Results for DAL80
Z-value: 0.54
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Transcription factors associated with DAL80
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
DAL80
|
S000001742 | Negative regulator of genes in multiple nitrogen degradation pathways |
Activity-expression correlation:
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| YKR038C Show fit | 5.18 |
Putative glycoprotease proposed to be in transcription as a component of the EKC protein complex with Bud32p, Cgi121p, Pcc1p, and Gon7p; also identified as a component of the KEOPS protein complex |
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| YDL211C Show fit | 4.92 |
Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole |
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| YKR092C Show fit | 4.60 |
Nucleolar, serine-rich protein with a role in preribosome assembly or transport; may function as a chaperone of small nucleolar ribonucleoprotein particles (snoRNPs); immunologically and structurally to rat Nopp140 |
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| YKR039W Show fit | 4.39 |
General amino acid permease; localization to the plasma membrane is regulated by nitrogen source |
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| YOR315W Show fit | 3.20 |
Nuclear protein, putative transcription factor required for growth of superficial pseudohyphae (which do not invade the agar substrate) but not for invasive pseudohyphal growth; may act together with Phd1p; potential Cdc28p substrate |
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| YJR094W-A Show fit | 3.01 |
Protein component of the large (60S) ribosomal subunit, identical to Rpl43Ap and has similarity to rat L37a ribosomal protein |
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| YDR041W Show fit | 2.95 |
Mitochondrial ribosomal protein of the small subunit, has similarity to E. coli S10 ribosomal protein; essential for viability, unlike most other mitoribosomal proteins |
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| YOL127W Show fit | 2.90 |
Primary rRNA-binding ribosomal protein component of the large (60S) ribosomal subunit, has similarity to E. coli L23 and rat L23a ribosomal proteins; binds to 26S rRNA via a conserved C-terminal motif |
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| YDR040C Show fit | 2.58 |
P-type ATPase sodium pump, involved in Na+ and Li+ efflux to allow salt tolerance |
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| YPR169W-A Show fit | 2.51 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps two other dubious ORFs: YPR170C and YPR170W-B |
Network of associatons between targets according to the STRING database.
First level regulatory network of DAL80
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 16.7 | GO:0002181 | cytoplasmic translation(GO:0002181) |
| 0.2 | 6.0 | GO:0000027 | ribosomal large subunit assembly(GO:0000027) |
| 0.6 | 5.5 | GO:0070525 | tRNA threonylcarbamoyladenosine metabolic process(GO:0070525) |
| 0.1 | 4.6 | GO:0042273 | ribosomal large subunit biogenesis(GO:0042273) |
| 0.1 | 4.4 | GO:0007124 | pseudohyphal growth(GO:0007124) |
| 0.1 | 4.1 | GO:0006913 | nucleocytoplasmic transport(GO:0006913) |
| 0.1 | 3.6 | GO:0006418 | tRNA aminoacylation for protein translation(GO:0006418) |
| 0.4 | 3.5 | GO:0006814 | sodium ion transport(GO:0006814) |
| 0.5 | 3.2 | GO:0043137 | DNA replication, removal of RNA primer(GO:0043137) |
| 0.1 | 2.9 | GO:0006606 | protein import into nucleus(GO:0006606) nuclear import(GO:0051170) single-organism nuclear import(GO:1902593) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 14.1 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.1 | 9.1 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 0.1 | 9.0 | GO:0005730 | nucleolus(GO:0005730) |
| 0.0 | 6.4 | GO:0005933 | cellular bud(GO:0005933) |
| 1.0 | 5.2 | GO:0000408 | EKC/KEOPS complex(GO:0000408) |
| 0.1 | 4.5 | GO:0030684 | preribosome(GO:0030684) |
| 0.1 | 3.8 | GO:0030687 | preribosome, large subunit precursor(GO:0030687) |
| 0.7 | 3.3 | GO:0005771 | multivesicular body(GO:0005771) |
| 1.0 | 3.0 | GO:0032299 | ribonuclease H2 complex(GO:0032299) |
| 0.0 | 2.4 | GO:0000139 | Golgi membrane(GO:0000139) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 20.0 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 0.0 | 5.9 | GO:0003723 | RNA binding(GO:0003723) |
| 0.5 | 5.4 | GO:0031490 | chromatin DNA binding(GO:0031490) |
| 0.1 | 5.3 | GO:0019843 | rRNA binding(GO:0019843) |
| 0.1 | 3.7 | GO:0003924 | GTPase activity(GO:0003924) |
| 0.1 | 3.4 | GO:0016876 | aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876) |
| 0.8 | 3.0 | GO:0004523 | RNA-DNA hybrid ribonuclease activity(GO:0004523) |
| 0.2 | 2.7 | GO:0070491 | repressing transcription factor binding(GO:0070491) |
| 0.1 | 2.6 | GO:0030674 | protein binding, bridging(GO:0030674) |
| 0.8 | 2.4 | GO:0004826 | phenylalanine-tRNA ligase activity(GO:0004826) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.8 | 2.4 | PID SHP2 PATHWAY | SHP2 signaling |
| 0.1 | 0.7 | NABA MATRISOME ASSOCIATED | Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors |
| 0.2 | 0.6 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.2 | 0.6 | PID INTEGRIN A4B1 PATHWAY | Alpha4 beta1 integrin signaling events |
| 0.1 | 0.4 | PID ERBB2 ERBB3 PATHWAY | ErbB2/ErbB3 signaling events |
| 0.1 | 0.3 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 0.1 | 0.3 | PID UPA UPAR PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
| 0.1 | 0.1 | PID RB 1PATHWAY | Regulation of retinoblastoma protein |
| 0.0 | 0.1 | PID P73PATHWAY | p73 transcription factor network |
| 0.0 | 0.1 | PID E2F PATHWAY | E2F transcription factor network |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 2.6 | REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION | Genes involved in 3' -UTR-mediated translational regulation |
| 0.8 | 2.4 | REACTOME SIGNALING BY INSULIN RECEPTOR | Genes involved in Signaling by Insulin receptor |
| 0.3 | 1.9 | REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S | Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S |
| 0.1 | 0.9 | REACTOME SIGNALING BY GPCR | Genes involved in Signaling by GPCR |
| 0.1 | 0.8 | REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE | Genes involved in SRP-dependent cotranslational protein targeting to membrane |
| 0.1 | 0.5 | REACTOME PPARA ACTIVATES GENE EXPRESSION | Genes involved in PPARA Activates Gene Expression |
| 0.4 | 0.4 | REACTOME SIGNALING BY FGFR IN DISEASE | Genes involved in Signaling by FGFR in disease |
| 0.2 | 0.4 | REACTOME SHC1 EVENTS IN ERBB4 SIGNALING | Genes involved in SHC1 events in ERBB4 signaling |
| 0.1 | 0.4 | REACTOME CITRIC ACID CYCLE TCA CYCLE | Genes involved in Citric acid cycle (TCA cycle) |
| 0.0 | 0.3 | REACTOME M G1 TRANSITION | Genes involved in M/G1 Transition |