GSE53960: rat RNA-Seq transcriptomic Bodymap

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Expression table
• Download the whole report

Gene Symbol	Gene ID	Gene Info
Spic Links NCBI RGD Ensembl	ENSRNOG00000005720	Spi-C transcription factor

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Spic	rn6_v1_chr7_-_29233392_29233392	0.86	1.2e-94	Click!

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr1_-_98521551 Show fit	103.34	ENSRNOT00000081922	Siglec10 Links NCBI RGD Ensembl Show fit	sialic acid binding Ig-like lectin 10
chrX_+_78196300 Show fit	101.44	ENSRNOT00000048695	P2ry10 Links NCBI RGD Ensembl Show fit	purinergic receptor P2Y10
chr5_-_155258392 Show fit	100.17	ENSRNOT00000017065	C1qc Links NCBI RGD Ensembl Show fit	complement C1q C chain
chr3_+_16610086 Show fit	98.34	ENSRNOT00000046231	LOC100361009 Links NCBI RGD Ensembl Show fit	rCG64257-like
chr5_+_149047681 Show fit	85.94	ENSRNOT00000015198	Laptm5 Links NCBI RGD Ensembl Show fit	lysosomal protein transmembrane 5
chr3_+_19045214 Show fit	82.01	ENSRNOT00000070878	AABR07051670.1 Links NCBI RGD Ensembl Show fit
chr2_+_186776644 Show fit	80.21	ENSRNOT00000046778	Fcrl3 Links NCBI RGD Ensembl Show fit	Fc receptor-like 3
chr1_-_98521706 Show fit	78.65	ENSRNOT00000015941	Siglec10 Links NCBI RGD Ensembl Show fit	sialic acid binding Ig-like lectin 10
chr9_-_9675110 Show fit	77.77	ENSRNOT00000073294	Vav1 Links NCBI RGD Ensembl Show fit	vav guanine nucleotide exchange factor 1
chr6_-_143590448 Show fit	77.14	ENSRNOT00000056771	Ighv8-4 Links NCBI RGD Ensembl Show fit	immunoglobulin heavy variable V8-4
chr1_+_87938042 Show fit	76.63	ENSRNOT00000027837	Map4k1 Links NCBI RGD Ensembl Show fit	mitogen activated protein kinase kinase kinase kinase 1
chr13_+_89385859 Show fit	75.83	ENSRNOT00000047434	Fcgr3a Links NCBI RGD Ensembl Show fit	Fc fragment of IgG receptor IIIa
chr4_-_164211819 Show fit	75.61	ENSRNOT00000084796	LOC497796 Links NCBI RGD Ensembl Show fit	hypothetical protein LOC497796
chr1_+_242959488 Show fit	74.77	ENSRNOT00000015668	Dock8 Links NCBI RGD Ensembl Show fit	dedicator of cytokinesis 8
chr14_-_23604834 Show fit	74.16	ENSRNOT00000002760	Stap1 Links NCBI RGD Ensembl Show fit	signal transducing adaptor family member 1
chr1_-_47502952 Show fit	73.89	ENSRNOT00000025580	Tagap Links NCBI RGD Ensembl Show fit	T-cell activation RhoGTPase activating protein
chr13_+_89386023 Show fit	69.62	ENSRNOT00000086223	Fcgr3a Links NCBI RGD Ensembl Show fit	Fc fragment of IgG receptor IIIa
chr1_-_101236065 Show fit	68.66	ENSRNOT00000066834	Cd37 Links NCBI RGD Ensembl Show fit	CD37 molecule
chr3_-_121882726 Show fit	67.69	ENSRNOT00000006308	Il1b Links NCBI RGD Ensembl Show fit	interleukin 1 beta
chr8_+_133029625 Show fit	67.20	ENSRNOT00000008809	Ccr3 Links NCBI RGD Ensembl Show fit	C-C motif chemokine receptor 3
chr1_+_201620642 Show fit	67.03	ENSRNOT00000093674	Dmbt1 Links NCBI RGD Ensembl Show fit	deleted in malignant brain tumors 1
chr9_+_8052210 Show fit	66.34	ENSRNOT00000073659	Adgre4 Links NCBI RGD Ensembl Show fit	adhesion G protein-coupled receptor E4
chr3_+_28627084 Show fit	66.03	ENSRNOT00000049884	Arhgap15 Links NCBI RGD Ensembl Show fit	Rho GTPase activating protein 15
chr4_-_163890801 Show fit	65.59	ENSRNOT00000081946	Ly49si1 Links NCBI RGD Ensembl Show fit	immunoreceptor Ly49si1
chr10_+_83655460 Show fit	65.48	ENSRNOT00000008011	Gngt2 Links NCBI RGD Ensembl Show fit	G protein subunit gamma transducin 2
chr10_-_57436368 Show fit	64.85	ENSRNOT00000056608	Scimp Links NCBI RGD Ensembl Show fit	SLP adaptor and CSK interacting membrane protein
chr13_-_61591139 Show fit	64.27	ENSRNOT00000005324	Rgs18 Links NCBI RGD Ensembl Show fit	regulator of G-protein signaling 18
chr13_-_89343868 Show fit	64.02	ENSRNOT00000058497 ENSRNOT00000035400	Fcgr2b Links NCBI RGD Ensembl Show fit	Fc fragment of IgG receptor IIb
chr20_+_6973398 Show fit	62.84	ENSRNOT00000041665	Fgd2 Links NCBI RGD Ensembl Show fit	FYVE, RhoGEF and PH domain containing 2
chr15_+_27177900 Show fit	62.64	ENSRNOT00000039925	Tlr11 Links NCBI RGD Ensembl Show fit	toll-like receptor 11
chr4_-_164406146 Show fit	62.20	ENSRNOT00000090110	Klra22 Links NCBI RGD Ensembl Show fit	killer cell lectin-like receptor subfamily A, member 22
chr11_-_66759402 Show fit	58.96	ENSRNOT00000003326	Hcls1 Links NCBI RGD Ensembl Show fit	hematopoietic cell specific Lyn substrate 1
chr1_-_227932603 Show fit	58.92	ENSRNOT00000033795	Ms4a6a Links NCBI RGD Ensembl Show fit	membrane spanning 4-domains A6A
chr4_+_78320190 Show fit	58.43	ENSRNOT00000032742 ENSRNOT00000091359	Gimap4 Links NCBI RGD Ensembl Show fit	GTPase, IMAP family member 4
chr5_-_155252003 Show fit	57.77	ENSRNOT00000017060	C1qb Links NCBI RGD Ensembl Show fit	complement C1q B chain
chr2_-_209537087 Show fit	57.71	ENSRNOT00000024344	Cd53 Links NCBI RGD Ensembl Show fit	Cd53 molecule
chr17_-_31706523 Show fit	56.19	ENSRNOT00000071312	AABR07027447.1 Links NCBI RGD Ensembl Show fit
chr4_-_164453171 Show fit	55.45	ENSRNOT00000077539 ENSRNOT00000083610 ENSRNOT00000079975	Ly49s6 Links NCBI RGD Ensembl Show fit	Ly49 stimulatory receptor 6
chr7_+_145068286 Show fit	54.71	ENSRNOT00000088956 ENSRNOT00000065753	Nckap1l Links NCBI RGD Ensembl Show fit	NCK associated protein 1 like
chr9_+_94745217 Show fit	54.10	ENSRNOT00000051338	Inpp5d Links NCBI RGD Ensembl Show fit	inositol polyphosphate-5-phosphatase D
chr9_-_52830457 Show fit	53.68	ENSRNOT00000073557	Slc40a1 Links NCBI RGD Ensembl Show fit	solute carrier family 40 member 1
chr2_+_32820322 Show fit	53.20	ENSRNOT00000013768	Cd180 Links NCBI RGD Ensembl Show fit	CD180 molecule
chr11_+_67082193 Show fit	52.78	ENSRNOT00000003129	Cd86 Links NCBI RGD Ensembl Show fit	CD86 molecule
chr4_-_164357619 Show fit	52.42	ENSRNOT00000078114	Ly49i5 Links NCBI RGD Ensembl Show fit	Ly49 inhibitory receptor 5
chr1_-_198662610 Show fit	52.34	ENSRNOT00000055012	Sept1 Links NCBI RGD Ensembl Show fit	septin 1
chr1_+_199495298 Show fit	52.03	ENSRNOT00000086003 ENSRNOT00000026748	Itgad Links NCBI RGD Ensembl Show fit	integrin subunit alpha D
chr4_-_165192647 Show fit	51.89	ENSRNOT00000086461	Klra5 Links NCBI RGD Ensembl Show fit	killer cell lectin-like receptor, subfamily A, member 5
chr19_-_55257876 Show fit	51.30	ENSRNOT00000017564	Cyba Links NCBI RGD Ensembl Show fit	cytochrome b-245 alpha chain
chrX_-_71616997 Show fit	50.52	ENSRNOT00000004406	Cxcr3 Links NCBI RGD Ensembl Show fit	C-X-C motif chemokine receptor 3
chr4_-_170932618 Show fit	50.19	ENSRNOT00000007779	Arhgdib Links NCBI RGD Ensembl Show fit	Rho GDP dissociation inhibitor beta
chr14_-_100184192 Show fit	49.84	ENSRNOT00000007044	Plek Links NCBI RGD Ensembl Show fit	pleckstrin
chr1_-_63684189 Show fit	49.34	ENSRNOT00000085651	Lilrc2 Links NCBI RGD Ensembl Show fit	leukocyte immunoglobulin-like receptor, subfamily C, member 2
chr3_+_16495748 Show fit	49.03	ENSRNOT00000045492	AABR07051533.1 Links NCBI RGD Ensembl Show fit
chr13_-_61070599 Show fit	48.68	ENSRNOT00000005251	Rgs1 Links NCBI RGD Ensembl Show fit	regulator of G-protein signaling 1
chr4_-_157252565 Show fit	48.40	ENSRNOT00000079947	Ptpn6 Links NCBI RGD Ensembl Show fit	protein tyrosine phosphatase, non-receptor type 6
chr4_-_44136815 Show fit	48.00	ENSRNOT00000086810	Tfec Links NCBI RGD Ensembl Show fit	transcription factor EC
chr10_-_103685844 Show fit	47.87	ENSRNOT00000064284	Cd300lf Links NCBI RGD Ensembl Show fit	Cd300 molecule-like family member F
chr13_-_89606326 Show fit	47.54	ENSRNOT00000029179	Fcer1g Links NCBI RGD Ensembl Show fit	Fc fragment of IgE receptor Ig
chrX_+_65271366 Show fit	47.03	ENSRNOT00000093499	Msn Links NCBI RGD Ensembl Show fit	moesin
chr4_-_157252104 Show fit	46.13	ENSRNOT00000082739	Ptpn6 Links NCBI RGD Ensembl Show fit	protein tyrosine phosphatase, non-receptor type 6
chr3_+_28416954 Show fit	45.39	ENSRNOT00000043533	Kynu Links NCBI RGD Ensembl Show fit	kynureninase
chr4_-_164306500 Show fit	45.16	ENSRNOT00000080133	Ly49i5 Links NCBI RGD Ensembl Show fit	Ly49 inhibitory receptor 5
chr4_+_163174487 Show fit	45.15	ENSRNOT00000088108	Clec9a Links NCBI RGD Ensembl Show fit	C-type lectin domain family 9, member A
chr10_+_55013703 Show fit	44.32	ENSRNOT00000032785	Pik3r5 Links NCBI RGD Ensembl Show fit	phosphoinositide-3-kinase, regulatory subunit 5
chr11_-_14304603 Show fit	43.65	ENSRNOT00000040202 ENSRNOT00000082143	Samsn1 Links NCBI RGD Ensembl Show fit	SAM domain, SH3 domain and nuclear localization signals, 1
chr1_+_215628785 Show fit	43.63	ENSRNOT00000054864	Lsp1 Links NCBI RGD Ensembl Show fit	lymphocyte-specific protein 1
chr5_+_61425746 Show fit	42.86	ENSRNOT00000064113	RGD1305807 Links NCBI RGD Ensembl Show fit	hypothetical LOC298077
chr7_-_107616038 Show fit	42.41	ENSRNOT00000088752	Sla Links NCBI RGD Ensembl Show fit	src-like adaptor
chr3_-_16753987 Show fit	42.08	ENSRNOT00000091257	AABR07051548.1 Links NCBI RGD Ensembl Show fit
chr4_-_155923079 Show fit	41.88	ENSRNOT00000013308	Clec4a3 Links NCBI RGD Ensembl Show fit	C-type lectin domain family 4, member A3
chr7_-_12899004 Show fit	41.20	ENSRNOT00000011086	Gzmm Links NCBI RGD Ensembl Show fit	granzyme M
chr19_-_10513349 Show fit	41.19	ENSRNOT00000061270	Adgrg5 Links NCBI RGD Ensembl Show fit	adhesion G protein-coupled receptor G5
chr20_-_5163247 Show fit	41.03	ENSRNOT00000001135	Aif1 Links NCBI RGD Ensembl Show fit	allograft inflammatory factor 1
chr8_+_5768811 Show fit	40.40	ENSRNOT00000013936	Mmp8 Links NCBI RGD Ensembl Show fit	matrix metallopeptidase 8
chr9_-_61528882 Show fit	39.45	ENSRNOT00000015432	Ankrd44 Links NCBI RGD Ensembl Show fit	ankyrin repeat domain 44
chr15_+_57221292 Show fit	39.40	ENSRNOT00000014502	Lcp1 Links NCBI RGD Ensembl Show fit	lymphocyte cytosolic protein 1
chr4_-_164536556 Show fit	38.70	ENSRNOT00000087796	Ly49i2 Links NCBI RGD Ensembl Show fit	Ly49 inhibitory receptor 2
chrX_+_54390733 Show fit	38.58	ENSRNOT00000004977	RGD1565785 Links NCBI RGD Ensembl Show fit	similar to chromosome X open reading frame 21
chr9_+_65614142 Show fit	37.73	ENSRNOT00000016613	Casp8 Links NCBI RGD Ensembl Show fit	caspase 8
chrX_+_1311121 Show fit	37.66	ENSRNOT00000038909	Cfp Links NCBI RGD Ensembl Show fit	complement factor properdin
chr18_+_55576239 Show fit	37.59	ENSRNOT00000050063	LOC100910979 Links NCBI RGD Ensembl Show fit	interferon-inducible GTPase 1-like
chr13_+_47602692 Show fit	37.35	ENSRNOT00000038822	Fcmr Links NCBI RGD Ensembl Show fit	Fc fragment of IgM receptor
chr2_-_203413124 Show fit	36.74	ENSRNOT00000077898 ENSRNOT00000056140	Cd101 Links NCBI RGD Ensembl Show fit	CD101 molecule
chr1_-_227506822 Show fit	36.38	ENSRNOT00000091506	Ms4a7 Links NCBI RGD Ensembl Show fit	membrane spanning 4-domains A7
chr1_+_87019975 Show fit	36.13	ENSRNOT00000041205	Lgals4 Links NCBI RGD Ensembl Show fit	galectin 4
chr6_-_140715174 Show fit	35.82	ENSRNOT00000085345	AABR07065773.1 Links NCBI RGD Ensembl Show fit
chr2_+_55835151 Show fit	35.73	ENSRNOT00000018634	Fyb Links NCBI RGD Ensembl Show fit	FYN binding protein
chr7_+_12782491 Show fit	35.69	ENSRNOT00000065093	Cnn2 Links NCBI RGD Ensembl Show fit	calponin 2
chr9_+_81518176 Show fit	35.49	ENSRNOT00000078317 ENSRNOT00000019265 ENSRNOT00000088246 ENSRNOT00000084682	Arpc2 Links NCBI RGD Ensembl Show fit	actin related protein 2/3 complex, subunit 2
chr1_-_260254600 Show fit	35.26	ENSRNOT00000019014	Blnk Links NCBI RGD Ensembl Show fit	B-cell linker
chr11_-_67756799 Show fit	35.04	ENSRNOT00000030975	Parp9 Links NCBI RGD Ensembl Show fit	poly (ADP-ribose) polymerase family, member 9
chr11_+_31560530 Show fit	34.87	ENSRNOT00000061345	Il10rb Links NCBI RGD Ensembl Show fit	interleukin 10 receptor subunit beta
chr8_-_128665988 Show fit	33.44	ENSRNOT00000050543	Csrnp1 Links NCBI RGD Ensembl Show fit	cysteine and serine rich nuclear protein 1
chr1_+_197999037 Show fit	33.23	ENSRNOT00000091065	Apobr Links NCBI RGD Ensembl Show fit	apolipoprotein B receptor
chr6_+_137323713 Show fit	32.91	ENSRNOT00000029017	Pld4 Links NCBI RGD Ensembl Show fit	phospholipase D family, member 4
chr12_-_6879154 Show fit	32.51	ENSRNOT00000001207	Alox5ap Links NCBI RGD Ensembl Show fit	arachidonate 5-lipoxygenase activating protein
chr20_-_49486550 Show fit	32.09	ENSRNOT00000048270 ENSRNOT00000076541	Prdm1 Links NCBI RGD Ensembl Show fit	PR/SET domain 1
chr9_-_26932201 Show fit	32.05	ENSRNOT00000017081	Mcm3 Links NCBI RGD Ensembl Show fit	minichromosome maintenance complex component 3
chr14_+_80195715 Show fit	32.01	ENSRNOT00000010784	Sh3tc1 Links NCBI RGD Ensembl Show fit	SH3 domain and tetratricopeptide repeats 1
chr3_+_114772603 Show fit	31.48	ENSRNOT00000073569	MGC105649 Links NCBI RGD Ensembl Show fit	hypothetical LOC302884
chr2_-_198002625 Show fit	30.37	ENSRNOT00000091888	BC028528 Links NCBI RGD Ensembl Show fit	cDNA sequence BC028528
chr18_-_28535828 Show fit	29.81	ENSRNOT00000068386	Tmem173 Links NCBI RGD Ensembl Show fit	transmembrane protein 173
chr3_+_17009089 Show fit	29.32	ENSRNOT00000048829	LOC100361052 Links NCBI RGD Ensembl Show fit	rCG64257-like
chr13_-_89433815 Show fit	29.32	ENSRNOT00000091541	Fcgr2b Links NCBI RGD Ensembl Show fit	Fc fragment of IgG receptor IIb
chr20_+_5441876 Show fit	28.94	ENSRNOT00000092476	Rps18 Links NCBI RGD Ensembl Show fit	ribosomal protein S18
chr4_-_165026414 Show fit	28.73	ENSRNOT00000071421	Klra1 Links NCBI RGD Ensembl Show fit	killer cell lectin-like receptor, subfamily A, member 1
chr10_-_103590607 Show fit	28.61	ENSRNOT00000034741	Cd300le Links NCBI RGD Ensembl Show fit	Cd300 molecule-like family member E
chr9_+_53906073 Show fit	28.23	ENSRNOT00000017813	Nab1 Links NCBI RGD Ensembl Show fit	Ngfi-A binding protein 1
chr4_-_157433467 Show fit	28.21	ENSRNOT00000028965	Lag3 Links NCBI RGD Ensembl Show fit	lymphocyte activating 3
chr17_-_34905117 Show fit	28.05	ENSRNOT00000088931	Irf4 Links NCBI RGD Ensembl Show fit	interferon regulatory factor 4
chr1_-_13175876 Show fit	27.62	ENSRNOT00000084870	Abracl Links NCBI RGD Ensembl Show fit	ABRA C-terminal like
chr9_+_81518584 Show fit	27.15	ENSRNOT00000084309	Arpc2 Links NCBI RGD Ensembl Show fit	actin related protein 2/3 complex, subunit 2
chr9_+_46840992 Show fit	27.04	ENSRNOT00000019415	Il1r2 Links NCBI RGD Ensembl Show fit	interleukin 1 receptor type 2
chr3_-_82368357 Show fit	26.89	ENSRNOT00000000052	Cd82 Links NCBI RGD Ensembl Show fit	Cd82 molecule
chr4_-_163649637 Show fit	25.60	ENSRNOT00000080873	LOC690020 Links NCBI RGD Ensembl Show fit	similar to killer cell lectin-like receptor, subfamily A, member 17
chr14_-_33150509 Show fit	25.40	ENSRNOT00000002837	Rest Links NCBI RGD Ensembl Show fit	RE1-silencing transcription factor
chr4_-_164691405 Show fit	24.99	ENSRNOT00000090979 ENSRNOT00000091932 ENSRNOT00000078219	Ly49s4 Links NCBI RGD Ensembl Show fit Ly49i2 Links NCBI RGD Ensembl Show fit	Ly49 stimulatory receptor 4 Ly49 inhibitory receptor 2
chr1_+_197999336 Show fit	24.72	ENSRNOT00000023555	Apobr Links NCBI RGD Ensembl Show fit	apolipoprotein B receptor
chr12_+_22435701 Show fit	24.51	ENSRNOT00000071325 ENSRNOT00000073757	Slc12a9 Links NCBI RGD Ensembl Show fit	solute carrier family 12, member 9
chr17_+_15762030 Show fit	24.43	ENSRNOT00000089310	Fgd3 Links NCBI RGD Ensembl Show fit	FYVE, RhoGEF and PH domain containing 3
chr6_-_103470427 Show fit	22.85	ENSRNOT00000091560 ENSRNOT00000088795 ENSRNOT00000079824	Actn1 Links NCBI RGD Ensembl Show fit	actinin, alpha 1
chr19_+_25815207 Show fit	22.72	ENSRNOT00000003980	Lyl1 Links NCBI RGD Ensembl Show fit	LYL1, basic helix-loop-helix family member
chr10_+_87774552 Show fit	22.15	ENSRNOT00000044342	Krtap9-1 Links NCBI RGD Ensembl Show fit	keratin associated protein 9-1
chr4_-_165460075 Show fit	21.92	ENSRNOT00000035522	Klra2 Links NCBI RGD Ensembl Show fit	killer cell lectin-like receptor, subfamily A, member 2
chr7_+_58814805 Show fit	21.81	ENSRNOT00000005909	Tspan8 Links NCBI RGD Ensembl Show fit	tetraspanin 8
chr1_-_221015929 Show fit	21.72	ENSRNOT00000028137	Sipa1 Links NCBI RGD Ensembl Show fit	signal-induced proliferation-associated 1
chr2_-_210934749 Show fit	21.19	ENSRNOT00000026710	Gnai3 Links NCBI RGD Ensembl Show fit	G protein subunit alpha i3
chr4_+_140886545 Show fit	21.01	ENSRNOT00000088273	Edem1 Links NCBI RGD Ensembl Show fit	ER degradation enhancing alpha-mannosidase like protein 1
chr5_+_155935554 Show fit	20.71	ENSRNOT00000031855	LOC100911993 Links NCBI RGD Ensembl Show fit	ubiquitin carboxyl-terminal hydrolase 48-like
chr3_-_130114770 Show fit	20.70	ENSRNOT00000010638	Jag1 Links NCBI RGD Ensembl Show fit	jagged 1
chr8_+_68526093 Show fit	20.44	ENSRNOT00000011385	Aagab Links NCBI RGD Ensembl Show fit	alpha- and gamma-adaptin binding protein
chr14_+_81043454 Show fit	20.42	ENSRNOT00000043609	AC114393.1 Links NCBI RGD Ensembl Show fit
chr8_+_114916122 Show fit	19.56	ENSRNOT00000074194	Tlr9 Links NCBI RGD Ensembl Show fit	toll-like receptor 9
chr14_+_76657311 Show fit	19.37	ENSRNOT00000076730	Clnk Links NCBI RGD Ensembl Show fit	cytokine-dependent hematopoietic cell linker
chr19_-_15540773 Show fit	18.90	ENSRNOT00000022359	Lpcat2 Links NCBI RGD Ensembl Show fit	lysophosphatidylcholine acyltransferase 2
chrX_-_77700269 Show fit	18.81	ENSRNOT00000092418	Cysltr1 Links NCBI RGD Ensembl Show fit	cysteinyl leukotriene receptor 1
chr1_-_192088520 Show fit	18.73	ENSRNOT00000047420	Palb2 Links NCBI RGD Ensembl Show fit	partner and localizer of BRCA2
chr19_+_37252843 Show fit	18.58	ENSRNOT00000021145	E2f4 Links NCBI RGD Ensembl Show fit	E2F transcription factor 4
chr12_+_46316236 Show fit	18.54	ENSRNOT00000001508	Prkab1 Links NCBI RGD Ensembl Show fit	protein kinase AMP-activated non-catalytic subunit beta 1
chr10_+_69412017 Show fit	18.18	ENSRNOT00000009448	Ccl2 Links NCBI RGD Ensembl Show fit	C-C motif chemokine ligand 2
chr19_-_10620671 Show fit	17.63	ENSRNOT00000021842	Ccl17 Links NCBI RGD Ensembl Show fit	C-C motif chemokine ligand 17
chr1_+_199217016 Show fit	17.17	ENSRNOT00000025732	Orai3 Links NCBI RGD Ensembl Show fit	ORAI calcium release-activated calcium modulator 3
chr6_-_86914883 Show fit	17.09	ENSRNOT00000091202	Mis18bp1 Links NCBI RGD Ensembl Show fit	MIS18 binding protein 1
chr13_-_67206688 Show fit	16.93	ENSRNOT00000003630 ENSRNOT00000090693	Pla2g4a Links NCBI RGD Ensembl Show fit	phospholipase A2 group IVA
chr8_-_122841477 Show fit	16.59	ENSRNOT00000014861	Cmtm7 Links NCBI RGD Ensembl Show fit	CKLF-like MARVEL transmembrane domain containing 7
chr10_+_86819472 Show fit	16.30	ENSRNOT00000081424	Cdc6 Links NCBI RGD Ensembl Show fit	cell division cycle 6
chr4_-_180722358 Show fit	16.24	ENSRNOT00000040645	Itpr2 Links NCBI RGD Ensembl Show fit	inositol 1,4,5-trisphosphate receptor, type 2
chr16_-_23991570 Show fit	15.94	ENSRNOT00000044198 ENSRNOT00000018854	Nat2 Links NCBI RGD Ensembl Show fit Nat1 Links NCBI RGD Ensembl Show fit	N-acetyltransferase 2 N-acetyltransferase 1
chr1_+_219481575 Show fit	15.89	ENSRNOT00000025507	Pold4 Links NCBI RGD Ensembl Show fit	DNA polymerase delta 4, accessory subunit
chr3_+_159995064 Show fit	15.76	ENSRNOT00000012606	Ttpal Links NCBI RGD Ensembl Show fit	alpha tocopherol transfer protein like
chr16_-_21362955 Show fit	15.50	ENSRNOT00000039607	Gmip Links NCBI RGD Ensembl Show fit	Gem-interacting protein
chr4_+_115024927 Show fit	15.44	ENSRNOT00000090987	Mob1a Links NCBI RGD Ensembl Show fit	MOB kinase activator 1A
chr4_-_57625147 Show fit	15.03	ENSRNOT00000074649 ENSRNOT00000078961	Ube2h Links NCBI RGD Ensembl Show fit	ubiquitin-conjugating enzyme E2H
chr2_-_208225888 Show fit	14.53	ENSRNOT00000054860	AABR07012775.1 Links NCBI RGD Ensembl Show fit
chr16_+_20293229 Show fit	14.39	ENSRNOT00000025421	Rpl18a Links NCBI RGD Ensembl Show fit	ribosomal protein L18A
chr1_-_101118825 Show fit	14.37	ENSRNOT00000066328	Rps11 Links NCBI RGD Ensembl Show fit	ribosomal protein S11
chr17_+_69634890 Show fit	14.26	ENSRNOT00000029049	Akr1c13 Links NCBI RGD Ensembl Show fit	aldo-keto reductase family 1, member C13
chr1_-_140535934 Show fit	14.11	ENSRNOT00000065457	Det1 Links NCBI RGD Ensembl Show fit	de-etiolated homolog 1 (Arabidopsis)
chr1_-_53520788 Show fit	14.10	ENSRNOT00000060121	Gpr31 Links NCBI RGD Ensembl Show fit	G protein-coupled receptor 31
chr7_+_12471824 Show fit	13.85	ENSRNOT00000068197	Sbno2 Links NCBI RGD Ensembl Show fit	strawberry notch homolog 2
chr11_-_64855353 Show fit	13.83	ENSRNOT00000089625	Cd80 Links NCBI RGD Ensembl Show fit	Cd80 molecule
chr3_+_160467552 Show fit	13.83	ENSRNOT00000066657	Stk4 Links NCBI RGD Ensembl Show fit	serine/threonine kinase 4
chr5_+_113725717 Show fit	13.53	ENSRNOT00000032248	Tek Links NCBI RGD Ensembl Show fit	TEK receptor tyrosine kinase
chr1_-_146289465 Show fit	13.52	ENSRNOT00000017362	Abhd17c Links NCBI RGD Ensembl Show fit	abhydrolase domain containing 17C
chr10_+_85978691 Show fit	13.52	ENSRNOT00000006359	Rpl19 Links NCBI RGD Ensembl Show fit	ribosomal protein L19
chr17_+_15749978 Show fit	13.36	ENSRNOT00000067311	Fgd3 Links NCBI RGD Ensembl Show fit	FYVE, RhoGEF and PH domain containing 3
chr14_+_108007724 Show fit	13.20	ENSRNOT00000014062	Xpo1 Links NCBI RGD Ensembl Show fit	exportin 1
chr12_+_22434814 Show fit	13.13	ENSRNOT00000076829	Slc12a9 Links NCBI RGD Ensembl Show fit	solute carrier family 12, member 9
chr5_+_163612518 Show fit	13.06	ENSRNOT00000071103	LOC103692519 Links NCBI RGD Ensembl Show fit	60S ribosomal protein L9 pseudogene
chr9_-_52238564 Show fit	12.92	ENSRNOT00000005073	Col5a2 Links NCBI RGD Ensembl Show fit	collagen type V alpha 2 chain
chr4_-_87019219 Show fit	12.84	ENSRNOT00000065625	Lsm5 Links NCBI RGD Ensembl Show fit	LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated
chr16_-_18766174 Show fit	12.60	ENSRNOT00000084813	Sftpd Links NCBI RGD Ensembl Show fit	surfactant protein D
chr1_+_1180932 Show fit	12.46	ENSRNOT00000087443	LOC102547056 Links NCBI RGD Ensembl Show fit	retinoic acid early-inducible protein 1-gamma-like
chr10_-_106781950 Show fit	12.40	ENSRNOT00000077495	Tmc6 Links NCBI RGD Ensembl Show fit	transmembrane channel-like gene family 6
chr9_-_42805673 Show fit	12.27	ENSRNOT00000020558	Uggt1 Links NCBI RGD Ensembl Show fit	UDP-glucose glycoprotein glucosyltransferase 1
chr1_+_234749568 Show fit	12.23	ENSRNOT00000016871	Ostf1 Links NCBI RGD Ensembl Show fit	osteoclast stimulating factor 1
chr7_-_12646960 Show fit	12.20	ENSRNOT00000014687	Prtn3 Links NCBI RGD Ensembl Show fit	proteinase 3
chr8_+_23014956 Show fit	12.18	ENSRNOT00000018009	Prkcsh Links NCBI RGD Ensembl Show fit	protein kinase C substrate 80K-H
chr17_+_80250521 Show fit	11.97	ENSRNOT00000023446	Pter Links NCBI RGD Ensembl Show fit	phosphotriesterase related
chr10_-_56289882 Show fit	11.86	ENSRNOT00000090762 ENSRNOT00000056903	Tnfsf13 Links NCBI RGD Ensembl Show fit	tumor necrosis factor superfamily member 13
chr7_-_63687978 Show fit	11.57	ENSRNOT00000009260	Tbk1 Links NCBI RGD Ensembl Show fit	TANK-binding kinase 1
chr10_+_56524468 Show fit	11.56	ENSRNOT00000022041	Gps2 Links NCBI RGD Ensembl Show fit	G protein pathway suppressor 2
chr6_+_26836216 Show fit	11.55	ENSRNOT00000077903 ENSRNOT00000011373	Ost4 Links NCBI RGD Ensembl Show fit	oligosaccharyltransferase complex subunit 4, non-catalytic
chr7_+_135803698 Show fit	11.50	ENSRNOT00000007932	Irak4 Links NCBI RGD Ensembl Show fit	interleukin-1 receptor-associated kinase 4
chr10_-_14247886 Show fit	11.48	ENSRNOT00000020504	Nubp2 Links NCBI RGD Ensembl Show fit	nucleotide binding protein 2
chr8_+_93439648 Show fit	11.38	ENSRNOT00000043008	LOC100359563 Links NCBI RGD Ensembl Show fit	ribosomal protein S20-like
chr1_+_100832324 Show fit	11.24	ENSRNOT00000056364	Il4i1 Links NCBI RGD Ensembl Show fit	interleukin 4 induced 1
chr16_+_19068783 Show fit	11.08	ENSRNOT00000017424	Cherp Links NCBI RGD Ensembl Show fit	calcium homeostasis endoplasmic reticulum protein
chr18_+_29386809 Show fit	10.89	ENSRNOT00000082079 ENSRNOT00000024825	Eif4ebp3 Links NCBI RGD Ensembl Show fit	eukaryotic translation initiation factor 4E binding protein 3
chr8_-_22308706 Show fit	10.88	ENSRNOT00000080236	Kri1 Links NCBI RGD Ensembl Show fit	KRI1 homolog
chr3_+_47453821 Show fit	10.73	ENSRNOT00000081682	Tank Links NCBI RGD Ensembl Show fit	TRAF family member-associated NFKB activator
chr10_+_86870523 Show fit	10.59	ENSRNOT00000008659	Rara Links NCBI RGD Ensembl Show fit	retinoic acid receptor, alpha
chr3_+_110918243 Show fit	10.04	ENSRNOT00000056432	Rad51 Links NCBI RGD Ensembl Show fit	RAD51 recombinase
chr5_-_134978125 Show fit	9.96	ENSRNOT00000018004	Rad54l Links NCBI RGD Ensembl Show fit	RAD54 like (S. cerevisiae)
chr14_+_86029335 Show fit	9.91	ENSRNOT00000017375	Dbnl Links NCBI RGD Ensembl Show fit	drebrin-like
chr10_-_65437143 Show fit	9.89	ENSRNOT00000017264	Nek8 Links NCBI RGD Ensembl Show fit	NIMA-related kinase 8
chr17_-_2660902 Show fit	9.77	ENSRNOT00000067979	Mfsd14b Links NCBI RGD Ensembl Show fit	major facilitator superfamily domain containing 14B
chr3_+_9792899 Show fit	9.70	ENSRNOT00000066618	Tor1b Links NCBI RGD Ensembl Show fit	torsin family 1, member B
chr6_+_129609375 Show fit	9.69	ENSRNOT00000083732	Papola Links NCBI RGD Ensembl Show fit	poly (A) polymerase alpha
chr12_+_51937175 Show fit	9.62	ENSRNOT00000056780	Pus1 Links NCBI RGD Ensembl Show fit	pseudouridylate synthase 1

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Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
27.9	111.5	GO:0002434	immune complex clearance(GO:0002434)
24.7	74.2	GO:1903969	regulation of macrophage colony-stimulating factor signaling pathway(GO:1902226) regulation of response to macrophage colony-stimulating factor(GO:1903969) regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903972) microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
23.9	47.9	GO:1902214	regulation of interleukin-4-mediated signaling pathway(GO:1902214)
23.6	94.5	GO:0033277	abortive mitotic cell cycle(GO:0033277)
22.6	67.7	GO:0046136	positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
19.7	59.0	GO:0071461	cellular response to redox state(GO:0071461)
18.2	54.7	GO:0070358	actin polymerization-dependent cell motility(GO:0070358)
17.6	52.8	GO:0002644	negative regulation of tolerance induction(GO:0002644)
17.4	52.3	GO:0007056	spindle assembly involved in female meiosis(GO:0007056)
17.2	68.7	GO:0030886	negative regulation of myeloid dendritic cell activation(GO:0030886)
17.1	51.3	GO:1904844	response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
16.0	80.2	GO:0050859	negative regulation of B cell receptor signaling pathway(GO:0050859)
15.8	47.5	GO:0002442	serotonin production involved in inflammatory response(GO:0002351) serotonin secretion involved in inflammatory response(GO:0002442) serotonin secretion by platelet(GO:0002554)
15.7	62.6	GO:2000814	positive regulation of barbed-end actin filament capping(GO:2000814)
14.7	59.0	GO:0042509	regulation of tyrosine phosphorylation of STAT protein(GO:0042509) positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
14.3	100.2	GO:0045650	negative regulation of macrophage differentiation(GO:0045650)
14.3	42.9	GO:0046864	isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865)
13.7	41.0	GO:0014739	positive regulation of muscle hyperplasia(GO:0014739)
13.5	54.1	GO:0045658	regulation of neutrophil differentiation(GO:0045658)
13.4	53.7	GO:0070839	regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395) divalent metal ion export(GO:0070839)
12.5	49.8	GO:0070560	protein secretion by platelet(GO:0070560)
12.4	161.7	GO:0038095	Fc-gamma receptor signaling pathway(GO:0038094) Fc-epsilon receptor signaling pathway(GO:0038095)
11.3	45.4	GO:0019805	quinolinate biosynthetic process(GO:0019805)
11.2	67.5	GO:0061737	leukotriene signaling pathway(GO:0061737)
10.2	61.5	GO:0002322	B cell proliferation involved in immune response(GO:0002322)
9.8	107.8	GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
9.8	19.6	GO:0032741	positive regulation of interleukin-18 production(GO:0032741)
9.4	28.1	GO:0045082	positive regulation of interleukin-10 biosynthetic process(GO:0045082)
9.0	27.0	GO:2000660	negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
8.1	32.5	GO:0002540	leukotriene production involved in inflammatory response(GO:0002540)
7.8	47.0	GO:1902966	regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
7.2	21.7	GO:0042631	cellular response to water deprivation(GO:0042631)
7.0	21.0	GO:1904380	positive regulation of retrograde protein transport, ER to cytosol(GO:1904154) endoplasmic reticulum mannose trimming(GO:1904380)
6.9	20.7	GO:0061443	endocardial cushion cell differentiation(GO:0061443)
6.3	25.4	GO:2000705	regulation of dense core granule biogenesis(GO:2000705)
6.3	18.9	GO:0006663	platelet activating factor biosynthetic process(GO:0006663)
5.7	50.9	GO:0010668	ectodermal cell differentiation(GO:0010668)
5.6	28.2	GO:0045085	negative regulation of interleukin-2 biosynthetic process(GO:0045085)
5.5	16.6	GO:0002337	B-1a B cell differentiation(GO:0002337)
5.3	32.1	GO:0051136	regulation of NK T cell differentiation(GO:0051136)
5.2	67.2	GO:0002551	mast cell chemotaxis(GO:0002551)
4.8	76.6	GO:0000185	activation of MAPKKK activity(GO:0000185)
4.7	9.4	GO:1903753	negative regulation of p38MAPK cascade(GO:1903753)
4.7	74.8	GO:0001771	immunological synapse formation(GO:0001771)
4.6	13.8	GO:0071348	cellular response to interleukin-11(GO:0071348)
4.5	13.5	GO:0048014	Tie signaling pathway(GO:0048014)
4.4	62.2	GO:0051764	actin crosslink formation(GO:0051764)
4.3	85.8	GO:0001833	inner cell mass cell proliferation(GO:0001833)
4.1	12.2	GO:0097029	mature conventional dendritic cell differentiation(GO:0097029)
4.0	11.9	GO:0002426	immunoglobulin production in mucosal tissue(GO:0002426)
3.7	14.9	GO:1990481	mRNA pseudouridine synthesis(GO:1990481)
3.6	50.5	GO:1900118	negative regulation of execution phase of apoptosis(GO:1900118)
3.6	10.7	GO:2000158	positive regulation of ubiquitin-specific protease activity(GO:2000158)
3.5	13.8	GO:0060800	regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
3.4	37.3	GO:1990001	inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
3.3	10.0	GO:0051106	regulation of DNA ligation(GO:0051105) positive regulation of DNA ligation(GO:0051106)
3.3	3.3	GO:2001270	regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270)
3.2	12.9	GO:1903225	negative regulation of endodermal cell differentiation(GO:1903225)
3.1	12.3	GO:0006011	UDP-glucose metabolic process(GO:0006011)
3.0	9.1	GO:0042539	hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
3.0	36.4	GO:0036462	TRAIL-activated apoptotic signaling pathway(GO:0036462)
3.0	48.3	GO:0050765	negative regulation of phagocytosis(GO:0050765)
2.9	35.0	GO:0060330	regulation of response to interferon-gamma(GO:0060330)
2.9	90.2	GO:0045954	positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
2.9	57.7	GO:1901741	positive regulation of myoblast fusion(GO:1901741)
2.8	16.9	GO:0031394	positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
2.7	29.8	GO:0071360	cellular response to exogenous dsRNA(GO:0071360)
2.7	8.0	GO:0070946	neutrophil mediated killing of gram-positive bacterium(GO:0070946)
2.3	16.3	GO:1904117	cellular response to vasopressin(GO:1904117)
2.3	11.6	GO:0045359	positive regulation of interferon-beta biosynthetic process(GO:0045359)
2.3	22.7	GO:0001955	blood vessel maturation(GO:0001955)
2.0	20.4	GO:0000447	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
2.0	5.9	GO:0032510	endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510) multivesicular body assembly(GO:0036258) positive regulation of centriole replication(GO:0046601) negative regulation of exosomal secretion(GO:1903542)
1.9	5.7	GO:0010760	negative regulation of macrophage chemotaxis(GO:0010760)
1.9	13.2	GO:0000056	ribosomal small subunit export from nucleus(GO:0000056)
1.8	57.8	GO:0006958	complement activation, classical pathway(GO:0006958)
1.8	5.4	GO:0010847	regulation of chromatin assembly(GO:0010847)
1.8	14.4	GO:0097327	response to antineoplastic agent(GO:0097327)
1.8	10.6	GO:0045630	positive regulation of T-helper 2 cell differentiation(GO:0045630)
1.7	45.3	GO:0030101	natural killer cell activation(GO:0030101)
1.5	18.6	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
1.5	43.7	GO:0002820	negative regulation of adaptive immune response(GO:0002820)
1.4	15.9	GO:0097068	response to thyroxine(GO:0097068)
1.4	41.2	GO:0019835	cytolysis(GO:0019835)
1.4	12.5	GO:0090070	positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
1.4	31.7	GO:0030574	collagen catabolic process(GO:0030574)
1.4	4.1	GO:0090283	regulation of protein glycosylation in Golgi(GO:0090283)
1.4	2.7	GO:0002913	positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
1.4	5.4	GO:0051343	positive regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051343)
1.2	11.1	GO:0051533	positive regulation of NFAT protein import into nucleus(GO:0051533)
1.2	5.9	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
1.1	4.6	GO:2000002	negative regulation of DNA damage checkpoint(GO:2000002)
1.1	32.1	GO:0006270	DNA replication initiation(GO:0006270)
1.1	9.9	GO:0035330	regulation of hippo signaling(GO:0035330)
1.1	69.4	GO:0043507	positive regulation of JUN kinase activity(GO:0043507)
1.1	3.3	GO:2000853	negative regulation of corticosterone secretion(GO:2000853)
1.1	44.3	GO:0043551	regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
1.1	6.4	GO:1904749	regulation of protein localization to nucleolus(GO:1904749)
1.1	13.8	GO:0046641	positive regulation of alpha-beta T cell proliferation(GO:0046641)
1.1	68.4	GO:0002224	toll-like receptor signaling pathway(GO:0002224)
1.0	3.1	GO:0006990	positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990) regulation of muscle atrophy(GO:0014735) N-terminal peptidyl-lysine acetylation(GO:0018076)
1.0	7.2	GO:0006517	protein deglycosylation(GO:0006517)
1.0	10.0	GO:0000733	DNA strand renaturation(GO:0000733)
1.0	3.0	GO:0030237	female sex determination(GO:0030237)
1.0	5.9	GO:0010835	regulation of protein ADP-ribosylation(GO:0010835) gas homeostasis(GO:0033483)
1.0	6.7	GO:0034773	histone H4-K20 trimethylation(GO:0034773)
0.9	7.5	GO:0001842	neural fold formation(GO:0001842)
0.9	164.2	GO:0002244	hematopoietic progenitor cell differentiation(GO:0002244)
0.9	28.2	GO:0001958	endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.9	33.4	GO:0060325	face morphogenesis(GO:0060325)
0.9	52.9	GO:0034605	cellular response to heat(GO:0034605)
0.9	4.3	GO:0017182	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.9	15.4	GO:0035329	hippo signaling(GO:0035329)
0.8	42.4	GO:0038083	peptidyl-tyrosine autophosphorylation(GO:0038083)
0.8	48.2	GO:0045576	mast cell activation(GO:0045576)
0.8	5.1	GO:2000622	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.8	9.9	GO:0051014	actin filament severing(GO:0051014)
0.8	1.6	GO:1903797	positive regulation of inorganic anion transmembrane transport(GO:1903797)
0.8	17.2	GO:0002115	store-operated calcium entry(GO:0002115)
0.8	36.7	GO:0002763	positive regulation of myeloid leukocyte differentiation(GO:0002763)
0.8	2.4	GO:1904211	membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.8	13.4	GO:0051084	'de novo' posttranslational protein folding(GO:0051084)
0.7	6.0	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.7	17.6	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.7	2.2	GO:0002148	hypochlorous acid metabolic process(GO:0002148) hypochlorous acid biosynthetic process(GO:0002149)
0.7	10.9	GO:0045947	negative regulation of translational initiation(GO:0045947)
0.7	12.2	GO:0006491	N-glycan processing(GO:0006491)
0.7	2.0	GO:0006059	hexitol metabolic process(GO:0006059)
0.7	15.9	GO:0000731	DNA synthesis involved in DNA repair(GO:0000731)
0.6	6.9	GO:0006516	glycoprotein catabolic process(GO:0006516)
0.6	21.2	GO:0046039	GTP metabolic process(GO:0046039)
0.6	34.9	GO:0046847	filopodium assembly(GO:0046847)
0.6	2.4	GO:2000418	positive regulation of eosinophil migration(GO:2000418)
0.6	15.5	GO:0034260	negative regulation of GTPase activity(GO:0034260)
0.6	8.0	GO:0045023	G0 to G1 transition(GO:0045023)
0.6	59.7	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.6	3.9	GO:0033129	positive regulation of histone phosphorylation(GO:0033129)
0.5	21.8	GO:1900047	negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.5	58.0	GO:0006641	triglyceride metabolic process(GO:0006641)
0.5	61.5	GO:0008360	regulation of cell shape(GO:0008360)
0.5	33.4	GO:0050715	positive regulation of cytokine secretion(GO:0050715)
0.5	4.1	GO:0016584	nucleosome positioning(GO:0016584)
0.5	1.5	GO:0042322	negative regulation of circadian sleep/wake cycle, REM sleep(GO:0042322)
0.5	5.6	GO:0032534	regulation of microvillus assembly(GO:0032534)
0.5	2.0	GO:0071802	negative regulation of podosome assembly(GO:0071802)
0.5	9.2	GO:0031163	iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.5	3.3	GO:0043550	regulation of lipid kinase activity(GO:0043550)
0.5	55.2	GO:0007127	meiosis I(GO:0007127)
0.5	2.3	GO:0036337	Fas signaling pathway(GO:0036337)
0.4	4.8	GO:0035357	peroxisome proliferator activated receptor signaling pathway(GO:0035357)
0.4	11.9	GO:0035458	cellular response to interferon-beta(GO:0035458)
0.4	11.6	GO:0046329	negative regulation of JNK cascade(GO:0046329)
0.4	3.4	GO:1901096	regulation of autophagosome maturation(GO:1901096)
0.4	11.6	GO:0018279	protein N-linked glycosylation via asparagine(GO:0018279)
0.4	10.1	GO:0070979	protein K11-linked ubiquitination(GO:0070979)
0.3	3.3	GO:0031954	positive regulation of protein autophosphorylation(GO:0031954)
0.3	13.5	GO:0097421	liver regeneration(GO:0097421)
0.3	23.3	GO:0042273	ribosomal large subunit biogenesis(GO:0042273)
0.3	33.7	GO:0007596	blood coagulation(GO:0007596) hemostasis(GO:0007599)
0.3	0.9	GO:2001288	positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.3	35.3	GO:0042113	B cell activation(GO:0042113)
0.3	23.2	GO:0003333	amino acid transmembrane transport(GO:0003333)
0.3	0.8	GO:0060459	left lung development(GO:0060459) left lung morphogenesis(GO:0060460)
0.2	30.3	GO:0051607	defense response to virus(GO:0051607)
0.2	2.9	GO:0035970	peptidyl-threonine dephosphorylation(GO:0035970)
0.2	4.9	GO:0035641	locomotory exploration behavior(GO:0035641)
0.2	2.0	GO:0051382	kinetochore assembly(GO:0051382)
0.2	2.3	GO:0030238	male sex determination(GO:0030238) nuclear body organization(GO:0030575)
0.2	7.1	GO:0010501	RNA secondary structure unwinding(GO:0010501)
0.2	8.8	GO:0071427	mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.2	1.0	GO:2000601	positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.2	2.8	GO:0001829	trophectodermal cell differentiation(GO:0001829)
0.1	1.2	GO:0006983	ER overload response(GO:0006983)
0.1	1.8	GO:0030970	retrograde protein transport, ER to cytosol(GO:0030970)
0.1	4.7	GO:0001881	receptor recycling(GO:0001881)
0.1	10.3	GO:0000956	nuclear-transcribed mRNA catabolic process(GO:0000956)
0.1	4.2	GO:0033138	positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.1	0.9	GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.1	1.4	GO:0000301	retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.1	3.0	GO:1990090	cellular response to nerve growth factor stimulus(GO:1990090)
0.1	0.9	GO:0046037	GMP metabolic process(GO:0046037)
0.0	17.4	GO:0042330	chemotaxis(GO:0006935) taxis(GO:0042330)
0.0	4.9	GO:0051291	protein heterooligomerization(GO:0051291)
0.0	0.1	GO:0009826	unidimensional cell growth(GO:0009826)
0.0	0.3	GO:1902260	negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.0	1.3	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0	1.0	GO:0006505	GPI anchor metabolic process(GO:0006505)
0.0	0.6	GO:0055078	sodium ion homeostasis(GO:0055078)
0.0	0.2	GO:0061462	protein localization to lysosome(GO:0061462)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
14.8	44.3	GO:0005944	phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
12.6	37.7	GO:0030690	Noc1p-Noc2p complex(GO:0030690)
11.8	94.5	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
10.4	62.6	GO:0036195	muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
8.1	64.8	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
6.2	55.8	GO:0031209	SCAR complex(GO:0031209)
5.9	59.3	GO:0043020	NADPH oxidase complex(GO:0043020)
4.6	22.8	GO:0030485	smooth muscle contractile fiber(GO:0030485)
4.5	18.2	GO:0044299	C-fiber(GO:0044299)
3.9	47.0	GO:0051286	cell tip(GO:0051286)
3.7	135.1	GO:0001772	immunological synapse(GO:0001772)
3.5	52.3	GO:0072687	meiotic spindle(GO:0072687)
3.3	9.9	GO:0097543	ciliary inversin compartment(GO:0097543)
3.2	12.9	GO:0005588	collagen type V trimer(GO:0005588)
3.2	15.9	GO:0043625	delta DNA polymerase complex(GO:0043625)
3.1	95.5	GO:0042588	zymogen granule(GO:0042588)
3.0	80.4	GO:0001891	phagocytic cup(GO:0001891)
2.9	23.4	GO:0044322	endoplasmic reticulum quality control compartment(GO:0044322)
2.8	8.3	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
2.6	12.8	GO:1990726	Lsm1-7-Pat1 complex(GO:1990726)
2.3	165.0	GO:0005581	collagen trimer(GO:0005581)
2.2	13.2	GO:0005642	annulate lamellae(GO:0005642)
2.2	6.5	GO:0071001	U4/U6 snRNP(GO:0071001)
2.0	31.5	GO:0005751	mitochondrial respiratory chain complex IV(GO:0005751)
2.0	19.6	GO:0032009	early phagosome(GO:0032009)
1.8	70.9	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
1.7	18.6	GO:0042555	MCM complex(GO:0042555)
1.7	58.1	GO:0098636	protein complex involved in cell adhesion(GO:0098636)
1.3	420.4	GO:0009897	external side of plasma membrane(GO:0009897)
1.3	17.1	GO:0000778	condensed nuclear chromosome kinetochore(GO:0000778)
1.2	28.4	GO:0032588	trans-Golgi network membrane(GO:0032588)
1.1	4.6	GO:0005688	U6 snRNP(GO:0005688)
1.1	9.0	GO:0044615	nuclear pore nuclear basket(GO:0044615)
1.1	3.3	GO:0035032	phosphatidylinositol 3-kinase complex, class III(GO:0035032)
1.1	18.5	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
1.0	5.2	GO:0090661	box H/ACA telomerase RNP complex(GO:0090661)
1.0	28.1	GO:0000788	nuclear nucleosome(GO:0000788)
1.0	5.9	GO:0090543	Flemming body(GO:0090543)
1.0	3.9	GO:0005885	Arp2/3 protein complex(GO:0005885)
1.0	11.5	GO:0031616	spindle pole centrosome(GO:0031616)
0.9	23.3	GO:0030687	preribosome, large subunit precursor(GO:0030687)
0.8	27.3	GO:0033017	sarcoplasmic reticulum membrane(GO:0033017)
0.8	75.7	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.8	11.6	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.8	71.1	GO:0005776	autophagosome(GO:0005776)
0.8	55.1	GO:0032587	ruffle membrane(GO:0032587)
0.7	16.3	GO:0051233	spindle midzone(GO:0051233)
0.7	5.9	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.7	46.2	GO:0001726	ruffle(GO:0001726)
0.7	70.7	GO:0005884	actin filament(GO:0005884)
0.7	4.1	GO:0000137	Golgi cis cisterna(GO:0000137)
0.6	35.7	GO:0097517	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.6	2.8	GO:0030015	CCR4-NOT core complex(GO:0030015)
0.6	40.2	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.5	6.4	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.5	10.0	GO:0000800	lateral element(GO:0000800)
0.5	46.7	GO:0017053	transcriptional repressor complex(GO:0017053)
0.5	51.6	GO:0043235	receptor complex(GO:0043235)
0.4	4.1	GO:0031010	ISWI-type complex(GO:0031010)
0.4	60.1	GO:0031252	cell leading edge(GO:0031252)
0.4	5.6	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.3	31.1	GO:0072562	blood microparticle(GO:0072562)
0.3	0.9	GO:1902560	GMP reductase complex(GO:1902560)
0.3	1.8	GO:0005785	signal recognition particle receptor complex(GO:0005785)
0.3	27.9	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.3	70.8	GO:0016323	basolateral plasma membrane(GO:0016323)
0.2	16.6	GO:0005811	lipid particle(GO:0005811)
0.2	87.1	GO:0031012	extracellular matrix(GO:0031012)
0.2	2.2	GO:0042582	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.2	4.6	GO:0060077	inhibitory synapse(GO:0060077)
0.2	6.4	GO:0080008	Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.2	27.2	GO:0016324	apical plasma membrane(GO:0016324)
0.2	78.3	GO:0009986	cell surface(GO:0009986)
0.2	4.9	GO:0030686	90S preribosome(GO:0030686)
0.2	2.3	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.2	3.3	GO:0055038	recycling endosome membrane(GO:0055038)
0.2	165.4	GO:0005887	integral component of plasma membrane(GO:0005887)
0.2	9.2	GO:0005777	peroxisome(GO:0005777) microbody(GO:0042579)
0.1	8.7	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.1	20.5	GO:0005789	endoplasmic reticulum membrane(GO:0005789)
0.1	12.4	GO:0000323	lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.1	1.3	GO:0000445	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1	4.6	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.1	614.2	GO:0016021	integral component of membrane(GO:0016021)
0.1	0.9	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.1	0.6	GO:1990393	3M complex(GO:1990393)
0.1	3.0	GO:0045171	intercellular bridge(GO:0045171)
0.1	4.8	GO:0030133	transport vesicle(GO:0030133)
0.1	4.7	GO:0005769	early endosome(GO:0005769)
0.0	0.2	GO:0071986	Ragulator complex(GO:0071986)
0.0	46.7	GO:0005886	plasma membrane(GO:0005886)
0.0	2.3	GO:0016605	PML body(GO:0016605)
0.0	40.5	GO:0016020	membrane(GO:0016020)
0.0	1.2	GO:0071013	catalytic step 2 spliceosome(GO:0071013)
0.0	0.9	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
32.2	193.0	GO:0019767	IgE receptor activity(GO:0019767)
24.7	74.2	GO:0005157	macrophage colony-stimulating factor receptor binding(GO:0005157)
15.1	45.4	GO:0016823	hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
13.5	54.1	GO:0051425	inositol bisphosphate phosphatase activity(GO:0016312) PTB domain binding(GO:0051425)
12.8	76.6	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
12.0	47.9	GO:0005136	interleukin-4 receptor binding(GO:0005136)
11.6	58.0	GO:0030229	very-low-density lipoprotein particle receptor activity(GO:0030229)
10.8	32.5	GO:0004464	arachidonate 5-lipoxygenase activity(GO:0004051) leukotriene-C4 synthase activity(GO:0004464)
10.5	94.5	GO:0019198	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
10.4	62.6	GO:0035650	AP-1 adaptor complex binding(GO:0035650)
9.6	67.0	GO:0035375	zymogen binding(GO:0035375)
9.4	37.7	GO:0035877	death effector domain binding(GO:0035877)
9.0	107.8	GO:0001608	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
8.5	93.3	GO:0019864	IgG binding(GO:0019864)
8.2	65.5	GO:0003924	GTPase activity(GO:0003924)
7.4	44.3	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
7.0	34.9	GO:0004920	interleukin-10 receptor activity(GO:0004920)
6.7	67.2	GO:0019957	C-C chemokine binding(GO:0019957)
6.6	59.3	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
6.3	50.5	GO:0016494	C-X-C chemokine receptor activity(GO:0016494) C-X-C chemokine binding(GO:0019958)
6.1	18.2	GO:0031727	CCR2 chemokine receptor binding(GO:0031727)
6.0	53.7	GO:0015093	ferrous iron transmembrane transporter activity(GO:0015093)
5.3	15.9	GO:0004060	arylamine N-acetyltransferase activity(GO:0004060)
5.3	100.2	GO:0005149	interleukin-1 receptor binding(GO:0005149)
5.0	35.3	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
4.7	18.9	GO:0047184	1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
4.7	28.2	GO:0042289	MHC class II protein binding(GO:0042289)
4.6	37.1	GO:0004630	phospholipase D activity(GO:0004630)
4.1	12.3	GO:0035251	UDP-glucosyltransferase activity(GO:0035251)
4.1	16.2	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
3.9	59.0	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
3.9	46.7	GO:0022820	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
3.9	27.0	GO:0004908	interleukin-1 receptor activity(GO:0004908)
3.8	18.8	GO:0004974	leukotriene receptor activity(GO:0004974)
3.7	11.2	GO:0001716	L-amino-acid oxidase activity(GO:0001716)
3.6	79.7	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
3.6	10.7	GO:0035800	deubiquitinase activator activity(GO:0035800)
3.5	10.6	GO:0035014	phosphatidylinositol 3-kinase regulator activity(GO:0035014)
3.1	12.5	GO:0046703	natural killer cell lectin-like receptor binding(GO:0046703)
3.0	21.2	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
2.8	8.3	GO:0001875	lipopolysaccharide receptor activity(GO:0001875)
2.7	13.5	GO:1990932	5.8S rRNA binding(GO:1990932)
2.6	20.7	GO:0005049	nuclear export signal receptor activity(GO:0005049)
2.4	49.8	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
2.3	753.3	GO:0030246	carbohydrate binding(GO:0030246)
2.1	8.3	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
1.9	21.0	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
1.9	16.9	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
1.7	13.5	GO:0004716	receptor signaling protein tyrosine kinase activity(GO:0004716)
1.7	10.0	GO:0000150	recombinase activity(GO:0000150)
1.6	11.0	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
1.5	50.7	GO:1990841	promoter-specific chromatin binding(GO:1990841)
1.4	11.1	GO:0030621	U6 snRNA binding(GO:0017070) U4 snRNA binding(GO:0030621)
1.4	48.7	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
1.3	95.6	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
1.3	25.4	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
1.2	43.7	GO:0001784	phosphotyrosine binding(GO:0001784)
1.2	18.5	GO:0004679	AMP-activated protein kinase activity(GO:0004679)
1.2	26.9	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
1.0	17.2	GO:0015279	store-operated calcium channel activity(GO:0015279)
1.0	10.0	GO:0036310	annealing helicase activity(GO:0036310)
1.0	14.9	GO:0009982	pseudouridine synthase activity(GO:0009982)
0.9	9.4	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
0.9	10.9	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.9	20.7	GO:0005112	Notch binding(GO:0005112)
0.9	42.4	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.9	69.9	GO:0003725	double-stranded RNA binding(GO:0003725)
0.8	3.4	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.8	5.9	GO:0003896	DNA primase activity(GO:0003896)
0.8	58.0	GO:0030295	protein kinase activator activity(GO:0030295)
0.8	2.4	GO:0031728	CCR3 chemokine receptor binding(GO:0031728)
0.7	46.5	GO:0019843	rRNA binding(GO:0019843)
0.7	6.4	GO:0001054	RNA polymerase I activity(GO:0001054)
0.7	15.9	GO:0003887	DNA-directed DNA polymerase activity(GO:0003887)
0.7	17.6	GO:0048020	CCR chemokine receptor binding(GO:0048020)
0.6	4.2	GO:0042030	ATPase inhibitor activity(GO:0042030)
0.6	23.8	GO:0003678	DNA helicase activity(GO:0003678)
0.6	29.8	GO:0030551	cyclic nucleotide binding(GO:0030551)
0.5	134.1	GO:0005096	GTPase activator activity(GO:0005096)
0.5	86.6	GO:0051015	actin filament binding(GO:0051015)
0.5	50.3	GO:0001948	glycoprotein binding(GO:0001948)
0.4	3.1	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.4	25.2	GO:0051219	phosphoprotein binding(GO:0051219)
0.4	42.9	GO:0017124	SH3 domain binding(GO:0017124)
0.4	52.7	GO:0005085	guanyl-nucleotide exchange factor activity(GO:0005085)
0.4	11.5	GO:0051539	4 iron, 4 sulfur cluster binding(GO:0051539)
0.4	43.8	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.4	22.2	GO:0016279	lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.4	11.1	GO:0016676	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.4	5.9	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.4	137.6	GO:0005525	GTP binding(GO:0005525)
0.3	11.9	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.3	1.6	GO:0015321	sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.3	6.2	GO:0032183	SUMO binding(GO:0032183)
0.3	0.9	GO:0016657	GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.3	9.1	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631)
0.3	15.1	GO:0008186	RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.3	6.5	GO:0042923	neuropeptide binding(GO:0042923)
0.2	12.9	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.2	5.9	GO:0048487	beta-tubulin binding(GO:0048487)
0.2	2.7	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.2	1.5	GO:0043495	protein anchor(GO:0043495)
0.2	2.9	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.2	14.1	GO:0005178	integrin binding(GO:0005178)
0.2	4.6	GO:0098632	protein binding involved in cell-cell adhesion(GO:0098632)
0.1	0.9	GO:0019870	potassium channel inhibitor activity(GO:0019870)
0.1	2.3	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.1	50.2	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.1	2.1	GO:0016891	endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891)
0.1	0.8	GO:0070697	activin receptor binding(GO:0070697)
0.1	1.8	GO:0042288	MHC class I protein binding(GO:0042288)
0.1	14.6	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.1	8.7	GO:0003714	transcription corepressor activity(GO:0003714)
0.1	1.0	GO:0048365	Rac GTPase binding(GO:0048365)
0.1	2.2	GO:0004601	peroxidase activity(GO:0004601)
0.0	6.5	GO:0015293	symporter activity(GO:0015293)
0.0	0.6	GO:0050750	low-density lipoprotein particle receptor binding(GO:0050750)
0.0	0.6	GO:0005248	voltage-gated sodium channel activity(GO:0005248)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
11.8	213.1	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
6.2	86.5	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
5.1	347.3	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
4.2	37.7	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
3.7	168.7	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
3.2	35.3	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
2.3	65.5	PID CONE PATHWAY	Visual signal transduction: Cones
2.3	66.6	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
2.3	128.1	PID RAC1 PATHWAY	RAC1 signaling pathway
2.2	71.7	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
2.2	60.6	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
1.8	52.0	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
1.8	39.1	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
1.5	241.1	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
1.5	40.0	PID IL1 PATHWAY	IL1-mediated signaling events
1.4	18.2	PID GMCSF PATHWAY	GMCSF-mediated signaling events
1.3	18.6	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
1.3	57.3	PID CXCR4 PATHWAY	CXCR4-mediated signaling events
1.3	52.6	PID RHOA PATHWAY	RhoA signaling pathway
1.2	35.7	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
1.2	52.3	PID AURORA B PATHWAY	Aurora B signaling
1.1	13.2	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
1.1	59.3	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.9	20.3	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.8	52.9	PID CMYB PATHWAY	C-MYB transcription factor network
0.8	13.5	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.8	18.5	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
0.8	37.0	PID PDGFRB PATHWAY	PDGFR-beta signaling pathway
0.8	28.1	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.8	51.5	PID E2F PATHWAY	E2F transcription factor network
0.6	18.7	PID FANCONI PATHWAY	Fanconi anemia pathway
0.5	5.4	PID RHODOPSIN PATHWAY	Visual signal transduction: Rods
0.5	18.8	PID ENDOTHELIN PATHWAY	Endothelins
0.5	8.3	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.5	14.0	PID BARD1 PATHWAY	BARD1 signaling events
0.5	2.3	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.4	15.4	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.4	7.5	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.4	15.8	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.3	35.1	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
0.3	5.1	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.3	12.9	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.3	67.0	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.2	3.4	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.2	3.3	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.2	5.2	PID TELOMERASE PATHWAY	Regulation of Telomerase
0.1	3.8	PID IL4 2PATHWAY	IL4-mediated signaling events
0.1	3.9	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.1	4.7	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
0.1	2.1	PID P53 REGULATION PATHWAY	p53 pathway
0.1	13.7	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1	0.6	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.0	0.9	PID P73PATHWAY	p73 transcription factor network
0.0	9.1	NABA MATRISOME ASSOCIATED	Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors
0.0	0.4	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
14.4	157.9	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
9.0	107.8	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
8.1	130.3	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
7.2	144.4	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
7.1	21.2	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
5.0	45.4	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
4.9	238.8	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
4.5	45.5	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
4.3	47.5	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
3.8	109.8	REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA	Genes involved in G beta:gamma signalling through PI3Kgamma
3.6	32.5	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
3.4	37.7	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
3.1	153.5	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
2.4	94.7	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
2.4	16.9	REACTOME ADP SIGNALLING THROUGH P2RY1	Genes involved in ADP signalling through P2Y purinoceptor 1
2.4	35.3	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
2.1	18.5	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
2.0	298.1	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
2.0	19.8	REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
1.9	53.7	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
1.7	20.7	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
1.7	18.6	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
1.6	47.0	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
1.4	18.8	REACTOME EICOSANOID LIGAND BINDING RECEPTORS	Genes involved in Eicosanoid ligand-binding receptors
1.4	15.9	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
1.4	40.4	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
1.4	21.7	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
1.4	16.2	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
1.3	34.9	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
1.2	11.9	REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS	Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
1.1	22.8	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
1.1	11.3	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
1.1	59.0	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
1.1	24.7	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
1.0	13.5	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.9	22.7	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.9	13.2	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.8	115.9	REACTOME G ALPHA I SIGNALLING EVENTS	Genes involved in G alpha (i) signalling events
0.8	4.8	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.8	3.1	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.8	10.0	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.7	5.9	REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND	Genes involved in Processive synthesis on the lagging strand
0.7	18.9	REACTOME ACYL CHAIN REMODELLING OF PC	Genes involved in Acyl chain remodelling of PC
0.6	28.1	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.5	49.8	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.5	21.2	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.5	11.0	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.5	49.7	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.5	27.9	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.4	5.2	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
0.4	9.9	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.4	3.3	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.4	11.8	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.3	6.4	REACTOME RNA POL I TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase I Transcription Termination
0.3	24.3	REACTOME TOLL RECEPTOR CASCADES	Genes involved in Toll Receptor Cascades
0.3	3.3	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.3	12.9	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.3	9.0	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.3	5.9	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1	10.6	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.1	2.8	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.1	3.4	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1	10.7	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1	6.5	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.1	0.9	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.6	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	1.5	REACTOME G ALPHA S SIGNALLING EVENTS	Genes involved in G alpha (s) signalling events
0.0	1.0	REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS	Genes involved in Glycerophospholipid biosynthesis