosylase, required for repair of uracil in DNA formed by spontaneous cytosine deamination, not required for strand-specific mismatch repair, cell-cycle regulated, expressed in late G1, localizes to mitochondria and nucleus
YBL087C 0.45
RPL23A
Protein component of the large (60S) ribosomal subunit, identical to Rpl23Bp and has similarity to E. coli L14 and rat L23 ribosomal proteins
YGL039W 0.45 Oxidoreductase, catalyzes NADPH-dependent reduction of the bicyclic diketone bicyclo[2.2.2]octane-2,6-dione (BCO2,6D) to the chiral ketoalcohol (1R,4S,6S)-6-hydroxybicyclo[2.2.2]octane-2-one (BCO2one6ol)
YOR349W 0.45
CIN1
Tubulin folding factor D involved in beta-tubulin (Tub2p) folding; isolated as mutant with increased chromosome loss and sensitivity to benomyl
YDL236W 0.44
PHO13
Alkaline phosphatase specific for p-nitrophenyl phosphate, involved in dephosphorylation of histone II-A and casein
YCR101C 0.44 Putative protein of unknown function; localizes to the membrane fraction; YCR101C is not an essential gene
YMR290W-A 0.44 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data; overlaps 5' end of essential HAS1 gene which encodes an ATP-dependent RNA helicase
YMR015C 0.44
ERG5
C-22 sterol desaturase, a cytochrome P450 enzyme that catalyzes the formation of the C-22(23) double bond in the sterol side chain in ergosterol biosynthesis; may be a target of azole antifungal drugs
YER009W 0.43
NTF2
Nuclear envelope protein, interacts with GDP-bound Gsp1p and with proteins of the nuclear pore to transport Gsp1p into the nucleus where it is an essential player in nucleocytoplasmic transport
YMR016C 0.43
SOK2
Nuclear protein that plays a regulatory role in the cyclic AMP (cAMP)-dependent protein kinase (PKA) signal transduction pathway; negatively regulates pseudohyphal differentiation; homologous to several transcription factors
YMR112C 0.43
MED11
Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential protein
YOL139C 0.42
CDC33
Cytoplasmic mRNA cap binding protein; the eIF4E-cap complex is responsible for mediating cap-dependent mRNA translation via interactions with the translation initiation factor eIF4G (Tif4631p or Tif4632p)
YBR158W 0.42
AMN1
Protein required for daughter cell separation, multiple mitotic checkpoints, and chromosome stability; contains 12 degenerate leucine-rich repeat motifs; expression is induced by the Mitotic Exit Network (MEN)
YGR280C 0.42
PXR1
Essential protein involved in rRNA and snoRNA maturation; competes with TLC1 RNA for binding to Est2p, suggesting a role in negative regulation of telomerase; human homolog inhibits telomerase; contains a G-patch RNA interacting domain
YJL136C 0.42
RPS21B
Protein component of the small (40S) ribosomal subunit; nearly identical to Rps21Ap and has similarity to rat S21 ribosomal protein
YDR094W 0.42 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps verified ORF DNF2

Network of associatons between targets according to the STRING database.

First level regulatory network of DAL80

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.6 2.5 GO:0070417 response to cold(GO:0009409) cellular response to cold(GO:0070417)
0.6 5.5 GO:0070525 tRNA threonylcarbamoyladenosine metabolic process(GO:0070525)
0.6 2.4 GO:0090338 regulation of formin-nucleated actin cable assembly(GO:0090337) positive regulation of formin-nucleated actin cable assembly(GO:0090338)
0.6 1.7 GO:2000879 regulation of oligopeptide transport by regulation of transcription from RNA polymerase II promoter(GO:0035950) negative regulation of oligopeptide transport by negative regulation of transcription from RNA polymerase II promoter(GO:0035952) regulation of dipeptide transport by regulation of transcription from RNA polymerase II promoter(GO:0035953) negative regulation of dipeptide transport by negative regulation of transcription from RNA polymerase II promoter(GO:0035955) negative regulation of oligopeptide transport(GO:2000877) negative regulation of dipeptide transport(GO:2000879)
0.5 1.6 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.5 3.2 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.4 1.7 GO:0000461 endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000461)
0.4 2.5 GO:0009099 valine biosynthetic process(GO:0009099)
0.4 3.5 GO:0006814 sodium ion transport(GO:0006814)
0.4 0.7 GO:0071474 cellular hyperosmotic response(GO:0071474)
0.3 1.3 GO:1900434 filamentous growth of a population of unicellular organisms in response to starvation(GO:0036170) regulation of filamentous growth of a population of unicellular organisms in response to starvation(GO:1900434) positive regulation of filamentous growth of a population of unicellular organisms in response to starvation(GO:1900436)
0.3 1.0 GO:0032006 regulation of TOR signaling(GO:0032006)
0.3 1.0 GO:0006798 polyphosphate catabolic process(GO:0006798)
0.3 1.0 GO:0048024 regulation of RNA splicing(GO:0043484) regulation of mRNA splicing, via spliceosome(GO:0048024)
0.3 1.0 GO:0044209 AMP salvage(GO:0044209)
0.3 1.2 GO:0031565 obsolete cytokinesis checkpoint(GO:0031565)
0.3 2.1 GO:0010696 positive regulation of spindle pole body separation(GO:0010696)
0.3 2.4 GO:0000372 Group I intron splicing(GO:0000372) RNA splicing, via transesterification reactions with guanosine as nucleophile(GO:0000376)
0.3 0.6 GO:0032261 purine nucleotide salvage(GO:0032261)
0.3 1.7 GO:0006491 N-glycan processing(GO:0006491)
0.3 0.6 GO:0043096 purine nucleobase salvage(GO:0043096) adenine metabolic process(GO:0046083)
0.2 1.2 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.2 1.0 GO:0009423 chorismate biosynthetic process(GO:0009423)
0.2 1.0 GO:0035337 fatty-acyl-CoA metabolic process(GO:0035337)
