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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Sox14

Z-value: 0.96

Motif logo

Transcription factors associated with Sox14

Gene Symbol Gene ID Gene Info
ENSRNOG00000022084 SRY box 14

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Sox14rn6_v1_chr8_-_108109801_1081098010.172.7e-03Click!

Activity profile of Sox14 motif

Sorted Z-values of Sox14 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr18_+_30562178 28.25 ENSRNOT00000040998
protocadherin beta-16-like
chr20_+_3422461 23.77 ENSRNOT00000084917
ENSRNOT00000079854
tubulin, beta 5 class I
chrX_+_39711201 22.76 ENSRNOT00000080512
ENSRNOT00000009802
connector enhancer of kinase suppressor of Ras 2
chr10_-_85974644 20.31 ENSRNOT00000006098
ENSRNOT00000082974
calcium voltage-gated channel auxiliary subunit beta 1
chr10_-_90393317 18.78 ENSRNOT00000028563
family with sequence similarity 171, member A2
chr2_-_96668222 18.13 ENSRNOT00000016567
cAMP-dependent protein kinase inhibitor alpha
chr1_-_170404056 17.74 ENSRNOT00000024402
amyloid beta precursor protein binding family B member 1
chr4_+_70572942 17.68 ENSRNOT00000051964

chr20_+_5049496 17.41 ENSRNOT00000088251
ENSRNOT00000001118
dimethylarginine dimethylaminohydrolase 2
chr1_-_236900904 16.93 ENSRNOT00000066846

chr5_+_152681101 16.44 ENSRNOT00000076052
ENSRNOT00000022574
stathmin 1
chr4_+_64088900 16.04 ENSRNOT00000075341
cholinergic receptor, muscarinic 2
chr15_+_52220578 15.61 ENSRNOT00000015104
leucine-rich repeat LGI family, member 3
chr7_+_116632506 15.51 ENSRNOT00000009811
glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1
chr3_-_104502471 15.49 ENSRNOT00000040306
ryanodine receptor 3
chr5_-_48165317 15.27 ENSRNOT00000088179
ankyrin repeat domain 6
chrX_+_28593405 14.99 ENSRNOT00000071708
thymosin beta 4, X-linked
chr1_+_264059374 14.79 ENSRNOT00000075397
stearoyl-Coenzyme A desaturase 2
chr12_+_48577905 14.45 ENSRNOT00000000888
selectin P ligand
chr1_-_225283326 14.13 ENSRNOT00000027342
secretoglobin family 1A member 1
chr10_+_55626741 14.11 ENSRNOT00000008492
aurora kinase B
chr7_-_136853957 14.08 ENSRNOT00000008985
neural EGFL like 2
chr12_-_5822874 14.01 ENSRNOT00000075920
FRY microtubule binding protein
chr8_-_65587427 13.96 ENSRNOT00000016491
leucine rich repeat containing 49
chrX_+_62727755 13.50 ENSRNOT00000077055
phosphate cytidylyltransferase 1, choline, beta
chr6_-_142903440 13.35 ENSRNOT00000075707

chr13_+_49850189 13.24 ENSRNOT00000042125
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
chr9_-_61810417 13.23 ENSRNOT00000020910
raftlin family member 2
chr2_-_111065413 13.00 ENSRNOT00000041111
neuroligin 1
chr1_+_192379543 12.98 ENSRNOT00000078705
protein kinase C, beta
chr6_-_41039437 12.95 ENSRNOT00000005774
tribbles pseudokinase 2
chr8_+_97291580 12.39 ENSRNOT00000018794
RAS protein-specific guanine nucleotide-releasing factor 1
chrX_+_106360393 12.31 ENSRNOT00000004260
G protein-coupled receptor associated sorting protein 2
chr1_+_59765835 12.20 ENSRNOT00000014842
formyl peptide receptor 1
chr18_+_30515962 12.19 ENSRNOT00000027172
protocadherin beta-6-like
chr19_+_24329544 12.15 ENSRNOT00000080934
TBC1 domain family member 9
chr13_+_47602692 12.10 ENSRNOT00000038822
Fc fragment of IgM receptor
chr18_+_29993361 12.01 ENSRNOT00000075810
protocadherin alpha 4
chr13_-_72789841 11.96 ENSRNOT00000004694
major histocompatibility complex, class I-related
chr13_-_45318822 11.89 ENSRNOT00000091514
ENSRNOT00000005143
C-X-C motif chemokine receptor 4
chr9_-_80167033 11.71 ENSRNOT00000023530
insulin-like growth factor binding protein 5
chr10_-_56167426 11.39 ENSRNOT00000013955
ephrin B3
chr11_+_61083757 11.29 ENSRNOT00000002790
BOC cell adhesion associated, oncogene regulated
chr15_+_41448064 11.19 ENSRNOT00000019551
sacsin molecular chaperone
chr5_-_20189721 11.17 ENSRNOT00000014661
thymocyte selection-associated high mobility group box
chr17_-_44840131 10.75 ENSRNOT00000083417
histone cluster 1, H3b
chr7_+_116355698 10.73 ENSRNOT00000076693
lymphocyte antigen 6 complex, locus E
chr8_+_23113048 10.60 ENSRNOT00000029577
calponin 1
chr1_-_228753422 10.53 ENSRNOT00000028626
deltex E3 ubiquitin ligase 4
chr14_-_2700977 10.46 ENSRNOT00000000086
metal response element binding transcription factor 2
chr14_-_82048251 10.44 ENSRNOT00000074734
N-acetyltransferase 8-like
chr18_+_55466373 10.35 ENSRNOT00000074629
interferon-inducible GTPase 1-like
chr6_+_132510757 10.35 ENSRNOT00000080230
Enah/Vasp-like
chr1_+_140601791 10.34 ENSRNOT00000091588
interferon stimulated exonuclease gene 20
chr14_+_77380262 10.31 ENSRNOT00000008030
neuron specific gene family member 1
chr7_+_116356324 10.18 ENSRNOT00000076407
ENSRNOT00000077022
ENSRNOT00000075873
lymphocyte antigen 6 complex, locus E
chr5_+_71742911 10.14 ENSRNOT00000047225
zinc finger protein 462
chr4_-_55011415 10.05 ENSRNOT00000056996
glutamate metabotropic receptor 8
chr1_-_190914610 10.03 ENSRNOT00000023189
cerebellar degeneration-related protein 2
chr6_-_142676432 9.96 ENSRNOT00000074947

chr15_-_108120279 9.88 ENSRNOT00000090572
dedicator of cytokinesis 9
chr8_-_80631873 9.85 ENSRNOT00000091661
ENSRNOT00000080662
unc-13 homolog C
chr18_+_30581530 9.76 ENSRNOT00000048166
protocadherin beta 20
chr20_+_6923489 9.74 ENSRNOT00000093373
ENSRNOT00000000632
peptidase inhibitor 16
chr18_+_55463308 9.72 ENSRNOT00000073388
interferon-inducible GTPase 1-like
chr3_+_35014538 9.70 ENSRNOT00000006341
kinesin family member 5C
chr2_-_96520137 9.68 ENSRNOT00000066966
zinc finger, C2HC-type containing 1A
chr5_+_172364421 9.59 ENSRNOT00000018769
hes family bHLH transcription factor 5
chr6_-_139142218 9.49 ENSRNOT00000006975
Immunoglobulin heavy chain (gamma polypeptide)
chr14_+_75880410 9.47 ENSRNOT00000014078
heparan sulfate-glucosamine 3-sulfotransferase 1
chr16_-_3765917 9.41 ENSRNOT00000088284
double homeobox B-like 1
chr17_+_53229785 9.33 ENSRNOT00000082040
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
chr1_-_67065797 9.17 ENSRNOT00000048152
vomeronasal 1 receptor 46
chr7_+_116355911 9.15 ENSRNOT00000076182
lymphocyte antigen 6 complex, locus E
chr6_-_54020406 9.11 ENSRNOT00000086038
histone deacetylase 9
chr12_+_38160464 9.04 ENSRNOT00000032249
hydroxycarboxylic acid receptor 2
chr17_+_70684340 9.03 ENSRNOT00000051067
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr9_-_113504605 9.00 ENSRNOT00000067974
RAB31, member RAS oncogene family
chr8_-_65587658 8.97 ENSRNOT00000091982
leucine rich repeat containing 49
chr2_-_30458542 8.95 ENSRNOT00000072926
NLR family, apoptosis inhibitory protein 6
chr6_+_137164535 8.93 ENSRNOT00000018225
inverted formin, FH2 and WH2 domain containing
chr7_-_50638798 8.84 ENSRNOT00000048880
synaptotagmin 1
chr2_+_226900619 8.81 ENSRNOT00000019638
phosphodiesterase 5A
chr13_+_52854031 8.61 ENSRNOT00000013738
ENSRNOT00000086004
transmembrane protein 9
chr7_+_116356163 8.52 ENSRNOT00000076412
ENSRNOT00000009333
lymphocyte antigen 6 complex, locus E
chr18_+_30527705 8.47 ENSRNOT00000027168
protocadherin beta 14
chr1_-_219438779 8.45 ENSRNOT00000029237
TBC1 domain family, member 10C
chr2_-_210282352 8.28 ENSRNOT00000075653
solute carrier family 6 member 17
chr18_+_30509393 8.26 ENSRNOT00000043846
protocadherin beta 12
chr12_+_25173005 8.20 ENSRNOT00000033200
ENSRNOT00000091328
CAP-GLY domain containing linker protein 2
chr1_-_101236065 8.09 ENSRNOT00000066834
CD37 molecule
chr1_+_81230612 8.08 ENSRNOT00000026489
potassium calcium-activated channel subfamily N member 4
chr4_+_78694447 8.07 ENSRNOT00000011945
glycoprotein nmb
chr7_-_136853154 8.06 ENSRNOT00000087376
neural EGFL like 2
chr17_-_43627629 8.06 ENSRNOT00000022965
histone cluster 1, H2af
chr5_-_173233188 8.04 ENSRNOT00000055343
transmembrane protein 88B
chr18_+_30435119 8.03 ENSRNOT00000027190
protocadherin beta 8
chrX_+_15113878 8.00 ENSRNOT00000007464
WD repeat domain 13
chr18_+_30381322 7.99 ENSRNOT00000027216
protocadherin beta 3
chr16_-_6675746 7.98 ENSRNOT00000025858
protein kinase C, delta
chr3_+_16817051 7.96 ENSRNOT00000071666

chr2_+_72006099 7.93 ENSRNOT00000034044
cadherin 12
chr18_+_15467870 7.89 ENSRNOT00000091696
beta-1,4-galactosyltransferase 6
chr18_+_55391388 7.85 ENSRNOT00000071612
interferon-inducible GTPase 1-like
chr7_-_63407241 7.85 ENSRNOT00000024679
TBC1 domain family, member 30
chr7_+_141346398 7.84 ENSRNOT00000077175
acid sensing ion channel subunit 1
chr10_+_44271587 7.80 ENSRNOT00000047700
tripartite motif-containing 58
chr6_+_8669722 7.75 ENSRNOT00000048550
calmodulin-lysine N-methyltransferase
chr10_+_55627025 7.71 ENSRNOT00000091016
aurora kinase B
chr20_+_13670066 7.69 ENSRNOT00000031400
stromelysin-3
chr18_+_55505993 7.64 ENSRNOT00000043736
similar to interferon-inducible GTPase
chr16_-_19399851 7.64 ENSRNOT00000089056
ENSRNOT00000021073
tropomyosin 4
chr9_+_6970507 7.63 ENSRNOT00000079488
ST6 beta-galactoside alpha-2,6-sialyltransferase 2
chr18_+_29966245 7.51 ENSRNOT00000074028
protocadherin alpha 4
chr7_-_12275609 7.45 ENSRNOT00000086061
APC2, WNT signaling pathway regulator
chr1_-_82004538 7.39 ENSRNOT00000087572
POU class 2 homeobox 2
chr4_+_21317695 7.36 ENSRNOT00000007572
glutamate metabotropic receptor 3
chr2_-_23909016 7.34 ENSRNOT00000084044
secretory carrier membrane protein 1
chr2_-_183213228 7.29 ENSRNOT00000067618
tripartite motif-containing 2
chr2_+_178679041 7.25 ENSRNOT00000013524
family with sequence similarity 198, member B
chr14_+_81837809 7.20 ENSRNOT00000020576
HAUS augmin-like complex, subunit 3
chr11_+_30550141 7.20 ENSRNOT00000002866
hormonally upregulated Neu-associated kinase
chr6_+_100337226 7.10 ENSRNOT00000011220
fucosyltransferase 8
chr4_-_165541314 7.09 ENSRNOT00000013833
serine/threonine/tyrosine kinase 1
chr5_-_90282327 7.09 ENSRNOT00000065792
FERM domain containing 3
chr4_+_179398621 7.04 ENSRNOT00000049474
ENSRNOT00000067506
lymphoid-restricted membrane protein
chr6_-_42473738 6.93 ENSRNOT00000033327
potassium voltage-gated channel modifier subfamily F member 1
chr1_+_81373340 6.90 ENSRNOT00000026814
zinc finger protein 428
chr10_+_35870682 6.82 ENSRNOT00000067188
heterogeneous nuclear ribonucleoprotein H1
chr14_+_7618022 6.73 ENSRNOT00000088508
ENSRNOT00000002819
solute carrier family 10 member 6
chr3_-_146690375 6.68 ENSRNOT00000010641
abhydrolase domain containing 12
chr20_+_3553455 6.68 ENSRNOT00000090080
discoidin domain receptor tyrosine kinase 1
chr2_-_198002625 6.68 ENSRNOT00000091888
cDNA sequence BC028528
chr3_-_148932878 6.66 ENSRNOT00000013881
nucleolar protein 4-like
chr16_-_74122889 6.58 ENSRNOT00000025763
plasminogen activator, tissue type
chr8_+_63379087 6.56 ENSRNOT00000012091
ENSRNOT00000012295
neuroplastin
chr16_+_23553647 6.52 ENSRNOT00000041994
pleckstrin and Sec7 domain containing 3
chr1_+_64928503 6.41 ENSRNOT00000086274
vomeronasal 2 receptor, 80
chr12_-_22211071 6.40 ENSRNOT00000087817
ENSRNOT00000001910
actin-like 6B
chr4_-_77706994 6.32 ENSRNOT00000038517
zinc finger protein 777
chrX_+_156909913 6.30 ENSRNOT00000084390
L1 cell adhesion molecule
chr6_-_2316717 6.26 ENSRNOT00000082017
ENSRNOT00000066363
cytochrome P450, family 1, subfamily b, polypeptide 1
chr15_-_28733513 6.25 ENSRNOT00000078180
spalt-like transcription factor 2
chr17_+_70684539 6.23 ENSRNOT00000025700
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr18_+_29972808 6.18 ENSRNOT00000074051
protocadherin alpha 4
chr6_-_141008427 6.17 ENSRNOT00000074472

chr14_-_35149608 6.06 ENSRNOT00000003050
ENSRNOT00000090654
KIT proto-oncogene receptor tyrosine kinase
chr6_-_55647665 6.04 ENSRNOT00000007414
basic leucine zipper and W2 domains 2
chr10_+_43542697 6.03 ENSRNOT00000003555
CCR4-NOT transcription complex, subunit 8
chr4_+_69457472 6.00 ENSRNOT00000067597
T cell receptor beta, variable 19
chr4_+_102262007 5.93 ENSRNOT00000079328

chr9_+_46657922 5.92 ENSRNOT00000019180
mitogen-activated protein kinase kinase kinase kinase 4
chr18_+_30895831 5.92 ENSRNOT00000026985
protocadherin gamma subfamily A, 10
chr13_+_60435946 5.91 ENSRNOT00000004342
Beta-1,3-galactosyltransferase 2
chr6_-_61405195 5.88 ENSRNOT00000008655
leucine rich repeat neuronal 3
chr7_+_14643704 5.87 ENSRNOT00000044642

chr5_+_145188323 5.85 ENSRNOT00000038888
transmembrane protein 35B
chr6_+_55648021 5.83 ENSRNOT00000064822
ENSRNOT00000091488
ankyrin repeat and MYND domain containing 2
chr10_-_34439470 5.66 ENSRNOT00000072081
butyrophilin-like 9
chr4_-_164211819 5.59 ENSRNOT00000084796
hypothetical protein LOC497796
chr16_-_81912738 5.55 ENSRNOT00000087095
MCF.2 cell line derived transforming sequence-like
chrX_+_105402867 5.55 ENSRNOT00000057222
ribosomal protein L36a
chr3_+_19366370 5.51 ENSRNOT00000086557

chr2_+_212435728 5.49 ENSRNOT00000046960

chr14_+_46001849 5.49 ENSRNOT00000076611
RELT-like 1
chr20_+_42966140 5.47 ENSRNOT00000000707
myristoylated alanine rich protein kinase C substrate
chr11_+_34598492 5.47 ENSRNOT00000065600
tetratricopeptide repeat domain 3
chr10_-_15125408 5.47 ENSRNOT00000026395
mesothelin
chr9_+_73334618 5.45 ENSRNOT00000092717
microtubule-associated protein 2
chr5_-_158549496 5.45 ENSRNOT00000074336
immunoglobin superfamily, member 21
chr3_+_100787449 5.40 ENSRNOT00000078543
brain-derived neurotrophic factor
chr1_+_101687855 5.36 ENSRNOT00000028546
ENSRNOT00000091597
D-box binding PAR bZIP transcription factor
chr2_+_38230757 5.35 ENSRNOT00000048598
similar to 60S ribosomal protein L23a
chr16_+_83206004 5.28 ENSRNOT00000018870
ankyrin repeat domain 10
chr6_+_55374984 5.28 ENSRNOT00000091682
anterior gradient 3, protein disulphide isomerase family member
chr8_+_5606592 5.20 ENSRNOT00000011727
matrix metallopeptidase 12
chr13_-_91776397 5.17 ENSRNOT00000073147
mucosal pentraxin 1
chr19_+_38601786 5.10 ENSRNOT00000087655
zinc finger protein 90
chr1_+_87655618 5.06 ENSRNOT00000035994
ENSRNOT00000073521
zinc finger protein 84
chr1_+_177093387 5.04 ENSRNOT00000021858
microtubule associated monooxygenase, calponin and LIM domain containing 2
chr1_+_213040024 5.03 ENSRNOT00000050237
olfactory receptor 300
chr7_-_114380613 4.97 ENSRNOT00000011898
argonaute 2, RISC catalytic component
chr13_+_49870976 4.95 ENSRNOT00000090170
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
chr7_-_117880289 4.93 ENSRNOT00000052227
Rho GTPase activating protein 39
chr10_-_35187416 4.93 ENSRNOT00000084509
CCR4-NOT transcription complex, subunit 6
chr3_-_152159749 4.92 ENSRNOT00000067490
copine 1
chr7_-_120874308 4.90 ENSRNOT00000078320
family with sequence similarity 227, member A
chr6_-_138909105 4.87 ENSRNOT00000087855

chr10_-_66602987 4.85 ENSRNOT00000017949
WD repeat and SOCS box-containing 1
chr10_-_110101872 4.83 ENSRNOT00000071893
coiled-coil domain containing 57
chr11_+_64761146 4.83 ENSRNOT00000051428
protein O-glucosyltransferase 1
chr3_+_18787606 4.79 ENSRNOT00000090508

chr16_-_22561496 4.77 ENSRNOT00000016543
lipoprotein lipase
chr11_+_45751812 4.72 ENSRNOT00000079336
similar to Dermal papilla derived protein 7
chr1_-_265792932 4.68 ENSRNOT00000040904
LIM domain binding 1
chr4_+_176606649 4.68 ENSRNOT00000084700
golgi transport 1B
chr1_+_72230038 4.65 ENSRNOT00000058997
vomeronasal 1 receptor 38
chr20_+_6288267 4.55 ENSRNOT00000000627
serine and arginine rich splicing factor 3
chr1_-_59802401 4.49 ENSRNOT00000064917
formyl peptide receptor 2
chr3_-_23474170 4.48 ENSRNOT00000039410
suppressor of cancer cell invasion

Network of associatons between targets according to the STRING database.

First level regulatory network of Sox14

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
5.5 21.8 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
5.2 15.5 GO:0010986 positive regulation of lipoprotein particle clearance(GO:0010986)
4.3 13.0 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
4.1 16.4 GO:0070495 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
3.5 14.1 GO:0032696 negative regulation of interleukin-13 production(GO:0032696)
3.5 14.0 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
3.4 10.3 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
3.2 13.0 GO:0098923 retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by trans-synaptic complex(GO:0099545)
3.2 12.9 GO:0045074 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
3.2 16.0 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
3.2 9.6 GO:2000974 auditory receptor cell fate determination(GO:0042668) negative regulation of pro-B cell differentiation(GO:2000974) negative regulation of forebrain neuron differentiation(GO:2000978)
3.2 9.5 GO:0001788 antibody-dependent cellular cytotoxicity(GO:0001788)
3.0 11.9 GO:1990478 positive regulation of vascular wound healing(GO:0035470) response to ultrasound(GO:1990478)
2.9 11.7 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
2.8 8.3 GO:0015820 leucine transport(GO:0015820)
2.7 8.0 GO:0060697 positive regulation of phospholipid catabolic process(GO:0060697)
2.6 10.5 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
2.6 10.4 GO:0051582 positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
2.5 7.4 GO:0002380 immunoglobulin secretion involved in immune response(GO:0002380)
2.4 9.7 GO:0098964 dendritic transport of ribonucleoprotein complex(GO:0098961) dendritic transport of messenger ribonucleoprotein complex(GO:0098963) anterograde dendritic transport of messenger ribonucleoprotein complex(GO:0098964)
2.3 38.6 GO:0048242 epinephrine secretion(GO:0048242)
2.2 13.2 GO:0033227 dsRNA transport(GO:0033227)
2.1 15.0 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
2.1 21.4 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
2.1 6.3 GO:0071387 cellular response to cortisol stimulus(GO:0071387)
2.0 8.1 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
1.8 22.1 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
1.8 5.5 GO:1901726 negative regulation of histone deacetylase activity(GO:1901726)
1.8 7.1 GO:0046368 GDP-L-fucose metabolic process(GO:0046368)
1.8 8.8 GO:0060282 negative regulation of cardiac muscle contraction(GO:0055118) positive regulation of oocyte development(GO:0060282)
1.7 10.4 GO:1904387 cellular response to L-phenylalanine derivative(GO:1904387)
1.7 5.2 GO:1902739 type I interferon secretion(GO:0072641) interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741)
1.7 10.3 GO:0098887 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887)
1.7 8.4 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
1.7 5.0 GO:0019417 sulfur oxidation(GO:0019417)
1.7 6.7 GO:0052651 monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
1.6 6.6 GO:0060279 positive regulation of ovulation(GO:0060279)
1.6 4.9 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
1.6 6.6 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
1.6 17.4 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
1.6 3.1 GO:1904339 negative regulation of dopaminergic neuron differentiation(GO:1904339)
1.5 15.3 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
1.5 6.1 GO:0097324 Kit signaling pathway(GO:0038109) melanocyte migration(GO:0097324) positive regulation of vascular smooth muscle cell differentiation(GO:1905065)
1.5 18.1 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
1.5 13.5 GO:1904116 response to vasopressin(GO:1904116)
1.5 10.5 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
1.3 13.5 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
1.3 10.6 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
1.3 9.1 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
1.3 9.0 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
1.3 9.0 GO:0070269 pyroptosis(GO:0070269)
1.3 15.3 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
1.3 3.8 GO:0007161 calcium-independent cell-matrix adhesion(GO:0007161)
1.2 5.0 GO:0035087 siRNA loading onto RISC involved in RNA interference(GO:0035087) mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
1.2 9.7 GO:0061052 negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
1.2 4.7 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
1.1 11.4 GO:0016198 axon choice point recognition(GO:0016198)
1.1 18.2 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
1.1 7.8 GO:0050915 sensory perception of sour taste(GO:0050915)
1.1 17.4 GO:0000052 citrulline metabolic process(GO:0000052)
1.1 8.6 GO:0061193 taste bud development(GO:0061193)
1.1 5.3 GO:2000791 regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584) regulation of mesenchymal cell proliferation involved in lung development(GO:2000790) negative regulation of mesenchymal cell proliferation involved in lung development(GO:2000791)
1.0 11.2 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
1.0 3.0 GO:0045077 negative regulation of interferon-gamma biosynthetic process(GO:0045077)
1.0 4.0 GO:0042339 keratan sulfate metabolic process(GO:0042339)
1.0 11.0 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
1.0 7.9 GO:0022007 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
1.0 10.7 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
1.0 4.8 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
1.0 3.8 GO:0002913 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
1.0 3.8 GO:0060398 regulation of growth hormone receptor signaling pathway(GO:0060398)
0.9 2.8 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.9 3.7 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.9 5.5 GO:1900019 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.9 9.9 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.9 10.3 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.9 3.4 GO:0030581 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.8 3.3 GO:0021747 cochlear nucleus development(GO:0021747)
0.8 3.3 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.8 2.4 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350) nuclear retention of pre-mRNA at the site of transcription(GO:0071033)
0.8 4.8 GO:0055095 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)
0.8 8.7 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.8 12.4 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.8 109.4 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.8 27.7 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.7 3.7 GO:1902473 regulation of protein localization to synapse(GO:1902473)
0.7 8.1 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.7 4.3 GO:2001025 positive regulation of response to drug(GO:2001025)
0.7 2.8 GO:1904925 positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.7 2.8 GO:0045829 negative regulation of isotype switching(GO:0045829)
0.7 6.7 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.7 7.9 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.7 3.3 GO:1903142 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.6 8.8 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.6 8.0 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.6 6.1 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.6 1.7 GO:0045401 regulation of interleukin-3 production(GO:0032672) positive regulation of interleukin-3 production(GO:0032752) interleukin-3 biosynthetic process(GO:0042223) regulation of interleukin-3 biosynthetic process(GO:0045399) positive regulation of interleukin-3 biosynthetic process(GO:0045401) positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425)
0.6 3.9 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.6 2.2 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.6 4.4 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.5 20.3 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.5 7.9 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
0.5 14.4 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.5 2.0 GO:0061641 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.5 12.1 GO:0051481 negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.5 9.0 GO:0090382 phagosome maturation(GO:0090382)
0.5 2.0 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.5 1.0 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.5 2.4 GO:0035822 meiotic gene conversion(GO:0006311) gene conversion(GO:0035822)
0.5 6.1 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.5 1.9 GO:0009597 detection of virus(GO:0009597)
0.5 2.8 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.4 12.0 GO:0032620 interleukin-17 production(GO:0032620)
0.4 3.3 GO:0035635 exocyst assembly(GO:0001927) entry of bacterium into host cell(GO:0035635) regulation of entry of bacterium into host cell(GO:2000535)
0.4 15.8 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.4 11.3 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.4 4.4 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.4 6.3 GO:0097503 sialylation(GO:0097503)
0.3 7.2 GO:0030574 collagen catabolic process(GO:0030574)
0.3 2.4 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.3 8.9 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.3 16.0 GO:0043392 negative regulation of DNA binding(GO:0043392)
0.3 28.9 GO:0051225 spindle assembly(GO:0051225)
0.3 17.7 GO:0008542 visual learning(GO:0008542)
0.3 1.2 GO:0019064 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.3 8.1 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.3 4.5 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.3 3.2 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.3 0.8 GO:0042245 RNA repair(GO:0042245)
0.3 1.9 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501) negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.3 6.5 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.3 0.8 GO:0090669 telomerase RNA stabilization(GO:0090669)
0.2 1.7 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.2 3.1 GO:0051764 actin crosslink formation(GO:0051764)
0.2 2.2 GO:0002087 regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.2 0.7 GO:0016094 polyprenol biosynthetic process(GO:0016094) ketone body catabolic process(GO:0046952)
0.2 3.5 GO:0043584 nose development(GO:0043584)
0.2 2.8 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895)
0.2 0.7 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.2 7.1 GO:0033006 regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304)
0.2 3.4 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.2 1.2 GO:2000354 regulation of ovarian follicle development(GO:2000354)
0.2 2.0 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.2 5.3 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.2 2.4 GO:0048199 vesicle targeting, to, from or within Golgi(GO:0048199)
0.2 1.2 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.2 2.7 GO:0021819 layer formation in cerebral cortex(GO:0021819)
0.2 5.6 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.2 4.2 GO:0006198 cAMP catabolic process(GO:0006198)
0.2 2.3 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090)
0.2 3.8 GO:0008340 determination of adult lifespan(GO:0008340)
0.2 3.4 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.2 0.5 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.2 3.4 GO:0034453 microtubule anchoring(GO:0034453)
0.1 2.6 GO:0097435 fibril organization(GO:0097435)
0.1 4.9 GO:0060325 face morphogenesis(GO:0060325)
0.1 2.1 GO:0032674 regulation of interleukin-5 production(GO:0032674)
0.1 2.3 GO:0035855 megakaryocyte development(GO:0035855)
0.1 0.9 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
0.1 2.9 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.1 2.2 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.1 3.7 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.1 1.7 GO:0003334 keratinocyte development(GO:0003334)
0.1 0.6 GO:0070102 interleukin-6-mediated signaling pathway(GO:0070102)
0.1 7.9 GO:0034763 negative regulation of transmembrane transport(GO:0034763)
0.1 0.6 GO:0006621 protein retention in ER lumen(GO:0006621)
0.1 5.1 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.1 0.8 GO:1904424 regulation of GTP binding(GO:1904424)
0.1 15.6 GO:0017157 regulation of exocytosis(GO:0017157)
0.1 5.9 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.1 0.5 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.1 1.4 GO:0001675 acrosome assembly(GO:0001675)
0.1 0.9 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.1 2.4 GO:0030488 tRNA methylation(GO:0030488)
0.1 2.1 GO:0006376 mRNA splice site selection(GO:0006376)
0.1 1.9 GO:0051205 protein insertion into membrane(GO:0051205)
0.1 3.5 GO:0001893 maternal placenta development(GO:0001893)
0.1 5.8 GO:0008589 regulation of smoothened signaling pathway(GO:0008589)
0.1 0.5 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.1 0.1 GO:1904637 response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
0.1 0.8 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.1 7.8 GO:0018022 peptidyl-lysine methylation(GO:0018022)
0.1 5.9 GO:0010771 negative regulation of cell morphogenesis involved in differentiation(GO:0010771)
0.1 1.1 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.1 0.2 GO:0002084 protein depalmitoylation(GO:0002084)
0.1 0.9 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0 9.2 GO:0043523 regulation of neuron apoptotic process(GO:0043523)
0.0 7.6 GO:0001649 osteoblast differentiation(GO:0001649)
0.0 2.7 GO:0046323 glucose import(GO:0046323)
0.0 0.7 GO:0050691 regulation of defense response to virus by host(GO:0050691)
0.0 1.0 GO:0002228 natural killer cell mediated immunity(GO:0002228)
0.0 1.3 GO:0070613 regulation of protein processing(GO:0070613)
0.0 2.3 GO:0000724 double-strand break repair via homologous recombination(GO:0000724)
0.0 1.1 GO:0006342 chromatin silencing(GO:0006342)
0.0 2.3 GO:0001764 neuron migration(GO:0001764)
0.0 1.2 GO:0031016 pancreas development(GO:0031016)
0.0 3.8 GO:0071805 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0 1.0 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.9 GO:0006338 chromatin remodeling(GO:0006338)
0.0 1.1 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 1.4 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
4.4 17.7 GO:1990812 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
3.6 21.8 GO:0032133 chromosome passenger complex(GO:0032133)
2.7 16.0 GO:0032280 symmetric synapse(GO:0032280)
2.6 23.8 GO:0005641 nuclear envelope lumen(GO:0005641)
2.4 9.5 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
2.1 10.3 GO:0098845 postsynaptic endosome(GO:0098845)
2.0 11.7 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
1.8 5.5 GO:0042585 germinal vesicle(GO:0042585)
1.8 9.0 GO:0072557 IPAF inflammasome complex(GO:0072557)
1.7 15.5 GO:0030314 junctional membrane complex(GO:0030314)
1.5 8.8 GO:0042584 chromaffin granule membrane(GO:0042584)
1.4 4.1 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
1.3 3.8 GO:0034666 integrin alpha2-beta1 complex(GO:0034666) integrin alpha3-beta1 complex(GO:0034667)
1.2 9.9 GO:0044305 calyx of Held(GO:0044305)
1.0 14.4 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.9 2.8 GO:0060187 cell pole(GO:0060187)
0.9 6.5 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.9 16.7 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.9 4.3 GO:0043293 apoptosome(GO:0043293)
0.8 9.5 GO:0005796 Golgi lumen(GO:0005796)
0.8 17.2 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.8 13.0 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.7 12.0 GO:0042612 MHC class I protein complex(GO:0042612)
0.7 7.2 GO:0070652 HAUS complex(GO:0070652)
0.7 5.0 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.7 3.5 GO:0005879 axonemal microtubule(GO:0005879)
0.7 9.7 GO:0035253 ciliary rootlet(GO:0035253)
0.7 2.7 GO:0097196 Shu complex(GO:0097196)
0.6 5.5 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.6 5.5 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.6 8.6 GO:0030061 mitochondrial crista(GO:0030061)
0.6 7.5 GO:0016342 catenin complex(GO:0016342)
0.6 6.3 GO:0044294 dendritic growth cone(GO:0044294)
0.6 3.9 GO:0001651 dense fibrillar component(GO:0001651)
0.6 2.8 GO:0032059 bleb(GO:0032059)
0.5 2.1 GO:0031592 centrosomal corona(GO:0031592)
0.5 8.4 GO:0042589 zymogen granule membrane(GO:0042589)
0.5 10.5 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.5 16.7 GO:0044295 axonal growth cone(GO:0044295)
0.5 8.4 GO:0031527 filopodium membrane(GO:0031527)
0.5 10.4 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.5 8.9 GO:0030014 CCR4-NOT complex(GO:0030014)
0.5 7.4 GO:0097449 astrocyte projection(GO:0097449)
0.5 6.4 GO:0016514 SWI/SNF complex(GO:0016514)
0.4 4.3 GO:1990635 proximal dendrite(GO:1990635)
0.4 11.3 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.4 2.8 GO:0031415 NatA complex(GO:0031415)
0.4 8.2 GO:0042599 lamellar body(GO:0042599)
0.4 4.8 GO:0042627 chylomicron(GO:0042627)
0.4 10.4 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.3 20.3 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.3 3.3 GO:0008290 F-actin capping protein complex(GO:0008290)
0.3 3.2 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.3 20.5 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.3 2.4 GO:0000815 ESCRT III complex(GO:0000815)
0.2 2.0 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.2 2.6 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.2 6.1 GO:0042629 mast cell granule(GO:0042629)
0.2 8.1 GO:0001772 immunological synapse(GO:0001772)
0.2 3.4 GO:0043657 host(GO:0018995) host cell(GO:0043657)
0.2 11.6 GO:0015030 Cajal body(GO:0015030)
0.2 2.4 GO:0000801 central element(GO:0000801)
0.2 0.4 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.2 5.9 GO:0030131 clathrin adaptor complex(GO:0030131)
0.2 3.3 GO:0010369 chromocenter(GO:0010369)
0.2 13.7 GO:0000118 histone deacetylase complex(GO:0000118)
0.2 16.6 GO:0042734 presynaptic membrane(GO:0042734)
0.2 3.3 GO:0005640 nuclear outer membrane(GO:0005640)
0.2 29.0 GO:0030427 site of polarized growth(GO:0030427)
0.1 2.4 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.1 22.0 GO:0043204 perikaryon(GO:0043204)
0.1 2.1 GO:0071004 U2-type prespliceosome(GO:0071004)
0.1 10.1 GO:0031526 brush border membrane(GO:0031526)
0.1 7.4 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 0.5 GO:0005607 laminin-1 complex(GO:0005606) laminin-2 complex(GO:0005607) laminin-10 complex(GO:0043259)
0.1 11.8 GO:0000786 nucleosome(GO:0000786)
0.1 2.1 GO:0008328 ionotropic glutamate receptor complex(GO:0008328) AMPA glutamate receptor complex(GO:0032281) neurotransmitter receptor complex(GO:0098878)
0.1 0.9 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1 10.9 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 0.7 GO:0034385 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.1 1.0 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 8.0 GO:0016363 nuclear matrix(GO:0016363)
0.1 80.2 GO:0005887 integral component of plasma membrane(GO:0005887)
0.1 15.4 GO:0045211 postsynaptic membrane(GO:0045211)
0.1 6.9 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.1 8.1 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.1 26.6 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.1 5.5 GO:0031225 anchored component of membrane(GO:0031225)
0.1 7.1 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.1 24.9 GO:0005925 focal adhesion(GO:0005925)
0.1 7.0 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.1 19.1 GO:0016607 nuclear speck(GO:0016607)
0.1 7.9 GO:0036064 ciliary basal body(GO:0036064)
0.1 2.0 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.1 9.0 GO:0005874 microtubule(GO:0005874)
0.0 5.6 GO:0008021 synaptic vesicle(GO:0008021)
0.0 14.8 GO:0000139 Golgi membrane(GO:0000139)
0.0 0.8 GO:0030904 retromer complex(GO:0030904)
0.0 20.3 GO:0005815 microtubule organizing center(GO:0005815)
0.0 0.9 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 1.9 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 12.4 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.9 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 5.5 GO:0015630 microtubule cytoskeleton(GO:0015630)
0.0 4.5 GO:0000790 nuclear chromatin(GO:0000790)
0.0 0.5 GO:0016592 mediator complex(GO:0016592)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
5.8 17.4 GO:0016403 dimethylargininase activity(GO:0016403)
5.3 16.0 GO:1990763 arrestin family protein binding(GO:1990763)
4.3 13.0 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
3.9 15.5 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
3.6 21.4 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
2.8 14.1 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
2.8 38.6 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
2.7 13.5 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
2.7 8.0 GO:0070976 TIR domain binding(GO:0070976)
2.6 10.5 GO:0032896 stearoyl-CoA 9-desaturase activity(GO:0004768) palmitoyl-CoA 9-desaturase activity(GO:0032896)
2.6 7.8 GO:0044736 acid-sensing ion channel activity(GO:0044736)
2.6 15.5 GO:0035473 lipase binding(GO:0035473)
2.6 10.2 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
2.5 10.1 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
2.5 7.4 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
2.3 18.2 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
2.1 10.3 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
2.0 11.9 GO:0032027 myosin light chain binding(GO:0032027)
2.0 7.9 GO:0008489 UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity(GO:0008489)
1.8 8.8 GO:0030348 syntaxin-3 binding(GO:0030348)
1.7 10.3 GO:0032051 clathrin light chain binding(GO:0032051)
1.6 4.8 GO:0030158 protein xylosyltransferase activity(GO:0030158)
1.6 9.5 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
1.5 18.1 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
1.4 15.3 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
1.3 6.6 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
1.3 3.9 GO:0034512 box C/D snoRNA binding(GO:0034512)
1.3 11.7 GO:0031995 insulin-like growth factor II binding(GO:0031995)
1.2 19.9 GO:0035174 histone serine kinase activity(GO:0035174)
1.2 8.7 GO:0004111 creatine kinase activity(GO:0004111)
1.2 3.7 GO:0052723 inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
1.2 23.8 GO:0032794 GTPase activating protein binding(GO:0032794)
1.2 5.9 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
1.2 8.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
1.1 9.9 GO:0019992 diacylglycerol binding(GO:0019992)
1.1 8.6 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
1.1 20.3 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
1.0 8.1 GO:0045545 syndecan binding(GO:0045545)
1.0 13.0 GO:0042043 neurexin family protein binding(GO:0042043)
1.0 9.7 GO:0034190 apolipoprotein receptor binding(GO:0034190)
1.0 6.7 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.9 3.7 GO:0099609 microtubule lateral binding(GO:0099609)
0.9 5.5 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.9 31.4 GO:0001540 beta-amyloid binding(GO:0001540)
0.8 2.4 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.8 9.5 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.8 6.1 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.8 3.8 GO:0098639 C-X3-C chemokine binding(GO:0019960) collagen binding involved in cell-matrix adhesion(GO:0098639)
0.7 2.2 GO:0008481 sphinganine kinase activity(GO:0008481)
0.7 9.1 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.7 2.8 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.7 12.9 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.7 4.0 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.6 10.9 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.6 8.8 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.6 5.0 GO:0035197 siRNA binding(GO:0035197)
0.6 10.3 GO:0005522 profilin binding(GO:0005522)
0.6 2.4 GO:0016426 tRNA (adenine) methyltransferase activity(GO:0016426)
0.6 7.1 GO:0008417 fucosyltransferase activity(GO:0008417)
0.6 4.7 GO:0030274 LIM domain binding(GO:0030274)
0.6 12.8 GO:0002162 dystroglycan binding(GO:0002162)
0.5 6.3 GO:0033691 sialic acid binding(GO:0033691)
0.5 3.1 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.5 4.1 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.5 6.7 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.5 8.2 GO:0051010 microtubule plus-end binding(GO:0051010)
0.5 4.6 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.5 15.0 GO:0003785 actin monomer binding(GO:0003785)
0.5 27.6 GO:0005080 protein kinase C binding(GO:0005080)
0.5 2.8 GO:0019158 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.4 3.1 GO:0043237 laminin-1 binding(GO:0043237)
0.4 1.7 GO:0019863 IgE binding(GO:0019863)
0.4 2.1 GO:0050733 RS domain binding(GO:0050733)
0.4 9.0 GO:0001614 purinergic nucleotide receptor activity(GO:0001614) nucleotide receptor activity(GO:0016502)
0.4 4.4 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.4 1.2 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.4 1.9 GO:0031849 olfactory receptor binding(GO:0031849)
0.4 2.9 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.3 1.0 GO:0023030 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.3 11.4 GO:0046875 ephrin receptor binding(GO:0046875)
0.3 4.8 GO:0034185 apolipoprotein binding(GO:0034185)
0.3 4.2 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.3 5.5 GO:0070628 proteasome binding(GO:0070628)
0.3 2.0 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.3 16.2 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.3 0.8 GO:1990460 leptin receptor binding(GO:1990460)
0.3 6.5 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.3 8.0 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.2 2.2 GO:0034056 estrogen response element binding(GO:0034056)
0.2 0.7 GO:0016453 C-acetyltransferase activity(GO:0016453)
0.2 2.8 GO:0016004 phospholipase activator activity(GO:0016004)
0.2 3.3 GO:0017160 Ral GTPase binding(GO:0017160)
0.2 12.5 GO:0016278 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.2 0.8 GO:0035515 DNA demethylase activity(GO:0035514) oxidative RNA demethylase activity(GO:0035515)
0.2 9.2 GO:0030331 estrogen receptor binding(GO:0030331)
0.2 5.0 GO:0071949 FAD binding(GO:0071949)
0.2 2.8 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.2 1.2 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.2 19.5 GO:0016503 pheromone receptor activity(GO:0016503)
0.2 4.1 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.2 6.5 GO:0008307 structural constituent of muscle(GO:0008307)
0.2 2.7 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.2 4.0 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.2 6.8 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.2 4.9 GO:0051059 NF-kappaB binding(GO:0051059)
0.2 1.9 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.2 1.1 GO:0035375 zymogen binding(GO:0035375)
0.1 7.1 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 9.0 GO:0019003 GDP binding(GO:0019003)
0.1 0.8 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.1 11.6 GO:0017048 Rho GTPase binding(GO:0017048)
0.1 0.9 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 3.3 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.1 84.2 GO:0005509 calcium ion binding(GO:0005509)
0.1 8.5 GO:0008013 beta-catenin binding(GO:0008013)
0.1 22.2 GO:0003924 GTPase activity(GO:0003924)
0.1 0.7 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.1 8.0 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.1 0.5 GO:0043208 glycosphingolipid binding(GO:0043208)
0.1 3.3 GO:0048487 beta-tubulin binding(GO:0048487)
0.1 1.9 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 2.2 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1 3.3 GO:0030507 spectrin binding(GO:0030507)
0.1 10.9 GO:0017137 Rab GTPase binding(GO:0017137)
0.1 17.5 GO:0015631 tubulin binding(GO:0015631)
0.1 2.0 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 4.0 GO:0035064 methylated histone binding(GO:0035064)
0.1 0.5 GO:0070569 uridylyltransferase activity(GO:0070569)
0.1 19.7 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.1 6.9 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.1 1.4 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 3.3 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 0.9 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.1 1.5 GO:0004890 GABA-A receptor activity(GO:0004890)
0.1 3.4 GO:0003774 motor activity(GO:0003774)
0.1 2.4 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 12.8 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 2.6 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 1.1 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 3.4 GO:0017124 SH3 domain binding(GO:0017124)
0.0 16.0 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 0.6 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.5 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 2.7 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.2 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.7 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 1.9 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 4.1 GO:0030246 carbohydrate binding(GO:0030246)
0.0 5.3 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.0 3.0 GO:0045296 cadherin binding(GO:0045296)
0.0 0.8 GO:0001076 transcription factor activity, RNA polymerase II transcription factor binding(GO:0001076)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 20.2 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.9 13.0 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.6 19.9 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.6 14.4 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.6 29.4 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.5 21.8 PID AURORA A PATHWAY Aurora A signaling
0.5 30.0 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.5 26.8 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.5 20.1 PID EPHB FWD PATHWAY EPHB forward signaling
0.4 15.3 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.3 8.4 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.3 4.4 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.3 10.9 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.3 2.1 PID IL5 PATHWAY IL5-mediated signaling events
0.3 14.1 PID HNF3A PATHWAY FOXA1 transcription factor network
0.3 8.8 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.3 18.1 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.3 9.1 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.3 4.1 ST G ALPHA S PATHWAY G alpha s Pathway
0.3 7.4 PID BCR 5PATHWAY BCR signaling pathway
0.3 7.9 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.2 5.9 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.2 39.5 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.2 5.5 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.2 9.0 PID CDC42 PATHWAY CDC42 signaling events
0.2 2.8 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.2 4.5 PID RHOA PATHWAY RhoA signaling pathway
0.1 2.7 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 3.3 PID INSULIN PATHWAY Insulin Pathway
0.1 2.5 PID BARD1 PATHWAY BARD1 signaling events
0.1 0.8 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.1 2.0 PID LKB1 PATHWAY LKB1 signaling events
0.0 2.0 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.0 0.9 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 3.4 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.0 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.1 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.4 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.5 PID RHOA REG PATHWAY Regulation of RhoA activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 11.9 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.7 13.0 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.7 15.0 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.7 12.4 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.6 8.8 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.6 5.5 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.6 11.7 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.5 13.5 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.5 18.2 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.5 20.3 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.5 11.0 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.4 10.8 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.4 7.2 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.4 10.3 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.4 15.3 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.4 8.0 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.4 30.3 REACTOME SIGNALING BY NOTCH1 Genes involved in Signaling by NOTCH1
0.4 6.3 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.4 7.9 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.4 8.8 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.4 9.5 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.3 12.7 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.3 11.3 REACTOME MYOGENESIS Genes involved in Myogenesis
0.3 4.8 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.3 8.0 REACTOME CA DEPENDENT EVENTS Genes involved in Ca-dependent events
0.3 19.8 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.3 6.3 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.3 6.5 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.3 4.1 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.3 6.0 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.3 3.1 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.2 7.0 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.2 2.8 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.2 2.0 REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.2 9.1 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.2 4.0 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.2 10.3 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.2 3.8 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.2 5.4 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.2 2.7 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.2 15.0 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.1 3.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 22.9 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.1 4.4 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.1 2.3 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 9.9 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 2.4 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1 2.1 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.1 6.6 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF
0.1 0.6 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.1 1.2 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 3.1 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 2.1 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.1 2.8 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.1 5.4 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.1 5.5 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.1 1.4 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.1 4.2 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.1 3.2 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.0 0.9 REACTOME SIGNALING BY NOTCH Genes involved in Signaling by NOTCH
0.0 1.0 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 3.6 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases