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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Snai1_Zeb1_Snai2

Z-value: 4.28

Motif logo

Transcription factors associated with Snai1_Zeb1_Snai2

Gene Symbol Gene ID Gene Info
ENSRNOG00000009594 snail family transcriptional repressor 1
ENSRNOG00000017863 zinc finger E-box binding homeobox 1
ENSRNOG00000047699 snail family transcriptional repressor 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Snai2rn6_v1_chr11_-_90406797_904067970.498.4e-21Click!
Snai1rn6_v1_chr3_+_164275095_1642750950.371.5e-11Click!
Zeb1rn6_v1_chr17_-_54678710_546787100.062.9e-01Click!

Activity profile of Snai1_Zeb1_Snai2 motif

Sorted Z-values of Snai1_Zeb1_Snai2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr10_+_56576428 280.46 ENSRNOT00000079237
ENSRNOT00000023291
claudin 7
chr8_-_22336794 196.70 ENSRNOT00000066340
adaptor-related protein complex 1, mu 2 subunit
chr2_-_30577218 190.07 ENSRNOT00000024674
occludin
chr9_-_104350308 173.06 ENSRNOT00000033958
solute carrier organic anion transporter family, member 4C1
chr7_+_94130852 159.57 ENSRNOT00000011485
mal, T-cell differentiation protein 2
chr11_-_67037115 155.62 ENSRNOT00000003137
immunoglobulin-like domain containing receptor 1
chr9_-_9985630 146.22 ENSRNOT00000071780
crumbs 3, cell polarity complex component
chr3_+_164822111 139.16 ENSRNOT00000014568
par-6 family cell polarity regulator beta
chr1_-_87221826 133.98 ENSRNOT00000046611
ENSRNOT00000028006
serine peptidase inhibitor, Kunitz type, 2
chr10_-_31359699 132.59 ENSRNOT00000081280
cytoplasmic FMR1 interacting protein 2
chr19_+_38768467 130.27 ENSRNOT00000027346
cadherin 1
chr3_+_119015412 121.41 ENSRNOT00000013605
solute carrier family 27 member 2
chr5_-_24631679 119.44 ENSRNOT00000010846
ENSRNOT00000067129
epithelial splicing regulatory protein 1
chr1_-_54748763 118.80 ENSRNOT00000074549
protein MAL2-like
chr2_-_30576591 116.35 ENSRNOT00000084667
occludin
chr3_-_52212412 112.14 ENSRNOT00000007615
polypeptide N-acetylgalactosaminyltransferase 3
chr6_-_96442682 108.09 ENSRNOT00000010923
transmembrane protein 30B
chr13_+_34610684 107.79 ENSRNOT00000093019
ENSRNOT00000003280
transcription factor CP2-like 1
chr12_-_21832813 106.43 ENSRNOT00000075280
claudin 3
chr2_-_187909394 106.10 ENSRNOT00000032355
RAB25, member RAS oncogene family
chr6_-_99843245 101.00 ENSRNOT00000080270
glutathione peroxidase 2
chr7_+_29435444 99.92 ENSRNOT00000008613
solute carrier family 5 member 8
chr5_-_159962218 97.85 ENSRNOT00000050729
chloride voltage-gated channel Kb
chr3_+_161018511 96.76 ENSRNOT00000019804
ENSRNOT00000039664
WAP four-disulfide core domain 2
chr4_+_157836912 95.30 ENSRNOT00000067271
sodium channel epithelial 1 alpha subunit
chr19_+_41710102 92.14 ENSRNOT00000021866
ENSRNOT00000079730
MARVEL domain containing 3
chr1_+_214328071 92.02 ENSRNOT00000024725
EPS8-like 2
chr5_+_133896141 91.45 ENSRNOT00000011434
PDZK1 interacting protein 1
chr3_+_111049118 90.91 ENSRNOT00000088870
serine peptidase inhibitor, Kunitz type 1
chr11_-_38274217 90.45 ENSRNOT00000002206
receptor-interacting serine-threonine kinase 4
chr6_-_11298216 89.59 ENSRNOT00000021135
epithelial cell adhesion molecule
chr13_+_111870121 88.57 ENSRNOT00000007333
interferon regulatory factor 6
chr2_+_188543137 87.72 ENSRNOT00000027850
mucin 1, cell surface associated
chr1_-_213907144 85.79 ENSRNOT00000054874
single Ig and TIR domain containing
chr3_+_111049315 85.58 ENSRNOT00000017223
serine peptidase inhibitor, Kunitz type 1
chr11_-_28527890 84.24 ENSRNOT00000002138
claudin 8
chr9_-_9985358 81.82 ENSRNOT00000080856
crumbs 3, cell polarity complex component
chr2_-_211322719 79.03 ENSRNOT00000027493
similar to KIAA1324 protein
chr10_+_86399827 78.23 ENSRNOT00000009299
growth factor receptor bound protein 7
chr5_+_137357674 77.88 ENSRNOT00000092813
similar to RIKEN cDNA 2610528J11
chr9_-_85445939 77.01 ENSRNOT00000072160
adaptor-related protein complex 1, sigma 3 subunit
chr10_-_20818128 73.55 ENSRNOT00000011061
WW and C2 domain containing 1
chr1_+_191704311 72.96 ENSRNOT00000024057
sodium channel epithelial 1 gamma subunit
chr18_+_70427007 71.88 ENSRNOT00000087959
ENSRNOT00000019512
myosin Vb
chr6_-_132608600 71.00 ENSRNOT00000015855
delta(4)-desaturase, sphingolipid 2
chr6_-_138250089 69.90 ENSRNOT00000048378
immunoglobulin heavy constant mu
chr14_+_16491573 69.89 ENSRNOT00000002995
sosondowah ankyrin repeat domain family member B
chr5_-_159962676 69.28 ENSRNOT00000013550
chloride voltage-gated channel Kb
chr1_+_64046377 69.25 ENSRNOT00000085010
transmembrane channel-like 4
chr6_-_50846965 69.00 ENSRNOT00000087300
solute carrier family 26 member 4
chr17_-_417480 68.85 ENSRNOT00000023685
fructose-bisphosphatase 1
chr13_-_70625842 68.15 ENSRNOT00000092499
laminin subunit gamma 2
chr3_-_81282157 68.11 ENSRNOT00000051258
LARGE xylosyl- and glucuronyltransferase 2
chr16_-_75637789 67.85 ENSRNOT00000058029
defensin beta 4
chrX_+_33443186 67.64 ENSRNOT00000005622
S100 calcium binding protein G
chr13_-_70626252 66.23 ENSRNOT00000036947
laminin subunit gamma 2
chr5_+_151741817 66.14 ENSRNOT00000081318
keratinocyte differentiation factor 1
chr3_-_48372583 65.17 ENSRNOT00000040482
ENSRNOT00000077788
ENSRNOT00000085426
dipeptidylpeptidase 4
chr10_-_31419235 64.79 ENSRNOT00000059496
cytoplasmic FMR1 interacting protein 2
chr8_+_117068582 63.98 ENSRNOT00000073559
aminomethyltransferase
chr12_+_2180150 63.87 ENSRNOT00000001322
syntaxin binding protein 2
chr10_+_13000090 63.69 ENSRNOT00000004845
claudin 6
chr20_+_4593389 63.23 ENSRNOT00000001174
solute carrier family 44, member 4
chr7_+_76059386 61.83 ENSRNOT00000009337
grainyhead-like transcription factor 2
chr10_+_91254058 59.76 ENSRNOT00000087218
ENSRNOT00000065373
formin-like 1
chr13_-_48848864 58.81 ENSRNOT00000077857
ENSRNOT00000068003
major facilitator superfamily domain containing 4
chr1_+_221673590 58.14 ENSRNOT00000038016
CDC42 binding protein kinase gamma
chr10_+_47961056 57.89 ENSRNOT00000027312
family with sequence similarity 83, member G
chr20_+_48335540 57.47 ENSRNOT00000000352
CD24 molecule
chr6_-_55001464 57.19 ENSRNOT00000006618
aryl hydrocarbon receptor
chr7_-_143603803 57.10 ENSRNOT00000038480
keratin 8
chr17_+_15814132 55.42 ENSRNOT00000032997
sushi domain containing 3
chr10_+_71159869 54.85 ENSRNOT00000075977
ENSRNOT00000047427
HNF1 homeobox B
chr14_-_18839420 54.76 ENSRNOT00000034090
chemokine (C-X-C motif) ligand 3
chr8_+_54925607 54.11 ENSRNOT00000059210
placenta expressed transcript 1
chr7_-_117070936 53.58 ENSRNOT00000048446
family with sequence similarity 83, member H
chr10_+_10644572 53.28 ENSRNOT00000004026
periplakin
chr17_-_8607494 53.06 ENSRNOT00000016138
solute carrier family 25, member 48
chr3_-_138462063 52.25 ENSRNOT00000065553
ovo-like zinc finger 2
chr14_-_60276794 52.04 ENSRNOT00000048509
solute carrier family 34 member 2
chr5_-_171648327 52.04 ENSRNOT00000082847
Rho guanine nucleotide exchange factor 16
chr9_+_81689802 51.37 ENSRNOT00000021432
villin 1
chr3_-_6626284 51.27 ENSRNOT00000012494
ficolin B
chr7_+_130296897 50.72 ENSRNOT00000044854
adrenomedullin 2
chrX_+_71272042 50.46 ENSRNOT00000076034
ENSRNOT00000076816
gap junction protein, beta 1
chr11_+_71211768 49.76 ENSRNOT00000079753
uncharacterized LOC100910650
chr2_+_209097927 49.29 ENSRNOT00000023807
DENN domain containing 2D
chr2_-_192671059 49.26 ENSRNOT00000012174
small proline-rich protein 1A
chr7_-_139394166 49.21 ENSRNOT00000082429
vitamin D (1,25- dihydroxyvitamin D3) receptor
chr7_+_143060597 49.19 ENSRNOT00000087481
keratin 7
chr15_-_37383277 49.00 ENSRNOT00000011711
gap junction protein, beta 2
chr6_+_33885495 48.98 ENSRNOT00000086633
syndecan 1
chr2_-_238468435 48.59 ENSRNOT00000055537
rho guanine nucleotide exchange factor 38-like
chr4_+_84478839 48.49 ENSRNOT00000012668
proline rich 15
chr1_-_189199376 48.34 ENSRNOT00000021027
uromodulin
chr11_-_70499200 47.20 ENSRNOT00000002439
solute carrier family 12, member 8
chr10_+_14122878 47.06 ENSRNOT00000052008
heparan sulfate-glucosamine 3-sulfotransferase 6
chr11_+_50781127 47.04 ENSRNOT00000002738
activated leukocyte cell adhesion molecule
chr10_-_82887497 46.48 ENSRNOT00000005644
integrin subunit alpha 3
chr6_+_99356509 46.13 ENSRNOT00000008416
A-kinase anchoring protein 5
chr7_-_107634287 46.07 ENSRNOT00000093672
ENSRNOT00000087116
src-like adaptor
chr5_-_79008363 45.17 ENSRNOT00000010040
kinesin family member 12
chr3_-_93216495 44.97 ENSRNOT00000010580
ets homologous factor
chr5_-_171648563 44.82 ENSRNOT00000072786
Rho guanine nucleotide exchange factor 16
chr7_-_12707922 44.78 ENSRNOT00000013857
mitotic spindle positioning
chr3_-_44342355 44.71 ENSRNOT00000059280
activin A receptor type 1C
chr4_-_85386231 44.54 ENSRNOT00000015316
indolethylamine N-methyltransferase
chr11_-_38088753 44.39 ENSRNOT00000002713
transmembrane protease, serine 2
chr17_+_32904119 44.38 ENSRNOT00000059854
serpin family B member 1A
chr7_-_101140308 44.01 ENSRNOT00000006279
family with sequence similarity 84, member B
chr10_+_109904259 43.26 ENSRNOT00000073886
ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
chr12_+_16912249 43.14 ENSRNOT00000085936
transmembrane protein 184A
chr6_-_138508753 43.13 ENSRNOT00000006888
immunoglobulin heavy constant mu
chr4_-_68597586 42.73 ENSRNOT00000015921
similar to RIKEN cDNA E330009J07 gene
chr6_+_27975417 42.25 ENSRNOT00000077830
dystrobrevin, beta
chr13_+_52645257 42.20 ENSRNOT00000012801
ladinin 1
chr1_+_32199810 42.02 ENSRNOT00000036714
solute carrier family 6 member 19
chr9_-_14706557 42.00 ENSRNOT00000048975
triggering receptor expressed on myeloid cells-like 4
chr1_-_89399039 41.62 ENSRNOT00000028585
ENSRNOT00000044678
lipolysis stimulated lipoprotein receptor
chr10_-_88060561 41.53 ENSRNOT00000019133
keratin 19
chr5_-_158439078 41.24 ENSRNOT00000025517
kelch domain containing 7A
chr7_-_51353068 41.09 ENSRNOT00000008222
pro-apoptotic WT1 regulator
chr6_-_39363367 41.05 ENSRNOT00000088687
ENSRNOT00000065531
family with sequence similarity 84, member A
chr6_-_26486695 40.84 ENSRNOT00000073236
keratinocyte associated protein 3
chrX_+_120624518 40.53 ENSRNOT00000007967
solute carrier family 6 member 14
chr5_-_79874671 40.42 ENSRNOT00000084563
tenascin C
chr9_+_4107246 40.35 ENSRNOT00000078212

chr8_-_76579099 40.34 ENSRNOT00000088628
family with sequence similarity 81, member A
chr1_+_277689729 40.04 ENSRNOT00000051834
von Willebrand factor A domain containing 2
chr9_-_100306194 40.00 ENSRNOT00000087584
similar to hypothetical protein FLJ22671
chr1_-_227441442 39.99 ENSRNOT00000028433
membrane spanning 4-domains A1
chr2_+_251983339 39.67 ENSRNOT00000020230
mucolipin 3
chr19_-_11341863 39.64 ENSRNOT00000025694
metallothionein 4
chr20_+_9743269 39.29 ENSRNOT00000001533
ENSRNOT00000083505
ATP binding cassette subfamily G member 1
chr13_+_52553775 38.74 ENSRNOT00000011991
cysteine and glycine-rich protein 1
chr1_+_64114721 38.66 ENSRNOT00000080466
transmembrane channel-like 4
chr5_-_126080698 38.59 ENSRNOT00000008739
barttin CLCNK type accessory beta subunit
chr10_-_105116916 38.53 ENSRNOT00000012373
envoplakin
chr16_-_37495758 38.43 ENSRNOT00000014229
hydroxyprostaglandin dehydrogenase 15 (NAD)
chr1_+_83933942 38.41 ENSRNOT00000068690
cytochrome P450, family 2, subfamily f, polypeptide 4
chr7_-_3010350 38.37 ENSRNOT00000006796
erb-b2 receptor tyrosine kinase 3
chr20_+_9586075 38.35 ENSRNOT00000001527
ENSRNOT00000079509
glucagon-like peptide 1 receptor
chr15_-_42947656 38.35 ENSRNOT00000030007
protein tyrosine kinase 2 beta
chr10_-_65424802 38.33 ENSRNOT00000018468
Tnf receptor associated factor 4
chr14_-_35149608 38.19 ENSRNOT00000003050
ENSRNOT00000090654
KIT proto-oncogene receptor tyrosine kinase
chr7_+_99158119 38.16 ENSRNOT00000044127
cytochrome P450 2B1
chr10_-_19164505 38.14 ENSRNOT00000009058
forkhead box I1
chr4_+_65801505 37.83 ENSRNOT00000018331
transmembrane protein 213
chr5_-_172769421 37.77 ENSRNOT00000021285
protein kinase C, zeta
chr2_-_211207465 37.62 ENSRNOT00000027263
cadherin, EGF LAG seven-pass G-type receptor 2
chr4_+_98457810 37.44 ENSRNOT00000074175

chr5_+_29538380 37.40 ENSRNOT00000010845
calbindin 1
chr11_-_38103290 37.33 ENSRNOT00000066413
transmembrane protease, serine 2
chr5_-_75005567 36.95 ENSRNOT00000016068
hypothetical protein LOC685849
chr6_+_27975849 36.78 ENSRNOT00000060810
dystrobrevin, beta
chr1_-_280233929 36.72 ENSRNOT00000085778
shootin 1
chrX_+_70596901 36.63 ENSRNOT00000088114
discs large MAGUK scaffold protein 3
chr1_+_242959488 36.59 ENSRNOT00000015668
dedicator of cytokinesis 8
chr9_-_82336806 36.27 ENSRNOT00000024667
solute carrier family 23, member 3
chr1_-_198128857 36.19 ENSRNOT00000026496
coronin 1A
chr1_-_22206505 36.12 ENSRNOT00000061234
monooxygenase, DBH-like 1
chr13_+_89755845 36.10 ENSRNOT00000005550
nectin cell adhesion molecule 4
chr7_-_143317674 35.94 ENSRNOT00000080010
keratin 5
chr4_+_106323089 35.83 ENSRNOT00000091402

chr14_-_82975263 35.77 ENSRNOT00000024165
solute carrier family 5 member 1
chr16_+_6078122 35.72 ENSRNOT00000021407
choline dehydrogenase
chr8_+_91070073 35.61 ENSRNOT00000012904
SH3 domain binding glutamate-rich protein like 2
chr14_-_80973456 35.60 ENSRNOT00000013257
HGF activator
chr10_-_90410569 35.16 ENSRNOT00000036112
integrin subunit alpha 2b
chr7_+_143629455 35.07 ENSRNOT00000073951
keratin 18
chrX_+_29430831 35.02 ENSRNOT00000068337
ENSRNOT00000087621
EGF-like-domain, multiple 6
chr5_+_149077412 34.97 ENSRNOT00000014666
matrilin 1, cartilage matrix protein
chr10_+_10555337 34.88 ENSRNOT00000032495
similar to MGC45438 protein
chr3_+_79918969 34.71 ENSRNOT00000016306
Spi-1 proto-oncogene
chr16_-_18757918 34.65 ENSRNOT00000084172
surfactant protein D
chr1_+_235166718 34.47 ENSRNOT00000020201
G protein subunit alpha 14
chr2_-_195935878 34.42 ENSRNOT00000028440
cingulin
chr5_-_159946446 34.19 ENSRNOT00000089184
chloride voltage-gated channel Ka
chr11_-_37993204 34.10 ENSRNOT00000077050
ENSRNOT00000091614
ENSRNOT00000002683
family with sequence similarity 3, member B
chr7_+_99142450 33.98 ENSRNOT00000079036
ENSRNOT00000091923
cytochrome P450 2B1
chr20_-_22004209 33.97 ENSRNOT00000086250
ENSRNOT00000068778
rhotekin 2
chr10_+_103713045 33.83 ENSRNOT00000004351
SLC9A3 regulator 1
chr17_-_84488480 33.45 ENSRNOT00000000158
ENSRNOT00000075983
nebulette
chr9_-_19476646 33.25 ENSRNOT00000013703
ectonucleotide pyrophosphatase/phosphodiesterase 5
chr5_+_137257637 33.21 ENSRNOT00000093001
ELOVL fatty acid elongase 1
chr8_-_32280869 33.16 ENSRNOT00000009139
suppression of tumorigenicity 14
chr3_+_16413080 33.14 ENSRNOT00000040386
Ig kappa chain V19-17-like
chr19_+_784618 33.13 ENSRNOT00000014749
CKLF-like MARVEL transmembrane domain containing 4
chr7_+_114724610 33.08 ENSRNOT00000014541
DENN domain containing 3
chr10_-_65692016 32.99 ENSRNOT00000085074
ENSRNOT00000038690
solute carrier family 13 member 2
chr8_-_119012671 32.94 ENSRNOT00000028435
parathyroid hormone 1 receptor
chr2_-_80408672 32.79 ENSRNOT00000067638
family with sequence similarity 105, member A
chr4_+_102489916 32.72 ENSRNOT00000082031

chr4_-_56114254 32.63 ENSRNOT00000010673
leucine rich repeat containing 4
chr8_+_57886168 32.53 ENSRNOT00000039336
exophilin 5
chr11_+_61662270 32.52 ENSRNOT00000079521
zinc finger, DHHC-type containing 23
chr4_+_116968000 32.47 ENSRNOT00000020786
empty spiracles homeobox 1
chr16_-_18766174 32.45 ENSRNOT00000084813
surfactant protein D
chr1_+_201429771 32.42 ENSRNOT00000027836
pleckstrin homology domain containing A1
chr1_+_91363492 32.34 ENSRNOT00000014517
CCAAT/enhancer binding protein alpha

Network of associatons between targets according to the STRING database.

First level regulatory network of Snai1_Zeb1_Snai2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
57.2 229.0 GO:0060671 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
43.3 129.9 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
34.7 312.7 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
34.5 137.9 GO:0060066 oviduct development(GO:0060066)
33.9 101.6 GO:0009609 response to symbiotic bacterium(GO:0009609)
32.2 418.6 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
30.4 304.3 GO:0070673 response to interleukin-18(GO:0070673)
29.2 87.6 GO:0006667 sphinganine metabolic process(GO:0006667)
28.6 85.8 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
25.7 128.6 GO:0050828 regulation of liquid surface tension(GO:0050828)
23.7 189.7 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
23.3 69.9 GO:0061296 mesonephros morphogenesis(GO:0061206) mesonephric nephron development(GO:0061215) mesonephric nephron morphogenesis(GO:0061228) mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis(GO:0061235) regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061295) negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061296) mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:1901146)
23.1 69.2 GO:0061744 motor behavior(GO:0061744)
22.6 113.2 GO:0060327 cytoplasmic actin-based contraction involved in cell motility(GO:0060327)
22.4 112.1 GO:0018242 protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
22.0 88.0 GO:0072139 glomerular parietal epithelial cell differentiation(GO:0072139) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
21.6 86.6 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
21.5 64.4 GO:0042939 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
21.2 169.3 GO:0030321 transepithelial chloride transport(GO:0030321)
21.1 21.1 GO:1904673 regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis(GO:0072039) negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis(GO:0072040) mesenchymal cell apoptotic process involved in nephron morphogenesis(GO:1901145) negative regulation of somatic stem cell population maintenance(GO:1904673)
19.5 38.9 GO:0099545 trans-synaptic signaling by trans-synaptic complex(GO:0099545)
19.4 38.9 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
18.8 131.9 GO:0072025 distal convoluted tubule development(GO:0072025) metanephric distal convoluted tubule development(GO:0072221)
18.3 54.9 GO:0072714 response to selenite ion(GO:0072714)
17.2 68.8 GO:0046351 disaccharide biosynthetic process(GO:0046351)
17.2 68.7 GO:0036394 amylase secretion(GO:0036394)
17.0 51.1 GO:0072053 renal inner medulla development(GO:0072053)
16.8 50.5 GO:1905218 cellular response to astaxanthin(GO:1905218)
16.7 217.3 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
16.0 64.0 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
15.7 94.2 GO:0032439 endosome localization(GO:0032439)
15.7 47.0 GO:0042197 chlorinated hydrocarbon metabolic process(GO:0042196) halogenated hydrocarbon metabolic process(GO:0042197)
15.6 62.4 GO:0038183 bile acid signaling pathway(GO:0038183)
15.5 62.0 GO:0040009 regulation of growth rate(GO:0040009)
15.2 60.8 GO:2000664 positive regulation of interleukin-5 secretion(GO:2000664)
14.9 44.7 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
14.7 58.6 GO:0060214 endocardium formation(GO:0060214)
14.5 43.5 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
14.4 57.6 GO:0018992 germ-line sex determination(GO:0018992)
14.2 42.7 GO:2000611 basement membrane disassembly(GO:0034769) positive regulation of thyroid hormone generation(GO:2000611)
13.9 83.4 GO:0035331 negative regulation of hippo signaling(GO:0035331)
13.7 41.1 GO:1903238 positive regulation of leukocyte tethering or rolling(GO:1903238)
13.7 54.7 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
13.6 95.5 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
13.5 40.6 GO:0042125 protein glycosylation at cell surface(GO:0033575) protein galactosylation at cell surface(GO:0033580) protein galactosylation(GO:0042125)
13.5 54.0 GO:0000050 urea cycle(GO:0000050)
13.3 40.0 GO:0007161 calcium-independent cell-matrix adhesion(GO:0007161)
13.2 66.1 GO:0000066 mitochondrial ornithine transport(GO:0000066)
13.1 65.7 GO:0061218 negative regulation of mesonephros development(GO:0061218) negative regulation of branching involved in ureteric bud morphogenesis(GO:0090191)
12.9 38.8 GO:0071529 cementum mineralization(GO:0071529)
12.9 38.6 GO:0042412 taurine biosynthetic process(GO:0042412)
12.9 51.5 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
12.8 38.4 GO:0060974 cell migration involved in heart formation(GO:0060974)
12.8 38.3 GO:2000537 regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
12.8 76.5 GO:0010481 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
12.7 38.2 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
12.6 63.2 GO:0008292 acetylcholine biosynthetic process(GO:0008292) acetate ester biosynthetic process(GO:1900620)
12.5 112.1 GO:1902414 protein localization to cell junction(GO:1902414)
12.0 36.1 GO:0046333 octopamine biosynthetic process(GO:0006589) octopamine metabolic process(GO:0046333)
11.8 47.1 GO:0072679 thymocyte migration(GO:0072679)
11.7 23.4 GO:0070602 regulation of centromeric sister chromatid cohesion(GO:0070602)
11.5 34.6 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
11.4 34.3 GO:0032759 TRAIL production(GO:0032639) regulation of TRAIL production(GO:0032679) positive regulation of TRAIL production(GO:0032759)
11.4 34.1 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
11.3 11.3 GO:0070650 actin filament bundle distribution(GO:0070650)
11.2 33.7 GO:0070904 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
11.2 145.4 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
11.2 44.7 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
11.2 44.6 GO:0033277 abortive mitotic cell cycle(GO:0033277)
11.1 33.3 GO:0007056 spindle assembly involved in female meiosis(GO:0007056)
11.1 33.2 GO:0010133 proline catabolic process to glutamate(GO:0010133)
10.9 21.7 GO:0002572 pro-T cell differentiation(GO:0002572)
10.8 32.5 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
10.8 32.4 GO:0015680 intracellular copper ion transport(GO:0015680)
10.7 96.7 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
10.6 42.3 GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
10.5 52.6 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
10.4 124.5 GO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902166)
10.3 30.8 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
10.0 30.1 GO:1900368 regulation of RNA interference(GO:1900368)
9.9 29.7 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
9.9 118.3 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
9.8 39.3 GO:0034436 glycoprotein transport(GO:0034436)
9.6 28.9 GO:0071461 cellular response to redox state(GO:0071461)
9.6 28.8 GO:0060369 positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
9.6 57.4 GO:0032762 mast cell cytokine production(GO:0032762)
9.5 19.0 GO:0060300 regulation of cytokine activity(GO:0060300)
9.4 18.9 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
9.4 113.2 GO:0051014 actin filament severing(GO:0051014)
9.4 18.8 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
9.2 18.5 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
9.2 36.8 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
9.2 36.7 GO:0006565 L-serine catabolic process(GO:0006565)
9.1 9.1 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
9.1 27.3 GO:0001698 gastrin-induced gastric acid secretion(GO:0001698)
9.1 27.2 GO:1903596 regulation of gap junction assembly(GO:1903596)
9.1 54.3 GO:0035963 cellular response to interleukin-13(GO:0035963)
8.9 35.8 GO:0001951 intestinal D-glucose absorption(GO:0001951)
8.8 44.2 GO:0090168 Golgi reassembly(GO:0090168)
8.8 8.8 GO:2000662 interleukin-5 secretion(GO:0072603) regulation of interleukin-5 secretion(GO:2000662)
8.8 26.3 GO:1901740 negative regulation of myoblast fusion(GO:1901740)
8.8 17.5 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
8.8 70.1 GO:0015705 iodide transport(GO:0015705)
8.7 26.0 GO:0015864 pyrimidine nucleoside transport(GO:0015864)
8.6 60.3 GO:0070782 phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
8.6 51.5 GO:0002457 T cell antigen processing and presentation(GO:0002457)
8.4 92.3 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
8.3 100.2 GO:0007028 cytoplasm organization(GO:0007028)
8.3 16.6 GO:0008592 regulation of Toll signaling pathway(GO:0008592) negative regulation of Toll signaling pathway(GO:0045751)
8.3 24.8 GO:0042938 dipeptide transport(GO:0042938)
8.2 123.4 GO:0097284 hepatocyte apoptotic process(GO:0097284)
8.2 8.2 GO:0006212 uracil catabolic process(GO:0006212)
8.2 16.4 GO:2000830 vacuolar phosphate transport(GO:0007037) positive regulation of parathyroid hormone secretion(GO:2000830)
8.2 32.8 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
8.1 32.4 GO:0021564 vagus nerve development(GO:0021564)
8.1 24.2 GO:0019740 regulation of nitrogen utilization(GO:0006808) nitrogen utilization(GO:0019740) negative regulation of retinal cell programmed cell death(GO:0046671)
8.0 8.0 GO:0043366 beta selection(GO:0043366)
8.0 119.6 GO:0035313 wound healing, spreading of epidermal cells(GO:0035313)
7.9 7.9 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
7.6 7.6 GO:0021769 orbitofrontal cortex development(GO:0021769)
7.6 68.4 GO:0060056 mammary gland involution(GO:0060056)
7.6 22.8 GO:0032789 saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
7.6 22.8 GO:0032532 regulation of microvillus length(GO:0032532)
7.6 37.8 GO:0070633 transepithelial transport(GO:0070633)
7.5 29.8 GO:0097069 cellular response to thyroxine stimulus(GO:0097069)
7.4 134.0 GO:0001771 immunological synapse formation(GO:0001771)
7.4 7.4 GO:0070947 neutrophil mediated killing of fungus(GO:0070947)
7.3 22.0 GO:0071934 thiamine transmembrane transport(GO:0071934)
7.3 7.3 GO:0051121 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
7.3 36.5 GO:0010533 regulation of activation of Janus kinase activity(GO:0010533)
7.3 51.1 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
7.3 43.7 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
7.3 29.1 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
7.3 36.3 GO:0045218 zonula adherens maintenance(GO:0045218)
7.2 43.3 GO:0097070 ductus arteriosus closure(GO:0097070)
7.2 35.8 GO:0038027 apolipoprotein A-I-mediated signaling pathway(GO:0038027)
7.1 14.3 GO:0071586 CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
7.1 21.3 GO:0071163 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) DNA replication preinitiation complex assembly(GO:0071163) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
7.1 177.4 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
7.1 7.1 GO:0007529 establishment of synaptic specificity at neuromuscular junction(GO:0007529)
7.0 28.1 GO:1903999 negative regulation of eating behavior(GO:1903999)
7.0 21.0 GO:0016267 O-glycan processing, core 1(GO:0016267)
7.0 48.9 GO:0045341 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343) positive regulation of MHC class I biosynthetic process(GO:0045345)
6.9 27.5 GO:0002386 immune response in mucosal-associated lymphoid tissue(GO:0002386)
6.7 33.7 GO:0046104 thymidine metabolic process(GO:0046104)
6.7 13.4 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
6.6 39.9 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
6.6 19.9 GO:1902226 regulation of macrophage colony-stimulating factor signaling pathway(GO:1902226) regulation of response to macrophage colony-stimulating factor(GO:1903969) regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903972)
6.6 13.2 GO:0070103 regulation of interleukin-6-mediated signaling pathway(GO:0070103)
6.6 19.8 GO:0002238 response to molecule of fungal origin(GO:0002238)
6.6 6.6 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
6.6 19.8 GO:0060157 urinary bladder development(GO:0060157)
6.6 19.7 GO:2000182 regulation of progesterone biosynthetic process(GO:2000182)
6.6 13.1 GO:0002901 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
6.5 32.7 GO:0002934 desmosome organization(GO:0002934)
6.5 26.1 GO:0090118 receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118)
6.5 32.5 GO:1900020 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
6.4 76.9 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
6.4 102.1 GO:0031268 pseudopodium organization(GO:0031268)
6.4 44.6 GO:0046710 GDP metabolic process(GO:0046710)
6.4 25.4 GO:0002343 peripheral B cell selection(GO:0002343) B cell affinity maturation(GO:0002344)
6.2 12.4 GO:1904387 cellular response to L-phenylalanine derivative(GO:1904387)
6.2 24.7 GO:0042126 nitrate metabolic process(GO:0042126)
6.2 30.8 GO:0010037 response to carbon dioxide(GO:0010037)
6.1 18.4 GO:0042822 pyridoxal phosphate metabolic process(GO:0042822)
6.1 24.5 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
6.1 12.2 GO:2000721 positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
6.1 6.1 GO:0006701 progesterone biosynthetic process(GO:0006701)
6.1 30.4 GO:0003433 chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
6.1 18.2 GO:0051977 lysophospholipid transport(GO:0051977)
6.1 18.2 GO:2000853 negative regulation of corticosterone secretion(GO:2000853)
6.0 18.1 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
6.0 66.4 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
6.0 78.5 GO:0034063 stress granule assembly(GO:0034063)
6.0 18.0 GO:0070384 Harderian gland development(GO:0070384)
6.0 17.9 GO:0071422 succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422)
5.9 5.9 GO:0060160 negative regulation of dopamine receptor signaling pathway(GO:0060160)
5.9 17.8 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
5.9 17.8 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
5.9 23.7 GO:0009992 cellular water homeostasis(GO:0009992)
5.9 11.8 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
5.9 76.4 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
5.9 17.6 GO:1904580 regulation of intracellular mRNA localization(GO:1904580)
5.8 23.3 GO:0051958 methotrexate transport(GO:0051958)
5.8 28.9 GO:0050917 sensory perception of umami taste(GO:0050917)
5.8 11.5 GO:0021782 glial cell development(GO:0021782)
5.8 11.5 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
5.7 28.7 GO:2000504 positive regulation of blood vessel remodeling(GO:2000504)
5.7 28.6 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
5.7 17.2 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
5.7 5.7 GO:2000338 chemokine (C-X-C motif) ligand 1 production(GO:0072566) regulation of chemokine (C-X-C motif) ligand 1 production(GO:2000338)
5.7 22.9 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
5.7 11.4 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
5.7 34.1 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
5.6 78.9 GO:0043312 neutrophil degranulation(GO:0043312)
5.6 56.3 GO:0006968 cellular defense response(GO:0006968)
5.6 16.8 GO:0086097 regulation of renal output by angiotensin(GO:0002019) phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
5.6 11.1 GO:1904685 positive regulation of metalloendopeptidase activity(GO:1904685)
5.6 99.9 GO:1900027 regulation of ruffle assembly(GO:1900027)
5.5 16.6 GO:1902287 trigeminal nerve morphogenesis(GO:0021636) trigeminal nerve structural organization(GO:0021637) trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
5.5 16.5 GO:0042350 GDP-L-fucose biosynthetic process(GO:0042350)
5.5 16.4 GO:0032380 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
5.4 21.8 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
5.4 108.7 GO:0070831 basement membrane assembly(GO:0070831)
5.4 10.8 GO:0015746 citrate transport(GO:0015746)
5.4 32.4 GO:0051136 regulation of NK T cell differentiation(GO:0051136)
5.3 5.3 GO:0035622 intrahepatic bile duct development(GO:0035622)
5.3 37.3 GO:0050915 sensory perception of sour taste(GO:0050915)
5.3 31.9 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
5.3 5.3 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
5.3 47.4 GO:0045656 negative regulation of monocyte differentiation(GO:0045656)
5.3 21.1 GO:0014028 notochord formation(GO:0014028)
5.3 68.4 GO:0038094 Fc-gamma receptor signaling pathway(GO:0038094)
5.2 10.5 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
5.2 36.7 GO:0060600 dichotomous subdivision of an epithelial terminal unit(GO:0060600)
5.2 20.6 GO:0046655 folic acid metabolic process(GO:0046655)
5.1 20.6 GO:0045404 positive regulation of interleukin-4 biosynthetic process(GO:0045404)
5.1 5.1 GO:0042531 regulation of tyrosine phosphorylation of STAT protein(GO:0042509) positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
5.1 15.4 GO:0071640 regulation of macrophage inflammatory protein 1 alpha production(GO:0071640)
5.1 40.6 GO:0042421 norepinephrine biosynthetic process(GO:0042421)
5.0 10.1 GO:2000562 negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
5.0 20.1 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
5.0 9.9 GO:2000587 negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
5.0 9.9 GO:0022614 membrane to membrane docking(GO:0022614)
5.0 14.9 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
4.9 4.9 GO:0070946 neutrophil mediated killing of gram-positive bacterium(GO:0070946)
4.9 4.9 GO:0002634 regulation of germinal center formation(GO:0002634)
4.9 34.4 GO:0007182 common-partner SMAD protein phosphorylation(GO:0007182)
4.9 14.6 GO:1903165 response to polycyclic arene(GO:1903165)
4.8 14.4 GO:0060545 positive regulation of necroptotic process(GO:0060545)
4.8 9.5 GO:1900222 negative regulation of beta-amyloid clearance(GO:1900222)
4.8 14.3 GO:0071579 regulation of zinc ion transport(GO:0071579)
4.7 14.2 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
4.7 14.2 GO:0046416 D-amino acid metabolic process(GO:0046416)
4.7 4.7 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
4.7 42.3 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
4.7 14.1 GO:1903173 phytol metabolic process(GO:0033306) fatty alcohol metabolic process(GO:1903173)
4.7 18.7 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
4.7 70.2 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
4.7 14.0 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
4.7 9.3 GO:0042360 vitamin E metabolic process(GO:0042360)
4.6 9.3 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
4.6 9.3 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
4.6 9.3 GO:0002476 antigen processing and presentation of endogenous peptide antigen via MHC class Ib(GO:0002476)
4.6 13.9 GO:0006713 glucocorticoid catabolic process(GO:0006713)
4.6 9.2 GO:0042159 lipoprotein catabolic process(GO:0042159)
4.6 69.2 GO:0035269 protein O-linked mannosylation(GO:0035269)
4.6 9.2 GO:0060155 platelet dense granule organization(GO:0060155)
4.6 13.8 GO:1900060 negative regulation of ceramide biosynthetic process(GO:1900060)
4.6 13.7 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
4.6 18.2 GO:0016103 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
4.6 13.7 GO:1904721 negative regulation of mRNA cleavage(GO:0031438) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
4.5 77.2 GO:0031424 keratinization(GO:0031424)
4.5 18.1 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
4.5 22.6 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
4.5 58.7 GO:0060856 establishment of blood-brain barrier(GO:0060856)
4.5 13.5 GO:0042636 negative regulation of hair cycle(GO:0042636)
4.5 4.5 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
4.5 44.5 GO:0070244 negative regulation of thymocyte apoptotic process(GO:0070244)
4.4 13.3 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
4.4 30.9 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
4.3 8.7 GO:0071072 negative regulation of phospholipid biosynthetic process(GO:0071072)
4.3 13.0 GO:0046061 dATP catabolic process(GO:0046061)
4.3 13.0 GO:0044209 AMP salvage(GO:0044209)
4.3 12.9 GO:2000670 positive regulation of dendritic cell apoptotic process(GO:2000670)
4.3 12.9 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
4.3 8.6 GO:2000566 positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566)
4.3 17.2 GO:0046878 positive regulation of saliva secretion(GO:0046878)
4.2 25.4 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
4.2 29.6 GO:0060075 regulation of resting membrane potential(GO:0060075)
4.2 42.2 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
4.2 46.4 GO:1900165 negative regulation of interleukin-6 secretion(GO:1900165)
4.2 37.8 GO:2000035 regulation of stem cell division(GO:2000035)
4.2 12.6 GO:0035483 gastric emptying(GO:0035483)
4.2 54.5 GO:0032836 glomerular basement membrane development(GO:0032836)
4.2 4.2 GO:1904100 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
4.2 12.5 GO:0044375 regulation of peroxisome size(GO:0044375)
4.2 12.5 GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
4.2 96.0 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
4.2 4.2 GO:1904170 regulation of bleb assembly(GO:1904170)
4.2 91.7 GO:0060644 mammary gland epithelial cell differentiation(GO:0060644)
4.2 37.4 GO:0046146 tetrahydrobiopterin metabolic process(GO:0046146)
4.1 37.2 GO:0045217 cell-cell junction maintenance(GO:0045217)
4.1 12.3 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
4.1 44.8 GO:0033630 positive regulation of cell adhesion mediated by integrin(GO:0033630)
4.0 36.4 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
4.0 12.1 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
4.0 16.1 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
4.0 8.1 GO:0007223 Wnt signaling pathway, calcium modulating pathway(GO:0007223)
4.0 12.1 GO:0030824 negative regulation of cGMP metabolic process(GO:0030824)
4.0 12.1 GO:0032978 protein insertion into membrane from inner side(GO:0032978)
4.0 8.0 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
4.0 4.0 GO:0045626 negative regulation of T-helper 1 cell differentiation(GO:0045626)
4.0 12.0 GO:0035624 receptor transactivation(GO:0035624) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625)
4.0 8.0 GO:0032847 regulation of cellular pH reduction(GO:0032847) positive regulation of cellular pH reduction(GO:0032849)
4.0 12.0 GO:0006742 NADP catabolic process(GO:0006742)
4.0 4.0 GO:0019860 uracil metabolic process(GO:0019860)
4.0 8.0 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
4.0 11.9 GO:1901377 toxin catabolic process(GO:0009407) mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) secondary metabolite catabolic process(GO:0090487) organic heteropentacyclic compound catabolic process(GO:1901377)
3.9 27.4 GO:0002315 marginal zone B cell differentiation(GO:0002315)
3.9 31.3 GO:0006578 amino-acid betaine biosynthetic process(GO:0006578)
3.9 11.7 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
3.9 54.6 GO:0010759 positive regulation of macrophage chemotaxis(GO:0010759)
3.9 11.7 GO:0018094 protein polyglycylation(GO:0018094)
3.8 11.5 GO:0016129 phytosteroid metabolic process(GO:0016128) phytosteroid biosynthetic process(GO:0016129)
3.8 38.4 GO:0006670 sphingosine metabolic process(GO:0006670)
3.8 11.5 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
3.8 22.9 GO:0010990 regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991)
3.8 15.2 GO:0070839 divalent metal ion export(GO:0070839)
3.8 7.6 GO:0097187 dentinogenesis(GO:0097187)
3.8 19.0 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
3.8 3.8 GO:0043316 cytotoxic T cell degranulation(GO:0043316)
3.8 7.5 GO:0002586 regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002580) regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002586)
3.8 22.5 GO:0060481 lobar bronchus epithelium development(GO:0060481)
3.8 11.3 GO:1902959 regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902959) positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963) regulation of aspartic-type peptidase activity(GO:1905245) positive regulation of aspartic-type peptidase activity(GO:1905247)
3.7 11.2 GO:0071395 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
3.7 7.5 GO:0035771 interleukin-4-mediated signaling pathway(GO:0035771)
3.7 18.6 GO:0032020 ISG15-protein conjugation(GO:0032020)
3.7 3.7 GO:1902164 positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
3.7 3.7 GO:0032423 regulation of mismatch repair(GO:0032423)
3.7 14.8 GO:2000389 regulation of neutrophil extravasation(GO:2000389)
3.7 18.4 GO:0045110 intermediate filament bundle assembly(GO:0045110)
3.7 25.8 GO:0000103 sulfate assimilation(GO:0000103)
3.7 11.1 GO:0061073 ciliary body morphogenesis(GO:0061073)
3.7 14.7 GO:0031642 negative regulation of myelination(GO:0031642)
3.6 7.2 GO:0051695 actin filament uncapping(GO:0051695)
3.6 7.2 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
3.6 46.6 GO:0021796 cerebral cortex regionalization(GO:0021796)
3.6 7.2 GO:0031652 positive regulation of heat generation(GO:0031652)
3.6 17.8 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
3.6 10.7 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
3.6 39.1 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
3.5 127.6 GO:0050853 B cell receptor signaling pathway(GO:0050853)
3.5 35.4 GO:0045060 negative thymic T cell selection(GO:0045060)
3.5 10.6 GO:0034696 response to prostaglandin F(GO:0034696)
3.5 17.6 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
3.5 10.6 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
3.5 3.5 GO:0061364 apoptotic process involved in luteolysis(GO:0061364)
3.5 7.0 GO:2000977 regulation of forebrain neuron differentiation(GO:2000977)
3.5 21.0 GO:0015791 polyol transport(GO:0015791)
3.5 27.9 GO:0016191 synaptic vesicle uncoating(GO:0016191)
3.5 7.0 GO:0072061 inner medullary collecting duct development(GO:0072061)
3.5 17.3 GO:0070162 adiponectin secretion(GO:0070162) regulation of adiponectin secretion(GO:0070163) negative regulation of adiponectin secretion(GO:0070164)
3.5 10.4 GO:0010070 zygote asymmetric cell division(GO:0010070)
3.4 31.0 GO:0071985 multivesicular body sorting pathway(GO:0071985)
3.4 10.2 GO:0016199 axon midline choice point recognition(GO:0016199)
3.4 10.2 GO:0036451 cap mRNA methylation(GO:0036451)
3.4 10.1 GO:2000121 regulation of removal of superoxide radicals(GO:2000121)
3.3 16.7 GO:0000706 meiotic DNA double-strand break processing(GO:0000706)
3.3 16.6 GO:0007621 negative regulation of female receptivity(GO:0007621)
3.3 99.4 GO:0030104 water homeostasis(GO:0030104)
3.3 75.7 GO:0071801 regulation of podosome assembly(GO:0071801)
3.3 3.3 GO:0045819 positive regulation of glycogen catabolic process(GO:0045819)
3.3 13.1 GO:0002084 protein depalmitoylation(GO:0002084)
3.3 6.6 GO:0003025 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025)
3.3 9.8 GO:0050854 regulation of antigen receptor-mediated signaling pathway(GO:0050854)
3.3 13.1 GO:0050930 induction of positive chemotaxis(GO:0050930)
3.2 6.5 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
3.2 9.7 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
3.2 12.9 GO:0044725 chromatin reprogramming in the zygote(GO:0044725)
3.2 12.8 GO:0030382 sperm mitochondrion organization(GO:0030382)
3.2 6.4 GO:1905225 regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900736) positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738) response to thyrotropin-releasing hormone(GO:1905225)
3.2 44.6 GO:0015868 purine nucleotide transport(GO:0015865) purine ribonucleotide transport(GO:0015868)
3.2 12.7 GO:0097117 guanylate kinase-associated protein clustering(GO:0097117)
3.2 3.2 GO:0046520 sphingoid biosynthetic process(GO:0046520)
3.2 25.3 GO:0070995 NADPH oxidation(GO:0070995)
3.1 34.6 GO:0019720 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
3.1 9.4 GO:0046060 dATP metabolic process(GO:0046060)
3.1 15.6 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
3.1 46.8 GO:0006517 protein deglycosylation(GO:0006517)
3.1 9.3 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
3.1 9.3 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
3.1 9.3 GO:0034145 positive regulation of toll-like receptor 4 signaling pathway(GO:0034145)
3.1 9.3 GO:0080144 amino acid homeostasis(GO:0080144)
3.1 12.4 GO:0045903 positive regulation of translational fidelity(GO:0045903)
3.1 139.0 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
3.1 9.2 GO:0061009 common bile duct development(GO:0061009)
3.1 27.6 GO:0042415 norepinephrine metabolic process(GO:0042415)
3.0 6.1 GO:0030035 microspike assembly(GO:0030035)
3.0 15.2 GO:1902732 positive regulation of chondrocyte proliferation(GO:1902732)
3.0 9.1 GO:1905146 regulation of protein catabolic process in the vacuole(GO:1904350) lysosomal protein catabolic process(GO:1905146)
3.0 18.1 GO:0046836 glycolipid transport(GO:0046836)
3.0 6.0 GO:1990169 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
3.0 26.9 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
3.0 11.9 GO:0010615 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
3.0 8.9 GO:0002644 negative regulation of tolerance induction(GO:0002644)
3.0 8.9 GO:0072734 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
3.0 8.9 GO:0072156 distal tubule morphogenesis(GO:0072156)
2.9 11.8 GO:0018406 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
2.9 8.8 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
2.9 32.3 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
2.9 14.6 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
2.9 43.6 GO:0031295 T cell costimulation(GO:0031295)
2.9 5.8 GO:0060684 epithelial-mesenchymal cell signaling(GO:0060684)
2.9 11.6 GO:1905007 positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation(GO:1905007)
2.9 5.8 GO:0060534 trachea cartilage development(GO:0060534)
2.8 14.2 GO:0048012 hepatocyte growth factor receptor signaling pathway(GO:0048012)
2.8 5.7 GO:0030327 prenylated protein catabolic process(GO:0030327)
2.8 62.4 GO:0070830 bicellular tight junction assembly(GO:0070830)
2.8 11.3 GO:0072660 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660)
2.8 47.8 GO:0060706 cell differentiation involved in embryonic placenta development(GO:0060706)
2.8 25.3 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
2.8 8.4 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
2.8 72.3 GO:0015701 bicarbonate transport(GO:0015701)
2.8 22.1 GO:0071267 amino acid salvage(GO:0043102) L-methionine salvage(GO:0071267)
2.8 5.5 GO:0060449 bud elongation involved in lung branching(GO:0060449)
2.8 8.3 GO:0045607 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
2.7 35.7 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
2.7 2.7 GO:0071874 response to norepinephrine(GO:0071873) cellular response to norepinephrine stimulus(GO:0071874)
2.7 10.9 GO:0038180 nerve growth factor signaling pathway(GO:0038180)
2.7 27.3 GO:0006590 thyroid hormone generation(GO:0006590)
2.7 40.4 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
2.7 2.7 GO:0009912 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
2.7 5.4 GO:0061366 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
2.7 45.5 GO:0042737 drug catabolic process(GO:0042737)
2.7 5.3 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
2.7 5.3 GO:1901674 histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674)
2.7 10.6 GO:0010624 regulation of Schwann cell proliferation(GO:0010624)
2.6 5.3 GO:0002887 negative regulation of myeloid leukocyte mediated immunity(GO:0002887)
2.6 23.7 GO:0003084 positive regulation of systemic arterial blood pressure(GO:0003084)
2.6 23.7 GO:0034214 protein hexamerization(GO:0034214)
2.6 7.9 GO:0060821 inactivation of X chromosome by DNA methylation(GO:0060821)
2.6 7.9 GO:0030889 negative regulation of B cell proliferation(GO:0030889)
2.6 31.4 GO:0071280 cellular response to copper ion(GO:0071280)
2.6 2.6 GO:0033864 positive regulation of NAD(P)H oxidase activity(GO:0033864)
2.6 7.8 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
2.6 10.4 GO:0008063 Toll signaling pathway(GO:0008063)
2.6 36.5 GO:0009435 NAD biosynthetic process(GO:0009435)
2.6 5.2 GO:0034140 negative regulation of toll-like receptor 3 signaling pathway(GO:0034140)
2.6 18.2 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
2.6 7.8 GO:0001780 neutrophil homeostasis(GO:0001780)
2.6 10.4 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
2.6 5.2 GO:0061724 lipophagy(GO:0061724) negative regulation of exosomal secretion(GO:1903542)
2.6 38.6 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
2.6 28.3 GO:0097119 postsynaptic density protein 95 clustering(GO:0097119)
2.6 5.1 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
2.6 7.7 GO:0060355 positive regulation of cell adhesion molecule production(GO:0060355)
2.6 5.1 GO:0052564 response to immune response of other organism involved in symbiotic interaction(GO:0052564) response to host immune response(GO:0052572)
2.5 10.2 GO:0001913 T cell mediated cytotoxicity(GO:0001913)
2.5 2.5 GO:0034134 toll-like receptor 2 signaling pathway(GO:0034134)
2.5 5.0 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773)
2.5 25.2 GO:0070314 G1 to G0 transition(GO:0070314)
2.5 7.5 GO:0072086 specification of loop of Henle identity(GO:0072086)
2.5 5.0 GO:0042891 antibiotic transport(GO:0042891)
2.5 5.0 GO:0034312 diol metabolic process(GO:0034311) diol biosynthetic process(GO:0034312)
2.5 7.5 GO:2000644 regulation of receptor catabolic process(GO:2000644)
2.5 34.9 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
2.5 9.9 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
2.5 4.9 GO:0038001 paracrine signaling(GO:0038001)
2.4 19.6 GO:0046174 polyol catabolic process(GO:0046174)
2.4 12.2 GO:0048318 axial mesoderm development(GO:0048318)
2.4 12.1 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
2.4 7.2 GO:0006529 asparagine biosynthetic process(GO:0006529)
2.4 7.2 GO:0061091 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
2.4 7.2 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
2.4 16.7 GO:0051256 mitotic spindle elongation(GO:0000022) mitotic spindle midzone assembly(GO:0051256)
2.4 14.2 GO:0048194 Golgi vesicle budding(GO:0048194)
2.4 9.5 GO:0042339 keratan sulfate metabolic process(GO:0042339)
2.4 7.1 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
2.4 4.7 GO:0018199 peptidyl-glutamine modification(GO:0018199)
2.4 9.4 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
2.4 11.8 GO:0071918 urea transport(GO:0015840) urea transmembrane transport(GO:0071918)
2.3 4.7 GO:0050893 sensory processing(GO:0050893)
2.3 30.2 GO:0046069 cGMP catabolic process(GO:0046069)
2.3 4.6 GO:0021540 corpus callosum morphogenesis(GO:0021540)
2.3 13.9 GO:0010668 ectodermal cell differentiation(GO:0010668)
2.3 23.2 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
2.3 4.6 GO:0070859 positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253)
2.3 15.9 GO:0006957 complement activation, alternative pathway(GO:0006957)
2.3 36.4 GO:0042832 defense response to protozoan(GO:0042832)
2.3 27.3 GO:0072673 lamellipodium morphogenesis(GO:0072673)
2.3 2.3 GO:1902514 regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
2.3 4.5 GO:0045054 constitutive secretory pathway(GO:0045054)
2.2 6.7 GO:0060279 positive regulation of ovulation(GO:0060279)
2.2 4.5 GO:1904009 cellular response to monosodium glutamate(GO:1904009)
2.2 26.8 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
2.2 2.2 GO:0032077 positive regulation of deoxyribonuclease activity(GO:0032077)
2.2 8.9 GO:0046462 monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
2.2 86.4 GO:0090662 ATP hydrolysis coupled transmembrane transport(GO:0090662)
2.2 6.6 GO:0010635 regulation of mitochondrial fusion(GO:0010635) negative regulation of mitochondrial fusion(GO:0010637)
2.2 8.8 GO:0045112 integrin biosynthetic process(GO:0045112) regulation of integrin biosynthetic process(GO:0045113)
2.2 17.5 GO:0072015 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
2.2 32.8 GO:0002675 positive regulation of acute inflammatory response(GO:0002675)
2.2 2.2 GO:0035983 response to trichostatin A(GO:0035983) cellular response to trichostatin A(GO:0035984)
2.2 8.7 GO:0019372 lipoxygenase pathway(GO:0019372)
2.2 2.2 GO:0010870 positive regulation of receptor biosynthetic process(GO:0010870)
2.2 4.3 GO:0044268 multicellular organismal protein metabolic process(GO:0044268)
2.2 8.7 GO:0032071 regulation of endodeoxyribonuclease activity(GO:0032071)
2.2 8.7 GO:0051643 endoplasmic reticulum localization(GO:0051643)
2.1 10.7 GO:1903715 regulation of aerobic respiration(GO:1903715)
2.1 2.1 GO:0071245 cellular response to carbon monoxide(GO:0071245)
2.1 8.6 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
2.1 6.4 GO:1904646 cellular response to beta-amyloid(GO:1904646)
2.1 8.5 GO:0015811 L-cystine transport(GO:0015811)
2.1 17.0 GO:0034143 regulation of toll-like receptor 4 signaling pathway(GO:0034143) negative regulation of toll-like receptor 4 signaling pathway(GO:0034144)
2.1 46.5 GO:0019835 cytolysis(GO:0019835)
2.1 19.0 GO:0009143 nucleoside triphosphate catabolic process(GO:0009143)
2.1 22.9 GO:0015732 prostaglandin transport(GO:0015732)
2.1 16.7 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
2.1 4.2 GO:0061684 chaperone-mediated autophagy(GO:0061684)
2.1 14.5 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
2.1 6.2 GO:0002380 immunoglobulin secretion involved in immune response(GO:0002380)
2.1 10.4 GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
2.1 6.2 GO:0006649 phospholipid transfer to membrane(GO:0006649)
2.1 220.5 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
2.0 10.2 GO:0034242 negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
2.0 14.3 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
2.0 4.1 GO:0008078 mesodermal cell migration(GO:0008078)
2.0 12.2 GO:0034058 endosomal vesicle fusion(GO:0034058)
2.0 73.0 GO:0045576 mast cell activation(GO:0045576)
2.0 10.1 GO:0006677 glycosylceramide metabolic process(GO:0006677)
2.0 36.3 GO:0061157 mRNA destabilization(GO:0061157)
2.0 8.1 GO:0089700 protein kinase D signaling(GO:0089700)
2.0 2.0 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
2.0 4.0 GO:0051933 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
2.0 8.1 GO:0060536 cartilage morphogenesis(GO:0060536)
2.0 14.1 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
2.0 8.0 GO:0030210 heparin biosynthetic process(GO:0030210)
2.0 12.0 GO:0009405 pathogenesis(GO:0009405)
2.0 35.9 GO:0001573 ganglioside metabolic process(GO:0001573)
2.0 21.9 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
2.0 7.9 GO:0070560 protein secretion by platelet(GO:0070560)
2.0 7.9 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
2.0 21.7 GO:0007202 activation of phospholipase C activity(GO:0007202)
2.0 9.8 GO:0042256 mature ribosome assembly(GO:0042256)
2.0 9.8 GO:0072678 T cell migration(GO:0072678)
2.0 3.9 GO:1905232 cellular response to L-glutamate(GO:1905232)
1.9 9.7 GO:0023021 termination of signal transduction(GO:0023021)
1.9 13.6 GO:0090308 regulation of methylation-dependent chromatin silencing(GO:0090308)
1.9 5.8 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
1.9 7.7 GO:0015691 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
1.9 1.9 GO:0034124 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
1.9 3.8 GO:0045869 negative regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045869)
1.9 13.4 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
1.9 13.4 GO:0003374 dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374)
1.9 3.8 GO:0046968 cytosol to ER transport(GO:0046967) peptide antigen transport(GO:0046968)
1.9 9.4 GO:0033572 transferrin transport(GO:0033572)
1.9 26.3 GO:0006198 cAMP catabolic process(GO:0006198)
1.9 3.8 GO:0032494 response to peptidoglycan(GO:0032494)
1.9 22.5 GO:0015914 phospholipid transport(GO:0015914)
1.9 3.7 GO:0007356 thorax and anterior abdomen determination(GO:0007356)
1.9 3.7 GO:1904760 myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760)
1.9 15.0 GO:0035729 cellular response to hepatocyte growth factor stimulus(GO:0035729)
1.9 37.4 GO:0006855 drug transmembrane transport(GO:0006855)
1.9 20.6 GO:0001887 selenium compound metabolic process(GO:0001887)
1.9 1.9 GO:0001781 neutrophil apoptotic process(GO:0001781) regulation of neutrophil apoptotic process(GO:0033029)
1.9 5.6 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
1.9 1.9 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
1.8 9.1 GO:0045838 positive regulation of membrane potential(GO:0045838)
1.8 12.8 GO:0002326 B cell lineage commitment(GO:0002326)
1.8 7.3 GO:0006013 mannose metabolic process(GO:0006013)
1.8 7.3 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
1.8 7.3 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023)
1.8 5.4 GO:0002329 pre-B cell differentiation(GO:0002329)
1.8 1.8 GO:0043615 astrocyte cell migration(GO:0043615)
1.8 5.4 GO:0006227 dUDP biosynthetic process(GO:0006227) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) deoxyribonucleoside diphosphate biosynthetic process(GO:0009189) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) dUDP metabolic process(GO:0046077)
1.8 9.0 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
1.8 9.0 GO:0036089 cleavage furrow formation(GO:0036089)
1.8 38.9 GO:0061245 establishment or maintenance of apical/basal cell polarity(GO:0035088) establishment or maintenance of bipolar cell polarity(GO:0061245)
1.8 7.0 GO:0050852 T cell receptor signaling pathway(GO:0050852)
1.7 10.5 GO:0008611 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) cellular lipid biosynthetic process(GO:0097384) ether biosynthetic process(GO:1901503)
1.7 10.5 GO:0046514 ceramide catabolic process(GO:0046514)
1.7 15.7 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
1.7 3.5 GO:0045959 negative regulation of complement activation, classical pathway(GO:0045959)
1.7 5.2 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
1.7 10.3 GO:0071397 cellular response to cholesterol(GO:0071397)
1.7 18.9 GO:0051593 response to folic acid(GO:0051593)
1.7 15.5 GO:0099562 maintenance of postsynaptic specialization structure(GO:0098880) maintenance of postsynaptic density structure(GO:0099562)
1.7 17.1 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
1.7 1.7 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
1.7 3.4 GO:0061181 regulation of chondrocyte development(GO:0061181)
1.7 10.2 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
1.7 5.1 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
1.7 8.4 GO:0071557 histone H3-K27 demethylation(GO:0071557)
1.7 3.4 GO:1900272 negative regulation of long-term synaptic potentiation(GO:1900272)
1.7 3.4 GO:0002215 defense response to nematode(GO:0002215)
1.7 72.1 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
1.7 6.7 GO:0070842 aggresome assembly(GO:0070842)
1.7 15.1 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
1.7 25.1 GO:0006895 Golgi to endosome transport(GO:0006895)
1.7 16.7 GO:0042182 ketone catabolic process(GO:0042182)
1.7 5.0 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
1.7 14.9 GO:0061042 vascular wound healing(GO:0061042)
1.7 16.6 GO:0033127 regulation of histone phosphorylation(GO:0033127)
1.7 6.6 GO:0032919 spermine acetylation(GO:0032919)
1.7 16.5 GO:0043252 sodium-independent organic anion transport(GO:0043252)
1.7 6.6 GO:1903576 response to L-arginine(GO:1903576)
1.6 13.2 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
1.6 14.8 GO:0052697 xenobiotic glucuronidation(GO:0052697)
1.6 4.9 GO:2001183 negative regulation of interleukin-12 secretion(GO:2001183)
1.6 3.3 GO:2001038 regulation of cellular response to drug(GO:2001038)
1.6 6.5 GO:0001783 B cell apoptotic process(GO:0001783)
1.6 3.3 GO:0043418 homocysteine catabolic process(GO:0043418)
1.6 9.7 GO:0010838 positive regulation of keratinocyte proliferation(GO:0010838)
1.6 1.6 GO:1903977 positive regulation of glial cell migration(GO:1903977)
1.6 1.6 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
1.6 8.0 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
1.6 6.4 GO:0015801 aromatic amino acid transport(GO:0015801)
1.6 4.8 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
1.6 6.3 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
1.6 4.7 GO:0051660 establishment of centrosome localization(GO:0051660)
1.6 3.1 GO:0006579 amino-acid betaine catabolic process(GO:0006579)
1.5 15.5 GO:0060512 prostate gland morphogenesis(GO:0060512)
1.5 20.1 GO:0006972 hyperosmotic response(GO:0006972)
1.5 3.1 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
1.5 6.2 GO:0097332 response to antipsychotic drug(GO:0097332)
1.5 1.5 GO:0043382 positive regulation of memory T cell differentiation(GO:0043382)
1.5 3.1 GO:0031585 regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031585)
1.5 30.6 GO:0006308 DNA catabolic process(GO:0006308)
1.5 19.9 GO:0032814 regulation of natural killer cell activation(GO:0032814)
1.5 7.6 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
1.5 4.6 GO:0032484 Ral protein signal transduction(GO:0032484)
1.5 4.5 GO:0045357 interferon-beta biosynthetic process(GO:0045350) regulation of interferon-beta biosynthetic process(GO:0045357)
1.5 31.7 GO:0007257 activation of JUN kinase activity(GO:0007257)
1.5 4.5 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
1.5 9.0 GO:0042492 gamma-delta T cell differentiation(GO:0042492)
1.5 10.4 GO:0098903 regulation of membrane repolarization during action potential(GO:0098903)
1.5 10.4 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
1.5 4.4 GO:1901844 regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844)
1.5 3.0 GO:0009756 carbohydrate mediated signaling(GO:0009756) hexose mediated signaling(GO:0009757) sugar mediated signaling pathway(GO:0010182) glucose mediated signaling pathway(GO:0010255)
1.5 26.6 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
1.5 8.9 GO:0097435 fibril organization(GO:0097435)
1.5 1.5 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
1.5 48.7 GO:0018345 protein palmitoylation(GO:0018345)
1.5 1.5 GO:0061588 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
1.5 5.9 GO:0001582 detection of chemical stimulus involved in sensory perception of sweet taste(GO:0001582)
1.5 2.9 GO:0072602 interleukin-4 secretion(GO:0072602)
1.5 10.2 GO:0030225 macrophage differentiation(GO:0030225)
1.5 4.4 GO:0048263 determination of dorsal identity(GO:0048263)
1.4 1.4 GO:0006272 leading strand elongation(GO:0006272)
1.4 13.0 GO:0071294 cellular response to zinc ion(GO:0071294)
1.4 15.8 GO:0030033 microvillus assembly(GO:0030033)
1.4 5.7 GO:0097680 double-strand break repair via classical nonhomologous end joining(GO:0097680)
1.4 17.2 GO:0006525 arginine metabolic process(GO:0006525)
1.4 47.2 GO:0008333 endosome to lysosome transport(GO:0008333)
1.4 7.1 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
1.4 14.3 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
1.4 4.3 GO:0071929 alpha-tubulin acetylation(GO:0071929)
1.4 58.4 GO:0044380 protein localization to cytoskeleton(GO:0044380)
1.4 19.9 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
1.4 2.8 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
1.4 1.4 GO:0035627 ceramide transport(GO:0035627)
1.4 40.7 GO:0030593 neutrophil chemotaxis(GO:0030593)
1.4 4.2 GO:0032058 positive regulation of translational initiation in response to stress(GO:0032058)
1.4 19.6 GO:0014044 Schwann cell development(GO:0014044)
1.4 71.4 GO:0050830 defense response to Gram-positive bacterium(GO:0050830)
1.4 1.4 GO:0038128 ERBB2 signaling pathway(GO:0038128)
1.4 19.6 GO:0045066 regulatory T cell differentiation(GO:0045066)
1.4 7.0 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
1.4 23.6 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
1.4 4.2 GO:0043321 regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
1.4 4.2 GO:0090289 apoptotic process in bone marrow(GO:0071839) regulation of osteoclast proliferation(GO:0090289)
1.4 2.8 GO:0030908 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
1.4 8.2 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
1.4 5.5 GO:1901298 hydrogen peroxide-mediated programmed cell death(GO:0010421) programmed cell death in response to reactive oxygen species(GO:0097468) regulation of hydrogen peroxide-mediated programmed cell death(GO:1901298)
1.4 13.7 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
1.4 5.5 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
1.4 13.6 GO:0045332 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
1.4 17.7 GO:0002250 adaptive immune response(GO:0002250)
1.3 4.0 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
1.3 4.0 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902) negative regulation of membrane depolarization(GO:1904180)
1.3 4.0 GO:0043129 surfactant homeostasis(GO:0043129)
1.3 2.7 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
1.3 2.7 GO:0010911 regulation of isomerase activity(GO:0010911) positive regulation of isomerase activity(GO:0010912) regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373)
1.3 2.7 GO:0002741 positive regulation of cytokine secretion involved in immune response(GO:0002741)
1.3 11.8 GO:0010919 regulation of inositol phosphate biosynthetic process(GO:0010919) positive regulation of inositol phosphate biosynthetic process(GO:0060732)
1.3 11.7 GO:0019934 cGMP-mediated signaling(GO:0019934)
1.3 67.6 GO:0030183 B cell differentiation(GO:0030183)
1.3 3.9 GO:0071386 cellular response to corticosterone stimulus(GO:0071386)
1.3 20.6 GO:0046339 diacylglycerol metabolic process(GO:0046339)
1.3 14.2 GO:0014052 regulation of gamma-aminobutyric acid secretion(GO:0014052)
1.3 9.0 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
1.3 8.9 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
1.3 1.3 GO:0051797 regulation of hair follicle development(GO:0051797)
1.3 3.8 GO:1903575 cornified envelope assembly(GO:1903575)
1.3 2.5 GO:0045683 negative regulation of epidermis development(GO:0045683)
1.3 11.4 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
1.3 1.3 GO:0075509 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
1.3 5.0 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
1.3 2.5 GO:0016080 synaptic vesicle targeting(GO:0016080)
1.3 15.1 GO:0070933 histone H4 deacetylation(GO:0070933)
1.3 16.3 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
1.2 2.5 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
1.2 3.7 GO:1902254 negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902254)
1.2 11.2 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
1.2 5.0 GO:2000253 positive regulation of feeding behavior(GO:2000253)
1.2 1.2 GO:0045658 regulation of neutrophil differentiation(GO:0045658)
1.2 6.2 GO:0031640 killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364)
1.2 2.5 GO:0045351 type I interferon biosynthetic process(GO:0045351)
1.2 6.1 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
1.2 9.8 GO:0048149 behavioral response to ethanol(GO:0048149)
1.2 4.9 GO:0034421 post-translational protein acetylation(GO:0034421)
1.2 45.1 GO:1900046 regulation of blood coagulation(GO:0030193) regulation of hemostasis(GO:1900046)
1.2 1.2 GO:0002913 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
1.2 7.2 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
1.2 7.2 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
1.2 1.2 GO:0001828 inner cell mass cellular morphogenesis(GO:0001828)
1.2 9.6 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
1.2 7.2 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
1.2 19.2 GO:0006661 phosphatidylinositol biosynthetic process(GO:0006661)
1.2 13.1 GO:0090382 phagosome maturation(GO:0090382)
1.2 7.2 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
1.2 6.0 GO:0021683 cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
1.2 3.6 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
1.2 5.9 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
1.2 2.4 GO:0071718 sodium-independent icosanoid transport(GO:0071718)
1.2 1.2 GO:0048294 negative regulation of isotype switching to IgE isotypes(GO:0048294)
1.2 3.5 GO:0045723 positive regulation of fatty acid biosynthetic process(GO:0045723)
1.2 60.8 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
1.2 14.0 GO:0035067 negative regulation of histone acetylation(GO:0035067)
1.2 3.5 GO:0051697 protein delipidation(GO:0051697)
1.2 7.0 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
1.2 33.7 GO:0035987 endodermal cell differentiation(GO:0035987)
1.2 8.1 GO:0014886 transition between slow and fast fiber(GO:0014886)
1.1 1.1 GO:0010454 negative regulation of cell fate commitment(GO:0010454)
1.1 3.4 GO:2000774 positive regulation of cellular senescence(GO:2000774)
1.1 3.4 GO:0043324 eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474) rhodopsin metabolic process(GO:0046154)
1.1 3.4 GO:0009758 carbohydrate utilization(GO:0009758)
1.1 2.3 GO:0019348 dolichol metabolic process(GO:0019348)
1.1 3.4 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
1.1 18.3 GO:0043507 positive regulation of JUN kinase activity(GO:0043507)
1.1 2.3 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
1.1 3.4 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
1.1 5.6 GO:0071409 cellular response to cycloheximide(GO:0071409)
1.1 4.5 GO:0030311 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
1.1 5.6 GO:0017121 phospholipid scrambling(GO:0017121)
1.1 2.2 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
1.1 36.7 GO:0046839 phospholipid dephosphorylation(GO:0046839)
1.1 4.4 GO:1904354 negative regulation of telomere capping(GO:1904354)
1.1 11.0 GO:0036065 fucosylation(GO:0036065)
1.1 1.1 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
1.1 2.2 GO:0015820 leucine transport(GO:0015820)
1.1 2.2 GO:1903525 regulation of membrane tubulation(GO:1903525)
1.1 13.1 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
1.1 2.2 GO:1903976 negative regulation of glial cell migration(GO:1903976)
1.1 9.8 GO:0042559 pteridine-containing compound biosynthetic process(GO:0042559)
1.1 2.2 GO:0070375 ERK5 cascade(GO:0070375)
1.1 6.5 GO:2001270 regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
1.1 3.2 GO:0009133 nucleoside diphosphate biosynthetic process(GO:0009133)
1.1 4.3 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
1.1 69.0 GO:0019882 antigen processing and presentation(GO:0019882)
1.1 5.4 GO:0071318 cellular response to ATP(GO:0071318)
1.1 25.7 GO:0002260 lymphocyte homeostasis(GO:0002260)
1.1 6.4 GO:0042148 strand invasion(GO:0042148)
1.1 7.5 GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
1.1 2.1 GO:0030299 intestinal cholesterol absorption(GO:0030299)
1.1 3.2 GO:0070343 white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350)
1.1 3.2 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
1.1 13.8 GO:0070228 regulation of lymphocyte apoptotic process(GO:0070228)
1.1 7.4 GO:0002861 regulation of inflammatory response to antigenic stimulus(GO:0002861)
1.1 10.6 GO:0045002 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002)
1.1 15.9 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
1.1 2.1 GO:1902336 positive regulation of retinal ganglion cell axon guidance(GO:1902336)
1.1 34.0 GO:0006505 GPI anchor metabolic process(GO:0006505)
1.1 4.2 GO:0042635 positive regulation of hair cycle(GO:0042635)
1.0 4.2 GO:0040033 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
1.0 22.0 GO:0009225 nucleotide-sugar metabolic process(GO:0009225)
1.0 10.4 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
1.0 3.1 GO:0039530 MDA-5 signaling pathway(GO:0039530)
1.0 3.1 GO:0035754 B cell chemotaxis(GO:0035754)
1.0 5.2 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
1.0 7.3 GO:0035455 response to interferon-alpha(GO:0035455)
1.0 3.1 GO:0071494 cellular response to UV-C(GO:0071494)
1.0 1.0 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
1.0 4.1 GO:0001579 medium-chain fatty acid transport(GO:0001579)
1.0 11.3 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
1.0 1.0 GO:2000053 regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053)
1.0 6.1 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
1.0 7.1 GO:0031643 positive regulation of myelination(GO:0031643)
1.0 2.0 GO:0021678 third ventricle development(GO:0021678)
1.0 23.2 GO:0051453 regulation of intracellular pH(GO:0051453)
1.0 1.0 GO:0032056 positive regulation of translation in response to stress(GO:0032056)
1.0 2.0 GO:1904796 regulation of core promoter binding(GO:1904796) positive regulation of core promoter binding(GO:1904798)
1.0 22.0 GO:0014003 oligodendrocyte development(GO:0014003)
1.0 2.0 GO:0042908 xenobiotic transport(GO:0042908)
1.0 2.0 GO:0001866 NK T cell proliferation(GO:0001866)
1.0 2.9 GO:0032218 riboflavin transport(GO:0032218)
1.0 2.9 GO:0002692 negative regulation of cellular extravasation(GO:0002692)
1.0 2.9 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
1.0 18.5 GO:0045806 negative regulation of endocytosis(GO:0045806)
1.0 1.9 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
1.0 1.9 GO:0021530 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
1.0 8.7 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
1.0 1.0 GO:0034146 toll-like receptor 5 signaling pathway(GO:0034146)
1.0 6.7 GO:0035879 plasma membrane lactate transport(GO:0035879)
1.0 4.8 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
1.0 1.9 GO:1900118 negative regulation of execution phase of apoptosis(GO:1900118)
1.0 5.7 GO:0038169 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
1.0 2.9 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
1.0 11.4 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
1.0 2.9 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.9 6.6 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.9 5.7 GO:0090367 regulation of mRNA modification(GO:0090365) negative regulation of mRNA modification(GO:0090367)
0.9 9.4 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.9 1.9 GO:2001166 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.9 3.7 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
0.9 7.4 GO:0030903 notochord development(GO:0030903)
0.9 4.6 GO:0042659 regulation of cell fate specification(GO:0042659)
0.9 3.7 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.9 15.5 GO:0007032 endosome organization(GO:0007032)
0.9 31.7 GO:0016126 sterol biosynthetic process(GO:0016126)
0.9 4.5 GO:0030853 negative regulation of granulocyte differentiation(GO:0030853)
0.9 4.5 GO:0019471 4-hydroxyproline metabolic process(GO:0019471)
0.9 4.5 GO:0032757 positive regulation of interleukin-8 production(GO:0032757)
0.9 18.9 GO:0002687 positive regulation of leukocyte migration(GO:0002687)
0.9 14.4 GO:0006911 phagocytosis, engulfment(GO:0006911)
0.9 6.3 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.9 5.4 GO:0070327 thyroid hormone transport(GO:0070327)
0.9 3.6 GO:0035336 long-chain fatty-acyl-CoA metabolic process(GO:0035336)
0.9 3.6 GO:0007220 Notch receptor processing(GO:0007220)
0.9 12.4 GO:0090280 positive regulation of calcium ion import(GO:0090280)
0.9 15.0 GO:0006730 one-carbon metabolic process(GO:0006730)
0.9 15.0 GO:0006958 complement activation, classical pathway(GO:0006958)
0.9 0.9 GO:0060017 parathyroid gland development(GO:0060017)
0.9 1.7 GO:2001268 negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
0.9 2.6 GO:0031053 primary miRNA processing(GO:0031053)
0.9 17.2 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.9 2.6 GO:0046833 positive regulation of RNA export from nucleus(GO:0046833)
0.9 5.1 GO:0060318 regulation of definitive erythrocyte differentiation(GO:0010724) definitive erythrocyte differentiation(GO:0060318)
0.9 6.8 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.8 5.1 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.8 109.0 GO:0006898 receptor-mediated endocytosis(GO:0006898)
0.8 4.2 GO:0010815 bradykinin catabolic process(GO:0010815)
0.8 6.7 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.8 5.8 GO:0038179 neurotrophin signaling pathway(GO:0038179)
0.8 10.0 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.8 1.7 GO:1901722 regulation of cell proliferation involved in kidney development(GO:1901722)
0.8 6.6 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.8 2.5 GO:0045061 thymic T cell selection(GO:0045061)
0.8 1.7 GO:0090283 regulation of protein glycosylation in Golgi(GO:0090283)
0.8 3.3 GO:0030917 midbrain-hindbrain boundary development(GO:0030917)
0.8 1.6 GO:0034349 glial cell apoptotic process(GO:0034349)
0.8 4.1 GO:0001921 positive regulation of receptor recycling(GO:0001921)
0.8 8.2 GO:1902743 regulation of lamellipodium organization(GO:1902743)
0.8 4.1 GO:0045730 respiratory burst(GO:0045730)
0.8 2.4 GO:0080009 mRNA methylation(GO:0080009)
0.8 6.4 GO:0017145 stem cell division(GO:0017145)
0.8 2.4 GO:2000696 regulation of epithelial cell differentiation involved in kidney development(GO:2000696)
0.8 0.8 GO:0072102 glomerulus morphogenesis(GO:0072102)
0.8 39.8 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.8 1.6 GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway(GO:0010804)
0.8 57.0 GO:1902017 regulation of cilium assembly(GO:1902017)
0.8 3.2 GO:1904322 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.8 3.1 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074) positive regulation of phospholipid biosynthetic process(GO:0071073)
0.8 23.4 GO:0018149 peptide cross-linking(GO:0018149)
0.8 0.8 GO:1904908 negative regulation of maintenance of sister chromatid cohesion(GO:0034092) negative regulation of maintenance of mitotic sister chromatid cohesion(GO:0034183) maintenance of mitotic sister chromatid cohesion, telomeric(GO:0099403) mitotic sister chromatid cohesion, telomeric(GO:0099404) regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904907) negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904908)
0.8 5.4 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.8 9.3 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.8 23.1 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.7 1.5 GO:0061188 regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
0.7 3.7 GO:0051601 exocyst localization(GO:0051601)
0.7 5.9 GO:0046579 positive regulation of Ras protein signal transduction(GO:0046579)
0.7 2.9 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.7 3.7 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.7 10.2 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.7 0.7 GO:0048842 positive regulation of axon extension involved in axon guidance(GO:0048842)
0.7 3.6 GO:0016078 tRNA catabolic process(GO:0016078)
0.7 4.2 GO:0031284 regulation of guanylate cyclase activity(GO:0031282) positive regulation of guanylate cyclase activity(GO:0031284)
0.7 2.1 GO:0006543 glutamine catabolic process(GO:0006543)
0.7 3.4 GO:0019521 aldonic acid metabolic process(GO:0019520) D-gluconate metabolic process(GO:0019521)
0.7 2.7 GO:0072530 purine-containing compound transmembrane transport(GO:0072530)
0.7 1.4 GO:0042756 drinking behavior(GO:0042756)
0.7 5.4 GO:0046116 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.7 3.4 GO:0048505 regulation of timing of cell differentiation(GO:0048505)
0.7 2.0 GO:0021590 cerebellum maturation(GO:0021590) cerebellar cortex maturation(GO:0021699)
0.7 2.0 GO:0033262 regulation of nuclear cell cycle DNA replication(GO:0033262)
0.7 4.0 GO:0060143 positive regulation of syncytium formation by plasma membrane fusion(GO:0060143)
0.7 10.7 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.7 1.3 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.7 5.3 GO:0048733 sebaceous gland development(GO:0048733)
0.7 18.4 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.7 2.0 GO:0033385 geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384) geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386) farnesyl diphosphate biosynthetic process(GO:0045337)
0.7 2.0 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.7 5.2 GO:0060965 negative regulation of gene silencing by miRNA(GO:0060965)
0.6 3.2 GO:0060770 epithelial cell proliferation involved in prostate gland development(GO:0060767) regulation of epithelial cell proliferation involved in prostate gland development(GO:0060768) negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.6 1.9 GO:0032506 cytokinetic process(GO:0032506)
0.6 7.1 GO:0071285 cellular response to lithium ion(GO:0071285)
0.6 5.8 GO:0031935 regulation of chromatin silencing(GO:0031935)
0.6 5.8 GO:0031641 regulation of myelination(GO:0031641)
0.6 2.5 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.6 1.9 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.6 8.8 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.6 15.1 GO:0042491 auditory receptor cell differentiation(GO:0042491)
0.6 4.4 GO:0016576 histone dephosphorylation(GO:0016576)
0.6 0.6 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.6 1.2 GO:0045652 regulation of megakaryocyte differentiation(GO:0045652)
0.6 3.7 GO:0099612 protein localization to axon(GO:0099612)
0.6 18.2 GO:1902850 microtubule cytoskeleton organization involved in mitosis(GO:1902850)
0.6 1.8 GO:1900095 random inactivation of X chromosome(GO:0060816) regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.6 4.2 GO:0071364 cellular response to epidermal growth factor stimulus(GO:0071364)
0.6 7.2 GO:0050691 regulation of defense response to virus by host(GO:0050691)
0.6 0.6 GO:0006408 snRNA export from nucleus(GO:0006408)
0.6 13.1 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.6 3.6 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.6 2.4 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.6 1.2 GO:0044791 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.6 59.1 GO:0072659 protein localization to plasma membrane(GO:0072659)
0.6 1.2 GO:1902172 keratinocyte apoptotic process(GO:0097283) regulation of keratinocyte apoptotic process(GO:1902172)
0.6 3.0 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.6 2.9 GO:0060749 mammary gland alveolus development(GO:0060749) mammary gland lobule development(GO:0061377)
0.6 3.5 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.6 22.1 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.6 1.7 GO:0033600 negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.6 1.2 GO:0045105 intermediate filament polymerization or depolymerization(GO:0045105)
0.6 3.5 GO:0042136 neurotransmitter biosynthetic process(GO:0042136)
0.6 0.6 GO:0001773 myeloid dendritic cell activation(GO:0001773)
0.6 2.9 GO:1990592 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.6 1.1 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.6 3.4 GO:0046415 urate metabolic process(GO:0046415)
0.6 1.7 GO:0046098 guanine metabolic process(GO:0046098)
0.6 1.1 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.6 2.3 GO:1904386 response to L-phenylalanine derivative(GO:1904386)
0.6 2.2 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.6 3.9 GO:0001938 positive regulation of endothelial cell proliferation(GO:0001938)
0.5 3.8 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.5 2.2 GO:1900273 positive regulation of long-term synaptic potentiation(GO:1900273)
0.5 14.0 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.5 10.2 GO:0048286 lung alveolus development(GO:0048286)
0.5 1.6 GO:0045920 negative regulation of exocytosis(GO:0045920)
0.5 0.5 GO:0071869 response to catecholamine(GO:0071869)
0.5 0.5 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.5 6.9 GO:0030032 lamellipodium assembly(GO:0030032)
0.5 2.1 GO:0044211 CTP salvage(GO:0044211)
0.5 12.6 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.5 3.1 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.5 4.2 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.5 2.1 GO:0044598 polyketide metabolic process(GO:0030638) aminoglycoside antibiotic metabolic process(GO:0030647) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
0.5 3.1 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.5 6.1 GO:0030574 collagen catabolic process(GO:0030574)
0.5 4.1 GO:0005513 detection of calcium ion(GO:0005513)
0.5 2.0 GO:0033160 positive regulation of protein import into nucleus, translocation(GO:0033160)
0.5 1.0 GO:0010157 response to chlorate(GO:0010157)
0.5 10.7 GO:0006909 phagocytosis(GO:0006909)
0.5 6.1 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.5 1.5 GO:1903232 melanosome assembly(GO:1903232)
0.5 3.5 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.5 21.9 GO:0007599 hemostasis(GO:0007599)
0.5 8.5 GO:0042073 intraciliary transport(GO:0042073)
0.5 1.0 GO:2001170 negative regulation of ATP biosynthetic process(GO:2001170) negative regulation of glucose import in response to insulin stimulus(GO:2001274)
0.5 3.5 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.5 2.0 GO:0071872 cellular response to epinephrine stimulus(GO:0071872)
0.5 3.4 GO:0050710 negative regulation of cytokine secretion(GO:0050710)
0.5 3.4 GO:1903053 regulation of extracellular matrix organization(GO:1903053)
0.5 54.8 GO:0098742 cell-cell adhesion via plasma-membrane adhesion molecules(GO:0098742)
0.5 4.4 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.5 1.5 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.5 3.4 GO:0030259 lipid glycosylation(GO:0030259)
0.5 1.0 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.5 10.7 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.5 1.5 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
0.5 1.0 GO:0035315 hair cell differentiation(GO:0035315)
0.5 1.4 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.5 3.4 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.5 1.4 GO:0015822 ornithine transport(GO:0015822)
0.5 0.9 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.5 4.7 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.5 1.4 GO:1902591 single-organism membrane budding(GO:1902591)
0.5 0.9 GO:0046112 nucleobase biosynthetic process(GO:0046112)
0.5 1.4 GO:0061045 negative regulation of wound healing(GO:0061045)
0.5 6.9 GO:1901998 toxin transport(GO:1901998)
0.5 22.9 GO:0030217 T cell differentiation(GO:0030217)
0.5 0.9 GO:0048333 mesodermal cell differentiation(GO:0048333)
0.5 0.5 GO:0006971 hypotonic response(GO:0006971) cellular hypotonic response(GO:0071476)
0.5 4.5 GO:0070266 necroptotic process(GO:0070266)
0.5 9.5 GO:0050707 regulation of cytokine secretion(GO:0050707)
0.5 3.6 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.4 7.1 GO:0006336 DNA replication-independent nucleosome assembly(GO:0006336)
0.4 0.9 GO:0044068 modulation by symbiont of host cellular process(GO:0044068)
0.4 3.5 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.4 5.7 GO:0006892 post-Golgi vesicle-mediated transport(GO:0006892)
0.4 4.4 GO:0014009 glial cell proliferation(GO:0014009)
0.4 3.4 GO:0071625 vocalization behavior(GO:0071625)
0.4 2.5 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.4 0.4 GO:0048199 vesicle targeting, to, from or within Golgi(GO:0048199)
0.4 17.9 GO:0045216 cell-cell junction organization(GO:0045216)
0.4 1.7 GO:0071169 establishment of protein localization to chromatin(GO:0071169)
0.4 0.4 GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
0.4 2.0 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.4 2.0 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.4 2.0 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.4 4.0 GO:1901409 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407) positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.4 4.0 GO:0051569 regulation of histone H3-K4 methylation(GO:0051569)
0.4 2.0 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.4 2.8 GO:0035634 response to stilbenoid(GO:0035634)
0.4 0.4 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.4 2.7 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.4 1.2 GO:0002225 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antibacterial peptide production(GO:0002803)
0.4 1.6 GO:0010470 regulation of gastrulation(GO:0010470)
0.4 7.0 GO:0006270 DNA replication initiation(GO:0006270)
0.4 10.0 GO:0014065 phosphatidylinositol 3-kinase signaling(GO:0014065)
0.4 2.7 GO:0018377 protein myristoylation(GO:0018377)
0.4 1.9 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.4 0.8 GO:0032703 negative regulation of interleukin-2 production(GO:0032703)
0.4 1.1 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.4 3.7 GO:0098743 cartilage condensation(GO:0001502) cell aggregation(GO:0098743)
0.4 19.5 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.4 2.2 GO:1990035 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.4 1.8 GO:0002002 regulation of angiotensin levels in blood(GO:0002002)
0.4 0.7 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.4 5.7 GO:0046834 lipid phosphorylation(GO:0046834)
0.4 1.8 GO:0000729 DNA double-strand break processing(GO:0000729)
0.4 17.5 GO:0010833 telomere maintenance via telomere lengthening(GO:0010833)
0.4 2.5 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.4 1.8 GO:0001842 neural fold formation(GO:0001842)
0.3 0.3 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.3 3.3 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.3 2.0 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.3 4.0 GO:2000780 negative regulation of double-strand break repair(GO:2000780)
0.3 1.0 GO:0006567 threonine catabolic process(GO:0006567)
0.3 2.6 GO:0031065 positive regulation of histone deacetylation(GO:0031065)
0.3 11.5 GO:0051607 defense response to virus(GO:0051607)
0.3 0.3 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.3 1.3 GO:0007638 mechanosensory behavior(GO:0007638)
0.3 0.6 GO:0046578 regulation of Ras protein signal transduction(GO:0046578)
0.3 0.6 GO:0032474 otolith morphogenesis(GO:0032474)
0.3 4.6 GO:0006379 mRNA cleavage(GO:0006379)
0.3 1.8 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.3 4.9 GO:0033363 secretory granule organization(GO:0033363)
0.3 0.3 GO:1900135 positive regulation of renin secretion into blood stream(GO:1900135)
0.3 1.8 GO:0030157 pancreatic juice secretion(GO:0030157)
0.3 10.5 GO:0051865 protein autoubiquitination(GO:0051865)
0.3 2.4 GO:0001967 suckling behavior(GO:0001967)
0.3 16.4 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.3 2.6 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.3 1.7 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.3 1.1 GO:0010810 regulation of cell-substrate adhesion(GO:0010810)
0.3 3.4 GO:0015816 glycine transport(GO:0015816)
0.3 2.5 GO:0007041 lysosomal transport(GO:0007041)
0.3 2.0 GO:0035329 hippo signaling(GO:0035329)
0.3 3.3 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.3 0.8 GO:0018364 peptidyl-glutamine methylation(GO:0018364) snoRNA localization(GO:0048254)
0.3 1.1 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.3 1.1 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.3 0.3 GO:1990314 cellular response to insulin-like growth factor stimulus(GO:1990314)
0.3 1.1 GO:0043388 positive regulation of DNA binding(GO:0043388)
0.3 2.1 GO:0071025 RNA surveillance(GO:0071025)
0.3 2.8 GO:0003351 epithelial cilium movement(GO:0003351)
0.2 0.7 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.2 0.7 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.2 0.7 GO:0044752 response to human chorionic gonadotropin(GO:0044752)
0.2 2.0 GO:0008340 determination of adult lifespan(GO:0008340)
0.2 2.2 GO:0007603 phototransduction, visible light(GO:0007603)
0.2 1.2 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.2 0.5 GO:0033505 floor plate morphogenesis(GO:0033505)
0.2 2.2 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.2 0.5 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.2 0.5 GO:0016240 autophagosome docking(GO:0016240)
0.2 1.9 GO:0006465 signal peptide processing(GO:0006465)
0.2 0.7 GO:1902895 positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.2 1.4 GO:0006349 regulation of gene expression by genetic imprinting(GO:0006349)
0.2 7.3 GO:0042113 B cell activation(GO:0042113)
0.2 2.3 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.2 1.9 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.2 0.7 GO:0009452 7-methylguanosine RNA capping(GO:0009452) RNA capping(GO:0036260)
0.2 0.5 GO:0033079 immature T cell proliferation(GO:0033079)
0.2 0.9 GO:0046208 spermine catabolic process(GO:0046208)
0.2 1.6 GO:0071359 cellular response to dsRNA(GO:0071359)
0.2 1.5 GO:0046326 positive regulation of glucose import(GO:0046326)
0.2 3.3 GO:0018027 peptidyl-lysine dimethylation(GO:0018027)
0.2 0.9 GO:0097062 dendritic spine maintenance(GO:0097062)
0.2 1.7 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.2 1.7 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.2 4.9 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.2 3.2 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.2 0.8 GO:0007258 JUN phosphorylation(GO:0007258)
0.2 1.0 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.2 2.6 GO:0021983 pituitary gland development(GO:0021983)
0.2 1.4 GO:0010718 positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.2 0.6 GO:0002347 response to tumor cell(GO:0002347)
0.2 1.1 GO:0016926 protein desumoylation(GO:0016926)
0.2 0.9 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.2 1.1 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.2 1.3 GO:0019388 galactose catabolic process(GO:0019388)
0.2 1.6 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.2 0.5 GO:0070092 glucagon secretion(GO:0070091) regulation of glucagon secretion(GO:0070092)
0.2 0.5 GO:0030091 protein repair(GO:0030091)
0.2 5.6 GO:0045089 positive regulation of innate immune response(GO:0045089)
0.2 0.3 GO:1904640 response to methionine(GO:1904640)
0.2 10.7 GO:1902476 chloride transmembrane transport(GO:1902476)
0.2 1.0 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.2 0.6 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.2 0.5 GO:0061743 motor learning(GO:0061743)
0.2 0.2 GO:2001273 regulation of glucose import in response to insulin stimulus(GO:2001273)
0.2 0.3 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.2 24.2 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.2 1.8 GO:0051058 negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058)
0.1 3.0 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.1 0.1 GO:0060701 negative regulation of ribonuclease activity(GO:0060701) negative regulation of endoribonuclease activity(GO:0060702)
0.1 1.2 GO:0034310 ethanol catabolic process(GO:0006068) primary alcohol catabolic process(GO:0034310)
0.1 1.1 GO:1902259 regulation of delayed rectifier potassium channel activity(GO:1902259)
0.1 0.5 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.1 0.3 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.1 0.4 GO:0014856 skeletal muscle cell proliferation(GO:0014856)
0.1 0.8 GO:0000012 single strand break repair(GO:0000012)
0.1 0.5 GO:0006983 ER overload response(GO:0006983)
0.1 0.9 GO:0007616 long-term memory(GO:0007616)
0.1 0.3 GO:0036119 response to platelet-derived growth factor(GO:0036119)
0.1 0.5 GO:1904294 positive regulation of ERAD pathway(GO:1904294)
0.1 0.3 GO:0036010 protein localization to endosome(GO:0036010)
0.1 0.3 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.1 1.1 GO:0048015 phosphatidylinositol-mediated signaling(GO:0048015) inositol lipid-mediated signaling(GO:0048017)
0.1 0.7 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 1.0 GO:0060479 lung cell differentiation(GO:0060479) lung epithelial cell differentiation(GO:0060487)
0.1 0.2 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.1 0.9 GO:0051703 social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.1 0.4 GO:0046341 CDP-diacylglycerol biosynthetic process(GO:0016024) CDP-diacylglycerol metabolic process(GO:0046341)
0.1 0.2 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.1 1.8 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.1 0.6 GO:2000647 negative regulation of stem cell proliferation(GO:2000647)
0.1 0.3 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.1 0.1 GO:0010519 negative regulation of phospholipase activity(GO:0010519)
0.1 2.7 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 0.9 GO:0001825 blastocyst formation(GO:0001825)
0.1 1.0 GO:0021591 ventricular system development(GO:0021591)
0.1 0.3 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.1 0.1 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.0 0.3 GO:0010842 retina layer formation(GO:0010842)
0.0 9.0 GO:0043087 regulation of GTPase activity(GO:0043087)
0.0 0.4 GO:0030497 fatty acid elongation(GO:0030497)
0.0 0.1 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448)
0.0 0.1 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.1 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.0 0.2 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 0.0 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.0 0.1 GO:0048490 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.2 GO:0034620 cellular response to unfolded protein(GO:0034620)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
47.8 238.9 GO:0061689 tricellular tight junction(GO:0061689)
40.0 960.0 GO:0016327 apicolateral plasma membrane(GO:0016327)
33.6 134.4 GO:0005607 laminin-2 complex(GO:0005607)
25.2 75.7 GO:0034667 integrin alpha3-beta1 complex(GO:0034667)
16.3 65.2 GO:0071438 invadopodium membrane(GO:0071438)
13.7 41.1 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
13.4 40.1 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
13.3 39.9 GO:0031308 intrinsic component of nuclear outer membrane(GO:0031308) integral component of nuclear outer membrane(GO:0031309)
13.2 39.6 GO:0032398 MHC class Ib protein complex(GO:0032398)
12.7 139.7 GO:0016342 catenin complex(GO:0016342)
10.7 85.8 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
10.6 84.6 GO:0044194 cytolytic granule(GO:0044194)
10.4 31.2 GO:0036488 CHOP-C/EBP complex(GO:0036488)
10.3 51.3 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
10.1 101.0 GO:0042101 T cell receptor complex(GO:0042101)
9.8 48.9 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
9.0 27.1 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
8.9 8.9 GO:0005945 6-phosphofructokinase complex(GO:0005945)
8.9 44.4 GO:0048179 activin receptor complex(GO:0048179)
8.7 26.2 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
8.7 26.2 GO:0097232 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
8.0 16.0 GO:0035577 azurophil granule membrane(GO:0035577)
8.0 48.0 GO:0005610 laminin-5 complex(GO:0005610)
8.0 103.6 GO:0031143 pseudopodium(GO:0031143)
7.9 7.9 GO:0005588 collagen type V trimer(GO:0005588)
7.7 77.4 GO:0045179 apical cortex(GO:0045179)
7.6 30.5 GO:0071914 prominosome(GO:0071914)
7.6 251.7 GO:0030131 clathrin adaptor complex(GO:0030131)
7.4 154.7 GO:0031528 microvillus membrane(GO:0031528)
7.2 50.5 GO:0097136 Bcl-2 family protein complex(GO:0097136)
7.1 21.3 GO:0005656 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
7.1 7.1 GO:0031094 platelet dense tubular network(GO:0031094)
7.0 48.7 GO:0001651 dense fibrillar component(GO:0001651)
6.5 124.2 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
6.5 516.3 GO:0031526 brush border membrane(GO:0031526)
6.4 12.8 GO:0032010 phagolysosome(GO:0032010)
6.3 50.3 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
6.2 61.8 GO:0032437 cuticular plate(GO:0032437)
6.0 23.9 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
5.6 39.5 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
5.6 22.3 GO:0097513 myosin II filament(GO:0097513)
5.5 38.8 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
5.5 10.9 GO:0070821 tertiary granule membrane(GO:0070821)
5.4 21.8 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
5.2 41.8 GO:0097208 alveolar lamellar body(GO:0097208)
5.2 20.8 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
5.1 633.0 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
4.9 14.7 GO:0019815 B cell receptor complex(GO:0019815)
4.8 38.5 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
4.8 33.4 GO:0036449 microtubule minus-end(GO:0036449)
4.8 62.0 GO:0032591 dendritic spine membrane(GO:0032591)
4.7 56.8 GO:0032433 filopodium tip(GO:0032433)
4.7 37.7 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
4.6 129.5 GO:0008305 integrin complex(GO:0008305)
4.6 156.7 GO:0016328 lateral plasma membrane(GO:0016328)
4.6 22.8 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
4.5 13.6 GO:0005594 collagen type IX trimer(GO:0005594)
4.5 4.5 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
4.5 120.7 GO:0001772 immunological synapse(GO:0001772)
4.4 65.3 GO:0042613 MHC class II protein complex(GO:0042613)
4.2 33.5 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
4.0 20.2 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
4.0 20.1 GO:0031904 endosome lumen(GO:0031904)
4.0 7.9 GO:0031095 platelet dense tubular network membrane(GO:0031095)
4.0 106.7 GO:0001533 cornified envelope(GO:0001533)
3.9 3.9 GO:0005593 FACIT collagen trimer(GO:0005593)
3.6 3.6 GO:0098651 basement membrane collagen trimer(GO:0098651)
3.5 297.1 GO:0032587 ruffle membrane(GO:0032587)
3.5 7.0 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
3.5 83.3 GO:0034706 sodium channel complex(GO:0034706)
3.4 24.1 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
3.3 16.3 GO:0097524 sperm plasma membrane(GO:0097524)
3.2 19.0 GO:0097342 ripoptosome(GO:0097342)
3.2 217.8 GO:0045095 keratin filament(GO:0045095)
3.1 24.8 GO:0097443 sorting endosome(GO:0097443)
3.1 12.4 GO:0033269 internode region of axon(GO:0033269)
3.0 6.1 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
3.0 74.8 GO:0042629 mast cell granule(GO:0042629)
3.0 17.7 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
2.9 5.8 GO:0045098 type III intermediate filament(GO:0045098)
2.9 5.8 GO:0031166 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
2.9 11.6 GO:0097451 glial limiting end-foot(GO:0097451)
2.9 8.7 GO:0042642 actomyosin, myosin complex part(GO:0042642)
2.8 2.8 GO:0044393 microspike(GO:0044393)
2.8 8.3 GO:0005896 interleukin-6 receptor complex(GO:0005896) ciliary neurotrophic factor receptor complex(GO:0070110)
2.7 19.2 GO:0090543 Flemming body(GO:0090543)
2.7 8.1 GO:0060091 kinocilium(GO:0060091)
2.6 13.2 GO:0000836 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
2.6 7.8 GO:0031230 intrinsic component of cell outer membrane(GO:0031230) integral component of cell outer membrane(GO:0045203)
2.6 15.4 GO:0032444 activin responsive factor complex(GO:0032444)
2.6 35.9 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
2.5 27.7 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
2.5 110.5 GO:0055038 recycling endosome membrane(GO:0055038)
2.5 9.9 GO:0032059 bleb(GO:0032059)
2.5 9.8 GO:0031088 platelet dense granule membrane(GO:0031088)
2.5 7.4 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
2.4 85.7 GO:0044295 axonal growth cone(GO:0044295)
2.4 138.3 GO:0034707 chloride channel complex(GO:0034707)
2.4 33.8 GO:0030670 phagocytic vesicle membrane(GO:0030670)
2.4 38.3 GO:0001891 phagocytic cup(GO:0001891)
2.4 19.1 GO:0070578 RISC-loading complex(GO:0070578)
2.3 11.6 GO:0042581 specific granule(GO:0042581)
2.3 16.2 GO:0000788 nuclear nucleosome(GO:0000788)
2.3 4.6 GO:0000306 extrinsic component of vacuolar membrane(GO:0000306)
2.3 9.2 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
2.3 41.2 GO:0005614 interstitial matrix(GO:0005614)
2.3 20.5 GO:0044327 dendritic spine head(GO:0044327)
2.3 6.8 GO:0035355 Toll-like receptor 2-Toll-like receptor 6 protein complex(GO:0035355)
2.3 27.2 GO:0001939 female pronucleus(GO:0001939)
2.2 123.3 GO:0031901 early endosome membrane(GO:0031901)
2.2 22.3 GO:0032588 trans-Golgi network membrane(GO:0032588)
2.2 49.0 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
2.2 13.2 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
2.2 24.1 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
2.2 571.9 GO:0009897 external side of plasma membrane(GO:0009897)
2.1 6.4 GO:1990769 proximal neuron projection(GO:1990769)
2.1 430.6 GO:0016323 basolateral plasma membrane(GO:0016323)
2.1 4.3 GO:0097427 microtubule bundle(GO:0097427)
2.1 2.1 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
2.1 138.7 GO:0032580 Golgi cisterna membrane(GO:0032580)
2.1 14.9 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
2.1 14.8 GO:0005579 membrane attack complex(GO:0005579)
2.1 12.7 GO:0042584 chromaffin granule membrane(GO:0042584)
2.1 25.0 GO:0044232 organelle membrane contact site(GO:0044232)
2.1 20.8 GO:1990635 proximal dendrite(GO:1990635)
2.1 10.3 GO:0031091 platelet alpha granule(GO:0031091)
2.0 4.1 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
2.0 8.2 GO:0033093 Weibel-Palade body(GO:0033093)
2.0 53.8 GO:0045335 phagocytic vesicle(GO:0045335)
1.9 9.7 GO:0071953 elastic fiber(GO:0071953)
1.9 15.4 GO:0033263 CORVET complex(GO:0033263)
1.9 15.4 GO:0031209 SCAR complex(GO:0031209)
1.9 45.9 GO:0031225 anchored component of membrane(GO:0031225)
1.9 9.6 GO:0070695 FHF complex(GO:0070695)
1.9 9.3 GO:1990716 axonemal central apparatus(GO:1990716)
1.8 5.5 GO:1990032 parallel fiber(GO:1990032)
1.8 11.1 GO:0005785 signal recognition particle receptor complex(GO:0005785)
1.8 1.8 GO:0001740 Barr body(GO:0001740)
1.8 439.9 GO:0045177 apical part of cell(GO:0045177)
1.8 16.3 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
1.8 34.1 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
1.8 12.5 GO:0042599 lamellar body(GO:0042599)
1.8 40.8 GO:0046658 anchored component of plasma membrane(GO:0046658)
1.8 8.8 GO:1990130 Iml1 complex(GO:1990130)
1.7 5.2 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
1.7 8.7 GO:0044530 supraspliceosomal complex(GO:0044530)
1.7 3.5 GO:0005818 astral microtubule(GO:0000235) aster(GO:0005818)
1.7 112.1 GO:0005871 kinesin complex(GO:0005871)
1.7 201.5 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
1.7 10.2 GO:0042825 MHC class I peptide loading complex(GO:0042824) TAP complex(GO:0042825)
1.7 3.3 GO:0005839 proteasome core complex(GO:0005839)
1.6 4.8 GO:0044224 juxtaparanode region of axon(GO:0044224)
1.6 85.1 GO:0048475 membrane coat(GO:0030117) coated membrane(GO:0048475)
1.6 6.4 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
1.6 25.4 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
1.6 4.8 GO:0071942 XPC complex(GO:0071942)
1.6 6.3 GO:0048476 Holliday junction resolvase complex(GO:0048476)
1.6 17.4 GO:0042612 MHC class I protein complex(GO:0042612)
1.6 4.7 GO:0033557 Slx1-Slx4 complex(GO:0033557)
1.6 11.0 GO:0030057 desmosome(GO:0030057)
1.5 4.6 GO:0071149 TEAD-2-YAP complex(GO:0071149)
1.5 50.8 GO:0005791 rough endoplasmic reticulum(GO:0005791)
1.5 3.0 GO:0036398 TCR signalosome(GO:0036398)
1.5 8.9 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
1.5 8.8 GO:0043020 NADPH oxidase complex(GO:0043020)
1.5 4.4 GO:0071001 U4/U6 snRNP(GO:0071001)
1.4 4.3 GO:0005940 septin ring(GO:0005940)
1.4 27.9 GO:0035098 ESC/E(Z) complex(GO:0035098)
1.4 4.1 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
1.3 6.7 GO:0032389 MutLalpha complex(GO:0032389)
1.3 14.8 GO:0036038 MKS complex(GO:0036038)
1.3 7.9 GO:1990111 spermatoproteasome complex(GO:1990111)
1.3 1.3 GO:0044299 C-fiber(GO:0044299)
1.3 26.2 GO:0046930 pore complex(GO:0046930)
1.3 443.1 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
1.3 9.2 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
1.3 2.5 GO:0044317 rod spherule(GO:0044317)
1.3 2.5 GO:0033588 Elongator holoenzyme complex(GO:0033588)
1.2 14.5 GO:0061702 inflammasome complex(GO:0061702)
1.2 2624.4 GO:0070062 extracellular exosome(GO:0070062)
1.2 3.6 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
1.2 2.4 GO:0031933 telomeric heterochromatin(GO:0031933)
1.2 5.8 GO:0035189 Rb-E2F complex(GO:0035189)
1.1 2.3 GO:0001674 female germ cell nucleus(GO:0001674)
1.1 14.7 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
1.1 13.5 GO:0000124 SAGA complex(GO:0000124)
1.1 49.9 GO:0072686 mitotic spindle(GO:0072686)
1.1 4.4 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
1.1 5.5 GO:0030136 clathrin-coated vesicle(GO:0030136)
1.1 190.3 GO:0005925 focal adhesion(GO:0005925)
1.1 28.5 GO:0060170 ciliary membrane(GO:0060170)
1.1 10.8 GO:0005721 pericentric heterochromatin(GO:0005721)
1.1 43.1 GO:0005604 basement membrane(GO:0005604)
1.1 18.0 GO:0005795 Golgi stack(GO:0005795)
1.0 4.2 GO:0032021 NELF complex(GO:0032021)
1.0 5.2 GO:1903768 sweet taste receptor complex(GO:1903767) taste receptor complex(GO:1903768)
1.0 1.0 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
1.0 9.3 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
1.0 4.1 GO:0042589 zymogen granule membrane(GO:0042589)
1.0 34.6 GO:0005720 nuclear heterochromatin(GO:0005720)
1.0 35.6 GO:0001726 ruffle(GO:0001726)
1.0 21.7 GO:0005902 microvillus(GO:0005902)
1.0 9.8 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
1.0 6.9 GO:0031616 spindle pole centrosome(GO:0031616)
1.0 10.7 GO:0008278 cohesin complex(GO:0008278)
1.0 2.9 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
1.0 12.6 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
1.0 6.7 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
1.0 4.8 GO:0005796 Golgi lumen(GO:0005796)
0.9 90.0 GO:0016605 PML body(GO:0016605)
0.9 9.4 GO:0035102 PRC1 complex(GO:0035102)
0.9 10.3 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.9 196.6 GO:0000139 Golgi membrane(GO:0000139)
0.9 1.8 GO:0034457 Mpp10 complex(GO:0034457)
0.9 6.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.9 3.5 GO:0043159 acrosomal matrix(GO:0043159)
0.9 2.6 GO:0005846 nuclear cap binding complex(GO:0005846)
0.9 3.4 GO:0035859 Seh1-associated complex(GO:0035859)
0.9 4.3 GO:0031262 Ndc80 complex(GO:0031262)
0.8 7.6 GO:0072687 meiotic spindle(GO:0072687)
0.8 1.6 GO:0005828 kinetochore microtubule(GO:0005828)
0.8 1.6 GO:0043293 apoptosome(GO:0043293)
0.8 8.1 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.8 31.8 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.8 7.0 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.8 4.6 GO:0005883 neurofilament(GO:0005883)
0.8 9.2 GO:0032809 neuronal cell body membrane(GO:0032809)
0.8 6.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.8 13.1 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.7 79.9 GO:0001650 fibrillar center(GO:0001650)
0.7 6.3 GO:0090576 RNA polymerase III transcription factor complex(GO:0090576)
0.7 2.0 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.7 2.7 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.7 2.0 GO:0044609 DBIRD complex(GO:0044609)
0.7 2.0 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.7 329.1 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.6 1.2 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.6 10.5 GO:0000145 exocyst(GO:0000145)
0.6 10.3 GO:0034451 centriolar satellite(GO:0034451)
0.6 2.3 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.6 3.5 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.6 2.9 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.6 4.0 GO:0005677 chromatin silencing complex(GO:0005677)
0.6 22.0 GO:0008023 transcription elongation factor complex(GO:0008023)
0.6 54.0 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.6 5.5 GO:0042555 MCM complex(GO:0042555)
0.5 1.6 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.5 7.1 GO:0005905 clathrin-coated pit(GO:0005905)
0.5 1.6 GO:1990745 EARP complex(GO:1990745)
0.5 1.1 GO:0031436 BRCA1-BARD1 complex(GO:0031436)
0.5 0.5 GO:0044316 cone cell pedicle(GO:0044316)
0.5 39.8 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.5 4.0 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.5 31.7 GO:0016363 nuclear matrix(GO:0016363)
0.5 31.6 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.5 2.5 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.5 2.9 GO:0005640 nuclear outer membrane(GO:0005640)
0.5 25.3 GO:0031252 cell leading edge(GO:0031252)
0.5 7.6 GO:0005776 autophagosome(GO:0005776)
0.5 1.9 GO:0000974 Prp19 complex(GO:0000974)
0.5 1.4 GO:0034399 nuclear periphery(GO:0034399)
0.5 0.9 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.5 0.9 GO:0071782 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.5 1.9 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371) HULC complex(GO:0033503)
0.5 6.8 GO:0035145 exon-exon junction complex(GO:0035145)
0.5 1.8 GO:0036156 inner dynein arm(GO:0036156)
0.4 3.1 GO:0030991 intraciliary transport particle A(GO:0030991)
0.4 7.5 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.4 2.7 GO:0000796 condensin complex(GO:0000796)
0.4 4.8 GO:0071004 U2-type prespliceosome(GO:0071004)
0.4 14.3 GO:0005657 replication fork(GO:0005657)
0.4 6.3 GO:0035861 site of double-strand break(GO:0035861)
0.4 2.3 GO:0032590 dendrite membrane(GO:0032590)
0.4 8.3 GO:0005921 gap junction(GO:0005921)
0.4 1.8 GO:0042587 glycogen granule(GO:0042587)
0.4 4.6 GO:0032420 stereocilium(GO:0032420)
0.4 0.7 GO:0033647 host intracellular organelle(GO:0033647) host intracellular membrane-bounded organelle(GO:0033648)
0.3 0.3 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.3 1.4 GO:0035976 AP1 complex(GO:0035976)
0.3 0.7 GO:0033186 CAF-1 complex(GO:0033186)
0.3 2.4 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.3 3.0 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.3 3.2 GO:0030014 CCR4-NOT complex(GO:0030014)
0.3 3.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.3 22.9 GO:0005769 early endosome(GO:0005769)
0.3 66.6 GO:0009986 cell surface(GO:0009986)
0.3 1.9 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.3 5.4 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.3 6.9 GO:0055037 recycling endosome(GO:0055037)
0.3 2.1 GO:0044292 dendrite terminus(GO:0044292)
0.3 1.8 GO:1990246 uniplex complex(GO:1990246)
0.3 1.4 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.3 2.3 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.3 10.1 GO:0044452 nucleolar part(GO:0044452)
0.2 2.2 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.2 1.5 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.2 7.5 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.2 3.8 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.2 0.9 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.2 1.8 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.2 0.7 GO:0032301 MutSalpha complex(GO:0032301)
0.2 3.0 GO:0019013 viral nucleocapsid(GO:0019013)
0.2 1.7 GO:0097542 ciliary tip(GO:0097542)
0.2 31.1 GO:0031965 nuclear membrane(GO:0031965)
0.2 0.2 GO:0042627 chylomicron(GO:0042627)
0.2 2.7 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.2 2.3 GO:0032040 small-subunit processome(GO:0032040)
0.2 5.8 GO:0005802 trans-Golgi network(GO:0005802)
0.2 2.7 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.2 2.3 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.2 2.1 GO:1904115 axon cytoplasm(GO:1904115)
0.2 1.2 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.2 8.5 GO:0019898 extrinsic component of membrane(GO:0019898)
0.2 1.6 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.1 29.0 GO:0000790 nuclear chromatin(GO:0000790)
0.1 0.5 GO:0043083 synaptic cleft(GO:0043083)
0.1 3.0 GO:0005882 intermediate filament(GO:0005882)
0.1 0.9 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.1 0.7 GO:0000800 lateral element(GO:0000800)
0.1 2.3 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.1 0.2 GO:0055087 Ski complex(GO:0055087)
0.1 0.4 GO:0030008 TRAPP complex(GO:0030008)
0.1 229.8 GO:0016021 integral component of membrane(GO:0016021)
0.0 1.7 GO:0016592 mediator complex(GO:0016592)
0.0 0.1 GO:0000780 condensed nuclear chromosome, centromeric region(GO:0000780)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
48.3 144.9 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
27.0 324.6 GO:0019911 structural constituent of myelin sheath(GO:0019911)
24.4 73.2 GO:0042284 sphingolipid delta-4 desaturase activity(GO:0042284)
23.2 208.4 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
20.2 101.0 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
20.2 80.7 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
19.1 57.2 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
18.8 93.9 GO:1990254 keratin filament binding(GO:1990254)
18.2 109.0 GO:0005499 vitamin D binding(GO:0005499)
17.6 70.5 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
15.4 184.4 GO:0015245 fatty acid transporter activity(GO:0015245)
14.4 43.3 GO:0070573 metallodipeptidase activity(GO:0070573)
13.8 68.8 GO:0050785 advanced glycation end-product receptor activity(GO:0050785)
13.4 40.2 GO:0038100 nodal binding(GO:0038100)
13.1 39.3 GO:0034040 lipid-transporting ATPase activity(GO:0034040) sterol-transporting ATPase activity(GO:0034041) glycoprotein transporter activity(GO:0034437)
12.6 37.9 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
12.5 74.8 GO:0051434 BH3 domain binding(GO:0051434)
12.3 209.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
12.2 48.6 GO:0035727 lysophosphatidic acid binding(GO:0035727)
12.0 36.1 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
11.3 56.4 GO:0030348 syntaxin-3 binding(GO:0030348)
11.2 33.7 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
11.1 33.2 GO:0004657 proline dehydrogenase activity(GO:0004657)
10.9 32.8 GO:0002060 purine nucleobase binding(GO:0002060)
10.8 43.1 GO:0004967 glucagon receptor activity(GO:0004967)
10.8 161.4 GO:0045295 gamma-catenin binding(GO:0045295)
10.7 32.2 GO:0015389 pyrimidine- and adenine-specific:sodium symporter activity(GO:0015389)
10.7 117.2 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
10.6 42.4 GO:0008265 Mo-molybdopterin cofactor sulfurase activity(GO:0008265)
10.4 52.1 GO:0038132 neuregulin binding(GO:0038132)
10.2 40.6 GO:0047276 N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
10.1 60.8 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
10.0 29.9 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
9.9 29.7 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
9.9 39.5 GO:0035827 rubidium ion transmembrane transporter activity(GO:0035827)
9.6 38.4 GO:0051870 methotrexate binding(GO:0051870)
9.4 46.8 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
9.3 37.0 GO:0045159 myosin II binding(GO:0045159)
9.2 27.5 GO:0019763 immunoglobulin receptor activity(GO:0019763)
9.1 81.9 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
9.0 27.1 GO:0050294 steroid sulfotransferase activity(GO:0050294)
8.5 68.0 GO:0008172 S-methyltransferase activity(GO:0008172)
8.5 50.8 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
8.4 67.5 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
8.4 16.8 GO:0031711 bradykinin receptor binding(GO:0031711)
8.1 24.4 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
8.0 56.3 GO:0004957 prostaglandin E receptor activity(GO:0004957)
7.9 79.3 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
7.9 31.7 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
7.9 110.6 GO:0042609 CD4 receptor binding(GO:0042609)
7.8 38.8 GO:0004920 interleukin-10 receptor activity(GO:0004920)
7.7 69.6 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
7.7 38.4 GO:0043682 copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682)
7.7 23.0 GO:0016403 dimethylargininase activity(GO:0016403)
7.6 68.1 GO:0042285 xylosyltransferase activity(GO:0042285)
7.3 22.0 GO:0015563 thiamine transmembrane transporter activity(GO:0015234) uptake transmembrane transporter activity(GO:0015563)
7.1 21.2 GO:0098603 selenol Se-methyltransferase activity(GO:0098603)
7.0 35.2 GO:0070051 fibrinogen binding(GO:0070051)
7.0 21.0 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263)
7.0 70.1 GO:0004385 guanylate kinase activity(GO:0004385)
7.0 28.0 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
7.0 97.7 GO:0005243 gap junction channel activity(GO:0005243)
7.0 48.8 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
7.0 146.0 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
6.9 20.7 GO:0009384 N-acylmannosamine kinase activity(GO:0009384)
6.8 34.1 GO:0052813 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
6.8 81.2 GO:0016208 AMP binding(GO:0016208)
6.7 20.2 GO:0004566 beta-glucuronidase activity(GO:0004566)
6.7 93.8 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
6.7 40.2 GO:0019767 IgE receptor activity(GO:0019767)
6.7 20.0 GO:0042895 antibiotic transporter activity(GO:0042895)
6.6 19.8 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
6.5 45.8 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
6.4 141.8 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
6.3 37.9 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)
6.3 18.9 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
6.2 18.7 GO:0004911 interleukin-2 receptor activity(GO:0004911)
6.2 6.2 GO:0090555 phosphatidylethanolamine-translocating ATPase activity(GO:0090555)
6.0 17.9 GO:0015141 succinate transmembrane transporter activity(GO:0015141)
5.8 17.5 GO:0003941 L-serine ammonia-lyase activity(GO:0003941)
5.8 23.3 GO:0015350 methotrexate transporter activity(GO:0015350)
5.8 40.8 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661)
5.8 69.4 GO:0070008 serine-type exopeptidase activity(GO:0070008)
5.8 17.3 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797)
5.7 40.1 GO:1990430 extracellular matrix protein binding(GO:1990430)
5.6 22.5 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
5.6 16.9 GO:1902379 chemoattractant activity involved in axon guidance(GO:1902379)
5.6 22.5 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
5.6 22.4 GO:0031750 D3 dopamine receptor binding(GO:0031750)
5.6 16.7 GO:0031714 C5a anaphylatoxin chemotactic receptor binding(GO:0031714)
5.5 11.0 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
5.5 65.9 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
5.5 43.6 GO:0045545 syndecan binding(GO:0045545)
5.4 21.8 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
5.4 59.9 GO:0019864 IgG binding(GO:0019864)
5.4 10.8 GO:0015137 citrate transmembrane transporter activity(GO:0015137)
5.3 42.6 GO:0008430 selenium binding(GO:0008430)
5.3 15.9 GO:0050429 calcium-dependent phospholipase C activity(GO:0050429)
5.2 26.2 GO:0042608 T cell receptor binding(GO:0042608)
5.2 26.0 GO:0070401 NADP+ binding(GO:0070401)
5.2 15.5 GO:0051380 norepinephrine binding(GO:0051380)
5.1 25.7 GO:0022841 potassium ion leak channel activity(GO:0022841)
5.1 46.3 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
5.1 51.5 GO:0019957 C-C chemokine binding(GO:0019957)
5.1 10.2 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
5.0 95.6 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
5.0 20.1 GO:0002054 nucleobase binding(GO:0002054)
5.0 119.8 GO:0031489 myosin V binding(GO:0031489)
5.0 19.9 GO:0043120 tumor necrosis factor binding(GO:0043120)
5.0 9.9 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
5.0 14.9 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
4.9 4.9 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
4.9 29.3 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
4.9 43.9 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
4.9 14.6 GO:0004528 phosphodiesterase I activity(GO:0004528)
4.9 14.6 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
4.8 86.7 GO:0005522 profilin binding(GO:0005522)
4.8 52.5 GO:0005000 vasopressin receptor activity(GO:0005000)
4.8 14.3 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
4.8 19.0 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
4.7 28.5 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
4.7 94.3 GO:0004602 glutathione peroxidase activity(GO:0004602)
4.6 22.9 GO:0042289 MHC class II protein binding(GO:0042289)
4.6 13.7 GO:0015252 hydrogen ion channel activity(GO:0015252)
4.5 63.3 GO:0033691 sialic acid binding(GO:0033691)
4.5 18.1 GO:0017089 glycolipid transporter activity(GO:0017089)
4.5 58.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
4.5 8.9 GO:0003872 6-phosphofructokinase activity(GO:0003872)
4.5 22.4 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
4.4 13.3 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
4.4 17.7 GO:0010465 nerve growth factor receptor activity(GO:0010465)
4.4 4.4 GO:0019862 IgA binding(GO:0019862)
4.4 4.4 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
4.4 13.2 GO:0038181 bile acid receptor activity(GO:0038181)
4.4 48.2 GO:0070700 BMP receptor binding(GO:0070700)
4.4 43.6 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
4.4 13.1 GO:0072590 N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590)
4.4 17.4 GO:0004771 sterol esterase activity(GO:0004771)
4.3 13.0 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
4.3 8.5 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
4.2 12.6 GO:0070061 fructose binding(GO:0070061)
4.2 492.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
4.2 12.6 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
4.1 16.6 GO:0050998 nitric-oxide synthase binding(GO:0050998)
4.1 12.4 GO:1990460 leptin receptor binding(GO:1990460)
4.1 28.8 GO:0004111 creatine kinase activity(GO:0004111)
4.1 20.3 GO:0046923 ER retention sequence binding(GO:0046923)
4.0 16.1 GO:0047619 acylcarnitine hydrolase activity(GO:0047619)
4.0 20.0 GO:0070513 death domain binding(GO:0070513)
4.0 35.9 GO:0034987 immunoglobulin receptor binding(GO:0034987)
4.0 11.9 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
4.0 119.2 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
3.9 19.7 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
3.9 82.6 GO:0001530 lipopolysaccharide binding(GO:0001530)
3.9 31.4 GO:0030368 interleukin-17 receptor activity(GO:0030368)
3.9 11.7 GO:0070735 protein-glycine ligase activity(GO:0070735)
3.9 69.9 GO:0017081 chloride channel regulator activity(GO:0017081)
3.9 15.5 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
3.9 11.6 GO:0032810 sterol response element binding(GO:0032810)
3.9 30.8 GO:0004035 alkaline phosphatase activity(GO:0004035)
3.8 34.6 GO:0001013 RNA polymerase I regulatory region DNA binding(GO:0001013)
3.8 15.4 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
3.8 11.5 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
3.8 15.3 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
3.8 26.6 GO:0015651 quaternary ammonium group transmembrane transporter activity(GO:0015651)
3.7 11.1 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
3.7 29.5 GO:0008046 axon guidance receptor activity(GO:0008046)
3.7 18.3 GO:0097001 ceramide binding(GO:0097001)
3.6 29.2 GO:0050544 icosatetraenoic acid binding(GO:0050543) arachidonic acid binding(GO:0050544)
3.6 36.5 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
3.6 10.9 GO:0004040 amidase activity(GO:0004040)
3.6 14.5 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
3.6 10.8 GO:0004918 interleukin-8 receptor activity(GO:0004918) interleukin-8 binding(GO:0019959)
3.6 18.0 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
3.6 10.8 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
3.6 64.7 GO:0015106 bicarbonate transmembrane transporter activity(GO:0015106)
3.6 35.8 GO:0005412 glucose:sodium symporter activity(GO:0005412)
3.5 35.5 GO:0051959 dynein light intermediate chain binding(GO:0051959)
3.5 91.6 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
3.5 31.3 GO:0046790 virion binding(GO:0046790)
3.4 13.8 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
3.4 20.5 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
3.4 13.6 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
3.4 10.2 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
3.4 10.2 GO:0001605 adrenomedullin receptor activity(GO:0001605)
3.3 70.3 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
3.3 16.6 GO:0034235 GPI anchor binding(GO:0034235)
3.3 165.4 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
3.2 13.0 GO:0097108 hedgehog family protein binding(GO:0097108)
3.2 9.7 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
3.2 9.7 GO:0046624 sphingolipid transporter activity(GO:0046624)
3.2 35.2 GO:0030346 protein phosphatase 2B binding(GO:0030346)
3.2 6.4 GO:0070053 thrombospondin receptor activity(GO:0070053)
3.2 86.2 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
3.2 12.7 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
3.2 6.3 GO:0004027 alcohol sulfotransferase activity(GO:0004027)
3.1 9.3 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
3.1 102.0 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
3.1 15.4 GO:0004994 somatostatin receptor activity(GO:0004994)
3.0 18.0 GO:0016493 C-C chemokine receptor activity(GO:0016493)
3.0 50.2 GO:0004697 protein kinase C activity(GO:0004697)
2.9 14.4 GO:0004908 interleukin-1 receptor activity(GO:0004908)
2.9 11.5 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
2.9 25.8 GO:0042577 lipid phosphatase activity(GO:0042577)
2.9 45.8 GO:0031996 thioesterase binding(GO:0031996)
2.9 14.3 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
2.8 22.7 GO:0030249 guanylate cyclase regulator activity(GO:0030249)
2.8 11.3 GO:0019956 chemokine binding(GO:0019956)
2.8 47.8 GO:0015643 toxic substance binding(GO:0015643)
2.8 8.4 GO:0019958 C-X-C chemokine binding(GO:0019958)
2.8 25.1 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
2.8 11.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
2.8 49.5 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
2.7 32.8 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
2.7 2.7 GO:0001637 G-protein coupled chemoattractant receptor activity(GO:0001637)
2.7 8.2 GO:0070300 phosphatidic acid binding(GO:0070300)
2.7 21.7 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
2.7 24.4 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
2.6 7.9 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
2.6 185.0 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
2.6 33.6 GO:0097200 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153) cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
2.6 36.1 GO:0070411 I-SMAD binding(GO:0070411)
2.6 25.8 GO:0032036 myosin heavy chain binding(GO:0032036)
2.6 30.6 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
2.5 71.0 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701)
2.5 15.1 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
2.5 67.9 GO:0016849 cyclase activity(GO:0009975) phosphorus-oxygen lyase activity(GO:0016849)
2.5 7.5 GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315)
2.5 89.8 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
2.5 10.0 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
2.5 22.2 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
2.5 27.1 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451)
2.5 4.9 GO:0015265 urea channel activity(GO:0015265)
2.5 9.8 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
2.5 7.4 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
2.4 7.3 GO:0015220 choline transmembrane transporter activity(GO:0015220)
2.4 2.4 GO:0097603 temperature-gated ion channel activity(GO:0097603)
2.4 9.7 GO:0019776 Atg8 ligase activity(GO:0019776)
2.4 7.2 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
2.4 26.5 GO:0051011 microtubule minus-end binding(GO:0051011)
2.4 14.4 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
2.4 55.0 GO:0001968 fibronectin binding(GO:0001968)
2.4 7.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
2.4 9.5 GO:0004949 cannabinoid receptor activity(GO:0004949)
2.4 26.1 GO:0008131 primary amine oxidase activity(GO:0008131)
2.4 11.8 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
2.4 14.2 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
2.4 4.7 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
2.4 14.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
2.3 14.0 GO:0032554 purine deoxyribonucleotide binding(GO:0032554)
2.3 111.3 GO:0005044 scavenger receptor activity(GO:0005044)
2.3 27.5 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
2.3 11.4 GO:0018812 3-hydroxyacyl-CoA dehydratase activity(GO:0018812)
2.3 32.0 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
2.3 16.0 GO:0052742 phosphatidylinositol kinase activity(GO:0052742)
2.3 6.9 GO:0015204 urea transmembrane transporter activity(GO:0015204)
2.3 6.8 GO:0004769 steroid delta-isomerase activity(GO:0004769)
2.3 6.8 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
2.3 47.4 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
2.2 9.0 GO:0004945 angiotensin type II receptor activity(GO:0004945)
2.2 17.9 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
2.2 11.2 GO:0050694 galactose 3-O-sulfotransferase activity(GO:0050694)
2.2 13.4 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
2.2 13.3 GO:0046979 TAP binding(GO:0046977) TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
2.2 28.9 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
2.2 31.1 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
2.2 6.6 GO:0019809 spermidine binding(GO:0019809)
2.2 13.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
2.2 19.8 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
2.2 15.4 GO:0070097 delta-catenin binding(GO:0070097)
2.2 6.6 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
2.2 13.2 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
2.2 11.0 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
2.2 11.0 GO:1990932 5.8S rRNA binding(GO:1990932)
2.2 6.5 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
2.2 106.4 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
2.2 8.6 GO:0045125 bioactive lipid receptor activity(GO:0045125)
2.2 12.9 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
2.1 8.6 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
2.1 15.0 GO:0019808 polyamine binding(GO:0019808)
2.1 47.0 GO:0005452 inorganic anion exchanger activity(GO:0005452)
2.1 8.5 GO:0034452 dynactin binding(GO:0034452)
2.1 6.4 GO:0004793 threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732) serine binding(GO:0070905)
2.1 8.5 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
2.1 8.4 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
2.1 6.3 GO:0004655 porphobilinogen synthase activity(GO:0004655)
2.1 8.3 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
2.1 18.7 GO:0001727 lipid kinase activity(GO:0001727)
2.1 6.2 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
2.1 43.6 GO:0042169 SH2 domain binding(GO:0042169)
2.1 10.4 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
2.1 10.3 GO:0030955 potassium ion binding(GO:0030955)
2.1 8.2 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
2.1 16.4 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
2.0 8.2 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
2.0 10.2 GO:0031404 chloride ion binding(GO:0031404)
2.0 12.2 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
2.0 36.4 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
2.0 28.3 GO:0003688 DNA replication origin binding(GO:0003688)
2.0 16.0 GO:0031681 G-protein beta-subunit binding(GO:0031681)
2.0 14.0 GO:0004630 phospholipase D activity(GO:0004630)
2.0 39.9 GO:0030742 GTP-dependent protein binding(GO:0030742)
2.0 61.7 GO:0042605 peptide antigen binding(GO:0042605)
2.0 4.0 GO:0030977 taurine binding(GO:0030977)
2.0 25.6 GO:0047372 acylglycerol lipase activity(GO:0047372)
2.0 3.9 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
2.0 3.9 GO:0008158 hedgehog receptor activity(GO:0008158)
2.0 9.8 GO:0033142 progesterone receptor binding(GO:0033142)
2.0 5.9 GO:0001565 phorbol ester receptor activity(GO:0001565)
1.9 9.7 GO:0004969 histamine receptor activity(GO:0004969)
1.9 92.8 GO:0004896 cytokine receptor activity(GO:0004896)
1.9 9.6 GO:0098918 structural constituent of synapse(GO:0098918)
1.9 140.6 GO:0005178 integrin binding(GO:0005178)
1.9 3.8 GO:0051022 Rho GDP-dissociation inhibitor binding(GO:0051022)
1.9 24.7 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
1.9 7.6 GO:0000293 ferric-chelate reductase activity(GO:0000293)
1.9 235.6 GO:0008201 heparin binding(GO:0008201)
1.9 5.6 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
1.9 20.5 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
1.9 33.3 GO:0033613 activating transcription factor binding(GO:0033613)
1.8 5.5 GO:0017168 5-oxoprolinase (ATP-hydrolyzing) activity(GO:0017168)
1.8 7.3 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
1.8 9.1 GO:0001758 retinal dehydrogenase activity(GO:0001758)
1.8 12.7 GO:0051861 glycolipid binding(GO:0051861)
1.8 3.6 GO:0000253 3-keto sterol reductase activity(GO:0000253)
1.8 52.3 GO:0005504 fatty acid binding(GO:0005504)
1.8 5.4 GO:0009041 uridylate kinase activity(GO:0009041)
1.8 7.1 GO:0004301 epoxide hydrolase activity(GO:0004301)
1.8 5.3 GO:1990715 mRNA CDS binding(GO:1990715)
1.8 21.2 GO:0008097 5S rRNA binding(GO:0008097)
1.8 5.3 GO:0001069 regulatory region RNA binding(GO:0001069)
1.8 185.8 GO:0017124 SH3 domain binding(GO:0017124)
1.8 7.0 GO:0001093 TFIIB-class transcription factor binding(GO:0001093)
1.7 10.5 GO:0051880 G-quadruplex DNA binding(GO:0051880)
1.7 26.2 GO:0070412 R-SMAD binding(GO:0070412)
1.7 13.8 GO:0051525 NFAT protein binding(GO:0051525)
1.7 10.4 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
1.7 34.1 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
1.7 3.4 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
1.7 1.7 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
1.7 13.5 GO:0023026 MHC class II protein complex binding(GO:0023026)
1.7 8.4 GO:0015166 polyol transmembrane transporter activity(GO:0015166) glycerol transmembrane transporter activity(GO:0015168)
1.7 24.8 GO:0043522 leucine zipper domain binding(GO:0043522)
1.6 4.9 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
1.6 13.1 GO:0042043 neurexin family protein binding(GO:0042043)
1.6 21.1 GO:0033130 acetylcholine receptor binding(GO:0033130)
1.6 4.9 GO:0030626 U12 snRNA binding(GO:0030626)
1.6 25.9 GO:0048020 CCR chemokine receptor binding(GO:0048020)
1.6 33.8 GO:0015923 mannosidase activity(GO:0015923)
1.6 19.3 GO:0003708 retinoic acid receptor activity(GO:0003708)
1.6 35.3 GO:0017075 syntaxin-1 binding(GO:0017075)
1.6 30.4 GO:0008199 ferric iron binding(GO:0008199)
1.6 17.6 GO:0008242 omega peptidase activity(GO:0008242)
1.6 570.4 GO:0050839 cell adhesion molecule binding(GO:0050839)
1.6 4.7 GO:0004359 glutaminase activity(GO:0004359)
1.6 12.6 GO:0015299 solute:proton antiporter activity(GO:0015299)
1.6 11.1 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
1.6 9.3 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
1.6 6.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
1.5 1.5 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
1.5 29.2 GO:0017056 structural constituent of nuclear pore(GO:0017056)
1.5 13.8 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
1.5 4.6 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
1.5 12.1 GO:0035033 histone deacetylase regulator activity(GO:0035033)
1.5 7.6 GO:0004064 arylesterase activity(GO:0004064)
1.5 4.5 GO:0015292 uniporter activity(GO:0015292)
1.5 16.6 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
1.5 11.9 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
1.5 5.9 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
1.5 14.8 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
1.5 25.1 GO:0005149 interleukin-1 receptor binding(GO:0005149)
1.5 4.4 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
1.5 47.1 GO:0008146 sulfotransferase activity(GO:0008146)
1.5 5.9 GO:0003842 1-pyrroline-5-carboxylate dehydrogenase activity(GO:0003842)
1.4 20.1 GO:0017127 cholesterol transporter activity(GO:0017127)
1.4 55.7 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
1.4 20.9 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
1.4 4.1 GO:0016414 carnitine O-octanoyltransferase activity(GO:0008458) O-octanoyltransferase activity(GO:0016414)
1.4 9.6 GO:0019870 potassium channel inhibitor activity(GO:0019870)
1.4 4.1 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
1.4 12.2 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
1.4 4.1 GO:0000991 transcription factor activity, core RNA polymerase II binding(GO:0000991)
1.3 41.7 GO:0097110 scaffold protein binding(GO:0097110)
1.3 9.4 GO:0015526 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
1.3 10.6 GO:0047134 protein-disulfide reductase activity(GO:0047134)
1.3 6.6 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
1.3 5.2 GO:0045322 unmethylated CpG binding(GO:0045322)
1.3 6.5 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
1.3 9.2 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
1.3 5.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
1.3 12.9 GO:0048407 platelet-derived growth factor binding(GO:0048407)
1.3 3.9 GO:0008384 IkappaB kinase activity(GO:0008384)
1.3 14.0 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
1.3 6.3 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
1.2 8.7 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
1.2 7.5 GO:1990239 steroid hormone binding(GO:1990239)
1.2 28.0 GO:0050699 WW domain binding(GO:0050699)
1.2 7.3 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
1.2 4.8 GO:0019002 GMP binding(GO:0019002)
1.2 2.4 GO:0035939 microsatellite binding(GO:0035939)
1.2 11.9 GO:0005132 type I interferon receptor binding(GO:0005132)
1.2 14.2 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
1.2 2.4 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
1.2 8.2 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
1.2 3.5 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
1.2 3.5 GO:0097100 supercoiled DNA binding(GO:0097100)
1.2 2.3 GO:0001635 calcitonin gene-related peptide receptor activity(GO:0001635)
1.2 2.3 GO:0043398 HLH domain binding(GO:0043398)
1.2 8.1 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
1.2 5.8 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
1.1 3.4 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
1.1 5.7 GO:0015616 DNA translocase activity(GO:0015616)
1.1 5.7 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
1.1 5.6 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
1.1 220.3 GO:0008236 serine-type peptidase activity(GO:0008236)
1.1 7.9 GO:0008308 voltage-gated anion channel activity(GO:0008308)
1.1 4.5 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
1.1 14.3 GO:0052866 phosphatidylinositol phosphate phosphatase activity(GO:0052866)
1.1 86.3 GO:0030165 PDZ domain binding(GO:0030165)
1.1 6.6 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
1.1 4.3 GO:0015093 iron ion transmembrane transporter activity(GO:0005381) ferrous iron transmembrane transporter activity(GO:0015093)
1.1 5.4 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
1.1 13.9 GO:0001540 beta-amyloid binding(GO:0001540)
1.1 85.7 GO:0003777 microtubule motor activity(GO:0003777)
1.1 6.4 GO:0000150 recombinase activity(GO:0000150)
1.1 11.7 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
1.1 10.7 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
1.1 13.8 GO:0071837 HMG box domain binding(GO:0071837)
1.1 3.2 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
1.1 13.8 GO:0022829 wide pore channel activity(GO:0022829)
1.1 5.3 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
1.1 3.2 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
1.0 5.2 GO:0048018 receptor agonist activity(GO:0048018)
1.0 3.1 GO:0004736 pyruvate carboxylase activity(GO:0004736)
1.0 28.9 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
1.0 11.3 GO:0008641 small protein activating enzyme activity(GO:0008641)
1.0 12.2 GO:0046966 thyroid hormone receptor binding(GO:0046966)
1.0 4.0 GO:0032896 palmitoyl-CoA 9-desaturase activity(GO:0032896)
1.0 11.0 GO:0015238 drug transmembrane transporter activity(GO:0015238)
1.0 11.9 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
1.0 2.0 GO:0042910 xenobiotic transporter activity(GO:0042910)
1.0 2.9 GO:0032217 riboflavin transporter activity(GO:0032217)
1.0 6.8 GO:0003896 DNA primase activity(GO:0003896)
1.0 9.7 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
1.0 2.9 GO:1901612 cardiolipin binding(GO:1901612)
1.0 12.5 GO:0017049 GTP-Rho binding(GO:0017049)
1.0 6.7 GO:0050700 CARD domain binding(GO:0050700)
0.9 3.8 GO:0048495 Roundabout binding(GO:0048495)
0.9 4.7 GO:0005338 nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.9 5.6 GO:0005542 folic acid binding(GO:0005542)
0.9 13.8 GO:0035497 cAMP response element binding(GO:0035497)
0.9 2.8 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.9 1.8 GO:0034211 GTP-dependent protein kinase activity(GO:0034211)
0.9 2.7 GO:0004556 alpha-amylase activity(GO:0004556)
0.9 37.8 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.9 11.6 GO:0031005 filamin binding(GO:0031005)
0.9 5.3 GO:0038024 cargo receptor activity(GO:0038024)
0.9 42.7 GO:0035064 methylated histone binding(GO:0035064)
0.9 13.9 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.9 3.4 GO:0042731 PH domain binding(GO:0042731)
0.8 4.2 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.8 2.5 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.8 31.8 GO:0032947 protein complex scaffold(GO:0032947)
0.8 21.8 GO:0017091 AU-rich element binding(GO:0017091)
0.8 68.3 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.8 4.1 GO:0030492 hemoglobin binding(GO:0030492)
0.8 1.6 GO:0008432 JUN kinase binding(GO:0008432)
0.8 24.4 GO:0019205 nucleobase-containing compound kinase activity(GO:0019205)
0.8 5.7 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.8 4.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.8 2.4 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.8 36.2 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.8 8.7 GO:0008443 6-phosphofructo-2-kinase activity(GO:0003873) phosphofructokinase activity(GO:0008443)
0.8 47.8 GO:0002039 p53 binding(GO:0002039)
0.8 13.2 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.8 4.7 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.8 3.1 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.8 3.1 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity(GO:0004114)
0.8 3.0 GO:0036122 BMP binding(GO:0036122)
0.8 3.8 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.8 5.3 GO:0050897 cobalt ion binding(GO:0050897)
0.7 2.2 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.7 49.6 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.7 6.7 GO:0070182 DNA polymerase binding(GO:0070182)
0.7 2.2 GO:0071617 lysophospholipid acyltransferase activity(GO:0071617)
0.7 45.4 GO:0001948 glycoprotein binding(GO:0001948)
0.7 5.1 GO:0052832 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832)
0.7 3.6 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.7 87.0 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.7 7.1 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.7 12.7 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.7 1.4 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.7 7.0 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.7 2.1 GO:0001224 RNA polymerase II transcription cofactor binding(GO:0001224) RNA polymerase II transcription corepressor binding(GO:0001226)
0.7 7.6 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.7 5.5 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.7 3.4 GO:0031748 D1 dopamine receptor binding(GO:0031748)
0.7 2.1 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.7 2.1 GO:0005534 galactose binding(GO:0005534)
0.7 12.3 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.7 2.7 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.7 2.0 GO:0000171 ribonuclease MRP activity(GO:0000171)
0.7 2.0 GO:0042809 vitamin D receptor binding(GO:0042809)
0.6 3.9 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.6 11.6 GO:0015297 antiporter activity(GO:0015297)
0.6 13.6 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.6 14.1 GO:0051059 NF-kappaB binding(GO:0051059)
0.6 4.5 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.6 39.5 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.6 3.8 GO:0005113 patched binding(GO:0005113)
0.6 11.3 GO:0042288 MHC class I protein binding(GO:0042288)
0.6 10.7 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.6 1.9 GO:0052723 inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.6 17.9 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.6 2.5 GO:0002046 opsin binding(GO:0002046)
0.6 17.2 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.6 1.8 GO:0034190 apolipoprotein receptor binding(GO:0034190) apolipoprotein A-I receptor binding(GO:0034191)
0.6 1.8 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.6 4.6 GO:0070628 proteasome binding(GO:0070628)
0.6 5.8 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.6 2.9 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.6 6.8 GO:0046875 ephrin receptor binding(GO:0046875)
0.6 4.5 GO:0031386 protein tag(GO:0031386)
0.6 5.6 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.6 3.9 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.6 12.8 GO:0008527 taste receptor activity(GO:0008527)
0.6 3.3 GO:0070492 oligosaccharide binding(GO:0070492)
0.6 3.3 GO:0055102 lipase inhibitor activity(GO:0055102)
0.6 5.0 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.5 2.2 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.5 1.6 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.5 8.9 GO:0008327 methyl-CpG binding(GO:0008327)
0.5 12.5 GO:0017048 Rho GTPase binding(GO:0017048)
0.5 2.6 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.5 1.5 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.5 3.4 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.5 2.9 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.5 4.9 GO:0043295 glutathione binding(GO:0043295)
0.5 5.3 GO:0001618 virus receptor activity(GO:0001618)
0.5 1.0 GO:0032552 deoxyribonucleotide binding(GO:0032552)
0.5 1.0 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.5 2.7 GO:0008420 CTD phosphatase activity(GO:0008420)
0.5 2.3 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.4 1.3 GO:0042296 ISG15 transferase activity(GO:0042296)
0.4 1.7 GO:0045134 uridine-diphosphatase activity(GO:0045134)
0.4 1.7 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.4 4.2 GO:0043236 laminin binding(GO:0043236)
0.4 14.3 GO:0019905 syntaxin binding(GO:0019905)
0.4 2.1 GO:0036033 mediator complex binding(GO:0036033)
0.4 4.6 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.4 2.5 GO:0061133 endopeptidase activator activity(GO:0061133)
0.4 6.3 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.4 1.7 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.4 1.2 GO:0070883 pre-miRNA binding(GO:0070883)
0.4 4.1 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.4 3.3 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.4 8.0 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.4 12.3 GO:0016831 carboxy-lyase activity(GO:0016831)
0.4 3.2 GO:0001055 RNA polymerase II activity(GO:0001055)
0.4 1.2 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
0.4 3.5 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
0.4 1.5 GO:1990226 histone methyltransferase binding(GO:1990226)
0.4 6.8 GO:0046332 SMAD binding(GO:0046332)
0.4 8.9 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.4 0.4 GO:0035851 Krueppel-associated box domain binding(GO:0035851)
0.4 0.7 GO:0034512 box C/D snoRNA binding(GO:0034512)
0.4 9.3 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.4 22.6 GO:0031490 chromatin DNA binding(GO:0031490)
0.4 7.0 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.4 0.7 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.3 4.5 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.3 1.0 GO:0089720 caspase binding(GO:0089720)
0.3 2.1 GO:0034648 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.3 1.0 GO:0030911 TPR domain binding(GO:0030911)
0.3 1.4 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.3 62.7 GO:0030695 GTPase regulator activity(GO:0030695)
0.3 3.3 GO:0017154 semaphorin receptor activity(GO:0017154)
0.3 2.0 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.3 2.0 GO:0051400 BH domain binding(GO:0051400)
0.3 1.0 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
0.3 4.7 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.3 4.0 GO:0005402 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.3 3.4 GO:0008301 DNA binding, bending(GO:0008301)
0.3 0.9 GO:0046592 polyamine oxidase activity(GO:0046592)
0.3 0.9 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.3 3.0 GO:0005537 mannose binding(GO:0005537)
0.3 0.9 GO:0031531 thyrotropin-releasing hormone receptor binding(GO:0031531)
0.3 1.5 GO:0005123 death receptor binding(GO:0005123)
0.3 6.1 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.3 1.7 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.3 1.1 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.3 0.8 GO:0001091 RNA polymerase II basal transcription factor binding(GO:0001091) TFIID-class transcription factor binding(GO:0001094)
0.3 2.2 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.3 2.9 GO:0017160 Ral GTPase binding(GO:0017160)
0.3 2.4 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.3 73.0 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.3 0.8 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.2 0.7 GO:0098518 polynucleotide phosphatase activity(GO:0098518)
0.2 7.7 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.2 1.2 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.2 2.4 GO:0001848 complement binding(GO:0001848)
0.2 2.3 GO:0016918 retinal binding(GO:0016918)
0.2 1.2 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.2 4.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.2 1.1 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.2 4.4 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.2 0.2 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.2 0.6 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.2 17.5 GO:0008565 protein transporter activity(GO:0008565)
0.2 7.4 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.2 2.2 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.2 8.1 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.2 43.1 GO:0019904 protein domain specific binding(GO:0019904)
0.2 3.1 GO:0031491 nucleosome binding(GO:0031491)
0.2 0.4 GO:0072542 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.2 1.0 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.2 1.9 GO:0004579 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.2 0.8 GO:0005042 netrin receptor activity(GO:0005042)
0.2 0.8 GO:0032404 mismatch repair complex binding(GO:0032404)
0.2 0.9 GO:0035613 RNA stem-loop binding(GO:0035613)
0.1 0.7 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 1.6 GO:0005521 lamin binding(GO:0005521)
0.1 1.6 GO:0019104 DNA N-glycosylase activity(GO:0019104)
0.1 0.4 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
0.1 1.4 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 2.9 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.1 0.7 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.1 1.4 GO:0001221 transcription cofactor binding(GO:0001221)
0.1 0.3 GO:0004774 succinate-CoA ligase activity(GO:0004774) succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.1 0.3 GO:0035184 histone threonine kinase activity(GO:0035184)
0.1 1.4 GO:0015144 carbohydrate transmembrane transporter activity(GO:0015144) carbohydrate transporter activity(GO:1901476)
0.1 7.4 GO:0030414 peptidase inhibitor activity(GO:0030414)
0.1 0.5 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.1 3.1 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.1 1.5 GO:0016411 acylglycerol O-acyltransferase activity(GO:0016411)
0.1 0.4 GO:0019213 deacetylase activity(GO:0019213)
0.1 0.2 GO:0031708 endothelin B receptor binding(GO:0031708)
0.1 0.2 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.2 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.9 GO:0043022 ribosome binding(GO:0043022)
0.0 0.2 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.8 GO:0042393 histone binding(GO:0042393)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
10.4 176.6 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
7.9 411.3 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
7.7 207.7 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
6.4 12.8 PID S1P S1P1 PATHWAY S1P1 pathway
5.8 92.5 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
5.5 82.0 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
5.3 184.4 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
5.2 82.8 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
5.1 361.4 PID TGFBR PATHWAY TGF-beta receptor signaling
4.5 244.9 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
4.3 146.6 PID EPHB FWD PATHWAY EPHB forward signaling
4.3 107.6 PID EPHA FWDPATHWAY EPHA forward signaling
4.1 244.0 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
4.0 176.7 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
3.9 35.5 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
3.9 150.5 PID PI3KCI PATHWAY Class I PI3K signaling events
3.5 55.2 PID IGF1 PATHWAY IGF1 pathway
3.4 127.0 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
2.9 192.5 PID AR PATHWAY Coregulation of Androgen receptor activity
2.9 23.1 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
2.7 52.2 ST GA12 PATHWAY G alpha 12 Pathway
2.7 5.4 ST STAT3 PATHWAY STAT3 Pathway
2.7 78.1 PID BMP PATHWAY BMP receptor signaling
2.6 57.5 PID BCR 5PATHWAY BCR signaling pathway
2.6 31.1 PID TRAIL PATHWAY TRAIL signaling pathway
2.6 18.1 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
2.6 94.6 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
2.5 10.1 PID S1P S1P2 PATHWAY S1P2 pathway
2.5 19.8 PID ERBB4 PATHWAY ErbB4 signaling events
2.4 57.9 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
2.4 19.3 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
2.4 49.8 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
2.3 2.3 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
2.3 4.6 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
2.3 32.5 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
2.3 29.9 PID GMCSF PATHWAY GMCSF-mediated signaling events
2.3 13.5 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
2.2 30.4 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
2.1 314.7 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
2.0 4.1 PID EPO PATHWAY EPO signaling pathway
2.0 93.2 PID IL4 2PATHWAY IL4-mediated signaling events
1.9 114.9 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
1.9 34.5 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
1.9 13.4 PID IFNG PATHWAY IFN-gamma pathway
1.9 1.9 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
1.9 33.9 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
1.8 33.2 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
1.8 91.2 PID RHOA REG PATHWAY Regulation of RhoA activity
1.8 24.8 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
1.7 5.2 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
1.7 8.6 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
1.7 68.3 PID AR TF PATHWAY Regulation of Androgen receptor activity
1.6 19.4 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
1.6 12.9 PID S1P S1P4 PATHWAY S1P4 pathway
1.5 10.8 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
1.5 12.4 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
1.5 12.4 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
1.5 21.9 PID IL1 PATHWAY IL1-mediated signaling events
1.4 27.4 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
1.4 28.6 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
1.4 15.6 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
1.4 8.4 PID LPA4 PATHWAY LPA4-mediated signaling events
1.4 17.8 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
1.3 9.3 PID CXCR3 PATHWAY CXCR3-mediated signaling events
1.3 45.7 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
1.3 20.6 PID PTP1B PATHWAY Signaling events mediated by PTP1B
1.2 8.7 PID CD40 PATHWAY CD40/CD40L signaling
1.2 30.7 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
1.2 21.0 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
1.2 1.2 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
1.1 13.4 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
1.1 18.8 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
1.1 16.1 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
1.0 9.4 PID VEGFR1 PATHWAY VEGFR1 specific signals
1.0 13.5 PID IL6 7 PATHWAY IL6-mediated signaling events
1.0 103.8 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
1.0 12.9 PID FGF PATHWAY FGF signaling pathway
1.0 13.8 PID FOXM1 PATHWAY FOXM1 transcription factor network
1.0 4.9 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
1.0 7.7 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.9 10.2 PID GLYPICAN 1PATHWAY Glypican 1 network
0.9 12.8 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.9 46.6 PID NOTCH PATHWAY Notch signaling pathway
0.9 39.3 PID AURORA B PATHWAY Aurora B signaling
0.9 10.8 PID ENDOTHELIN PATHWAY Endothelins
0.9 2.7 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.9 7.0 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.9 14.6 PID ARF 3PATHWAY Arf1 pathway
0.8 5.1 ST G ALPHA S PATHWAY G alpha s Pathway
0.8 9.6 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.8 12.2 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.7 8.2 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.7 5.7 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.7 0.7 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.7 8.7 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.7 5.3 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.7 22.5 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.6 32.4 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.6 16.2 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.6 158.6 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.6 15.2 PID ILK PATHWAY Integrin-linked kinase signaling
0.5 1.6 PID IL2 1PATHWAY IL2-mediated signaling events
0.5 15.4 PID TELOMERASE PATHWAY Regulation of Telomerase
0.5 2.6 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.5 6.5 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.5 15.0 PID PLK1 PATHWAY PLK1 signaling events
0.4 5.8 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.4 5.8 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.4 13.7 PID E2F PATHWAY E2F transcription factor network
0.4 1.7 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.4 4.0 PID IL12 2PATHWAY IL12-mediated signaling events
0.4 12.6 PID CMYB PATHWAY C-MYB transcription factor network
0.4 6.4 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.3 2.5 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.3 0.6 PID FAS PATHWAY FAS (CD95) signaling pathway
0.2 9.2 PID FANCONI PATHWAY Fanconi anemia pathway
0.2 0.4 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.2 2.0 PID NETRIN PATHWAY Netrin-mediated signaling events
0.2 3.2 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.2 1.9 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.2 1.9 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.2 1.9 PID REELIN PATHWAY Reelin signaling pathway
0.2 1.5 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 1.1 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.1 1.1 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.1 1.2 PID ATM PATHWAY ATM pathway
0.1 2.9 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 0.2 PID IL27 PATHWAY IL27-mediated signaling events
0.1 1.0 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.1 0.4 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.1 0.6 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 0.2 PID NECTIN PATHWAY Nectin adhesion pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
34.0 475.6 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
29.0 956.5 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
24.1 192.7 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
19.4 194.4 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
11.0 131.7 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
8.3 132.3 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
8.0 64.0 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
7.8 31.1 REACTOME BETA DEFENSINS Genes involved in Beta defensins
7.1 64.3 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
7.0 97.6 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
6.9 13.8 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
6.4 64.3 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
6.4 12.7 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
6.2 18.6 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
6.1 84.9 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
6.0 48.1 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
5.7 211.8 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
5.7 51.2 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
5.1 56.1 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
5.0 90.8 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
4.5 514.2 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
4.4 247.7 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
4.3 82.0 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
4.2 173.7 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
4.2 66.9 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
4.1 77.4 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
4.0 72.2 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
4.0 35.7 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
3.9 39.2 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
3.9 50.9 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
3.9 77.5 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
3.8 180.3 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
3.7 67.3 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
3.7 33.4 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
3.7 233.0 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
3.7 55.3 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
3.6 21.5 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
3.6 28.4 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
3.4 16.8 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
3.2 51.6 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
3.1 166.7 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
3.1 31.4 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
3.1 34.1 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
3.0 155.3 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
3.0 109.5 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
3.0 36.2 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
3.0 152.4 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
3.0 17.8 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
2.9 44.1 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
2.9 102.2 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
2.9 2.9 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
2.9 40.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
2.9 17.2 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
2.8 8.4 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
2.8 78.4 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
2.8 47.0 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
2.7 16.0 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
2.6 5.3 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
2.6 13.0 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
2.6 160.1 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
2.5 70.8 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
2.5 10.1 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
2.5 236.1 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
2.5 46.7 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
2.4 26.3 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
2.4 4.7 REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION Genes involved in Glucagon signaling in metabolic regulation
2.4 9.4 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
2.3 51.7 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
2.3 11.7 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
2.3 30.2 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
2.3 9.2 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
2.3 36.6 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
2.3 20.4 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
2.2 11.0 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
2.1 17.0 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
2.1 8.3 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
2.0 20.5 REACTOME TCR SIGNALING Genes involved in TCR signaling
2.0 20.4 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
2.0 63.3 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
2.0 27.6 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
2.0 45.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
1.9 29.0 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
1.9 28.3 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
1.9 22.4 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
1.9 14.8 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
1.8 54.8 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
1.8 40.0 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
1.8 51.8 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
1.8 10.7 REACTOME DAG AND IP3 SIGNALING Genes involved in DAG and IP3 signaling
1.8 23.2 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
1.7 45.2 REACTOME IL 3 5 AND GM CSF SIGNALING Genes involved in Interleukin-3, 5 and GM-CSF signaling
1.7 20.6 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
1.7 22.0 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
1.7 35.1 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
1.7 10.0 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
1.6 72.5 REACTOME TRANSPORT OF GLUCOSE AND OTHER SUGARS BILE SALTS AND ORGANIC ACIDS METAL IONS AND AMINE COMPOUNDS Genes involved in Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
1.6 16.3 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
1.6 3.2 REACTOME REGULATION OF INSULIN SECRETION Genes involved in Regulation of Insulin Secretion
1.6 14.6 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
1.6 45.4 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
1.6 12.9 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
1.6 47.2 REACTOME KINESINS Genes involved in Kinesins
1.5 29.4 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
1.5 7.7 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
1.5 10.6 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
1.5 15.0 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
1.5 55.3 REACTOME SIGNALING BY ERBB2 Genes involved in Signaling by ERBB2
1.5 26.9 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
1.5 32.4 REACTOME CGMP EFFECTS Genes involved in cGMP effects
1.4 2.8 REACTOME PLATELET AGGREGATION PLUG FORMATION Genes involved in Platelet Aggregation (Plug Formation)
1.4 58.8 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
1.3 11.9 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
1.3 36.0 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
1.3 91.0 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
1.2 11.1 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
1.2 18.5 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
1.2 40.2 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
1.2 11.9 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
1.2 12.8 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
1.2 21.9 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
1.2 6.9 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
1.1 21.7 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
1.1 10.2 REACTOME AMYLOIDS Genes involved in Amyloids
1.1 20.6 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
1.1 3.2 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
1.1 24.3 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
1.0 6.1 REACTOME E2F MEDIATED REGULATION OF DNA REPLICATION Genes involved in E2F mediated regulation of DNA replication
1.0 9.2 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
1.0 5.1 REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS Genes involved in Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
1.0 55.7 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
1.0 8.1 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
1.0 3.0 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
1.0 6.8 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
1.0 3.8 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.9 37.7 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.9 23.5 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.9 42.4 REACTOME MYD88 MAL CASCADE INITIATED ON PLASMA MEMBRANE Genes involved in MyD88:Mal cascade initiated on plasma membrane
0.9 3.7 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.9 3.6 REACTOME DEFENSINS Genes involved in Defensins
0.9 6.9 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.8 5.1 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.8 48.1 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.8 9.8 REACTOME GABA B RECEPTOR ACTIVATION Genes involved in GABA B receptor activation
0.8 8.1 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.8 16.9 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.8 2.4 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.8 13.9 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.7 18.0 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.7 81.8 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.7 8.2 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.7 8.7 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.7 2.0 REACTOME TRAF6 MEDIATED INDUCTION OF NFKB AND MAP KINASES UPON TLR7 8 OR 9 ACTIVATION Genes involved in TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation
0.6 7.8 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.6 1.9 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.6 2.6 REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.6 3.8 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.6 4.4 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.6 5.3 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.6 4.6 REACTOME PERK REGULATED GENE EXPRESSION Genes involved in PERK regulated gene expression
0.6 2.3 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.5 21.9 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.5 3.7 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.5 7.4 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.5 2.0 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.5 8.4 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.5 2.3 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.5 2.7 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.4 9.9 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.4 2.2 REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.4 14.4 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.4 2.3 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.4 4.4 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.4 7.5 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.3 8.2 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.3 2.4 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.3 7.7 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.3 5.7 REACTOME LIPID DIGESTION MOBILIZATION AND TRANSPORT Genes involved in Lipid digestion, mobilization, and transport
0.2 2.7 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.2 4.4 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.2 1.2 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.2 1.1 REACTOME SIGNALING BY EGFR IN CANCER Genes involved in Signaling by EGFR in Cancer
0.2 0.9 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.2 0.5 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.1 1.6 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.1 1.6 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.1 0.9 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.1 0.1 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.1 2.8 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.1 1.0 REACTOME TOLL RECEPTOR CASCADES Genes involved in Toll Receptor Cascades
0.1 0.9 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 1.5 REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.1 0.4 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 0.3 REACTOME HOST INTERACTIONS OF HIV FACTORS Genes involved in Host Interactions of HIV factors
0.1 0.7 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.1 0.7 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.1 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events