0.2 1.2 GO:0007535 donor selection(GO:0007535)
0.2 0.7 GO:0034310 ethanol catabolic process(GO:0006068) acetate biosynthetic process(GO:0019413) primary alcohol catabolic process(GO:0034310)
0.2 1.1 GO:0070814 hydrogen sulfide metabolic process(GO:0070813) hydrogen sulfide biosynthetic process(GO:0070814)
0.2 0.6 GO:0045981 positive regulation of nucleotide metabolic process(GO:0045981) positive regulation of purine nucleotide metabolic process(GO:1900544)
0.2 0.6 GO:0043419 urea catabolic process(GO:0043419)
0.2 0.6 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.2 0.8 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.2 0.8 GO:0019287 isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287) isopentenyl diphosphate metabolic process(GO:0046490)
0.2 0.6 GO:0046901 tetrahydrofolylpolyglutamate metabolic process(GO:0046900) tetrahydrofolylpolyglutamate biosynthetic process(GO:0046901)
0.2 0.4 GO:0007188 G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger(GO:0007187) adenylate cyclase-modulating G-protein coupled receptor signaling pathway(GO:0007188)
0.2 1.7 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.2 6.0 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.2 0.9 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.2 0.7 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.2 1.1 GO:0042538 hyperosmotic salinity response(GO:0042538)
0.2 0.7 GO:0042357 thiamine diphosphate biosynthetic process(GO:0009229) thiamine diphosphate metabolic process(GO:0042357)
0.2 0.8 GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity(GO:0043433)
0.2 0.6 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
0.2 1.1 GO:0046501 protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501)
0.2 0.5 GO:0006529 asparagine biosynthetic process(GO:0006529)
0.2 0.5 GO:0045901 positive regulation of translational elongation(GO:0045901)
0.1 0.6 GO:0006177 GMP biosynthetic process(GO:0006177)
0.1 0.3 GO:1903313 positive regulation of mRNA metabolic process(GO:1903313)
0.1 0.4 GO:0009176 deoxyribonucleoside monophosphate biosynthetic process(GO:0009157) deoxyribonucleoside monophosphate metabolic process(GO:0009162) pyrimidine deoxyribonucleoside monophosphate metabolic process(GO:0009176) pyrimidine deoxyribonucleoside monophosphate biosynthetic process(GO:0009177)
0.1 0.7 GO:0016076 snRNA catabolic process(GO:0016076) snoRNA catabolic process(GO:0016077) nuclear polyadenylation-dependent snoRNA catabolic process(GO:0071036) nuclear polyadenylation-dependent snRNA catabolic process(GO:0071037)
0.1 1.6 GO:0033967 box C/D snoRNA metabolic process(GO:0033967) box C/D snoRNA processing(GO:0034963)
0.1 0.5 GO:0015809 arginine transport(GO:0015809)
0.1 0.3 GO:0042710 starch metabolic process(GO:0005982) starch catabolic process(GO:0005983) regulation of starch catabolic process by regulation of transcription from RNA polymerase II promoter(GO:0035956) positive regulation of starch catabolic process by positive regulation of transcription from RNA polymerase II promoter(GO:0035957) biofilm formation(GO:0042710) regulation of starch catabolic process(GO:2000881) positive regulation of starch catabolic process(GO:2000883) regulation of starch metabolic process(GO:2000904) positive regulation of starch metabolic process(GO:2000906)
0.1 0.8 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.1 3.6 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.1 0.4 GO:0097053 L-kynurenine metabolic process(GO:0097052) L-kynurenine catabolic process(GO:0097053)
0.1 1.0 GO:0015940 pantothenate metabolic process(GO:0015939) pantothenate biosynthetic process(GO:0015940)
0.1 16.7 GO:0002181 cytoplasmic translation(GO:0002181)
0.1 0.5 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.1 2.8 GO:0097384 ergosterol biosynthetic process(GO:0006696) phytosteroid biosynthetic process(GO:0016129) cellular alcohol biosynthetic process(GO:0044108) cellular lipid biosynthetic process(GO:0097384)
0.1 0.6 GO:0006279 premeiotic DNA replication(GO:0006279)
0.1 0.3 GO:0019673 GDP-mannose biosynthetic process(GO:0009298) GDP-mannose metabolic process(GO:0019673)
0.1 0.2 GO:0016926 protein desumoylation(GO:0016926)
0.1 1.7 GO:0051666 actin cortical patch localization(GO:0051666)
0.1 0.3 GO:0051029 rRNA export from nucleus(GO:0006407) rRNA transport(GO:0051029)
0.1 0.5 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 0.4 GO:0048313 Golgi inheritance(GO:0048313)
0.1 0.4 GO:0031118 rRNA pseudouridine synthesis(GO:0031118)
0.1 0.3 GO:0042992 intracellular lipid transport(GO:0032365) negative regulation of transcription factor import into nucleus(GO:0042992)
0.1 0.4 GO:0015883 FAD transport(GO:0015883)
0.1 0.4 GO:0006264 mitochondrial DNA replication(GO:0006264)
0.1 2.5 GO:0000967 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
0.1 4.6 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.1 0.3 GO:0008272 sulfate transport(GO:0008272)
0.1 0.6 GO:0070941 eisosome assembly(GO:0070941)
0.1 0.3 GO:0009186 deoxyribonucleoside diphosphate metabolic process(GO:0009186)
0.1 0.3 GO:1904667 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051436) regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051439) negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.1 0.4 GO:0072668 obsolete tubulin complex biogenesis(GO:0072668)
0.1 0.5 GO:0042219 cellular modified amino acid catabolic process(GO:0042219)
0.1 0.4 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.1 0.2 GO:0045048 protein insertion into ER membrane(GO:0045048)
0.1 0.3 GO:0031057 negative regulation of histone modification(GO:0031057)
0.1 0.6 GO:0006056 cell wall mannoprotein biosynthetic process(GO:0000032) mannoprotein metabolic process(GO:0006056) mannoprotein biosynthetic process(GO:0006057) cell wall glycoprotein biosynthetic process(GO:0031506)
0.1 4.4 GO:0007124 pseudohyphal growth(GO:0007124)
0.1 0.3 GO:0006048 UDP-N-acetylglucosamine metabolic process(GO:0006047) UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.1 0.3 GO:0042938 dipeptide transport(GO:0042938)
0.1 0.2 GO:0031114 negative regulation of microtubule depolymerization(GO:0007026) regulation of microtubule depolymerization(GO:0031114)
0.1 2.5 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.1 1.0 GO:0007120 axial cellular bud site selection(GO:0007120)
0.1 0.2 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143) tRNA thio-modification(GO:0034227)
0.1 0.2 GO:0001676 long-chain fatty acid metabolic process(GO:0001676)
0.1 0.2 GO:0046416 D-amino acid metabolic process(GO:0046416)
0.1 0.2 GO:0071031 nuclear mRNA surveillance of mRNA 3'-end processing(GO:0071031) nuclear retention of pre-mRNA with aberrant 3'-ends at the site of transcription(GO:0071049)
0.1 0.2 GO:0006741 NADP biosynthetic process(GO:0006741)
0.1 1.4 GO:0042790 transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:0042790)
0.1 0.3 GO:0006657 CDP-choline pathway(GO:0006657)
0.1 0.2 GO:0035307 positive regulation of phosphatase activity(GO:0010922) positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.1 0.2 GO:0031684 heterotrimeric G-protein complex cycle(GO:0031684)
0.1 0.2 GO:0000078 obsolete cytokinesis after mitosis checkpoint(GO:0000078)
0.1 0.4 GO:0009309 amine biosynthetic process(GO:0009309) cellular biogenic amine biosynthetic process(GO:0042401)
0.1 0.8 GO:0006037 cell wall chitin metabolic process(GO:0006037)
0.1 0.3 GO:0006857 oligopeptide transport(GO:0006857)
0.1 0.4 GO:0035304 regulation of phosphatase activity(GO:0010921) regulation of protein dephosphorylation(GO:0035304)
0.1 0.2 GO:0000092 mitotic anaphase B(GO:0000092) spindle assembly(GO:0051225)
0.1 0.3 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.1 1.2 GO:0009304 tRNA transcription(GO:0009304) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.1 0.7 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.1 0.3 GO:0034729 histone H3-K79 methylation(GO:0034729)
0.1 0.1 GO:0014070 response to organic cyclic compound(GO:0014070) response to cycloheximide(GO:0046898) response to ketone(GO:1901654)
0.1 0.3 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.1 0.3 GO:0044206 pyrimidine ribonucleotide salvage(GO:0010138) pyrimidine nucleotide salvage(GO:0032262) pyrimidine nucleoside salvage(GO:0043097) UMP salvage(GO:0044206)
0.1 1.1 GO:0042274 ribosomal small subunit biogenesis(GO:0042274)
0.1 0.1 GO:0072600 protein targeting to Golgi(GO:0000042) establishment of protein localization to Golgi(GO:0072600)
0.1 2.9 GO:0006606 protein import into nucleus(GO:0006606) nuclear import(GO:0051170) single-organism nuclear import(GO:1902593)
0.1 0.4 GO:0043457 regulation of cellular respiration(GO:0043457)
0.1 0.1 GO:0007121 bipolar cellular bud site selection(GO:0007121)
0.1 1.0 GO:0030488 tRNA methylation(GO:0030488)
0.1 4.1 GO:0006913 nucleocytoplasmic transport(GO:0006913)
0.1 0.1 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.1 0.2 GO:0015780 nucleotide-sugar transport(GO:0015780)
0.1 0.3 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.1 0.3 GO:0009306 protein secretion(GO:0009306)
0.1 0.4 GO:0046015 regulation of transcription by glucose(GO:0046015)
0.1 0.2 GO:0031167 rRNA methylation(GO:0031167)
0.1 0.3 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.1 0.6 GO:0015991 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.1 0.5 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.1 1.4 GO:0045047 protein targeting to ER(GO:0045047)
0.1 0.2 GO:0034389 lipid particle organization(GO:0034389)
0.1 0.1 GO:0018195 peptidyl-arginine modification(GO:0018195) peptidyl-arginine methylation(GO:0018216)
0.1 0.6 GO:0009303 rRNA transcription(GO:0009303)
0.1 0.1 GO:0034473 U1 snRNA 3'-end processing(GO:0034473)
0.1 0.4 GO:0051598 meiotic cell cycle checkpoint(GO:0033313) meiotic recombination checkpoint(GO:0051598)
0.1 0.8 GO:0043094 cellular metabolic compound salvage(GO:0043094)
0.0 0.1 GO:0015909 long-chain fatty acid transport(GO:0015909)
0.0 0.2 GO:0018904 glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.0 0.2 GO:0006026 aminoglycan catabolic process(GO:0006026) chitin catabolic process(GO:0006032) amino sugar catabolic process(GO:0046348) glucosamine-containing compound catabolic process(GO:1901072)
0.0 0.2 GO:0071406 response to methylmercury(GO:0051597) cellular response to methylmercury(GO:0071406)
0.0 0.1 GO:0033875 coenzyme A metabolic process(GO:0015936) coenzyme A biosynthetic process(GO:0015937) nucleoside bisphosphate metabolic process(GO:0033865) nucleoside bisphosphate biosynthetic process(GO:0033866) ribonucleoside bisphosphate metabolic process(GO:0033875) ribonucleoside bisphosphate biosynthetic process(GO:0034030) purine nucleoside bisphosphate metabolic process(GO:0034032) purine nucleoside bisphosphate biosynthetic process(GO:0034033)
0.0 2.6 GO:0006364 rRNA processing(GO:0006364)
0.0 0.3 GO:0045860 positive regulation of protein kinase activity(GO:0045860)
0.0 0.1 GO:0009847 spore germination(GO:0009847)
0.0 0.4 GO:0016233 telomere capping(GO:0016233)
0.0 0.1 GO:0031398 positive regulation of protein ubiquitination(GO:0031398) positive regulation of protein modification by small protein conjugation or removal(GO:1903322)
0.0 0.1 GO:0051446 positive regulation of meiotic nuclear division(GO:0045836) positive regulation of meiotic cell cycle(GO:0051446)
