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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Zfp263

Z-value: 0.93

Motif logo

Transcription factors associated with Zfp263

Gene Symbol Gene ID Gene Info
ENSRNOG00000007678 zinc finger protein 263

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Zfp263rn6_v1_chr10_-_12030416_120304160.181.3e-03Click!

Activity profile of Zfp263 motif

Sorted Z-values of Zfp263 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr10_+_93520132 34.71 ENSRNOT00000055137
mannose receptor, C type 2
chr5_-_75319189 25.60 ENSRNOT00000047200
sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
chr5_-_75319765 25.21 ENSRNOT00000085698
sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
chr14_+_3506339 21.62 ENSRNOT00000002867
transforming growth factor beta receptor 3
chr10_+_89251370 20.10 ENSRNOT00000076820
amine oxidase, copper containing 3
chr1_+_261389804 19.93 ENSRNOT00000064160
MARVEL domain containing 1
chr3_-_107760550 19.89 ENSRNOT00000077091
ENSRNOT00000051638
Meis homeobox 2
chr16_+_83522162 16.82 ENSRNOT00000057386
collagen type IV alpha 1 chain
chr8_+_48443767 16.52 ENSRNOT00000010127
C1q and tumor necrosis factor related protein 5
chr14_+_75852060 16.52 ENSRNOT00000075975
heparan sulfate-glucosamine 3-sulfotransferase 1
chr1_-_246785360 16.36 ENSRNOT00000019816
GLIS family zinc finger 3
chrX_-_74706214 16.21 ENSRNOT00000040637
solute carrier family 16 member 2
chr15_+_2374582 15.92 ENSRNOT00000019644
zinc finger protein 503
chr10_+_84147836 15.36 ENSRNOT00000010527
homeo box B6
chr2_+_182723854 15.17 ENSRNOT00000012658
secreted frizzled-related protein 2
chr17_+_4846789 14.53 ENSRNOT00000073271
growth arrest-specific 1
chr6_-_99843245 13.72 ENSRNOT00000080270
glutathione peroxidase 2
chr4_+_6931495 12.95 ENSRNOT00000079770
WD repeat domain 86
chr13_-_86671515 12.75 ENSRNOT00000082869

chr20_+_13670066 12.70 ENSRNOT00000031400
stromelysin-3
chr1_-_56683731 12.63 ENSRNOT00000014552
thrombospondin 2
chr7_-_11648322 12.60 ENSRNOT00000026871
growth arrest and DNA-damage-inducible, beta
chr10_-_62009582 12.59 ENSRNOT00000004143
HIC ZBTB transcriptional repressor 1
chr9_-_70787913 12.56 ENSRNOT00000072007
ENSRNOT00000017901
Kruppel like factor 7
Kruppel like factor 7
chr6_+_3657325 12.47 ENSRNOT00000010927
transmembrane protein 178A
chr7_-_117151256 12.26 ENSRNOT00000078846
nuclear receptor binding protein 2
chr4_+_26470864 12.03 ENSRNOT00000021979
frizzled class receptor 1
chr2_+_125752130 11.72 ENSRNOT00000038703
FAT atypical cadherin 4
chr4_-_66002444 11.50 ENSRNOT00000018645
zinc finger CCCH-type containing, antiviral 1 like
chr14_+_19866408 11.34 ENSRNOT00000060465
ADAM metallopeptidase with thrombospondin type 1, motif 3
chr18_-_31430973 11.32 ENSRNOT00000026065
protocadherin 12
chr18_+_57286322 11.25 ENSRNOT00000026174
SH3 domain and tetratricopeptide repeats 2
chr11_-_25078740 11.07 ENSRNOT00000002109
cysteine and tyrosine rich 1
chr13_-_90676629 10.92 ENSRNOT00000058143
ATPase Na+/K+ transporting subunit alpha 2
chr1_-_222468896 10.77 ENSRNOT00000028754
cytochrome c oxidase subunit 8A
chr4_+_157836912 10.71 ENSRNOT00000067271
sodium channel epithelial 1 alpha subunit
chr1_-_131454689 10.27 ENSRNOT00000014152
nuclear receptor subfamily 2, group F, member 2
chr11_-_65845418 10.16 ENSRNOT00000091057
follistatin-like 1
chr5_-_173611202 10.01 ENSRNOT00000047854
agrin
chr10_+_72272248 9.65 ENSRNOT00000003908
carbonic anhydrase 4
chr10_+_86303727 9.63 ENSRNOT00000037752
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr8_+_22750336 9.54 ENSRNOT00000013496
low density lipoprotein receptor
chr7_+_143707237 9.53 ENSRNOT00000074212
tensin 2
chr14_+_79538911 9.47 ENSRNOT00000009960
sortilin-related VPS10 domain containing receptor 2
chr12_+_37490584 9.30 ENSRNOT00000001401
ENSRNOT00000090831
Rab interacting lysosomal protein-like 1
chr2_-_61949926 9.09 ENSRNOT00000025966
natriuretic peptide receptor 3
chrX_+_112020646 9.03 ENSRNOT00000079841
midline 2
chr6_-_92527711 8.83 ENSRNOT00000007529
ninein
chr3_+_72540538 8.66 ENSRNOT00000012379
apelin receptor
chr14_+_100217289 8.65 ENSRNOT00000077171
ENSRNOT00000007104
cannabinoid receptor interacting protein 1
chr9_-_82699551 8.63 ENSRNOT00000020673
obscurin-like 1
chr4_-_64981384 8.62 ENSRNOT00000017338
cAMP responsive element binding protein 3-like 2
chrX_+_40460047 8.56 ENSRNOT00000010970
phosphate regulating endopeptidase homolog, X-linked
chr1_+_81328183 8.44 ENSRNOT00000074985
ENSRNOT00000075167
plasminogen activator, urokinase receptor
chr18_+_2416871 8.42 ENSRNOT00000081399
GATA binding protein 6
chr2_+_189922996 8.41 ENSRNOT00000016499
S100 calcium binding protein A16
chrX_-_68562873 8.38 ENSRNOT00000076193
oligophrenin 1
chrX_-_68563137 8.33 ENSRNOT00000034772
oligophrenin 1
chr18_+_2416552 7.95 ENSRNOT00000030726
GATA binding protein 6
chr13_-_97173469 7.79 ENSRNOT00000017784
kinesin family member 26B
chr15_-_48445588 7.69 ENSRNOT00000077197
ENSRNOT00000018583
exostosin-like glycosyltransferase 3
chr16_-_81434038 7.68 ENSRNOT00000067508
RAS p21 protein activator 3
chr8_+_72405748 7.67 ENSRNOT00000023952
carbonic anhydrase 12
chr1_+_225129097 7.65 ENSRNOT00000026938
echinoderm microtubule associated protein like 3
chr7_-_47586137 7.64 ENSRNOT00000006086
transmembrane and tetratricopeptide repeat containing 2
chr4_+_155653718 7.60 ENSRNOT00000065419
forkhead box J2
chr6_-_95934296 7.57 ENSRNOT00000034338
SIX homeobox 1
chr6_-_110904288 7.50 ENSRNOT00000014645
interferon regulatory factor 2 binding protein-like
chr1_-_221370322 7.24 ENSRNOT00000028431
calpain 1
chr12_-_19592000 7.17 ENSRNOT00000001855
galactose-3-O-sulfotransferase 4
chr8_-_47393503 6.98 ENSRNOT00000059868
Rho guanine nucleotide exchange factor 12
chr2_-_172459165 6.88 ENSRNOT00000057473
schwannomin interacting protein 1
chr7_-_62972084 6.87 ENSRNOT00000064251
methionine sulfoxide reductase B3
chr6_-_51356383 6.85 ENSRNOT00000012415
protein kinase cAMP-dependent type 2 regulatory subunit beta
chrX_-_15693473 6.78 ENSRNOT00000013758
prickle planar cell polarity protein 3
chr7_-_142210738 6.76 ENSRNOT00000006095
POU class 6 homeobox 1
chr7_+_140742418 6.62 ENSRNOT00000089211
peripherin
chr17_-_70045865 6.37 ENSRNOT00000031504
calmodulin-like 5
chr16_-_40555576 6.16 ENSRNOT00000015529
vascular endothelial growth factor C
chr14_-_85484275 6.15 ENSRNOT00000083770
kringle containing transmembrane protein 1
chr15_-_2966576 6.06 ENSRNOT00000070893
ENSRNOT00000017383
lysine acetyltransferase 6B
chr7_+_41475163 5.78 ENSRNOT00000037844
dual specificity phosphatase 6
chr18_+_30885789 5.69 ENSRNOT00000044434
protocadherin gamma subfamily A, 9
chr2_-_207541645 5.66 ENSRNOT00000019680
CTTNBP2 N-terminal like
chr1_+_165724451 5.65 ENSRNOT00000025827
family with sequence similarity 168, member A
chr5_-_159662754 5.57 ENSRNOT00000045226
SUZ RNA binding domain containing 1
chr18_+_30869628 5.56 ENSRNOT00000060470
protocadherin gamma subfamily B, 4
chrX_+_77076106 5.56 ENSRNOT00000091527
ENSRNOT00000089381
ATPase copper transporting alpha
chr1_-_214317466 5.52 ENSRNOT00000048817
DEAF1 transcription factor
chr15_-_20783063 5.52 ENSRNOT00000083268
bone morphogenetic protein 4
chr18_-_5314511 5.52 ENSRNOT00000022637
ENSRNOT00000079682
zinc finger protein 521
chr1_+_115975324 5.49 ENSRNOT00000080907
ATPase phospholipid transporting 10A (putative)
chr12_+_29266602 5.45 ENSRNOT00000076194
Williams-Beuren syndrome chromosome region 17
chr3_+_126335863 5.39 ENSRNOT00000028904
bone morphogenetic protein 2
chr5_+_1417478 5.37 ENSRNOT00000008153
ENSRNOT00000085564
junctophilin 1
chr15_-_43542939 5.32 ENSRNOT00000012996
dihydropyrimidinase-like 2
chr4_-_49439867 5.32 ENSRNOT00000090583
family with sequence similarity 3, member C
chr9_-_15214596 5.26 ENSRNOT00000039102
transcription factor EB
chr9_+_54212767 5.25 ENSRNOT00000078073
ENSRNOT00000090026
glutaminase
chr18_-_6474990 5.20 ENSRNOT00000061504
potassium channel tetramerization domain containing 1
chr3_+_160908769 5.19 ENSRNOT00000030054
Sys1 golgi trafficking protein
chr1_+_177764445 5.18 ENSRNOT00000037185
Ras association domain family member 10
chr15_+_34493138 5.15 ENSRNOT00000089584
ENSRNOT00000027789
nuclear factor of activated T-cells 4
chr15_+_57340579 5.14 ENSRNOT00000015467
zinc finger CCCH type containing 13
chr1_-_142183884 5.12 ENSRNOT00000016032
FES proto-oncogene, tyrosine kinase
chr13_+_49195325 5.09 ENSRNOT00000004810
dual serine/threonine and tyrosine protein kinase
chr4_+_22859622 5.04 ENSRNOT00000073501
ENSRNOT00000068410
ADAM metallopeptidase domain 22
chr7_+_145117951 5.03 ENSRNOT00000055272
phosphodiesterase 1B
chr5_-_144779212 4.91 ENSRNOT00000016230
neurochondrin
chr2_+_188748359 4.85 ENSRNOT00000028038
SHC adaptor protein 1
chr1_+_226091774 4.78 ENSRNOT00000027693
fatty acid desaturase 3
chr13_+_52413241 4.77 ENSRNOT00000035157

chr17_+_28504623 4.76 ENSRNOT00000021568
coagulation factor XIII A1 chain
chr6_-_107678156 4.70 ENSRNOT00000014158
ELM2 and Myb/SANT domain containing 1
chr5_-_137104993 4.66 ENSRNOT00000027271
protein tyrosine phosphatase, receptor type, F
chr6_+_57516713 4.59 ENSRNOT00000063874
diacylglycerol kinase, beta
chr1_+_84293102 4.56 ENSRNOT00000028468
SERTA domain containing 1
chr4_-_77706994 4.51 ENSRNOT00000038517
zinc finger protein 777
chr2_+_95320283 4.38 ENSRNOT00000015537
hes-related family bHLH transcription factor with YRPW motif 1
chr1_+_101859346 4.36 ENSRNOT00000028627
KDEL endoplasmic reticulum protein retention receptor 1
chr20_+_6018374 4.31 ENSRNOT00000000621
mitogen activated protein kinase 13
chr18_+_53915807 4.28 ENSRNOT00000026543
ADAM metallopeptidase with thrombospondin type 1 motif, 19
chr7_-_143852119 4.25 ENSRNOT00000016801
retinoic acid receptor, gamma
chr4_-_82160240 4.19 ENSRNOT00000038775
ENSRNOT00000058985
homeo box A4
chr4_+_7076759 4.18 ENSRNOT00000066598
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chrX_-_34794589 4.17 ENSRNOT00000008703
retinoic acid induced 2
chr3_+_148386189 4.15 ENSRNOT00000011255
myosin light chain kinase 2
chr1_-_207171760 4.12 ENSRNOT00000047069
family with sequence similarity 196, member A
chr8_+_36625733 4.09 ENSRNOT00000016248
cell adhesion associated, oncogene regulated
chr3_+_72134731 4.07 ENSRNOT00000083592
yippee-like 4
chr15_-_33589522 4.01 ENSRNOT00000022514
embryonal Fyn-associated substrate
chr10_+_110893457 4.00 ENSRNOT00000088495
meteorin-like, glial cell differentiation regulator
chr4_+_66405166 3.99 ENSRNOT00000077486
ENSRNOT00000067097
C-type lectin domain family 2, member L
chr19_-_26094756 3.98 ENSRNOT00000067780
JunB proto-oncogene, AP-1 transcription factor subunit
chr3_+_176093640 3.97 ENSRNOT00000086541
opioid growth factor receptor
chr18_+_30375798 3.97 ENSRNOT00000060497
protocadherin beta 2
chr6_+_53401109 3.94 ENSRNOT00000014763
twist family bHLH transcription factor 1
chr10_+_46511271 3.93 ENSRNOT00000080828
retinoic acid induced 1
chr4_-_148845267 3.89 ENSRNOT00000037397
transmembrane protein 72
chr4_+_57050214 3.87 ENSRNOT00000025165
adenosylhomocysteinase-like 2
chr1_+_262987957 3.87 ENSRNOT00000023111
ectonucleoside triphosphate diphosphohydrolase 7
chr9_+_16427589 3.85 ENSRNOT00000091809
GLTSCR1-like
chr20_-_2211995 3.83 ENSRNOT00000077201
tripartite motif-containing 26
chr7_-_144993652 3.82 ENSRNOT00000087748
integrin subunit alpha 5
chr10_+_85744568 3.81 ENSRNOT00000005522
LIM and SH3 protein 1
chrX_+_123751293 3.79 ENSRNOT00000089883
NFKB activating protein
chr1_+_114258719 3.77 ENSRNOT00000088459
ENSRNOT00000016376
cytoplasmic FMR1 interacting protein 1
chr15_-_4022223 3.77 ENSRNOT00000081997
zinc finger, SWIM-type containing 8
chr4_+_83713666 3.77 ENSRNOT00000086473
cAMP responsive element binding protein 5
chr19_+_39067363 3.64 ENSRNOT00000083515
hyaluronan synthase 3
chr3_+_117938500 3.61 ENSRNOT00000042411
EP300 interacting inhibitor of differentiation 1
chr13_+_98615287 3.61 ENSRNOT00000004032
inositol-trisphosphate 3-kinase B
chr1_-_64147251 3.60 ENSRNOT00000088502
CCR4-NOT transcription complex, subunit 3
chr12_-_17972737 3.60 ENSRNOT00000001783
FAM20C, golgi associated secretory pathway kinase
chr10_+_103934797 3.59 ENSRNOT00000035865
cerebellar degeneration-related protein 2-like
chr7_-_51353068 3.50 ENSRNOT00000008222
pro-apoptotic WT1 regulator
chr3_+_155160481 3.45 ENSRNOT00000021133
protein phosphatase 1, regulatory subunit 16B
chr11_+_30550141 3.44 ENSRNOT00000002866
hormonally upregulated Neu-associated kinase
chr14_+_36687134 3.44 ENSRNOT00000002879
ubiquitin specific peptidase 46
chr6_+_123361864 3.44 ENSRNOT00000057577

chr2_-_192960294 3.42 ENSRNOT00000012420
late cornified envelope protein 5A-like
chr14_+_18231860 3.41 ENSRNOT00000003686
betacellulin
chr1_+_274766283 3.34 ENSRNOT00000071541
adrenoceptor alpha 2A
chr6_+_76675418 3.29 ENSRNOT00000076169
ENSRNOT00000010948
ENSRNOT00000082286
breast cancer metastasis-suppressor 1-like
breast cancer metastasis-suppressor 1-like
chr5_+_58855773 3.27 ENSRNOT00000072869
RUN and SH3 domain containing 2
chr17_+_56109549 3.14 ENSRNOT00000022190
mitogen-activated protein kinase kinase kinase 8
chrX_-_72370044 3.12 ENSRNOT00000004224
histone deacetylase 8
chr1_+_220322940 3.05 ENSRNOT00000074972
beta-1,4-glucuronyltransferase 1
chr4_+_140703619 3.01 ENSRNOT00000009563
basic helix-loop-helix family, member e40
chr15_+_15275541 3.01 ENSRNOT00000012153
calcium dependent secretion activator
chr4_-_28953067 2.98 ENSRNOT00000013989
tissue factor pathway inhibitor 2
chr12_-_22021851 2.98 ENSRNOT00000039280
TSC22 domain family, member 4
chr11_+_74834050 2.98 ENSRNOT00000002333
ATPase 13A4
chr1_-_57327379 2.91 ENSRNOT00000080429
delta like canonical Notch ligand 1
chr8_+_63036976 2.90 ENSRNOT00000011383
stomatin like 1
chr10_+_105156632 2.89 ENSRNOT00000086288
galanin receptor 2
chr8_+_71822129 2.88 ENSRNOT00000089147
death-associated protein kinase 2
chr1_-_170318935 2.87 ENSRNOT00000024119
protein kinase C, delta binding protein
chr7_-_139907640 2.85 ENSRNOT00000045473
zinc finger protein 641
chr2_+_54191538 2.82 ENSRNOT00000019524
phosphatidylinositol-specific phospholipase C, X domain containing 3
chr4_-_157439507 2.81 ENSRNOT00000081802
parathymosin
chr16_-_48692476 2.79 ENSRNOT00000013118
interferon regulatory factor 2
chr12_-_22726982 2.76 ENSRNOT00000001921
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
chr1_+_266358728 2.75 ENSRNOT00000027118
WW domain binding protein 1-like
chr11_-_90406797 2.74 ENSRNOT00000073049
snail family transcriptional repressor 2
chr9_-_93377643 2.71 ENSRNOT00000024712
nucleolin
chr10_-_72142533 2.69 ENSRNOT00000030885
mitochondrial rRNA methyltransferase 1
chr7_-_92882068 2.68 ENSRNOT00000037809
exostosin glycosyltransferase 1
chr18_-_37776453 2.66 ENSRNOT00000087876
dihydropyrimidinase-like 3
chr17_+_72429618 2.66 ENSRNOT00000026187
GATA binding protein 3
chrX_-_111325186 2.57 ENSRNOT00000086785
RNA binding motif protein 41
chr3_+_95133713 2.55 ENSRNOT00000067940
Wilms tumor 1
chr7_-_143863186 2.54 ENSRNOT00000017096
retinoic acid receptor, gamma
chr10_-_107386072 2.50 ENSRNOT00000004290
TIMP metallopeptidase inhibitor 2
chr7_+_77763512 2.49 ENSRNOT00000006411
brain and acute leukemia, cytoplasmic
chrX_+_128493614 2.48 ENSRNOT00000044240
stromal antigen 2
chr12_+_12227010 2.42 ENSRNOT00000060843
ENSRNOT00000092610
BAI1-associated protein 2-like 1
chr18_+_76559811 2.37 ENSRNOT00000084621
par-6 family cell polarity regulator gamma
chr2_-_204032023 2.37 ENSRNOT00000040430
ATPase Na+/K+ transporting subunit alpha 1
chr12_-_46989876 2.36 ENSRNOT00000079043
ENSRNOT00000001534
TP53 regulated inhibitor of apoptosis 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Zfp263

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
7.2 21.6 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181) cardiac fibroblast cell differentiation(GO:0060935) cardiac fibroblast cell development(GO:0060936) epicardium-derived cardiac fibroblast cell differentiation(GO:0060938) epicardium-derived cardiac fibroblast cell development(GO:0060939)
5.5 16.4 GO:0007493 endodermal cell fate determination(GO:0007493) negative regulation of transforming growth factor beta2 production(GO:0032912)
5.1 15.2 GO:2000041 negative regulation of mesodermal cell fate specification(GO:0042662) regulation of midbrain dopaminergic neuron differentiation(GO:1904956) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
4.6 13.7 GO:0009609 response to symbiotic bacterium(GO:0009609)
4.0 12.0 GO:0035425 autocrine signaling(GO:0035425)
4.0 15.9 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
3.9 11.7 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
3.8 11.3 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
3.4 10.3 GO:0060849 lymphatic endothelial cell fate commitment(GO:0060838) regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
3.3 10.0 GO:2000539 positive regulation of synaptic growth at neuromuscular junction(GO:0045887) regulation of sodium:potassium-exchanging ATPase activity(GO:1903406) regulation of protein geranylgeranylation(GO:2000539) positive regulation of protein geranylgeranylation(GO:2000541)
3.1 9.3 GO:1903445 protein transport from ciliary membrane to plasma membrane(GO:1903445)
3.1 6.2 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
2.9 8.6 GO:1904383 response to sodium phosphate(GO:1904383)
2.8 16.8 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
2.7 10.9 GO:1903279 regulation of calcium:sodium antiporter activity(GO:1903279)
2.7 10.9 GO:0072138 BMP signaling pathway involved in heart induction(GO:0003130) endodermal-mesodermal cell signaling(GO:0003133) endodermal-mesodermal cell signaling involved in heart induction(GO:0003134) mesenchymal cell proliferation involved in ureteric bud development(GO:0072138)
2.7 2.7 GO:0061209 cell proliferation involved in mesonephros development(GO:0061209)
2.5 7.6 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582)
2.4 9.5 GO:0010899 regulation of phosphatidylcholine catabolic process(GO:0010899) receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118)
2.3 6.9 GO:0030091 protein repair(GO:0030091)
2.3 6.8 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
2.0 47.4 GO:0030574 collagen catabolic process(GO:0030574)
1.9 7.8 GO:0072092 ureteric bud invasion(GO:0072092)
1.7 5.2 GO:0006543 glutamine catabolic process(GO:0006543)
1.7 5.2 GO:2000297 negative regulation of synapse maturation(GO:2000297)
1.5 16.2 GO:0070327 thyroid hormone transport(GO:0070327)
1.5 4.4 GO:2000820 negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)
1.5 2.9 GO:0045168 cell-cell signaling involved in cell fate commitment(GO:0045168)
1.5 14.5 GO:0042473 outer ear morphogenesis(GO:0042473)
1.4 5.8 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
1.4 8.4 GO:2001268 negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
1.4 5.6 GO:0034760 negative regulation of iron ion transmembrane transport(GO:0034760) elastin biosynthetic process(GO:0051542) regulation of cytochrome-c oxidase activity(GO:1904959)
1.4 4.2 GO:0031446 regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448)
1.4 9.6 GO:0007621 negative regulation of female receptivity(GO:0007621)
1.4 6.9 GO:0097332 response to antipsychotic drug(GO:0097332)
1.4 2.7 GO:0003273 cell migration involved in endocardial cushion formation(GO:0003273)
1.3 3.9 GO:0033128 negative regulation of histone phosphorylation(GO:0033128) negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
1.3 5.2 GO:1902606 regulation of large conductance calcium-activated potassium channel activity(GO:1902606) positive regulation of large conductance calcium-activated potassium channel activity(GO:1902608)
1.3 2.5 GO:0072125 negative regulation of glomerular mesangial cell proliferation(GO:0072125) negative regulation of glomerulus development(GO:0090194)
1.2 3.6 GO:0097187 dentinogenesis(GO:0097187)
1.2 3.5 GO:1904457 hindgut contraction(GO:0043133) regulation of hindgut contraction(GO:0043134) positive regulation of neuronal action potential(GO:1904457)
1.1 3.4 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
1.1 9.1 GO:0002158 osteoclast proliferation(GO:0002158)
1.1 11.2 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
1.1 20.1 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
1.0 4.2 GO:0003219 cardiac right ventricle formation(GO:0003219)
1.0 3.1 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
1.0 11.1 GO:0072393 microtubule anchoring at microtubule organizing center(GO:0072393)
1.0 2.9 GO:2000424 regulation of eosinophil chemotaxis(GO:2000422) positive regulation of eosinophil chemotaxis(GO:2000424)
0.9 4.7 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.9 2.8 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.9 3.6 GO:0046379 hyaluranon cable assembly(GO:0036118) extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.9 7.2 GO:0097264 self proteolysis(GO:0097264)
0.9 10.8 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.9 2.7 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.9 8.6 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.9 7.7 GO:0055064 chloride ion homeostasis(GO:0055064)
0.8 9.0 GO:0035372 protein localization to microtubule(GO:0035372)
0.8 4.1 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.8 9.6 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.7 12.6 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.7 5.1 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.7 2.1 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.7 3.3 GO:0050955 thermoception(GO:0050955)
0.7 2.0 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.6 4.4 GO:0006621 protein retention in ER lumen(GO:0006621)
0.6 11.3 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.6 13.5 GO:0014850 response to muscle activity(GO:0014850)
0.6 1.7 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.6 5.0 GO:0036005 response to macrophage colony-stimulating factor(GO:0036005) cellular response to macrophage colony-stimulating factor stimulus(GO:0036006)
0.6 3.9 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.6 2.2 GO:2000587 negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.5 3.8 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.5 2.1 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.5 3.6 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.5 12.5 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.5 2.0 GO:0051344 negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.5 2.4 GO:0036376 sodium ion export from cell(GO:0036376)
0.5 2.3 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.5 1.8 GO:0048319 axial mesoderm morphogenesis(GO:0048319)
0.4 3.6 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.4 3.0 GO:0099525 presynaptic dense core granule exocytosis(GO:0099525)
0.4 3.4 GO:0035810 positive regulation of urine volume(GO:0035810)
0.4 2.1 GO:0001555 oocyte growth(GO:0001555)
0.4 1.6 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
0.4 4.8 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.4 2.0 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.4 2.7 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.4 7.5 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.4 1.4 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.4 1.4 GO:0072709 cellular response to sorbitol(GO:0072709)
0.4 2.5 GO:1905049 negative regulation of metallopeptidase activity(GO:1905049)
0.3 6.3 GO:0001553 luteinization(GO:0001553)
0.3 3.8 GO:2000811 negative regulation of anoikis(GO:2000811)
0.3 5.2 GO:0000042 protein targeting to Golgi(GO:0000042)
0.3 3.4 GO:0008343 adult feeding behavior(GO:0008343)
0.3 2.4 GO:0022007 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.3 5.0 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.3 16.7 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.3 5.3 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
0.3 10.7 GO:0055078 sodium ion homeostasis(GO:0055078)
0.3 20.4 GO:0008542 visual learning(GO:0008542)
0.3 10.7 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.3 1.3 GO:0010045 response to nickel cation(GO:0010045)
0.3 5.5 GO:1900424 regulation of defense response to bacterium(GO:1900424)
0.3 9.7 GO:0006730 one-carbon metabolic process(GO:0006730)
0.3 2.9 GO:2000650 negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.3 1.4 GO:0042758 long-chain fatty acid catabolic process(GO:0042758)
0.3 3.9 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.3 2.5 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.3 17.2 GO:0070206 protein trimerization(GO:0070206)
0.3 3.8 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.3 1.8 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.2 0.7 GO:1902714 negative regulation of interferon-gamma secretion(GO:1902714)
0.2 2.7 GO:0051764 actin crosslink formation(GO:0051764)
0.2 5.5 GO:0045332 phospholipid translocation(GO:0045332)
0.2 2.2 GO:0090527 actin filament reorganization(GO:0090527)
0.2 0.6 GO:0051012 microtubule sliding(GO:0051012) negative regulation of nonmotile primary cilium assembly(GO:1902856)
0.2 1.4 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.2 1.0 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.2 7.7 GO:0006024 aminoglycan biosynthetic process(GO:0006023) glycosaminoglycan biosynthetic process(GO:0006024)
0.2 0.5 GO:2001226 negative regulation of chloride transport(GO:2001226)
0.2 1.2 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.2 1.6 GO:0015732 prostaglandin transport(GO:0015732)
0.2 1.9 GO:0042754 negative regulation of circadian rhythm(GO:0042754)
0.2 3.8 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.1 0.4 GO:0009106 lipoate metabolic process(GO:0009106)
0.1 13.0 GO:0016525 negative regulation of angiogenesis(GO:0016525)
0.1 7.7 GO:0034605 cellular response to heat(GO:0034605)
0.1 3.0 GO:0071498 cellular response to fluid shear stress(GO:0071498)
0.1 2.1 GO:0060746 parental behavior(GO:0060746)
0.1 1.9 GO:0030238 male sex determination(GO:0030238)
0.1 0.5 GO:2001274 negative regulation of glucose import in response to insulin stimulus(GO:2001274)
0.1 0.3 GO:0032763 regulation of mast cell cytokine production(GO:0032763)
0.1 1.4 GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372)
0.1 8.2 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.1 5.6 GO:0045739 base-excision repair(GO:0006284) positive regulation of DNA repair(GO:0045739)
0.1 7.7 GO:0009247 glycolipid biosynthetic process(GO:0009247)
0.1 1.8 GO:1903830 magnesium ion transport(GO:0015693) magnesium ion transmembrane transport(GO:1903830)
0.1 3.0 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.1 15.4 GO:0034101 erythrocyte homeostasis(GO:0034101)
0.1 13.0 GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage(GO:0008630)
0.1 0.9 GO:0045630 negative regulation of granulocyte differentiation(GO:0030853) positive regulation of T-helper 2 cell differentiation(GO:0045630) chondroblast differentiation(GO:0060591)
0.1 3.6 GO:0035065 regulation of histone acetylation(GO:0035065)
0.1 1.7 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.1 6.4 GO:0030279 negative regulation of ossification(GO:0030279)
0.1 5.5 GO:0000186 activation of MAPKK activity(GO:0000186)
0.1 3.9 GO:0045453 bone resorption(GO:0045453)
0.1 2.2 GO:1901798 positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.1 5.7 GO:0043966 histone H3 acetylation(GO:0043966)
0.1 1.2 GO:0071397 cellular response to cholesterol(GO:0071397)
0.1 4.4 GO:0032410 negative regulation of transporter activity(GO:0032410)
0.1 3.8 GO:0060612 adipose tissue development(GO:0060612)
0.1 7.3 GO:0006970 response to osmotic stress(GO:0006970)
0.1 1.3 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1 3.4 GO:0018149 peptide cross-linking(GO:0018149)
0.1 4.8 GO:0035094 response to nicotine(GO:0035094)
0.1 0.8 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.1 1.1 GO:0031167 rRNA methylation(GO:0031167)
0.1 4.1 GO:0046834 lipid phosphorylation(GO:0046834)
0.1 1.1 GO:0006907 pinocytosis(GO:0006907)
0.1 9.0 GO:0048813 dendrite morphogenesis(GO:0048813)
0.1 1.7 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.1 3.4 GO:0007569 cell aging(GO:0007569)
0.1 2.4 GO:0032543 mitochondrial translation(GO:0032543)
0.0 6.4 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.2 GO:0045410 positive regulation of interleukin-6 biosynthetic process(GO:0045410)
0.0 0.4 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.0 0.8 GO:0061036 positive regulation of cartilage development(GO:0061036)
0.0 0.0 GO:0009176 pyrimidine deoxyribonucleoside monophosphate metabolic process(GO:0009176) dUMP metabolic process(GO:0046078)
0.0 3.2 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 1.6 GO:0007004 RNA-dependent DNA biosynthetic process(GO:0006278) telomere maintenance via telomerase(GO:0007004)
0.0 1.9 GO:1903363 negative regulation of cellular protein catabolic process(GO:1903363)
0.0 0.1 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.4 GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059) negative regulation of ERBB signaling pathway(GO:1901185)
0.0 1.0 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0 1.0 GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:0000288)
0.0 1.9 GO:0008033 tRNA processing(GO:0008033)
0.0 2.7 GO:0042594 response to starvation(GO:0042594)
0.0 0.1 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.9 GO:0030326 embryonic limb morphogenesis(GO:0030326) embryonic appendage morphogenesis(GO:0035113)
0.0 0.1 GO:0051561 positive regulation of mitochondrial calcium ion concentration(GO:0051561)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
7.2 21.6 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
2.1 16.8 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
1.8 5.4 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
1.7 6.6 GO:0044299 C-fiber(GO:0044299)
1.4 8.6 GO:1990393 3M complex(GO:1990393)
1.4 16.5 GO:0005796 Golgi lumen(GO:0005796)
1.3 8.8 GO:0036449 microtubule minus-end(GO:0036449)
1.2 3.6 GO:0036117 hyaluranon cable(GO:0036117)
1.2 9.5 GO:0097443 sorting endosome(GO:0097443)
1.1 13.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.8 4.0 GO:0035976 AP1 complex(GO:0035976)
0.8 6.9 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.7 3.6 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.7 7.1 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.7 2.1 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.7 10.8 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.7 10.0 GO:0043083 synaptic cleft(GO:0043083)
0.5 9.7 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.5 12.6 GO:0031091 platelet alpha granule(GO:0031091)
0.5 14.5 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.5 7.7 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.4 3.8 GO:0031209 SCAR complex(GO:0031209)
0.4 2.0 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.4 2.7 GO:0001651 dense fibrillar component(GO:0001651)
0.4 2.2 GO:0005642 annulate lamellae(GO:0005642)
0.3 7.1 GO:0034706 sodium channel complex(GO:0034706)
0.3 27.8 GO:0005902 microvillus(GO:0005902)
0.2 2.6 GO:0071564 npBAF complex(GO:0071564)
0.2 4.4 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.2 26.9 GO:0043195 terminal bouton(GO:0043195)
0.2 3.0 GO:0031045 dense core granule(GO:0031045)
0.2 11.4 GO:0016328 lateral plasma membrane(GO:0016328)
0.2 88.4 GO:0005925 focal adhesion(GO:0005925)
0.2 1.1 GO:0031313 extrinsic component of endosome membrane(GO:0031313) tubular endosome(GO:0097422)
0.2 2.1 GO:0044666 MLL3/4 complex(GO:0044666)
0.2 3.3 GO:0070822 Sin3-type complex(GO:0070822)
0.1 0.8 GO:0090543 Flemming body(GO:0090543)
0.1 3.4 GO:0001533 cornified envelope(GO:0001533)
0.1 0.4 GO:0044609 DBIRD complex(GO:0044609)
0.1 2.0 GO:0043194 axon initial segment(GO:0043194)
0.1 7.8 GO:0005871 kinesin complex(GO:0005871)
0.1 1.9 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 0.5 GO:0031501 mannosyltransferase complex(GO:0031501)
0.1 2.7 GO:0031941 filamentous actin(GO:0031941)
0.1 5.7 GO:0005884 actin filament(GO:0005884)
0.1 0.4 GO:0043159 acrosomal matrix(GO:0043159) oxoglutarate dehydrogenase complex(GO:0045252)
0.1 29.1 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.1 1.2 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 1.4 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1 4.0 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 1.0 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 70.9 GO:0005615 extracellular space(GO:0005615)
0.1 2.6 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 5.5 GO:0005912 adherens junction(GO:0005912)
0.0 14.0 GO:0016607 nuclear speck(GO:0016607)
0.0 2.4 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 4.6 GO:0001650 fibrillar center(GO:0001650)
0.0 2.4 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 4.7 GO:0030426 growth cone(GO:0030426)
0.0 4.9 GO:0055037 recycling endosome(GO:0055037)
0.0 3.0 GO:0031012 extracellular matrix(GO:0031012)
0.0 1.7 GO:0035097 histone methyltransferase complex(GO:0035097)
0.0 1.3 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 1.0 GO:0035869 ciliary transition zone(GO:0035869)
0.0 0.5 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 2.7 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 6.9 GO:0045177 apical part of cell(GO:0045177)
0.0 0.6 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.1 GO:1990246 uniplex complex(GO:1990246)
0.0 4.3 GO:0005911 cell-cell junction(GO:0005911)
0.0 12.4 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 12.3 GO:0005783 endoplasmic reticulum(GO:0005783)
0.0 3.0 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.1 GO:0042587 glycogen granule(GO:0042587)
0.0 3.2 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.6 GO:0072686 mitotic spindle(GO:0072686)
0.0 7.6 GO:0005730 nucleolus(GO:0005730)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.2 9.6 GO:0031752 D5 dopamine receptor binding(GO:0031752)
3.0 9.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
2.4 23.7 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
2.2 15.2 GO:0061133 endopeptidase activator activity(GO:0061133)
2.0 16.2 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
1.9 9.5 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
1.8 20.1 GO:0008131 primary amine oxidase activity(GO:0008131)
1.8 7.2 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733)
1.7 5.2 GO:0004359 glutaminase activity(GO:0004359)
1.7 6.9 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
1.6 12.7 GO:0035374 chondroitin sulfate binding(GO:0035374)
1.6 4.7 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
1.5 4.4 GO:0035939 microsatellite binding(GO:0035939)
1.3 17.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
1.3 13.3 GO:1990239 steroid hormone binding(GO:1990239)
1.3 5.0 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
1.2 4.8 GO:0048408 epidermal growth factor binding(GO:0048408)
1.2 16.8 GO:0048407 platelet-derived growth factor binding(GO:0048407)
1.2 10.7 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
1.2 11.5 GO:0051959 dynein light intermediate chain binding(GO:0051959)
1.1 6.9 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
1.1 5.6 GO:0004008 copper-exporting ATPase activity(GO:0004008) copper-dependent protein binding(GO:0032767) copper-transporting ATPase activity(GO:0043682)
1.0 4.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
1.0 10.9 GO:0039706 co-receptor binding(GO:0039706)
1.0 6.9 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
1.0 3.9 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.9 2.8 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.9 4.4 GO:0046923 ER retention sequence binding(GO:0046923)
0.9 2.6 GO:0030626 U12 snRNA binding(GO:0030626)
0.8 3.3 GO:0051380 norepinephrine binding(GO:0051380)
0.7 3.6 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.7 12.0 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.7 2.1 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.7 2.7 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.7 8.6 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.6 5.2 GO:0004966 galanin receptor activity(GO:0004966)
0.6 7.7 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.6 1.9 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.6 13.7 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.6 2.9 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.5 8.6 GO:0035497 cAMP response element binding(GO:0035497)
0.5 18.0 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.5 6.2 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.5 2.0 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.5 2.0 GO:0036004 GAF domain binding(GO:0036004)
0.5 4.8 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.4 2.2 GO:0097322 7SK snRNA binding(GO:0097322)
0.4 3.0 GO:0043426 MRF binding(GO:0043426)
0.4 5.1 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.4 34.7 GO:0005518 collagen binding(GO:0005518)
0.4 3.6 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.4 5.4 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.4 5.8 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.4 2.2 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.4 10.8 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.3 40.5 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.3 1.3 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.3 2.3 GO:0045545 syndecan binding(GO:0045545)
0.3 4.6 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.3 16.7 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.3 2.9 GO:0030957 Tat protein binding(GO:0030957)
0.3 7.2 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.3 3.1 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.3 3.2 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.3 3.0 GO:0015245 fatty acid transporter activity(GO:0015245)
0.3 1.3 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.2 5.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.2 3.5 GO:0043522 leucine zipper domain binding(GO:0043522)
0.2 4.2 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.2 5.5 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.2 4.7 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.2 3.0 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.2 2.1 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.2 2.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.2 5.3 GO:0001223 transcription coactivator binding(GO:0001223)
0.2 1.6 GO:0071253 connexin binding(GO:0071253)
0.2 1.1 GO:0034452 dynactin binding(GO:0034452)
0.2 2.0 GO:0031432 titin binding(GO:0031432)
0.2 3.3 GO:0004407 histone deacetylase activity(GO:0004407)
0.2 5.4 GO:0008307 structural constituent of muscle(GO:0008307)
0.2 4.3 GO:0004707 MAP kinase activity(GO:0004707)
0.2 114.0 GO:0005509 calcium ion binding(GO:0005509)
0.2 6.5 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.1 3.3 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 2.7 GO:0008171 O-methyltransferase activity(GO:0008171)
0.1 2.4 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 1.4 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.1 2.5 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.1 5.7 GO:0098531 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.1 1.8 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 0.7 GO:0048019 receptor antagonist activity(GO:0048019)
0.1 6.1 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.1 28.1 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.1 7.8 GO:0003777 microtubule motor activity(GO:0003777)
0.1 2.7 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 7.0 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 3.8 GO:0048365 Rac GTPase binding(GO:0048365)
0.1 15.6 GO:0008017 microtubule binding(GO:0008017)
0.1 2.3 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 0.7 GO:0048156 tau protein binding(GO:0048156)
0.1 1.7 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 1.6 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 0.5 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.1 1.9 GO:0036002 pre-mRNA binding(GO:0036002)
0.1 1.0 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.1 0.4 GO:0034603 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.0 0.1 GO:0015292 uniporter activity(GO:0015292)
0.0 2.7 GO:0008081 phosphoric diester hydrolase activity(GO:0008081)
0.0 4.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 3.4 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 1.6 GO:0008200 ion channel inhibitor activity(GO:0008200)
0.0 2.4 GO:0019843 rRNA binding(GO:0019843)
0.0 2.7 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 1.2 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.3 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 3.8 GO:0051015 actin filament binding(GO:0051015)
0.0 0.5 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.9 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.7 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.2 GO:0005522 profilin binding(GO:0005522)
0.0 0.9 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 18.2 PID WNT SIGNALING PATHWAY Wnt signaling network
0.6 14.8 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.6 14.7 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.6 42.7 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.5 11.4 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.5 3.6 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.5 14.9 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.4 13.2 PID BMP PATHWAY BMP receptor signaling
0.4 12.4 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.4 4.3 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.4 22.6 PID TGFBR PATHWAY TGF-beta receptor signaling
0.4 23.7 PID RHOA REG PATHWAY Regulation of RhoA activity
0.3 17.0 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.3 50.2 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.3 3.1 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.3 7.7 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.3 5.2 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.2 10.9 PID HNF3A PATHWAY FOXA1 transcription factor network
0.2 4.4 PID ARF 3PATHWAY Arf1 pathway
0.2 4.1 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.2 6.9 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.2 3.6 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.2 5.2 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.2 8.9 PID E2F PATHWAY E2F transcription factor network
0.2 2.7 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.2 5.1 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.1 32.2 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 4.0 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 2.9 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.1 2.7 PID IL27 PATHWAY IL27-mediated signaling events
0.1 4.3 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 3.4 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.1 3.1 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.1 3.0 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.1 19.8 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.1 1.9 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1 2.5 PID TELOMERASE PATHWAY Regulation of Telomerase
0.1 3.1 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.1 1.8 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.3 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.3 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.4 ST JNK MAPK PATHWAY JNK MAPK Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 13.1 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.7 19.6 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.6 5.8 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.6 6.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.6 9.5 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.6 17.2 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.6 28.9 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.5 31.7 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.5 24.3 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.5 12.6 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.3 3.1 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.3 4.8 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.3 8.9 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.3 4.8 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.3 5.2 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.3 4.3 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.3 3.6 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.2 2.9 REACTOME SIGNALING BY NOTCH2 Genes involved in Signaling by NOTCH2
0.2 3.6 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.2 5.0 REACTOME CA DEPENDENT EVENTS Genes involved in Ca-dependent events
0.2 2.9 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.2 7.0 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.2 3.6 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.2 5.4 REACTOME MYOGENESIS Genes involved in Myogenesis
0.2 7.5 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.2 16.1 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.2 13.0 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF
0.2 10.8 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.2 1.6 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.2 12.0 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.2 3.0 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1 14.7 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 3.3 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.1 16.7 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 6.0 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.1 2.5 REACTOME EXTRACELLULAR MATRIX ORGANIZATION Genes involved in Extracellular matrix organization
0.1 1.4 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 2.1 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 1.3 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.1 2.0 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.1 1.0 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 1.4 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.1 3.8 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 8.4 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 2.6 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 2.5 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.4 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.2 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions