Results for CEP3
Z-value: 0.74
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Transcription factors associated with CEP3
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
CEP3
|
S000004778 | Essential kinetochore protein |
Activity-expression correlation:
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| YHR092C Show fit | 2.39 |
High-affinity glucose transporter of the major facilitator superfamily, expression is induced by low levels of glucose and repressed by high levels of glucose |
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| YBR054W Show fit | 1.39 |
Putative protein of unknown function; the authentic, non-tagged protein is detected in a phosphorylated state in highly purified mitochondria in high-throughput studies; transcriptionally regulated by Haa1p |
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| YLL053C Show fit | 1.25 |
Putative protein; in the Sigma 1278B strain background YLL053C is contiguous with AQY2 which encodes an aquaporin |
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| YDR278C Show fit | 1.21 |
Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data |
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| YAR060C Show fit | 1.13 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data |
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| YJL216C Show fit | 1.12 |
Protein of unknown function, similar to alpha-D-glucosidases; transcriptionally activated by both Pdr8p and Yrm1p, along with transporters and other genes involved in the pleiotropic drug resistance (PDR) phenomenon |
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| YLL052C Show fit | 1.12 |
Water channel that mediates the transport of water across cell membranes, only expressed in proliferating cells, controlled by osmotic signals, may be involved in freeze tolerance; disrupted by a stop codon in many S. cerevisiae strains |
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| YER067C-A Show fit | 1.11 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the uncharacterized ORF YER067W |
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| YCR102W-A Show fit | 1.08 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data |
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| YMR082C Show fit | 1.06 |
Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data |
Network of associatons between targets according to the STRING database.
First level regulatory network of CEP3
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.3 | GO:0007129 | synapsis(GO:0007129) |
| 0.0 | 1.2 | GO:0070726 | cell wall assembly(GO:0070726) |
| 0.0 | 1.1 | GO:0006457 | protein folding(GO:0006457) |
| 0.1 | 1.0 | GO:0070086 | ubiquitin-dependent endocytosis(GO:0070086) |
| 0.3 | 0.9 | GO:0000101 | sulfur amino acid transport(GO:0000101) |
| 0.3 | 0.9 | GO:0006003 | fructose 2,6-bisphosphate metabolic process(GO:0006003) |
| 0.2 | 0.9 | GO:0000296 | spermine transport(GO:0000296) |
| 0.1 | 0.8 | GO:0015891 | siderophore transport(GO:0015891) |
| 0.0 | 0.8 | GO:0006633 | fatty acid biosynthetic process(GO:0006633) |
| 0.2 | 0.7 | GO:0006103 | 2-oxoglutarate metabolic process(GO:0006103) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.2 | GO:0045121 | membrane raft(GO:0045121) membrane microdomain(GO:0098857) |
| 0.3 | 0.9 | GO:0030428 | cell septum(GO:0030428) |
| 0.1 | 0.8 | GO:0045239 | tricarboxylic acid cycle enzyme complex(GO:0045239) |
| 0.0 | 0.7 | GO:0070469 | respiratory chain(GO:0070469) |
| 0.2 | 0.6 | GO:0009331 | glycerol-3-phosphate dehydrogenase complex(GO:0009331) |
| 0.0 | 0.6 | GO:0005887 | integral component of plasma membrane(GO:0005887) |
| 0.0 | 0.6 | GO:0005811 | lipid particle(GO:0005811) |
| 0.1 | 0.5 | GO:0017059 | serine C-palmitoyltransferase complex(GO:0017059) SPOTS complex(GO:0035339) |
| 0.1 | 0.4 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
| 0.1 | 0.4 | GO:0031901 | early endosome membrane(GO:0031901) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 2.9 | GO:0022838 | substrate-specific channel activity(GO:0022838) |
| 0.0 | 1.1 | GO:0016298 | lipase activity(GO:0016298) |
| 0.1 | 1.0 | GO:0031625 | ubiquitin protein ligase binding(GO:0031625) ubiquitin-like protein ligase binding(GO:0044389) |
| 0.0 | 1.0 | GO:0051082 | unfolded protein binding(GO:0051082) |
| 0.3 | 0.9 | GO:0003873 | 6-phosphofructo-2-kinase activity(GO:0003873) |
| 0.2 | 0.9 | GO:0000297 | spermine transmembrane transporter activity(GO:0000297) |
| 0.2 | 0.9 | GO:0000099 | sulfur amino acid transmembrane transporter activity(GO:0000099) |
| 0.2 | 0.9 | GO:0015295 | solute:proton symporter activity(GO:0015295) |
| 0.2 | 0.8 | GO:0034318 | alcohol O-acetyltransferase activity(GO:0004026) alcohol O-acyltransferase activity(GO:0034318) |
| 0.2 | 0.7 | GO:0005537 | mannose binding(GO:0005537) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 22.1 | PID FOXM1 PATHWAY | FOXM1 transcription factor network |
| 0.1 | 0.4 | PID NOTCH PATHWAY | Notch signaling pathway |
| 0.1 | 0.3 | PID IL4 2PATHWAY | IL4-mediated signaling events |
| 0.1 | 0.2 | PID P38 ALPHA BETA DOWNSTREAM PATHWAY | Signaling mediated by p38-alpha and p38-beta |
| 0.1 | 0.2 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
| 0.0 | 0.1 | PID EPHA2 FWD PATHWAY | EPHA2 forward signaling |
| 0.0 | 0.1 | PID INTEGRIN A4B1 PATHWAY | Alpha4 beta1 integrin signaling events |
| 0.0 | 0.1 | PID ERBB4 PATHWAY | ErbB4 signaling events |
| 0.0 | 0.1 | PID ATM PATHWAY | ATM pathway |
| 0.0 | 0.1 | PID FANCONI PATHWAY | Fanconi anemia pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 22.1 | REACTOME CHONDROITIN SULFATE BIOSYNTHESIS | Genes involved in Chondroitin sulfate biosynthesis |
| 0.1 | 0.5 | REACTOME GLYCOLYSIS | Genes involved in Glycolysis |
| 0.1 | 0.5 | REACTOME GLUCOSE METABOLISM | Genes involved in Glucose metabolism |
| 0.1 | 0.4 | REACTOME ETHANOL OXIDATION | Genes involved in Ethanol oxidation |
| 0.1 | 0.3 | REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS | Genes involved in Glycerophospholipid biosynthesis |
| 0.1 | 0.2 | REACTOME MYD88 MAL CASCADE INITIATED ON PLASMA MEMBRANE | Genes involved in MyD88:Mal cascade initiated on plasma membrane |
| 0.1 | 0.2 | REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE | Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle |
| 0.0 | 0.2 | REACTOME FATTY ACID TRIACYLGLYCEROL AND KETONE BODY METABOLISM | Genes involved in Fatty acid, triacylglycerol, and ketone body metabolism |
| 0.0 | 0.2 | REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN | Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein |
| 0.1 | 0.1 | REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS | Genes involved in Phase 1 - Functionalization of compounds |