0.0 0.6 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 1.2 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 0.1 GO:0048211 Golgi vesicle docking(GO:0048211)
0.0 0.6 GO:0032986 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.0 0.0 GO:0042304 regulation of fatty acid biosynthetic process(GO:0042304)
0.0 0.2 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 1.0 GO:0030148 sphingolipid biosynthetic process(GO:0030148)
0.0 0.2 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560) protein to membrane docking(GO:0022615)
0.0 0.1 GO:0042256 mature ribosome assembly(GO:0042256)
0.0 1.0 GO:0006893 Golgi to plasma membrane transport(GO:0006893) vesicle-mediated transport to the plasma membrane(GO:0098876)
0.0 0.1 GO:0046777 protein autophosphorylation(GO:0046777)
0.0 0.1 GO:0001109 promoter clearance during DNA-templated transcription(GO:0001109) promoter clearance from RNA polymerase II promoter(GO:0001111)
0.0 0.1 GO:0000022 mitotic spindle elongation(GO:0000022) spindle elongation(GO:0051231)
0.0 0.3 GO:1903338 regulation of cell wall organization or biogenesis(GO:1903338)
0.0 0.4 GO:0006446 regulation of translational initiation(GO:0006446)
0.0 0.2 GO:0032988 ribonucleoprotein complex disassembly(GO:0032988)
0.0 0.2 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.0 0.1 GO:0000080 mitotic G1 phase(GO:0000080) G1 phase(GO:0051318)
0.0 0.4 GO:0006469 negative regulation of protein kinase activity(GO:0006469) negative regulation of kinase activity(GO:0033673)
0.0 1.3 GO:0007264 small GTPase mediated signal transduction(GO:0007264)
0.0 0.2 GO:0030846 termination of RNA polymerase II transcription, poly(A)-coupled(GO:0030846)
0.0 0.1 GO:0000709 meiotic joint molecule formation(GO:0000709)
0.0 0.2 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.4 GO:0006284 base-excision repair(GO:0006284)
0.0 0.1 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.1 GO:0044070 regulation of anion transport(GO:0044070)
0.0 0.8 GO:0006413 translational initiation(GO:0006413)
0.0 0.1 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0015848 spermidine transport(GO:0015848)
0.0 0.0 GO:0040008 regulation of growth(GO:0040008)
0.0 0.1 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.0 GO:2000058 regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000058)
0.0 0.1 GO:0030031 cell projection organization(GO:0030030) cell projection assembly(GO:0030031)
0.0 1.9 GO:0030036 actin cytoskeleton organization(GO:0030036)
0.0 0.1 GO:0031929 TOR signaling(GO:0031929)
0.0 0.2 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.0 0.8 GO:0006896 Golgi to vacuole transport(GO:0006896)
0.0 0.1 GO:0009231 riboflavin metabolic process(GO:0006771) riboflavin biosynthetic process(GO:0009231)
0.0 0.3 GO:0006885 regulation of pH(GO:0006885)
0.0 0.4 GO:0046903 secretion by cell(GO:0032940) secretion(GO:0046903)
0.0 0.0 GO:0051196 regulation of cofactor metabolic process(GO:0051193) regulation of coenzyme metabolic process(GO:0051196) regulation of purine nucleotide metabolic process(GO:1900542)
0.0 0.1 GO:0000011 vacuole inheritance(GO:0000011)
0.0 0.0 GO:0060258 negative regulation of growth(GO:0045926) negative regulation of filamentous growth(GO:0060258)
0.0 0.1 GO:0007232 osmosensory signaling pathway via Sho1 osmosensor(GO:0007232)
0.0 0.1 GO:0019401 glycerol biosynthetic process(GO:0006114) alditol biosynthetic process(GO:0019401)
0.0 0.2 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.3 GO:0006379 mRNA cleavage(GO:0006379)
0.0 0.1 GO:0035303 regulation of dephosphorylation(GO:0035303)
0.0 0.0 GO:0010942 positive regulation of cell death(GO:0010942) positive regulation of apoptotic process(GO:0043065) positive regulation of programmed cell death(GO:0043068)
0.0 0.2 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.1 GO:0007109 obsolete cytokinesis, completion of separation(GO:0007109)
0.0 0.2 GO:0006189 IMP biosynthetic process(GO:0006188) 'de novo' IMP biosynthetic process(GO:0006189) IMP metabolic process(GO:0046040)
0.0 0.1 GO:0048478 replication fork protection(GO:0048478)
0.0 0.2 GO:0006591 ornithine metabolic process(GO:0006591)
0.0 0.1 GO:0031134 sister chromatid biorientation(GO:0031134)
0.0 0.2 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.1 GO:0016559 peroxisome fission(GO:0016559)
0.0 0.1 GO:0046655 folic acid metabolic process(GO:0046655) folic acid biosynthetic process(GO:0046656)
0.0 0.1 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.0 0.2 GO:0052803 histidine biosynthetic process(GO:0000105) histidine metabolic process(GO:0006547) imidazole-containing compound metabolic process(GO:0052803)
0.0 0.1 GO:0000388 spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)(GO:0000388)
0.0 0.1 GO:0048017 inositol lipid-mediated signaling(GO:0048017)
0.0 0.3 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.0 GO:0030656 regulation of vitamin metabolic process(GO:0030656) positive regulation of vitamin metabolic process(GO:0046136) regulation of thiamine biosynthetic process(GO:0070623) positive regulation of thiamine biosynthetic process(GO:0090180)
0.0 0.4 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.1 GO:0016479 negative regulation of transcription from RNA polymerase I promoter(GO:0016479)
0.0 0.1 GO:1900101 regulation of endoplasmic reticulum unfolded protein response(GO:1900101)
0.0 0.1 GO:0032508 DNA duplex unwinding(GO:0032508)
0.0 0.1 GO:0006561 proline biosynthetic process(GO:0006561)
0.0 0.2 GO:0006734 NADH metabolic process(GO:0006734)
0.0 0.0 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.1 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.0 0.2 GO:0051493 regulation of cytoskeleton organization(GO:0051493)
0.0 0.1 GO:0072337 modified amino acid transport(GO:0072337)
0.0 0.0 GO:0071034 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0 0.3 GO:0045324 late endosome to vacuole transport(GO:0045324)
0.0 0.5 GO:0008033 tRNA processing(GO:0008033)
0.0 0.1 GO:0000086 G2/M transition of mitotic cell cycle(GO:0000086) cell cycle G2/M phase transition(GO:0044839)
0.0 0.0 GO:0042559 folic acid-containing compound biosynthetic process(GO:0009396) pteridine-containing compound biosynthetic process(GO:0042559)
0.0 0.1 GO:0000321 re-entry into mitotic cell cycle(GO:0000320) re-entry into mitotic cell cycle after pheromone arrest(GO:0000321)
0.0 0.4 GO:0016311 dephosphorylation(GO:0016311)
0.0 0.0 GO:0032042 mitochondrial DNA metabolic process(GO:0032042)
0.0 0.0 GO:0051469 vesicle fusion with vacuole(GO:0051469)
0.0 0.0 GO:0031338 regulation of vesicle fusion(GO:0031338) SNARE complex assembly(GO:0035493)
0.0 0.1 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 0.1 GO:0006415 translational termination(GO:0006415)
0.0 0.2 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.0 0.2 GO:0040023 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023) nucleus localization(GO:0051647)
0.0 0.2 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.2 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.0 0.1 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0 0.2 GO:0006633 fatty acid biosynthetic process(GO:0006633)
0.0 0.1 GO:1901661 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) ketone biosynthetic process(GO:0042181) quinone metabolic process(GO:1901661) quinone biosynthetic process(GO:1901663)
0.0 0.1 GO:0034982 mitochondrial protein processing(GO:0034982)
0.0 0.0 GO:0043270 positive regulation of ion transport(GO:0043270)
0.0 0.0 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 5.2 GO:0000408 EKC/KEOPS complex(GO:0000408)
1.0 3.0 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.7 3.3 GO:0005771 multivesicular body(GO:0005771)
0.5 1.6 GO:0005662 DNA replication factor A complex(GO:0005662)
0.5 1.4 GO:0070545 PeBoW complex(GO:0070545)
0.5 1.4 GO:0017102 methionyl glutamyl tRNA synthetase complex(GO:0017102)
0.4 1.2 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.2 1.0 GO:0097042 extrinsic component of fungal-type vacuolar membrane(GO:0097042)
0.2 0.8 GO:0017053 transcriptional repressor complex(GO:0017053)
0.2 0.6 GO:0071261 Ssh1 translocon complex(GO:0071261)
0.2 0.7 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.2 0.9 GO:0030689 Noc complex(GO:0030689)
0.2 14.1 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.2 0.6 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.2 0.8 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.2 0.9 GO:0035339 serine C-palmitoyltransferase complex(GO:0017059) SPOTS complex(GO:0035339)
0.1 9.1 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 0.7 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 2.0 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 0.8 GO:0000136 alpha-1,6-mannosyltransferase complex(GO:0000136)
0.1 0.1 GO:0030658 transport vesicle membrane(GO:0030658)
0.1 0.8 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.1 0.5 GO:0000938 GARP complex(GO:0000938)
0.1 0.4 GO:0030869 RENT complex(GO:0030869)
0.1 1.8 GO:0005940 septin ring(GO:0005940)
0.1 0.4 GO:0033186 CAF-1 complex(GO:0033186)
0.1 0.7 GO:0031499 TRAMP complex(GO:0031499)
0.1 1.0 GO:0030681 nucleolar ribonuclease P complex(GO:0005655) multimeric ribonuclease P complex(GO:0030681)
0.1 0.6 GO:0034456 UTP-C complex(GO:0034456)
0.1 0.8 GO:0005724 nuclear heterochromatin(GO:0005720) nuclear telomeric heterochromatin(GO:0005724) telomeric heterochromatin(GO:0031933)
0.1 0.6 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.1 3.8 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.1 0.7 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1 0.6 GO:0032126 eisosome(GO:0032126)
0.1 4.5 GO:0030684 preribosome(GO:0030684)
0.1 0.1 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.1 0.4 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 0.4 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.1 0.3 GO:0042788 polysomal ribosome(GO:0042788)
0.1 0.7 GO:0042597 periplasmic space(GO:0042597)
0.1 9.0 GO:0005730 nucleolus(GO:0005730)
0.1 0.5 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221) proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 0.1 GO:0005688 U6 snRNP(GO:0005688)
0.1 2.2 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 0.3 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.1 0.2 GO:0070985 TFIIK complex(GO:0070985)
0.1 0.2 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.1 0.5 GO:0051233 spindle midzone(GO:0051233)
0.1 0.4 GO:0016459 myosin complex(GO:0016459)
0.1 0.7 GO:0000243 commitment complex(GO:0000243)
0.1 0.2 GO:0070939 Dsl1p complex(GO:0070939)
0.1 0.2 GO:0043529 GET complex(GO:0043529)
0.1 0.2 GO:0016587 Isw1 complex(GO:0016587)
0.1 0.4 GO:0000782 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.1 0.7 GO:0000786 nucleosome(GO:0000786)
0.1 0.4 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
0.1 0.3 GO:0000133 polarisome(GO:0000133)
0.0 0.3 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.0 0.2 GO:0033179 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220) proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.1 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.3 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.2 GO:0030907 MBF transcription complex(GO:0030907)
0.0 0.2 GO:0044462 cell wall part(GO:0044426) external encapsulating structure part(GO:0044462)
0.0 0.8 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.2 GO:0034044 exomer complex(GO:0034044)
0.0 0.1 GO:0046930 pore complex(GO:0046930)
0.0 0.2 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 1.4 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 0.1 GO:0000131 incipient cellular bud site(GO:0000131)
0.0 0.2 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 0.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 6.4 GO:0005933 cellular bud(GO:0005933)
0.0 0.0 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.0 0.6 GO:0016586 RSC complex(GO:0016586)
0.0 1.2 GO:0005811 lipid particle(GO:0005811)
0.0 0.1 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.1 GO:0070762 nuclear pore transmembrane ring(GO:0070762)
0.0 0.2 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.1 GO:0034990 mitotic cohesin complex(GO:0030892) nuclear mitotic cohesin complex(GO:0034990)
0.0 0.3 GO:0042575 DNA polymerase complex(GO:0042575)
0.0 0.2 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.0 0.4 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 2.4 GO:0000139 Golgi membrane(GO:0000139)
0.0 0.2 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 1.1 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.3 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.2 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.1 GO:0000111 nucleotide-excision repair factor 2 complex(GO:0000111)
0.0 0.4 GO:0022626 cytosolic ribosome(GO:0022626)
0.0 0.1 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.1 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.2 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.2 GO:0034399 nuclear periphery(GO:0034399)
0.0 0.1 GO:0070772 PAS complex(GO:0070772)
0.0 0.2 GO:0030118 clathrin coat(GO:0030118)
0.0 0.2 GO:0000812 Swr1 complex(GO:0000812)
0.0 0.2 GO:0071782 cortical endoplasmic reticulum(GO:0032541) endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.0 0.1 GO:0000113 nucleotide-excision repair factor 4 complex(GO:0000113)
0.0 0.1 GO:0042555 MCM complex(GO:0042555)
0.0 0.1 GO:0000229 cytoplasmic chromosome(GO:0000229) mitochondrial chromosome(GO:0000262)
0.0 0.1 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.3 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.1 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.3 GO:0070847 core mediator complex(GO:0070847)
0.0 0.0 GO:0097344 Rix1 complex(GO:0097344)
0.0 0.0 GO:0044611 nuclear pore inner ring(GO:0044611)
0.0 0.1 GO:0042729 DASH complex(GO:0042729)
0.0 0.1 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.0 0.1 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.1 GO:0005798 Golgi-associated vesicle(GO:0005798)
0.0 0.1 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 1.1 GO:0005840 ribosome(GO:0005840)
0.0 0.1 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.2 GO:0031298 replication fork protection complex(GO:0031298)
0.0 0.0 GO:0071561 nucleus-vacuole junction(GO:0071561)
0.0 0.0 GO:0035649 Nrd1 complex(GO:0035649)
0.0 0.0 GO:0000417 HIR complex(GO:0000417)
0.0 0.0 GO:0034518 RNA cap binding complex(GO:0034518)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.8 3.0 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.5 5.4 GO:0031490 chromatin DNA binding(GO:0031490)
0.5 2.4 GO:0008536 Ran GTPase binding(GO:0008536)
0.4 2.1 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.3 1.0 GO:0072341 modified amino acid binding(GO:0072341)
0.3 2.1 GO:0016408 C-acyltransferase activity(GO:0016408)
0.3 0.9 GO:0015114 phosphate ion transmembrane transporter activity(GO:0015114)
0.3 0.9 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.3 1.5 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.3 1.2 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.2 1.1 GO:0004075 biotin carboxylase activity(GO:0004075)
0.2 0.9 GO:0019206 nucleoside kinase activity(GO:0019206)
0.2 2.4 GO:0015079 potassium ion transmembrane transporter activity(GO:0015079)
0.2 1.0 GO:0004707 MAP kinase activity(GO:0004707)
0.2 1.0 GO:0036002 pre-mRNA binding(GO:0036002)
0.2 0.8 GO:0016854 racemase and epimerase activity(GO:0016854)
0.2 0.8 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.2 0.6 GO:0004326 tetrahydrofolylpolyglutamate synthase activity(GO:0004326)
0.2 0.7 GO:0004338 glucan exo-1,3-beta-glucosidase activity(GO:0004338)
0.2 0.7 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.2 0.7 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.2 0.7 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.2 0.5 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.2 0.5 GO:0051010 microtubule plus-end binding(GO:0051010)
0.2 1.0 GO:0016744 transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.2 1.0 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.2 2.7 GO:0070491 repressing transcription factor binding(GO:0070491)
0.2 0.8 GO:0070300 phosphatidic acid binding(GO:0070300)
0.2 0.5 GO:0015166 polyol transmembrane transporter activity(GO:0015166)
0.1 0.6 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 0.4 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.1 2.0 GO:0001054 RNA polymerase I activity(GO:0001054)
0.1 0.8 GO:0015198 oligopeptide transporter activity(GO:0015198)
0.1 0.6 GO:0004497 monooxygenase activity(GO:0004497)
0.1 1.0 GO:0030145 manganese ion binding(GO:0030145)
0.1 0.9 GO:0016778 diphosphotransferase activity(GO:0016778)
0.1 0.4 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.1 0.5 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 0.4 GO:0016433 rRNA (adenine) methyltransferase activity(GO:0016433)
0.1 0.5 GO:0004771 sterol esterase activity(GO:0004771)
0.1 0.5 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.1 0.1 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 5.3 GO:0019843 rRNA binding(GO:0019843)
0.1 0.7 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.1 1.2 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 20.0 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 0.6 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.1 3.4 GO:0016876 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.1 2.3 GO:0019901 protein kinase binding(GO:0019901)
0.1 0.4 GO:0015230 FAD transmembrane transporter activity(GO:0015230)
0.1 0.4 GO:0015665 alcohol transmembrane transporter activity(GO:0015665)
0.1 0.3 GO:0015116 secondary active sulfate transmembrane transporter activity(GO:0008271) sulfate transmembrane transporter activity(GO:0015116)
0.1 1.0 GO:0000171 ribonuclease MRP activity(GO:0000171)
0.1 0.8 GO:0000009 alpha-1,6-mannosyltransferase activity(GO:0000009)
0.1 0.5 GO:0008443 phosphofructokinase activity(GO:0008443)
0.1 0.3 GO:0070568 guanylyltransferase activity(GO:0070568)
0.1 0.3 GO:0051219 phosphoprotein binding(GO:0051219)
0.1 0.5 GO:0003725 double-stranded RNA binding(GO:0003725)
0.1 0.3 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.1 0.4 GO:0000146 microfilament motor activity(GO:0000146)
0.1 0.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 0.1 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.1 0.2 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.1 0.2 GO:0000339 RNA cap binding(GO:0000339)
0.1 0.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 0.4 GO:0019104 DNA N-glycosylase activity(GO:0019104)
0.1 0.9 GO:0005199 structural constituent of cell wall(GO:0005199)
0.1 0.2 GO:0003951 NAD+ kinase activity(GO:0003951) NADH kinase activity(GO:0042736)
0.1 0.1 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 0.3 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 2.6 GO:0030674 protein binding, bridging(GO:0030674)
0.1 0.7 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 0.5 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 0.3 GO:0008525 phosphatidylcholine transporter activity(GO:0008525) phosphatidylinositol transporter activity(GO:0008526)
0.1 0.3 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.1 0.2 GO:0004622 lysophospholipase activity(GO:0004622)
0.1 0.4 GO:0019211 phosphatase activator activity(GO:0019211)
0.1 1.8 GO:0003743 translation initiation factor activity(GO:0003743)
0.1 0.5 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.1 0.5 GO:0019904 protein domain specific binding(GO:0019904)
0.1 0.2 GO:0008312 7S RNA binding(GO:0008312)
0.1 1.6 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.1 0.8 GO:0030515 snoRNA binding(GO:0030515)
0.1 0.2 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438) phosphatidylinositol monophosphate phosphatase activity(GO:0052744)
0.1 0.6 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.1 3.7 GO:0003924 GTPase activity(GO:0003924)
0.1 0.1 GO:0004529 exodeoxyribonuclease activity(GO:0004529)
0.1 0.3 GO:0070546 L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.1 0.1 GO:0019003 GDP binding(GO:0019003)
0.1 0.2 GO:0001128 RNA polymerase II transcription coactivator activity involved in preinitiation complex assembly(GO:0001128)
0.1 0.7 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.1 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.2 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.9 GO:0050661 NADP binding(GO:0050661)
0.0 0.2 GO:0008297 single-stranded DNA exodeoxyribonuclease activity(GO:0008297) single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.0 0.5 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.0 0.3 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.3 GO:0001004 RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003) transcription factor activity, RNA polymerase III promoter sequence-specific binding, TFIIIB recruiting(GO:0001004) transcription factor activity, RNA polymerase III type 1 promoter sequence-specific binding, TFIIIB recruiting(GO:0001005) transcription factor activity, RNA polymerase III type 2 promoter sequence-specific binding, TFIIIB recruiting(GO:0001008) RNA polymerase III type 2 promoter DNA binding(GO:0001031) RNA polymerase III transcription factor activity, sequence-specific DNA binding(GO:0001034)
0.0 0.2 GO:0005338 nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.0 0.1 GO:0008144 drug binding(GO:0008144)
0.0 0.1 GO:0004619 phosphoglycerate mutase activity(GO:0004619)
0.0 0.1 GO:0015088 copper uptake transmembrane transporter activity(GO:0015088)
0.0 0.7 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.1 GO:0005253 anion channel activity(GO:0005253) voltage-gated anion channel activity(GO:0008308) porin activity(GO:0015288) wide pore channel activity(GO:0022829)
0.0 0.2 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.3 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0 2.3 GO:0030695 GTPase regulator activity(GO:0030695)
0.0 0.6 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.1 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037) glutathione disulfide oxidoreductase activity(GO:0015038)
0.0 0.2 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.2 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.2 GO:0043139 5'-3' DNA helicase activity(GO:0043139) ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 1.4 GO:0042393 histone binding(GO:0042393)
0.0 0.5 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.3 GO:0008173 RNA methyltransferase activity(GO:0008173)
0.0 0.6 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.0 0.1 GO:0016273 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.0 0.2 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.0 0.1 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.0 0.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.2 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.1 GO:0000150 recombinase activity(GO:0000150)
0.0 0.9 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 0.1 GO:0001097 TFIIH-class transcription factor binding(GO:0001097)
0.0 0.1 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0 5.9 GO:0003723 RNA binding(GO:0003723)
0.0 0.3 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 0.3 GO:0008408 3'-5' exonuclease activity(GO:0008408)
0.0 0.3 GO:0030276 clathrin binding(GO:0030276)
0.0 0.1 GO:0004100 chitin synthase activity(GO:0004100)
0.0 0.1 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.3 GO:0015605 organophosphate ester transmembrane transporter activity(GO:0015605)
0.0 0.2 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.1 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 0.1 GO:0000182 rDNA binding(GO:0000182)
0.0 0.2 GO:0004713 protein tyrosine kinase activity(GO:0004713)
0.0 0.1 GO:0016840 carbon-nitrogen lyase activity(GO:0016840)
0.0 0.1 GO:0008902 hydroxymethylpyrimidine kinase activity(GO:0008902) phosphomethylpyrimidine kinase activity(GO:0008972)
0.0 0.1 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.1 GO:0004930 G-protein coupled receptor activity(GO:0004930)
0.0 0.1 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0 0.3 GO:0019001 GTP binding(GO:0005525) guanyl nucleotide binding(GO:0019001) guanyl ribonucleotide binding(GO:0032561)
0.0 0.1 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0 0.4 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 0.1 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.1 GO:0004620 phospholipase activity(GO:0004620)
0.0 0.5 GO:0015631 tubulin binding(GO:0015631)
0.0 0.1 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.0 0.2 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.0 0.7 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.0 0.1 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.2 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.4 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.5 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 0.2 GO:0015616 DNA translocase activity(GO:0015616)
0.0 0.0 GO:1901618 organic hydroxy compound transmembrane transporter activity(GO:1901618)
0.0 0.1 GO:0000297 spermine transmembrane transporter activity(GO:0000297)
0.0 0.0 GO:0031369 translation initiation factor binding(GO:0031369)
0.0 0.3 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.1 GO:0016725 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups(GO:0016725) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.3 GO:0019213 deacetylase activity(GO:0019213)
0.0 0.0 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.1 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.0 GO:0032137 guanine/thymine mispair binding(GO:0032137)
0.0 0.1 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.1 GO:0051920 thioredoxin peroxidase activity(GO:0008379) peroxiredoxin activity(GO:0051920)
0.0 0.0 GO:0019202 amino acid kinase activity(GO:0019202)
0.0 0.0 GO:0003680 AT DNA binding(GO:0003680)
0.0 1.1 GO:0003690 double-stranded DNA binding(GO:0003690)
0.0 0.6 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.1 GO:0008170 N-methyltransferase activity(GO:0008170)
0.0 0.0 GO:0015298 monovalent cation:proton antiporter activity(GO:0005451) solute:cation antiporter activity(GO:0015298) solute:proton antiporter activity(GO:0015299) sodium:proton antiporter activity(GO:0015385) cation:cation antiporter activity(GO:0015491)
0.0 0.1 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 0.0 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 PID SHP2 PATHWAY SHP2 signaling
0.2 0.6 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.2 0.6 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.1 0.4 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.1 0.3 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 0.7 NABA MATRISOME ASSOCIATED Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors
0.1 0.3 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 0.1 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.0 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.1 PID P73PATHWAY p73 transcription factor network
0.0 0.1 PID E2F PATHWAY E2F transcription factor network
0.0 0.0 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.0 0.0 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.1 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 REACTOME SIGNALING BY INSULIN RECEPTOR Genes involved in Signaling by Insulin receptor
0.4 0.4 REACTOME SIGNALING BY FGFR IN DISEASE Genes involved in Signaling by FGFR in disease
0.3 1.9 REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
0.2 0.4 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.2 0.2 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.2 2.6 REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION Genes involved in 3' -UTR-mediated translational regulation
0.1 0.4 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 0.8 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.1 0.9 REACTOME SIGNALING BY GPCR Genes involved in Signaling by GPCR
0.1 0.5 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.2 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 0.1 REACTOME PLATELET ACTIVATION SIGNALING AND AGGREGATION Genes involved in Platelet activation, signaling and aggregation
0.0 0.1 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.1 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.3 REACTOME M G1 TRANSITION Genes involved in M/G1 Transition
0.0 0.1 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.0 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.0 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing