ISMARA results: Zfp263

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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Zfp263

Z-value: 0.93

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Transcription factors associated with Zfp263

Gene Symbol	Gene ID	Gene Info
Zfp263 NCBI RGD Ensembl	ENSRNOG00000007678	zinc finger protein 263

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Zfp263	rn6_v1_chr10_-_12030416_12030416	0.18	1.3e-03	Click!

Activity profile of Zfp263 motif

Sorted Z-values of Zfp263 motif

Top targets:

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Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr10_+_93520132 Show fit	34.71	ENSRNOT00000055137	Mrc2 NCBI RGD Ensembl Show fit	mannose receptor, C type 2
chr5_-_75319189 Show fit	25.60	ENSRNOT00000047200	Svep1 NCBI RGD Ensembl Show fit	sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
chr5_-_75319765 Show fit	25.21	ENSRNOT00000085698	Svep1 NCBI RGD Ensembl Show fit	sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
chr14_+_3506339 Show fit	21.62	ENSRNOT00000002867	Tgfbr3 NCBI RGD Ensembl Show fit	transforming growth factor beta receptor 3
chr10_+_89251370 Show fit	20.10	ENSRNOT00000076820	Aoc3 NCBI RGD Ensembl Show fit	amine oxidase, copper containing 3
chr1_+_261389804 Show fit	19.93	ENSRNOT00000064160	Marveld1 NCBI RGD Ensembl Show fit	MARVEL domain containing 1
chr3_-_107760550 Show fit	19.89	ENSRNOT00000077091 ENSRNOT00000051638	Meis2 NCBI RGD Ensembl Show fit	Meis homeobox 2
chr16_+_83522162 Show fit	16.82	ENSRNOT00000057386	Col4a1 NCBI RGD Ensembl Show fit	collagen type IV alpha 1 chain
chr8_+_48443767 Show fit	16.52	ENSRNOT00000010127	C1qtnf5 NCBI RGD Ensembl Show fit	C1q and tumor necrosis factor related protein 5
chr14_+_75852060 Show fit	16.52	ENSRNOT00000075975	Hs3st1 NCBI RGD Ensembl Show fit	heparan sulfate-glucosamine 3-sulfotransferase 1

Showing 1 to 10 of 200 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of Zfp263

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
2.0	47.4	GO:0030574	collagen catabolic process(GO:0030574)
7.2	21.6	GO:0007181	transforming growth factor beta receptor complex assembly(GO:0007181) cardiac fibroblast cell differentiation(GO:0060935) cardiac fibroblast cell development(GO:0060936) epicardium-derived cardiac fibroblast cell differentiation(GO:0060938) epicardium-derived cardiac fibroblast cell development(GO:0060939)
0.3	20.4	GO:0008542	visual learning(GO:0008542)
1.1	20.1	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.3	17.2	GO:0070206	protein trimerization(GO:0070206)
2.8	16.8	GO:0061304	retinal blood vessel morphogenesis(GO:0061304)
0.3	16.7	GO:0048488	synaptic vesicle endocytosis(GO:0048488)
5.5	16.4	GO:0007493	endodermal cell fate determination(GO:0007493) negative regulation of transforming growth factor beta2 production(GO:0032912)
1.5	16.2	GO:0070327	thyroid hormone transport(GO:0070327)
4.0	15.9	GO:0070315	G1 to G0 transition involved in cell differentiation(GO:0070315)

Showing 1 to 10 of 182 entries

Gene overrepresentation in cellular component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.2	88.4	GO:0005925	focal adhesion(GO:0005925)
0.1	70.9	GO:0005615	extracellular space(GO:0005615)
0.1	29.1	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.3	27.8	GO:0005902	microvillus(GO:0005902)
0.2	26.9	GO:0043195	terminal bouton(GO:0043195)
7.2	21.6	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
2.1	16.8	GO:0005587	collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
1.4	16.5	GO:0005796	Golgi lumen(GO:0005796)
0.5	14.5	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.0	14.0	GO:0016607	nuclear speck(GO:0016607)

Showing 1 to 10 of 77 entries

Gene overrepresentation in molecular function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.2	114.0	GO:0005509	calcium ion binding(GO:0005509)
0.3	40.5	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.4	34.7	GO:0005518	collagen binding(GO:0005518)
0.1	28.1	GO:0001077	transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
2.4	23.7	GO:0005114	type II transforming growth factor beta receptor binding(GO:0005114)
1.8	20.1	GO:0008131	primary amine oxidase activity(GO:0008131)
0.5	18.0	GO:0001103	RNA polymerase II repressing transcription factor binding(GO:0001103)
1.3	17.3	GO:0004089	carbonate dehydratase activity(GO:0004089)
1.2	16.8	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.3	16.7	GO:0035255	ionotropic glutamate receptor binding(GO:0035255)

Showing 1 to 10 of 122 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.3	50.2	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.6	42.7	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions
0.1	32.2	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.4	23.7	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.4	22.6	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.1	19.8	NABA SECRETED FACTORS	Genes encoding secreted soluble factors
0.6	18.2	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.3	17.0	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.5	14.9	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.6	14.8	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium

Showing 1 to 10 of 42 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.5	31.7	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.6	28.9	REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.5	24.3	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.7	19.6	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.6	17.2	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.1	16.7	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.2	16.1	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1	14.7	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.7	13.1	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.2	13.0	REACTOME SIGNALING BY PDGF	Genes involved in Signaling by PDGF

Showing 1 to 10 of 48 entries

Results for Zfp263

Z-value: 0.93

Motif logo

Transcription factors associated with Zfp263

Activity-expression correlation:

Activity profile of Zfp263 motif

Sorted Z-values of Zfp263 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of Zfp263

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: