Gene Symbol | Gene ID | Gene Info |
---|---|---|
CAD1
|
S000002831 | AP-1-like basic leucine zipper (bZIP) transcriptional activator |
Promoter | Log-likelihood | Transcript | Gene | Gene Info |
---|---|---|---|---|
YPL171C | 15.22 |
OYE3
|
Widely conserved NADPH oxidoreductase containing flavin mononucleotide (FMN), homologous to Oye2p with slight differences in ligand binding and catalytic properties; may be involved in sterol metabolism |
|
YFL055W | 10.04 |
AGP3
|
Low-affinity amino acid permease, may act to supply the cell with amino acids as nitrogen source in nitrogen-poor conditions; transcription is induced under conditions of sulfur limitation; plays a role in regulating Ty1 transposition |
|
YNL195C | 8.88 |
Putative protein of unknown function; shares a promoter with YNL194C; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies |
||
YAR050W | 8.45 |
FLO1
|
Lectin-like protein involved in flocculation, cell wall protein that binds to mannose chains on the surface of other cells, confers floc-forming ability that is chymotrypsin sensitive and heat resistant; similar to Flo5p |
|
YHR139C | 8.00 |
SPS100
|
Protein required for spore wall maturation; expressed during sporulation; may be a component of the spore wall |
|
YOR382W | 7.82 |
FIT2
|
Mannoprotein that is incorporated into the cell wall via a glycosylphosphatidylinositol (GPI) anchor, involved in the retention of siderophore-iron in the cell wall |
|
YOR100C | 7.74 |
CRC1
|
Mitochondrial inner membrane carnitine transporter, required for carnitine-dependent transport of acetyl-CoA from peroxisomes to mitochondria during fatty acid beta-oxidation |
|
YLR296W | 7.67 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data |
||
YHL040C | 7.51 |
ARN1
|
Transporter, member of the ARN family of transporters that specifically recognize siderophore-iron chelates; responsible for uptake of iron bound to ferrirubin, ferrirhodin, and related siderophores |
|
YCR007C | 7.39 |
Putative integral membrane protein, member of DUP240 gene family; YCR007C is not an essential gene |
||
YDR277C | 7.29 |
MTH1
|
Negative regulator of the glucose-sensing signal transduction pathway, required for repression of transcription by Rgt1p; interacts with Rgt1p and the Snf3p and Rgt2p glucose sensors; phosphorylated by Yck1p, triggering Mth1p degradation |
|
YKL086W | 7.21 |
SRX1
|
Sulfiredoxin, contributes to oxidative stress resistance by reducing cysteine-sulfinic acid groups in the peroxiredoxins Tsa1p and Ahp1p that are formed upon exposure to oxidants; conserved in higher eukaryotes |
|
YKL071W | 7.14 |
Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm |
||
YIL057C | 6.91 |
Putative protein of unknown function; expression induced under carbon limitation and repressed under high glucose |
||
YAR047C | 6.81 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data |
||
YLL053C | 6.74 |
Putative protein; in the Sigma 1278B strain background YLL053C is contiguous with AQY2 which encodes an aquaporin |
||
YLR402W | 6.68 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data |
||
YNR034W-A | 6.43 |
Putative protein of unknown function; expression is regulated by Msn2p/Msn4p |
||
YLR403W | 6.34 |
SFP1
|
Transcription factor that controls expression of many ribosome biogenesis genes in response to nutrients and stress, regulates G2/M transitions during mitotic cell cycle and DNA-damage response, involved in cell size modulation |
|
YLL052C | 5.99 |
AQY2
|
Water channel that mediates the transport of water across cell membranes, only expressed in proliferating cells, controlled by osmotic signals, may be involved in freeze tolerance; disrupted by a stop codon in many S. cerevisiae strains |
|
YLR295C | 5.80 |
ATP14
|
Subunit h of the F0 sector of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis |
|
YDR542W | 5.53 |
PAU10
|
Hypothetical protein |
|
YPL223C | 5.50 |
GRE1
|
Hydrophilin of unknown function; stress induced (osmotic, ionic, oxidative, heat shock and heavy metals); regulated by the HOG pathway |
|
YKL103C | 5.33 |
LAP4
|
Vacuolar aminopeptidase, often used as a marker protein in studies of autophagy and cytosol to vacuole targeting (CVT) pathway |
|
YOR120W | 5.26 |
GCY1
|
Putative NADP(+) coupled glycerol dehydrogenase, proposed to be involved in an alternative pathway for glycerol catabolism; member of the aldo-keto reductase (AKR) family |
|
YDL204W | 5.16 |
RTN2
|
Protein of unknown function; has similarity to mammalian reticulon proteins; member of the RTNLA (reticulon-like A) subfamily |
|
YOR152C | 4.95 |
Putative protein of unknown function; has no similarity to any known protein; YOR152C is not an essential gene |
||
YOR072W | 4.74 |
Dubious open reading frame unlikely to encode a protein, based on experimental and comparative sequence data; partially overlaps the dubious gene YOR072W-A; diploid deletion strains are methotrexate, paraquat and wortmannin sensitive |
||
YKL102C | 4.72 |
Dubious open reading frame unlikely to encode a functional protein; deletion confers sensitivity to citric acid; predicted protein would include a thiol-disulfide oxidoreductase active site |
||
YJL103C | 4.70 |
GSM1
|
Putative zinc cluster protein of unknown function; proposed to be involved in the regulation of energy metabolism, based on patterns of expression and sequence analysis |
|
YKL162C | 4.63 |
Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the mitochondrion |
||
YNL025C | 4.55 |
SSN8
|
Cyclin-like component of the RNA polymerase II holoenzyme, involved in phosphorylation of the RNA polymerase II C-terminal domain; involved in glucose repression and telomere maintenance |
|
YNL125C | 4.51 |
ESBP6
|
Protein with similarity to monocarboxylate permeases, appears not to be involved in transport of monocarboxylates such as lactate, pyruvate or acetate across the plasma membrane |
|
YHR008C | 4.50 |
SOD2
|
Mitochondrial superoxide dismutase, protects cells against oxygen toxicity; phosphorylated |
|
YGR225W | 4.48 |
AMA1
|
Activator of meiotic anaphase promoting complex (APC/C); Cdc20p family member; required for initiation of spore wall assembly; required for Clb1p degradation during meiosis |
|
YDR453C | 4.28 |
TSA2
|
Stress inducible cytoplasmic thioredoxin peroxidase; cooperates with Tsa1p in the removal of reactive oxygen, nitrogen and sulfur species using thioredoxin as hydrogen donor; deletion enhances the mutator phenotype of tsa1 mutants |
|
YJR138W | 4.25 |
IML1
|
Protein of unknown function, green fluorescent protein (GFP)-fusion protein localizes to the vacuolar membrane |
|
YAL002W | 4.20 |
VPS8
|
Membrane-associated protein that interacts with Vps21p to facilitate soluble vacuolar protein localization; component of the CORVET complex; required for localization and trafficking of the CPY sorting receptor; contains RING finger motif |
|
YAL062W | 4.02 |
GDH3
|
NADP(+)-dependent glutamate dehydrogenase, synthesizes glutamate from ammonia and alpha-ketoglutarate; rate of alpha-ketoglutarate utilization differs from Gdh1p; expression regulated by nitrogen and carbon sources |
|
YLR149C | 4.01 |
Putative protein of unknown function; YLR149C is not an essential gene |
||
YGR065C | 3.89 |
VHT1
|
High-affinity plasma membrane H+-biotin (vitamin H) symporter; mutation results in fatty acid auxotrophy; 12 transmembrane domain containing major facilitator subfamily member; mRNA levels negatively regulated by iron deprivation and biotin |
|
YOR072W-A | 3.86 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the uncharacterized ORF YOR072W; originally identified by fungal homology and RT-PCR |
||
YER014C-A | 3.85 |
BUD25
|
Protein involved in bud-site selection; diploid mutants display a random budding pattern instead of the wild-type bipolar pattern |
|
YML131W | 3.84 |
Putative protein of unknown function with similarity to oxidoreductases; HOG1 and SKO1-dependent mRNA expression is induced after osmotic shock; GFP-fusion protein localizes to the cytoplasm and is induced by the DNA-damaging agent MMS |
||
YOR071C | 3.77 |
NRT1
|
High-affinity nicotinamide riboside transporter; also transports thiamine with low affinity; shares sequence similarity with Thi7p and Thi72p; proposed to be involved in 5-fluorocytosine sensitivity |
|
YGR144W | 3.76 |
THI4
|
Thiazole synthase, catalyzes formation of the thiazole moiety of thiamin pyrophosphate; required for thiamine biosynthesis and for mitochondrial genome stability |
|
YDR055W | 3.59 |
PST1
|
Cell wall protein that contains a putative GPI-attachment site; secreted by regenerating protoplasts; up-regulated by activation of the cell integrity pathway, as mediated by Rlm1p; upregulated by cell wall damage via disruption of FKS1 |
|
YHR048W | 3.57 |
YHK8
|
Presumed antiporter of the DHA1 family of multidrug resistance transporters; contains 12 predicted transmembrane spans; expression of gene is up-regulated in cells exhibiting reduced susceptibility to azoles |
|
YMR107W | 3.50 |
SPG4
|
Protein required for survival at high temperature during stationary phase; not required for growth on nonfermentable carbon sources |
|
YFL052W | 3.49 |
Putative zinc cluster protein that contains a DNA binding domain; null mutant sensitive to calcofluor white, low osmolarity and heat, suggesting a role for YFL052Wp in cell wall integrity |
||
YJR137C | 3.48 |
ECM17
|
Sulfite reductase beta subunit, involved in amino acid biosynthesis, transcription repressed by methionine |
|
YLL060C | 3.40 |
GTT2
|
Glutathione S-transferase capable of homodimerization; functional overlap with Gtt2p, Grx1p, and Grx2p |
|
YLR297W | 3.39 |
Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole; YLR297W is not an essential gene; induced by treatment with 8-methoxypsoralen and UVA irradiation |
||
YBR008C | 3.36 |
FLR1
|
Plasma membrane multidrug transporter of the major facilitator superfamily, involved in efflux of fluconazole, diazaborine, benomyl, methotrexate, and other drugs |
|
YDR258C | 3.31 |
HSP78
|
Oligomeric mitochondrial matrix chaperone that cooperates with Ssc1p in mitochondrial thermotolerance after heat shock; prevents the aggregation of misfolded matrix proteins; component of the mitochondrial proteolysis system |
|
YPR078C | 3.23 |
Putative protein of unknown function; possible role in DNA metabolism and/or in genome stability; expression is heat-inducible |
||
YOL159C | 3.18 |
Soluble protein of unknown function; deletion mutants are viable and have elevated levels of Ty1 retrotransposition and Ty1 cDNA |
||
YDL218W | 3.17 |
Putative protein of unknown function; YDL218W transcription is regulated by Azf1p and induced by starvation and aerobic conditions |
||
YBR117C | 3.14 |
TKL2
|
Transketolase, similar to Tkl1p; catalyzes conversion of xylulose-5-phosphate and ribose-5-phosphate to sedoheptulose-7-phosphate and glyceraldehyde-3-phosphate in the pentose phosphate pathway; needed for synthesis of aromatic amino acids |
|
YDR533C | 3.14 |
HSP31
|
Possible chaperone and cysteine protease with similarity to E. coli Hsp31; member of the DJ-1/ThiJ/PfpI superfamily, which includes human DJ-1 involved in Parkinson's disease; exists as a dimer and contains a putative metal-binding site |
|
YDL020C | 3.08 |
RPN4
|
Transcription factor that stimulates expression of proteasome genes; Rpn4p levels are in turn regulated by the 26S proteasome in a negative feedback control mechanism; RPN4 is transcriptionally regulated by various stress responses |
|
YDL243C | 3.05 |
AAD4
|
Putative aryl-alcohol dehydrogenase with similarity to P. chrysosporium aryl-alcohol dehydrogenase, involved in the oxidative stress response |
|
YBL060W | 3.02 |
YEL1
|
Guanine nucleotide exchange factor specific for Arf3p; localized to the bud neck and tip; required for localization of Arf3p to the bud neck and tip |
|
YER167W | 3.00 |
BCK2
|
Protein rich in serine and threonine residues involved in protein kinase C signaling pathway, which controls cell integrity; overproduction suppresses pkc1 mutations |
|
YNR063W | 2.96 |
Putative zinc-cluster protein of unknown function |
||
YJL102W | 2.95 |
MEF2
|
Mitochondrial elongation factor involved in translational elongation |
|
YGL184C | 2.93 |
STR3
|
Cystathionine beta-lyase, converts cystathionine into homocysteine |
|
YER141W | 2.90 |
COX15
|
Protein required for the hydroxylation of heme O to form heme A, which is an essential prosthetic group for cytochrome c oxidase |
|
YEL009C-A | 2.87 |
Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data |
||
YAL018C | 2.83 |
Putative protein of unknown function |
||
YEL008W | 2.81 |
Hypothetical protein predicted to be involved in metabolism |
||
YNL093W | 2.78 |
YPT53
|
GTPase, similar to Ypt51p and Ypt52p and to mammalian rab5; required for vacuolar protein sorting and endocytosis |
|
YLL056C | 2.77 |
Putative protein of unknown function, transcription is activated by paralogous transcription factors Yrm1p and Yrr1p along with genes involved in pleiotropic drug resistance (PDR) phenomenon; YLL056C is not an essential gene |
||
YDR541C | 2.75 |
Putative dihydrokaempferol 4-reductase |
||
YOR065W | 2.73 |
CYT1
|
Cytochrome c1, component of the mitochondrial respiratory chain; expression is regulated by the heme-activated, glucose-repressed Hap2p/3p/4p/5p CCAAT-binding complex |
|
YFL051C | 2.73 |
Putative protein of unknown function; YFL051C is not an essential gene |
||
YPR111W | 2.72 |
DBF20
|
Ser/Thr kinase involved in late nuclear division, one of the mitotic exit network (MEN) proteins; necessary for the execution of cytokinesis |
|
YEL009C | 2.70 |
GCN4
|
Transcriptional activator of amino acid biosynthetic genes in response to amino acid starvation; expression is tightly regulated at both the transcriptional and translational levels |
|
YLR247C | 2.69 |
IRC20
|
Putative helicase; localizes to the mitochondrion and the nucleus; YLR247C is not an essential gene; null mutant displays increased levels of spontaneous Rad52p foci |
|
YOL050C | 2.69 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps verified gene GAL11; deletion confers sensitivity to 4-(N-(S-glutathionylacetyl)amino) phenylarsenoxide (GSAO) |
||
YOL025W | 2.68 |
LAG2
|
Protein involved in determination of longevity; LAG2 gene is preferentially expressed in young cells; overexpression extends the mean and maximum life span of cells |
|
YCL048W | 2.61 |
SPS22
|
Protein of unknown function, redundant with Sps2p for the organization of the beta-glucan layer of the spore wall |
|
YJL163C | 2.60 |
Putative protein of unknown function |
||
YJL100W | 2.60 |
LSB6
|
Type II phosphatidylinositol 4-kinase that binds Las17p, which is a homolog of human Wiskott-Aldrich Syndrome protein involved in actin patch assembly and actin polymerization |
|
YHR015W | 2.58 |
MIP6
|
Putative RNA-binding protein, interacts with Mex67p, which is a component of the nuclear pore involved in nuclear mRNA export |
|
YPR036W-A | 2.57 |
Protein of unknown function; transcription is regulated by Pdr1p |
||
YPR023C | 2.54 |
EAF3
|
Esa1p-associated factor, nonessential component of the NuA4 acetyltransferase complex, homologous to Drosophila dosage compensation protein MSL3; plays a role in regulating Ty1 transposition |
|
YOR227W | 2.52 |
Protein of unknown function that may interact with ribosomes, based on co-purification experiments; authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies |
||
YOL128C | 2.52 |
YGK3
|
Protein kinase related to mammalian glycogen synthase kinases of the GSK-3 family; GSK-3 homologs (Mck1p, Rim11p, Mrk1p, Ygk3p) are involved in control of Msn2p-dependent transcription of stress responsive genes and in protein degradation |
|
YDL214C | 2.49 |
PRR2
|
Serine/threonine protein kinase that inhibits pheromone induced signalling downstream of MAPK, possibly at the level of the Ste12p transcription factor |
|
YAL067C | 2.48 |
SEO1
|
Putative permease, member of the allantoate transporter subfamily of the major facilitator superfamily; mutation confers resistance to ethionine sulfoxide |
|
YGL114W | 2.46 |
Putative protein of unknown function; predicted member of the oligopeptide transporter (OPT) family of membrane transporters |
||
YLR299W | 2.45 |
ECM38
|
Gamma-glutamyltranspeptidase, major glutathione-degrading enzyme; involved in detoxification of electrophilic xenobiotics; expression induced mainly by nitrogen starvation |
|
YOR228C | 2.40 |
Protein of unknown function, localized to the mitochondrial outer membrane |
||
YGL090W | 2.39 |
LIF1
|
Component of the DNA ligase IV complex that mediates nonhomologous end joining in DNA double-strand break repair; physically interacts with Dnl4p and Nej1p; homologous to mammalian XRCC4 protein |
|
YPR013C | 2.35 |
Putative zinc finger protein; YPR013C is not an essential gene |
||
YAL039C | 2.34 |
CYC3
|
Cytochrome c heme lyase (holocytochrome c synthase), attaches heme to apo-cytochrome c (Cyc1p or Cyc7p) in the mitochondrial intermembrane space; human ortholog may have a role in microphthalmia with linear skin defects (MLS) |
|
YHR102W | 2.31 |
KIC1
|
Protein kinase of the PAK/Ste20 kinase family, required for cell integrity possibly through regulating 1,6-beta-glucan levels in the wall; physically interacts with Cdc31p (centrin), which is a component of the spindle pole body |
|
YCR021C | 2.30 |
HSP30
|
Hydrophobic plasma membrane localized, stress-responsive protein that negatively regulates the H(+)-ATPase Pma1p; induced by heat shock, ethanol treatment, weak organic acid, glucose limitation, and entry into stationary phase |
|
YKL044W | 2.29 |
Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data |
||
YER147C | 2.26 |
SCC4
|
Subunit of cohesin loading factor (Scc2p-Scc4p), a complex required for the loading of cohesin complexes onto chromosomes; involved in establishing sister chromatid cohesion during double-strand break repair via phosphorylated histone H2AX |
|
YDR169C | 2.23 |
STB3
|
Protein that binds Sin3p in a two-hybrid assay |
|
YNL331C | 2.21 |
AAD14
|
Putative aryl-alcohol dehydrogenase with similarity to P. chrysosporium aryl-alcohol dehydrogenase; mutational analysis has not yet revealed a physiological role |
|
YHR006W | 2.20 |
STP2
|
Transcription factor, activated by proteolytic processing in response to signals from the SPS sensor system for external amino acids; activates transcription of amino acid permease genes |
|
YPL222W | 2.19 |
FMP40
|
Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies |
|
YOR387C | 2.19 |
Putative protein of unknown function; regulated by the metal-responsive Aft1p transcription factor; highly inducible in zinc-depleted conditions; localizes to the soluble fraction |
||
YML087C | 2.16 |
AIM33
|
Putative protein of unknown function; highly conserved across species and orthologous to human CYB5R4; null mutant shows increased frequency of mitochondrial genome loss (petite formation) and severe growth defect in minimal glycerol media |
|
YBR047W | 2.13 |
FMP23
|
Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies |
|
YCL017C | 2.12 |
NFS1
|
Cysteine desulfurase involved in iron-sulfur cluster (Fe/S) biogenesis; required for the post-transcriptional thio-modification of mitochondrial and cytoplasmic tRNAs; essential protein located predominantly in mitochondria |
|
YAL054C | 2.12 |
ACS1
|
Acetyl-coA synthetase isoform which, along with Acs2p, is the nuclear source of acetyl-coA for histone acetlyation; expressed during growth on nonfermentable carbon sources and under aerobic conditions |
|
YOR223W | 2.11 |
Putative protein of unknown function |
||
YLR135W | 2.10 |
SLX4
|
Subunit of a complex, with Slx1p, that hydrolyzes 5' branches from duplex DNA in response to stalled or converging replication forks; function overlaps with that of Sgs1p-Top3p |
|
YGL180W | 2.08 |
ATG1
|
Protein serine/threonine kinase required for vesicle formation in autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; structurally required for pre-autophagosome formation; during autophagy forms a complex with Atg13p and Atg17p |
|
YLL055W | 2.08 |
YCT1
|
High-affinity cysteine-specific transporter with similarity to the Dal5p family of transporters; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; YCT1 is not an essential gene |
|
YKL217W | 2.07 |
JEN1
|
Lactate transporter, required for uptake of lactate and pyruvate; phosphorylated; expression is derepressed by transcriptional activator Cat8p during respiratory growth, and repressed in the presence of glucose, fructose, and mannose |
|
YGR258C | 2.05 |
RAD2
|
Single-stranded DNA endonuclease, cleaves single-stranded DNA during nucleotide excision repair to excise damaged DNA; subunit of Nucleotide Excision Repair Factor 3 (NEF3); homolog of human XPG protein |
|
YHR139C-A | 2.03 |
Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data |
||
YLR307C-A | 2.01 |
Putative protein of unknown function |
||
YHL036W | 2.01 |
MUP3
|
Low affinity methionine permease, similar to Mup1p |
|
YOL084W | 1.98 |
PHM7
|
Protein of unknown function, expression is regulated by phosphate levels; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery and vacuole |
|
YEL010W | 1.96 |
Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data |
||
YKL148C | 1.94 |
SDH1
|
Flavoprotein subunit of succinate dehydrogenase (Sdh1p, Sdh2p, Sdh3p, Sdh4p), which couples the oxidation of succinate to the transfer of electrons to ubiquinone |
|
YPR169W-A | 1.93 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps two other dubious ORFs: YPR170C and YPR170W-B |
||
YJL020C | 1.91 |
BBC1
|
Protein possibly involved in assembly of actin patches; interacts with an actin assembly factor Las17p and with the SH3 domains of Type I myosins Myo3p and Myo5p; localized predominantly to cortical actin patches |
|
YIL059C | 1.91 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the uncharacterized ORF YIL060W |
||
YJL213W | 1.91 |
Protein of unknown function that may interact with ribosomes; periodically expressed during the yeast metabolic cycle; phosphorylated in vitro by the mitotic exit network (MEN) kinase complex, Dbf2p/Mob1p |
||
YMR034C | 1.90 |
Putative transporter, member of the SLC10 carrier family; identified in a transposon mutagenesis screen as a gene involved in azole resistance; YMR034C is not an essential gene |
||
YKR067W | 1.90 |
GPT2
|
Glycerol-3-phosphate/dihydroxyacetone phosphate dual substrate-specific sn-1 acyltransferase located in lipid particles and the ER; involved in the stepwise acylation of glycerol-3-phosphate and dihydroxyacetone in lipid biosynthesis |
|
YCR068W | 1.89 |
ATG15
|
Lipase, required for intravacuolar lysis of autophagosomes; located in the endoplasmic reticulum membrane and targeted to intravacuolar vesicles during autophagy via the multivesicular body (MVB) pathway |
|
YGL089C | 1.87 |
MF(ALPHA)2
|
Mating pheromone alpha-factor, made by alpha cells; interacts with mating type a cells to induce cell cycle arrest and other responses leading to mating; also encoded by MF(ALPHA)1, which is more highly expressed than MF(ALPHA)2 |
|
YPR005C | 1.85 |
HAL1
|
Cytoplasmic protein involved in halotolerance; decreases intracellular Na+ (via Ena1p) and increases intracellular K+ by decreasing efflux; expression repressed by Ssn6p-Tup1p and Sko1p and induced by NaCl, KCl, and sorbitol through Gcn4p |
|
YBL049W | 1.84 |
MOH1
|
Protein of unknown function, has homology to kinase Snf7p; not required for growth on nonfermentable carbon sources; essential for viability in stationary phase |
|
YKL163W | 1.83 |
PIR3
|
O-glycosylated covalently-bound cell wall protein required for cell wall stability; expression is cell cycle regulated, peaking in M/G1 and also subject to regulation by the cell integrity pathway |
|
YPL164C | 1.81 |
MLH3
|
Protein involved in DNA mismatch repair and crossing-over during meiotic recombination; forms a complex with Mlh1p; mammalian homolog is implicated mammalian microsatellite instability |
|
YOR011W-A | 1.80 |
Putative protein of unknown function |
||
YGR233C | 1.78 |
PHO81
|
Cyclin-dependent kinase (CDK) inhibitor, regulates Pho80p-Pho85p and Pcl7p-Pho85p cyclin-CDK complexes in response to phosphate levels; inhibitory activity for Pho80p-Pho85p requires myo-D-inositol heptakisphosphate (IP7) generated by Vip1p |
|
YBL039W-B | 1.75 |
Putative protein of unknown function |
||
YOR347C | 1.74 |
PYK2
|
Pyruvate kinase that appears to be modulated by phosphorylation; PYK2 transcription is repressed by glucose, and Pyk2p may be active under low glycolytic flux |
|
YLR346C | 1.74 |
Putative protein of unknown function found in mitochondria; expression is regulated by transcription factors involved in pleiotropic drug resistance, Pdr1p and Yrr1p; YLR346C is not an essential gene |
||
YBR046C | 1.72 |
ZTA1
|
Zeta-crystallin homolog, found in the cytoplasm and nucleus; has similarity to E. coli quinone oxidoreductase and to human zeta-crystallin, which has quinone oxidoreductase activity |
|
YMR175W | 1.71 |
SIP18
|
Protein of unknown function whose expression is induced by osmotic stress |
|
YLR054C | 1.71 |
OSW2
|
Protein of unknown function proposed to be involved in the assembly of the spore wall |
|
YMR103C | 1.70 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data |
||
YOR303W | 1.69 |
CPA1
|
Small subunit of carbamoyl phosphate synthetase, which catalyzes a step in the synthesis of citrulline, an arginine precursor; translationally regulated by an attenuator peptide encoded by YOR302W within the CPA1 mRNA 5'-leader |
|
YJR091C | 1.69 |
JSN1
|
Member of the Puf family of RNA-binding proteins, interacts with mRNAs encoding membrane-associated proteins; overexpression suppresses a tub2-150 mutation and causes increased sensitivity to benomyl in wild-type cells |
|
YAL061W | 1.69 |
BDH2
|
Putative medium-chain alcohol dehydrogenase with similarity to BDH1; transcription induced by constitutively active PDR1 and PDR3; BDH2 is an essential gene |
|
YKL161C | 1.68 |
Protein kinase implicated in the Slt2p mitogen-activated (MAP) kinase signaling pathway; associates with Rlm1p |
||
YNL176C | 1.66 |
Cell cycle-regulated gene of unknown function, promoter bound by Fkh2p |
||
YBR208C | 1.64 |
DUR1,2
|
Urea amidolyase, contains both urea carboxylase and allophanate hydrolase activities, degrades urea to CO2 and NH3; expression sensitive to nitrogen catabolite repression and induced by allophanate, an intermediate in allantoin degradation |
|
YPR201W | 1.62 |
ARR3
|
Arsenite transporter of the plasma membrane, required for resistance to arsenic compounds; transcription is activated by Arr1p in the presence of arsenite |
|
YKL016C | 1.61 |
ATP7
|
Subunit d of the stator stalk of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis |
|
YEL049W | 1.60 |
PAU2
|
Part of 23-member seripauperin multigene family encoded mainly in subtelomeric regions, active during alcoholic fermentation, regulated by anaerobiosis, negatively regulated by oxygen, repressed by heme |
|
YJL199C | 1.60 |
MBB1
|
Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; protein detected in large-scale protein-protein interaction studies |
|
YEL007W | 1.60 |
Putative protein with sequence similarity to S. pombe gti1+ (gluconate transport inducer 1) |
||
YIR027C | 1.59 |
DAL1
|
Allantoinase, converts allantoin to allantoate in the first step of allantoin degradation; expression sensitive to nitrogen catabolite repression |
|
YDL124W | 1.59 |
NADPH-dependent alpha-keto amide reductase; reduces aromatic alpha-keto amides, aliphatic alpha-keto esters, and aromatic alpha-keto esters; member of the aldo-keto reductase (AKR) family |
||
YIL107C | 1.58 |
PFK26
|
6-phosphofructo-2-kinase, inhibited by phosphoenolpyruvate and sn-glycerol 3-phosphate, has negligible fructose-2,6-bisphosphatase activity, transcriptional regulation involves protein kinase A |
|
YNL197C | 1.57 |
WHI3
|
RNA binding protein that sequesters CLN3 mRNA in cytoplasmic foci; cytoplasmic retention factor for Cdc28p and associated cyclins; regulates cell fate and dose-dependently regulates the critical cell size required for passage through Start |
|
YJR150C | 1.57 |
DAN1
|
Cell wall mannoprotein with similarity to Tir1p, Tir2p, Tir3p, and Tir4p; expressed under anaerobic conditions, completely repressed during aerobic growth |
|
YFL019C | 1.54 |
Dubious open reading frame unlikely to encode a protein; YFL019C is not an essential gene |
||
YHR101C | 1.54 |
BIG1
|
Integral membrane protein of the endoplasmic reticulum, required for normal content of cell wall beta-1,6-glucan |
|
YHR199C | 1.53 |
AIM46
|
Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; null mutant displays increased frequency of mitochondrial genome loss (petite formation) |
|
YMR118C | 1.52 |
Protein of unknown function with similarity to succinate dehydrogenase cytochrome b subunit; YMR118C is not an essential gene |
||
YLR312C | 1.52 |
QNQ1
|
Protein of unknown function; null mutant quiescent and non-quiescent cells exhibit reduced reproductive capacity |
|
YNL094W | 1.52 |
APP1
|
Protein of unknown function, interacts with Rvs161p and Rvs167p; computational analysis of protein-protein interactions in large-scale studies suggests a possible role in actin filament organization |
|
YLR334C | 1.51 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps a stand-alone long terminal repeat sequence whose presence indicates a retrotransposition event occurred here |
||
YDR114C | 1.51 |
Putative protein of unknown function; deletion mutant exhibits poor growth at elevated pH and calcium |
||
YER187W | 1.50 |
Putative protein of unknown function; induced in respiratory-deficient cells |
||
YGR110W | 1.50 |
Putative protein of unknown function; transcription is increased in response to genotoxic stress; plays a role in restricting Ty1 transposition |
||
YKL043W | 1.48 |
PHD1
|
Transcriptional activator that enhances pseudohyphal growth; regulates expression of FLO11, an adhesin required for pseudohyphal filament formation; similar to StuA, an A. nidulans developmental regulator; potential Cdc28p substrate |
|
YJR160C | 1.47 |
MPH3
|
Alpha-glucoside permease, transports maltose, maltotriose, alpha-methylglucoside, and turanose; identical to Mph2p; encoded in a subtelomeric position in a region likely to have undergone duplication |
|
YPL061W | 1.47 |
ALD6
|
Cytosolic aldehyde dehydrogenase, activated by Mg2+ and utilizes NADP+ as the preferred coenzyme; required for conversion of acetaldehyde to acetate; constitutively expressed; locates to the mitochondrial outer surface upon oxidative stress |
|
YBR128C | 1.46 |
ATG14
|
Autophagy-specific subunit of phosphatidylinositol 3-kinase complex I (with Vps34p, Vps15p, and Vps30p); Atg14p targets complex I to the pre-autophagosomal structure (PAS); required for localizing additional ATG proteins to the PAS |
|
YBR054W | 1.45 |
YRO2
|
Putative protein of unknown function; the authentic, non-tagged protein is detected in a phosphorylated state in highly purified mitochondria in high-throughput studies; transcriptionally regulated by Haa1p |
|
YDR306C | 1.45 |
F-box protein of unknown function; interacts with Sgt1p via a Leucine-Rich Repeat (LRR) domain |
||
YPR117W | 1.44 |
Putative protein of unknown function |
||
YMR169C | 1.44 |
ALD3
|
Cytoplasmic aldehyde dehydrogenase, involved in beta-alanine synthesis; uses NAD+ as the preferred coenzyme; very similar to Ald2p; expression is induced by stress and repressed by glucose |
|
YOR290C | 1.43 |
SNF2
|
Catalytic subunit of the SWI/SNF chromatin remodeling complex involved in transcriptional regulation; contains DNA-stimulated ATPase activity; functions interdependently in transcriptional activation with Snf5p and Snf6p |
|
YPL271W | 1.41 |
ATP15
|
Epsilon subunit of the F1 sector of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis; phosphorylated |
|
YBR179C | 1.41 |
FZO1
|
Mitochondrial integral membrane protein involved in mitochondrial fusion and maintenance of the mitochondrial genome; contains N-terminal GTPase domain |
|
YLR375W | 1.40 |
STP3
|
Zinc-finger protein of unknown function, possibly involved in pre-tRNA splicing and in uptake of branched-chain amino acids |
|
YKL087C | 1.40 |
CYT2
|
Cytochrome c1 heme lyase, involved in maturation of cytochrome c1, which is a subunit of the mitochondrial ubiquinol-cytochrome-c reductase; links heme covalently to apocytochrome c1 |
|
YLR080W | 1.39 |
EMP46
|
Integral membrane component of endoplasmic reticulum-derived COPII-coated vesicles, which function in ER to Golgi transport |
|
YJR095W | 1.39 |
SFC1
|
Mitochondrial succinate-fumarate transporter, transports succinate into and fumarate out of the mitochondrion; required for ethanol and acetate utilization |
|
YML116W-A | 1.38 |
Putative protein of unknown function |
||
YAL017W | 1.38 |
PSK1
|
One of two (see also PSK2) PAS domain containing S/T protein kinases; coordinately regulates protein synthesis and carbohydrate metabolism and storage in response to a unknown metabolite that reflects nutritional status |
|
YMR084W | 1.36 |
Putative protein of unknown function; YMR084W and adjacent ORF YMR085W are merged in related strains |
||
YKL124W | 1.36 |
SSH4
|
Specificity factor required for Rsp5p-dependent ubiquitination and sorting of cargo proteins at the multivesicular body; identified as a high-copy suppressor of a SHR3 deletion, increasing steady-state levels of amino acid permeases |
|
YCL001W-B | 1.35 |
Putative protein of unknown function; identified by homology |
||
YOR192C | 1.34 |
THI72
|
Transporter of thiamine or related compound; shares sequence similarity with Thi7p |
|
YJL101C | 1.34 |
GSH1
|
Gamma glutamylcysteine synthetase catalyzes the first step in glutathione (GSH) biosynthesis; expression induced by oxidants, cadmium, and mercury |
|
YIL017C | 1.34 |
VID28
|
Protein involved in proteasome-dependent catabolite degradation of fructose-1,6-bisphosphatase (FBPase); localized to the nucleus and the cytoplasm |
|
YBL101C | 1.33 |
ECM21
|
Non-essential protein of unknown function; promoter contains several Gcn4p binding elements |
|
YLR374C | 1.33 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the uncharacterized ORF STP3/YLR375W |
||
YGR053C | 1.32 |
Putative protein of unknown function |
||
YOR394W | 1.32 |
PAU21
|
Hypothetical protein |
|
YOR208W | 1.31 |
PTP2
|
Phosphotyrosine-specific protein phosphatase involved in the inactivation of mitogen-activated protein kinase (MAPK) during osmolarity sensing; dephosporylates Hog1p MAPK and regulates its localization; localized to the nucleus |
|
YOR192C-C | 1.30 |
Putative protein of unknown function; identified by expression profiling and mass spectrometry |
||
YDL182W | 1.30 |
LYS20
|
Homocitrate synthase isozyme, catalyzes the condensation of acetyl-CoA and alpha-ketoglutarate to form homocitrate, which is the first step in the lysine biosynthesis pathway; highly similar to the other isozyme, Lys21p |
|
YKL115C | 1.29 |
Dubious open reading frame, unlikely to encode a protein; partially overlaps the verified gene PRR1 |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.9 | 15.5 | GO:0015891 | siderophore transport(GO:0015891) |
1.9 | 3.8 | GO:0072353 | cellular age-dependent response to reactive oxygen species(GO:0072353) |
1.8 | 10.8 | GO:0000501 | flocculation(GO:0000128) flocculation via cell wall protein-carbohydrate interaction(GO:0000501) |
1.8 | 5.3 | GO:0042843 | D-xylose catabolic process(GO:0042843) |
1.7 | 5.1 | GO:0015888 | thiamine transport(GO:0015888) |
1.5 | 4.6 | GO:0043335 | protein unfolding(GO:0043335) |
1.3 | 1.3 | GO:0001315 | age-dependent response to reactive oxygen species(GO:0001315) |
1.2 | 3.7 | GO:0017006 | protein-heme linkage(GO:0017003) protein-tetrapyrrole linkage(GO:0017006) cytochrome c-heme linkage(GO:0018063) |
1.2 | 3.6 | GO:0019676 | ammonia assimilation cycle(GO:0019676) |
1.1 | 6.6 | GO:0060963 | positive regulation of ribosomal protein gene transcription from RNA polymerase II promoter(GO:0060963) |
1.0 | 2.1 | GO:0000736 | double-strand break repair via single-strand annealing, removal of nonhomologous ends(GO:0000736) |
1.0 | 3.1 | GO:0010513 | positive regulation of phosphatidylinositol biosynthetic process(GO:0010513) |
1.0 | 2.1 | GO:0000101 | sulfur amino acid transport(GO:0000101) neutral amino acid transport(GO:0015804) |
1.0 | 3.1 | GO:0097201 | negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201) |
1.0 | 5.1 | GO:0043954 | cellular component maintenance(GO:0043954) |
1.0 | 5.9 | GO:0042407 | cristae formation(GO:0042407) |
0.9 | 2.7 | GO:0046160 | heme a biosynthetic process(GO:0006784) heme a metabolic process(GO:0046160) |
0.9 | 2.7 | GO:0010688 | negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter(GO:0010688) |
0.9 | 1.7 | GO:0071462 | response to water(GO:0009415) cellular response to water stimulus(GO:0071462) |
0.8 | 2.5 | GO:0071466 | cellular response to xenobiotic stimulus(GO:0071466) |
0.8 | 3.3 | GO:0019627 | urea metabolic process(GO:0019627) |
0.8 | 3.9 | GO:0051180 | vitamin transport(GO:0051180) |
0.8 | 2.3 | GO:0032780 | negative regulation of ATPase activity(GO:0032780) |
0.8 | 2.3 | GO:0071169 | establishment of protein localization to chromosome(GO:0070199) establishment of protein localization to chromatin(GO:0071169) |
0.7 | 2.9 | GO:0006848 | pyruvate transport(GO:0006848) |
0.6 | 2.5 | GO:0060195 | antisense RNA transcription(GO:0009300) regulation of antisense RNA transcription(GO:0060194) negative regulation of antisense RNA transcription(GO:0060195) |
0.6 | 1.9 | GO:0036257 | multivesicular body organization(GO:0036257) |
0.6 | 3.1 | GO:0033683 | nucleotide-excision repair, DNA incision(GO:0033683) |
0.6 | 3.0 | GO:0070900 | mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864) |
0.6 | 4.7 | GO:0000411 | regulation of transcription by galactose(GO:0000409) positive regulation of transcription by galactose(GO:0000411) |
0.6 | 1.7 | GO:0044109 | cellular alcohol catabolic process(GO:0044109) |
0.5 | 3.3 | GO:0000256 | allantoin metabolic process(GO:0000255) allantoin catabolic process(GO:0000256) |
0.5 | 1.1 | GO:0006075 | (1->3)-beta-D-glucan biosynthetic process(GO:0006075) |
0.5 | 3.7 | GO:0006855 | drug transmembrane transport(GO:0006855) |
0.5 | 1.6 | GO:0006003 | fructose 2,6-bisphosphate metabolic process(GO:0006003) |
0.5 | 1.0 | GO:0061414 | regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter(GO:0035947) positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) regulation of transcription from RNA polymerase II promoter by a nonfermentable carbon source(GO:0061413) positive regulation of transcription from RNA polymerase II promoter by a nonfermentable carbon source(GO:0061414) |
0.5 | 1.0 | GO:0042744 | hydrogen peroxide catabolic process(GO:0042744) |
0.5 | 2.0 | GO:0006740 | NADPH regeneration(GO:0006740) |
0.5 | 0.5 | GO:0042743 | hydrogen peroxide metabolic process(GO:0042743) |
0.5 | 1.9 | GO:0043901 | negative regulation of conjugation(GO:0031135) negative regulation of conjugation with cellular fusion(GO:0031138) negative regulation of multi-organism process(GO:0043901) |
0.5 | 1.9 | GO:0016024 | CDP-diacylglycerol biosynthetic process(GO:0016024) CDP-diacylglycerol metabolic process(GO:0046341) |
0.5 | 1.4 | GO:0015740 | C4-dicarboxylate transport(GO:0015740) |
0.4 | 0.4 | GO:0042819 | pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819) |
0.4 | 1.3 | GO:0042542 | response to hydrogen peroxide(GO:0042542) |
0.4 | 1.3 | GO:0000200 | inactivation of MAPK activity involved in cell wall organization or biogenesis(GO:0000200) regulation of MAPK cascade involved in cell wall organization or biogenesis(GO:1903137) negative regulation of MAPK cascade involved in cell wall organization or biogenesis(GO:1903138) negative regulation of cell wall organization or biogenesis(GO:1903339) |
0.4 | 1.7 | GO:0051444 | negative regulation of ligase activity(GO:0051352) negative regulation of ubiquitin-protein transferase activity(GO:0051444) |
0.4 | 2.2 | GO:0008053 | mitochondrial fusion(GO:0008053) |
0.4 | 10.3 | GO:0006119 | oxidative phosphorylation(GO:0006119) |
0.4 | 0.8 | GO:0033499 | galactose catabolic process via UDP-galactose(GO:0033499) |
0.4 | 2.8 | GO:0061013 | regulation of mRNA catabolic process(GO:0061013) |
0.4 | 1.6 | GO:0051654 | establishment of mitochondrion localization(GO:0051654) |
0.4 | 16.7 | GO:0042244 | ascospore wall assembly(GO:0030476) spore wall assembly(GO:0042244) spore wall biogenesis(GO:0070590) ascospore wall biogenesis(GO:0070591) fungal-type cell wall assembly(GO:0071940) |
0.4 | 0.8 | GO:0000042 | protein targeting to Golgi(GO:0000042) establishment of protein localization to Golgi(GO:0072600) |
0.4 | 1.2 | GO:0006538 | glutamate catabolic process(GO:0006538) |
0.4 | 1.1 | GO:0015847 | putrescine transport(GO:0015847) |
0.4 | 2.2 | GO:0006207 | 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) 'de novo' UMP biosynthetic process(GO:0044205) |
0.4 | 3.3 | GO:0006077 | (1->6)-beta-D-glucan metabolic process(GO:0006077) |
0.4 | 1.1 | GO:0032874 | positive regulation of stress-activated MAPK cascade(GO:0032874) positive regulation of stress-activated protein kinase signaling cascade(GO:0070304) |
0.4 | 1.4 | GO:0006598 | polyamine catabolic process(GO:0006598) |
0.4 | 1.1 | GO:0046039 | GTP biosynthetic process(GO:0006183) GTP metabolic process(GO:0046039) |
0.4 | 9.3 | GO:0003333 | amino acid transmembrane transport(GO:0003333) |
0.4 | 0.7 | GO:0090295 | nitrogen catabolite repression of transcription(GO:0090295) |
0.4 | 1.4 | GO:0015893 | drug transport(GO:0015893) |
0.3 | 2.4 | GO:0045003 | double-strand break repair via synthesis-dependent strand annealing(GO:0045003) |
0.3 | 1.0 | GO:0009106 | lipoate metabolic process(GO:0009106) lipoate biosynthetic process(GO:0009107) |
0.3 | 3.6 | GO:0015986 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
0.3 | 2.5 | GO:0019878 | lysine biosynthetic process via aminoadipic acid(GO:0019878) |
0.3 | 1.2 | GO:0015793 | glycerol transport(GO:0015793) |
0.3 | 3.3 | GO:0015758 | glucose transport(GO:0015758) |
0.3 | 2.7 | GO:0007039 | protein catabolic process in the vacuole(GO:0007039) |
0.3 | 2.7 | GO:0000436 | carbon catabolite activation of transcription from RNA polymerase II promoter(GO:0000436) carbon catabolite activation of transcription(GO:0045991) |
0.3 | 0.9 | GO:0043200 | response to amino acid(GO:0043200) |
0.3 | 1.5 | GO:0032102 | negative regulation of macroautophagy(GO:0016242) negative regulation of response to external stimulus(GO:0032102) negative regulation of response to extracellular stimulus(GO:0032105) negative regulation of response to nutrient levels(GO:0032108) |
0.3 | 2.6 | GO:0070086 | ubiquitin-dependent endocytosis(GO:0070086) |
0.3 | 2.0 | GO:0000023 | maltose metabolic process(GO:0000023) |
0.3 | 0.6 | GO:0042732 | D-xylose metabolic process(GO:0042732) |
0.3 | 1.7 | GO:0007532 | regulation of mating-type specific transcription, DNA-templated(GO:0007532) |
0.3 | 0.8 | GO:0071073 | positive regulation of phospholipid biosynthetic process(GO:0071073) positive regulation of phospholipid metabolic process(GO:1903727) |
0.3 | 1.1 | GO:0051303 | meiotic telomere clustering(GO:0045141) establishment of chromosome localization(GO:0051303) chromosome localization to nuclear envelope involved in homologous chromosome segregation(GO:0090220) |
0.3 | 1.6 | GO:0006085 | acetyl-CoA biosynthetic process(GO:0006085) |
0.3 | 2.9 | GO:0006526 | arginine biosynthetic process(GO:0006526) |
0.3 | 1.0 | GO:2000284 | positive regulation of cellular amino acid biosynthetic process(GO:2000284) |
0.2 | 6.5 | GO:0008219 | apoptotic process(GO:0006915) cell death(GO:0008219) programmed cell death(GO:0012501) |
0.2 | 1.0 | GO:0051865 | protein autoubiquitination(GO:0051865) |
0.2 | 1.5 | GO:0010508 | positive regulation of autophagy(GO:0010508) |
0.2 | 0.7 | GO:0000448 | cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448) |
0.2 | 2.6 | GO:0006895 | Golgi to endosome transport(GO:0006895) |
0.2 | 0.9 | GO:0070933 | histone H3 deacetylation(GO:0070932) histone H4 deacetylation(GO:0070933) |
0.2 | 0.7 | GO:0031335 | regulation of sulfur amino acid metabolic process(GO:0031335) |
0.2 | 3.6 | GO:0009228 | thiamine biosynthetic process(GO:0009228) thiamine-containing compound biosynthetic process(GO:0042724) |
0.2 | 4.5 | GO:0032511 | late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511) |
0.2 | 1.3 | GO:0006097 | glyoxylate cycle(GO:0006097) |
0.2 | 1.0 | GO:0070096 | mitochondrial outer membrane translocase complex assembly(GO:0070096) |
0.2 | 1.0 | GO:0033993 | response to lipid(GO:0033993) response to oleic acid(GO:0034201) response to fatty acid(GO:0070542) cellular response to lipid(GO:0071396) cellular response to fatty acid(GO:0071398) cellular response to oleic acid(GO:0071400) |
0.2 | 0.2 | GO:0071168 | protein localization to chromatin(GO:0071168) |
0.2 | 1.7 | GO:0046685 | response to arsenic-containing substance(GO:0046685) |
0.2 | 0.9 | GO:0006265 | DNA topological change(GO:0006265) |
0.2 | 0.6 | GO:0007070 | negative regulation of transcription during mitosis(GO:0007068) negative regulation of transcription from RNA polymerase II promoter during mitosis(GO:0007070) regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) |
0.2 | 1.2 | GO:0015718 | monocarboxylic acid transport(GO:0015718) |
0.2 | 2.5 | GO:1905037 | autophagosome assembly(GO:0000045) autophagosome organization(GO:1905037) |
0.2 | 2.5 | GO:0006098 | pentose-phosphate shunt(GO:0006098) glyceraldehyde-3-phosphate metabolic process(GO:0019682) |
0.2 | 0.5 | GO:0034395 | response to iron ion(GO:0010039) regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395) cellular response to iron ion(GO:0071281) |
0.2 | 1.0 | GO:0015802 | basic amino acid transport(GO:0015802) |
0.2 | 1.9 | GO:0071265 | L-methionine biosynthetic process(GO:0071265) |
0.2 | 0.8 | GO:0003400 | regulation of COPII vesicle coating(GO:0003400) regulation of vesicle targeting, to, from or within Golgi(GO:0048209) regulation of ER to Golgi vesicle-mediated transport by GTP hydrolysis(GO:0090113) |
0.2 | 1.3 | GO:0006865 | amino acid transport(GO:0006865) |
0.2 | 0.8 | GO:0043666 | regulation of phosphoprotein phosphatase activity(GO:0043666) |
0.2 | 0.5 | GO:0042710 | biofilm formation(GO:0042710) negative regulation of invasive growth in response to glucose limitation by negative regulation of transcription from RNA polymerase II promoter(GO:1900460) |
0.2 | 0.9 | GO:0006279 | premeiotic DNA replication(GO:0006279) |
0.1 | 0.3 | GO:0006103 | 2-oxoglutarate metabolic process(GO:0006103) |
0.1 | 0.6 | GO:0043112 | receptor recycling(GO:0001881) protein import into peroxisome matrix, receptor recycling(GO:0016562) receptor metabolic process(GO:0043112) |
0.1 | 0.6 | GO:0034227 | tRNA thio-modification(GO:0034227) |
0.1 | 1.0 | GO:0051322 | anaphase(GO:0051322) |
0.1 | 1.8 | GO:0046854 | lipid phosphorylation(GO:0046834) phosphatidylinositol phosphorylation(GO:0046854) |
0.1 | 0.7 | GO:0007534 | gene conversion at mating-type locus(GO:0007534) |
0.1 | 1.0 | GO:0051177 | meiotic sister chromatid cohesion(GO:0051177) |
0.1 | 0.3 | GO:0005985 | sucrose metabolic process(GO:0005985) sucrose catabolic process(GO:0005987) |
0.1 | 2.1 | GO:0007118 | budding cell apical bud growth(GO:0007118) |
0.1 | 0.6 | GO:0006627 | protein processing involved in protein targeting to mitochondrion(GO:0006627) |
0.1 | 1.1 | GO:0035023 | regulation of Rho protein signal transduction(GO:0035023) |
0.1 | 1.1 | GO:0040001 | establishment of mitotic spindle orientation(GO:0000132) establishment of mitotic spindle localization(GO:0040001) establishment of spindle orientation(GO:0051294) |
0.1 | 0.6 | GO:0071804 | cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805) |
0.1 | 0.6 | GO:0045144 | meiosis II(GO:0007135) meiotic sister chromatid segregation(GO:0045144) |
0.1 | 0.9 | GO:0000321 | re-entry into mitotic cell cycle after pheromone arrest(GO:0000321) |
0.1 | 0.4 | GO:0000078 | obsolete cytokinesis after mitosis checkpoint(GO:0000078) |
0.1 | 0.9 | GO:0000491 | small nucleolar ribonucleoprotein complex assembly(GO:0000491) |
0.1 | 0.2 | GO:0016578 | histone deubiquitination(GO:0016578) |
0.1 | 0.5 | GO:0071406 | response to methylmercury(GO:0051597) cellular response to methylmercury(GO:0071406) |
0.1 | 0.3 | GO:0006824 | cobalt ion transport(GO:0006824) |
0.1 | 0.5 | GO:0051569 | positive regulation of histone methylation(GO:0031062) regulation of histone H3-K4 methylation(GO:0051569) |
0.1 | 0.8 | GO:0031146 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146) |
0.1 | 0.4 | GO:0007234 | osmosensory signaling via phosphorelay pathway(GO:0007234) |
0.1 | 1.2 | GO:0051568 | histone H3-K4 methylation(GO:0051568) |
0.1 | 1.3 | GO:0031321 | ascospore-type prospore assembly(GO:0031321) |
0.1 | 0.3 | GO:0006089 | lactate metabolic process(GO:0006089) |
0.1 | 0.7 | GO:0006635 | fatty acid beta-oxidation(GO:0006635) |
0.1 | 1.8 | GO:0006298 | mismatch repair(GO:0006298) |
0.1 | 0.6 | GO:0070873 | regulation of glycogen biosynthetic process(GO:0005979) regulation of glycogen metabolic process(GO:0070873) |
0.1 | 0.4 | GO:0016036 | cellular response to phosphate starvation(GO:0016036) |
0.1 | 1.9 | GO:0000727 | double-strand break repair via break-induced replication(GO:0000727) |
0.1 | 0.3 | GO:0072530 | cytosine transport(GO:0015856) purine-containing compound transmembrane transport(GO:0072530) |
0.1 | 0.3 | GO:0031297 | replication fork processing(GO:0031297) |
0.1 | 0.4 | GO:0030042 | actin filament depolymerization(GO:0030042) |
0.1 | 0.1 | GO:1900544 | positive regulation of nucleotide metabolic process(GO:0045981) positive regulation of purine nucleotide metabolic process(GO:1900544) |
0.1 | 0.6 | GO:0006829 | zinc II ion transport(GO:0006829) |
0.1 | 1.1 | GO:0000422 | mitophagy(GO:0000422) mitochondrion disassembly(GO:0061726) |
0.1 | 1.1 | GO:0033617 | mitochondrial respiratory chain complex IV assembly(GO:0033617) |
0.1 | 0.7 | GO:0070987 | error-free translesion synthesis(GO:0070987) |
0.1 | 0.6 | GO:0018345 | protein palmitoylation(GO:0018345) |
0.1 | 0.5 | GO:0000266 | mitochondrial fission(GO:0000266) |
0.1 | 0.6 | GO:0034063 | stress granule assembly(GO:0034063) |
0.1 | 0.3 | GO:0006835 | dicarboxylic acid transport(GO:0006835) |
0.1 | 0.3 | GO:0001927 | exocyst assembly(GO:0001927) |
0.1 | 1.3 | GO:0006312 | mitotic recombination(GO:0006312) |
0.1 | 0.6 | GO:0000755 | cytogamy(GO:0000755) |
0.1 | 0.9 | GO:0043486 | histone exchange(GO:0043486) |
0.1 | 0.6 | GO:0034085 | establishment of sister chromatid cohesion(GO:0034085) establishment of mitotic sister chromatid cohesion(GO:0034087) |
0.1 | 0.3 | GO:0046688 | response to copper ion(GO:0046688) |
0.1 | 0.9 | GO:0006513 | protein monoubiquitination(GO:0006513) |
0.1 | 1.0 | GO:0006515 | misfolded or incompletely synthesized protein catabolic process(GO:0006515) |
0.1 | 0.3 | GO:0000715 | nucleotide-excision repair, DNA damage recognition(GO:0000715) |
0.1 | 0.4 | GO:0072348 | sulfur compound transport(GO:0072348) |
0.1 | 0.7 | GO:0016925 | protein sumoylation(GO:0016925) |
0.1 | 0.2 | GO:0072396 | cellular response to biotic stimulus(GO:0071216) response to cell cycle checkpoint signaling(GO:0072396) response to mitotic cell cycle checkpoint signaling(GO:0072414) response to spindle checkpoint signaling(GO:0072417) response to mitotic spindle checkpoint signaling(GO:0072476) response to mitotic cell cycle spindle assembly checkpoint signaling(GO:0072479) response to spindle assembly checkpoint signaling(GO:0072485) negative regulation of protein import into nucleus during spindle assembly checkpoint(GO:1901925) |
0.1 | 2.5 | GO:0006631 | fatty acid metabolic process(GO:0006631) |
0.1 | 0.2 | GO:0060237 | regulation of fungal-type cell wall organization(GO:0060237) |
0.1 | 0.7 | GO:0016579 | protein deubiquitination(GO:0016579) |
0.0 | 0.6 | GO:0044396 | actin cortical patch assembly(GO:0000147) actin cortical patch organization(GO:0044396) |
0.0 | 0.3 | GO:0010388 | protein deneddylation(GO:0000338) cullin deneddylation(GO:0010388) |
0.0 | 0.4 | GO:0005978 | glycogen biosynthetic process(GO:0005978) |
0.0 | 0.7 | GO:0006081 | cellular aldehyde metabolic process(GO:0006081) |
0.0 | 0.1 | GO:0034503 | protein localization to nucleolar rDNA repeats(GO:0034503) |
0.0 | 0.1 | GO:0016577 | protein demethylation(GO:0006482) protein dealkylation(GO:0008214) histone demethylation(GO:0016577) demethylation(GO:0070988) |
0.0 | 0.6 | GO:0001300 | chronological cell aging(GO:0001300) |
0.0 | 0.2 | GO:0051053 | negative regulation of DNA metabolic process(GO:0051053) |
0.0 | 0.1 | GO:0005980 | glycogen catabolic process(GO:0005980) |
0.0 | 0.6 | GO:0008361 | regulation of cell size(GO:0008361) |
0.0 | 0.6 | GO:0001558 | regulation of cell growth(GO:0001558) |
0.0 | 0.2 | GO:0070124 | mitochondrial translational initiation(GO:0070124) |
0.0 | 0.1 | GO:0000114 | obsolete regulation of transcription involved in G1 phase of mitotic cell cycle(GO:0000114) |
0.0 | 0.2 | GO:0006452 | translational frameshifting(GO:0006452) |
0.0 | 0.2 | GO:0000103 | sulfate assimilation(GO:0000103) |
0.0 | 0.3 | GO:0006656 | phosphatidylcholine biosynthetic process(GO:0006656) |
0.0 | 0.1 | GO:0048279 | vesicle fusion with endoplasmic reticulum(GO:0048279) |
0.0 | 0.2 | GO:0006491 | N-glycan processing(GO:0006491) |
0.0 | 0.2 | GO:0000350 | generation of catalytic spliceosome for second transesterification step(GO:0000350) |
0.0 | 0.2 | GO:0070816 | phosphorylation of RNA polymerase II C-terminal domain(GO:0070816) |
0.0 | 0.0 | GO:0032509 | endosome transport via multivesicular body sorting pathway(GO:0032509) |
0.0 | 0.1 | GO:0032205 | negative regulation of telomere maintenance(GO:0032205) negative regulation of homeostatic process(GO:0032845) |
0.0 | 0.1 | GO:0070676 | intralumenal vesicle formation(GO:0070676) |
0.0 | 1.4 | GO:0006310 | DNA recombination(GO:0006310) |
0.0 | 0.1 | GO:0051098 | regulation of binding(GO:0051098) |
0.0 | 0.2 | GO:0031167 | rRNA methylation(GO:0031167) |
0.0 | 0.2 | GO:0045005 | DNA-dependent DNA replication maintenance of fidelity(GO:0045005) |
0.0 | 0.3 | GO:0032005 | pheromone-dependent signal transduction involved in conjugation with cellular fusion(GO:0000750) signal transduction involved in conjugation with cellular fusion(GO:0032005) |
0.0 | 0.2 | GO:0070127 | tRNA aminoacylation for mitochondrial protein translation(GO:0070127) |
0.0 | 0.2 | GO:0015749 | hexose transport(GO:0008645) monosaccharide transport(GO:0015749) |
0.0 | 0.0 | GO:0018206 | N-terminal peptidyl-methionine acetylation(GO:0017196) peptidyl-methionine modification(GO:0018206) |
0.0 | 0.0 | GO:0046461 | triglyceride catabolic process(GO:0019433) neutral lipid catabolic process(GO:0046461) acylglycerol catabolic process(GO:0046464) |
0.0 | 0.1 | GO:0043461 | mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615) proton-transporting ATP synthase complex assembly(GO:0043461) |
0.0 | 0.2 | GO:0000002 | mitochondrial genome maintenance(GO:0000002) |
0.0 | 0.0 | GO:0007019 | microtubule depolymerization(GO:0007019) |
0.0 | 0.1 | GO:0097034 | mitochondrial respiratory chain complex IV biogenesis(GO:0097034) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.1 | 4.3 | GO:0097042 | extrinsic component of fungal-type vacuolar membrane(GO:0097042) |
0.8 | 7.4 | GO:0000276 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263) |
0.8 | 2.4 | GO:0032807 | DNA ligase IV complex(GO:0032807) |
0.7 | 4.2 | GO:0033263 | CORVET complex(GO:0033263) |
0.7 | 2.1 | GO:1990316 | ATG1/ULK1 kinase complex(GO:1990316) |
0.6 | 8.4 | GO:0005619 | ascospore wall(GO:0005619) |
0.6 | 1.9 | GO:0032585 | multivesicular body membrane(GO:0032585) |
0.6 | 2.3 | GO:0032116 | SMC loading complex(GO:0032116) |
0.5 | 3.4 | GO:0000112 | nucleotide-excision repair factor 3 complex(GO:0000112) |
0.5 | 1.4 | GO:0005756 | mitochondrial proton-transporting ATP synthase, central stalk(GO:0005756) proton-transporting ATP synthase, central stalk(GO:0045269) |
0.5 | 2.3 | GO:0032221 | Rpd3S complex(GO:0032221) |
0.4 | 22.2 | GO:0031225 | anchored component of membrane(GO:0031225) |
0.4 | 1.9 | GO:0045273 | mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283) |
0.4 | 0.8 | GO:0030061 | mitochondrial crista(GO:0030061) |
0.4 | 1.5 | GO:0034271 | phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) |
0.3 | 2.9 | GO:0005770 | late endosome(GO:0005770) |
0.3 | 0.9 | GO:0031422 | RecQ helicase-Topo III complex(GO:0031422) |
0.3 | 2.7 | GO:0005750 | mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275) |
0.3 | 1.2 | GO:0005825 | half bridge of spindle pole body(GO:0005825) |
0.3 | 2.1 | GO:0034657 | GID complex(GO:0034657) |
0.3 | 4.4 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
0.3 | 0.5 | GO:0045261 | mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261) |
0.3 | 0.8 | GO:0005947 | mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) mitochondrial oxoglutarate dehydrogenase complex(GO:0009353) dihydrolipoyl dehydrogenase complex(GO:0045240) oxoglutarate dehydrogenase complex(GO:0045252) |
0.3 | 2.3 | GO:0000795 | synaptonemal complex(GO:0000795) |
0.3 | 1.3 | GO:0072379 | ER membrane insertion complex(GO:0072379) TRC complex(GO:0072380) |
0.2 | 0.7 | GO:0042720 | mitochondrial inner membrane peptidase complex(GO:0042720) |
0.2 | 0.9 | GO:0031901 | early endosome membrane(GO:0031901) |
0.2 | 0.8 | GO:0001400 | mating projection base(GO:0001400) |
0.2 | 0.8 | GO:0033551 | monopolin complex(GO:0033551) |
0.2 | 0.6 | GO:0032177 | split septin rings(GO:0032176) cellular bud neck split septin rings(GO:0032177) |
0.2 | 1.2 | GO:0005664 | origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664) |
0.2 | 0.4 | GO:0000306 | extrinsic component of vacuolar membrane(GO:0000306) |
0.2 | 4.2 | GO:0005628 | prospore membrane(GO:0005628) intracellular immature spore(GO:0042763) ascospore-type prospore(GO:0042764) |
0.2 | 0.7 | GO:0000148 | 1,3-beta-D-glucan synthase complex(GO:0000148) |
0.2 | 0.6 | GO:0033100 | NuA3 histone acetyltransferase complex(GO:0033100) H3 histone acetyltransferase complex(GO:0070775) |
0.2 | 1.1 | GO:0034967 | Set3 complex(GO:0034967) |
0.2 | 2.0 | GO:0070469 | respiratory chain(GO:0070469) |
0.1 | 0.3 | GO:0005674 | transcription factor TFIIF complex(GO:0005674) |
0.1 | 0.3 | GO:0032389 | MutLalpha complex(GO:0032389) |
0.1 | 0.7 | GO:0035361 | Cul8-RING ubiquitin ligase complex(GO:0035361) |
0.1 | 0.9 | GO:0019897 | extrinsic component of plasma membrane(GO:0019897) |
0.1 | 2.1 | GO:0031306 | intrinsic component of mitochondrial outer membrane(GO:0031306) integral component of mitochondrial outer membrane(GO:0031307) |
0.1 | 1.0 | GO:0000235 | astral microtubule(GO:0000235) aster(GO:0005818) |
0.1 | 1.3 | GO:0005782 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
0.1 | 0.6 | GO:0038201 | TOR complex(GO:0038201) |
0.1 | 6.9 | GO:0044440 | endosome membrane(GO:0010008) endosomal part(GO:0044440) |
0.1 | 1.1 | GO:0098552 | side of membrane(GO:0098552) cytoplasmic side of membrane(GO:0098562) |
0.1 | 0.3 | GO:0000110 | nucleotide-excision repair factor 1 complex(GO:0000110) |
0.1 | 0.9 | GO:0005656 | nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387) |
0.1 | 0.4 | GO:0032865 | ERMES complex(GO:0032865) ER-mitochondrion membrane contact site(GO:0044233) |
0.1 | 0.4 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
0.1 | 1.0 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
0.1 | 0.9 | GO:0005686 | U2 snRNP(GO:0005686) |
0.1 | 12.0 | GO:0005743 | mitochondrial inner membrane(GO:0005743) |
0.1 | 1.7 | GO:0016592 | mediator complex(GO:0016592) |
0.1 | 0.3 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
0.1 | 3.1 | GO:0042579 | peroxisome(GO:0005777) microbody(GO:0042579) |
0.1 | 2.6 | GO:0030479 | actin cortical patch(GO:0030479) endocytic patch(GO:0061645) |
0.1 | 0.1 | GO:0000126 | transcription factor TFIIIB complex(GO:0000126) |
0.1 | 0.2 | GO:0071819 | DUBm complex(GO:0071819) |
0.1 | 0.2 | GO:0035649 | Nrd1 complex(GO:0035649) |
0.1 | 2.4 | GO:0005934 | cellular bud tip(GO:0005934) |
0.1 | 2.8 | GO:0000131 | incipient cellular bud site(GO:0000131) |
0.0 | 0.3 | GO:0008180 | COP9 signalosome(GO:0008180) |
0.0 | 0.2 | GO:0000799 | condensin complex(GO:0000796) nuclear condensin complex(GO:0000799) |
0.0 | 0.7 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
0.0 | 0.3 | GO:0032777 | Piccolo NuA4 histone acetyltransferase complex(GO:0032777) |
0.0 | 0.4 | GO:0090544 | SWI/SNF complex(GO:0016514) BAF-type complex(GO:0090544) |
0.0 | 0.6 | GO:0005682 | U5 snRNP(GO:0005682) |
0.0 | 0.2 | GO:0000506 | glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506) |
0.0 | 0.3 | GO:0071007 | U2-type catalytic step 2 spliceosome(GO:0071007) catalytic step 2 spliceosome(GO:0071013) |
0.0 | 0.9 | GO:0000932 | cytoplasmic mRNA processing body(GO:0000932) |
0.0 | 0.1 | GO:0005871 | kinesin complex(GO:0005871) |
0.0 | 0.3 | GO:0097526 | U4/U6 x U5 tri-snRNP complex(GO:0046540) spliceosomal tri-snRNP complex(GO:0097526) |
0.0 | 1.3 | GO:0005643 | nuclear pore(GO:0005643) |
0.0 | 0.5 | GO:0097346 | INO80-type complex(GO:0097346) |
0.0 | 0.8 | GO:0090575 | RNA polymerase II transcription factor complex(GO:0090575) |
0.0 | 0.0 | GO:0070209 | ASTRA complex(GO:0070209) |
0.0 | 0.1 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
0.0 | 0.1 | GO:0000500 | RNA polymerase I upstream activating factor complex(GO:0000500) |
0.0 | 0.1 | GO:0033588 | Elongator holoenzyme complex(GO:0033588) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.8 | 11.2 | GO:0005537 | mannose binding(GO:0005537) |
2.4 | 9.7 | GO:0016661 | oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661) |
1.9 | 7.5 | GO:0015603 | siderophore transmembrane transporter activity(GO:0015343) iron chelate transmembrane transporter activity(GO:0015603) siderophore transporter activity(GO:0042927) |
1.5 | 1.5 | GO:0042947 | alpha-glucoside transmembrane transporter activity(GO:0015151) glucoside transmembrane transporter activity(GO:0042947) |
1.3 | 5.3 | GO:0004032 | alditol:NADP+ 1-oxidoreductase activity(GO:0004032) |
1.0 | 15.3 | GO:0015293 | symporter activity(GO:0015293) |
0.9 | 2.8 | GO:0004088 | carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088) |
0.9 | 3.6 | GO:0016639 | oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639) |
0.9 | 9.4 | GO:0046933 | proton-transporting ATP synthase activity, rotational mechanism(GO:0046933) |
0.8 | 3.4 | GO:0045118 | azole transporter activity(GO:0045118) |
0.8 | 4.1 | GO:0018456 | aryl-alcohol dehydrogenase (NAD+) activity(GO:0018456) |
0.8 | 4.6 | GO:0016888 | endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888) |
0.7 | 2.2 | GO:0016813 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813) |
0.7 | 2.1 | GO:0016208 | AMP binding(GO:0016208) acid-ammonia (or amide) ligase activity(GO:0016880) |
0.7 | 5.4 | GO:0015205 | nucleobase transmembrane transporter activity(GO:0015205) |
0.7 | 2.0 | GO:0003840 | gamma-glutamyltransferase activity(GO:0003840) |
0.7 | 3.3 | GO:0016783 | sulfurtransferase activity(GO:0016783) |
0.7 | 12.6 | GO:0015297 | antiporter activity(GO:0015297) |
0.6 | 4.3 | GO:0004364 | glutathione transferase activity(GO:0004364) |
0.6 | 2.4 | GO:0004430 | 1-phosphatidylinositol 4-kinase activity(GO:0004430) |
0.6 | 2.4 | GO:0000772 | mating pheromone activity(GO:0000772) pheromone activity(GO:0005186) |
0.6 | 1.8 | GO:0004861 | cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861) |
0.6 | 0.6 | GO:0016597 | amino acid binding(GO:0016597) |
0.5 | 3.3 | GO:0016721 | superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721) |
0.5 | 1.1 | GO:0001097 | RNA polymerase II basal transcription factor binding(GO:0001091) TFIIH-class transcription factor binding(GO:0001097) |
0.5 | 1.6 | GO:0003873 | 6-phosphofructo-2-kinase activity(GO:0003873) |
0.5 | 1.5 | GO:0016872 | intramolecular lyase activity(GO:0016872) |
0.5 | 3.0 | GO:0016846 | carbon-sulfur lyase activity(GO:0016846) |
0.5 | 1.4 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
0.5 | 0.5 | GO:0015101 | organic cation transmembrane transporter activity(GO:0015101) |
0.5 | 2.7 | GO:0016653 | oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor(GO:0016653) |
0.4 | 2.7 | GO:0004030 | aldehyde dehydrogenase (NAD) activity(GO:0004029) aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030) |
0.4 | 3.0 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
0.4 | 4.1 | GO:0043495 | protein anchor(GO:0043495) |
0.4 | 2.4 | GO:0000014 | single-stranded DNA endodeoxyribonuclease activity(GO:0000014) |
0.4 | 1.9 | GO:0008177 | succinate dehydrogenase (ubiquinone) activity(GO:0008177) |
0.4 | 1.9 | GO:0017022 | myosin binding(GO:0017022) |
0.4 | 1.5 | GO:0008195 | phosphatidate phosphatase activity(GO:0008195) |
0.4 | 1.9 | GO:0004806 | triglyceride lipase activity(GO:0004806) retinyl-palmitate esterase activity(GO:0050253) |
0.4 | 2.2 | GO:0016744 | transferase activity, transferring aldehyde or ketonic groups(GO:0016744) |
0.4 | 12.4 | GO:0015171 | amino acid transmembrane transporter activity(GO:0015171) |
0.3 | 1.7 | GO:0004075 | biotin carboxylase activity(GO:0004075) |
0.3 | 4.0 | GO:0022838 | substrate-specific channel activity(GO:0022838) |
0.3 | 0.6 | GO:0001227 | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227) |
0.3 | 3.5 | GO:0035251 | UDP-glucosyltransferase activity(GO:0035251) |
0.3 | 0.8 | GO:0050833 | pyruvate transmembrane transporter activity(GO:0050833) |
0.2 | 2.6 | GO:0030983 | mismatched DNA binding(GO:0030983) |
0.2 | 0.9 | GO:0003916 | DNA topoisomerase activity(GO:0003916) |
0.2 | 0.7 | GO:0004866 | endopeptidase inhibitor activity(GO:0004866) peptidase inhibitor activity(GO:0030414) |
0.2 | 2.7 | GO:0001190 | transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811) |
0.2 | 4.4 | GO:0016209 | antioxidant activity(GO:0016209) |
0.2 | 0.6 | GO:0004930 | G-protein coupled receptor activity(GO:0004930) |
0.2 | 0.6 | GO:0050308 | sugar-phosphatase activity(GO:0050308) |
0.2 | 0.6 | GO:0070569 | uridylyltransferase activity(GO:0070569) |
0.2 | 0.9 | GO:0016638 | oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638) |
0.2 | 0.9 | GO:0097372 | NAD-dependent histone deacetylase activity (H3-K18 specific)(GO:0097372) |
0.2 | 1.1 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
0.2 | 0.9 | GO:0008198 | ferrous iron binding(GO:0008198) |
0.2 | 0.2 | GO:0016878 | CoA-ligase activity(GO:0016405) acid-thiol ligase activity(GO:0016878) |
0.2 | 2.2 | GO:0031625 | ubiquitin protein ligase binding(GO:0031625) ubiquitin-like protein ligase binding(GO:0044389) |
0.2 | 0.3 | GO:0001094 | TFIID-class transcription factor binding(GO:0001094) |
0.2 | 1.6 | GO:0016628 | oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628) |
0.1 | 9.9 | GO:0000982 | transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) |
0.1 | 4.3 | GO:0008234 | cysteine-type peptidase activity(GO:0008234) |
0.1 | 0.7 | GO:0019789 | SUMO transferase activity(GO:0019789) |
0.1 | 0.4 | GO:0019212 | protein phosphatase inhibitor activity(GO:0004864) phosphatase inhibitor activity(GO:0019212) |
0.1 | 1.7 | GO:0005199 | structural constituent of cell wall(GO:0005199) |
0.1 | 1.5 | GO:0046912 | transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912) |
0.1 | 3.4 | GO:0061733 | histone acetyltransferase activity(GO:0004402) peptide-lysine-N-acetyltransferase activity(GO:0061733) |
0.1 | 0.5 | GO:0008353 | RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353) |
0.1 | 0.4 | GO:0008409 | 5'-3' exonuclease activity(GO:0008409) |
0.1 | 0.5 | GO:0005315 | inorganic phosphate transmembrane transporter activity(GO:0005315) |
0.1 | 0.5 | GO:0017057 | 6-phosphogluconolactonase activity(GO:0017057) |
0.1 | 0.6 | GO:0043142 | single-stranded DNA-dependent ATPase activity(GO:0043142) |
0.1 | 0.5 | GO:0004535 | poly(A)-specific ribonuclease activity(GO:0004535) |
0.1 | 0.9 | GO:0016675 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
0.1 | 3.5 | GO:0001076 | transcription factor activity, RNA polymerase II transcription factor binding(GO:0001076) |
0.1 | 1.2 | GO:0016413 | O-acetyltransferase activity(GO:0016413) |
0.1 | 0.4 | GO:0000156 | phosphorelay response regulator activity(GO:0000156) |
0.1 | 0.3 | GO:0016417 | S-acyltransferase activity(GO:0016417) |
0.1 | 0.3 | GO:0072542 | protein phosphatase activator activity(GO:0072542) |
0.1 | 1.2 | GO:0004702 | receptor signaling protein serine/threonine kinase activity(GO:0004702) |
0.1 | 0.1 | GO:0051864 | histone demethylase activity (H3-K36 specific)(GO:0051864) |
0.1 | 0.7 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
0.1 | 1.3 | GO:0008236 | serine-type peptidase activity(GO:0008236) |
0.1 | 0.3 | GO:0004458 | D-lactate dehydrogenase (cytochrome) activity(GO:0004458) |
0.1 | 0.7 | GO:0016833 | oxo-acid-lyase activity(GO:0016833) |
0.1 | 0.6 | GO:0008028 | monocarboxylic acid transmembrane transporter activity(GO:0008028) |
0.1 | 1.4 | GO:0003746 | translation elongation factor activity(GO:0003746) |
0.1 | 1.0 | GO:0042803 | protein homodimerization activity(GO:0042803) |
0.1 | 0.9 | GO:0015036 | protein disulfide oxidoreductase activity(GO:0015035) disulfide oxidoreductase activity(GO:0015036) |
0.1 | 0.3 | GO:0005310 | dicarboxylic acid transmembrane transporter activity(GO:0005310) |
0.1 | 1.3 | GO:0000990 | transcription factor activity, core RNA polymerase binding(GO:0000990) |
0.1 | 7.7 | GO:0004674 | protein serine/threonine kinase activity(GO:0004674) |
0.1 | 0.6 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
0.1 | 0.4 | GO:1901682 | sulfur compound transmembrane transporter activity(GO:1901682) |
0.1 | 0.7 | GO:0003777 | microtubule motor activity(GO:0003777) |
0.1 | 0.1 | GO:0015085 | calcium ion transmembrane transporter activity(GO:0015085) |
0.1 | 1.0 | GO:0016831 | carboxy-lyase activity(GO:0016831) |
0.1 | 0.4 | GO:0047429 | nucleoside-triphosphate diphosphatase activity(GO:0047429) |
0.1 | 1.2 | GO:0019901 | protein kinase binding(GO:0019901) |
0.1 | 3.4 | GO:0000981 | RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981) |
0.1 | 0.4 | GO:0031369 | translation initiation factor binding(GO:0031369) |
0.0 | 0.5 | GO:0008599 | protein phosphatase type 1 regulator activity(GO:0008599) |
0.0 | 0.1 | GO:0004450 | isocitrate dehydrogenase (NADP+) activity(GO:0004450) |
0.0 | 0.0 | GO:0017171 | serine hydrolase activity(GO:0017171) |
0.0 | 0.1 | GO:0033549 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) MAP kinase phosphatase activity(GO:0033549) |
0.0 | 0.4 | GO:0000293 | ferric-chelate reductase activity(GO:0000293) oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor(GO:0016723) |
0.0 | 0.2 | GO:0000033 | alpha-1,3-mannosyltransferase activity(GO:0000033) |
0.0 | 0.2 | GO:0017176 | phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176) |
0.0 | 0.7 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
0.0 | 3.1 | GO:0004842 | ubiquitin-protein transferase activity(GO:0004842) |
0.0 | 0.5 | GO:0009055 | electron carrier activity(GO:0009055) |
0.0 | 0.8 | GO:0003688 | DNA replication origin binding(GO:0003688) |
0.0 | 1.1 | GO:0003697 | single-stranded DNA binding(GO:0003697) |
0.0 | 0.2 | GO:0008171 | O-methyltransferase activity(GO:0008171) |
0.0 | 0.1 | GO:0034596 | phosphatidylinositol phosphate 4-phosphatase activity(GO:0034596) phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812) |
0.0 | 0.4 | GO:0045182 | translation regulator activity(GO:0045182) |
0.0 | 0.2 | GO:0001003 | RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003) transcription factor activity, RNA polymerase III promoter sequence-specific binding, TFIIIB recruiting(GO:0001004) transcription factor activity, RNA polymerase III type 1 promoter sequence-specific binding, TFIIIB recruiting(GO:0001005) transcription factor activity, RNA polymerase III type 2 promoter sequence-specific binding, TFIIIB recruiting(GO:0001008) RNA polymerase III type 2 promoter DNA binding(GO:0001031) RNA polymerase III transcription factor activity, sequence-specific DNA binding(GO:0001034) |
0.0 | 0.2 | GO:0017048 | Rho GTPase binding(GO:0017048) |
0.0 | 0.1 | GO:0001099 | RNA polymerase II core binding(GO:0000993) basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099) |
0.0 | 0.6 | GO:0005509 | calcium ion binding(GO:0005509) |
0.0 | 0.3 | GO:0005088 | Ras guanyl-nucleotide exchange factor activity(GO:0005088) |
0.0 | 0.3 | GO:0003713 | transcription coactivator activity(GO:0003713) |
0.0 | 0.1 | GO:0070403 | NAD+ binding(GO:0070403) |
0.0 | 0.2 | GO:0031072 | heat shock protein binding(GO:0031072) |
0.0 | 0.3 | GO:0003684 | damaged DNA binding(GO:0003684) |
0.0 | 0.3 | GO:0004725 | protein tyrosine phosphatase activity(GO:0004725) |
0.0 | 0.5 | GO:0005484 | SNAP receptor activity(GO:0005484) |
0.0 | 0.2 | GO:0000386 | second spliceosomal transesterification activity(GO:0000386) |
0.0 | 0.2 | GO:0019904 | protein domain specific binding(GO:0019904) |
0.0 | 0.1 | GO:0015450 | P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450) |
0.0 | 0.2 | GO:0019888 | protein phosphatase regulator activity(GO:0019888) |
0.0 | 0.2 | GO:0003774 | motor activity(GO:0003774) |
0.0 | 0.1 | GO:0001163 | RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) transcription factor activity, RNA polymerase I upstream control element sequence-specific binding(GO:0001168) |
0.0 | 0.2 | GO:0004659 | prenyltransferase activity(GO:0004659) |
0.0 | 0.1 | GO:0000149 | SNARE binding(GO:0000149) |
0.0 | 0.1 | GO:0004407 | histone deacetylase activity(GO:0004407) protein deacetylase activity(GO:0033558) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.5 | 4.5 | PID FOXO PATHWAY | FoxO family signaling |
0.6 | 1.9 | PID EPHA2 FWD PATHWAY | EPHA2 forward signaling |
0.4 | 1.6 | PID CXCR4 PATHWAY | CXCR4-mediated signaling events |
0.4 | 0.4 | PID ANGIOPOIETIN RECEPTOR PATHWAY | Angiopoietin receptor Tie2-mediated signaling |
0.4 | 0.7 | PID RB 1PATHWAY | Regulation of retinoblastoma protein |
0.3 | 0.6 | PID IL4 2PATHWAY | IL4-mediated signaling events |
0.2 | 0.5 | PID ERBB2 ERBB3 PATHWAY | ErbB2/ErbB3 signaling events |
0.1 | 0.4 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
0.1 | 0.4 | PID CMYB PATHWAY | C-MYB transcription factor network |
0.1 | 124.7 | PID P38 MKK3 6PATHWAY | p38 MAPK signaling pathway |
0.1 | 0.2 | SA G1 AND S PHASES | Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition. |
0.1 | 0.4 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 1.3 | REACTOME SHC1 EVENTS IN ERBB4 SIGNALING | Genes involved in SHC1 events in ERBB4 signaling |
0.3 | 2.4 | REACTOME MEIOTIC RECOMBINATION | Genes involved in Meiotic Recombination |
0.3 | 2.5 | REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES | Genes involved in Metabolism of amino acids and derivatives |
0.2 | 1.2 | REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION | Genes involved in E2F-enabled inhibition of pre-replication complex formation |
0.2 | 0.5 | REACTOME NETRIN1 SIGNALING | Genes involved in Netrin-1 signaling |
0.1 | 0.4 | REACTOME MEIOTIC SYNAPSIS | Genes involved in Meiotic Synapsis |
0.1 | 0.3 | REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION | Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression |
0.1 | 124.7 | REACTOME CHONDROITIN SULFATE BIOSYNTHESIS | Genes involved in Chondroitin sulfate biosynthesis |
0.1 | 0.7 | REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING | Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening |
0.1 | 0.6 | REACTOME GLUCONEOGENESIS | Genes involved in Gluconeogenesis |
0.0 | 0.3 | REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN | Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein |
0.0 | 0.1 | REACTOME TRANSCRIPTION | Genes involved in Transcription |
0.0 | 0.2 | REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |