ISMARA results: Ybx1_Nfya_Nfyb_Nfyc

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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Ybx1_Nfya_Nfyb_Nfyc_Cebpz

Z-value: 4.86

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Transcription factors associated with Ybx1_Nfya_Nfyb_Nfyc_Cebpz

Gene Symbol	Gene ID	Gene Info
Ybx1 NCBI RGD Ensembl	ENSRNOG00000023786	Y box binding protein 1
Nfya NCBI RGD Ensembl	ENSRNOG00000012702	nuclear transcription factor Y subunit alpha
Nfyb NCBI RGD Ensembl	ENSRNOG00000010309	nuclear transcription factor Y subunit beta
Nfyc NCBI RGD Ensembl	ENSRNOG00000010735	nuclear transcription factor Y subunit gamma
Cebpz NCBI RGD Ensembl	ENSRNOG00000005087	CCAAT/enhancer binding protein zeta

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Nfya	rn6_v1_chr9_+_14551758_14551758	0.49	7.6e-21	Click!
Cebpz	rn6_v1_chr6_-_1534488_1534488	0.39	6.9e-13	Click!
Nfyc	rn6_v1_chr5_-_139748489_139748489	0.22	9.1e-05	Click!
Nfyb	rn6_v1_chr7_+_27089278_27089278	0.22	1.0e-04	Click!
Ybx1	rn6_v1_chr5_-_138336475_138336475	0.15	5.7e-03	Click!

Activity profile of Ybx1_Nfya_Nfyb_Nfyc_Cebpz motif

Sorted Z-values of Ybx1_Nfya_Nfyb_Nfyc_Cebpz motif

Top targets:

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr17_+_43423111 Show fit	272.02	ENSRNOT00000022630	Hist1h2ba NCBI RGD Ensembl Show fit	histone cluster 1 H2B family member a
chr17_-_43422846 Show fit	258.55	ENSRNOT00000050526	Hist1h2aa NCBI RGD Ensembl Show fit	histone cluster 1 H2A family member a
chr4_+_157348020 Show fit	249.01	ENSRNOT00000020803	Cdca3 NCBI RGD Ensembl Show fit	cell division cycle associated 3
chr2_-_112831476 Show fit	240.97	ENSRNOT00000018055	Ect2 NCBI RGD Ensembl Show fit	epithelial cell transforming 2
chr19_+_25077918 Show fit	218.77	ENSRNOT00000006964	Asf1b NCBI RGD Ensembl Show fit	anti-silencing function 1B histone chaperone
chr10_-_74413745 Show fit	198.03	ENSRNOT00000038296	Prr11 NCBI RGD Ensembl Show fit	proline rich 11
chr10_-_86932154 Show fit	187.53	ENSRNOT00000085344	Top2a NCBI RGD Ensembl Show fit	topoisomerase (DNA) II alpha
chr13_+_56546021 Show fit	186.28	ENSRNOT00000016797	Aspm NCBI RGD Ensembl Show fit	abnormal spindle microtubule assembly
chr16_-_36080191 Show fit	181.93	ENSRNOT00000017635	Hmgb2l1 NCBI RGD Ensembl Show fit	high mobility group box 2-like 1
chr8_+_48665652 Show fit	156.21	ENSRNOT00000059715	H2afx NCBI RGD Ensembl Show fit	H2A histone family, member X
chr15_+_23553128 Show fit	142.43	ENSRNOT00000012985	Cdkn3 NCBI RGD Ensembl Show fit	cyclin-dependent kinase inhibitor 3
chr13_+_110511668 Show fit	137.92	ENSRNOT00000006235	Nek2 NCBI RGD Ensembl Show fit	NIMA-related kinase 2
chr3_+_111422267 Show fit	136.70	ENSRNOT00000052312	Nusap1 NCBI RGD Ensembl Show fit	nucleolar and spindle associated protein 1
chr17_-_43627629 Show fit	136.57	ENSRNOT00000022965	Hist1h2af NCBI RGD Ensembl Show fit	histone cluster 1, H2af
chr13_-_108178609 Show fit	134.89	ENSRNOT00000004525	Cenpf NCBI RGD Ensembl Show fit	centromere protein F
chr3_-_120404910 Show fit	130.59	ENSRNOT00000051783	Bub1 NCBI RGD Ensembl Show fit	BUB1 mitotic checkpoint serine/threonine kinase
chr17_-_13593423 Show fit	128.93	ENSRNOT00000019234	Cks2 NCBI RGD Ensembl Show fit	CDC28 protein kinase regulatory subunit 2
chr8_+_91368430 Show fit	123.40	ENSRNOT00000051612	Ttk NCBI RGD Ensembl Show fit	Ttk protein kinase
chr3_-_111422203 Show fit	123.06	ENSRNOT00000084290	Oip5 NCBI RGD Ensembl Show fit	Opa interacting protein 5
chr17_+_43627930 Show fit	123.04	ENSRNOT00000081719	LOC102549061 NCBI RGD Ensembl Show fit	histone H2B type 1-N-like
chr6_-_27080856 Show fit	120.14	ENSRNOT00000012512	Cenpa NCBI RGD Ensembl Show fit	centromere protein A
chr10_-_13619935 Show fit	118.63	ENSRNOT00000064392	Ccnf NCBI RGD Ensembl Show fit	cyclin F
chr10_-_91027465 Show fit	116.38	ENSRNOT00000032339	Kif18b NCBI RGD Ensembl Show fit	kinesin family member 18B
chr10_-_91027731 Show fit	115.13	ENSRNOT00000084128 ENSRNOT00000093704	Kif18b NCBI RGD Ensembl Show fit	kinesin family member 18B
chr10_-_25890639 Show fit	113.96	ENSRNOT00000085499	Hmmr NCBI RGD Ensembl Show fit	hyaluronan-mediated motility receptor
chr2_+_198388809 Show fit	111.25	ENSRNOT00000083087	Hist2h2aa3 NCBI RGD Ensembl Show fit	histone cluster 2, H2aa3
chr2_-_198382190 Show fit	109.74	ENSRNOT00000044268	Hist2h2aa2 NCBI RGD Ensembl Show fit	histone cluster 2, H2aa2
chr8_+_91368111 Show fit	109.47	ENSRNOT00000083151	Ttk NCBI RGD Ensembl Show fit	Ttk protein kinase
chr1_+_141391262 Show fit	104.73	ENSRNOT00000031783	Ticrr NCBI RGD Ensembl Show fit	TOPBP1-interacting checkpoint and replication regulator
chr8_+_71514281 Show fit	100.31	ENSRNOT00000022256	Ns5atp9 NCBI RGD Ensembl Show fit	NS5A (hepatitis C virus) transactivated protein 9
chr17_+_43633675 Show fit	100.16	ENSRNOT00000072119	LOC102549173 NCBI RGD Ensembl Show fit	histone H3.2-like
chr5_-_142933526 Show fit	95.96	ENSRNOT00000048293	Cdca8 NCBI RGD Ensembl Show fit	cell division cycle associated 8
chr20_+_20576377 Show fit	93.99	ENSRNOT00000000783 ENSRNOT00000086806	Cdk1 NCBI RGD Ensembl Show fit	cyclin-dependent kinase 1
chr10_-_45297385 Show fit	93.03	ENSRNOT00000041187	Hist3h2bb NCBI RGD Ensembl Show fit	histone cluster 3 H2B family member b
chr17_+_44528125 Show fit	91.85	ENSRNOT00000084538	LOC680322 NCBI RGD Ensembl Show fit	similar to Histone H2A type 1
chr17_-_44758170 Show fit	90.50	ENSRNOT00000091176	Hist1h2bo NCBI RGD Ensembl Show fit	histone cluster 1 H2B family member o
chr3_-_91217491 Show fit	86.28	ENSRNOT00000006115	Rag1 NCBI RGD Ensembl Show fit	recombination activating 1
chr2_+_198359754 Show fit	85.77	ENSRNOT00000048582	Hist2h2ab NCBI RGD Ensembl Show fit	histone cluster 2 H2A family member b
chr17_-_44748188 Show fit	85.76	ENSRNOT00000081970	LOC103690190 NCBI RGD Ensembl Show fit	histone H2A type 1-E
chr15_+_83442144 Show fit	85.12	ENSRNOT00000039344	Bora NCBI RGD Ensembl Show fit	bora, aurora kinase A activator
chr15_-_44411004 Show fit	85.04	ENSRNOT00000031163	Cdca2 NCBI RGD Ensembl Show fit	cell division cycle associated 2
chr10_+_45289741 Show fit	84.42	ENSRNOT00000066190	Hist3h2ba NCBI RGD Ensembl Show fit	histone cluster 3, H2ba
chr5_-_137265015 Show fit	83.75	ENSRNOT00000036151	Cdc20 NCBI RGD Ensembl Show fit	cell division cycle 20
chr17_+_43616247 Show fit	82.00	ENSRNOT00000072019	Hist1h3a NCBI RGD Ensembl Show fit	histone cluster 1, H3a
chr10_+_55626741 Show fit	80.36	ENSRNOT00000008492	Aurkb NCBI RGD Ensembl Show fit	aurora kinase B
chr2_-_30791221 Show fit	80.23	ENSRNOT00000082846	Ccnb1 NCBI RGD Ensembl Show fit	cyclin B1
chr2_+_198390166 Show fit	79.55	ENSRNOT00000081042	Hist2h3c2 NCBI RGD Ensembl Show fit	histone cluster 2, H3c2
chr7_+_140758615 Show fit	77.29	ENSRNOT00000089448	Troap NCBI RGD Ensembl Show fit	trophinin associated protein
chr10_-_29026002 Show fit	76.75	ENSRNOT00000005070	Pttg1 NCBI RGD Ensembl Show fit	pituitary tumor-transforming 1
chr3_+_148327965 Show fit	73.98	ENSRNOT00000010851 ENSRNOT00000088481	Tpx2 NCBI RGD Ensembl Show fit	TPX2, microtubule nucleation factor
chr17_-_44840131 Show fit	73.82	ENSRNOT00000083417	Hist1h3b NCBI RGD Ensembl Show fit	histone cluster 1, H3b
chr3_+_2591331 Show fit	72.75	ENSRNOT00000017466	Sapcd2 NCBI RGD Ensembl Show fit	suppressor APC domain containing 2
chr3_+_161236898 Show fit	72.68	ENSRNOT00000082303 ENSRNOT00000020323	Ube2c NCBI RGD Ensembl Show fit	ubiquitin-conjugating enzyme E2C
chr1_+_256035866 Show fit	72.12	ENSRNOT00000079726	Kif11 NCBI RGD Ensembl Show fit	kinesin family member 11
chr3_-_121822436 Show fit	71.95	ENSRNOT00000039794	Ckap2l NCBI RGD Ensembl Show fit	cytoskeleton associated protein 2-like
chr17_+_44520537 Show fit	71.70	ENSRNOT00000077985	hist1h2ail2 NCBI RGD Ensembl Show fit	histone cluster 1, H2ai-like2
chr12_-_22138382 Show fit	71.69	ENSRNOT00000001899	Lrch4 NCBI RGD Ensembl Show fit	leucine rich repeats and calponin homology domain containing 4
chr17_-_44527801 Show fit	71.14	ENSRNOT00000089643	Hist1h2bk NCBI RGD Ensembl Show fit	histone cluster 1 H2B family member k
chr18_+_27424328 Show fit	69.83	ENSRNOT00000033784	Kif20a NCBI RGD Ensembl Show fit	kinesin family member 20A
chr17_-_43614844 Show fit	69.27	ENSRNOT00000023054	Hist1h1a NCBI RGD Ensembl Show fit	histone cluster 1 H1 family member a
chr17_+_42302540 Show fit	67.96	ENSRNOT00000025389	Gmnn NCBI RGD Ensembl Show fit	geminin, DNA replication inhibitor
chr19_-_10360310 Show fit	67.91	ENSRNOT00000087100	Katnb1 NCBI RGD Ensembl Show fit	katanin regulatory subunit B1
chr17_-_43776460 Show fit	67.82	ENSRNOT00000089055	Hist2h3c2 NCBI RGD Ensembl Show fit	histone cluster 2, H3c2
chr2_+_198418691 Show fit	67.53	ENSRNOT00000089409	Hist1h2bk NCBI RGD Ensembl Show fit	histone cluster 1, H2bk
chr17_+_44758460 Show fit	66.92	ENSRNOT00000089436	Hist1h2an NCBI RGD Ensembl Show fit	histone cluster 1, H2an
chr15_-_42518855 Show fit	66.73	ENSRNOT00000076451	Esco2 NCBI RGD Ensembl Show fit	establishment of sister chromatid cohesion N-acetyltransferase 2
chr4_-_118472179 Show fit	65.96	ENSRNOT00000023856	Mxd1 NCBI RGD Ensembl Show fit	max dimerization protein 1
chr15_+_34296922 Show fit	65.70	ENSRNOT00000026430	Rec8 NCBI RGD Ensembl Show fit	REC8 meiotic recombination protein
chr9_-_10757954 Show fit	64.71	ENSRNOT00000075265	Uhrf1 NCBI RGD Ensembl Show fit	ubiquitin-like with PHD and ring finger domains 1
chr2_-_198360678 Show fit	64.56	ENSRNOT00000051917	Hist2h2ac NCBI RGD Ensembl Show fit	histone cluster 2 H2A family member c
chr9_-_10757720 Show fit	64.00	ENSRNOT00000083848	Uhrf1 NCBI RGD Ensembl Show fit	ubiquitin-like with PHD and ring finger domains 1
chr5_-_57845509 Show fit	63.64	ENSRNOT00000035541	Kif24 NCBI RGD Ensembl Show fit	kinesin family member 24
chr2_-_198380836 Show fit	63.45	ENSRNOT00000040906	LOC102548682 NCBI RGD Ensembl Show fit	histone H4-like
chr17_+_43632397 Show fit	63.19	ENSRNOT00000013790	Hist1h2ah NCBI RGD Ensembl Show fit	histone cluster 1, H2ah
chr2_+_34312766 Show fit	62.75	ENSRNOT00000060962	Cenpk NCBI RGD Ensembl Show fit	centromere protein K
chr17_+_44748482 Show fit	62.69	ENSRNOT00000083765	Hist1h2bl NCBI RGD Ensembl Show fit	histone cluster 1 H2B family member l
chr1_+_192115966 Show fit	62.49	ENSRNOT00000025629	Plk1 NCBI RGD Ensembl Show fit	polo-like kinase 1
chr17_+_44794130 Show fit	62.39	ENSRNOT00000077571	Hist1h2ac NCBI RGD Ensembl Show fit	histone cluster 1, H2ac
chr17_-_43815183 Show fit	62.17	ENSRNOT00000073188	Hist1h2ail1 NCBI RGD Ensembl Show fit	histone cluster 1, H2ai-like1
chr10_+_56546710 Show fit	62.06	ENSRNOT00000023003	Ybx2 NCBI RGD Ensembl Show fit	Y box binding protein 2
chr2_-_123282214 Show fit	61.84	ENSRNOT00000021156	Ccna2 NCBI RGD Ensembl Show fit	cyclin A2
chr7_-_141307233 Show fit	61.83	ENSRNOT00000071885	Racgap1 NCBI RGD Ensembl Show fit	Rac GTPase-activating protein 1
chr9_+_64898459 Show fit	61.56	ENSRNOT00000029526	Sgo2 NCBI RGD Ensembl Show fit	shugoshin 2
chr17_+_44738643 Show fit	61.29	ENSRNOT00000087643	LOC100910554 NCBI RGD Ensembl Show fit	histone H2A type 1-like
chr17_-_44520240 Show fit	60.94	ENSRNOT00000086538	Hist1h2bh NCBI RGD Ensembl Show fit	histone cluster 1 H2B family member h
chr9_+_98279022 Show fit	60.43	ENSRNOT00000038536	Rbm44 NCBI RGD Ensembl Show fit	RNA binding motif protein 44
chr17_+_43791657 Show fit	60.37	ENSRNOT00000074024	Hist2h3c2 NCBI RGD Ensembl Show fit	histone cluster 2, H3c2
chr17_-_43626538 Show fit	59.97	ENSRNOT00000074292	Hist2h3c2 NCBI RGD Ensembl Show fit	histone cluster 2, H3c2
chr20_+_5509059 Show fit	59.60	ENSRNOT00000065349	Kifc1 NCBI RGD Ensembl Show fit	kinesin family member C1
chr17_-_43798383 Show fit	59.35	ENSRNOT00000075069	LOC684828 NCBI RGD Ensembl Show fit	similar to Histone H1.2 (H1 VAR.1) (H1c)
chr12_-_46494174 Show fit	59.14	ENSRNOT00000086716	Cit NCBI RGD Ensembl Show fit	citron rho-interacting serine/threonine kinase
chr1_-_265798167 Show fit	58.63	ENSRNOT00000079483	Ldb1 NCBI RGD Ensembl Show fit	LIM domain binding 1
chr10_+_74413989 Show fit	57.40	ENSRNOT00000036098	Ska2 NCBI RGD Ensembl Show fit	spindle and kinetochore associated complex subunit 2
chr4_-_157798868 Show fit	57.30	ENSRNOT00000044425	Tuba3b NCBI RGD Ensembl Show fit	tubulin, alpha 3B
chr3_-_46457201 Show fit	56.80	ENSRNOT00000010683	Ly75 NCBI RGD Ensembl Show fit	lymphocyte antigen 75
chr4_-_115015965 Show fit	56.75	ENSRNOT00000014603	Mthfd2 NCBI RGD Ensembl Show fit	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
chr9_+_40972089 Show fit	54.98	ENSRNOT00000067928	Ptpn18 NCBI RGD Ensembl Show fit	protein tyrosine phosphatase, non-receptor type 18
chr10_+_29289203 Show fit	54.92	ENSRNOT00000067013	Pwwp2a NCBI RGD Ensembl Show fit	PWWP domain containing 2A
chr1_+_91663736 Show fit	54.59	ENSRNOT00000089587 ENSRNOT00000031236	Cep89 NCBI RGD Ensembl Show fit	centrosomal protein 89
chr2_-_123281856 Show fit	54.51	ENSRNOT00000079745	Ccna2 NCBI RGD Ensembl Show fit	cyclin A2
chr1_+_178039063 Show fit	54.40	ENSRNOT00000046313	Arntl NCBI RGD Ensembl Show fit	aryl hydrocarbon receptor nuclear translocator-like
chr17_+_44760056 Show fit	54.30	ENSRNOT00000052073	LOC690171 NCBI RGD Ensembl Show fit	similar to H3 histone, family 3B
chr3_-_119611136 Show fit	53.03	ENSRNOT00000016157	Ncaph NCBI RGD Ensembl Show fit	non-SMC condensin I complex, subunit H
chr17_-_43807540 Show fit	52.89	ENSRNOT00000074763	LOC684762 NCBI RGD Ensembl Show fit	similar to CG31613-PA
chr2_+_264704769 Show fit	52.87	ENSRNOT00000012667	Depdc1 NCBI RGD Ensembl Show fit	DEP domain containing 1
chr12_+_38880377 Show fit	52.48	ENSRNOT00000064390	Rhof NCBI RGD Ensembl Show fit	ras homolog family member F, filopodia associated
chr3_-_124884570 Show fit	52.40	ENSRNOT00000028887	Pcna NCBI RGD Ensembl Show fit	proliferating cell nuclear antigen
chr13_-_84452181 Show fit	51.25	ENSRNOT00000005060	Mael NCBI RGD Ensembl Show fit	maelstrom spermatogenic transposon silencer
chr10_-_85124644 Show fit	50.81	ENSRNOT00000012376	Kpnb1 NCBI RGD Ensembl Show fit	karyopherin subunit beta 1
chr9_-_26932201 Show fit	49.71	ENSRNOT00000017081	Mcm3 NCBI RGD Ensembl Show fit	minichromosome maintenance complex component 3
chr1_-_88734223 Show fit	49.28	ENSRNOT00000065011	NEWGENE_1306714 NCBI RGD Ensembl Show fit	WD repeat domain 62-like 1
chr17_-_44793927 Show fit	48.62	ENSRNOT00000086309	Hist1h2bo NCBI RGD Ensembl Show fit	histone cluster 1 H2B family member o
chr17_-_44841382 Show fit	48.25	ENSRNOT00000080119	Hist1h2ak NCBI RGD Ensembl Show fit	histone cluster 1, H2ak
chr20_+_3875706 Show fit	47.00	ENSRNOT00000036900	RT1-Ha NCBI RGD Ensembl Show fit	RT1 class II, locus Ha
chr2_-_188745144 Show fit	46.70	ENSRNOT00000055533	Cks1b NCBI RGD Ensembl Show fit	CDC28 protein kinase regulatory subunit 1B
chr3_+_100366168 Show fit	46.57	ENSRNOT00000006689	Kif18a NCBI RGD Ensembl Show fit	kinesin family member 18A
chr2_+_252263386 Show fit	46.52	ENSRNOT00000092913 ENSRNOT00000084034 ENSRNOT00000041186 ENSRNOT00000092931	Ssx2ip NCBI RGD Ensembl Show fit	SSX family member 2 interacting protein
chr17_+_44766313 Show fit	45.97	ENSRNOT00000091688	Hist1h1b NCBI RGD Ensembl Show fit	histone cluster 1 H1 family member b
chr1_-_42467586 Show fit	45.68	ENSRNOT00000029416	Fbxo5 NCBI RGD Ensembl Show fit	F-box protein 5
chr6_-_123894826 Show fit	45.40	ENSRNOT00000082444	Efcab11 NCBI RGD Ensembl Show fit	EF-hand calcium binding domain 11
chr7_+_53275676 Show fit	44.73	ENSRNOT00000031986	E2f7 NCBI RGD Ensembl Show fit	E2F transcription factor 7
chr1_-_187779675 Show fit	44.68	ENSRNOT00000024648	Arl6ip1 NCBI RGD Ensembl Show fit	ADP-ribosylation factor like GTPase 6 interacting protein 1
chr10_-_95212111 Show fit	44.57	ENSRNOT00000020795	Kpna2 NCBI RGD Ensembl Show fit	karyopherin subunit alpha 2
chr1_-_198476476 Show fit	44.56	ENSRNOT00000027525	Kif22 NCBI RGD Ensembl Show fit	kinesin family member 22
chr4_+_161685258 Show fit	44.21	ENSRNOT00000008012 ENSRNOT00000008003	Foxm1 NCBI RGD Ensembl Show fit	forkhead box M1
chr12_-_38274036 Show fit	44.18	ENSRNOT00000063990	Kntc1 NCBI RGD Ensembl Show fit	kinetochore associated 1
chr18_+_36829062 Show fit	44.11	ENSRNOT00000025467 ENSRNOT00000086979	Tcerg1 NCBI RGD Ensembl Show fit	transcription elongation regulator 1
chr17_+_43673294 Show fit	44.05	ENSRNOT00000074109	Hist2h4a NCBI RGD Ensembl Show fit	histone cluster 2, H4
chr1_-_225952516 Show fit	43.69	ENSRNOT00000043387	Incenp NCBI RGD Ensembl Show fit	inner centromere protein
chr6_+_43884678 Show fit	43.53	ENSRNOT00000091551	Rrm2 NCBI RGD Ensembl Show fit	ribonucleotide reductase regulatory subunit M2
chr1_-_81534140 Show fit	42.98	ENSRNOT00000027202	Tex101 NCBI RGD Ensembl Show fit	testis expressed 101
chr7_-_12246729 Show fit	42.81	ENSRNOT00000044030	Reep6 NCBI RGD Ensembl Show fit	receptor accessory protein 6
chr4_+_148199102 Show fit	42.72	ENSRNOT00000083563	Zfand4 NCBI RGD Ensembl Show fit	zinc finger AN1-type containing 4
chr10_-_15282951 Show fit	41.22	ENSRNOT00000027266	Rab40c NCBI RGD Ensembl Show fit	Rab40c, member RAS oncogene family
chr7_+_126736732 Show fit	41.19	ENSRNOT00000022012	Gtse1 NCBI RGD Ensembl Show fit	G-2 and S-phase expressed 1
chr14_+_10692764 Show fit	41.13	ENSRNOT00000003012	LOC100910270 NCBI RGD Ensembl Show fit	uncharacterized LOC100910270
chr7_+_143897014 Show fit	41.00	ENSRNOT00000017314	Espl1 NCBI RGD Ensembl Show fit	extra spindle pole bodies like 1, separase
chr3_+_111422435 Show fit	40.87	ENSRNOT00000081934	Nusap1 NCBI RGD Ensembl Show fit	nucleolar and spindle associated protein 1
chr8_+_79054237 Show fit	40.84	ENSRNOT00000077613	Mns1 NCBI RGD Ensembl Show fit	meiosis-specific nuclear structural 1
chr1_+_178351680 Show fit	40.72	ENSRNOT00000018532 ENSRNOT00000076925 ENSRNOT00000076430 ENSRNOT00000076756	Far1 NCBI RGD Ensembl Show fit	fatty acyl CoA reductase 1
chr7_-_120295618 Show fit	40.43	ENSRNOT00000014413	Ankrd54 NCBI RGD Ensembl Show fit	ankyrin repeat domain 54
chr14_+_108007724 Show fit	39.72	ENSRNOT00000014062	Xpo1 NCBI RGD Ensembl Show fit	exportin 1
chr4_+_127164453 Show fit	39.71	ENSRNOT00000017889	Kbtbd8 NCBI RGD Ensembl Show fit	kelch repeat and BTB domain containing 8
chr4_+_34282625 Show fit	39.42	ENSRNOT00000011138 ENSRNOT00000086735	Glcci1 NCBI RGD Ensembl Show fit	glucocorticoid induced 1
chr4_+_145282797 Show fit	39.41	ENSRNOT00000085766	Ogg1 NCBI RGD Ensembl Show fit	8-oxoguanine DNA glycosylase
chr16_+_74752655 Show fit	39.40	ENSRNOT00000029266	Ckap2 NCBI RGD Ensembl Show fit	cytoskeleton associated protein 2
chr1_-_91663467 Show fit	39.36	ENSRNOT00000033396	Faap24 NCBI RGD Ensembl Show fit	Fanconi anemia core complex associated protein 24
chr10_-_65820538 Show fit	39.29	ENSRNOT00000011808	Tmem97 NCBI RGD Ensembl Show fit	transmembrane protein 97
chr5_-_153924896 Show fit	39.22	ENSRNOT00000065247	Grhl3 NCBI RGD Ensembl Show fit	grainyhead-like transcription factor 3
chr8_+_48382121 Show fit	39.18	ENSRNOT00000008685	Thy1 NCBI RGD Ensembl Show fit	Thy-1 cell surface antigen
chrX_-_72034099 Show fit	38.63	ENSRNOT00000004310	Ercc6l NCBI RGD Ensembl Show fit	ERCC excision repair 6 like, spindle assembly checkpoint helicase
chr20_-_3419831 Show fit	38.62	ENSRNOT00000046798	Mdc1 NCBI RGD Ensembl Show fit	mediator of DNA damage checkpoint 1
chr17_-_1672021 Show fit	38.40	ENSRNOT00000036287	Zfp367 NCBI RGD Ensembl Show fit	zinc finger protein 367
chr11_+_88122271 Show fit	38.39	ENSRNOT00000002540	Sdf2l1 NCBI RGD Ensembl Show fit	stromal cell-derived factor 2-like 1
chr17_-_44738330 Show fit	38.37	ENSRNOT00000072195	LOC100364835 NCBI RGD Ensembl Show fit	histone cluster 1, H2bd-like
chr19_-_56126063 Show fit	38.25	ENSRNOT00000022658	Fanca NCBI RGD Ensembl Show fit	Fanconi anemia, complementation group A
chr10_+_103713045 Show fit	38.03	ENSRNOT00000004351	Slc9a3r1 NCBI RGD Ensembl Show fit	SLC9A3 regulator 1
chr5_-_169658875 Show fit	37.95	ENSRNOT00000015840	Kcnab2 NCBI RGD Ensembl Show fit	potassium voltage-gated channel subfamily A regulatory beta subunit 2
chr17_+_43734461 Show fit	37.78	ENSRNOT00000072564	Hist1h1d NCBI RGD Ensembl Show fit	histone cluster 1, H1d
chr5_-_147743723 Show fit	37.58	ENSRNOT00000012854	Hdac1 NCBI RGD Ensembl Show fit	histone deacetylase 1
chr4_+_179905116 Show fit	37.56	ENSRNOT00000052352	Tuba3a NCBI RGD Ensembl Show fit	tubulin, alpha 3A
chr5_-_164679654 Show fit	37.42	ENSRNOT00000035695	LOC100911456 NCBI RGD Ensembl Show fit	migration and invasion-inhibitory protein-like
chr10_-_15098791 Show fit	37.37	ENSRNOT00000026139	Chtf18 NCBI RGD Ensembl Show fit	chromosome transmission fidelity factor 18
chr1_+_190914946 Show fit	37.31	ENSRNOT00000039447	LOC691551 NCBI RGD Ensembl Show fit	similar to F28B3.5a
chr16_-_48921242 Show fit	37.06	ENSRNOT00000041596	Cenpu NCBI RGD Ensembl Show fit	centromere protein U
chr1_+_86996093 Show fit	36.97	ENSRNOT00000027425 ENSRNOT00000027494	Hnrnpl NCBI RGD Ensembl Show fit	heterogeneous nuclear ribonucleoprotein L
chr10_-_13515448 Show fit	36.75	ENSRNOT00000067660	Pdpk1 NCBI RGD Ensembl Show fit	3-phosphoinositide dependent protein kinase-1
chr1_-_214202853 Show fit	36.62	ENSRNOT00000022954	Lmntd2 NCBI RGD Ensembl Show fit	lamin tail domain containing 2
chr12_-_19314016 Show fit	36.38	ENSRNOT00000001825	Mcm7 NCBI RGD Ensembl Show fit	minichromosome maintenance complex component 7
chr5_+_24434872 Show fit	35.88	ENSRNOT00000010696	Ccne2 NCBI RGD Ensembl Show fit	cyclin E2
chr2_-_165641573 Show fit	35.80	ENSRNOT00000013987	Trim59 NCBI RGD Ensembl Show fit	tripartite motif-containing 59
chr20_+_12429315 Show fit	35.73	ENSRNOT00000001675	Pcbp3 NCBI RGD Ensembl Show fit	poly(rC) binding protein 3
chr19_-_52499433 Show fit	35.69	ENSRNOT00000021954	Cotl1 NCBI RGD Ensembl Show fit	coactosin-like F-actin binding protein 1
chr7_-_123476238 Show fit	35.49	ENSRNOT00000036917	Cenpm NCBI RGD Ensembl Show fit	centromere protein M
chr11_+_66878658 Show fit	35.36	ENSRNOT00000003208	Eaf2 NCBI RGD Ensembl Show fit	ELL associated factor 2
chr3_+_146695344 Show fit	35.32	ENSRNOT00000010955	Gins1 NCBI RGD Ensembl Show fit	GINS complex subunit 1
chr14_-_21219454 Show fit	35.31	ENSRNOT00000049462	Enam NCBI RGD Ensembl Show fit	enamelin
chr10_+_57040267 Show fit	35.24	ENSRNOT00000026207	Arrb2 NCBI RGD Ensembl Show fit	arrestin, beta 2
chr8_-_12355091 Show fit	35.08	ENSRNOT00000009318	Cep57 NCBI RGD Ensembl Show fit	centrosomal protein 57
chr10_-_62191512 Show fit	35.01	ENSRNOT00000090262	Rpa1 NCBI RGD Ensembl Show fit	replication protein A1
chr5_+_150957001 Show fit	34.89	ENSRNOT00000017549	Rpa2 NCBI RGD Ensembl Show fit	replication protein A2
chr4_+_157659147 Show fit	34.87	ENSRNOT00000048379	Iffo1 NCBI RGD Ensembl Show fit	intermediate filament family orphan 1
chr7_-_28715224 Show fit	34.80	ENSRNOT00000065899	Parpbp NCBI RGD Ensembl Show fit	PARP1 binding protein
chr19_-_27464805 Show fit	34.74	ENSRNOT00000039467	Orc6 NCBI RGD Ensembl Show fit	origin recognition complex, subunit 6
chr1_+_224939497 Show fit	34.63	ENSRNOT00000025664	Stx5 NCBI RGD Ensembl Show fit	syntaxin 5
chr1_+_72661211 Show fit	34.60	ENSRNOT00000033197	Cox6b2 NCBI RGD Ensembl Show fit	cytochrome c oxidase subunit VIb polypeptide 2
chr2_+_240396152 Show fit	34.52	ENSRNOT00000034565	Cenpe NCBI RGD Ensembl Show fit	centromere protein E
chr1_+_219078029 Show fit	34.34	ENSRNOT00000023020	Chka NCBI RGD Ensembl Show fit	choline kinase alpha
chr17_-_78812111 Show fit	34.27	ENSRNOT00000021506	Dclre1c NCBI RGD Ensembl Show fit	DNA cross-link repair 1C
chr5_+_117583502 Show fit	34.05	ENSRNOT00000010933	Usp1 NCBI RGD Ensembl Show fit	ubiquitin specific peptidase 1
chr2_+_198417619 Show fit	34.04	ENSRNOT00000085945	Hist2h3c2 NCBI RGD Ensembl Show fit	histone cluster 2, H3c2
chr17_+_44763598 Show fit	34.03	ENSRNOT00000079880	Hist1h3b NCBI RGD Ensembl Show fit	histone cluster 1, H3b
chr5_-_147761983 Show fit	33.86	ENSRNOT00000012936	Lck NCBI RGD Ensembl Show fit	LCK proto-oncogene, Src family tyrosine kinase
chr2_+_198360998 Show fit	33.83	ENSRNOT00000046129	Hist2h2be NCBI RGD Ensembl Show fit	histone cluster 2, H2be
chr15_+_33555640 Show fit	33.46	ENSRNOT00000021096	Pabpn1 NCBI RGD Ensembl Show fit	poly(A) binding protein, nuclear 1
chr4_+_69457472 Show fit	33.43	ENSRNOT00000067597	Trbv19 NCBI RGD Ensembl Show fit	T cell receptor beta, variable 19
chr14_-_6813945 Show fit	33.21	ENSRNOT00000002938	Ibsp NCBI RGD Ensembl Show fit	integrin-binding sialoprotein
chr13_+_52976507 Show fit	33.13	ENSRNOT00000090599 ENSRNOT00000011324	Kif21b NCBI RGD Ensembl Show fit	kinesin family member 21B
chr19_+_19395655 Show fit	32.82	ENSRNOT00000019130	Snx20 NCBI RGD Ensembl Show fit	sorting nexin 20
chr19_+_9668186 Show fit	32.72	ENSRNOT00000016563	Cnot1 NCBI RGD Ensembl Show fit	CCR4-NOT transcription complex, subunit 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Ybx1_Nfya_Nfyb_Nfyc_Cebpz

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
77.6	232.9	GO:1902103	metaphase/anaphase transition of meiotic cell cycle(GO:0044785) regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902102) negative regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902103) regulation of meiotic chromosome separation(GO:1905132) negative regulation of meiotic chromosome separation(GO:1905133)
46.0	137.9	GO:0030997	regulation of centriole-centriole cohesion(GO:0030997)
45.3	272.0	GO:0035093	spermatogenesis, exchange of chromosomal proteins(GO:0035093)
39.6	118.7	GO:0007079	mitotic chromosome movement towards spindle pole(GO:0007079)
37.4	224.5	GO:0090306	spindle assembly involved in meiosis(GO:0090306)
37.4	37.4	GO:0051985	negative regulation of chromosome segregation(GO:0051985)
31.3	187.5	GO:0030263	apoptotic chromosome condensation(GO:0030263)
30.8	61.6	GO:0070602	regulation of centromeric sister chromatid cohesion(GO:0070602)
30.6	183.9	GO:0090166	Golgi disassembly(GO:0090166)
29.8	208.4	GO:0000022	mitotic spindle elongation(GO:0000022) mitotic spindle midzone assembly(GO:0051256)
29.2	175.4	GO:1904668	positive regulation of ubiquitin protein ligase activity(GO:1904668)
27.6	745.8	GO:0006335	DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
27.3	109.2	GO:0002331	pre-B cell allelic exclusion(GO:0002331)
25.9	362.0	GO:0051988	regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
24.2	72.7	GO:0010993	regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
23.3	69.8	GO:0000920	cell separation after cytokinesis(GO:0000920)
22.6	45.2	GO:0071163	DNA replication preinitiation complex assembly(GO:0071163)
22.3	66.8	GO:1903165	response to polycyclic arene(GO:1903165)
21.4	128.7	GO:0030174	regulation of DNA-dependent DNA replication initiation(GO:0030174)
20.5	163.7	GO:0098532	histone H3-K27 trimethylation(GO:0098532)
20.4	20.4	GO:1990414	replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
19.8	118.6	GO:0000320	re-entry into mitotic cell cycle(GO:0000320)
19.4	116.4	GO:0071314	cellular response to cocaine(GO:0071314)
18.4	239.8	GO:0007076	mitotic chromosome condensation(GO:0007076)
18.2	181.9	GO:0006265	DNA topological change(GO:0006265)
17.9	71.6	GO:0071169	establishment of protein localization to chromatin(GO:0071169)
17.5	69.9	GO:0046985	positive regulation of hemoglobin biosynthetic process(GO:0046985)
16.7	66.7	GO:0034421	post-translational protein acetylation(GO:0034421)
16.6	1559.9	GO:0006342	chromatin silencing(GO:0006342)
16.4	82.1	GO:0046602	regulation of mitotic centrosome separation(GO:0046602)
16.3	32.5	GO:2000054	negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
16.0	1087.4	GO:0006334	nucleosome assembly(GO:0006334)
14.9	44.7	GO:0090158	endoplasmic reticulum membrane organization(GO:0090158)
14.2	28.4	GO:0032423	regulation of mismatch repair(GO:0032423)
14.0	14.0	GO:1904742	regulation of telomeric DNA binding(GO:1904742)
13.1	39.2	GO:2000298	regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
13.1	65.3	GO:0071930	negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
13.0	168.5	GO:0007063	regulation of sister chromatid cohesion(GO:0007063)
12.8	12.8	GO:0071630	nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
12.6	75.9	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
12.5	37.5	GO:0070175	positive regulation of enamel mineralization(GO:0070175)
12.0	120.1	GO:0071459	protein localization to chromosome, centromeric region(GO:0071459)
12.0	12.0	GO:1904815	negative regulation of protein localization to chromosome, telomeric region(GO:1904815)
11.8	141.1	GO:0060236	regulation of mitotic spindle organization(GO:0060236)
11.2	67.4	GO:0006287	base-excision repair, gap-filling(GO:0006287)
11.1	22.2	GO:1904781	positive regulation of protein localization to centrosome(GO:1904781)
11.1	55.4	GO:0006564	L-serine biosynthetic process(GO:0006564)
11.0	32.9	GO:1905073	occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075)
10.9	492.5	GO:0051310	metaphase plate congression(GO:0051310)
10.9	54.4	GO:2001016	positive regulation of skeletal muscle cell differentiation(GO:2001016)
10.5	10.5	GO:0000720	pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
10.4	31.2	GO:0034635	glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
10.2	30.5	GO:0060734	regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734)
10.2	61.0	GO:0002503	MHC class II protein complex assembly(GO:0002399) peptide antigen assembly with MHC class II protein complex(GO:0002503)
9.7	58.2	GO:0000056	ribosomal small subunit export from nucleus(GO:0000056)
9.7	96.9	GO:0042699	follicle-stimulating hormone signaling pathway(GO:0042699)
9.4	94.1	GO:2000271	positive regulation of fibroblast apoptotic process(GO:2000271)
9.3	157.3	GO:0034587	piRNA metabolic process(GO:0034587)
9.2	27.6	GO:0048210	Golgi vesicle fusion to target membrane(GO:0048210)
9.1	191.8	GO:0006270	DNA replication initiation(GO:0006270)
8.6	51.4	GO:0046600	negative regulation of centriole replication(GO:0046600)
8.5	25.6	GO:1904760	myofibroblast differentiation(GO:0036446) cardiac fibroblast cell differentiation(GO:0060935) cardiac fibroblast cell development(GO:0060936) epicardium-derived cardiac fibroblast cell differentiation(GO:0060938) epicardium-derived cardiac fibroblast cell development(GO:0060939) regulation of myofibroblast differentiation(GO:1904760)
8.5	25.5	GO:1901258	sensory system development(GO:0048880) cardiac cell fate determination(GO:0060913) positive regulation of granulocyte colony-stimulating factor production(GO:0071657) positive regulation of macrophage colony-stimulating factor production(GO:1901258)
8.3	33.1	GO:0007352	zygotic specification of dorsal/ventral axis(GO:0007352) positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
8.2	57.6	GO:2000348	regulation of CD40 signaling pathway(GO:2000348)
8.2	32.6	GO:1903898	negative regulation of PERK-mediated unfolded protein response(GO:1903898)
8.0	32.1	GO:0051684	maintenance of Golgi location(GO:0051684)
8.0	80.0	GO:2000042	negative regulation of double-strand break repair via homologous recombination(GO:2000042)
7.9	23.8	GO:0071245	cellular response to carbon monoxide(GO:0071245)
7.9	31.7	GO:0043570	maintenance of DNA repeat elements(GO:0043570)
7.9	118.5	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
7.8	54.9	GO:0035735	intraciliary transport involved in cilium morphogenesis(GO:0035735)
7.7	38.5	GO:0046015	regulation of transcription by glucose(GO:0046015)
7.6	60.8	GO:1902969	mitotic DNA replication(GO:1902969)
7.4	29.8	GO:0033277	abortive mitotic cell cycle(GO:0033277)
7.4	29.6	GO:0006285	base-excision repair, AP site formation(GO:0006285)
7.3	14.6	GO:1900114	positive regulation of histone H3-K9 trimethylation(GO:1900114)
7.3	29.1	GO:0090521	glomerular visceral epithelial cell migration(GO:0090521)
7.1	28.2	GO:0006369	termination of RNA polymerase II transcription(GO:0006369)
7.0	392.9	GO:0000070	mitotic sister chromatid segregation(GO:0000070)
6.9	48.1	GO:0033683	nucleotide-excision repair, DNA incision(GO:0033683)
6.9	27.5	GO:0038001	paracrine signaling(GO:0038001) TNFSF11-mediated signaling pathway(GO:0071847)
6.9	109.8	GO:0006298	mismatch repair(GO:0006298)
6.7	20.0	GO:0030578	PML body organization(GO:0030578)
6.6	26.5	GO:1904580	regulation of intracellular mRNA localization(GO:1904580)
6.6	19.9	GO:2000978	negative regulation of pro-B cell differentiation(GO:2000974) negative regulation of forebrain neuron differentiation(GO:2000978)
6.6	19.8	GO:0060066	oviduct development(GO:0060066)
6.5	13.1	GO:0000973	posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
6.5	19.4	GO:0090526	regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
6.4	70.7	GO:0060213	regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
6.4	25.7	GO:0071557	histone H3-K27 demethylation(GO:0071557)
6.4	19.2	GO:1900060	negative regulation of ceramide biosynthetic process(GO:1900060)
6.4	50.9	GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
6.4	19.1	GO:1904380	positive regulation of retrograde protein transport, ER to cytosol(GO:1904154) endoplasmic reticulum mannose trimming(GO:1904380)
6.2	18.7	GO:0019287	isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
6.2	37.0	GO:1902416	positive regulation of mRNA binding(GO:1902416)
5.9	17.8	GO:1903936	cellular response to sodium arsenite(GO:1903936)
5.9	70.8	GO:0045199	maintenance of epithelial cell apical/basal polarity(GO:0045199)
5.9	17.7	GO:0098749	cerebellar neuron development(GO:0098749)
5.6	38.9	GO:0046504	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
5.5	72.0	GO:0009396	folic acid-containing compound biosynthetic process(GO:0009396)
5.5	21.9	GO:1903334	positive regulation of protein folding(GO:1903334)
5.4	16.3	GO:0033385	geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
5.4	10.8	GO:2000612	thyroid-stimulating hormone secretion(GO:0070460) regulation of thyroid-stimulating hormone secretion(GO:2000612)
5.4	5.4	GO:0007144	female meiosis I(GO:0007144)
5.3	31.7	GO:0034773	histone H4-K20 trimethylation(GO:0034773)
5.3	21.0	GO:0038165	oncostatin-M-mediated signaling pathway(GO:0038165)
5.3	84.1	GO:0007141	male meiosis I(GO:0007141)
5.2	51.5	GO:2000781	positive regulation of double-strand break repair(GO:2000781)
5.0	15.1	GO:0035544	negative regulation of SNARE complex assembly(GO:0035544)
5.0	65.1	GO:0043968	histone H2A acetylation(GO:0043968)
4.9	24.7	GO:2000564	regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
4.9	19.7	GO:0007290	spermatid nucleus elongation(GO:0007290)
4.9	34.3	GO:0031848	protection from non-homologous end joining at telomere(GO:0031848)
4.8	38.1	GO:0042989	sequestering of actin monomers(GO:0042989)
4.7	9.5	GO:0019230	proprioception(GO:0019230)
4.7	19.0	GO:1904528	positive regulation of microtubule binding(GO:1904528)
4.7	23.6	GO:0007135	meiosis II(GO:0007135)
4.7	23.4	GO:0072615	interleukin-17 secretion(GO:0072615)
4.7	18.7	GO:0032485	regulation of Ral protein signal transduction(GO:0032485)
4.6	13.9	GO:0033566	gamma-tubulin complex localization(GO:0033566)
4.6	13.8	GO:2000410	regulation of thymocyte migration(GO:2000410)
4.6	13.7	GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
4.5	40.5	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
4.5	13.5	GO:0002378	immunoglobulin biosynthetic process(GO:0002378)
4.4	13.3	GO:0006975	DNA damage induced protein phosphorylation(GO:0006975)
4.4	13.3	GO:0046952	ketone body catabolic process(GO:0046952)
4.4	22.0	GO:0021747	cochlear nucleus development(GO:0021747)
4.4	8.8	GO:0034770	histone H4-K20 methylation(GO:0034770)
4.4	65.8	GO:1902894	negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
4.3	25.7	GO:0089700	protein kinase D signaling(GO:0089700)
4.3	21.4	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
4.3	12.8	GO:2001032	regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
4.3	17.0	GO:0070494	regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
4.2	12.7	GO:0046490	isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate metabolic process(GO:0046490)
4.2	8.3	GO:1902174	positive regulation of keratinocyte apoptotic process(GO:1902174)
4.1	24.9	GO:1900113	negative regulation of histone H3-K9 trimethylation(GO:1900113)
4.1	40.9	GO:0045588	positive regulation of gamma-delta T cell differentiation(GO:0045588) positive regulation of gamma-delta T cell activation(GO:0046645)
3.9	27.5	GO:0006868	glutamine transport(GO:0006868)
3.9	11.6	GO:0014028	notochord formation(GO:0014028)
3.8	23.1	GO:0071386	cellular response to corticosterone stimulus(GO:0071386)
3.8	15.3	GO:1903576	response to L-arginine(GO:1903576)
3.8	30.4	GO:2000270	negative regulation of fibroblast apoptotic process(GO:2000270)
3.8	22.8	GO:0030917	midbrain-hindbrain boundary development(GO:0030917)
3.8	127.6	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
3.7	48.7	GO:0000076	DNA replication checkpoint(GO:0000076)
3.7	37.0	GO:0070995	NADPH oxidation(GO:0070995)
3.6	25.4	GO:0000077	DNA damage checkpoint(GO:0000077)
3.6	25.3	GO:0043486	histone exchange(GO:0043486)
3.6	21.4	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
3.4	31.0	GO:0080009	mRNA methylation(GO:0080009)
3.4	13.7	GO:0006004	fucose metabolic process(GO:0006004)
3.4	10.2	GO:1905218	cellular response to astaxanthin(GO:1905218)
3.4	10.1	GO:0045575	basophil activation(GO:0045575)
3.4	40.3	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
3.3	43.4	GO:0070935	3'-UTR-mediated mRNA stabilization(GO:0070935)
3.3	23.3	GO:0035879	plasma membrane lactate transport(GO:0035879)
3.3	9.9	GO:0072592	oxygen metabolic process(GO:0072592)
3.3	3.3	GO:2000814	positive regulation of barbed-end actin filament capping(GO:2000814)
3.2	19.1	GO:0097411	hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
3.2	9.5	GO:0060061	regulation of collateral sprouting in absence of injury(GO:0048696) Spemann organizer formation(GO:0060061) canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation(GO:1904954)
3.2	31.6	GO:0014029	neural crest formation(GO:0014029)
3.2	25.3	GO:0001787	natural killer cell proliferation(GO:0001787)
3.1	47.1	GO:0032688	negative regulation of interferon-beta production(GO:0032688)
3.1	9.4	GO:0036378	calcitriol biosynthetic process from calciol(GO:0036378)
3.1	12.5	GO:0021775	smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
3.1	34.1	GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
3.1	12.3	GO:0034240	negative regulation of macrophage fusion(GO:0034240)
3.1	9.3	GO:0033861	negative regulation of NAD(P)H oxidase activity(GO:0033861)
3.1	18.4	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
3.1	39.9	GO:0016973	poly(A)+ mRNA export from nucleus(GO:0016973)
3.1	36.7	GO:1990416	cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
3.0	9.1	GO:1902303	negative regulation of potassium ion export(GO:1902303)
3.0	33.5	GO:0061029	eyelid development in camera-type eye(GO:0061029)
3.0	9.0	GO:1901740	negative regulation of myoblast fusion(GO:1901740)
3.0	12.0	GO:0006517	protein deglycosylation(GO:0006517)
3.0	14.9	GO:0009052	pentose-phosphate shunt, non-oxidative branch(GO:0009052)
3.0	8.9	GO:1902211	regulation of prolactin signaling pathway(GO:1902211)
3.0	8.9	GO:0071895	odontoblast differentiation(GO:0071895)
2.9	8.8	GO:0006933	negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
2.9	35.3	GO:0001833	inner cell mass cell proliferation(GO:0001833)
2.9	8.8	GO:0010265	SCF complex assembly(GO:0010265)
2.9	23.4	GO:0007131	reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
2.9	26.1	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
2.9	2.9	GO:2001271	regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
2.9	11.5	GO:0048619	embryonic hindgut morphogenesis(GO:0048619)
2.9	11.5	GO:0051572	negative regulation of histone H3-K4 methylation(GO:0051572)
2.9	22.9	GO:0043353	enucleate erythrocyte differentiation(GO:0043353)
2.7	27.3	GO:0018095	protein polyglutamylation(GO:0018095)
2.7	32.8	GO:0071712	ER-associated misfolded protein catabolic process(GO:0071712)
2.7	16.3	GO:0046836	glycolipid transport(GO:0046836)
2.7	10.8	GO:0009223	pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
2.7	10.8	GO:0007060	male meiosis chromosome segregation(GO:0007060)
2.7	5.3	GO:0031536	positive regulation of exit from mitosis(GO:0031536)
2.6	7.9	GO:0097327	response to antineoplastic agent(GO:0097327)
2.6	15.6	GO:0002913	positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
2.6	12.9	GO:0032506	cytokinetic process(GO:0032506)
2.6	5.2	GO:1903003	positive regulation of protein deubiquitination(GO:1903003) positive regulation of ubiquitin-specific protease activity(GO:2000158)
2.5	7.6	GO:0045337	farnesyl diphosphate biosynthetic process(GO:0045337)
2.5	290.7	GO:0007059	chromosome segregation(GO:0007059)
2.5	5.0	GO:0002476	antigen processing and presentation of endogenous peptide antigen via MHC class Ib(GO:0002476)
2.5	7.6	GO:0018992	germ-line sex determination(GO:0018992)
2.5	37.5	GO:0002227	innate immune response in mucosa(GO:0002227)
2.5	10.0	GO:0032802	low-density lipoprotein particle receptor catabolic process(GO:0032802) regulation of low-density lipoprotein particle receptor catabolic process(GO:0032803)
2.5	15.0	GO:0070375	ERK5 cascade(GO:0070375)
2.5	32.4	GO:0061014	positive regulation of mRNA catabolic process(GO:0061014)
2.5	2.5	GO:0043578	nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration(GO:0021817) nuclear migration along microtubule(GO:0030473) nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
2.5	4.9	GO:1900175	regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145) regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900175)
2.4	14.7	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
2.4	7.3	GO:0010986	regulation of high-density lipoprotein particle clearance(GO:0010982) positive regulation of lipoprotein particle clearance(GO:0010986)
2.4	4.9	GO:0072369	regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
2.4	19.4	GO:0048194	Golgi vesicle budding(GO:0048194)
2.4	4.8	GO:0007089	traversing start control point of mitotic cell cycle(GO:0007089)
2.4	12.0	GO:0001574	ganglioside biosynthetic process(GO:0001574)
2.4	21.5	GO:0000733	DNA strand renaturation(GO:0000733)
2.4	14.2	GO:0014053	negative regulation of gamma-aminobutyric acid secretion(GO:0014053)
2.4	16.5	GO:1904628	response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
2.3	9.4	GO:2001171	positive regulation of ATP biosynthetic process(GO:2001171)
2.3	7.0	GO:0032472	Golgi calcium ion transport(GO:0032472)
2.3	6.9	GO:0072710	response to hydroxyurea(GO:0072710) response to dithiothreitol(GO:0072720)
2.3	13.9	GO:0051490	negative regulation of filopodium assembly(GO:0051490)
2.3	36.6	GO:0048026	positive regulation of mRNA splicing, via spliceosome(GO:0048026)
2.3	4.6	GO:0000448	cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448)
2.2	15.7	GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504)
2.2	15.7	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
2.2	11.1	GO:0072366	positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter(GO:0072366)
2.2	17.7	GO:0001842	neural fold formation(GO:0001842)
2.2	6.5	GO:0060474	positive regulation of sperm motility involved in capacitation(GO:0060474)
2.2	8.6	GO:0048254	snoRNA localization(GO:0048254)
2.2	40.9	GO:0046597	negative regulation of viral entry into host cell(GO:0046597)
2.1	21.4	GO:0014807	regulation of somitogenesis(GO:0014807)
2.1	36.1	GO:0070986	left/right axis specification(GO:0070986)
2.1	8.5	GO:0010877	lipid transport involved in lipid storage(GO:0010877) positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253)
2.1	12.6	GO:1904251	regulation of bile acid metabolic process(GO:1904251)
2.1	10.4	GO:0035278	miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
2.1	16.5	GO:0010569	regulation of double-strand break repair via homologous recombination(GO:0010569)
2.0	188.3	GO:0007050	cell cycle arrest(GO:0007050)
2.0	22.2	GO:0051198	negative regulation of glycolytic process(GO:0045820) negative regulation of cofactor metabolic process(GO:0051195) negative regulation of coenzyme metabolic process(GO:0051198)
2.0	26.1	GO:0033120	positive regulation of RNA splicing(GO:0033120)
2.0	34.0	GO:0016226	iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
2.0	2.0	GO:1904054	regulation of cholangiocyte proliferation(GO:1904054) positive regulation of cholangiocyte proliferation(GO:1904056) cholangiocyte proliferation(GO:1990705)
2.0	23.4	GO:0019985	translesion synthesis(GO:0019985)
2.0	27.3	GO:0035067	negative regulation of histone acetylation(GO:0035067)
1.9	29.1	GO:0051764	actin crosslink formation(GO:0051764)
1.9	11.6	GO:0097338	response to clozapine(GO:0097338)
1.9	3.9	GO:0045578	negative regulation of B cell differentiation(GO:0045578)
1.9	1.9	GO:0036493	positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
1.9	1.9	GO:0046671	negative regulation of retinal cell programmed cell death(GO:0046671)
1.9	19.2	GO:1900363	regulation of mRNA polyadenylation(GO:1900363)
1.9	7.6	GO:0003415	chondrocyte hypertrophy(GO:0003415)
1.9	17.1	GO:0046784	viral mRNA export from host cell nucleus(GO:0046784)
1.9	1.9	GO:0072137	condensed mesenchymal cell proliferation(GO:0072137)
1.8	3.7	GO:0000212	meiotic spindle organization(GO:0000212)
1.8	1.8	GO:0030423	targeting of mRNA for destruction involved in RNA interference(GO:0030423) siRNA loading onto RISC involved in RNA interference(GO:0035087)
1.8	9.1	GO:0046485	ether lipid metabolic process(GO:0046485)
1.8	5.4	GO:0061086	negative regulation of histone H3-K27 methylation(GO:0061086)
1.8	10.8	GO:0018065	protein-cofactor linkage(GO:0018065)
1.8	3.6	GO:0097037	heme export(GO:0097037)
1.8	10.7	GO:0010360	negative regulation of anion channel activity(GO:0010360)
1.8	12.4	GO:1900017	positive regulation of cytokine production involved in inflammatory response(GO:1900017)
1.7	38.2	GO:0048255	mRNA stabilization(GO:0048255)
1.7	12.2	GO:0000395	mRNA 5'-splice site recognition(GO:0000395)
1.7	20.5	GO:0043044	ATP-dependent chromatin remodeling(GO:0043044)
1.7	13.7	GO:1904869	protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) protein localization to nucleoplasm(GO:1990173)
1.7	66.2	GO:0010501	RNA secondary structure unwinding(GO:0010501)
1.7	21.6	GO:0001973	adenosine receptor signaling pathway(GO:0001973)
1.6	26.4	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
1.6	1.6	GO:0090666	scaRNA localization to Cajal body(GO:0090666)
1.6	19.6	GO:0031468	nuclear envelope reassembly(GO:0031468)
1.6	11.4	GO:0048496	maintenance of organ identity(GO:0048496)
1.6	6.4	GO:0016240	autophagosome docking(GO:0016240)
1.6	11.2	GO:1903826	arginine transmembrane transport(GO:1903826) basic amino acid transmembrane transport(GO:1990822)
1.6	11.2	GO:0060075	regulation of resting membrane potential(GO:0060075)
1.6	9.6	GO:0000480	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
1.6	4.7	GO:0032978	protein insertion into membrane from inner side(GO:0032978)
1.6	11.0	GO:0051013	microtubule severing(GO:0051013)
1.6	26.7	GO:0050765	negative regulation of phagocytosis(GO:0050765)
1.6	7.8	GO:2000491	positive regulation of hepatic stellate cell activation(GO:2000491)
1.6	35.7	GO:0050832	defense response to fungus(GO:0050832)
1.5	17.0	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
1.5	4.6	GO:0031053	primary miRNA processing(GO:0031053)
1.5	4.6	GO:0042539	hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
1.5	7.5	GO:0030070	insulin processing(GO:0030070)
1.5	10.4	GO:0007253	cytoplasmic sequestering of NF-kappaB(GO:0007253)
1.5	5.9	GO:0060631	regulation of meiosis I(GO:0060631)
1.5	11.8	GO:0006021	inositol biosynthetic process(GO:0006021)
1.5	10.2	GO:1903376	neuron intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0036480) regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903376) negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
1.4	13.0	GO:0050779	RNA destabilization(GO:0050779)
1.4	15.9	GO:0006013	mannose metabolic process(GO:0006013)
1.4	2.9	GO:0099545	trans-synaptic signaling by trans-synaptic complex(GO:0099545)
1.4	5.8	GO:0051683	establishment of Golgi localization(GO:0051683)
1.4	21.6	GO:0050930	induction of positive chemotaxis(GO:0050930)
1.4	14.4	GO:0031284	positive regulation of guanylate cyclase activity(GO:0031284)
1.4	10.0	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
1.4	4.3	GO:0098507	polynucleotide 5' dephosphorylation(GO:0098507)
1.4	7.0	GO:0030011	maintenance of cell polarity(GO:0030011)
1.4	7.0	GO:0061621	NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
1.4	2.7	GO:0010157	response to chlorate(GO:0010157)
1.4	17.7	GO:0098719	sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
1.4	44.6	GO:0051290	protein heterotetramerization(GO:0051290)
1.3	4.0	GO:0006478	peptidyl-tyrosine sulfation(GO:0006478)
1.3	46.9	GO:0031047	gene silencing by RNA(GO:0031047)
1.3	16.0	GO:0046605	regulation of centrosome cycle(GO:0046605)
1.3	10.6	GO:0042795	snRNA transcription from RNA polymerase II promoter(GO:0042795)
1.3	21.2	GO:2001022	positive regulation of response to DNA damage stimulus(GO:2001022)
1.3	35.4	GO:0000281	mitotic cytokinesis(GO:0000281)
1.3	5.2	GO:1903564	regulation of protein localization to cilium(GO:1903564)
1.3	12.7	GO:0072526	pyridine-containing compound catabolic process(GO:0072526)
1.3	6.4	GO:1902951	negative regulation of dendritic spine maintenance(GO:1902951)
1.3	8.9	GO:2000394	positive regulation of lamellipodium morphogenesis(GO:2000394)
1.3	21.3	GO:0019532	oxalate transport(GO:0019532)
1.3	6.3	GO:0070889	platelet alpha granule organization(GO:0070889)
1.2	11.2	GO:0045162	clustering of voltage-gated sodium channels(GO:0045162)
1.2	24.6	GO:0045116	protein neddylation(GO:0045116)
1.2	3.7	GO:0060743	epithelial cell maturation involved in prostate gland development(GO:0060743)
1.2	8.6	GO:0043686	co-translational protein modification(GO:0043686)
1.2	7.3	GO:0031087	nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
1.2	2.4	GO:0072553	terminal button organization(GO:0072553)
1.2	8.4	GO:0015722	canalicular bile acid transport(GO:0015722)
1.2	19.1	GO:0006376	mRNA splice site selection(GO:0006376)
1.2	10.7	GO:0045292	mRNA cis splicing, via spliceosome(GO:0045292)
1.2	46.7	GO:0002474	antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
1.2	3.5	GO:0017198	N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
1.2	2.3	GO:2000836	positive regulation of androgen secretion(GO:2000836)
1.1	3.4	GO:2000660	negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
1.1	31.5	GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
1.1	6.7	GO:0007341	penetration of zona pellucida(GO:0007341)
1.1	5.4	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
1.1	2.1	GO:0009436	glyoxylate catabolic process(GO:0009436)
1.1	19.3	GO:0060261	positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261)
1.1	8.5	GO:2000969	positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
1.1	8.5	GO:0021979	hypothalamus cell differentiation(GO:0021979)
1.1	6.3	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
1.1	8.4	GO:0006271	DNA strand elongation involved in DNA replication(GO:0006271)
1.0	9.2	GO:0043249	erythrocyte maturation(GO:0043249)
1.0	6.1	GO:0046477	glycosylceramide catabolic process(GO:0046477)
1.0	3.1	GO:0086024	adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
1.0	7.1	GO:0048664	neuron fate determination(GO:0048664)
1.0	12.2	GO:1902857	positive regulation of nonmotile primary cilium assembly(GO:1902857)
1.0	19.3	GO:0035024	negative regulation of Rho protein signal transduction(GO:0035024)
1.0	1.9	GO:0046351	disaccharide biosynthetic process(GO:0046351)
1.0	5.8	GO:0045003	DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
1.0	4.8	GO:0035330	regulation of hippo signaling(GO:0035330)
1.0	6.7	GO:0006621	protein retention in ER lumen(GO:0006621)
0.9	0.9	GO:2000040	regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.9	12.2	GO:0045948	positive regulation of translational initiation(GO:0045948)
0.9	6.5	GO:1902474	positive regulation of protein localization to synapse(GO:1902474)
0.9	3.7	GO:0070914	UV-damage excision repair(GO:0070914)
0.9	6.5	GO:0097527	necroptotic signaling pathway(GO:0097527)
0.9	9.3	GO:0032516	positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.9	7.4	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
0.9	2.7	GO:0044752	response to human chorionic gonadotropin(GO:0044752)
0.9	5.4	GO:0060467	negative regulation of fertilization(GO:0060467)
0.9	3.6	GO:0061083	regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.9	22.6	GO:0000154	rRNA modification(GO:0000154)
0.9	0.9	GO:1903912	negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912)
0.9	18.9	GO:0060009	Sertoli cell development(GO:0060009)
0.9	0.9	GO:2000197	regulation of mRNA export from nucleus(GO:0010793) regulation of ribonucleoprotein complex localization(GO:2000197)
0.9	17.5	GO:0006198	cAMP catabolic process(GO:0006198)
0.9	14.9	GO:0015701	bicarbonate transport(GO:0015701)
0.9	4.4	GO:1900825	regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900825)
0.9	0.9	GO:0072719	cellular response to cisplatin(GO:0072719)
0.8	6.8	GO:0021942	radial glia guided migration of Purkinje cell(GO:0021942)
0.8	11.6	GO:0051601	exocyst localization(GO:0051601)
0.8	34.8	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
0.8	8.9	GO:0032237	activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.8	3.2	GO:0021571	rhombomere 5 development(GO:0021571)
0.8	1.6	GO:0006407	rRNA export from nucleus(GO:0006407)
0.8	10.3	GO:0006880	intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.8	3.9	GO:1903251	multi-ciliated epithelial cell differentiation(GO:1903251)
0.8	4.7	GO:0007099	centriole replication(GO:0007099)
0.8	13.9	GO:0036158	outer dynein arm assembly(GO:0036158)
0.8	1.5	GO:0042369	vitamin D catabolic process(GO:0042369)
0.7	0.7	GO:0070370	cellular heat acclimation(GO:0070370)
0.7	11.9	GO:0021854	hypothalamus development(GO:0021854)
0.7	11.8	GO:0001675	acrosome assembly(GO:0001675)
0.7	5.9	GO:0019852	L-ascorbic acid metabolic process(GO:0019852)
0.7	3.7	GO:1903215	negative regulation of protein targeting to mitochondrion(GO:1903215)
0.7	15.9	GO:0043153	entrainment of circadian clock by photoperiod(GO:0043153)
0.7	6.5	GO:0035608	protein deglutamylation(GO:0035608)
0.7	1.4	GO:0002424	T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840)
0.7	5.7	GO:0044829	positive regulation by host of viral genome replication(GO:0044829)
0.7	5.7	GO:0007288	sperm axoneme assembly(GO:0007288)
0.7	2.8	GO:0038203	TORC2 signaling(GO:0038203)
0.7	4.2	GO:1900242	regulation of synaptic vesicle endocytosis(GO:1900242)
0.7	1.4	GO:0036353	histone H2A-K119 monoubiquitination(GO:0036353)
0.7	1.4	GO:0036337	Fas signaling pathway(GO:0036337)
0.7	5.5	GO:0016556	mRNA modification(GO:0016556)
0.7	9.5	GO:0007256	activation of JNKK activity(GO:0007256)
0.7	2.7	GO:0051005	negative regulation of lipoprotein lipase activity(GO:0051005)
0.7	3.3	GO:0071043	CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.6	11.6	GO:0035329	hippo signaling(GO:0035329)
0.6	3.8	GO:0032392	DNA geometric change(GO:0032392)
0.6	8.9	GO:0050927	positive regulation of positive chemotaxis(GO:0050927)
0.6	0.6	GO:1900169	regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.6	2.5	GO:1904640	response to methionine(GO:1904640)
0.6	6.8	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.6	7.4	GO:0016578	histone deubiquitination(GO:0016578)
0.6	15.1	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.6	3.0	GO:1902455	negative regulation of stem cell population maintenance(GO:1902455)
0.6	3.6	GO:0032464	positive regulation of protein homooligomerization(GO:0032464)
0.6	57.1	GO:0018107	peptidyl-threonine phosphorylation(GO:0018107)
0.6	5.3	GO:0090091	positive regulation of extracellular matrix disassembly(GO:0090091)
0.6	2.4	GO:0034497	protein localization to pre-autophagosomal structure(GO:0034497)
0.6	1.2	GO:0033030	negative regulation of neutrophil apoptotic process(GO:0033030)
0.6	10.1	GO:0010165	response to X-ray(GO:0010165)
0.6	3.5	GO:0060008	Sertoli cell differentiation(GO:0060008)
0.6	29.0	GO:0043966	histone H3 acetylation(GO:0043966)
0.6	1.2	GO:0006172	ADP biosynthetic process(GO:0006172)
0.6	6.8	GO:0007250	activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.6	5.0	GO:0046827	positive regulation of protein export from nucleus(GO:0046827)
0.6	10.0	GO:0032967	positive regulation of collagen biosynthetic process(GO:0032967)
0.6	2.2	GO:0051444	negative regulation of ubiquitin-protein transferase activity(GO:0051444)
0.5	10.9	GO:0016445	somatic diversification of immunoglobulins(GO:0016445)
0.5	3.2	GO:0008616	queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.5	16.5	GO:0006405	RNA export from nucleus(GO:0006405)
0.5	4.7	GO:0045717	negative regulation of fatty acid biosynthetic process(GO:0045717)
0.5	1.6	GO:0006433	prolyl-tRNA aminoacylation(GO:0006433)
0.5	4.2	GO:0006301	postreplication repair(GO:0006301)
0.5	9.4	GO:0006378	mRNA polyadenylation(GO:0006378)
0.5	6.9	GO:1990845	adaptive thermogenesis(GO:1990845)
0.5	2.9	GO:0016255	attachment of GPI anchor to protein(GO:0016255)
0.5	8.8	GO:0016180	snRNA processing(GO:0016180)
0.5	6.3	GO:0043488	regulation of mRNA stability(GO:0043488)
0.5	13.6	GO:0000387	spliceosomal snRNP assembly(GO:0000387)
0.5	10.5	GO:0061099	negative regulation of protein tyrosine kinase activity(GO:0061099)
0.5	6.7	GO:0051016	barbed-end actin filament capping(GO:0051016)
0.5	13.9	GO:0051281	positive regulation of release of sequestered calcium ion into cytosol(GO:0051281)
0.5	21.9	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.5	5.7	GO:0071404	cellular response to low-density lipoprotein particle stimulus(GO:0071404)
0.5	4.7	GO:0070327	thyroid hormone transport(GO:0070327)
0.5	0.9	GO:0090073	positive regulation of protein homodimerization activity(GO:0090073)
0.5	1.9	GO:0006477	protein sulfation(GO:0006477)
0.5	11.6	GO:0060122	inner ear receptor stereocilium organization(GO:0060122)
0.5	13.6	GO:0010833	telomere maintenance via telomere lengthening(GO:0010833)
0.5	16.8	GO:2001238	positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.4	1.3	GO:0018199	peptidyl-glutamine modification(GO:0018199)
0.4	1.3	GO:0070681	glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.4	3.1	GO:0051457	maintenance of protein location in nucleus(GO:0051457)
0.4	70.0	GO:0006281	DNA repair(GO:0006281)
0.4	12.5	GO:0001578	microtubule bundle formation(GO:0001578)
0.4	1.3	GO:0060290	transdifferentiation(GO:0060290)
0.4	2.1	GO:0060014	granulosa cell differentiation(GO:0060014)
0.4	6.3	GO:0006656	phosphatidylcholine biosynthetic process(GO:0006656)
0.4	4.6	GO:0001522	pseudouridine synthesis(GO:0001522)
0.4	7.0	GO:0051028	mRNA transport(GO:0051028)
0.4	7.4	GO:0001502	cartilage condensation(GO:0001502)
0.4	16.4	GO:0097006	regulation of plasma lipoprotein particle levels(GO:0097006)
0.4	3.6	GO:0048280	vesicle fusion with Golgi apparatus(GO:0048280)
0.4	44.5	GO:0000209	protein polyubiquitination(GO:0000209)
0.4	1.9	GO:0016259	selenocysteine metabolic process(GO:0016259)
0.4	2.2	GO:0071569	protein ufmylation(GO:0071569)
0.4	3.3	GO:0007512	adult heart development(GO:0007512)
0.4	64.9	GO:0006397	mRNA processing(GO:0006397)
0.4	3.5	GO:0003323	type B pancreatic cell development(GO:0003323)
0.4	7.4	GO:0006998	nuclear envelope organization(GO:0006998)
0.4	8.4	GO:0030488	tRNA methylation(GO:0030488)
0.3	2.8	GO:0003351	epithelial cilium movement(GO:0003351)
0.3	1.4	GO:0021684	cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.3	1.3	GO:0070272	proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.3	1.0	GO:0001907	killing by symbiont of host cells(GO:0001907) disruption by symbiont of host cell(GO:0044004)
0.3	12.0	GO:0046513	ceramide biosynthetic process(GO:0046513)
0.3	6.0	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.3	30.0	GO:0007286	spermatid development(GO:0007286)
0.3	1.6	GO:0006553	lysine metabolic process(GO:0006553)
0.3	11.0	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.3	1.3	GO:0030299	intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856)
0.3	5.0	GO:1903432	regulation of TORC1 signaling(GO:1903432)
0.3	4.6	GO:0070897	DNA-templated transcriptional preinitiation complex assembly(GO:0070897)
0.3	1.5	GO:0010572	positive regulation of platelet activation(GO:0010572)
0.3	1.1	GO:0060054	positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.3	1.1	GO:2001199	negative regulation of dendritic cell differentiation(GO:2001199)
0.3	3.4	GO:0040034	regulation of development, heterochronic(GO:0040034)
0.3	2.0	GO:0097068	response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.3	4.4	GO:1903427	negative regulation of reactive oxygen species biosynthetic process(GO:1903427)
0.3	3.3	GO:0022615	protein to membrane docking(GO:0022615)
0.3	2.2	GO:0009162	deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.3	3.0	GO:0021692	cerebellar Purkinje cell layer morphogenesis(GO:0021692)
0.3	12.8	GO:0030317	sperm motility(GO:0030317)
0.3	1.6	GO:0001783	B cell apoptotic process(GO:0001783)
0.3	0.8	GO:1901838	positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.3	6.0	GO:0035458	cellular response to interferon-beta(GO:0035458)
0.3	2.5	GO:0002021	response to dietary excess(GO:0002021)
0.2	5.9	GO:0030866	cortical actin cytoskeleton organization(GO:0030866)
0.2	0.2	GO:0072076	nephrogenic mesenchyme development(GO:0072076)
0.2	0.5	GO:0007127	meiosis I(GO:0007127)
0.2	1.2	GO:0032825	positive regulation of natural killer cell differentiation(GO:0032825)
0.2	0.2	GO:0052490	negative regulation by symbiont of host apoptotic process(GO:0033668) negative regulation by symbiont of host programmed cell death(GO:0052041) negative regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052490)
0.2	3.6	GO:0061003	positive regulation of dendritic spine morphogenesis(GO:0061003)
0.2	0.7	GO:0010266	response to vitamin B1(GO:0010266)
0.2	55.8	GO:0000278	mitotic cell cycle(GO:0000278)
0.2	6.1	GO:2000401	regulation of lymphocyte migration(GO:2000401)
0.2	15.0	GO:0030282	bone mineralization(GO:0030282)
0.2	2.5	GO:0006491	N-glycan processing(GO:0006491)
0.2	1.4	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.2	14.6	GO:0007030	Golgi organization(GO:0007030)
0.2	3.2	GO:0001731	formation of translation preinitiation complex(GO:0001731)
0.2	1.9	GO:0006054	N-acetylneuraminate metabolic process(GO:0006054)
0.2	1.2	GO:0046208	spermine catabolic process(GO:0046208)
0.2	0.7	GO:0045218	zonula adherens maintenance(GO:0045218)
0.2	0.6	GO:0060060	post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
0.2	0.9	GO:0000066	mitochondrial ornithine transport(GO:0000066) ornithine transport(GO:0015822)
0.2	5.0	GO:0001938	positive regulation of endothelial cell proliferation(GO:0001938)
0.2	1.6	GO:0072673	lamellipodium morphogenesis(GO:0072673)
0.2	0.7	GO:1904400	response to Thyroid stimulating hormone(GO:1904400) cellular response to Thyroid stimulating hormone(GO:1904401)
0.2	1.3	GO:0090342	regulation of cell aging(GO:0090342)
0.2	5.8	GO:0015914	phospholipid transport(GO:0015914)
0.1	10.2	GO:0090630	activation of GTPase activity(GO:0090630)
0.1	1.8	GO:0035493	SNARE complex assembly(GO:0035493)
0.1	0.4	GO:0033306	phytol metabolic process(GO:0033306) fatty alcohol metabolic process(GO:1903173)
0.1	0.5	GO:0070836	caveola assembly(GO:0070836)
0.1	7.2	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.1	1.6	GO:0051225	spindle assembly(GO:0051225)
0.1	2.9	GO:0006672	ceramide metabolic process(GO:0006672)
0.1	1.1	GO:0002067	glandular epithelial cell differentiation(GO:0002067)
0.1	4.8	GO:0042273	ribosomal large subunit biogenesis(GO:0042273)
0.1	3.7	GO:1904893	negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.1	1.4	GO:1990126	retrograde transport, endosome to plasma membrane(GO:1990126)
0.1	0.8	GO:0006750	glutathione biosynthetic process(GO:0006750)
0.1	0.5	GO:0002098	tRNA wobble base modification(GO:0002097) tRNA wobble uridine modification(GO:0002098)
0.1	0.4	GO:0046641	positive regulation of alpha-beta T cell proliferation(GO:0046641)
0.1	0.7	GO:0010839	negative regulation of keratinocyte proliferation(GO:0010839)
0.1	1.1	GO:1900004	regulation of serine-type endopeptidase activity(GO:1900003) negative regulation of serine-type endopeptidase activity(GO:1900004) regulation of serine-type peptidase activity(GO:1902571) negative regulation of serine-type peptidase activity(GO:1902572)
0.1	1.8	GO:0001881	receptor recycling(GO:0001881)
0.1	0.2	GO:0015811	L-cystine transport(GO:0015811)
0.1	7.7	GO:0060271	cilium morphogenesis(GO:0060271)
0.1	0.5	GO:0070536	protein K63-linked deubiquitination(GO:0070536)
0.0	0.4	GO:0044030	regulation of DNA methylation(GO:0044030)
0.0	0.7	GO:0006783	heme biosynthetic process(GO:0006783)
0.0	2.1	GO:0018022	peptidyl-lysine methylation(GO:0018022)
0.0	0.2	GO:0050962	detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0	0.1	GO:0045076	regulation of interleukin-2 biosynthetic process(GO:0045076)
0.0	0.5	GO:0032609	interferon-gamma production(GO:0032609)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
79.4	317.8	GO:0097149	centralspindlin complex(GO:0097149)
58.1	174.2	GO:0097125	cyclin B1-CDK1 complex(GO:0097125)
48.3	193.1	GO:0000942	condensed nuclear chromosome outer kinetochore(GO:0000942)
46.9	187.5	GO:0009330	DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
46.8	140.3	GO:0097124	cyclin A2-CDK2 complex(GO:0097124)
37.3	3654.8	GO:0000786	nucleosome(GO:0000786)
29.9	179.6	GO:0032133	chromosome passenger complex(GO:0032133)
28.9	231.5	GO:0000235	astral microtubule(GO:0000235) aster(GO:0005818)
26.6	186.3	GO:0036449	microtubule minus-end(GO:0036449)
25.2	226.8	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
20.2	121.0	GO:0071547	piP-body(GO:0071547)
19.0	19.0	GO:0030981	cortical microtubule cytoskeleton(GO:0030981)
18.7	18.7	GO:1990826	nucleoplasmic periphery of the nuclear pore complex(GO:1990826)
17.5	52.4	GO:0070557	PCNA-p21 complex(GO:0070557)
16.7	83.7	GO:0000778	condensed nuclear chromosome kinetochore(GO:0000778)
14.7	44.2	GO:1990423	RZZ complex(GO:1990423)
14.6	160.4	GO:0042555	MCM complex(GO:0042555)
14.5	43.6	GO:0000811	GINS complex(GO:0000811)
14.5	43.5	GO:0033186	CAF-1 complex(GO:0033186)
14.4	28.8	GO:0005713	recombination nodule(GO:0005713)
14.3	42.8	GO:0044317	rod spherule(GO:0044317)
12.6	238.8	GO:0010369	chromocenter(GO:0010369)
11.9	190.6	GO:0042613	MHC class II protein complex(GO:0042613)
11.8	35.5	GO:0031262	Ndc80 complex(GO:0031262)
10.9	43.5	GO:0005971	ribonucleoside-diphosphate reductase complex(GO:0005971)
10.6	31.7	GO:0032301	MutSalpha complex(GO:0032301)
9.5	189.4	GO:0005680	anaphase-promoting complex(GO:0005680)
8.9	35.6	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
8.8	17.7	GO:0071546	pi-body(GO:0071546)
8.3	33.1	GO:0071144	SMAD2-SMAD3 protein complex(GO:0071144)
8.2	74.2	GO:0031616	spindle pole centrosome(GO:0031616)
8.1	120.9	GO:0005662	DNA replication factor A complex(GO:0005662)
8.0	56.3	GO:0005828	kinetochore microtubule(GO:0005828)
7.6	60.9	GO:0005964	phosphorylase kinase complex(GO:0005964)
7.6	53.0	GO:0044815	DNA packaging complex(GO:0044815)
7.2	50.7	GO:0042382	paraspeckles(GO:0042382)
7.1	262.4	GO:0005876	spindle microtubule(GO:0005876)
7.0	674.3	GO:0000776	kinetochore(GO:0000776)
7.0	13.9	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
7.0	13.9	GO:0008275	gamma-tubulin small complex(GO:0008275)
6.9	20.7	GO:0000802	transverse filament(GO:0000802)
6.9	158.2	GO:0019013	viral nucleocapsid(GO:0019013)
6.7	47.1	GO:0097136	Bcl-2 family protein complex(GO:0097136)
6.6	39.8	GO:0043203	axon hillock(GO:0043203)
6.5	19.5	GO:0002945	cyclin K-CDK12 complex(GO:0002944) cyclin K-CDK13 complex(GO:0002945)
6.3	75.6	GO:0000812	Swr1 complex(GO:0000812)
6.2	49.6	GO:0031211	serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
6.0	65.8	GO:0097539	ciliary transition fiber(GO:0097539)
6.0	41.9	GO:0070775	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
6.0	71.7	GO:0072687	meiotic spindle(GO:0072687)
5.9	29.4	GO:0008622	epsilon DNA polymerase complex(GO:0008622)
5.8	34.7	GO:0005664	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
5.7	28.7	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
5.7	28.7	GO:0071256	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
5.6	16.9	GO:0032398	MHC class Ib protein complex(GO:0032398)
5.4	86.9	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
5.4	200.2	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
5.4	32.4	GO:0030896	checkpoint clamp complex(GO:0030896)
5.3	42.7	GO:1990075	periciliary membrane compartment(GO:1990075)
5.2	31.0	GO:0036396	MIS complex(GO:0036396)
4.8	43.5	GO:0097433	dense body(GO:0097433)
4.6	18.4	GO:0099522	region of cytosol(GO:0099522) postsynaptic cytosol(GO:0099524)
4.6	41.4	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
4.4	70.8	GO:0033391	chromatoid body(GO:0033391)
4.4	39.7	GO:0042405	nuclear inclusion body(GO:0042405)
4.3	21.8	GO:0030015	CCR4-NOT core complex(GO:0030015)
4.3	30.2	GO:0070419	nonhomologous end joining complex(GO:0070419)
4.2	37.4	GO:0031390	Ctf18 RFC-like complex(GO:0031390)
4.1	20.5	GO:0035189	Rb-E2F complex(GO:0035189)
4.1	180.7	GO:0005657	replication fork(GO:0005657)
3.9	19.3	GO:0071797	LUBAC complex(GO:0071797)
3.7	29.8	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
3.5	56.1	GO:0070938	contractile ring(GO:0070938)
3.5	10.4	GO:0032798	Swi5-Sfr1 complex(GO:0032798) DNA recombinase mediator complex(GO:0033061)
3.4	173.1	GO:0072686	mitotic spindle(GO:0072686)
3.4	10.1	GO:0035838	growing cell tip(GO:0035838)
3.3	13.4	GO:0033553	rDNA heterochromatin(GO:0033553)
3.1	15.5	GO:0043186	P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
3.1	24.7	GO:0097443	sorting endosome(GO:0097443)
3.1	24.6	GO:0044322	endoplasmic reticulum quality control compartment(GO:0044322)
3.0	27.3	GO:0070187	telosome(GO:0070187)
3.0	41.6	GO:0035098	ESC/E(Z) complex(GO:0035098)
3.0	32.5	GO:0005721	pericentric heterochromatin(GO:0005721)
2.9	23.6	GO:0035267	NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
2.9	58.7	GO:0016581	NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
2.9	8.8	GO:0046691	intracellular canaliculus(GO:0046691)
2.9	38.0	GO:0032426	stereocilium tip(GO:0032426)
2.9	23.4	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
2.9	247.1	GO:0000793	condensed chromosome(GO:0000793)
2.8	405.4	GO:0044450	microtubule organizing center part(GO:0044450)
2.7	13.7	GO:1990604	IRE1-TRAF2-ASK1 complex(GO:1990604)
2.7	38.0	GO:0044224	juxtaparanode region of axon(GO:0044224)
2.7	45.6	GO:0035686	sperm fibrous sheath(GO:0035686)
2.7	131.4	GO:0005643	nuclear pore(GO:0005643)
2.7	21.4	GO:0061700	GATOR2 complex(GO:0061700)
2.5	5.0	GO:1990923	PET complex(GO:1990923)
2.4	55.4	GO:0030992	intraciliary transport particle B(GO:0030992)
2.4	14.3	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
2.3	21.1	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
2.3	11.7	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
2.3	25.6	GO:0005682	U5 snRNP(GO:0005682)
2.3	34.8	GO:0035102	PRC1 complex(GO:0035102)
2.3	4.6	GO:0071141	SMAD protein complex(GO:0071141)
2.3	6.9	GO:0005944	phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
2.3	4.6	GO:0032389	MutLalpha complex(GO:0032389)
2.3	6.9	GO:0071008	U2-type post-mRNA release spliceosomal complex(GO:0071008)
2.2	251.6	GO:0005913	cell-cell adherens junction(GO:0005913)
2.2	39.2	GO:0031362	anchored component of external side of plasma membrane(GO:0031362)
2.2	26.0	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
2.1	14.7	GO:0005687	U4 snRNP(GO:0005687)
2.1	16.8	GO:0005641	nuclear envelope lumen(GO:0005641)
2.1	8.3	GO:0070876	SOSS complex(GO:0070876)
2.0	10.1	GO:0030877	beta-catenin destruction complex(GO:0030877)
2.0	166.1	GO:0016363	nuclear matrix(GO:0016363)
1.9	3.8	GO:0035061	interchromatin granule(GO:0035061)
1.9	102.0	GO:0000781	chromosome, telomeric region(GO:0000781)
1.9	22.5	GO:0001741	XY body(GO:0001741)
1.9	11.2	GO:0048237	rough endoplasmic reticulum lumen(GO:0048237)
1.8	29.5	GO:0000346	transcription export complex(GO:0000346)
1.8	77.0	GO:0045171	intercellular bridge(GO:0045171)
1.8	23.7	GO:0044666	MLL3/4 complex(GO:0044666)
1.8	12.7	GO:0071203	WASH complex(GO:0071203)
1.8	21.6	GO:0045120	pronucleus(GO:0045120)
1.8	8.9	GO:0000322	storage vacuole(GO:0000322)
1.7	381.3	GO:0000790	nuclear chromatin(GO:0000790)
1.7	44.6	GO:0002080	acrosomal membrane(GO:0002080)
1.7	6.8	GO:0071065	alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
1.7	18.4	GO:0000177	cytoplasmic exosome (RNase complex)(GO:0000177)
1.7	10.0	GO:0070761	pre-snoRNP complex(GO:0070761)
1.7	11.6	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
1.7	81.0	GO:0005844	polysome(GO:0005844)
1.6	16.3	GO:0002199	zona pellucida receptor complex(GO:0002199)
1.6	24.1	GO:0030061	mitochondrial crista(GO:0030061)
1.6	78.3	GO:0017053	transcriptional repressor complex(GO:0017053)
1.6	9.4	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
1.5	10.3	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
1.4	7.2	GO:0097452	GAIT complex(GO:0097452)
1.4	20.1	GO:0042611	MHC protein complex(GO:0042611)
1.4	22.9	GO:0005849	mRNA cleavage factor complex(GO:0005849)
1.4	8.6	GO:0097422	tubular endosome(GO:0097422)
1.4	140.4	GO:0005819	spindle(GO:0005819)
1.4	7.0	GO:0000974	Prp19 complex(GO:0000974)
1.4	6.9	GO:0097550	transcriptional preinitiation complex(GO:0097550)
1.4	5.5	GO:0020016	ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
1.4	8.2	GO:0031332	RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
1.4	21.7	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
1.4	23.0	GO:0005669	transcription factor TFIID complex(GO:0005669)
1.4	8.1	GO:0030289	protein phosphatase 4 complex(GO:0030289)
1.2	7.5	GO:0036128	CatSper complex(GO:0036128)
1.2	11.1	GO:0000124	SAGA complex(GO:0000124)
1.2	18.3	GO:0032039	integrator complex(GO:0032039)
1.1	5.7	GO:1990716	axonemal central apparatus(GO:1990716)
1.1	94.5	GO:0000785	chromatin(GO:0000785)
1.1	2.2	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
1.1	3.3	GO:0005688	U6 snRNP(GO:0005688)
1.1	3.3	GO:0097651	phosphatidylinositol 3-kinase complex, class IA(GO:0005943) phosphatidylinositol 3-kinase complex, class I(GO:0097651)
1.1	75.8	GO:0005694	chromosome(GO:0005694)
1.1	39.0	GO:0005881	cytoplasmic microtubule(GO:0005881)
1.1	6.5	GO:0042406	extrinsic component of endoplasmic reticulum membrane(GO:0042406)
1.1	59.1	GO:0016605	PML body(GO:0016605)
1.0	3.9	GO:1990712	HFE-transferrin receptor complex(GO:1990712)
1.0	2.0	GO:0060091	kinocilium(GO:0060091)
1.0	62.3	GO:0071013	catalytic step 2 spliceosome(GO:0071013)
1.0	40.6	GO:0016592	mediator complex(GO:0016592)
1.0	1.9	GO:0031205	endoplasmic reticulum Sec complex(GO:0031205)
0.9	57.6	GO:0036064	ciliary basal body(GO:0036064)
0.9	51.2	GO:0005930	axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.9	7.1	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
0.9	7.0	GO:0031209	SCAR complex(GO:0031209)
0.9	27.0	GO:0031941	filamentous actin(GO:0031941)
0.9	3.5	GO:0001405	presequence translocase-associated import motor(GO:0001405)
0.9	23.3	GO:0032420	stereocilium(GO:0032420)
0.8	191.7	GO:0016607	nuclear speck(GO:0016607)
0.8	2.5	GO:0031010	ISWI-type complex(GO:0031010)
0.8	3.3	GO:0071011	precatalytic spliceosome(GO:0071011)
0.8	9.0	GO:0032541	cortical endoplasmic reticulum(GO:0032541)
0.8	20.2	GO:0046930	pore complex(GO:0046930)
0.8	98.4	GO:0005795	Golgi stack(GO:0005795)
0.8	0.8	GO:0001651	dense fibrillar component(GO:0001651)
0.8	7.0	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.8	6.8	GO:0000813	ESCRT I complex(GO:0000813)
0.7	20.0	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.7	1.5	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.7	12.1	GO:0005732	small nucleolar ribonucleoprotein complex(GO:0005732)
0.7	11.2	GO:0097449	astrocyte projection(GO:0097449)
0.7	1.4	GO:0030906	retromer, cargo-selective complex(GO:0030906)
0.7	4.7	GO:0000127	transcription factor TFIIIC complex(GO:0000127)
0.7	4.6	GO:0097504	Gemini of coiled bodies(GO:0097504)
0.6	1.9	GO:0031515	tRNA (m1A) methyltransferase complex(GO:0031515)
0.6	3.9	GO:0042824	MHC class I peptide loading complex(GO:0042824) TAP complex(GO:0042825)
0.6	1.8	GO:0035577	azurophil granule membrane(GO:0035577) tertiary granule membrane(GO:0070821)
0.6	8.3	GO:0030127	COPII vesicle coat(GO:0030127)
0.6	4.1	GO:0097524	sperm plasma membrane(GO:0097524)
0.6	3.5	GO:0034709	methylosome(GO:0034709)
0.6	3.5	GO:0031415	NatA complex(GO:0031415)
0.5	33.0	GO:0030496	midbody(GO:0030496)
0.5	5.5	GO:0005689	U12-type spliceosomal complex(GO:0005689)
0.5	3.2	GO:0070652	HAUS complex(GO:0070652)
0.5	5.4	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.5	110.3	GO:0031965	nuclear membrane(GO:0031965)
0.5	11.3	GO:0042588	zymogen granule(GO:0042588)
0.5	2.9	GO:0042765	GPI-anchor transamidase complex(GO:0042765)
0.5	11.9	GO:0005681	spliceosomal complex(GO:0005681)
0.5	2.8	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.4	1.3	GO:0030956	glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.4	3.5	GO:0008541	proteasome regulatory particle, lid subcomplex(GO:0008541)
0.4	4.6	GO:1902555	endoribonuclease complex(GO:1902555)
0.4	1.2	GO:1903349	omegasome membrane(GO:1903349) omegasome(GO:1990462)
0.4	1.6	GO:0043159	acrosomal matrix(GO:0043159)
0.4	21.7	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.4	3.3	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.3	6.9	GO:0032040	small-subunit processome(GO:0032040)
0.3	1.0	GO:0070545	PeBoW complex(GO:0070545)
0.3	6.5	GO:0015030	Cajal body(GO:0015030)
0.3	6.0	GO:1902711	GABA-A receptor complex(GO:1902711)
0.3	39.3	GO:0016604	nuclear body(GO:0016604)
0.2	19.7	GO:0001669	acrosomal vesicle(GO:0001669)
0.2	2.6	GO:0031519	PcG protein complex(GO:0031519)
0.2	19.9	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.2	6.6	GO:0005801	cis-Golgi network(GO:0005801)
0.2	5.6	GO:0008287	protein serine/threonine phosphatase complex(GO:0008287)
0.2	4.5	GO:0032993	protein-DNA complex(GO:0032993)
0.2	5.6	GO:0000123	histone acetyltransferase complex(GO:0000123)
0.2	2.5	GO:0030904	retromer complex(GO:0030904)
0.2	5.3	GO:0098636	protein complex involved in cell adhesion(GO:0098636)
0.2	10.4	GO:0045095	keratin filament(GO:0045095)
0.1	1.6	GO:0030686	90S preribosome(GO:0030686)
0.1	11.1	GO:0001650	fibrillar center(GO:0001650)
0.1	0.6	GO:0000221	vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.1	0.2	GO:0035692	macrophage migration inhibitory factor receptor complex(GO:0035692)
0.1	7.0	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
0.1	1.7	GO:0005839	proteasome core complex(GO:0005839)
0.1	0.5	GO:0033290	eukaryotic 48S preinitiation complex(GO:0033290)
0.1	0.2	GO:0030868	smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.1	0.5	GO:0030008	TRAPP complex(GO:0030008)
0.0	0.7	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
64.0	255.9	GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
46.9	187.5	GO:0061505	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
45.3	181.4	GO:0044378	non-sequence-specific DNA binding, bending(GO:0044378)
39.4	157.7	GO:0031493	nucleosomal histone binding(GO:0031493)
32.8	164.1	GO:0010997	anaphase-promoting complex binding(GO:0010997)
30.8	277.1	GO:0043515	kinetochore binding(GO:0043515)
24.6	73.8	GO:0032139	dinucleotide insertion or deletion binding(GO:0032139)
15.3	61.3	GO:0004487	methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
13.4	66.8	GO:0004104	cholinesterase activity(GO:0004104)
13.3	66.5	GO:0061676	importin-alpha family protein binding(GO:0061676)
13.0	39.1	GO:0032137	guanine/thymine mispair binding(GO:0032137)
12.5	37.6	GO:0035851	Krueppel-associated box domain binding(GO:0035851)
11.7	35.2	GO:0031762	follicle-stimulating hormone receptor binding(GO:0031762)
11.4	68.4	GO:0009378	four-way junction helicase activity(GO:0009378)
11.2	56.2	GO:0043138	3'-5' DNA helicase activity(GO:0043138)
11.1	22.1	GO:0071558	histone demethylase activity (H3-K27 specific)(GO:0071558)
10.8	53.8	GO:0044547	DNA topoisomerase binding(GO:0044547)
10.1	40.2	GO:0042610	CD8 receptor binding(GO:0042610)
9.5	66.7	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
9.5	38.0	GO:0045159	myosin II binding(GO:0045159)
9.3	18.6	GO:0001069	regulatory region RNA binding(GO:0001069)
9.2	37.0	GO:1990715	mRNA CDS binding(GO:1990715)
9.2	9.2	GO:0008263	pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263)
8.8	52.6	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
8.4	234.6	GO:0070840	dynein complex binding(GO:0070840)
8.3	33.1	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
8.2	131.8	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
8.1	40.6	GO:0097100	supercoiled DNA binding(GO:0097100)
8.1	40.6	GO:1990829	C-rich single-stranded DNA binding(GO:1990829)
8.0	217.3	GO:0035173	histone kinase activity(GO:0035173)
7.9	47.5	GO:0043141	ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
7.9	39.4	GO:0032357	oxidized DNA binding(GO:0032356) oxidized purine DNA binding(GO:0032357)
7.8	31.3	GO:0034584	piRNA binding(GO:0034584)
7.7	38.4	GO:0004169	dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
7.6	60.9	GO:0004689	phosphorylase kinase activity(GO:0004689)
7.6	37.8	GO:0032564	dATP binding(GO:0032564)
7.5	1424.3	GO:0042393	histone binding(GO:0042393)
7.3	58.6	GO:0030274	LIM domain binding(GO:0030274)
7.3	43.5	GO:0016728	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
7.2	28.9	GO:0030345	extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
7.2	14.4	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
6.6	6.6	GO:0000700	mismatch base pair DNA N-glycosylase activity(GO:0000700)
6.5	39.2	GO:0034235	GPI anchor binding(GO:0034235)
6.4	77.0	GO:0003688	DNA replication origin binding(GO:0003688)
6.3	19.0	GO:0008142	oxysterol binding(GO:0008142)
6.2	49.7	GO:0005049	nuclear export signal receptor activity(GO:0005049)
6.1	30.4	GO:0004758	serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
5.9	29.4	GO:0008310	single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
5.7	22.9	GO:0050733	RS domain binding(GO:0050733)
5.6	22.4	GO:0035614	snRNA stem-loop binding(GO:0035614)
5.6	33.5	GO:0004844	uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
5.6	22.3	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
5.6	389.3	GO:0003777	microtubule motor activity(GO:0003777)
5.5	55.3	GO:0042609	CD4 receptor binding(GO:0042609)
5.4	27.0	GO:0048248	CXCR3 chemokine receptor binding(GO:0048248)
5.3	21.3	GO:0047184	1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
5.3	84.6	GO:0004003	ATP-dependent DNA helicase activity(GO:0004003)
5.1	20.3	GO:0005131	growth hormone receptor binding(GO:0005131)
4.9	34.3	GO:0035312	5'-3' exodeoxyribonuclease activity(GO:0035312)
4.9	29.2	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
4.8	261.4	GO:0031490	chromatin DNA binding(GO:0031490)
4.7	37.7	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
4.7	18.8	GO:0004677	DNA-dependent protein kinase activity(GO:0004677)
4.7	14.0	GO:0050692	DBD domain binding(GO:0050692)
4.5	4.5	GO:0032135	DNA insertion or deletion binding(GO:0032135)
4.4	39.7	GO:1990825	sequence-specific mRNA binding(GO:1990825)
4.4	17.4	GO:0070087	chromo shadow domain binding(GO:0070087)
4.3	107.9	GO:0008536	Ran GTPase binding(GO:0008536)
4.3	51.5	GO:0003678	DNA helicase activity(GO:0003678)
4.3	119.2	GO:0097472	cyclin-dependent protein kinase activity(GO:0097472)
4.2	12.5	GO:0004852	uroporphyrinogen-III synthase activity(GO:0004852)
4.2	170.4	GO:0042605	peptide antigen binding(GO:0042605)
4.1	114.2	GO:0005540	hyaluronic acid binding(GO:0005540)
4.1	16.3	GO:0017089	glycolipid transporter activity(GO:0017089)
4.0	35.9	GO:0008494	translation activator activity(GO:0008494)
4.0	11.9	GO:0004647	phosphoserine phosphatase activity(GO:0004647)
3.9	31.4	GO:0070016	armadillo repeat domain binding(GO:0070016)
3.9	46.6	GO:0004000	adenosine deaminase activity(GO:0004000)
3.8	11.3	GO:0035241	protein-arginine omega-N monomethyltransferase activity(GO:0035241) protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242) histone methyltransferase activity (H4-R3 specific)(GO:0044020)
3.7	37.4	GO:0033170	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
3.7	22.0	GO:0070878	primary miRNA binding(GO:0070878)
3.7	25.6	GO:0003691	double-stranded telomeric DNA binding(GO:0003691)
3.6	18.1	GO:0004969	histamine receptor activity(GO:0004969)
3.5	10.6	GO:0016453	C-acetyltransferase activity(GO:0016453)
3.4	10.1	GO:0035651	AP-3 adaptor complex binding(GO:0035651)
3.3	222.1	GO:0070491	repressing transcription factor binding(GO:0070491)
3.3	29.8	GO:0046703	natural killer cell lectin-like receptor binding(GO:0046703)
3.3	89.2	GO:0031492	nucleosomal DNA binding(GO:0031492)
3.2	19.4	GO:0070728	leucine binding(GO:0070728)
3.2	12.7	GO:0004452	isopentenyl-diphosphate delta-isomerase activity(GO:0004452)
3.2	104.6	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631)
3.2	15.8	GO:0043522	leucine zipper domain binding(GO:0043522)
3.2	1898.4	GO:0046982	protein heterodimerization activity(GO:0046982)
3.2	123.2	GO:0003684	damaged DNA binding(GO:0003684)
3.2	9.5	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
3.1	107.9	GO:0043015	gamma-tubulin binding(GO:0043015)
3.1	312.9	GO:0017048	Rho GTPase binding(GO:0017048)
3.0	12.1	GO:0016433	rRNA (adenine) methyltransferase activity(GO:0016433)
3.0	9.0	GO:0016882	cyclo-ligase activity(GO:0016882)
2.9	37.5	GO:0015924	mannosyl-oligosaccharide mannosidase activity(GO:0015924)
2.9	11.5	GO:0070568	guanylyltransferase activity(GO:0070568)
2.8	14.1	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
2.8	11.2	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
2.8	8.4	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
2.8	11.0	GO:0017077	oxidative phosphorylation uncoupler activity(GO:0017077)
2.7	11.0	GO:0030614	oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
2.7	8.1	GO:0004040	amidase activity(GO:0004040)
2.6	5.2	GO:0035800	deubiquitinase activator activity(GO:0035800)
2.5	17.5	GO:0004118	cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
2.4	40.8	GO:0097602	cullin family protein binding(GO:0097602)
2.4	23.6	GO:0035198	miRNA binding(GO:0035198)
2.3	9.3	GO:0035827	rubidium ion transmembrane transporter activity(GO:0035827)
2.2	38.1	GO:0000993	RNA polymerase II core binding(GO:0000993)
2.2	126.1	GO:0004722	protein serine/threonine phosphatase activity(GO:0004722)
2.2	10.8	GO:0032552	deoxyribonucleotide binding(GO:0032552)
2.2	8.6	GO:0030622	U4atac snRNA binding(GO:0030622)
2.1	4.3	GO:0004651	polynucleotide 5'-phosphatase activity(GO:0004651)
2.1	25.3	GO:0015194	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
2.1	18.9	GO:0015037	peptide disulfide oxidoreductase activity(GO:0015037)
2.1	8.3	GO:0061665	SUMO ligase activity(GO:0061665)
2.1	18.5	GO:0000983	transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
2.1	14.4	GO:0030250	cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
2.0	19.8	GO:0045295	gamma-catenin binding(GO:0045295)
2.0	19.5	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
1.9	11.6	GO:0047696	beta-adrenergic receptor kinase activity(GO:0047696)
1.9	5.8	GO:0004315	3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315) phosphopantetheine binding(GO:0031177)
1.9	52.9	GO:0003785	actin monomer binding(GO:0003785)
1.9	11.2	GO:0016018	cyclosporin A binding(GO:0016018)
1.9	1.9	GO:0016492	G-protein coupled neurotensin receptor activity(GO:0016492)
1.9	9.3	GO:0001007	transcription factor activity, RNA polymerase III transcription factor binding(GO:0001007)
1.9	126.0	GO:0070035	ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
1.8	9.1	GO:0000155	phosphorelay sensor kinase activity(GO:0000155)
1.8	1.8	GO:0070883	pre-miRNA binding(GO:0070883)
1.8	25.5	GO:0043425	bHLH transcription factor binding(GO:0043425)
1.8	17.7	GO:0015386	potassium:proton antiporter activity(GO:0015386)
1.8	10.6	GO:0061578	Lys63-specific deubiquitinase activity(GO:0061578)
1.8	8.8	GO:1990932	5.8S rRNA binding(GO:1990932)
1.7	13.8	GO:0050291	sphingosine N-acyltransferase activity(GO:0050291)
1.7	107.8	GO:0004869	cysteine-type endopeptidase inhibitor activity(GO:0004869)
1.7	15.2	GO:0043023	ribosomal large subunit binding(GO:0043023)
1.7	13.3	GO:0009881	photoreceptor activity(GO:0009881)
1.7	11.6	GO:0008603	cAMP-dependent protein kinase regulator activity(GO:0008603)
1.6	4.9	GO:0016015	morphogen activity(GO:0016015)
1.6	57.3	GO:0008408	3'-5' exonuclease activity(GO:0008408)
1.6	16.3	GO:0016004	phospholipase activator activity(GO:0016004)
1.6	13.0	GO:0008409	5'-3' exonuclease activity(GO:0008409)
1.6	16.3	GO:0070182	DNA polymerase binding(GO:0070182)
1.6	4.7	GO:0097322	7SK snRNA binding(GO:0097322)
1.6	10.9	GO:0004415	hyalurononglucosaminidase activity(GO:0004415)
1.6	3.1	GO:0042799	histone methyltransferase activity (H4-K20 specific)(GO:0042799)
1.5	10.7	GO:0045505	dynein intermediate chain binding(GO:0045505)
1.5	25.9	GO:0017056	structural constituent of nuclear pore(GO:0017056)
1.5	9.1	GO:0016803	ether hydrolase activity(GO:0016803)
1.5	33.3	GO:0004033	aldo-keto reductase (NADP) activity(GO:0004033)
1.5	12.0	GO:0004386	helicase activity(GO:0004386)
1.5	13.4	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
1.4	5.8	GO:0030983	mismatched DNA binding(GO:0030983)
1.4	2.9	GO:0004370	glycerol kinase activity(GO:0004370)
1.4	7.2	GO:1990226	histone methyltransferase binding(GO:1990226)
1.4	18.3	GO:0070402	NADPH binding(GO:0070402)
1.4	21.0	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
1.4	11.2	GO:0015181	arginine transmembrane transporter activity(GO:0015181)
1.4	6.9	GO:0009019	tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
1.4	23.3	GO:0008253	5'-nucleotidase activity(GO:0008253)
1.4	472.0	GO:0003682	chromatin binding(GO:0003682)
1.4	5.4	GO:0019784	NEDD8-specific protease activity(GO:0019784)
1.3	4.0	GO:0008476	protein-tyrosine sulfotransferase activity(GO:0008476)
1.3	7.9	GO:0008301	DNA binding, bending(GO:0008301)
1.3	9.2	GO:0017151	DEAD/H-box RNA helicase binding(GO:0017151)
1.3	26.2	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
1.3	51.1	GO:0030544	Hsp70 protein binding(GO:0030544)
1.3	10.3	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
1.3	7.7	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
1.3	43.5	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
1.2	3.7	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
1.2	30.8	GO:0004707	MAP kinase activity(GO:0004707)
1.2	20.9	GO:0015288	porin activity(GO:0015288)
1.2	7.3	GO:0008970	phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
1.2	14.6	GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
1.2	27.9	GO:0036002	pre-mRNA binding(GO:0036002)
1.2	7.3	GO:0004471	malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
1.2	4.8	GO:0019788	NEDD8 transferase activity(GO:0019788)
1.2	35.2	GO:0001158	enhancer sequence-specific DNA binding(GO:0001158)
1.2	37.5	GO:0061733	histone acetyltransferase activity(GO:0004402) peptide-lysine-N-acetyltransferase activity(GO:0061733)
1.2	4.7	GO:0016833	oxo-acid-lyase activity(GO:0016833)
1.2	3.5	GO:1990189	peptide-serine-N-acetyltransferase activity(GO:1990189) peptide-glutamate-N-acetyltransferase activity(GO:1990190)
1.2	4.6	GO:0004771	sterol esterase activity(GO:0004771)
1.1	14.6	GO:0051010	microtubule plus-end binding(GO:0051010)
1.1	44.3	GO:0005484	SNAP receptor activity(GO:0005484)
1.1	19.3	GO:0017091	AU-rich element binding(GO:0017091)
1.0	28.5	GO:0005452	inorganic anion exchanger activity(GO:0005452)
1.0	3.0	GO:0008502	melatonin receptor activity(GO:0008502)
1.0	164.1	GO:0008017	microtubule binding(GO:0008017)
1.0	19.0	GO:0042288	MHC class I protein binding(GO:0042288)
1.0	15.9	GO:0016864	protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
1.0	2.9	GO:0003923	GPI-anchor transamidase activity(GO:0003923)
1.0	10.6	GO:0004532	exoribonuclease activity(GO:0004532)
1.0	3.8	GO:0060072	large conductance calcium-activated potassium channel activity(GO:0060072)
1.0	87.2	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.9	2.8	GO:0030158	protein xylosyltransferase activity(GO:0030158)
0.9	3.7	GO:0005136	interleukin-4 receptor binding(GO:0005136)
0.9	4.6	GO:0035325	Toll-like receptor binding(GO:0035325)
0.9	15.4	GO:0001085	RNA polymerase II transcription factor binding(GO:0001085)
0.9	12.5	GO:0070063	RNA polymerase binding(GO:0070063)
0.9	2.7	GO:0071987	WD40-repeat domain binding(GO:0071987)
0.9	345.8	GO:0004842	ubiquitin-protein transferase activity(GO:0004842)
0.9	118.4	GO:0005516	calmodulin binding(GO:0005516)
0.8	61.1	GO:0004197	cysteine-type endopeptidase activity(GO:0004197)
0.8	3.3	GO:0017070	U6 snRNA binding(GO:0017070)
0.8	13.0	GO:0070530	K63-linked polyubiquitin binding(GO:0070530)
0.8	2.4	GO:0004809	tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.8	15.2	GO:0017025	TBP-class protein binding(GO:0017025)
0.8	42.7	GO:0003725	double-stranded RNA binding(GO:0003725)
0.8	3.1	GO:0034046	poly(G) binding(GO:0034046)
0.8	11.7	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.8	28.7	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.8	6.1	GO:0016936	galactoside binding(GO:0016936)
0.7	2.2	GO:0097371	MDM2/MDM4 family protein binding(GO:0097371)
0.7	1.5	GO:0042806	fucose binding(GO:0042806)
0.7	8.6	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.7	2.1	GO:0004060	arylamine N-acetyltransferase activity(GO:0004060)
0.7	9.5	GO:0048018	receptor agonist activity(GO:0048018)
0.7	2.0	GO:0050815	phosphoserine binding(GO:0050815)
0.7	0.7	GO:0005128	erythropoietin receptor binding(GO:0005128)
0.7	24.4	GO:0003755	peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.6	1.9	GO:0070739	protein-glutamic acid ligase activity(GO:0070739)
0.6	1.3	GO:0035727	lysophosphatidic acid binding(GO:0035727)
0.6	3.6	GO:0031386	protein tag(GO:0031386)
0.6	4.7	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.6	4.6	GO:0003707	steroid hormone receptor activity(GO:0003707)
0.6	1.7	GO:0019238	cyclohydrolase activity(GO:0019238)
0.6	10.3	GO:0008199	ferric iron binding(GO:0008199)
0.6	3.4	GO:0048019	receptor antagonist activity(GO:0048019)
0.6	2.2	GO:0016635	oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.6	5.5	GO:0022820	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.6	3.3	GO:0034511	U3 snoRNA binding(GO:0034511)
0.5	2.7	GO:0061133	endopeptidase activator activity(GO:0061133)
0.5	5.3	GO:0016303	1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.5	1.6	GO:0004827	proline-tRNA ligase activity(GO:0004827)
0.5	1.0	GO:0047025	3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
0.5	14.4	GO:0031369	translation initiation factor binding(GO:0031369)
0.5	8.5	GO:0017127	cholesterol transporter activity(GO:0017127)
0.5	2.5	GO:0072345	NAADP-sensitive calcium-release channel activity(GO:0072345)
0.5	5.2	GO:0004527	exonuclease activity(GO:0004527)
0.5	2.8	GO:0070990	snRNP binding(GO:0070990)
0.4	5.4	GO:0005521	lamin binding(GO:0005521)
0.4	3.1	GO:0008934	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832)
0.4	4.0	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.4	0.9	GO:0016429	tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.4	2.2	GO:0034597	phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.4	1.2	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.4	5.4	GO:0001056	RNA polymerase III activity(GO:0001056)
0.4	15.1	GO:0004177	aminopeptidase activity(GO:0004177)
0.4	63.5	GO:0003729	mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.4	3.6	GO:0070700	BMP receptor binding(GO:0070700)
0.4	1.2	GO:0004918	interleukin-8 receptor activity(GO:0004918)
0.4	1.2	GO:0019809	spermidine binding(GO:0019809)
0.4	1.2	GO:0004699	calcium-independent protein kinase C activity(GO:0004699) TIR domain binding(GO:0070976)
0.4	3.1	GO:0031698	beta-2 adrenergic receptor binding(GO:0031698)
0.4	7.6	GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.4	5.6	GO:0042974	retinoic acid receptor binding(GO:0042974)
0.4	5.5	GO:0023026	MHC class II protein complex binding(GO:0023026)
0.4	5.8	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.4	26.2	GO:0030674	protein binding, bridging(GO:0030674)
0.3	5.8	GO:0044183	protein binding involved in protein folding(GO:0044183)
0.3	3.0	GO:0015093	ferrous iron transmembrane transporter activity(GO:0015093)
0.3	1.6	GO:0004337	dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.3	1.0	GO:0004769	steroid delta-isomerase activity(GO:0004769)
0.3	15.6	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.3	8.1	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.3	1.6	GO:0008479	queuine tRNA-ribosyltransferase activity(GO:0008479)
0.3	2.5	GO:0008172	S-methyltransferase activity(GO:0008172) cobalamin binding(GO:0031419)
0.3	1.9	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.3	4.6	GO:0009982	pseudouridine synthase activity(GO:0009982)
0.3	5.2	GO:0030331	estrogen receptor binding(GO:0030331)
0.3	22.2	GO:0000149	SNARE binding(GO:0000149)
0.3	25.8	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.3	4.2	GO:0070064	proline-rich region binding(GO:0070064)
0.3	9.3	GO:0032934	sterol binding(GO:0032934)
0.3	5.0	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.3	1.4	GO:0016505	cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656) peptidase activator activity involved in apoptotic process(GO:0016505)
0.3	3.3	GO:0030215	semaphorin receptor binding(GO:0030215)
0.3	2.2	GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.3	0.8	GO:0002060	purine nucleobase binding(GO:0002060) purine-nucleoside phosphorylase activity(GO:0004731)
0.3	3.3	GO:1902936	phosphatidylinositol bisphosphate binding(GO:1902936)
0.3	4.8	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.3	247.7	GO:0003677	DNA binding(GO:0003677)
0.3	7.2	GO:0005227	calcium activated cation channel activity(GO:0005227)
0.2	2.1	GO:0050750	low-density lipoprotein particle receptor binding(GO:0050750)
0.2	1.1	GO:0008499	UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.2	3.2	GO:0048487	beta-tubulin binding(GO:0048487)
0.2	0.7	GO:0004655	porphobilinogen synthase activity(GO:0004655)
0.2	0.4	GO:0015184	L-cystine transmembrane transporter activity(GO:0015184)
0.2	17.3	GO:0004702	receptor signaling protein serine/threonine kinase activity(GO:0004702)
0.2	8.5	GO:0008375	acetylglucosaminyltransferase activity(GO:0008375)
0.2	1.6	GO:0070034	telomerase RNA binding(GO:0070034)
0.2	10.1	GO:0019003	GDP binding(GO:0019003)
0.2	1.6	GO:0005223	intracellular cGMP activated cation channel activity(GO:0005223)
0.2	0.9	GO:0000064	L-ornithine transmembrane transporter activity(GO:0000064)
0.2	2.5	GO:0005237	inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.2	3.3	GO:0051059	NF-kappaB binding(GO:0051059)
0.2	0.9	GO:0005375	copper ion transmembrane transporter activity(GO:0005375)
0.1	4.3	GO:0043021	ribonucleoprotein complex binding(GO:0043021)
0.1	0.4	GO:0060698	endoribonuclease inhibitor activity(GO:0060698)
0.1	133.1	GO:0003723	RNA binding(GO:0003723)
0.1	0.8	GO:0004859	phospholipase inhibitor activity(GO:0004859)
0.1	4.8	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1	15.4	GO:0019887	protein kinase regulator activity(GO:0019887)
0.1	1.2	GO:0004017	adenylate kinase activity(GO:0004017)
0.1	1.6	GO:0008198	ferrous iron binding(GO:0008198)
0.1	2.1	GO:0016278	lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.1	1.4	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
0.1	0.4	GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.1	1.1	GO:0098632	protein binding involved in cell-cell adhesion(GO:0098632)
0.1	1.6	GO:0004129	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1	0.5	GO:0070300	phosphatidic acid binding(GO:0070300)
0.0	0.3	GO:0016714	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0	1.2	GO:0019706	protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0	0.6	GO:0008308	voltage-gated anion channel activity(GO:0008308)
0.0	0.2	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
0.0	0.2	GO:0010340	carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.0	0.4	GO:0004745	retinol dehydrogenase activity(GO:0004745)
0.0	0.2	GO:0070679	inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0	0.1	GO:0001716	L-amino-acid oxidase activity(GO:0001716)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
25.0	1223.1	PID FOXM1 PATHWAY	FOXM1 transcription factor network
16.5	842.3	PID PLK1 PATHWAY	PLK1 signaling events
8.3	415.9	PID FANCONI PATHWAY	Fanconi anemia pathway
8.1	105.8	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
7.0	245.8	PID AURORA B PATHWAY	Aurora B signaling
6.9	138.3	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
5.7	51.2	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
4.8	14.3	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
4.3	64.5	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
4.0	68.6	PID ATR PATHWAY	ATR signaling pathway
3.7	219.3	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
3.6	72.4	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
3.5	183.7	PID E2F PATHWAY	E2F transcription factor network
3.3	56.9	PID BARD1 PATHWAY	BARD1 signaling events
3.1	46.2	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
3.1	70.7	PID ATM PATHWAY	ATM pathway
2.5	20.3	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
2.5	45.0	PID MYC PATHWAY	C-MYC pathway
2.2	64.0	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
2.1	24.6	PID AURORA A PATHWAY	Aurora A signaling
2.0	95.3	PID TELOMERASE PATHWAY	Regulation of Telomerase
1.8	7.1	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
1.7	31.4	PID HIV NEF PATHWAY	HIV-1 Nef: Negative effector of Fas and TNF-alpha
1.7	8.4	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
1.7	50.1	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
1.5	29.9	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
1.5	16.2	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
1.4	37.1	PID GLYPICAN 1PATHWAY	Glypican 1 network
1.4	69.1	PID RHOA PATHWAY	RhoA signaling pathway
1.3	35.1	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
1.3	20.5	PID ARF 3PATHWAY	Arf1 pathway
1.2	29.9	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
1.2	121.7	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
1.0	1.9	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
1.0	14.3	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.9	41.8	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.9	49.1	PID CDC42 PATHWAY	CDC42 signaling events
0.9	6.8	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.8	4.2	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.8	54.8	PID CMYB PATHWAY	C-MYB transcription factor network
0.7	15.7	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
0.7	17.6	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.7	14.2	PID IL23 PATHWAY	IL23-mediated signaling events
0.6	22.6	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.6	21.9	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
0.6	1.7	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.6	22.1	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.6	3.3	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.5	9.3	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.5	14.8	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.4	9.8	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.4	12.5	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.3	18.9	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
0.3	11.1	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.3	1.2	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.3	2.8	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.3	2.3	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.2	2.2	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.2	8.0	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.2	7.2	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.2	5.1	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.2	3.2	PID AP1 PATHWAY	AP-1 transcription factor network
0.2	1.0	SIG PIP3 SIGNALING IN CARDIAC MYOCTES	Genes related to PIP3 signaling in cardiac myocytes
0.2	1.9	PID GMCSF PATHWAY	GMCSF-mediated signaling events
0.2	2.9	ST B CELL ANTIGEN RECEPTOR	B Cell Antigen Receptor
0.2	2.6	PID RB 1PATHWAY	Regulation of retinoblastoma protein
0.1	2.8	PID P73PATHWAY	p73 transcription factor network
0.1	3.4	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.1	1.2	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.1	1.8	ST FAS SIGNALING PATHWAY	Fas Signaling Pathway
0.1	2.1	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.1	0.7	PID EPO PATHWAY	EPO signaling pathway
0.1	0.2	PID AVB3 OPN PATHWAY	Osteopontin-mediated events
0.1	1.3	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.1	0.5	PID CD8 TCR DOWNSTREAM PATHWAY	Downstream signaling in naïve CD8+ T cells
0.0	0.7	PID IL1 PATHWAY	IL1-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
54.3	1410.6	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
25.7	410.7	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
23.9	262.7	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
16.7	399.8	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
16.5	181.1	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
14.4	158.3	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
13.9	319.8	REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A	Genes involved in APC-Cdc20 mediated degradation of Nek2A
12.0	372.8	REACTOME KINESINS	Genes involved in Kinesins
11.4	57.0	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex
10.2	61.4	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
8.8	114.2	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
8.5	34.0	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
7.7	123.5	REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX	Genes involved in Activation of the pre-replicative complex
7.7	591.0	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
7.2	121.7	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
5.8	69.7	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
5.5	164.1	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
4.8	62.9	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
4.8	66.8	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
4.7	23.4	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
4.3	270.4	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
4.2	63.4	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
4.2	8.4	REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	Genes involved in CD28 dependent PI3K/Akt signaling
4.1	57.3	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
4.0	83.1	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
4.0	39.5	REACTOME CTLA4 INHIBITORY SIGNALING	Genes involved in CTLA4 inhibitory signaling
3.5	13.9	REACTOME G2 M CHECKPOINTS	Genes involved in G2/M Checkpoints
3.2	55.0	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
3.2	41.2	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
3.1	55.6	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
3.0	3.0	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
2.8	53.2	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
2.8	27.7	REACTOME CHROMOSOME MAINTENANCE	Genes involved in Chromosome Maintenance
2.7	57.0	REACTOME G1 PHASE	Genes involved in G1 Phase
2.6	20.8	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
2.6	23.3	REACTOME REGULATORY RNA PATHWAYS	Genes involved in Regulatory RNA pathways
2.6	61.5	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
2.5	50.1	REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS	Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
2.4	234.2	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
1.9	18.6	REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE	Genes involved in Cell death signalling via NRAGE, NRIF and NADE
1.8	51.6	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
1.8	34.3	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
1.7	21.0	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
1.7	36.9	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
1.6	24.6	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
1.6	21.3	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
1.5	22.9	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
1.5	19.8	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
1.5	30.3	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
1.5	54.6	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
1.4	33.2	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
1.4	68.9	REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS	Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
1.4	53.0	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
1.3	20.1	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
1.2	24.7	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
1.1	20.3	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
1.1	19.2	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
1.0	23.0	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
1.0	4.8	REACTOME CELL CYCLE CHECKPOINTS	Genes involved in Cell Cycle Checkpoints
0.9	10.4	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.9	8.2	REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC	Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.9	43.4	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.8	129.9	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.8	94.2	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.8	22.0	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.8	39.9	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.8	6.4	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.8	13.2	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.8	6.9	REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA	Genes involved in G beta:gamma signalling through PI3Kgamma
0.8	26.6	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.7	8.8	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.7	8.7	REACTOME FORMATION OF THE HIV1 EARLY ELONGATION COMPLEX	Genes involved in Formation of the HIV-1 Early Elongation Complex
0.7	2.7	REACTOME ACYL CHAIN REMODELLING OF PI	Genes involved in Acyl chain remodelling of PI
0.6	15.7	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.6	1.8	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.6	6.6	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.6	30.9	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.6	8.3	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.6	5.7	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.6	9.6	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.6	55.6	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
0.5	5.7	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.4	13.5	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.4	4.1	REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE	Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.4	3.2	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.4	6.9	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.4	11.2	REACTOME GABA B RECEPTOR ACTIVATION	Genes involved in GABA B receptor activation
0.4	6.0	REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX	Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.4	3.3	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.3	6.4	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.3	0.6	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.3	4.4	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.3	6.2	REACTOME GABA RECEPTOR ACTIVATION	Genes involved in GABA receptor activation
0.3	8.9	REACTOME RNA POL III TRANSCRIPTION	Genes involved in RNA Polymerase III Transcription
0.2	30.7	REACTOME GENERIC TRANSCRIPTION PATHWAY	Genes involved in Generic Transcription Pathway
0.2	2.7	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.2	2.4	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.2	4.3	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.2	2.6	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.1	2.5	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
0.1	1.8	REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	Genes involved in Sema3A PAK dependent Axon repulsion
0.1	1.1	REACTOME AMYLOIDS	Genes involved in Amyloids
0.1	1.2	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.1	2.2	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.1	1.2	REACTOME CA DEPENDENT EVENTS	Genes involved in Ca-dependent events
0.1	1.5	REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL	Genes involved in Cell surface interactions at the vascular wall
0.1	2.1	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
0.1	0.6	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1	3.0	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1	1.2	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1	1.1	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	2.5	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.0	0.5	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0	0.4	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.0	0.2	REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX	Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex

Results for Ybx1_Nfya_Nfyb_Nfyc_Cebpz

Z-value: 4.86

Motif logo

Transcription factors associated with Ybx1_Nfya_Nfyb_Nfyc_Cebpz

Activity-expression correlation:

Activity profile of Ybx1_Nfya_Nfyb_Nfyc_Cebpz motif

Sorted Z-values of Ybx1_Nfya_Nfyb_Nfyc_Cebpz motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of Ybx1_Nfya_Nfyb_Nfyc_Cebpz

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: