ISMARA results: Zbtb16

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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Zbtb16

Z-value: 1.10

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Transcription factors associated with Zbtb16

Gene Symbol	Gene ID	Gene Info
Zbtb16 NCBI RGD Ensembl	ENSRNOG00000029980	zinc finger and BTB domain containing 16

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Zbtb16	rn6_v1_chr8_-_53146953_53146953	-0.31	2.1e-08	Click!

Activity profile of Zbtb16 motif

Sorted Z-values of Zbtb16 motif

Top targets:

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Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr4_-_163762434 Show fit	56.70	ENSRNOT00000081854	Ly49si1 NCBI RGD Ensembl Show fit	immunoreceptor Ly49si1
chr4_-_164051812 Show fit	56.01	ENSRNOT00000085719	AABR07062183.1 NCBI RGD Ensembl Show fit
chr10_-_85947938 Show fit	35.57	ENSRNOT00000037318 ENSRNOT00000082427	Arl5c NCBI RGD Ensembl Show fit	ADP-ribosylation factor like GTPase 5C
chr4_-_163954817 Show fit	35.41	ENSRNOT00000079951	Ly49si3 NCBI RGD Ensembl Show fit	immunoreceptor Ly49si3
chr4_-_164015365 Show fit	33.84	ENSRNOT00000078121	Ly49si2 NCBI RGD Ensembl Show fit	immunoreceptor Ly49si2
chr20_+_3875706 Show fit	33.81	ENSRNOT00000036900	RT1-Ha NCBI RGD Ensembl Show fit	RT1 class II, locus Ha
chr4_-_163849618 Show fit	33.38	ENSRNOT00000086363 ENSRNOT00000077637	Ly49si1 NCBI RGD Ensembl Show fit	immunoreceptor Ly49si1
chr17_+_43633675 Show fit	32.11	ENSRNOT00000072119	LOC102549173 NCBI RGD Ensembl Show fit	histone H3.2-like
chr4_-_163810403 Show fit	31.84	ENSRNOT00000079704	AABR07062170.1 NCBI RGD Ensembl Show fit
chr20_-_1878126 Show fit	31.83	ENSRNOT00000000995	Ubd NCBI RGD Ensembl Show fit	ubiquitin D

Showing 1 to 10 of 200 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of Zbtb16

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
3.7	41.1	GO:0046642	negative regulation of alpha-beta T cell proliferation(GO:0046642)
1.1	36.0	GO:0035025	positive regulation of Rho protein signal transduction(GO:0035025)
1.9	33.8	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.3	32.1	GO:0006334	nucleosome assembly(GO:0006334)
4.0	31.8	GO:0070842	aggresome assembly(GO:0070842)
0.1	27.5	GO:0007264	small GTPase mediated signal transduction(GO:0007264)
7.3	22.0	GO:1903919	protein processing in phagocytic vesicle(GO:1900756) regulation of actin filament severing(GO:1903918) negative regulation of actin filament severing(GO:1903919) regulation of protein processing in phagocytic vesicle(GO:1903921) positive regulation of protein processing in phagocytic vesicle(GO:1903923)
0.2	20.9	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
5.1	20.5	GO:0051142	regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.4	18.9	GO:0050853	B cell receptor signaling pathway(GO:0050853)

Showing 1 to 10 of 167 entries

Gene overrepresentation in cellular component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	70.9	GO:0016021	integral component of membrane(GO:0016021)
0.1	44.4	GO:0009897	external side of plasma membrane(GO:0009897)
2.1	33.8	GO:0042613	MHC class II protein complex(GO:0042613)
0.3	32.1	GO:0000786	nucleosome(GO:0000786)
0.6	31.8	GO:0016235	aggresome(GO:0016235)
5.5	22.0	GO:0097513	myosin II filament(GO:0097513)
1.1	20.7	GO:0005639	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.1	20.5	GO:0005903	brush border(GO:0005903)
0.2	19.0	GO:0005814	centriole(GO:0005814)
4.7	18.9	GO:0019815	B cell receptor complex(GO:0019815)

Showing 1 to 10 of 103 entries

Gene overrepresentation in molecular function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.5	136.3	GO:0030246	carbohydrate binding(GO:0030246)
0.2	40.8	GO:0042393	histone binding(GO:0042393)
4.7	37.3	GO:0070087	chromo shadow domain binding(GO:0070087)
0.9	33.8	GO:0042605	peptide antigen binding(GO:0042605)
1.7	31.8	GO:0070628	proteasome binding(GO:0070628)
1.9	30.6	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1	28.6	GO:0005525	GTP binding(GO:0005525)
0.1	27.5	GO:0003735	structural constituent of ribosome(GO:0003735)
0.6	22.2	GO:0004532	exoribonuclease activity(GO:0004532)
7.3	22.0	GO:0031762	follicle-stimulating hormone receptor binding(GO:0031762)

Showing 1 to 10 of 127 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.8	32.3	PID IL23 PATHWAY	IL23-mediated signaling events
0.3	17.3	PID BCR 5PATHWAY	BCR signaling pathway
0.4	16.4	PID AURORA A PATHWAY	Aurora A signaling
0.7	12.5	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.3	11.4	PID TCPTP PATHWAY	Signaling events mediated by TCPTP
0.2	10.9	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.3	10.6	PID NECTIN PATHWAY	Nectin adhesion pathway
0.2	9.8	PID PLK1 PATHWAY	PLK1 signaling events
0.9	9.7	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.3	8.2	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.

Showing 1 to 10 of 33 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.7	49.4	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
0.3	49.0	REACTOME G ALPHA Q SIGNALLING EVENTS	Genes involved in G alpha (q) signalling events
0.7	25.5	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
1.7	21.7	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
2.1	18.8	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.4	18.3	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.6	17.8	REACTOME KINESINS	Genes involved in Kinesins
0.8	17.7	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.4	17.2	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.3	16.6	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling

Showing 1 to 10 of 57 entries

Results for Zbtb16

Z-value: 1.10

Motif logo

Transcription factors associated with Zbtb16

Activity-expression correlation:

Activity profile of Zbtb16 motif

Sorted Z-values of Zbtb16 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of Zbtb16

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: