ISMARA results: Zfx

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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Zfx_Zfp711

Z-value: 2.35

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Transcription factors associated with Zfx_Zfp711

Gene Symbol	Gene ID	Gene Info
Zfx NCBI RGD Ensembl	ENSRNOG00000005624	zinc finger protein X-linked
Zfp711 NCBI RGD Ensembl	ENSRNOG00000022391	zinc finger protein 711

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Zfx	rn6_v1_chrX_-_63165759_63165759	0.27	7.1e-07	Click!
Zfp711	rn6_v1_chrX_+_84064427_84064427	-0.21	1.5e-04	Click!

Activity profile of Zfx_Zfp711 motif

Sorted Z-values of Zfx_Zfp711 motif

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Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr3_-_23020441 Show fit	98.26	ENSRNOT00000017651	Nr5a1 NCBI RGD Ensembl Show fit	nuclear receptor subfamily 5, group A, member 1
chr6_+_136536736 Show fit	47.35	ENSRNOT00000086594	Tdrd9 NCBI RGD Ensembl Show fit	tudor domain containing 9
chr3_+_172195844 Show fit	41.27	ENSRNOT00000034915	Npepl1 NCBI RGD Ensembl Show fit	aminopeptidase-like 1
chr1_-_142500367 Show fit	40.29	ENSRNOT00000015948 ENSRNOT00000089591	Crtc3 NCBI RGD Ensembl Show fit	CREB regulated transcription coactivator 3
chr11_+_66878658 Show fit	36.32	ENSRNOT00000003208	Eaf2 NCBI RGD Ensembl Show fit	ELL associated factor 2
chr1_+_221099998 Show fit	33.51	ENSRNOT00000028262	Ltbp3 NCBI RGD Ensembl Show fit	latent transforming growth factor beta binding protein 3
chr3_+_172420591 Show fit	30.06	ENSRNOT00000071215	Gnas NCBI RGD Ensembl Show fit	GNAS complex locus
chr19_-_26084679 Show fit	28.88	ENSRNOT00000046181	Rnaseh2a NCBI RGD Ensembl Show fit	ribonuclease H2, subunit A
chr5_+_155812105 Show fit	28.41	ENSRNOT00000039341	AABR07073181.1 NCBI RGD Ensembl Show fit
chr12_+_36871999 Show fit	28.31	ENSRNOT00000001334 ENSRNOT00000084236	Ncor2 NCBI RGD Ensembl Show fit	nuclear receptor co-repressor 2

Showing 1 to 10 of 200 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of Zfx_Zfp711

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
7.8	131.9	GO:0034587	piRNA metabolic process(GO:0034587)
0.7	123.1	GO:0008380	RNA splicing(GO:0008380)
29.2	116.7	GO:2000195	negative regulation of female gonad development(GO:2000195)
0.7	91.6	GO:0048515	spermatid differentiation(GO:0048515)
2.1	73.0	GO:0007339	binding of sperm to zona pellucida(GO:0007339)
2.6	67.5	GO:0034723	DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
3.2	64.8	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
1.4	58.9	GO:0010501	RNA secondary structure unwinding(GO:0010501)
2.1	47.2	GO:0060216	definitive hemopoiesis(GO:0060216)
0.5	47.2	GO:0035335	peptidyl-tyrosine dephosphorylation(GO:0035335)

Showing 1 to 10 of 1,171 entries

Gene overrepresentation in cellular component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.7	311.1	GO:0016604	nuclear body(GO:0016604)
0.3	252.8	GO:0005654	nucleoplasm(GO:0005654)
0.1	247.1	GO:0005634	nucleus(GO:0005634)
0.4	239.2	GO:0005730	nucleolus(GO:0005730)
1.6	184.5	GO:0090575	RNA polymerase II transcription factor complex(GO:0090575)
1.8	152.7	GO:0017053	transcriptional repressor complex(GO:0017053)
0.7	149.1	GO:0005667	transcription factor complex(GO:0005667)
0.5	141.4	GO:0005813	centrosome(GO:0005813)
2.1	106.6	GO:0005844	polysome(GO:0005844)
0.9	104.8	GO:0036064	ciliary basal body(GO:0036064)

Showing 1 to 10 of 398 entries

Gene overrepresentation in molecular function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.6	585.1	GO:0003677	DNA binding(GO:0003677)
0.8	390.1	GO:0001012	RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) RNA polymerase II regulatory region DNA binding(GO:0001012)
0.3	358.8	GO:0003676	nucleic acid binding(GO:0003676)
2.7	220.6	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
2.4	170.4	GO:0008186	RNA-dependent ATPase activity(GO:0008186)
0.5	106.6	GO:0003735	structural constituent of ribosome(GO:0003735)
0.9	103.3	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.6	103.2	GO:0003700	nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
4.0	101.0	GO:0046965	retinoid X receptor binding(GO:0046965)
0.9	97.3	GO:0003714	transcription corepressor activity(GO:0003714)

Showing 1 to 10 of 587 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.6	103.1	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
2.1	100.9	PID AURORA B PATHWAY	Aurora B signaling
1.8	79.0	PID ATM PATHWAY	ATM pathway
1.6	77.0	PID P53 REGULATION PATHWAY	p53 pathway
1.3	67.1	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
1.0	60.8	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
1.3	59.2	PID ILK PATHWAY	Integrin-linked kinase signaling
1.7	54.9	PID FOXM1 PATHWAY	FOXM1 transcription factor network
1.5	48.8	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
1.1	47.3	PID TELOMERASE PATHWAY	Regulation of Telomerase

Showing 1 to 10 of 116 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.7	146.2	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
1.1	140.9	REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION	Genes involved in 3' -UTR-mediated translational regulation
1.8	131.4	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
1.0	95.4	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
3.0	83.3	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
1.7	69.0	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
1.9	63.0	REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	Genes involved in Interactions of Vpr with host cellular proteins
2.6	62.8	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.8	62.2	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
1.3	56.7	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import

Showing 1 to 10 of 178 entries

Results for Zfx_Zfp711

Z-value: 2.35

Motif logo

Transcription factors associated with Zfx_Zfp711

Activity-expression correlation:

Activity profile of Zfx_Zfp711 motif

Sorted Z-values of Zfx_Zfp711 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of Zfx_Zfp711

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: