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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Sox17

Z-value: 0.91

Motif logo

Transcription factors associated with Sox17

Gene Symbol Gene ID Gene Info
ENSRNOG00000027357 SRY box 17

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Sox17rn6_v1_chr5_+_14890408_14890408-0.424.8e-15Click!

Activity profile of Sox17 motif

Sorted Z-values of Sox17 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_161246351 37.25 ENSRNOT00000020348
troponin C2, fast skeletal type
chr16_-_75581325 26.22 ENSRNOT00000058031
defensin beta 33
chr10_+_4953879 25.46 ENSRNOT00000003455
transition protein 2
chr1_-_101210675 25.37 ENSRNOT00000028082
dickkopf like acrosomal protein 1
chr9_+_15582564 23.51 ENSRNOT00000020640
uncharacterized LOC100912849
chr1_+_215666628 20.53 ENSRNOT00000040598
ENSRNOT00000066135
ENSRNOT00000051425
ENSRNOT00000080339
ENSRNOT00000066896
ENSRNOT00000063918
troponin T3, fast skeletal type
chr14_+_96300596 19.30 ENSRNOT00000071967
similar to Spindlin-like protein 2 (SPIN-2)
chr13_-_47331187 19.26 ENSRNOT00000035577
ENSRNOT00000049915
zona pellucida 3 receptor
chrX_+_43745604 19.01 ENSRNOT00000040825
rCG36365-like
chr16_+_72086878 18.62 ENSRNOT00000023756
ENSRNOT00000078085
ADAM metallopeptidase domain 3A
chr1_-_67302751 17.62 ENSRNOT00000041518
vomeronasal 1 receptor 42
chrX_+_133227660 17.59 ENSRNOT00000004591
actin-related protein T1
chr19_-_53477420 16.65 ENSRNOT00000071344
hypothetical protein LOC687560
chr4_+_5644260 16.44 ENSRNOT00000041876
ARP3 actin related protein 3 homolog B
chr9_+_4731914 15.62 ENSRNOT00000061893

chr11_+_62584959 15.46 ENSRNOT00000071065
GRAM domain containing 1C
chr10_-_70735742 15.32 ENSRNOT00000077035
HEAT repeat containing 9
chr3_-_149356160 15.32 ENSRNOT00000037589
ENSRNOT00000081775
Sad1 and UNC84 domain containing 5
chr10_-_85717511 15.29 ENSRNOT00000005445
hypothetical protein LOC691189
chr9_-_50820290 15.09 ENSRNOT00000050748
uncharacterized LOC102548013
chr13_-_47916185 14.97 ENSRNOT00000087793
dual specificity tyrosine phosphorylation regulated kinase 3
chr1_+_185673177 14.71 ENSRNOT00000048020
SRY box 6
chr5_-_77408323 14.71 ENSRNOT00000046857
ENSRNOT00000046760
alpha-2u globulin PGCL5
major urinary protein 4
chr3_+_15379109 14.68 ENSRNOT00000036495
MORN repeat containing 5
chr5_-_77492013 14.57 ENSRNOT00000012293
alpha-2u globulin PGCL5
chr5_-_77342299 13.54 ENSRNOT00000075994
similar to alpha-2u-globulin
chr11_+_88095170 13.33 ENSRNOT00000041557
coiled-coil domain containing 116
chr5_-_77433847 13.10 ENSRNOT00000076906
ENSRNOT00000043056
similar to alpha-2u globulin PGCL2
major urinary protein 4
chr8_-_84522588 12.92 ENSRNOT00000076213
muscular LMNA-interacting protein
chr14_-_21944921 12.86 ENSRNOT00000060273
casein alpha s2-like A
chr5_-_77903062 12.80 ENSRNOT00000073954
ENSRNOT00000059320
ENSRNOT00000089382
ENSRNOT00000076074
ENSRNOT00000074349
major urinary protein-like
alpha2u globulin (LOC298111), mRNA
chr5_-_77316764 12.52 ENSRNOT00000071395
ENSRNOT00000076464
major urinary protein 4
chr13_+_83721300 12.49 ENSRNOT00000082677
adenylate cyclase 10 (soluble)
chr2_-_122756842 12.47 ENSRNOT00000080181
coiled-coil domain containing 144B
chr16_+_18648866 12.35 ENSRNOT00000014862
DPY30 domain containing 1
chr8_+_18430302 12.12 ENSRNOT00000008341
methyl-CpG binding domain protein 3-like 1
chr16_+_51748970 12.00 ENSRNOT00000059182
a disintegrin and metallopeptidase domain 26A
chrX_-_123092217 11.98 ENSRNOT00000039710
predicted gene 14569
chr2_+_189423559 11.13 ENSRNOT00000029076
tropomyosin 3
chr3_+_94035905 11.06 ENSRNOT00000014767
similar to RIKEN cDNA A930018P22
chr4_+_162077188 11.03 ENSRNOT00000090431
C-type lectin domain family 2 member D-related protein-like
chrX_+_110233170 10.89 ENSRNOT00000036019
RIKEN cDNA 4930513O06 gene
chrX_+_115721251 10.88 ENSRNOT00000060090
TRPC5 opposite strand
chr3_-_14610546 10.74 ENSRNOT00000060011
ABO-family member 6
chr7_+_66624512 10.42 ENSRNOT00000079410
ubiquitin specific peptidase 15
chr2_-_3124543 10.02 ENSRNOT00000036547
family with sequence similarity 81, member B
chr11_-_36533073 10.00 ENSRNOT00000033486
LCA5L, lebercilin like
chr13_+_95983809 9.92 ENSRNOT00000078258

chrX_+_158053164 9.65 ENSRNOT00000003235
placenta-specific 1
chr2_+_92549479 9.43 ENSRNOT00000082912
GTPase activating protein testicular GAP1
chr8_-_27907911 8.80 ENSRNOT00000010045
galactosidase, beta 1-like 3
chr1_+_190072420 8.63 ENSRNOT00000037026
ATP-binding cassette, subfamily A (ABC1), member 15
chr5_-_58484900 8.24 ENSRNOT00000012386
family with sequence similarity 214, member B
chr15_+_57709043 8.02 ENSRNOT00000030579
glutamate-rich 6B
chrX_-_60942845 7.85 ENSRNOT00000067446
melanoma antigen, family B-like 1
chr7_-_130827152 7.82 ENSRNOT00000019406
synaptotagmin 10
chr4_+_166040503 7.56 ENSRNOT00000063869
proline-rich protein BstNI subfamily 3
chr6_-_141957537 7.55 ENSRNOT00000090358
immunoglobulin heavy variable 13-2
chr19_+_6046665 7.51 ENSRNOT00000084126
cadherin 8
chrX_+_124268129 7.13 ENSRNOT00000035489
Reproductive homeobox 13
chr4_-_178441547 6.96 ENSRNOT00000087434
ENSRNOT00000055542
SRY box 5
chr8_+_53411316 6.95 ENSRNOT00000011107
ENSRNOT00000086957
transmembrane protease, serine 5
chr10_-_62664466 6.92 ENSRNOT00000078730
GIT ArfGAP 1
chr3_+_3272193 6.78 ENSRNOT00000044284
lipocalin 9
chr3_+_132052612 6.67 ENSRNOT00000030148

chr7_-_143956668 6.58 ENSRNOT00000018809
aladin WD repeat nucleoporin
chr3_-_120404910 6.40 ENSRNOT00000051783
BUB1 mitotic checkpoint serine/threonine kinase
chr20_+_27129291 6.37 ENSRNOT00000031053

chr2_+_194433808 6.23 ENSRNOT00000074310
similar to TDPOZ2
chr5_-_77294735 6.14 ENSRNOT00000018209
ENSRNOT00000056900
zinc finger protein 37
chr3_-_45169118 6.06 ENSRNOT00000086371
coiled-coil domain containing 148
chr4_-_157486844 6.01 ENSRNOT00000038281
ENSRNOT00000022874
COP9 signalosome subunit 7A
chr10_+_89069256 5.72 ENSRNOT00000008576
tubulin, gamma 2
chr2_-_187401786 5.70 ENSRNOT00000025624
hyaluronan and proteoglycan link protein 2
chr1_+_83626639 5.65 ENSRNOT00000028261
cytochrome P450, family 2, subfamily g, polypeptide 1
chr3_+_143109316 5.57 ENSRNOT00000006555
cystatin SC
chr7_+_71023976 5.35 ENSRNOT00000005679
tachykinin 3
chr18_-_37132223 5.24 ENSRNOT00000091634
protein phosphatase 2, regulatory subunit B, beta
chr10_-_40381886 5.16 ENSRNOT00000050213
nuclease-sensitive element-binding protein 1-like
chr2_-_149088787 4.85 ENSRNOT00000064833
clarin 1
chr9_+_14779772 4.76 ENSRNOT00000040323

chr7_+_130357643 4.61 ENSRNOT00000040769
kelch domain containing 7B
chr5_+_162323373 4.13 ENSRNOT00000033150
arylacetamide deacetylase-like 3
chr1_-_228263198 4.06 ENSRNOT00000028572
olfactory receptor 1874
chr6_+_111476768 4.02 ENSRNOT00000016479
SRA stem-loop interacting RNA binding protein
chr11_-_71523267 4.01 ENSRNOT00000033026
zinc finger, DHHC-type containing 19
chr3_-_22952063 4.00 ENSRNOT00000083850
proteasome subunit beta 7
chr20_-_11556312 3.90 ENSRNOT00000091856
similar to chromosome 21 open reading frame 29
chrX_-_104726816 3.77 ENSRNOT00000005165
tetraspanin 6
chr2_+_263212051 3.77 ENSRNOT00000089396
neuronal growth regulator 1
chr5_-_139505065 3.75 ENSRNOT00000013899
CTP synthase 1
chr12_+_47103314 3.71 ENSRNOT00000064910
ring finger protein 10
chr10_-_57606171 3.71 ENSRNOT00000009015
nucleoporin 88
chr9_+_6970507 3.67 ENSRNOT00000079488
ST6 beta-galactoside alpha-2,6-sialyltransferase 2
chr14_-_21299068 3.62 ENSRNOT00000065778
amelotin
chr3_-_143408604 3.52 ENSRNOT00000073262

chr3_+_167787111 3.45 ENSRNOT00000051082

chr1_-_169050963 3.43 ENSRNOT00000042637
olfactory receptor 131
chr1_+_171188133 3.40 ENSRNOT00000026511
olfactory receptor 231
chr16_+_2379480 3.07 ENSRNOT00000079215
dynein, axonemal, heavy chain 12
chr8_-_104335729 3.07 ENSRNOT00000015821
ring finger protein 7
chr2_+_195039054 3.00 ENSRNOT00000072634
ENSRNOT00000044412
TD and POZ domain-containing protein 2-like
chr3_-_15379381 2.91 ENSRNOT00000084069
NADH:ubiquinone oxidoreductase subunit A8
chr4_-_165810121 2.82 ENSRNOT00000048210
taste receptor, type 2, member 104
chr12_+_18936594 2.82 ENSRNOT00000081587
sprouty RTK signaling antagonist 3
chr3_+_148035166 2.80 ENSRNOT00000055409
defensin beta 19
chr8_+_85605655 2.71 ENSRNOT00000086145
ENSRNOT00000085958

chr6_-_142635763 2.65 ENSRNOT00000048908

chr1_-_149914606 2.62 ENSRNOT00000044773
olfactory receptor 19
chr1_+_220423426 2.57 ENSRNOT00000072647
breast cancer metastasis-suppressor 1
chr1_-_61626454 2.53 ENSRNOT00000038190
vomeronasal 1 receptor 22
chr4_+_1658278 2.53 ENSRNOT00000073845
olfactory receptor 1250
chr3_+_3000477 2.52 ENSRNOT00000064437
odorant binding protein 2B
chr19_-_17045349 2.50 ENSRNOT00000086829
FTO, alpha-ketoglutarate dependent dioxygenase
chrX_+_29504349 2.37 ENSRNOT00000005981
transcription elongation factor A N-terminal and central domain containing
chr19_-_29968424 2.37 ENSRNOT00000024981
inositol polyphosphate-4-phosphatase type II B
chr9_+_88494676 2.36 ENSRNOT00000089451
mitochondrial fission factor-like
chrX_-_106085878 2.29 ENSRNOT00000049735
preferentially expressed antigen in melanoma
chr5_-_165083487 2.28 ENSRNOT00000036647
dispatched RND transporter family member 3
chr10_-_75171774 2.19 ENSRNOT00000011735
eosinophil peroxidase
chr13_+_91711995 2.18 ENSRNOT00000040596
olfactory receptor 1582
chr1_-_99135977 2.14 ENSRNOT00000056515
vomeronasal 2 receptor, 38
chr4_+_102876038 2.08 ENSRNOT00000085205

chrX_+_99250516 2.01 ENSRNOT00000039260
similar to DNA segment, Chr 5, ERATO Doi 577, expressed
chr3_-_102484517 1.98 ENSRNOT00000006522
olfactory receptor 750
chr6_-_140572023 1.95 ENSRNOT00000072338

chr11_-_28979169 1.89 ENSRNOT00000061601

chr2_+_36093301 1.89 ENSRNOT00000074521
serine protease inhibitor Kazal-type 12-like
chrX_-_43015896 1.89 ENSRNOT00000075045
serine protease inhibitor Kazal-type 12-like
chr2_-_199529864 1.88 ENSRNOT00000023742
olfactory receptor 390
chr3_+_160660749 1.85 ENSRNOT00000018456
seminal vesicle secretory protein 4
chr10_+_65552897 1.79 ENSRNOT00000056217
sperm associated antigen 5
chr10_-_27427686 1.71 ENSRNOT00000087475

chr9_-_81880105 1.69 ENSRNOT00000022677
ring finger protein 25
chr4_+_148623770 1.69 ENSRNOT00000051285
olfactory receptor 828
chr2_+_180936688 1.69 ENSRNOT00000016039
acid sensing ion channel subunit family member 5
chr3_+_79187055 1.68 ENSRNOT00000050785
olfactory receptor 745
chr1_-_216744066 1.68 ENSRNOT00000087961
nucleosome assembly protein 1-like 4
chr1_+_61095171 1.64 ENSRNOT00000042702
vomeronasal 1 receptor 19
chr9_+_52393779 1.58 ENSRNOT00000072809
similar to large subunit ribosomal protein L36a
chr3_-_20479999 1.54 ENSRNOT00000050573

chr9_+_24170858 1.54 ENSRNOT00000081915

chr5_-_69578458 1.53 ENSRNOT00000082758
olfactory receptor 851
chr6_-_141321108 1.50 ENSRNOT00000040556

chr16_-_75262002 1.49 ENSRNOT00000046156
defensin beta 50
chr3_+_19141133 1.49 ENSRNOT00000058323

chr4_+_148567386 1.46 ENSRNOT00000047844
olfactory receptor 826
chr10_-_82374171 1.44 ENSRNOT00000032693
essential meiotic structure-specific endonuclease 1
chr15_-_27968358 1.44 ENSRNOT00000040616
ribonuclease A family member 9
chr10_-_44082313 1.43 ENSRNOT00000051126
olfactory receptor 1421
chr20_+_5008508 1.38 ENSRNOT00000001153
von Willebrand factor A domain containing 7
chr15_+_18332910 1.28 ENSRNOT00000085822
family with sequence similarity 3, member D
chr10_-_56935141 1.25 ENSRNOT00000025910
arachidonate 12-lipoxygenase, epidermal
chr4_-_164015365 1.19 ENSRNOT00000078121
immunoreceptor Ly49si2
chr4_+_93888502 1.12 ENSRNOT00000090783

chr6_-_26135952 1.08 ENSRNOT00000084751
mitochondrial ribosomal protein L33
chr7_-_11018160 1.08 ENSRNOT00000092061
amino-terminal enhancer of split
chr4_+_157726941 1.07 ENSRNOT00000025081
vesicle-associated membrane protein 1
chr1_+_213374895 1.05 ENSRNOT00000041052
olfactory receptor 311
chr15_-_29623597 1.05 ENSRNOT00000074483

chr4_-_166979391 1.05 ENSRNOT00000052034
taste receptor, type 2, member 136
chr6_-_123577695 1.04 ENSRNOT00000006604
forkhead box N3
chr3_-_119075606 1.02 ENSRNOT00000041569
ENSRNOT00000086724
histidine decarboxylase
chr1_+_89724303 1.01 ENSRNOT00000030687
secretoglobin, family 2B, member 2
chr9_-_14654305 1.00 ENSRNOT00000065673
similar to RIKEN cDNA B430306N03 gene
chr15_-_29360198 0.99 ENSRNOT00000072745
T-cell receptor alpha chain V region PHDS58-like
chr2_+_83393282 0.91 ENSRNOT00000044871
catenin delta 2
chr3_-_103485806 0.88 ENSRNOT00000072524
olfactory receptor 789
chrX_+_135550834 0.81 ENSRNOT00000048922
RNA binding motif protein, X-linked 2
chr8_-_43024557 0.81 ENSRNOT00000073494
olfactory receptor 1273
chr3_+_77152425 0.78 ENSRNOT00000092045
ENSRNOT00000082255
olfactory receptor 653
chr3_-_73653583 0.72 ENSRNOT00000073787
olfactory receptor 493
chr3_-_73801471 0.70 ENSRNOT00000090035
olfactory receptor 507
chr1_+_64849657 0.65 ENSRNOT00000081724
ENSRNOT00000086867
vomeronasal 2 receptor, 12
chr3_-_158936972 0.64 ENSRNOT00000074733
olfactory receptor 1254
chr4_+_1584083 0.61 ENSRNOT00000087099
olfactory receptor 1244
chrX_-_77559348 0.59 ENSRNOT00000047823
fibronectin type III domain containing 3C1
chr2_+_159138758 0.59 ENSRNOT00000087942

chr15_+_32386816 0.58 ENSRNOT00000060322

chr1_+_66963035 0.56 ENSRNOT00000043603
60S ribosomal protein L36a-like
chr3_+_19128400 0.52 ENSRNOT00000074272

chr1_-_200548317 0.48 ENSRNOT00000088610

chr10_-_43947494 0.46 ENSRNOT00000052223
olfactory receptor 1416
chr15_+_31579478 0.44 ENSRNOT00000071642

chr6_+_128046780 0.40 ENSRNOT00000078064
Ab1-233
chr13_-_91735361 0.40 ENSRNOT00000058090
Fc fragment of IgE receptor Ia
chr10_+_34578356 0.38 ENSRNOT00000047454
olfactory receptor 1389
chr6_-_142479939 0.36 ENSRNOT00000091268

chr8_+_20265891 0.36 ENSRNOT00000048326
olfactory receptor 1166
chr5_+_169898302 0.28 ENSRNOT00000087911

chr9_+_84569597 0.23 ENSRNOT00000020161
acyl-CoA synthetase long-chain family member 3
chr6_+_137997335 0.22 ENSRNOT00000006872
transmembrane protein 121
chr8_-_39907478 0.21 ENSRNOT00000064141
roundabout guidance receptor 3
chr3_+_75322884 0.21 ENSRNOT00000066249
olfactory receptor 556
chr3_-_103203299 0.19 ENSRNOT00000047208
olfactory receptor 783
chr8_-_53758774 0.19 ENSRNOT00000068040
ankyrin repeat and kinase domain containing 1
chr1_-_67134827 0.16 ENSRNOT00000045214
vomeronasal 1 receptor 45
chr3_+_77047466 0.16 ENSRNOT00000089424
olfactory receptor 648
chr7_-_114380613 0.14 ENSRNOT00000011898
argonaute 2, RISC catalytic component
chr16_+_81089292 0.13 ENSRNOT00000087192
ENSRNOT00000026150
transcription factor Dp-1

Network of associatons between targets according to the STRING database.

First level regulatory network of Sox17

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.6 25.5 GO:0007341 penetration of zona pellucida(GO:0007341)
3.6 21.7 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
3.0 15.0 GO:0035617 stress granule disassembly(GO:0035617)
2.6 10.4 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
1.9 15.3 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
1.3 6.4 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
1.2 12.4 GO:0006348 chromatin silencing at telomere(GO:0006348)
1.2 9.6 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
1.2 3.6 GO:0070175 positive regulation of enamel mineralization(GO:0070175)
1.2 37.9 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
1.1 5.7 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
1.1 57.8 GO:0003009 skeletal muscle contraction(GO:0003009)
1.1 11.0 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
1.0 10.7 GO:0030259 lipid glycosylation(GO:0030259)
0.8 4.0 GO:0000957 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.7 3.7 GO:0010626 negative regulation of Schwann cell proliferation(GO:0010626)
0.7 5.2 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.7 2.2 GO:0002215 defense response to nematode(GO:0002215)
0.7 5.4 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.6 2.5 GO:0035553 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.6 12.1 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.5 6.0 GO:0000338 protein deneddylation(GO:0000338)
0.5 4.8 GO:0050957 equilibrioception(GO:0050957)
0.5 3.7 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.5 12.5 GO:0003351 epithelial cilium movement(GO:0003351)
0.5 12.9 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.5 16.4 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.4 3.6 GO:2000210 positive regulation of anoikis(GO:2000210)
0.4 3.8 GO:0039532 negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway(GO:0039532) negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.4 6.9 GO:0001771 immunological synapse formation(GO:0001771)
0.4 25.4 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.4 1.4 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.4 1.4 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.3 5.2 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.3 3.1 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.3 2.4 GO:1900244 positive regulation of synaptic vesicle endocytosis(GO:1900244)
0.3 3.8 GO:0006241 CTP biosynthetic process(GO:0006241) CTP metabolic process(GO:0046036)
0.3 7.8 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.3 1.0 GO:0001692 histamine metabolic process(GO:0001692)
0.3 2.3 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.2 5.7 GO:0007020 microtubule nucleation(GO:0007020)
0.2 5.7 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.2 3.7 GO:0097503 sialylation(GO:0097503)
0.1 0.4 GO:0045425 regulation of interleukin-3 production(GO:0032672) positive regulation of interleukin-3 production(GO:0032752) interleukin-3 biosynthetic process(GO:0042223) regulation of interleukin-3 biosynthetic process(GO:0045399) positive regulation of interleukin-3 biosynthetic process(GO:0045401) positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425)
0.1 2.4 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.1 1.3 GO:0019372 lipoxygenase pathway(GO:0019372)
0.1 1.8 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.1 25.5 GO:0042742 defense response to bacterium(GO:0042742)
0.1 0.2 GO:0061642 chemoattraction of axon(GO:0061642)
0.1 6.0 GO:0009409 response to cold(GO:0009409)
0.1 7.1 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.1 0.2 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.1 1.1 GO:0035493 SNARE complex assembly(GO:0035493)
0.1 1.0 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.1 1.9 GO:0070207 protein homotrimerization(GO:0070207)
0.0 0.1 GO:0035087 siRNA loading onto RISC involved in RNA interference(GO:0035087)
0.0 6.6 GO:0009566 fertilization(GO:0009566)
0.0 3.8 GO:0007631 feeding behavior(GO:0007631)
0.0 1.3 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.0 1.7 GO:0006334 nucleosome assembly(GO:0006334)
0.0 3.6 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.0 1.7 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.0 0.1 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.0 0.9 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.0 3.1 GO:0007018 microtubule-based movement(GO:0007018)
0.0 0.8 GO:0071427 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 1.7 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.0 2.5 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 2.3 GO:0045665 negative regulation of neuron differentiation(GO:0045665)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
4.8 19.3 GO:0034774 secretory granule lumen(GO:0034774)
4.8 57.8 GO:0005861 troponin complex(GO:0005861)
1.6 11.1 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
1.3 6.4 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
1.3 16.4 GO:0005885 Arp2/3 protein complex(GO:0005885)
1.1 25.5 GO:0001673 male germ cell nucleus(GO:0001673)
0.6 5.2 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.5 7.5 GO:0043083 synaptic cleft(GO:0043083)
0.5 8.1 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.4 3.1 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.4 1.1 GO:0035577 azurophil granule membrane(GO:0035577) tertiary granule membrane(GO:0070821)
0.3 15.0 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.3 1.4 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.3 5.7 GO:0000930 gamma-tubulin complex(GO:0000930)
0.3 15.3 GO:0005637 nuclear inner membrane(GO:0005637)
0.2 5.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.2 17.3 GO:0045178 basal part of cell(GO:0045178)
0.2 4.0 GO:0005839 proteasome core complex(GO:0005839)
0.2 6.0 GO:0008180 COP9 signalosome(GO:0008180)
0.2 10.3 GO:0005643 nuclear pore(GO:0005643)
0.2 3.6 GO:0005605 basal lamina(GO:0005605)
0.1 19.0 GO:0005923 bicellular tight junction(GO:0005923)
0.1 12.9 GO:0016605 PML body(GO:0016605)
0.1 2.2 GO:0070822 Sin3-type complex(GO:0070822)
0.1 1.8 GO:0035371 centriolar satellite(GO:0034451) microtubule plus-end(GO:0035371)
0.1 4.6 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 10.2 GO:0030658 transport vesicle membrane(GO:0030658)
0.1 2.9 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 3.1 GO:0030286 dynein complex(GO:0030286)
0.1 3.7 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 3.8 GO:0031225 anchored component of membrane(GO:0031225)
0.0 3.0 GO:0045095 keratin filament(GO:0045095)
0.0 0.8 GO:0005686 U2 snRNP(GO:0005686)
0.0 4.0 GO:0036126 sperm flagellum(GO:0036126)
0.0 16.2 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 9.2 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 13.3 GO:0005813 centrosome(GO:0005813)
0.0 38.0 GO:0005615 extracellular space(GO:0005615)
0.0 10.2 GO:0043025 neuronal cell body(GO:0043025)
0.0 0.1 GO:0070578 micro-ribonucleoprotein complex(GO:0035068) RISC-loading complex(GO:0070578)
0.0 6.9 GO:0045202 synapse(GO:0045202)
0.0 1.9 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 34.1 GO:0005576 extracellular region(GO:0005576)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
12.1 60.7 GO:0005550 pheromone binding(GO:0005550)
5.1 20.5 GO:0030172 troponin C binding(GO:0030172) calcium-dependent ATPase activity(GO:0030899)
1.8 12.9 GO:0035375 zymogen binding(GO:0035375)
1.1 8.8 GO:0004565 beta-galactosidase activity(GO:0004565)
1.0 11.0 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.9 3.7 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.8 2.4 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.6 2.5 GO:0035514 DNA demethylase activity(GO:0035514) oxidative RNA demethylase activity(GO:0035515)
0.6 12.1 GO:0008327 methyl-CpG binding(GO:0008327)
0.5 3.1 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.5 37.3 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.5 12.5 GO:0004016 adenylate cyclase activity(GO:0004016)
0.3 14.6 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.3 1.7 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.3 8.1 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.3 1.3 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.2 11.1 GO:0008307 structural constituent of muscle(GO:0008307)
0.2 5.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.2 10.4 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.2 15.2 GO:0016503 pheromone receptor activity(GO:0016503)
0.2 18.6 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 4.0 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 7.0 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 7.8 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 5.7 GO:0070330 aromatase activity(GO:0070330)
0.1 1.4 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.1 4.0 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 4.3 GO:0051059 NF-kappaB binding(GO:0051059)
0.1 12.9 GO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191)
0.1 14.7 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 5.6 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.1 5.2 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.1 0.4 GO:0019767 IgE receptor activity(GO:0019767)
0.1 3.8 GO:0016879 ligase activity, forming carbon-nitrogen bonds(GO:0016879)
0.1 8.6 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.1 2.3 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.1 10.7 GO:0016758 transferase activity, transferring hexosyl groups(GO:0016758)
0.0 2.2 GO:0004601 peroxidase activity(GO:0004601)
0.0 5.2 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 3.1 GO:0003777 microtubule motor activity(GO:0003777)
0.0 3.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 9.6 GO:0005096 GTPase activator activity(GO:0005096)
0.0 1.1 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 1.9 GO:0043621 protein self-association(GO:0043621)
0.0 1.0 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.1 GO:0035197 siRNA binding(GO:0035197)
0.0 0.2 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 7.4 GO:0005549 odorant binding(GO:0005549)
0.0 0.9 GO:0008013 beta-catenin binding(GO:0008013)
0.0 4.6 GO:0003924 GTPase activity(GO:0003924)
0.0 0.2 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 1.4 GO:0004540 ribonuclease activity(GO:0004540)
0.0 19.7 GO:0003677 DNA binding(GO:0003677)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 6.9 PID AURORA A PATHWAY Aurora A signaling
0.2 6.4 PID AURORA B PATHWAY Aurora B signaling
0.1 5.7 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 5.2 PID ATR PATHWAY ATR signaling pathway
0.0 1.1 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.4 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 48.4 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.5 5.7 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.4 10.3 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.2 2.4 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.1 4.0 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.1 6.4 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 1.1 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 2.9 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 6.3 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.0 5.4 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.2 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs