Gene Symbol | Gene ID | Gene Info |
---|---|---|
ACE2
|
S000004121 | Transcription factor required for septum destruction after cytokinesis |
Promoter | Log-likelihood | Transcript | Gene | Gene Info |
---|---|---|---|---|
YLR154W-B | 35.30 |
Dubious open reading frame unlikely to encode a protein; encoded within the the 25S rRNA gene on the opposite strand |
||
YLR154W-A | 34.61 |
Dubious open reading frame unlikely to encode a protein; encoded within the the 25S rRNA gene on the opposite strand |
||
YLR154C | 33.29 |
RNH203
|
Ribonuclease H2 subunit, required for RNase H2 activity |
|
YER124C | 32.89 |
DSE1
|
Daughter cell-specific protein, may participate in pathways regulating cell wall metabolism; deletion affects cell separation after division and sensitivity to drugs targeted against the cell wall |
|
YFR055W | 32.75 |
IRC7
|
Putative cystathionine beta-lyase; involved in copper ion homeostasis and sulfur metabolism; null mutant displays increased levels of spontaneous Rad52p foci; expression induced by nitrogen limitation in a GLN3, GAT1-dependent manner |
|
YDL055C | 30.16 |
PSA1
|
GDP-mannose pyrophosphorylase (mannose-1-phosphate guanyltransferase), synthesizes GDP-mannose from GTP and mannose-1-phosphate in cell wall biosynthesis; required for normal cell wall structure |
|
YFR056C | 26.89 |
Dubious open reading frame unlikely to encode a protein based on available experimental and comparative sequence data; partially overlaps the uncharacterized gene YFR055W |
||
YNL327W | 25.80 |
EGT2
|
Glycosylphosphatidylinositol (GPI)-anchored cell wall endoglucanase required for proper cell separation after cytokinesis, expression is activated by Swi5p and tightly regulated in a cell cycle-dependent manner |
|
YNL066W | 19.57 |
SUN4
|
Cell wall protein related to glucanases, possibly involved in cell wall septation; member of the SUN family |
|
YHR143W | 19.23 |
DSE2
|
Daughter cell-specific secreted protein with similarity to glucanases, degrades cell wall from the daughter side causing daughter to separate from mother; expression is repressed by cAMP |
|
YDR345C | 19.02 |
HXT3
|
Low affinity glucose transporter of the major facilitator superfamily, expression is induced in low or high glucose conditions |
|
YKR092C | 18.80 |
SRP40
|
Nucleolar, serine-rich protein with a role in preribosome assembly or transport; may function as a chaperone of small nucleolar ribonucleoprotein particles (snoRNPs); immunologically and structurally to rat Nopp140 |
|
YGL028C | 17.73 |
SCW11
|
Cell wall protein with similarity to glucanases; may play a role in conjugation during mating based on its regulation by Ste12p |
|
YLR286C | 17.29 |
CTS1
|
Endochitinase, required for cell separation after mitosis; transcriptional activation during late G and early M cell cycle phases is mediated by transcription factor Ace2p |
|
YJR094W-A | 16.04 |
RPL43B
|
Protein component of the large (60S) ribosomal subunit, identical to Rpl43Ap and has similarity to rat L37a ribosomal protein |
|
YLR154W-C | 15.58 |
TAR1
|
Mitochondrial protein of unknown function, overexpression suppresses an rpo41 mutation affecting mitochondrial RNA polymerase; encoded within the 25S rRNA gene on the opposite strand |
|
YOL086C | 14.63 |
ADH1
|
Alcohol dehydrogenase, fermentative isozyme active as homo- or heterotetramers; required for the reduction of acetaldehyde to ethanol, the last step in the glycolytic pathway |
|
YBR158W | 13.49 |
AMN1
|
Protein required for daughter cell separation, multiple mitotic checkpoints, and chromosome stability; contains 12 degenerate leucine-rich repeat motifs; expression is induced by the Mitotic Exit Network (MEN) |
|
YGL031C | 13.44 |
RPL24A
|
Ribosomal protein L30 of the large (60S) ribosomal subunit, nearly identical to Rpl24Bp and has similarity to rat L24 ribosomal protein; not essential for translation but may be required for normal translation rate |
|
YGL030W | 13.40 |
RPL30
|
Protein component of the large (60S) ribosomal subunit, has similarity to rat L30 ribosomal protein; involved in pre-rRNA processing in the nucleolus; autoregulates splicing of its transcript |
|
YKL164C | 12.51 |
PIR1
|
O-glycosylated protein required for cell wall stability; attached to the cell wall via beta-1,3-glucan; mediates mitochondrial translocation of Apn1p; expression regulated by the cell integrity pathway and by Swi5p during the cell cycle |
|
YNL178W | 12.33 |
RPS3
|
Protein component of the small (40S) ribosomal subunit, has apurinic/apyrimidinic (AP) endonuclease activity; essential for viability; has similarity to E. coli S3 and rat S3 ribosomal proteins |
|
YNR067C | 12.17 |
DSE4
|
Daughter cell-specific secreted protein with similarity to glucanases, degrades cell wall from the daughter side causing daughter to separate from mother |
|
YLR110C | 12.09 |
CCW12
|
Cell wall mannoprotein, mutants are defective in mating and agglutination, expression is downregulated by alpha-factor |
|
YOR263C | 12.04 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF DES3/YOR264W |
||
YJL136C | 11.46 |
RPS21B
|
Protein component of the small (40S) ribosomal subunit; nearly identical to Rps21Ap and has similarity to rat S21 ribosomal protein |
|
YGR108W | 10.67 |
CLB1
|
B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the transition from G2 to M phase; accumulates during G2 and M, then targeted via a destruction box motif for ubiquitin-mediated degradation by the proteasome |
|
YFL022C | 10.57 |
FRS2
|
Alpha subunit of cytoplasmic phenylalanyl-tRNA synthetase, forms a tetramer with Frs1p to form active enzyme; evolutionarily distant from mitochondrial phenylalanyl-tRNA synthetase based on protein sequence, but substrate binding is similar |
|
YKL218C | 10.55 |
SRY1
|
3-hydroxyaspartate dehydratase, deaminates L-threo-3-hydroxyaspartate to form oxaloacetate and ammonia; required for survival in the presence of hydroxyaspartate |
|
YDR385W | 10.54 |
EFT2
|
Elongation factor 2 (EF-2), also encoded by EFT1; catalyzes ribosomal translocation during protein synthesis; contains diphthamide, the unique posttranslationally modified histidine residue specifically ADP-ribosylated by diphtheria toxin |
|
YDR133C | 10.28 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps YDR134C |
||
YOR315W | 10.12 |
SFG1
|
Nuclear protein, putative transcription factor required for growth of superficial pseudohyphae (which do not invade the agar substrate) but not for invasive pseudohyphal growth; may act together with Phd1p; potential Cdc28p substrate |
|
YOR264W | 10.03 |
DSE3
|
Daughter cell-specific protein, may help establish daughter fate |
|
YER131W | 10.02 |
RPS26B
|
Protein component of the small (40S) ribosomal subunit; nearly identical to Rps26Ap and has similarity to rat S26 ribosomal protein |
|
YIR021W | 9.95 |
MRS1
|
Protein required for the splicing of two mitochondrial group I introns (BI3 in COB and AI5beta in COX1); forms a splicing complex, containing four subunits of Mrs1p and two subunits of the BI3-encoded maturase, that binds to the BI3 RNA |
|
YKL063C | 9.53 |
Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the Golgi |
||
YOR342C | 9.36 |
Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and the nucleus |
||
YOR176W | 8.94 |
HEM15
|
Ferrochelatase, a mitochondrial inner membrane protein, catalyzes the insertion of ferrous iron into protoporphyrin IX, the eighth and final step in the heme biosynthetic pathway |
|
YCR018C | 8.66 |
SRD1
|
Protein involved in the processing of pre-rRNA to mature rRNA; contains a C2/C2 zinc finger motif; srd1 mutation suppresses defects caused by the rrp1-1 mutation |
|
YIL118W | 8.38 |
RHO3
|
Non-essential small GTPase of the Rho/Rac subfamily of Ras-like proteins involved in the establishment of cell polarity; GTPase activity positively regulated by the GTPase activating protein (GAP) Rgd1p |
|
YKR093W | 8.35 |
PTR2
|
Integral membrane peptide transporter, mediates transport of di- and tri-peptides; conserved protein that contains 12 transmembrane domains; PTR2 expression is regulated by the N-end rule pathway via repression by Cup9p |
|
YDR044W | 8.33 |
HEM13
|
Coproporphyrinogen III oxidase, an oxygen requiring enzyme that catalyzes the sixth step in the heme biosynthetic pathway; localizes to the mitochondrial inner membrane; transcription is repressed by oxygen and heme (via Rox1p and Hap1p) |
|
YIL056W | 7.98 |
VHR1
|
Transcriptional activator, required for the vitamin H-responsive element (VHRE) mediated induction of VHT1 (Vitamin H transporter) and BIO5 (biotin biosynthesis intermediate transporter) in response to low biotin concentrations |
|
YGR148C | 7.84 |
RPL24B
|
Ribosomal protein L30 of the large (60S) ribosomal subunit, nearly identical to Rpl24Ap and has similarity to rat L24 ribosomal protein; not essential for translation but may be required for normal translation rate |
|
YML056C | 7.84 |
IMD4
|
Inosine monophosphate dehydrogenase, catalyzes the first step of GMP biosynthesis, member of a four-gene family in S. cerevisiae, constitutively expressed |
|
YGR249W | 7.74 |
MGA1
|
Protein similar to heat shock transcription factor; multicopy suppressor of pseudohyphal growth defects of ammonium permease mutants |
|
YOL085C | 7.21 |
Dubious open reading frame unlikely to encode a protein, based on experimental and comparative sequence data; partially overlaps the dubious gene YOL085W-A |
||
YHR181W | 7.17 |
SVP26
|
Integral membrane protein of the early Golgi apparatus and endoplasmic reticulum, involved in COP II vesicle transport; may also function to promote retention of proteins in the early Golgi compartment |
|
YKL152C | 7.11 |
GPM1
|
Tetrameric phosphoglycerate mutase, mediates the conversion of 3-phosphoglycerate to 2-phosphoglycerate during glycolysis and the reverse reaction during gluconeogenesis |
|
YJR145C | 7.08 |
RPS4A
|
Protein component of the small (40S) ribosomal subunit; mutation affects 20S pre-rRNA processing; identical to Rps4Bp and has similarity to rat S4 ribosomal protein |
|
YPL250W-A | 6.97 |
Identified by fungal homology and RT-PCR |
||
YOR175C | 6.96 |
ALE1
|
Lysophospholipid acyltransferase, partially redundant with Slc1p; part of MBOAT family of membrane-bound O-acyltransferases; key component of Lands cycle; may have role in fatty acid exchange at sn-2 position of mature glycerophospholipids |
|
YDL047W | 6.92 |
SIT4
|
Type 2A-related serine-threonine phosphatase that functions in the G1/S transition of the mitotic cycle; cytoplasmic and nuclear protein that modulates functions mediated by Pkc1p including cell wall and actin cytoskeleton organization |
|
YBR126W-A | 6.82 |
Dubious ORF unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the dubious ORF YBR126W-B; identified by gene-trapping, microarray analysis, and genome-wide homology searches |
||
YKL110C | 6.81 |
KTI12
|
Protein that plays a role, with Elongator complex, in modification of wobble nucleosides in tRNA; involved in sensitivity to G1 arrest induced by zymocin; interacts with chromatin throughout the genome; also interacts with Cdc19p |
|
YNR018W | 6.74 |
AIM38
|
Putative protein of unknown function; non-tagged protein is detected in purified mitochondria; null mutant displays decreased frequency of mitochondrial genome loss (petite formation) and severe growth defect in minimal glycerol media |
|
YLR437C | 6.70 |
Putative protein of unknown function; epitope tagged protein localizes to the cytoplasm |
||
YGR279C | 6.66 |
SCW4
|
Cell wall protein with similarity to glucanases; scw4 scw10 double mutants exhibit defects in mating |
|
YOR063W | 6.65 |
RPL3
|
Protein component of the large (60S) ribosomal subunit, has similarity to E. coli L3 and rat L3 ribosomal proteins; involved in the replication and maintenance of killer double stranded RNA virus |
|
YDR384C | 6.61 |
ATO3
|
Plasma membrane protein, regulation pattern suggests a possible role in export of ammonia from the cell; phosphorylated in mitochondria; member of the TC 9.B.33 YaaH family of putative transporters |
|
YCL064C | 6.47 |
CHA1
|
Catabolic L-serine (L-threonine) deaminase, catalyzes the degradation of both L-serine and L-threonine; required to use serine or threonine as the sole nitrogen source, transcriptionally induced by serine and threonine |
|
YDR508C | 6.42 |
GNP1
|
High-affinity glutamine permease, also transports Leu, Ser, Thr, Cys, Met and Asn; expression is fully dependent on Grr1p and modulated by the Ssy1p-Ptr3p-Ssy5p (SPS) sensor of extracellular amino acids |
|
YDR509W | 6.37 |
Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data |
||
YHR203C | 6.26 |
RPS4B
|
Protein component of the small (40S) ribosomal subunit; identical to Rps4Ap and has similarity to rat S4 ribosomal protein |
|
YNR001W-A | 6.23 |
Dubious open reading frame unlikely to encode a functional protein; identified by homology |
||
YML075C | 5.99 |
HMG1
|
One of two isozymes of HMG-CoA reductase that catalyzes the conversion of HMG-CoA to mevalonate, which is a rate-limiting step in sterol biosynthesis; localizes to the nuclear envelope; overproduction induces the formation of karmellae |
|
YKR038C | 5.94 |
KAE1
|
Putative glycoprotease proposed to be in transcription as a component of the EKC protein complex with Bud32p, Cgi121p, Pcc1p, and Gon7p; also identified as a component of the KEOPS protein complex |
|
YMR183C | 5.91 |
SSO2
|
Plasma membrane t-SNARE involved in fusion of secretory vesicles at the plasma membrane; syntaxin homolog that is functionally redundant with Sso1p |
|
YGL077C | 5.80 |
HNM1
|
Choline/ethanolamine transporter; involved in the uptake of nitrogen mustard and the uptake of glycine betaine during hypersaline stress; co-regulated with phospholipid biosynthetic genes and negatively regulated by choline and myo-inositol |
|
YMR217W | 5.78 |
GUA1
|
GMP synthase, an enzyme that catalyzes the second step in the biosynthesis of GMP from inosine 5'-phosphate (IMP); transcription is not subject to regulation by guanine but is negatively regulated by nutrient starvation |
|
YKL181W | 5.77 |
PRS1
|
5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase, synthesizes PRPP, which is required for nucleotide, histidine, and tryptophan biosynthesis; one of five related enzymes, which are active as heteromultimeric complexes |
|
YFR054C | 5.71 |
Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data |
||
YNL300W | 5.70 |
Glycosylphosphatidylinositol-dependent cell wall protein, expression is periodic and decreases in respone to ergosterol perturbation or upon entry into stationary phase; depletion increases resistance to lactic acid |
||
YHR094C | 5.69 |
HXT1
|
Low-affinity glucose transporter of the major facilitator superfamily, expression is induced by Hxk2p in the presence of glucose and repressed by Rgt1p when glucose is limiting |
|
YIL053W | 5.69 |
RHR2
|
Constitutively expressed isoform of DL-glycerol-3-phosphatase; involved in glycerol biosynthesis, induced in response to both anaerobic and, along with the Hor2p/Gpp2p isoform, osmotic stress |
|
YCR031C | 5.68 |
RPS14A
|
Ribosomal protein 59 of the small subunit, required for ribosome assembly and 20S pre-rRNA processing; mutations confer cryptopleurine resistance; nearly identical to Rps14Bp and similar to E. coli S11 and rat S14 ribosomal proteins |
|
YDR025W | 5.58 |
RPS11A
|
Protein component of the small (40S) ribosomal subunit; identical to Rps11Bp and has similarity to E. coli S17 and rat S11 ribosomal proteins |
|
YNL301C | 5.57 |
RPL18B
|
Protein component of the large (60S) ribosomal subunit, identical to Rpl18Ap and has similarity to rat L18 ribosomal protein |
|
YDR002W | 5.57 |
YRB1
|
Ran GTPase binding protein; involved in nuclear protein import and RNA export, ubiquitin-mediated protein degradation during the cell cycle; shuttles between the nucleus and cytoplasm; is essential; homolog of human RanBP1 |
|
YDR098C | 5.46 |
GRX3
|
Hydroperoxide and superoxide-radical responsive glutathione-dependent oxidoreductase; monothiol glutaredoxin subfamily member along with Grx4p and Grx5p; protects cells from oxidative damage |
|
YGL179C | 5.44 |
TOS3
|
Protein kinase, related to and functionally redundant with Elm1p and Sak1p for the phosphorylation and activation of Snf1p; functionally orthologous to LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome |
|
YGR118W | 5.37 |
RPS23A
|
Ribosomal protein 28 (rp28) of the small (40S) ribosomal subunit, required for translational accuracy; nearly identical to Rps23Bp and similar to E. coli S12 and rat S23 ribosomal proteins; deletion of both RPS23A and RPS23B is lethal |
|
YMR049C | 5.29 |
ERB1
|
Protein required for maturation of the 25S and 5.8S ribosomal RNAs; constituent of 66S pre-ribosomal particles; homologous to mammalian Bop1 |
|
YGL126W | 5.29 |
SCS3
|
Protein required for inositol prototrophy, identified as an ortholog of the FIT family of proteins involved in triglyceride droplet biosynthesis; disputed role in the synthesis of inositol phospholipids from inositol |
|
YNL079C | 5.28 |
TPM1
|
Major isoform of tropomyosin; binds to and stabilizes actin cables and filaments, which direct polarized cell growth and the distribution of several organelles; acetylated by the NatB complex and acetylated form binds actin most efficiently |
|
YNL078W | 5.27 |
NIS1
|
Protein localized in the bud neck at G2/M phase; physically interacts with septins; possibly involved in a mitotic signaling network |
|
YAL033W | 5.23 |
POP5
|
Subunit of both RNase MRP, which cleaves pre-rRNA, and nuclear RNase P, which cleaves tRNA precursors to generate mature 5' ends |
|
YPL014W | 5.20 |
Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and to the nucleus |
||
YGR052W | 5.15 |
FMP48
|
Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; induced by treatment with 8-methoxypsoralen and UVA irradiation |
|
YDR353W | 5.13 |
TRR1
|
Cytoplasmic thioredoxin reductase, key regulatory enzyme that determines the redox state of the thioredoxin system, which acts as a disulfide reductase system and protects cells against both oxidative and reductive stress |
|
YMR106C | 5.10 |
YKU80
|
Subunit of the telomeric Ku complex (Yku70p-Yku80p), involved in telomere length maintenance, structure and telomere position effect; relocates to sites of double-strand cleavage to promote nonhomologous end joining during DSB repair |
|
YCL063W | 5.09 |
VAC17
|
Protein involved in vacuole inheritance; acts as a vacuole-specific receptor for myosin Myo2p |
|
YKL065C | 5.08 |
YET1
|
Endoplasmic reticulum transmembrane protein; may interact with ribosomes, based on co-purification experiments; homolog of human BAP31 protein |
|
YGL209W | 5.03 |
MIG2
|
Protein containing zinc fingers, involved in repression, along with Mig1p, of SUC2 (invertase) expression by high levels of glucose; binds to Mig1p-binding sites in SUC2 promoter |
|
YBL092W | 5.01 |
RPL32
|
Protein component of the large (60S) ribosomal subunit, has similarity to rat L32 ribosomal protein; overexpression disrupts telomeric silencing |
|
YNR054C | 4.99 |
ESF2
|
Essential nucleolar protein involved in pre-18S rRNA processing; binds to RNA and stimulates ATPase activity of Dbp8; involved in assembly of the small subunit (SSU) processome |
|
YOR050C | 4.96 |
Hypothetical protein |
||
YJL107C | 4.96 |
Putative protein of unknown function; expression is induced by activation of the HOG1 mitogen-activated signaling pathway and this induction is Hog1p/Pbs2p dependent; YJL107C and adjacent ORF, YJL108C are merged in related fungi |
||
YJL200C | 4.92 |
ACO2
|
Putative mitochondrial aconitase isozyme; similarity to Aco1p, an aconitase required for the TCA cycle; expression induced during growth on glucose, by amino acid starvation via Gcn4p, and repressed on ethanol |
|
YIL096C | 4.86 |
Putative protein of unknown function; associates with precursors of the 60S ribosomal subunit |
||
YBR126C | 4.85 |
TPS1
|
Synthase subunit of trehalose-6-phosphate synthase/phosphatase complex, which synthesizes the storage carbohydrate trehalose; also found in a monomeric form; expression is induced by the stress response and repressed by the Ras-cAMP pathway |
|
YKR094C | 4.85 |
RPL40B
|
Fusion protein, identical to Rpl40Ap, that is cleaved to yield ubiquitin and a ribosomal protein of the large (60S) ribosomal subunit with similarity to rat L40; ubiquitin may facilitate assembly of the ribosomal protein into ribosomes |
|
YPL245W | 4.85 |
Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to both the nucleus and the cytoplasm |
||
YGR192C | 4.78 |
TDH3
|
Glyceraldehyde-3-phosphate dehydrogenase, isozyme 3, involved in glycolysis and gluconeogenesis; tetramer that catalyzes the reaction of glyceraldehyde-3-phosphate to 1,3 bis-phosphoglycerate; detected in the cytoplasm and cell-wall |
|
YBR118W | 4.76 |
TEF2
|
Translational elongation factor EF-1 alpha; also encoded by TEF1; functions in the binding reaction of aminoacyl-tRNA (AA-tRNA) to ribosomes |
|
YLR048W | 4.74 |
RPS0B
|
Protein component of the small (40S) ribosomal subunit, nearly identical to Rps0Ap; required for maturation of 18S rRNA along with Rps0Ap; deletion of either RPS0 gene reduces growth rate, deletion of both genes is lethal |
|
YHR216W | 4.69 |
IMD2
|
Inosine monophosphate dehydrogenase, catalyzes the first step of GMP biosynthesis, expression is induced by mycophenolic acid resulting in resistance to the drug, expression is repressed by nutrient limitation |
|
YGR234W | 4.65 |
YHB1
|
Nitric oxide oxidoreductase, flavohemoglobin involved in nitric oxide detoxification; plays a role in the oxidative and nitrosative stress responses |
|
YHR193C | 4.64 |
EGD2
|
Alpha subunit of the heteromeric nascent polypeptide-associated complex (NAC) involved in protein sorting and translocation, associated with cytoplasmic ribosomes |
|
YGR285C | 4.64 |
ZUO1
|
Cytosolic ribosome-associated chaperone that acts, together with Ssz1p and the Ssb proteins, as a chaperone for nascent polypeptide chains; contains a DnaJ domain and functions as a J-protein partner for Ssb1p and Ssb2p |
|
YOL155C | 4.64 |
HPF1
|
Haze-protective mannoprotein that reduces the particle size of aggregated proteins in white wines |
|
YPL037C | 4.63 |
EGD1
|
Subunit beta1 of the nascent polypeptide-associated complex (NAC) involved in protein targeting, associated with cytoplasmic ribosomes; enhances DNA binding of the Gal4p activator; homolog of human BTF3b |
|
YOL012C | 4.61 |
HTZ1
|
Histone variant H2AZ, exchanged for histone H2A in nucleosomes by the SWR1 complex; involved in transcriptional regulation through prevention of the spread of silent heterochromatin |
|
YIL052C | 4.61 |
RPL34B
|
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl34Ap and has similarity to rat L34 ribosomal protein |
|
YBR175W | 4.61 |
SWD3
|
Essential subunit of the COMPASS (Set1C) complex, which methylates histone H3 on lysine 4 and is required in transcriptional silencing near telomeres; WD40 beta propeller superfamily member and ortholog of mammalian WDR5 |
|
YBR162C | 4.58 |
TOS1
|
Covalently-bound cell wall protein of unknown function; identified as a cell cycle regulated SBF target gene; deletion mutants are highly resistant to treatment with beta-1,3-glucanase; has sequence similarity to YJL171C |
|
YBR174C | 4.55 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF YBR175W; null mutant is viable and sporulation defective |
||
YMR307W | 4.53 |
GAS1
|
Beta-1,3-glucanosyltransferase, required for cell wall assembly; localizes to the cell surface via a glycosylphosphatidylinositol (GPI) anchor |
|
YML074C | 4.52 |
FPR3
|
Nucleolar peptidyl-prolyl cis-trans isomerase (PPIase); FK506 binding protein; phosphorylated by casein kinase II (Cka1p-Cka2p-Ckb1p-Ckb2p) and dephosphorylated by Ptp1p |
|
YBL032W | 4.44 |
HEK2
|
RNA binding protein with similarity to hnRNP-K that localizes to the cytoplasm and to subtelomeric DNA; required for the proper localization of ASH1 mRNA; involved in the regulation of telomere position effect and telomere length |
|
YDR037W | 4.44 |
KRS1
|
Lysyl-tRNA synthetase; also identified as a negative regulator of general control of amino acid biosynthesis |
|
YDR399W | 4.40 |
HPT1
|
Dimeric hypoxanthine-guanine phosphoribosyltransferase, catalyzes the formation of both inosine monophosphate and guanosine monophosphate; mutations in the human homolog HPRT1 can cause Lesch-Nyhan syndrome and Kelley-Seegmiller syndrome |
|
YBR210W | 4.40 |
ERV15
|
Protein involved in export of proteins from the endoplasmic reticulum, has similarity to Erv14p |
|
YGR242W | 4.39 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF YAP1802/YGR241C |
||
YJL198W | 4.32 |
PHO90
|
Low-affinity phosphate transporter; deletion of pho84, pho87, pho89, pho90, and pho91 causes synthetic lethality; transcription independent of Pi and Pho4p activity; overexpression results in vigorous growth |
|
YJR114W | 4.31 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF RSM7/YJR113C |
||
YPR119W | 4.31 |
CLB2
|
B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the transition from G2 to M phase; accumulates during G2 and M, then targeted via a destruction box motif for ubiquitin-mediated degradation by the proteasome |
|
YHR020W | 4.27 |
Protein of unknown function that may interact with ribosomes, based on co-purification experiments; has similarity to proline-tRNA ligase; YHR020W is an essential gene |
||
YGR055W | 4.25 |
MUP1
|
High affinity methionine permease, integral membrane protein with 13 putative membrane-spanning regions; also involved in cysteine uptake |
|
YGR040W | 4.20 |
KSS1
|
Mitogen-activated protein kinase (MAPK) involved in signal transduction pathways that control filamentous growth and pheromone response; the KSS1 gene is nonfunctional in S288C strains and functional in W303 strains |
|
YAL040C | 4.20 |
CLN3
|
G1 cyclin involved in cell cycle progression; activates Cdc28p kinase to promote the G1 to S phase transition; plays a role in regulating transcription of the other G1 cyclins, CLN1 and CLN2; regulated by phosphorylation and proteolysis |
|
YDL241W | 4.18 |
Putative protein of unknown function; YDL241W is not an essential gene |
||
YIL016W | 4.10 |
SNL1
|
Protein of unknown function proposed to be involved in nuclear pore complex biogenesis and maintenance as well as protein folding; has similarity to the mammalian BAG-1 protein |
|
YMR199W | 4.09 |
CLN1
|
G1 cyclin involved in regulation of the cell cycle; activates Cdc28p kinase to promote the G1 to S phase transition; late G1 specific expression depends on transcription factor complexes, MBF (Swi6p-Mbp1p) and SBF (Swi6p-Swi4p) |
|
YGR180C | 4.08 |
RNR4
|
Ribonucleotide-diphosphate reductase (RNR), small subunit; the RNR complex catalyzes the rate-limiting step in dNTP synthesis and is regulated by DNA replication and DNA damage checkpoint pathways via localization of the small subunits |
|
YHR180W-A | 4.06 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps dubious ORF YHR180C-B and long terminal repeat YHRCsigma3 |
||
YDR041W | 4.01 |
RSM10
|
Mitochondrial ribosomal protein of the small subunit, has similarity to E. coli S10 ribosomal protein; essential for viability, unlike most other mitoribosomal proteins |
|
YGR189C | 4.00 |
CRH1
|
Putative chitin transglycosidase, cell wall protein that functions in the transfer of chitin to beta(1-6)glucan; localizes to sites of polarized growth; expression is induced under cell wall stress conditions |
|
YMR208W | 4.00 |
ERG12
|
Mevalonate kinase, acts in the biosynthesis of isoprenoids and sterols, including ergosterol, from mevalonate |
|
YOR096W | 3.97 |
RPS7A
|
Protein component of the small (40S) ribosomal subunit, nearly identical to Rps7Bp; interacts with Kti11p; deletion causes hypersensitivity to zymocin; has similarity to rat S7 and Xenopus S8 ribosomal proteins |
|
YBR066C | 3.97 |
NRG2
|
Transcriptional repressor that mediates glucose repression and negatively regulates filamentous growth; has similarity to Nrg1p |
|
YGR155W | 3.93 |
CYS4
|
Cystathionine beta-synthase, catalyzes the synthesis of cystathionine from serine and homocysteine, the first committed step in cysteine biosynthesis |
|
YGR241C | 3.89 |
YAP1802
|
Protein involved in clathrin cage assembly; binds Pan1p and clathrin; homologous to Yap1801p, member of the AP180 protein family |
|
YDL191W | 3.88 |
RPL35A
|
Protein component of the large (60S) ribosomal subunit, identical to Rpl35Bp and has similarity to rat L35 ribosomal protein |
|
YLR028C | 3.85 |
ADE16
|
Enzyme of 'de novo' purine biosynthesis containing both 5-aminoimidazole-4-carboxamide ribonucleotide transformylase and inosine monophosphate cyclohydrolase activities, isozyme of Ade17p; ade16 ade17 mutants require adenine and histidine |
|
YPR170W-B | 3.82 |
Putative protein of unknown function, conserved in fungi; partially overlaps the dubious genes YPR169W-A, YPR170W-A and YRP170C |
||
YJR113C | 3.81 |
RSM7
|
Mitochondrial ribosomal protein of the small subunit, has similarity to E. coli S7 ribosomal protein |
|
YOR247W | 3.80 |
SRL1
|
Mannoprotein that exhibits a tight association with the cell wall, required for cell wall stability in the absence of GPI-anchored mannoproteins; has a high serine-threonine content; expression is induced in cell wall mutants |
|
YKL096W-A | 3.78 |
CWP2
|
Covalently linked cell wall mannoprotein, major constituent of the cell wall; plays a role in stabilizing the cell wall; involved in low pH resistance; precursor is GPI-anchored |
|
YGR050C | 3.77 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data |
||
YNL160W | 3.76 |
YGP1
|
Cell wall-related secretory glycoprotein; induced by nutrient deprivation-associated growth arrest and upon entry into stationary phase; may be involved in adaptation prior to stationary phase entry; has similarity to Sps100p |
|
YBR189W | 3.75 |
RPS9B
|
Protein component of the small (40S) ribosomal subunit; nearly identical to Rps9Ap and has similarity to E. coli S4 and rat S9 ribosomal proteins |
|
YPL010W | 3.72 |
RET3
|
Zeta subunit of the coatomer complex (COPI), which coats Golgi-derived transport vesicles; involved in retrograde transport between Golgi and ER |
|
YML073C | 3.71 |
RPL6A
|
N-terminally acetylated protein component of the large (60S) ribosomal subunit, has similarity to Rpl6Bp and to rat L6 ribosomal protein; binds to 5.8S rRNA |
|
YOR376W-A | 3.68 |
Putative protein of unknown function; identified by fungal homology and RT-PCR |
||
YDR534C | 3.68 |
FIT1
|
Mannoprotein that is incorporated into the cell wall via a glycosylphosphatidylinositol (GPI) anchor, involved in the retention of siderophore-iron in the cell wall |
|
YJR105W | 3.66 |
ADO1
|
Adenosine kinase, required for the utilization of S-adenosylmethionine (AdoMet); may be involved in recycling adenosine produced through the methyl cycle |
|
YOL124C | 3.64 |
TRM11
|
Catalytic subunit of an adoMet-dependent tRNA methyltransferase complex (Trm11p-Trm112p), required for the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNAs; contains a THUMP domain and a methyltransferase domain |
|
YLR060W | 3.62 |
FRS1
|
Beta subunit of cytoplasmic phenylalanyl-tRNA synthetase, forms a tetramer with Frs2p to generate active enzyme; sequence is evolutionarily distant from mitochondrial phenylalanyl-tRNA synthetase (Msf1p), but substrate binding is similar |
|
YGR229C | 3.59 |
SMI1
|
Protein involved in the regulation of cell wall synthesis; proposed to be involved in coordinating cell cycle progression with cell wall integrity |
|
YKL030W | 3.59 |
Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; partially overlaps the verified gene MAE1 |
||
YLR249W | 3.50 |
YEF3
|
Translational elongation factor 3, stimulates the binding of aminoacyl-tRNA (AA-tRNA) to ribosomes by releasing EF-1 alpha from the ribosomal complex; contains two ABC cassettes; binds and hydrolyses ATP |
|
YER137C | 3.48 |
Putative protein of unknown function |
||
YLR150W | 3.47 |
STM1
|
Protein that binds G4 quadruplex and purine motif triplex nucleic acid; acts with Cdc13p to maintain telomere structure; interacts with ribosomes and subtelomeric Y' DNA; multicopy suppressor of tom1 and pop2 mutations |
|
YDR040C | 3.47 |
ENA1
|
P-type ATPase sodium pump, involved in Na+ and Li+ efflux to allow salt tolerance |
|
YGR195W | 3.44 |
SKI6
|
3'-to-5' phosphorolytic exoribonuclease that is a subunit of the exosome; required for 3' processing of the 5.8S rRNA; involved in 3' to 5' mRNA degradation and translation inhibition of non-poly(A) mRNAs |
|
YHR019C | 3.43 |
DED81
|
Cytosolic asparaginyl-tRNA synthetase, required for protein synthesis, catalyzes the specific attachment of asparagine to its cognate tRNA |
|
YHR067W | 3.43 |
HTD2
|
Mitochondrial 3-hydroxyacyl-thioester dehydratase involved in fatty acid biosynthesis, required for respiratory growth and for normal mitochondrial morphology |
|
YHR052W | 3.43 |
CIC1
|
Essential protein that interacts with proteasome components and has a potential role in proteasome substrate specificity; also copurifies with 66S pre-ribosomal particles |
|
YDR517W | 3.43 |
GRH1
|
Acetylated, cis-golgi localized protein involved in ER to Golgi transport; homolog of human GRASP65; forms a complex with the coiled-coil protein Bug1p; mutants are compromised for the fusion of ER-derived vesicles with Golgi membranes |
|
YDR094W | 3.41 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps verified ORF DNF2 |
||
YIL018W | 3.40 |
RPL2B
|
Protein component of the large (60S) ribosomal subunit, identical to Rpl2Ap and has similarity to E. coli L2 and rat L8 ribosomal proteins; expression is upregulated at low temperatures |
|
YBL039C | 3.39 |
URA7
|
Major CTP synthase isozyme (see also URA8), catalyzes the ATP-dependent transfer of the amide nitrogen from glutamine to UTP, forming CTP, the final step in de novo biosynthesis of pyrimidines; involved in phospholipid biosynthesis |
|
YMR032W | 3.39 |
HOF1
|
Bud neck-localized, SH3 domain-containing protein required for cytokinesis; regulates actomyosin ring dynamics and septin localization; interacts with the formins, Bni1p and Bnr1p, and with Cyk3p, Vrp1p, and Bni5p |
|
YGR181W | 3.34 |
TIM13
|
Mitochondrial intermembrane space protein, forms a complex with TIm8p that mediates import and insertion of a subset of polytopic inner membrane proteins; may prevent aggregation of incoming proteins in a chaperone-like manner |
|
YOL011W | 3.33 |
PLB3
|
Phospholipase B (lysophospholipase) involved in phospholipid metabolism; hydrolyzes phosphatidylinositol and phosphatidylserine and displays transacylase activity in vitro |
|
YOR314W | 3.32 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data |
||
YKR013W | 3.32 |
PRY2
|
Protein of unknown function, has similarity to Pry1p and Pry3p and to the plant PR-1 class of pathogen related proteins |
|
YPL238C | 3.29 |
Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps 5' end of the verified essential gene SUI3/YPL237W |
||
YER130C | 3.28 |
Hypothetical protein |
||
YGR261C | 3.28 |
APL6
|
Beta3-like subunit of the yeast AP-3 complex; functions in transport of alkaline phosphatase to the vacuole via the alternate pathway; exists in both cytosolic and peripherally associated membrane-bound pools |
|
YGL225W | 3.27 |
VRG4
|
Golgi GDP-mannose transporter; regulates Golgi function and glycosylation in Golgi |
|
YDR033W | 3.27 |
MRH1
|
Protein that localizes primarily to the plasma membrane, also found at the nuclear envelope; the authentic, non-tagged protein is detected in mitochondria in a phosphorylated state; has similarity to Hsp30p and Yro2p |
|
YJL106W | 3.25 |
IME2
|
Serine/threonine protein kinase involved in activation of meiosis, associates with Ime1p and mediates its stability, activates Ndt80p; IME2 expression is positively regulated by Ime1p |
|
YNR016C | 3.19 |
ACC1
|
Acetyl-CoA carboxylase, biotin containing enzyme that catalyzes the carboxylation of acetyl-CoA to form malonyl-CoA; required for de novo biosynthesis of long-chain fatty acids |
|
YOR107W | 3.17 |
RGS2
|
Negative regulator of glucose-induced cAMP signaling; directly activates the GTPase activity of the heterotrimeric G protein alpha subunit Gpa2p |
|
YKL153W | 3.16 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; transcription of both YLK153W and the overlapping essential gene GPM1 is reduced in the gcr1 null mutant |
||
YDR074W | 3.10 |
TPS2
|
Phosphatase subunit of the trehalose-6-phosphate synthase/phosphatase complex, which synthesizes the storage carbohydrate trehalose; expression is induced by stress conditions and repressed by the Ras-cAMP pathway |
|
YFL015C | 3.08 |
Dubious open reading frame unlikely to encode a protein; partially overlaps dubious ORF YFL015W-A; YFL015C is not an essential gene |
||
YJL190C | 3.08 |
RPS22A
|
Protein component of the small (40S) ribosomal subunit; nearly identical to Rps22Bp and has similarity to E. coli S8 and rat S15a ribosomal proteins |
|
YOL103W | 3.07 |
ITR2
|
Myo-inositol transporter with strong similarity to the major myo-inositol transporter Itr1p, member of the sugar transporter superfamily; expressed constitutively |
|
YER102W | 3.06 |
RPS8B
|
Protein component of the small (40S) ribosomal subunit; identical to Rps8Ap and has similarity to rat S8 ribosomal protein |
|
YDR095C | 3.06 |
Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data |
||
YER031C | 3.06 |
YPT31
|
GTPase of the Ypt/Rab family, very similar to Ypt32p; involved in the exocytic pathway; mediates intra-Golgi traffic or the budding of post-Golgi vesicles from the trans-Golgi |
|
YBR106W | 3.04 |
PHO88
|
Probable membrane protein, involved in phosphate transport; pho88 pho86 double null mutant exhibits enhanced synthesis of repressible acid phosphatase at high inorganic phosphate concentrations |
|
YDL048C | 3.03 |
STP4
|
Protein containing a Kruppel-type zinc-finger domain; has similarity to Stp1p, Stp2p, and Stp3p |
|
YFL015W-A | 3.03 |
Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data |
||
YLR132C | 2.98 |
Protein of unknown function; green fluorescent protein (GFP)-tagged protein localizes to mitochondria and nucleus; YLR132C is an essential gene |
||
YLR300W | 2.97 |
EXG1
|
Major exo-1,3-beta-glucanase of the cell wall, involved in cell wall beta-glucan assembly; exists as three differentially glycosylated isoenzymes |
|
YJL196C | 2.95 |
ELO1
|
Elongase I, medium-chain acyl elongase, catalyzes carboxy-terminal elongation of unsaturated C12-C16 fatty acyl-CoAs to C16-C18 fatty acids |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
10.9 | 32.8 | GO:0000098 | sulfur amino acid catabolic process(GO:0000098) |
10.1 | 30.2 | GO:0019673 | GDP-mannose biosynthetic process(GO:0009298) GDP-mannose metabolic process(GO:0019673) |
9.1 | 99.8 | GO:0007109 | obsolete cytokinesis, completion of separation(GO:0007109) |
5.1 | 35.7 | GO:0043137 | DNA replication, removal of RNA primer(GO:0043137) |
4.7 | 14.2 | GO:0006432 | phenylalanyl-tRNA aminoacylation(GO:0006432) |
4.5 | 22.7 | GO:0006177 | GMP biosynthetic process(GO:0006177) |
4.3 | 12.9 | GO:0043484 | regulation of RNA splicing(GO:0043484) regulation of mRNA splicing, via spliceosome(GO:0048024) |
4.2 | 16.8 | GO:0000461 | endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000461) |
3.6 | 10.7 | GO:0045901 | positive regulation of translational elongation(GO:0045901) |
3.0 | 12.2 | GO:0009240 | isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287) isopentenyl diphosphate metabolic process(GO:0046490) |
2.8 | 11.4 | GO:0000771 | agglutination involved in conjugation with cellular fusion(GO:0000752) agglutination involved in conjugation(GO:0000771) heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157) cell-cell adhesion(GO:0098609) adhesion between unicellular organisms(GO:0098610) multi organism cell adhesion(GO:0098740) cell-cell adhesion via plasma-membrane adhesion molecules(GO:0098742) |
2.5 | 7.5 | GO:0006567 | threonine catabolic process(GO:0006567) |
2.5 | 9.9 | GO:0090337 | regulation of formin-nucleated actin cable assembly(GO:0090337) positive regulation of formin-nucleated actin cable assembly(GO:0090338) |
2.0 | 14.0 | GO:0006007 | glucose catabolic process(GO:0006007) glycolytic fermentation to ethanol(GO:0019655) glycolytic fermentation(GO:0019660) hexose catabolic process to ethanol(GO:1902707) |
2.0 | 13.9 | GO:0010696 | positive regulation of spindle pole body separation(GO:0010696) |
2.0 | 23.4 | GO:0000917 | barrier septum assembly(GO:0000917) cell septum assembly(GO:0090529) |
1.9 | 5.8 | GO:0009186 | deoxyribonucleoside diphosphate metabolic process(GO:0009186) |
1.9 | 29.8 | GO:0051029 | rRNA export from nucleus(GO:0006407) rRNA transport(GO:0051029) |
1.9 | 9.3 | GO:0051083 | 'de novo' cotranslational protein folding(GO:0051083) |
1.7 | 5.2 | GO:0038032 | termination of signal transduction(GO:0023021) termination of G-protein coupled receptor signaling pathway(GO:0038032) |
1.7 | 8.7 | GO:0001676 | long-chain fatty acid metabolic process(GO:0001676) |
1.6 | 14.3 | GO:0042219 | cellular modified amino acid catabolic process(GO:0042219) |
1.4 | 5.7 | GO:0036170 | filamentous growth of a population of unicellular organisms in response to starvation(GO:0036170) regulation of filamentous growth of a population of unicellular organisms in response to starvation(GO:1900434) positive regulation of filamentous growth of a population of unicellular organisms in response to starvation(GO:1900436) |
1.4 | 19.1 | GO:0000028 | ribosomal small subunit assembly(GO:0000028) |
1.4 | 5.4 | GO:0045048 | protein insertion into ER membrane(GO:0045048) |
1.3 | 9.3 | GO:0005992 | trehalose biosynthetic process(GO:0005992) oligosaccharide biosynthetic process(GO:0009312) disaccharide biosynthetic process(GO:0046351) |
1.3 | 5.1 | GO:0009423 | chorismate biosynthetic process(GO:0009423) |
1.2 | 6.2 | GO:0072337 | modified amino acid transport(GO:0072337) |
1.2 | 8.6 | GO:0006782 | protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501) |
1.2 | 3.6 | GO:0000101 | sulfur amino acid transport(GO:0000101) |
1.2 | 4.8 | GO:0000296 | spermine transport(GO:0000296) |
1.2 | 8.4 | GO:0043457 | regulation of cellular respiration(GO:0043457) |
1.2 | 4.8 | GO:0019346 | transsulfuration(GO:0019346) |
1.2 | 8.4 | GO:0042938 | dipeptide transport(GO:0042938) |
1.2 | 3.5 | GO:0043066 | negative regulation of apoptotic process(GO:0043066) negative regulation of programmed cell death(GO:0043069) negative regulation of cell death(GO:0060548) |
1.2 | 5.8 | GO:0046391 | 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391) |
1.1 | 142.8 | GO:0002181 | cytoplasmic translation(GO:0002181) |
1.1 | 5.5 | GO:0007535 | donor selection(GO:0007535) |
1.1 | 8.7 | GO:0000372 | Group I intron splicing(GO:0000372) RNA splicing, via transesterification reactions with guanosine as nucleophile(GO:0000376) |
1.1 | 14.1 | GO:0006450 | regulation of translational fidelity(GO:0006450) |
1.0 | 2.0 | GO:0033559 | unsaturated fatty acid biosynthetic process(GO:0006636) unsaturated fatty acid metabolic process(GO:0033559) |
1.0 | 1.0 | GO:0014070 | response to organic cyclic compound(GO:0014070) response to cycloheximide(GO:0046898) |
1.0 | 3.9 | GO:0030497 | fatty acid elongation(GO:0030497) |
1.0 | 5.7 | GO:0007030 | Golgi organization(GO:0007030) |
0.9 | 2.8 | GO:0006114 | glycerol biosynthetic process(GO:0006114) alditol biosynthetic process(GO:0019401) |
0.9 | 8.3 | GO:0006814 | sodium ion transport(GO:0006814) |
0.9 | 7.2 | GO:0033014 | porphyrin-containing compound biosynthetic process(GO:0006779) heme biosynthetic process(GO:0006783) tetrapyrrole biosynthetic process(GO:0033014) |
0.9 | 13.4 | GO:0001100 | negative regulation of exit from mitosis(GO:0001100) |
0.9 | 3.5 | GO:0018196 | peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279) |
0.9 | 2.6 | GO:0043171 | peptide catabolic process(GO:0043171) |
0.9 | 5.3 | GO:0007119 | budding cell isotropic bud growth(GO:0007119) |
0.9 | 1.7 | GO:0061422 | positive regulation of transcription from RNA polymerase II promoter in response to alkaline pH(GO:0061422) |
0.9 | 3.4 | GO:0034473 | U1 snRNA 3'-end processing(GO:0034473) |
0.8 | 2.5 | GO:0044209 | AMP salvage(GO:0044209) |
0.8 | 2.5 | GO:0009211 | pyrimidine deoxyribonucleoside triphosphate metabolic process(GO:0009211) |
0.8 | 3.3 | GO:1900461 | positive regulation of cell growth(GO:0030307) positive regulation of pseudohyphal growth by positive regulation of transcription from RNA polymerase II promoter(GO:1900461) positive regulation of pseudohyphal growth(GO:2000222) |
0.8 | 2.5 | GO:1904667 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051436) regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051439) negative regulation of ubiquitin protein ligase activity(GO:1904667) |
0.8 | 4.9 | GO:0006646 | phosphatidylethanolamine biosynthetic process(GO:0006646) |
0.8 | 9.7 | GO:0009636 | response to toxic substance(GO:0009636) |
0.8 | 2.4 | GO:0015691 | cadmium ion transport(GO:0015691) |
0.8 | 6.3 | GO:0070525 | tRNA threonylcarbamoyladenosine metabolic process(GO:0070525) |
0.8 | 2.4 | GO:0045338 | terpenoid metabolic process(GO:0006721) terpenoid biosynthetic process(GO:0016114) farnesyl diphosphate biosynthetic process(GO:0045337) farnesyl diphosphate metabolic process(GO:0045338) |
0.8 | 2.3 | GO:0042454 | NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356) ribonucleoside catabolic process(GO:0042454) cytidine metabolic process(GO:0046087) |
0.7 | 4.4 | GO:0048255 | RNA stabilization(GO:0043489) mRNA stabilization(GO:0048255) |
0.7 | 0.7 | GO:0015833 | peptide transport(GO:0015833) |
0.7 | 7.8 | GO:0045053 | protein retention in Golgi apparatus(GO:0045053) |
0.7 | 3.5 | GO:0000162 | tryptophan biosynthetic process(GO:0000162) indole-containing compound biosynthetic process(GO:0042435) indolalkylamine biosynthetic process(GO:0046219) |
0.7 | 3.5 | GO:0015780 | nucleotide-sugar transport(GO:0015780) |
0.7 | 2.7 | GO:0006898 | receptor-mediated endocytosis(GO:0006898) |
0.7 | 3.4 | GO:0006116 | NADH oxidation(GO:0006116) |
0.7 | 1.3 | GO:0015909 | long-chain fatty acid transport(GO:0015909) |
0.7 | 2.6 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
0.7 | 3.3 | GO:0043433 | negative regulation of sequence-specific DNA binding transcription factor activity(GO:0043433) |
0.7 | 2.0 | GO:0042981 | regulation of cell death(GO:0010941) positive regulation of cell death(GO:0010942) regulation of apoptotic process(GO:0042981) positive regulation of apoptotic process(GO:0043065) regulation of programmed cell death(GO:0043067) positive regulation of programmed cell death(GO:0043068) |
0.6 | 14.1 | GO:0002097 | tRNA wobble base modification(GO:0002097) tRNA wobble uridine modification(GO:0002098) |
0.6 | 7.7 | GO:0006037 | cell wall chitin metabolic process(GO:0006037) |
0.6 | 3.8 | GO:0035999 | tetrahydrofolate interconversion(GO:0035999) |
0.6 | 2.5 | GO:0031591 | wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591) |
0.6 | 1.8 | GO:0006003 | fructose 2,6-bisphosphate metabolic process(GO:0006003) |
0.6 | 1.8 | GO:0019419 | sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin)(GO:0019379) sulfate reduction(GO:0019419) |
0.6 | 1.1 | GO:0070637 | nicotinamide riboside metabolic process(GO:0046495) pyridine nucleoside metabolic process(GO:0070637) |
0.6 | 0.6 | GO:0009090 | homoserine biosynthetic process(GO:0009090) |
0.6 | 1.7 | GO:0032108 | negative regulation of macroautophagy(GO:0016242) negative regulation of response to external stimulus(GO:0032102) negative regulation of response to extracellular stimulus(GO:0032105) negative regulation of response to nutrient levels(GO:0032108) |
0.6 | 1.7 | GO:0070475 | rRNA base methylation(GO:0070475) |
0.6 | 2.8 | GO:0044070 | regulation of anion transport(GO:0044070) |
0.6 | 1.7 | GO:0046416 | D-amino acid metabolic process(GO:0046416) |
0.5 | 8.7 | GO:0018208 | protein peptidyl-prolyl isomerization(GO:0000413) peptidyl-proline modification(GO:0018208) |
0.5 | 2.2 | GO:0071406 | response to methylmercury(GO:0051597) cellular response to methylmercury(GO:0071406) |
0.5 | 2.2 | GO:0010674 | negative regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle(GO:0010674) |
0.5 | 1.6 | GO:0030037 | actin filament reorganization involved in cell cycle(GO:0030037) actin filament reorganization(GO:0090527) |
0.5 | 9.6 | GO:0042790 | transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:0042790) |
0.5 | 5.8 | GO:0000921 | septin ring assembly(GO:0000921) |
0.5 | 1.0 | GO:0031532 | actin cytoskeleton reorganization(GO:0031532) |
0.5 | 3.1 | GO:0000743 | nuclear migration involved in conjugation with cellular fusion(GO:0000743) |
0.5 | 1.0 | GO:0010695 | regulation of spindle pole body separation(GO:0010695) |
0.5 | 4.0 | GO:0006549 | isoleucine metabolic process(GO:0006549) |
0.5 | 1.0 | GO:0006734 | NADH metabolic process(GO:0006734) |
0.5 | 1.0 | GO:0032509 | endosome transport via multivesicular body sorting pathway(GO:0032509) |
0.5 | 2.5 | GO:0046459 | short-chain fatty acid metabolic process(GO:0046459) |
0.5 | 1.5 | GO:0007189 | adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189) |
0.5 | 1.0 | GO:0034724 | DNA replication-independent nucleosome organization(GO:0034724) |
0.5 | 1.0 | GO:0071902 | positive regulation of protein serine/threonine kinase activity(GO:0071902) |
0.5 | 4.3 | GO:0031070 | intronic snoRNA processing(GO:0031070) intronic box C/D snoRNA processing(GO:0034965) |
0.5 | 3.3 | GO:0009098 | leucine biosynthetic process(GO:0009098) |
0.5 | 0.9 | GO:0060188 | regulation of protein desumoylation(GO:0060188) |
0.5 | 6.0 | GO:0030488 | tRNA methylation(GO:0030488) |
0.5 | 5.1 | GO:0072593 | reactive oxygen species metabolic process(GO:0072593) |
0.5 | 2.3 | GO:0034476 | U5 snRNA 3'-end processing(GO:0034476) |
0.5 | 1.4 | GO:1900101 | regulation of endoplasmic reticulum unfolded protein response(GO:1900101) |
0.4 | 1.3 | GO:0006343 | establishment of chromatin silencing(GO:0006343) |
0.4 | 4.0 | GO:0034498 | early endosome to Golgi transport(GO:0034498) |
0.4 | 1.3 | GO:0033241 | regulation of cellular amine catabolic process(GO:0033241) |
0.4 | 10.5 | GO:0006890 | retrograde vesicle-mediated transport, Golgi to ER(GO:0006890) |
0.4 | 2.1 | GO:0006491 | N-glycan processing(GO:0006491) |
0.4 | 3.0 | GO:0034063 | stress granule assembly(GO:0034063) |
0.4 | 1.3 | GO:0006654 | phosphatidic acid biosynthetic process(GO:0006654) phosphatidic acid metabolic process(GO:0046473) |
0.4 | 3.4 | GO:0019856 | pyrimidine nucleobase biosynthetic process(GO:0019856) |
0.4 | 1.7 | GO:0000379 | tRNA-type intron splice site recognition and cleavage(GO:0000379) |
0.4 | 4.2 | GO:0000011 | vacuole inheritance(GO:0000011) |
0.4 | 8.8 | GO:0006633 | fatty acid biosynthetic process(GO:0006633) |
0.4 | 1.7 | GO:0060277 | obsolete negative regulation of transcription involved in G1 phase of mitotic cell cycle(GO:0060277) |
0.4 | 1.7 | GO:0015867 | ATP transport(GO:0015867) |
0.4 | 4.8 | GO:0007120 | axial cellular bud site selection(GO:0007120) |
0.4 | 0.8 | GO:0008612 | peptidyl-lysine modification to peptidyl-hypusine(GO:0008612) |
0.4 | 3.6 | GO:0006829 | zinc II ion transport(GO:0006829) |
0.4 | 0.4 | GO:0018344 | protein geranylgeranylation(GO:0018344) |
0.4 | 1.2 | GO:0070827 | chromatin maintenance(GO:0070827) |
0.4 | 16.6 | GO:0000910 | cytokinesis(GO:0000910) |
0.4 | 9.6 | GO:0006418 | tRNA aminoacylation for protein translation(GO:0006418) |
0.4 | 6.5 | GO:0006999 | nuclear pore organization(GO:0006999) |
0.4 | 0.4 | GO:0090502 | RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502) |
0.4 | 0.4 | GO:0034067 | protein localization to Golgi apparatus(GO:0034067) |
0.4 | 4.1 | GO:0006415 | translational termination(GO:0006415) |
0.4 | 0.7 | GO:0006658 | phosphatidylserine metabolic process(GO:0006658) |
0.4 | 1.4 | GO:0006857 | oligopeptide transport(GO:0006857) |
0.3 | 7.0 | GO:0097384 | ergosterol biosynthetic process(GO:0006696) phytosteroid biosynthetic process(GO:0016129) cellular alcohol biosynthetic process(GO:0044108) cellular lipid biosynthetic process(GO:0097384) |
0.3 | 3.7 | GO:0000083 | regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083) |
0.3 | 2.3 | GO:0007000 | nucleolus organization(GO:0007000) |
0.3 | 1.6 | GO:0007009 | plasma membrane organization(GO:0007009) |
0.3 | 1.0 | GO:0035066 | positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758) |
0.3 | 4.5 | GO:0010499 | proteasomal ubiquitin-independent protein catabolic process(GO:0010499) |
0.3 | 1.0 | GO:0042256 | mature ribosome assembly(GO:0042256) |
0.3 | 2.9 | GO:0006474 | N-terminal protein amino acid acetylation(GO:0006474) |
0.3 | 2.9 | GO:0006189 | 'de novo' IMP biosynthetic process(GO:0006189) |
0.3 | 8.0 | GO:0006487 | protein N-linked glycosylation(GO:0006487) |
0.3 | 0.6 | GO:0033262 | regulation of nuclear cell cycle DNA replication(GO:0033262) |
0.3 | 6.6 | GO:0006334 | nucleosome assembly(GO:0006334) |
0.3 | 4.0 | GO:0006409 | tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431) |
0.3 | 0.3 | GO:0018342 | protein prenylation(GO:0018342) prenylation(GO:0097354) |
0.3 | 6.7 | GO:0045454 | cell redox homeostasis(GO:0045454) |
0.3 | 0.3 | GO:0031120 | snRNA pseudouridine synthesis(GO:0031120) snRNA modification(GO:0040031) |
0.3 | 29.7 | GO:0051169 | nucleocytoplasmic transport(GO:0006913) nuclear transport(GO:0051169) |
0.3 | 1.2 | GO:0006564 | L-serine biosynthetic process(GO:0006564) |
0.3 | 0.9 | GO:0007234 | osmosensory signaling via phosphorelay pathway(GO:0007234) |
0.3 | 0.6 | GO:0031684 | heterotrimeric G-protein complex cycle(GO:0031684) |
0.3 | 1.7 | GO:0048017 | inositol lipid-mediated signaling(GO:0048017) |
0.3 | 1.1 | GO:0006720 | isoprenoid metabolic process(GO:0006720) isoprenoid biosynthetic process(GO:0008299) |
0.3 | 2.2 | GO:0015939 | pantothenate metabolic process(GO:0015939) pantothenate biosynthetic process(GO:0015940) |
0.3 | 0.5 | GO:0009226 | nucleotide-sugar biosynthetic process(GO:0009226) |
0.3 | 7.0 | GO:0006893 | Golgi to plasma membrane transport(GO:0006893) vesicle-mediated transport to the plasma membrane(GO:0098876) |
0.3 | 5.4 | GO:0042255 | ribosome assembly(GO:0042255) |
0.3 | 0.5 | GO:0009847 | spore germination(GO:0009847) |
0.3 | 0.8 | GO:0050000 | telomere localization(GO:0034397) meiotic telomere clustering(GO:0045141) chromosome localization(GO:0050000) establishment of chromosome localization(GO:0051303) chromosome localization to nuclear envelope involved in homologous chromosome segregation(GO:0090220) |
0.3 | 1.1 | GO:0007329 | positive regulation of transcription from RNA polymerase II promoter by pheromones(GO:0007329) positive regulation of transcription by pheromones(GO:0009371) |
0.3 | 2.4 | GO:0045039 | protein import into mitochondrial inner membrane(GO:0045039) |
0.3 | 8.9 | GO:0042273 | ribosomal large subunit biogenesis(GO:0042273) |
0.2 | 0.5 | GO:0034059 | response to anoxia(GO:0034059) cellular response to anoxia(GO:0071454) |
0.2 | 3.2 | GO:0072507 | cellular divalent inorganic cation homeostasis(GO:0072503) divalent inorganic cation homeostasis(GO:0072507) |
0.2 | 0.5 | GO:0019365 | nicotinate nucleotide biosynthetic process(GO:0019357) nicotinate nucleotide salvage(GO:0019358) pyridine nucleotide salvage(GO:0019365) nicotinate nucleotide metabolic process(GO:0046497) |
0.2 | 1.0 | GO:0006021 | inositol biosynthetic process(GO:0006021) |
0.2 | 0.9 | GO:0070070 | proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072) |
0.2 | 1.9 | GO:0071709 | ascospore-type prospore membrane assembly(GO:0032120) membrane biogenesis(GO:0044091) membrane assembly(GO:0071709) |
0.2 | 1.8 | GO:1903338 | regulation of cell wall organization or biogenesis(GO:1903338) |
0.2 | 2.0 | GO:0031204 | posttranslational protein targeting to membrane, translocation(GO:0031204) |
0.2 | 3.1 | GO:0006614 | cotranslational protein targeting to membrane(GO:0006613) SRP-dependent cotranslational protein targeting to membrane(GO:0006614) |
0.2 | 0.2 | GO:0034517 | ribophagy(GO:0034517) |
0.2 | 1.1 | GO:0043555 | regulation of translation in response to stress(GO:0043555) |
0.2 | 2.1 | GO:0007021 | tubulin complex assembly(GO:0007021) |
0.2 | 0.8 | GO:0030030 | cell projection organization(GO:0030030) cell projection assembly(GO:0030031) |
0.2 | 2.1 | GO:0006356 | regulation of transcription from RNA polymerase I promoter(GO:0006356) |
0.2 | 0.8 | GO:0006488 | dolichol-linked oligosaccharide biosynthetic process(GO:0006488) |
0.2 | 1.1 | GO:0000492 | box C/D snoRNP assembly(GO:0000492) |
0.2 | 0.7 | GO:0002943 | tRNA dihydrouridine synthesis(GO:0002943) |
0.2 | 0.7 | GO:0035376 | sterol import(GO:0035376) |
0.2 | 3.3 | GO:0042797 | tRNA transcription(GO:0009304) tRNA transcription from RNA polymerase III promoter(GO:0042797) |
0.2 | 23.0 | GO:0042254 | ribosome biogenesis(GO:0042254) |
0.2 | 1.4 | GO:0006012 | galactose metabolic process(GO:0006012) |
0.2 | 0.9 | GO:0060304 | regulation of phosphatidylinositol dephosphorylation(GO:0060304) endoplasmic reticulum membrane organization(GO:0090158) |
0.2 | 1.3 | GO:0046020 | regulation of transcription by pheromones(GO:0009373) negative regulation of transcription by pheromones(GO:0045996) regulation of transcription from RNA polymerase II promoter by pheromones(GO:0046019) negative regulation of transcription from RNA polymerase II promoter by pheromones(GO:0046020) |
0.2 | 1.9 | GO:0035335 | peptidyl-tyrosine dephosphorylation(GO:0035335) |
0.2 | 0.4 | GO:0032261 | purine nucleotide salvage(GO:0032261) |
0.2 | 0.5 | GO:0006283 | transcription-coupled nucleotide-excision repair(GO:0006283) |
0.2 | 1.8 | GO:0008608 | attachment of spindle microtubules to kinetochore(GO:0008608) |
0.2 | 2.3 | GO:0051568 | histone H3-K4 methylation(GO:0051568) |
0.2 | 8.4 | GO:0000747 | conjugation with cellular fusion(GO:0000747) |
0.2 | 5.8 | GO:0006413 | translational initiation(GO:0006413) |
0.2 | 0.6 | GO:0016036 | cellular response to phosphate starvation(GO:0016036) |
0.2 | 9.2 | GO:0006888 | ER to Golgi vesicle-mediated transport(GO:0006888) |
0.2 | 1.6 | GO:0010970 | establishment of localization by movement along microtubule(GO:0010970) nuclear migration along microtubule(GO:0030473) organelle transport along microtubule(GO:0072384) |
0.2 | 4.2 | GO:0006896 | Golgi to vacuole transport(GO:0006896) |
0.2 | 0.2 | GO:0006621 | protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437) |
0.1 | 0.4 | GO:0006388 | tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388) |
0.1 | 0.7 | GO:0016255 | attachment of GPI anchor to protein(GO:0016255) |
0.1 | 0.8 | GO:0019509 | L-methionine biosynthetic process from methylthioadenosine(GO:0019509) |
0.1 | 4.2 | GO:0007088 | regulation of mitotic nuclear division(GO:0007088) |
0.1 | 0.3 | GO:0097577 | intracellular sequestering of iron ion(GO:0006880) sequestering of metal ion(GO:0051238) sequestering of iron ion(GO:0097577) |
0.1 | 2.4 | GO:0006885 | regulation of pH(GO:0006885) |
0.1 | 0.5 | GO:0019748 | secondary metabolic process(GO:0019748) |
0.1 | 0.4 | GO:0006529 | asparagine biosynthetic process(GO:0006529) |
0.1 | 0.3 | GO:2000134 | negative regulation of cell cycle G1/S phase transition(GO:1902807) negative regulation of G1/S transition of mitotic cell cycle(GO:2000134) |
0.1 | 0.8 | GO:0006672 | ceramide metabolic process(GO:0006672) ceramide biosynthetic process(GO:0046513) |
0.1 | 0.9 | GO:0015677 | copper ion import(GO:0015677) |
0.1 | 1.8 | GO:0030148 | sphingolipid biosynthetic process(GO:0030148) |
0.1 | 1.0 | GO:0031163 | iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163) |
0.1 | 2.2 | GO:0045324 | late endosome to vacuole transport(GO:0045324) |
0.1 | 0.4 | GO:0006086 | acetyl-CoA biosynthetic process from pyruvate(GO:0006086) |
0.1 | 1.4 | GO:0032986 | nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986) |
0.1 | 0.5 | GO:0009051 | pentose-phosphate shunt, oxidative branch(GO:0009051) |
0.1 | 0.5 | GO:0051654 | establishment of mitochondrion localization(GO:0051654) |
0.1 | 0.8 | GO:0000105 | histidine biosynthetic process(GO:0000105) histidine metabolic process(GO:0006547) imidazole-containing compound metabolic process(GO:0052803) |
0.1 | 0.9 | GO:0051666 | actin cortical patch localization(GO:0051666) |
0.1 | 1.0 | GO:0007076 | mitotic chromosome condensation(GO:0007076) |
0.1 | 1.7 | GO:0006400 | tRNA modification(GO:0006400) |
0.1 | 0.8 | GO:0018410 | C-terminal protein amino acid modification(GO:0018410) post-translational protein modification(GO:0043687) |
0.1 | 0.4 | GO:0009306 | protein secretion(GO:0009306) |
0.1 | 0.4 | GO:0015883 | FAD transport(GO:0015883) |
0.1 | 1.0 | GO:0015918 | sterol transport(GO:0015918) |
0.1 | 0.3 | GO:0015908 | fatty acid transport(GO:0015908) |
0.1 | 1.2 | GO:0006267 | pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299) |
0.1 | 0.3 | GO:0048309 | endoplasmic reticulum inheritance(GO:0048309) |
0.1 | 0.9 | GO:0070816 | phosphorylation of RNA polymerase II C-terminal domain(GO:0070816) |
0.1 | 0.2 | GO:0035268 | protein mannosylation(GO:0035268) protein O-linked mannosylation(GO:0035269) mannosylation(GO:0097502) |
0.1 | 0.3 | GO:0043007 | maintenance of rDNA(GO:0043007) |
0.1 | 0.2 | GO:0036498 | mRNA splicing via endonucleolytic cleavage and ligation involved in unfolded protein response(GO:0030969) IRE1-mediated unfolded protein response(GO:0036498) mRNA splicing, via endonucleolytic cleavage and ligation(GO:0070054) |
0.1 | 2.7 | GO:0046474 | glycerophospholipid biosynthetic process(GO:0046474) |
0.1 | 0.2 | GO:0030835 | regulation of actin filament depolymerization(GO:0030834) negative regulation of actin filament depolymerization(GO:0030835) barbed-end actin filament capping(GO:0051016) actin filament capping(GO:0051693) |
0.1 | 0.5 | GO:0034551 | respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) |
0.1 | 0.8 | GO:0006273 | lagging strand elongation(GO:0006273) |
0.1 | 0.3 | GO:0070898 | transcription initiation from RNA polymerase III promoter(GO:0006384) RNA polymerase III transcriptional preinitiation complex assembly(GO:0070898) |
0.1 | 0.5 | GO:0043162 | ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162) |
0.1 | 0.2 | GO:0055075 | cellular potassium ion homeostasis(GO:0030007) potassium ion homeostasis(GO:0055075) |
0.1 | 4.8 | GO:0032543 | mitochondrial translation(GO:0032543) |
0.1 | 0.5 | GO:0009086 | methionine biosynthetic process(GO:0009086) |
0.1 | 0.9 | GO:0030472 | mitotic spindle organization in nucleus(GO:0030472) |
0.1 | 0.1 | GO:0051176 | regulation of vitamin metabolic process(GO:0030656) positive regulation of vitamin metabolic process(GO:0046136) positive regulation of sulfur metabolic process(GO:0051176) regulation of thiamine biosynthetic process(GO:0070623) positive regulation of thiamine biosynthetic process(GO:0090180) |
0.1 | 0.3 | GO:0006627 | protein processing involved in protein targeting to mitochondrion(GO:0006627) |
0.0 | 0.4 | GO:0006891 | intra-Golgi vesicle-mediated transport(GO:0006891) |
0.0 | 0.2 | GO:0051495 | positive regulation of cytoskeleton organization(GO:0051495) |
0.0 | 0.1 | GO:0006311 | meiotic gene conversion(GO:0006311) |
0.0 | 0.1 | GO:0031087 | deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087) |
0.0 | 0.2 | GO:0044088 | regulation of vacuole fusion, non-autophagic(GO:0032889) regulation of vacuole organization(GO:0044088) |
0.0 | 0.5 | GO:0007004 | RNA-dependent DNA biosynthetic process(GO:0006278) telomere maintenance via telomerase(GO:0007004) |
0.0 | 0.5 | GO:0043413 | protein glycosylation(GO:0006486) macromolecule glycosylation(GO:0043413) |
0.0 | 0.2 | GO:0030847 | termination of RNA polymerase II transcription, exosome-dependent(GO:0030847) |
0.0 | 0.1 | GO:0031047 | gene silencing involved in chronological cell aging(GO:0010978) gene silencing by RNA(GO:0031047) |
0.0 | 0.1 | GO:0006816 | calcium ion transport(GO:0006816) |
0.0 | 0.1 | GO:0007323 | peptide pheromone maturation(GO:0007323) |
0.0 | 0.0 | GO:0006892 | post-Golgi vesicle-mediated transport(GO:0006892) |
0.0 | 0.1 | GO:0001111 | promoter clearance during DNA-templated transcription(GO:0001109) promoter clearance from RNA polymerase II promoter(GO:0001111) |
0.0 | 0.2 | GO:0016482 | cytosolic transport(GO:0016482) |
0.0 | 0.1 | GO:0006089 | lactate metabolic process(GO:0006089) |
0.0 | 0.1 | GO:0032786 | regulation of DNA-templated transcription, elongation(GO:0032784) positive regulation of DNA-templated transcription, elongation(GO:0032786) positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968) regulation of transcription elongation from RNA polymerase II promoter(GO:0034243) |
0.0 | 0.1 | GO:0006370 | 7-methylguanosine mRNA capping(GO:0006370) |
0.0 | 0.0 | GO:0072530 | cytosine transport(GO:0015856) purine-containing compound transmembrane transport(GO:0072530) |
0.0 | 0.1 | GO:0042138 | meiotic DNA double-strand break formation(GO:0042138) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
14.2 | 42.5 | GO:0030428 | cell septum(GO:0030428) |
11.9 | 35.7 | GO:0032299 | ribonuclease H2 complex(GO:0032299) |
3.2 | 9.6 | GO:0070545 | PeBoW complex(GO:0070545) |
3.1 | 9.3 | GO:0005854 | nascent polypeptide-associated complex(GO:0005854) |
1.9 | 5.6 | GO:0045298 | polar microtubule(GO:0005827) tubulin complex(GO:0045298) |
1.8 | 7.3 | GO:0005946 | alpha,alpha-trehalose-phosphate synthase complex (UDP-forming)(GO:0005946) |
1.8 | 5.4 | GO:0043529 | GET complex(GO:0043529) |
1.7 | 101.3 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
1.6 | 1.6 | GO:0005793 | endoplasmic reticulum-Golgi intermediate compartment(GO:0005793) |
1.5 | 127.3 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
1.4 | 7.2 | GO:0000408 | EKC/KEOPS complex(GO:0000408) |
1.3 | 10.4 | GO:0030126 | COPI vesicle coat(GO:0030126) |
1.2 | 86.8 | GO:0005576 | extracellular region(GO:0005576) |
1.1 | 5.6 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
1.1 | 3.3 | GO:0042719 | mitochondrial intermembrane space protein transporter complex(GO:0042719) |
1.1 | 8.7 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
1.0 | 7.8 | GO:0000144 | cellular bud neck septin ring(GO:0000144) |
1.0 | 5.8 | GO:0043527 | tRNA methyltransferase complex(GO:0043527) |
1.0 | 2.9 | GO:0031417 | NatC complex(GO:0031417) |
1.0 | 2.9 | GO:0005850 | eukaryotic translation initiation factor 2 complex(GO:0005850) |
0.9 | 6.2 | GO:0032432 | actin filament bundle(GO:0032432) |
0.9 | 2.6 | GO:0071261 | Ssh1 translocon complex(GO:0071261) |
0.9 | 1.7 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
0.8 | 11.3 | GO:0005736 | DNA-directed RNA polymerase I complex(GO:0005736) |
0.8 | 3.2 | GO:0030123 | AP-3 adaptor complex(GO:0030123) |
0.7 | 5.6 | GO:0031933 | nuclear heterochromatin(GO:0005720) nuclear telomeric heterochromatin(GO:0005724) telomeric heterochromatin(GO:0031933) |
0.7 | 2.1 | GO:0009331 | glycerol-3-phosphate dehydrogenase complex(GO:0009331) |
0.7 | 11.7 | GO:0022626 | cytosolic ribosome(GO:0022626) |
0.6 | 8.9 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
0.6 | 5.1 | GO:0035097 | histone methyltransferase complex(GO:0035097) Set1C/COMPASS complex(GO:0048188) |
0.6 | 20.7 | GO:0030134 | ER to Golgi transport vesicle(GO:0030134) |
0.5 | 3.0 | GO:0005940 | septin ring(GO:0005940) |
0.5 | 2.9 | GO:0035339 | serine C-palmitoyltransferase complex(GO:0017059) SPOTS complex(GO:0035339) |
0.5 | 4.3 | GO:0030681 | nucleolar ribonuclease P complex(GO:0005655) multimeric ribonuclease P complex(GO:0030681) |
0.5 | 6.7 | GO:0000786 | nucleosome(GO:0000786) |
0.5 | 6.4 | GO:0000176 | nuclear exosome (RNase complex)(GO:0000176) |
0.5 | 2.7 | GO:0034456 | UTP-C complex(GO:0034456) |
0.5 | 3.6 | GO:0030008 | TRAPP complex(GO:0030008) |
0.4 | 1.8 | GO:0033254 | vacuolar transporter chaperone complex(GO:0033254) |
0.4 | 3.5 | GO:0005885 | Arp2/3 protein complex(GO:0005885) |
0.4 | 6.0 | GO:0034399 | nuclear periphery(GO:0034399) |
0.4 | 3.4 | GO:0005688 | U6 snRNP(GO:0005688) |
0.4 | 75.3 | GO:0005933 | cellular bud(GO:0005933) |
0.4 | 1.7 | GO:0000214 | tRNA-intron endonuclease complex(GO:0000214) |
0.4 | 2.1 | GO:0030689 | Noc complex(GO:0030689) |
0.4 | 1.2 | GO:0031315 | extrinsic component of mitochondrial outer membrane(GO:0031315) |
0.4 | 15.0 | GO:0005811 | lipid particle(GO:0005811) |
0.4 | 1.5 | GO:0044611 | nuclear pore inner ring(GO:0044611) |
0.4 | 2.3 | GO:0034045 | pre-autophagosomal structure membrane(GO:0034045) |
0.4 | 1.5 | GO:0031428 | box C/D snoRNP complex(GO:0031428) |
0.4 | 1.1 | GO:0005845 | mRNA cap binding complex(GO:0005845) |
0.4 | 2.6 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
0.3 | 3.1 | GO:0000137 | Golgi cis cisterna(GO:0000137) |
0.3 | 2.4 | GO:0005697 | telomerase holoenzyme complex(GO:0005697) |
0.3 | 2.4 | GO:0019773 | proteasome core complex, alpha-subunit complex(GO:0019773) |
0.3 | 1.0 | GO:0005880 | nuclear microtubule(GO:0005880) |
0.3 | 1.0 | GO:0032301 | MutSalpha complex(GO:0032301) |
0.3 | 1.3 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
0.3 | 8.7 | GO:0005844 | polysome(GO:0005844) |
0.3 | 2.8 | GO:0030137 | COPI-coated vesicle(GO:0030137) |
0.3 | 2.1 | GO:0019774 | proteasome core complex, beta-subunit complex(GO:0019774) |
0.3 | 4.0 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
0.3 | 2.1 | GO:0000346 | transcription export complex(GO:0000346) |
0.3 | 1.2 | GO:0034990 | mitotic cohesin complex(GO:0030892) nuclear mitotic cohesin complex(GO:0034990) |
0.3 | 2.1 | GO:0072686 | mitotic spindle(GO:0072686) |
0.3 | 0.9 | GO:0097344 | Rix1 complex(GO:0097344) |
0.3 | 1.4 | GO:0005851 | eukaryotic translation initiation factor 2B complex(GO:0005851) |
0.3 | 2.3 | GO:0005791 | rough endoplasmic reticulum(GO:0005791) rough endoplasmic reticulum membrane(GO:0030867) |
0.3 | 34.0 | GO:0005840 | ribosome(GO:0005840) |
0.3 | 1.3 | GO:0000500 | RNA polymerase I upstream activating factor complex(GO:0000500) |
0.3 | 0.8 | GO:0000120 | RNA polymerase I transcription factor complex(GO:0000120) RNA polymerase I core factor complex(GO:0070860) |
0.3 | 0.8 | GO:0043541 | UDP-N-acetylglucosamine transferase complex(GO:0043541) |
0.2 | 1.5 | GO:0042555 | MCM complex(GO:0042555) |
0.2 | 0.7 | GO:0033186 | CAF-1 complex(GO:0033186) |
0.2 | 0.9 | GO:0031518 | CBF3 complex(GO:0031518) |
0.2 | 4.9 | GO:0005887 | integral component of plasma membrane(GO:0005887) |
0.2 | 0.7 | GO:0097255 | R2TP complex(GO:0097255) |
0.2 | 1.3 | GO:0042597 | periplasmic space(GO:0042597) |
0.2 | 1.1 | GO:0016272 | prefoldin complex(GO:0016272) |
0.2 | 0.8 | GO:0031502 | dolichyl-phosphate-mannose-protein mannosyltransferase complex(GO:0031502) |
0.2 | 1.4 | GO:0034455 | t-UTP complex(GO:0034455) |
0.2 | 1.0 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
0.2 | 30.7 | GO:0005730 | nucleolus(GO:0005730) |
0.2 | 1.0 | GO:0044615 | nuclear pore nuclear basket(GO:0044615) |
0.2 | 1.3 | GO:0005665 | DNA-directed RNA polymerase II, core complex(GO:0005665) |
0.2 | 0.4 | GO:0005796 | Golgi lumen(GO:0005796) |
0.2 | 0.8 | GO:0030121 | AP-1 adaptor complex(GO:0030121) |
0.2 | 0.6 | GO:0034044 | exomer complex(GO:0034044) |
0.1 | 0.6 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
0.1 | 0.7 | GO:0042765 | GPI-anchor transamidase complex(GO:0042765) |
0.1 | 0.6 | GO:0005797 | Golgi medial cisterna(GO:0005797) |
0.1 | 2.1 | GO:0000784 | nuclear chromosome, telomeric region(GO:0000784) |
0.1 | 1.4 | GO:0008541 | proteasome regulatory particle, lid subcomplex(GO:0008541) |
0.1 | 0.9 | GO:0000439 | core TFIIH complex(GO:0000439) |
0.1 | 0.4 | GO:0000814 | ESCRT II complex(GO:0000814) |
0.1 | 0.5 | GO:0000220 | vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220) proton-transporting V-type ATPase, V0 domain(GO:0033179) |
0.1 | 3.9 | GO:0030176 | integral component of endoplasmic reticulum membrane(GO:0030176) |
0.1 | 0.8 | GO:0033180 | vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221) proton-transporting V-type ATPase, V1 domain(GO:0033180) |
0.1 | 0.4 | GO:0005955 | calcineurin complex(GO:0005955) |
0.1 | 0.7 | GO:0033588 | Elongator holoenzyme complex(GO:0033588) |
0.1 | 2.1 | GO:0016586 | RSC complex(GO:0016586) |
0.1 | 0.4 | GO:0031597 | cytosolic proteasome complex(GO:0031597) proteasome storage granule(GO:0034515) |
0.1 | 0.4 | GO:0045254 | mitochondrial pyruvate dehydrogenase complex(GO:0005967) pyruvate dehydrogenase complex(GO:0045254) |
0.1 | 0.7 | GO:0031227 | intrinsic component of endoplasmic reticulum membrane(GO:0031227) |
0.1 | 4.9 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
0.1 | 1.7 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
0.1 | 11.6 | GO:0005759 | mitochondrial matrix(GO:0005759) |
0.1 | 0.6 | GO:0035327 | transcriptionally active chromatin(GO:0035327) |
0.1 | 0.1 | GO:0033553 | rDNA heterochromatin(GO:0033553) |
0.1 | 1.1 | GO:0019897 | extrinsic component of plasma membrane(GO:0019897) |
0.1 | 0.2 | GO:0070762 | nuclear pore transmembrane ring(GO:0070762) |
0.1 | 0.3 | GO:0031985 | Golgi cisterna(GO:0031985) |
0.1 | 0.5 | GO:0008023 | transcription elongation factor complex(GO:0008023) |
0.1 | 0.1 | GO:0005640 | nuclear outer membrane(GO:0005640) |
0.1 | 0.5 | GO:0044613 | nuclear pore central transport channel(GO:0044613) |
0.1 | 0.4 | GO:0031080 | nuclear pore outer ring(GO:0031080) |
0.1 | 0.1 | GO:0005801 | cis-Golgi network(GO:0005801) |
0.1 | 0.7 | GO:0005669 | transcription factor TFIID complex(GO:0005669) |
0.1 | 12.5 | GO:0005783 | endoplasmic reticulum(GO:0005783) |
0.0 | 0.3 | GO:0031228 | integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228) |
0.0 | 0.2 | GO:0005786 | signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500) |
0.0 | 0.5 | GO:0098857 | membrane raft(GO:0045121) membrane microdomain(GO:0098857) |
0.0 | 0.5 | GO:0031231 | integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231) |
0.0 | 0.2 | GO:0000815 | ESCRT III complex(GO:0000815) |
0.0 | 3.8 | GO:0005768 | endosome(GO:0005768) |
0.0 | 0.1 | GO:0005662 | DNA replication factor A complex(GO:0005662) |
0.0 | 0.1 | GO:0005674 | transcription factor TFIIF complex(GO:0005674) |
0.0 | 0.1 | GO:0032116 | SMC loading complex(GO:0032116) |
0.0 | 0.2 | GO:0017119 | Golgi transport complex(GO:0017119) |
0.0 | 0.3 | GO:0000243 | commitment complex(GO:0000243) |
0.0 | 0.1 | GO:0070823 | HDA1 complex(GO:0070823) |
0.0 | 0.1 | GO:0097196 | Shu complex(GO:0097196) |
0.0 | 0.1 | GO:0034708 | methyltransferase complex(GO:0034708) |
0.0 | 0.4 | GO:0005874 | microtubule(GO:0005874) |
0.0 | 0.1 | GO:0030015 | CCR4-NOT core complex(GO:0030015) |
0.0 | 0.1 | GO:0005663 | DNA replication factor C complex(GO:0005663) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
10.1 | 30.2 | GO:0070568 | guanylyltransferase activity(GO:0070568) |
8.9 | 35.7 | GO:0004523 | RNA-DNA hybrid ribonuclease activity(GO:0004523) |
7.5 | 29.9 | GO:0042973 | glucan endo-1,3-beta-D-glucosidase activity(GO:0042973) |
5.6 | 33.3 | GO:0016846 | carbon-sulfur lyase activity(GO:0016846) |
4.7 | 14.2 | GO:0004826 | phenylalanine-tRNA ligase activity(GO:0004826) |
4.3 | 17.0 | GO:0016841 | ammonia-lyase activity(GO:0016841) |
4.2 | 12.5 | GO:0003938 | IMP dehydrogenase activity(GO:0003938) |
3.1 | 3.1 | GO:0004805 | trehalose-phosphatase activity(GO:0004805) |
2.9 | 52.0 | GO:0015926 | glucosidase activity(GO:0015926) |
2.7 | 13.3 | GO:0036002 | pre-mRNA binding(GO:0036002) |
2.6 | 7.9 | GO:0003841 | 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) |
2.6 | 15.6 | GO:0004022 | alcohol dehydrogenase (NAD) activity(GO:0004022) |
2.4 | 7.2 | GO:0004365 | glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891) |
2.4 | 7.1 | GO:0004619 | phosphoglycerate mutase activity(GO:0004619) |
2.2 | 38.7 | GO:0004553 | hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553) |
2.1 | 12.8 | GO:0070300 | phosphatidic acid binding(GO:0070300) |
2.1 | 8.3 | GO:0016634 | oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634) |
2.0 | 12.1 | GO:0003906 | DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906) |
1.8 | 7.1 | GO:0005527 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
1.6 | 4.8 | GO:0019003 | GDP binding(GO:0019003) |
1.4 | 4.2 | GO:0003825 | alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity(GO:0003825) |
1.4 | 5.5 | GO:0004467 | long-chain fatty acid-CoA ligase activity(GO:0004467) |
1.4 | 9.5 | GO:0015665 | alcohol transmembrane transporter activity(GO:0015665) |
1.3 | 1.3 | GO:0031957 | very long-chain fatty acid-CoA ligase activity(GO:0031957) |
1.3 | 3.9 | GO:0009922 | fatty acid elongase activity(GO:0009922) |
1.2 | 3.7 | GO:0004809 | tRNA (guanine-N2-)-methyltransferase activity(GO:0004809) |
1.2 | 4.8 | GO:0000297 | spermine transmembrane transporter activity(GO:0000297) |
1.2 | 3.6 | GO:0016717 | oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717) |
1.2 | 7.1 | GO:0016408 | C-acyltransferase activity(GO:0016408) |
1.2 | 54.5 | GO:0019843 | rRNA binding(GO:0019843) |
1.2 | 11.8 | GO:0001133 | RNA polymerase II transcription factor activity, sequence-specific transcription regulatory region DNA binding(GO:0001133) |
1.2 | 5.8 | GO:0004749 | ribose phosphate diphosphokinase activity(GO:0004749) |
1.1 | 6.8 | GO:0015198 | oligopeptide transporter activity(GO:0015198) |
1.1 | 5.7 | GO:0042124 | glucanosyltransferase activity(GO:0042123) 1,3-beta-glucanosyltransferase activity(GO:0042124) |
1.1 | 5.6 | GO:0008536 | Ran GTPase binding(GO:0008536) |
1.1 | 8.7 | GO:0004576 | oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
1.1 | 15.3 | GO:0015578 | fructose transmembrane transporter activity(GO:0005353) mannose transmembrane transporter activity(GO:0015578) |
1.1 | 4.2 | GO:0004622 | lysophospholipase activity(GO:0004622) |
1.0 | 4.0 | GO:0016661 | oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661) |
1.0 | 4.9 | GO:0004707 | MAP kinase activity(GO:0004707) |
1.0 | 2.9 | GO:0016838 | carbon-oxygen lyase activity, acting on phosphates(GO:0016838) |
0.9 | 169.7 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
0.9 | 6.5 | GO:0016742 | hydroxymethyl-, formyl- and related transferase activity(GO:0016742) |
0.9 | 5.6 | GO:0016709 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709) |
0.9 | 2.7 | GO:0015114 | phosphate ion transmembrane transporter activity(GO:0015114) |
0.9 | 3.7 | GO:0019206 | nucleoside kinase activity(GO:0019206) |
0.9 | 7.9 | GO:0005545 | 1-phosphatidylinositol binding(GO:0005545) |
0.8 | 2.5 | GO:0019203 | carbohydrate phosphatase activity(GO:0019203) sugar-phosphatase activity(GO:0050308) |
0.8 | 3.4 | GO:0016832 | aldehyde-lyase activity(GO:0016832) |
0.8 | 2.5 | GO:0051219 | phosphoprotein binding(GO:0051219) |
0.8 | 2.4 | GO:0031370 | eukaryotic initiation factor 4G binding(GO:0031370) |
0.8 | 11.3 | GO:0001054 | RNA polymerase I activity(GO:0001054) |
0.8 | 2.4 | GO:0019202 | amino acid kinase activity(GO:0019202) |
0.7 | 0.7 | GO:1904680 | peptide-transporting ATPase activity(GO:0015440) peptide transmembrane transporter activity(GO:1904680) |
0.7 | 3.5 | GO:0005338 | nucleotide-sugar transmembrane transporter activity(GO:0005338) |
0.7 | 3.5 | GO:0005496 | steroid binding(GO:0005496) sterol binding(GO:0032934) |
0.7 | 6.6 | GO:0016668 | oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668) |
0.6 | 5.1 | GO:0042800 | histone methyltransferase activity (H3-K4 specific)(GO:0042800) |
0.6 | 16.3 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
0.6 | 1.8 | GO:0015088 | copper uptake transmembrane transporter activity(GO:0015088) |
0.6 | 6.7 | GO:0043495 | protein anchor(GO:0043495) |
0.6 | 4.8 | GO:0016861 | intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861) |
0.6 | 1.8 | GO:0003873 | 6-phosphofructo-2-kinase activity(GO:0003873) |
0.6 | 1.8 | GO:0016504 | peptidase activator activity(GO:0016504) |
0.6 | 3.4 | GO:0001132 | RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132) |
0.6 | 2.2 | GO:0001046 | core promoter sequence-specific DNA binding(GO:0001046) |
0.5 | 2.7 | GO:0000099 | sulfur amino acid transmembrane transporter activity(GO:0000099) |
0.5 | 2.7 | GO:0043141 | 5'-3' DNA helicase activity(GO:0043139) ATP-dependent 5'-3' DNA helicase activity(GO:0043141) |
0.5 | 3.2 | GO:0047429 | nucleoside-triphosphate diphosphatase activity(GO:0047429) |
0.5 | 3.7 | GO:0003725 | double-stranded RNA binding(GO:0003725) |
0.5 | 1.5 | GO:0016972 | oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670) thiol oxidase activity(GO:0016972) |
0.5 | 9.4 | GO:0042162 | telomeric DNA binding(GO:0042162) |
0.5 | 0.5 | GO:0016778 | diphosphotransferase activity(GO:0016778) |
0.5 | 2.0 | GO:0004602 | glutathione peroxidase activity(GO:0004602) |
0.5 | 3.9 | GO:0031490 | chromatin DNA binding(GO:0031490) |
0.5 | 1.9 | GO:0004614 | phosphoglucomutase activity(GO:0004614) |
0.5 | 5.9 | GO:0015035 | protein disulfide oxidoreductase activity(GO:0015035) |
0.4 | 5.8 | GO:0051015 | actin filament binding(GO:0051015) |
0.4 | 1.7 | GO:0019901 | protein kinase binding(GO:0019901) |
0.4 | 1.3 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
0.4 | 4.3 | GO:0000171 | ribonuclease MRP activity(GO:0000171) |
0.4 | 1.7 | GO:0000213 | tRNA-intron endonuclease activity(GO:0000213) |
0.4 | 1.2 | GO:0004488 | methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488) |
0.4 | 0.8 | GO:0030976 | thiamine pyrophosphate binding(GO:0030976) |
0.4 | 1.2 | GO:0050291 | sphingosine N-acyltransferase activity(GO:0050291) |
0.4 | 1.9 | GO:0030145 | manganese ion binding(GO:0030145) |
0.4 | 1.1 | GO:0004376 | glycolipid mannosyltransferase activity(GO:0004376) |
0.4 | 10.8 | GO:0004722 | protein serine/threonine phosphatase activity(GO:0004722) |
0.4 | 2.9 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
0.4 | 1.8 | GO:0016423 | tRNA (guanine) methyltransferase activity(GO:0016423) |
0.4 | 6.4 | GO:0004520 | endodeoxyribonuclease activity(GO:0004520) |
0.4 | 2.5 | GO:0072509 | divalent inorganic cation transmembrane transporter activity(GO:0072509) |
0.3 | 2.7 | GO:0005216 | ion channel activity(GO:0005216) |
0.3 | 1.0 | GO:0042910 | xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910) |
0.3 | 1.7 | GO:0019201 | nucleotide kinase activity(GO:0019201) |
0.3 | 6.0 | GO:0043022 | ribosome binding(GO:0043022) |
0.3 | 1.0 | GO:0030060 | L-malate dehydrogenase activity(GO:0030060) |
0.3 | 1.3 | GO:0001168 | transcription factor activity, RNA polymerase I upstream control element sequence-specific binding(GO:0001168) |
0.3 | 0.7 | GO:0003785 | actin monomer binding(GO:0003785) |
0.3 | 1.6 | GO:0070403 | NAD+ binding(GO:0070403) |
0.3 | 1.6 | GO:0000026 | alpha-1,2-mannosyltransferase activity(GO:0000026) |
0.3 | 4.5 | GO:0004659 | prenyltransferase activity(GO:0004659) |
0.3 | 2.9 | GO:0004596 | peptide alpha-N-acetyltransferase activity(GO:0004596) |
0.3 | 0.6 | GO:0099516 | ion antiporter activity(GO:0099516) |
0.3 | 2.2 | GO:0000009 | alpha-1,6-mannosyltransferase activity(GO:0000009) |
0.3 | 2.5 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
0.3 | 1.3 | GO:0009378 | four-way junction helicase activity(GO:0009378) |
0.3 | 8.4 | GO:0003743 | translation initiation factor activity(GO:0003743) |
0.3 | 3.1 | GO:0004177 | aminopeptidase activity(GO:0004177) |
0.3 | 0.9 | GO:0005519 | cytoskeletal regulatory protein binding(GO:0005519) |
0.3 | 3.7 | GO:0016884 | carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884) |
0.3 | 2.1 | GO:0015450 | P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450) |
0.3 | 3.3 | GO:0015079 | potassium ion transmembrane transporter activity(GO:0015079) |
0.3 | 18.2 | GO:0003924 | GTPase activity(GO:0003924) |
0.3 | 4.1 | GO:0001671 | ATPase activator activity(GO:0001671) |
0.3 | 2.0 | GO:0031386 | protein tag(GO:0031386) |
0.3 | 2.3 | GO:0080025 | phosphatidylinositol-3,5-bisphosphate binding(GO:0080025) |
0.3 | 4.7 | GO:0016763 | transferase activity, transferring pentosyl groups(GO:0016763) |
0.3 | 8.6 | GO:0016876 | aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876) |
0.3 | 0.8 | GO:0004930 | G-protein coupled receptor activity(GO:0004930) |
0.3 | 2.4 | GO:0008175 | tRNA methyltransferase activity(GO:0008175) |
0.3 | 1.1 | GO:0016886 | ligase activity, forming phosphoric ester bonds(GO:0016886) |
0.3 | 1.6 | GO:0004169 | dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169) |
0.3 | 5.9 | GO:0016836 | hydro-lyase activity(GO:0016836) |
0.3 | 0.8 | GO:0004497 | monooxygenase activity(GO:0004497) |
0.2 | 0.5 | GO:0031683 | G-protein beta/gamma-subunit complex binding(GO:0031683) |
0.2 | 6.0 | GO:0003779 | actin binding(GO:0003779) |
0.2 | 1.2 | GO:0017048 | Rho GTPase binding(GO:0017048) |
0.2 | 4.4 | GO:0016765 | transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765) |
0.2 | 1.2 | GO:0000033 | alpha-1,3-mannosyltransferase activity(GO:0000033) |
0.2 | 0.5 | GO:0008238 | exopeptidase activity(GO:0008238) |
0.2 | 0.7 | GO:0070273 | phosphatidylinositol-4-phosphate binding(GO:0070273) |
0.2 | 2.6 | GO:0042803 | protein homodimerization activity(GO:0042803) |
0.2 | 0.9 | GO:0005092 | GDP-dissociation inhibitor activity(GO:0005092) |
0.2 | 2.8 | GO:0070003 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
0.2 | 3.1 | GO:0050661 | NADP binding(GO:0050661) |
0.2 | 7.3 | GO:0008092 | cytoskeletal protein binding(GO:0008092) |
0.2 | 0.9 | GO:0003746 | translation elongation factor activity(GO:0003746) |
0.2 | 0.4 | GO:0015606 | spermidine transmembrane transporter activity(GO:0015606) |
0.2 | 0.8 | GO:0008172 | S-methyltransferase activity(GO:0008172) |
0.2 | 0.8 | GO:0001055 | RNA polymerase II activity(GO:0001055) |
0.2 | 1.6 | GO:0005516 | calmodulin binding(GO:0005516) |
0.2 | 1.0 | GO:0003993 | acid phosphatase activity(GO:0003993) |
0.2 | 0.7 | GO:0017150 | tRNA dihydrouridine synthase activity(GO:0017150) |
0.2 | 5.4 | GO:0046982 | protein heterodimerization activity(GO:0046982) |
0.2 | 0.5 | GO:0003968 | RNA-directed RNA polymerase activity(GO:0003968) |
0.2 | 3.2 | GO:0008301 | DNA binding, bending(GO:0008301) |
0.2 | 1.4 | GO:0030295 | protein kinase activator activity(GO:0030295) |
0.2 | 0.5 | GO:0016799 | hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799) |
0.2 | 0.3 | GO:0016671 | oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671) |
0.1 | 0.7 | GO:0015173 | aromatic amino acid transmembrane transporter activity(GO:0015173) |
0.1 | 3.5 | GO:0017056 | structural constituent of nuclear pore(GO:0017056) |
0.1 | 0.7 | GO:0034318 | alcohol O-acetyltransferase activity(GO:0004026) alcohol O-acyltransferase activity(GO:0034318) |
0.1 | 0.7 | GO:0003923 | GPI-anchor transamidase activity(GO:0003923) |
0.1 | 1.7 | GO:0016859 | peptidyl-prolyl cis-trans isomerase activity(GO:0003755) cis-trans isomerase activity(GO:0016859) |
0.1 | 2.0 | GO:0015605 | organophosphate ester transmembrane transporter activity(GO:0015605) |
0.1 | 7.0 | GO:0008565 | protein transporter activity(GO:0008565) |
0.1 | 1.8 | GO:0003714 | transcription corepressor activity(GO:0003714) |
0.1 | 0.4 | GO:0016872 | intramolecular lyase activity(GO:0016872) |
0.1 | 0.4 | GO:0008251 | adenosine deaminase activity(GO:0004000) tRNA-specific adenosine deaminase activity(GO:0008251) |
0.1 | 0.4 | GO:0008242 | metalloexopeptidase activity(GO:0008235) omega peptidase activity(GO:0008242) |
0.1 | 0.6 | GO:0017169 | CDP-alcohol phosphatidyltransferase activity(GO:0017169) |
0.1 | 0.2 | GO:0001082 | transcription factor activity, RNA polymerase I transcription factor binding(GO:0001082) |
0.1 | 0.3 | GO:0000339 | RNA cap binding(GO:0000339) |
0.1 | 2.9 | GO:0030674 | protein binding, bridging(GO:0030674) |
0.1 | 1.4 | GO:0016866 | intramolecular transferase activity(GO:0016866) |
0.1 | 2.7 | GO:0004004 | ATP-dependent RNA helicase activity(GO:0004004) |
0.1 | 0.8 | GO:0016780 | phosphotransferase activity, for other substituted phosphate groups(GO:0016780) |
0.1 | 0.4 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
0.1 | 0.6 | GO:0000182 | rDNA binding(GO:0000182) |
0.1 | 1.7 | GO:0016831 | carboxy-lyase activity(GO:0016831) |
0.1 | 1.2 | GO:0016853 | isomerase activity(GO:0016853) |
0.1 | 0.6 | GO:0000991 | transcription factor activity, core RNA polymerase II binding(GO:0000991) |
0.1 | 0.8 | GO:0001075 | transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075) |
0.1 | 0.3 | GO:0005487 | nucleocytoplasmic transporter activity(GO:0005487) |
0.1 | 0.7 | GO:0000049 | tRNA binding(GO:0000049) |
0.1 | 0.3 | GO:0016417 | S-acyltransferase activity(GO:0016417) |
0.1 | 0.9 | GO:0051087 | chaperone binding(GO:0051087) |
0.1 | 1.2 | GO:0000030 | mannosyltransferase activity(GO:0000030) |
0.1 | 0.7 | GO:0043175 | RNA polymerase core enzyme binding(GO:0043175) RNA polymerase binding(GO:0070063) |
0.1 | 0.5 | GO:0019904 | protein domain specific binding(GO:0019904) |
0.1 | 0.8 | GO:0030515 | snoRNA binding(GO:0030515) |
0.1 | 1.8 | GO:0043130 | ubiquitin binding(GO:0043130) |
0.0 | 0.2 | GO:0080130 | L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130) |
0.0 | 0.4 | GO:0005381 | iron ion transmembrane transporter activity(GO:0005381) |
0.0 | 0.5 | GO:0003774 | motor activity(GO:0003774) |
0.0 | 0.1 | GO:0060090 | binding, bridging(GO:0060090) |
0.0 | 0.2 | GO:0008525 | phosphatidylcholine transporter activity(GO:0008525) phosphatidylinositol transporter activity(GO:0008526) |
0.0 | 0.6 | GO:0005048 | signal sequence binding(GO:0005048) |
0.0 | 0.2 | GO:0030276 | clathrin binding(GO:0030276) |
0.0 | 0.6 | GO:0005525 | GTP binding(GO:0005525) guanyl nucleotide binding(GO:0019001) guanyl ribonucleotide binding(GO:0032561) |
0.0 | 0.2 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
0.0 | 0.6 | GO:0008237 | metallopeptidase activity(GO:0008237) |
0.0 | 0.1 | GO:0004312 | fatty acid synthase activity(GO:0004312) |
0.0 | 0.2 | GO:0017069 | snRNA binding(GO:0017069) |
0.0 | 0.0 | GO:0008601 | protein phosphatase type 2A regulator activity(GO:0008601) |
0.0 | 0.1 | GO:0016655 | oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor(GO:0016655) |
0.0 | 0.8 | GO:0016791 | phosphatase activity(GO:0016791) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
3.5 | 10.6 | PID SHP2 PATHWAY | SHP2 signaling |
2.5 | 2.5 | PID PDGFRB PATHWAY | PDGFR-beta signaling pathway |
1.8 | 5.4 | PID UPA UPAR PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
0.9 | 0.9 | PID VEGFR1 2 PATHWAY | Signaling events mediated by VEGFR1 and VEGFR2 |
0.7 | 2.0 | PID HIF1 TFPATHWAY | HIF-1-alpha transcription factor network |
0.6 | 1.2 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
0.6 | 1.7 | PID P38 ALPHA BETA DOWNSTREAM PATHWAY | Signaling mediated by p38-alpha and p38-beta |
0.4 | 0.4 | PID VEGFR1 PATHWAY | VEGFR1 specific signals |
0.4 | 1.3 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
0.4 | 1.2 | PID FGF PATHWAY | FGF signaling pathway |
0.4 | 1.8 | PID PLK1 PATHWAY | PLK1 signaling events |
0.2 | 0.2 | PID ANGIOPOIETIN RECEPTOR PATHWAY | Angiopoietin receptor Tie2-mediated signaling |
0.2 | 0.5 | PID FOXO PATHWAY | FoxO family signaling |
0.1 | 0.3 | PID INTEGRIN A4B1 PATHWAY | Alpha4 beta1 integrin signaling events |
0.1 | 0.2 | SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES | Genes related to the insulin receptor pathway |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
3.5 | 10.6 | REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR | Genes involved in Downstream signaling of activated FGFR |
2.0 | 47.3 | REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION | Genes involved in 3' -UTR-mediated translational regulation |
1.6 | 4.9 | REACTOME CITRIC ACID CYCLE TCA CYCLE | Genes involved in Citric acid cycle (TCA cycle) |
1.4 | 5.4 | REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS | Genes involved in Class A/1 (Rhodopsin-like receptors) |
0.9 | 0.9 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
0.9 | 0.9 | REACTOME INTERFERON SIGNALING | Genes involved in Interferon Signaling |
0.9 | 3.6 | REACTOME METABOLISM OF NON CODING RNA | Genes involved in Metabolism of non-coding RNA |
0.8 | 3.2 | REACTOME GPCR DOWNSTREAM SIGNALING | Genes involved in GPCR downstream signaling |
0.6 | 1.2 | REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS | Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements |
0.5 | 0.9 | REACTOME HOST INTERACTIONS OF HIV FACTORS | Genes involved in Host Interactions of HIV factors |
0.5 | 0.5 | REACTOME G1 PHASE | Genes involved in G1 Phase |
0.4 | 1.7 | REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS | Genes involved in Glycerophospholipid biosynthesis |
0.4 | 0.7 | REACTOME MYD88 MAL CASCADE INITIATED ON PLASMA MEMBRANE | Genes involved in MyD88:Mal cascade initiated on plasma membrane |
0.3 | 2.4 | REACTOME METABOLISM OF RNA | Genes involved in Metabolism of RNA |
0.3 | 0.8 | REACTOME ETHANOL OXIDATION | Genes involved in Ethanol oxidation |
0.3 | 0.8 | REACTOME PLATELET ACTIVATION SIGNALING AND AGGREGATION | Genes involved in Platelet activation, signaling and aggregation |
0.2 | 1.7 | REACTOME UNWINDING OF DNA | Genes involved in Unwinding of DNA |
0.2 | 0.6 | REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS | Genes involved in Synthesis of substrates in N-glycan biosythesis |
0.2 | 1.3 | REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
0.2 | 1.8 | REACTOME FATTY ACID TRIACYLGLYCEROL AND KETONE BODY METABOLISM | Genes involved in Fatty acid, triacylglycerol, and ketone body metabolism |
0.1 | 0.4 | REACTOME SULFUR AMINO ACID METABOLISM | Genes involved in Sulfur amino acid metabolism |
0.1 | 0.4 | REACTOME AXON GUIDANCE | Genes involved in Axon guidance |
0.1 | 0.2 | REACTOME DEVELOPMENTAL BIOLOGY | Genes involved in Developmental Biology |
0.1 | 0.6 | REACTOME EXTENSION OF TELOMERES | Genes involved in Extension of Telomeres |
0.1 | 1.0 | REACTOME POST TRANSLATIONAL PROTEIN MODIFICATION | Genes involved in Post-translational protein modification |
0.1 | 0.8 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
0.1 | 0.4 | REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT | Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT) |
0.1 | 0.4 | REACTOME TRANSLATION | Genes involved in Translation |
0.1 | 0.2 | REACTOME GLYCOLYSIS | Genes involved in Glycolysis |
0.0 | 0.2 | REACTOME GLUCOSE METABOLISM | Genes involved in Glucose metabolism |
0.0 | 0.0 | REACTOME MRNA SPLICING | Genes involved in mRNA Splicing |