Project

GSE53960: rat RNA-Seq transcriptomic Bodymap

Navigation
Downloads

Results for Scrt1

Z-value: 1.35

Motif logo

Transcription factors associated with Scrt1

Gene Symbol Gene ID Gene Info
ENSRNOG00000025594 scratch family transcriptional repressor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Scrt1rn6_v1_chr7_-_117587103_117587103-0.501.8e-21Click!

Activity profile of Scrt1 motif

Sorted Z-values of Scrt1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_123557501 63.51 ENSRNOT00000075042
ENSRNOT00000085966
aldehyde dehydrogenase 1 family, member L1
chr2_+_60337667 60.76 ENSRNOT00000024035
alanine-glyoxylate aminotransferase 2
chr1_+_213511874 57.88 ENSRNOT00000078080
ENSRNOT00000016883
cytochrome P450, family 2, subfamily e, polypeptide 1
chr6_-_127630734 57.51 ENSRNOT00000089931
serpin family A member 1
chr19_+_52077501 54.48 ENSRNOT00000079240
oxidative stress induced growth inhibitor 1
chr19_+_37052556 50.88 ENSRNOT00000019072
carboxylesterase 2H
chr3_-_14112851 50.40 ENSRNOT00000092736
complement C5
chr10_+_71159869 43.61 ENSRNOT00000075977
ENSRNOT00000047427
HNF1 homeobox B
chr1_-_189199376 40.53 ENSRNOT00000021027
uromodulin
chr13_-_99287887 38.79 ENSRNOT00000004780
epoxide hydrolase 1
chr3_+_159936856 38.29 ENSRNOT00000078703
hepatocyte nuclear factor 4, alpha
chr2_-_195935878 35.11 ENSRNOT00000028440
cingulin
chr7_-_11186130 35.08 ENSRNOT00000075038
small integral membrane protein 24
chr11_-_67037115 34.15 ENSRNOT00000003137
immunoglobulin-like domain containing receptor 1
chr6_+_128050250 32.95 ENSRNOT00000077517
ENSRNOT00000013961
Ab1-233
chr14_+_22517774 32.85 ENSRNOT00000047655
UDP-glucuronosyltransferase 2 family, member 37
chr7_+_14891001 30.72 ENSRNOT00000041034
cytochrome P450, family 4, subfamily f, polypeptide 4
chr4_-_176231344 30.48 ENSRNOT00000049154
solute carrier organic anion transporter family, member 1a1
chr8_-_130550388 29.86 ENSRNOT00000026355
cytochrome P450, family 8, subfamily b, polypeptide 1
chr7_+_94130852 28.95 ENSRNOT00000011485
mal, T-cell differentiation protein 2
chr2_-_238468435 28.89 ENSRNOT00000055537
rho guanine nucleotide exchange factor 38-like
chr1_-_89399039 28.76 ENSRNOT00000028585
ENSRNOT00000044678
lipolysis stimulated lipoprotein receptor
chr19_+_487723 28.58 ENSRNOT00000061734
carboxylesterase 2J
chr2_+_181987217 28.13 ENSRNOT00000034521
fibrinogen gamma chain
chr1_+_216677373 27.45 ENSRNOT00000027925
solute carrier family 22, member 18
chr2_+_227455722 27.41 ENSRNOT00000064809
SEC24 homolog D, COPII coat complex component
chr1_+_88955440 27.12 ENSRNOT00000091101
proline dehydrogenase 2
chr4_+_153876149 26.43 ENSRNOT00000018083
solute carrier family 6 member 13
chr11_+_62584959 26.24 ENSRNOT00000071065
GRAM domain containing 1C
chr3_-_1549189 26.16 ENSRNOT00000086447
paired box 8
chr6_-_127534247 26.00 ENSRNOT00000012500
serpin family A member 6
chr1_+_88955135 25.88 ENSRNOT00000083550
proline dehydrogenase 2
chr4_-_167552973 25.87 ENSRNOT00000007806
kidney androgen regulated protein
chr3_-_101474890 25.71 ENSRNOT00000091869
gamma-butyrobetaine hydroxylase 1
chr7_-_101140308 25.29 ENSRNOT00000006279
family with sequence similarity 84, member B
chr2_-_238369692 24.16 ENSRNOT00000041583
Rho guanine nucleotide exchange factor 38
chr16_+_6970342 24.02 ENSRNOT00000061294
ENSRNOT00000048344
inter-alpha-trypsin inhibitor heavy chain family, member 4
chr1_-_54748763 23.90 ENSRNOT00000074549
protein MAL2-like
chr8_-_32280869 23.73 ENSRNOT00000009139
suppression of tumorigenicity 14
chr10_+_62981297 23.48 ENSRNOT00000031618
EF-hand calcium binding domain 5
chr12_-_22194287 23.15 ENSRNOT00000082895
ENSRNOT00000001905
transferrin receptor 2
chr1_+_277689729 22.36 ENSRNOT00000051834
von Willebrand factor A domain containing 2
chr2_-_93641497 22.19 ENSRNOT00000013720
charged multivesicular body protein 4C
chr2_-_30577218 22.15 ENSRNOT00000024674
occludin
chr1_+_242959488 21.93 ENSRNOT00000015668
dedicator of cytokinesis 8
chr16_-_19942343 21.67 ENSRNOT00000087162
ENSRNOT00000091906
bone marrow stromal cell antigen 2
chr7_-_116425003 21.47 ENSRNOT00000076694
lymphocyte antigen 6 complex, locus I
chr11_+_74057361 21.24 ENSRNOT00000048746
carboxypeptidase N subunit 2
chr5_-_169331163 20.89 ENSRNOT00000042301
espin
chr17_+_76079720 20.77 ENSRNOT00000073933
proline and serine rich 2
chr6_-_50846965 20.64 ENSRNOT00000087300
solute carrier family 26 member 4
chr2_-_186333805 20.25 ENSRNOT00000022150
CD1d1 molecule
chr5_-_119564846 20.14 ENSRNOT00000012977
cytochrome P450, family 2, subfamily j, polypeptide 4
chr1_+_219764001 20.14 ENSRNOT00000082388
pyruvate carboxylase
chr7_-_143016040 19.86 ENSRNOT00000029697
keratin 80
chr1_-_199395363 19.75 ENSRNOT00000090368
ENSRNOT00000026587
protease, serine, 36
chr1_-_89369960 19.42 ENSRNOT00000028545
hepcidin antimicrobial peptide
chr3_-_23066658 19.33 ENSRNOT00000018751
nuclear receptor subfamily 6, group A, member 1
chr20_+_13670066 18.36 ENSRNOT00000031400
stromelysin-3
chr19_-_38120578 18.21 ENSRNOT00000026873
epithelial splicing regulatory protein 2
chr5_-_75005567 17.60 ENSRNOT00000016068
hypothetical protein LOC685849
chr7_-_3386522 17.16 ENSRNOT00000010760
methyltransferase like 7B
chr10_+_43633035 16.97 ENSRNOT00000077764
interferon gamma induced GTPase
chr2_-_53140637 16.84 ENSRNOT00000060492
coiled-coil domain containing 152
chr9_+_88357556 16.84 ENSRNOT00000020669
collagen type IV alpha 3 chain
chr2_+_196487656 16.68 ENSRNOT00000028699
ENSRNOT00000080324
ceramide synthase 2
chr1_-_253185533 16.30 ENSRNOT00000067822
pantothenate kinase 1
chr17_+_76079907 16.29 ENSRNOT00000092710
proline and serine rich 2
chr16_+_74531564 16.20 ENSRNOT00000078971
solute carrier family 25 member 15
chr2_+_93669765 16.19 ENSRNOT00000045438
solute carrier family 10, member 5
chr1_-_82120902 16.18 ENSRNOT00000027684
Ets2 repressor factor
chr3_-_113405829 15.97 ENSRNOT00000036823
elongation factor for RNA polymerase II 3
chr6_+_115170865 15.75 ENSRNOT00000005671
thyroid stimulating hormone receptor
chr18_-_11858744 15.67 ENSRNOT00000061417
ENSRNOT00000082891
desmocollin 2
chr7_+_59349745 15.55 ENSRNOT00000085334
protein tyrosine phosphatase, receptor type, B
chr13_+_89826254 15.35 ENSRNOT00000006141
F11 receptor
chr17_+_57075218 15.17 ENSRNOT00000089536
cAMP responsive element modulator
chr13_-_83457888 14.30 ENSRNOT00000076289
ENSRNOT00000004065
SFT2 domain containing 2
chr7_+_143754892 14.26 ENSRNOT00000085896
sterol O-acyltransferase 2
chr8_+_52729003 14.26 ENSRNOT00000081738
neurexophilin and PC-esterase domain family, member 4
chr10_+_103713045 14.10 ENSRNOT00000004351
SLC9A3 regulator 1
chr20_+_20519031 14.07 ENSRNOT00000000780

chr3_+_114900343 13.60 ENSRNOT00000068129
sulfide quinone reductase-like (yeast)
chr7_+_130296897 13.56 ENSRNOT00000044854
adrenomedullin 2
chr20_+_55594676 13.38 ENSRNOT00000057010
single-minded family bHLH transcription factor 1
chr10_-_90415070 13.37 ENSRNOT00000055179
integrin subunit alpha 2b
chr1_+_213766758 13.18 ENSRNOT00000005645
interferon induced transmembrane protein 1
chr8_+_117068582 13.12 ENSRNOT00000073559
aminomethyltransferase
chr1_+_56242346 13.04 ENSRNOT00000019317
SPARC related modular calcium binding 2
chr1_+_101265272 12.97 ENSRNOT00000051280
similar to Orphan sodium- and chloride-dependent neurotransmitter transporter NTT5 (Solute carrier family 6 member 16)
chr9_-_110225486 12.63 ENSRNOT00000045096
ephrin A5
chr7_-_117068332 12.44 ENSRNOT00000082433
family with sequence similarity 83, member H
chrX_-_23649466 12.42 ENSRNOT00000059431
shroom family member 2
chr10_-_47666921 12.34 ENSRNOT00000086579
solute carrier family 47 member 1
chr10_-_48860902 12.21 ENSRNOT00000004127
centromere protein V
chr16_-_71125316 12.12 ENSRNOT00000020900
phospholipid phosphatase 5
chr13_+_103396314 12.01 ENSRNOT00000049499
solute carrier family 30, member 10
chr10_-_89374516 11.99 ENSRNOT00000028084
vesicle amine transport 1
chr1_-_20155960 11.88 ENSRNOT00000061389
sterile alpha motif domain containing 3
chr7_-_143793774 11.69 ENSRNOT00000079678
cysteine sulfinic acid decarboxylase
chrX_+_16337102 11.38 ENSRNOT00000003954
cyclin B3
chr2_+_60169517 11.23 ENSRNOT00000080974
prolactin receptor
chr9_-_19372673 11.19 ENSRNOT00000073667
ENSRNOT00000079517
chloride intracellular channel 5
chr8_+_70712513 11.14 ENSRNOT00000079548
poly (ADP-ribose) polymerase family, member 16
chr1_-_73660593 10.88 ENSRNOT00000038802
leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5
chr16_-_82099991 10.83 ENSRNOT00000089447
ATPase phospholipid transporting 11A
chr4_+_114760879 10.71 ENSRNOT00000090713

chr10_+_84966989 10.63 ENSRNOT00000013580
secernin 2
chr1_+_282567674 10.59 ENSRNOT00000090543
carboxylesterase 2I
chr8_-_114617466 10.57 ENSRNOT00000082992
ENSRNOT00000038160
collagen type VI alpha 5 chain
chr11_-_88972176 10.53 ENSRNOT00000002498
plakophilin 2
chr2_+_187162017 10.51 ENSRNOT00000080693
insulin receptor-related receptor
chr18_-_55992885 10.46 ENSRNOT00000025881
N-deacetylase and N-sulfotransferase 1
chr7_+_141953794 10.32 ENSRNOT00000041938
transmembrane protease, serine 12
chr11_+_61661724 10.29 ENSRNOT00000079423
zinc finger, DHHC-type containing 23
chr10_+_36098051 10.21 ENSRNOT00000083971
ADAM metallopeptidase with thrombospondin type 1 motif, 2
chr10_+_88979383 10.04 ENSRNOT00000052157
N-acetyl-alpha-glucosaminidase
chr1_+_217349493 9.94 ENSRNOT00000092278
ENSRNOT00000092579
SH3 and multiple ankyrin repeat domains 2
chrX_-_107762590 9.89 ENSRNOT00000072739
ESX homeobox 1
chr12_-_41497610 9.79 ENSRNOT00000001860
IQ motif containing D
chr15_+_108526014 9.69 ENSRNOT00000017211
transmembrane 9 superfamily member 2
chr2_-_188412329 9.60 ENSRNOT00000033917
ENSRNOT00000080185
farnesyl diphosphate synthase
chr2_-_188413219 9.50 ENSRNOT00000065065
farnesyl diphosphate synthase
chr10_-_14443010 9.44 ENSRNOT00000022142
transmembrane protein 204
chr17_-_70234103 9.37 ENSRNOT00000024200
ankyrin repeat and SOCS box-containing 13
chr8_+_62341613 9.36 ENSRNOT00000066923
secretory carrier membrane protein 2
chr9_-_71445739 9.34 ENSRNOT00000019698
frizzled class receptor 5
chr5_-_59149625 9.23 ENSRNOT00000040641
ENSRNOT00000084216
sperm associated antigen 8
chr7_+_117643206 9.18 ENSRNOT00000077588
aarF domain containing kinase 5
chr5_-_122746839 9.13 ENSRNOT00000032126
solute carrier family 35 member D1
chr1_+_11963836 8.98 ENSRNOT00000074325

chr5_+_28850950 8.71 ENSRNOT00000009759
transmembrane protein 64
chr15_-_5486590 8.70 ENSRNOT00000040447

chr10_-_14022452 8.62 ENSRNOT00000016554
neuropeptide W
chr4_+_117780533 8.56 ENSRNOT00000021211
Tp53rk binding protein
chr2_-_188689392 8.52 ENSRNOT00000027986
DC-STAMP domain containing 1
chr6_+_12362813 8.52 ENSRNOT00000022370
stonin 1
chr19_-_44101365 8.49 ENSRNOT00000082182
transmembrane protein 170A
chr13_+_48644604 8.49 ENSRNOT00000084259
ENSRNOT00000073669
RAB29, member RAS oncogene family
chr17_+_57074525 8.48 ENSRNOT00000020012
ENSRNOT00000074146
cAMP responsive element modulator
chr12_+_48101673 8.46 ENSRNOT00000065060
forkhead box N4
chr13_-_90832138 8.45 ENSRNOT00000010930
immunoglobulin superfamily, member 9
chr1_+_56288832 8.44 ENSRNOT00000079718
SPARC related modular calcium binding 2
chr1_+_100086520 8.28 ENSRNOT00000025723
kallikrein 1
chr4_-_132740938 8.10 ENSRNOT00000007185
RING1 and YY1 binding protein
chr3_-_8659102 7.97 ENSRNOT00000050908
zinc finger, DHHC-type containing 12
chr8_-_22874637 7.96 ENSRNOT00000064551
ENSRNOT00000090424
dedicator of cytokinesis 6
chr2_+_187697523 7.93 ENSRNOT00000026153
glycosylated lysosomal membrane protein
chr12_-_45801842 7.86 ENSRNOT00000078837

chr1_+_78820262 7.72 ENSRNOT00000022441
G protein subunit gamma 8
chr12_+_46042413 7.70 ENSRNOT00000046882
coiled-coil domain containing 60
chr1_+_219243447 7.50 ENSRNOT00000024129
T-box 10
chr9_+_100511610 7.49 ENSRNOT00000033233
anoctamin 7
chr10_+_109904259 7.45 ENSRNOT00000073886
ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
chr19_-_41161765 7.42 ENSRNOT00000023117
Hydin, axonemal central pair apparatus protein
chr2_+_208749996 7.34 ENSRNOT00000086321
chitinase, acidic
chr18_+_24540659 7.33 ENSRNOT00000061074
AMMECR1 like
chr2_-_29121104 7.33 ENSRNOT00000020543
transportin 1
chr5_+_28480023 7.28 ENSRNOT00000075067
ENSRNOT00000093754
uncharacterized LOC100912373
chr4_-_55527092 7.27 ENSRNOT00000087407
ENSRNOT00000010223
zinc finger protein 800
chr7_+_129812789 7.19 ENSRNOT00000006357
cysteine-rich with EGF-like domains 2
chr17_-_4454701 7.11 ENSRNOT00000080750
ENSRNOT00000066950
death associated protein kinase 1
chr6_+_22167919 6.99 ENSRNOT00000007655
NLR family, CARD domain containing 4
chr1_+_221644867 6.97 ENSRNOT00000054830
EH-domain containing 1
chr9_+_24095751 6.92 ENSRNOT00000018177
phosphoglycerate kinase 2
chr3_-_48604097 6.90 ENSRNOT00000009620
interferon induced with helicase C domain 1
chr2_-_198439454 6.80 ENSRNOT00000028780
Fc fragment of IgG receptor Ia
chr1_-_198267093 6.76 ENSRNOT00000047477
similar to RIKEN cDNA 4930451I11
chr1_+_177569618 6.75 ENSRNOT00000090042
TEA domain transcription factor 1
chr7_+_11295892 6.61 ENSRNOT00000089004
tight junction protein 3
chr9_-_14724093 6.48 ENSRNOT00000018500
triggering receptor expressed on myeloid cells 3
chr19_-_10976396 6.46 ENSRNOT00000073239
NLR family, CARD domain containing 5
chr5_-_33574596 6.45 ENSRNOT00000008281
copine 3
chr2_+_208750356 6.42 ENSRNOT00000041562
chitinase, acidic
chr17_-_45727146 6.42 ENSRNOT00000083706
olfactory receptor 2W1-like
chr14_+_81819415 6.39 ENSRNOT00000018515
ENSRNOT00000075863
ENSRNOT00000077060
Max dimerization protein 4
chr10_+_87788458 6.14 ENSRNOT00000042020
keratin-associated protein 9-1-like
chr3_-_177205836 6.12 ENSRNOT00000034209
LKAAEAR motif containing 1
chr1_-_167911961 6.03 ENSRNOT00000025097
olfactory receptor 59
chr9_+_41045363 5.96 ENSRNOT00000066284
cripto, FRL-1, cryptic family 1
chr10_+_36589181 5.83 ENSRNOT00000045596
zinc finger protein 354A
chr6_+_34094306 5.80 ENSRNOT00000051970
WD repeat domain 35
chr1_+_154377447 5.79 ENSRNOT00000084268
ENSRNOT00000092086
ENSRNOT00000091470
ENSRNOT00000025415
phosphatidylinositol binding clathrin assembly protein
chr8_+_4440876 5.72 ENSRNOT00000049325
ENSRNOT00000076529
ENSRNOT00000076748
platelet derived growth factor D
chr1_+_205842489 5.69 ENSRNOT00000081610
fibronectin type 3 and ankyrin repeat domains 1
chrX_-_104814145 5.68 ENSRNOT00000004909
synaptotagmin-like 4
chr1_-_213534641 5.66 ENSRNOT00000033074
synaptonemal complex central element protein 1
chr1_+_276659542 5.64 ENSRNOT00000019681
transcription factor 7 like 2
chr2_+_113696154 5.63 ENSRNOT00000039308
ENSRNOT00000091545
phospholipase D1
chr7_+_137155481 5.61 ENSRNOT00000089895
anoctamin 6
chrX_-_152237347 5.59 ENSRNOT00000087138
ENSRNOT00000077750
gamma-aminobutyric acid type A receptor epsilon subunit
chr2_-_197814808 5.58 ENSRNOT00000074156
ADAMTS-like 4
chr3_-_123179644 5.54 ENSRNOT00000028835
leucine zipper tumor suppressor family member 3
chr10_+_55478298 5.48 ENSRNOT00000038454
ring finger protein 222
chr2_-_25190495 5.43 ENSRNOT00000024202
S100 calcium binding protein Z
chr18_-_24693481 5.38 ENSRNOT00000021708
SFT2 domain containing 3
chr5_-_126221916 5.33 ENSRNOT00000052130
lymphocyte expansion molecule
chr10_+_87782376 5.32 ENSRNOT00000017415
hypothetical protein LOC680396
chr5_-_152458023 5.30 ENSRNOT00000031225
connector enhancer of kinase suppressor of Ras 1
chr12_+_22153983 5.23 ENSRNOT00000080775
ENSRNOT00000001894
procollagen C-endopeptidase enhancer

Network of associatons between targets according to the STRING database.

First level regulatory network of Scrt1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
21.2 63.5 GO:0009397 folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
20.3 60.8 GO:0019265 glycine biosynthetic process, by transamination of glyoxylate(GO:0019265)
19.2 57.5 GO:0033986 response to methanol(GO:0033986)
17.7 53.0 GO:0010133 proline catabolic process to glutamate(GO:0010133)
14.5 43.6 GO:0061215 mesonephros morphogenesis(GO:0061206) mesonephric nephron development(GO:0061215) mesonephric nephron morphogenesis(GO:0061228) mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis(GO:0061235) regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061295) negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061296) mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:1901146)
11.6 57.9 GO:0016098 monoterpenoid metabolic process(GO:0016098)
10.1 40.5 GO:0072021 ascending thin limb development(GO:0072021) metanephric ascending thin limb development(GO:0072218)
9.6 38.3 GO:0042977 regulation of activation of JAK2 kinase activity(GO:0010534) activation of JAK2 kinase activity(GO:0042977) negative regulation of activation of JAK2 kinase activity(GO:1902569)
8.7 26.2 GO:0070460 thyroid-stimulating hormone secretion(GO:0070460) regulation of thyroid-stimulating hormone secretion(GO:2000612)
8.4 50.4 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
7.5 22.4 GO:0007161 calcium-independent cell-matrix adhesion(GO:0007161)
7.2 21.7 GO:1901252 negative regulation of dendritic cell cytokine production(GO:0002731) regulation of intracellular transport of viral material(GO:1901252)
6.7 20.2 GO:0048007 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
5.9 23.7 GO:0060671 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
5.9 52.8 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
5.8 23.1 GO:0097460 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
5.6 16.7 GO:1903976 negative regulation of glial cell migration(GO:1903976)
5.5 22.2 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
5.2 15.7 GO:1905225 response to thyrotropin-releasing hormone(GO:1905225)
5.0 20.1 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
4.9 19.4 GO:1903413 regulation of iron ion transmembrane transport(GO:0034759) negative regulation of iron ion transmembrane transport(GO:0034760) cellular response to bile acid(GO:1903413)
4.7 14.1 GO:0034635 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
4.3 25.7 GO:0045329 carnitine biosynthetic process(GO:0045329)
4.0 12.0 GO:0071579 regulation of zinc ion transport(GO:0071579)
3.9 11.7 GO:0042412 taurine biosynthetic process(GO:0042412)
3.8 19.1 GO:0033383 geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384)
3.5 10.5 GO:0071469 cellular response to alkaline pH(GO:0071469)
3.3 13.1 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
3.3 26.2 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
3.2 16.2 GO:0000066 mitochondrial ornithine transport(GO:0000066)
3.2 38.8 GO:0034312 diol biosynthetic process(GO:0034312)
3.1 9.3 GO:0060061 Spemann organizer formation(GO:0060061)
3.0 9.1 GO:0090481 pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
3.0 20.9 GO:0030046 parallel actin filament bundle assembly(GO:0030046)
2.9 8.7 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
2.8 5.6 GO:2001226 negative regulation of chloride transport(GO:2001226)
2.8 11.1 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
2.8 13.8 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
2.6 13.1 GO:0061589 calcium activated phosphatidylserine scrambling(GO:0061589)
2.6 10.5 GO:0030210 heparin biosynthetic process(GO:0030210)
2.4 12.2 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
2.3 28.1 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
2.3 20.6 GO:0015705 iodide transport(GO:0015705)
2.3 6.8 GO:0001788 antibody-dependent cellular cytotoxicity(GO:0001788)
2.2 22.1 GO:0070673 response to interleukin-18(GO:0070673)
2.0 6.0 GO:1900135 positive regulation of renin secretion into blood stream(GO:1900135)
2.0 12.0 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
2.0 16.0 GO:0042795 snRNA transcription from RNA polymerase II promoter(GO:0042795)
1.9 5.8 GO:1902963 regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902959) positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963) regulation of aspartic-type peptidase activity(GO:1905245) positive regulation of aspartic-type peptidase activity(GO:1905247)
1.9 5.7 GO:2000437 regulation of monocyte extravasation(GO:2000437)
1.9 5.6 GO:0010909 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909)
1.9 7.4 GO:1904158 axonemal central apparatus assembly(GO:1904158)
1.8 3.7 GO:0040038 polar body extrusion after meiotic divisions(GO:0040038)
1.8 16.2 GO:0010668 ectodermal cell differentiation(GO:0010668)
1.7 39.8 GO:0006855 drug transmembrane transport(GO:0006855)
1.7 28.8 GO:0060856 establishment of blood-brain barrier(GO:0060856)
1.6 6.5 GO:0070945 neutrophil mediated killing of gram-negative bacterium(GO:0070945)
1.6 6.5 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
1.6 6.5 GO:0038128 ERBB2 signaling pathway(GO:0038128)
1.6 14.3 GO:0034379 very-low-density lipoprotein particle assembly(GO:0034379)
1.5 6.0 GO:0060460 left lung morphogenesis(GO:0060460)
1.4 29.1 GO:0035634 response to stilbenoid(GO:0035634)
1.3 16.8 GO:0032836 glomerular basement membrane development(GO:0032836)
1.3 7.6 GO:0072386 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
1.3 20.1 GO:0043651 linoleic acid metabolic process(GO:0043651)
1.2 11.2 GO:0038161 prolactin signaling pathway(GO:0038161)
1.2 3.5 GO:0060488 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
1.1 3.3 GO:0042489 negative regulation of odontogenesis of dentin-containing tooth(GO:0042489)
1.1 4.3 GO:0070370 cellular heat acclimation(GO:0070370)
1.0 7.3 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
1.0 11.1 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
1.0 7.0 GO:0070269 pyroptosis(GO:0070269)
1.0 21.9 GO:0036336 dendritic cell migration(GO:0036336)
1.0 7.0 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
1.0 6.9 GO:0039530 MDA-5 signaling pathway(GO:0039530)
1.0 12.6 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.9 11.2 GO:0002024 diet induced thermogenesis(GO:0002024)
0.9 2.7 GO:0098758 response to interleukin-8(GO:0098758) cellular response to interleukin-8(GO:0098759)
0.9 16.3 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.9 12.4 GO:0045217 cell-cell junction maintenance(GO:0045217)
0.9 26.4 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.9 4.3 GO:0060014 granulosa cell differentiation(GO:0060014)
0.9 15.4 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.9 2.6 GO:0032053 ciliary basal body organization(GO:0032053) positive regulation of protein localization to cilium(GO:1903566)
0.8 8.5 GO:0035881 amacrine cell differentiation(GO:0035881)
0.8 10.0 GO:0046548 retinal rod cell development(GO:0046548)
0.8 16.2 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.8 24.0 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.8 18.4 GO:0030574 collagen catabolic process(GO:0030574)
0.8 9.9 GO:0098880 maintenance of postsynaptic specialization structure(GO:0098880) maintenance of postsynaptic density structure(GO:0099562)
0.8 3.8 GO:0015755 fructose transport(GO:0015755) cellular response to fructose stimulus(GO:0071332)
0.8 5.3 GO:0035740 CD8-positive, alpha-beta T cell proliferation(GO:0035740)
0.7 7.5 GO:0021894 cerebral cortex GABAergic interneuron development(GO:0021894)
0.7 5.1 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.7 3.3 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.7 4.0 GO:0015860 purine nucleoside transmembrane transport(GO:0015860)
0.6 5.8 GO:0007000 nucleolus organization(GO:0007000)
0.6 10.8 GO:0045332 phospholipid translocation(GO:0045332)
0.6 13.2 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.6 5.6 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.6 20.9 GO:0018345 protein palmitoylation(GO:0018345)
0.6 18.2 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.6 8.5 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.6 3.6 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.6 2.9 GO:0000706 meiotic DNA double-strand break processing(GO:0000706)
0.6 1.7 GO:0019303 D-ribose catabolic process(GO:0019303)
0.6 5.8 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.6 35.1 GO:0003382 epithelial cell morphogenesis(GO:0003382)
0.5 1.6 GO:0032258 CVT pathway(GO:0032258)
0.5 8.1 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.5 7.3 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.5 2.6 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.5 7.1 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.5 17.0 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.5 5.5 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.5 23.7 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.5 1.4 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.5 6.7 GO:1902459 positive regulation of stem cell population maintenance(GO:1902459)
0.4 2.7 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.4 1.3 GO:1902167 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902167)
0.4 2.2 GO:0071955 recycling endosome to Golgi transport(GO:0071955)
0.4 1.3 GO:1904618 transitional stage B cell differentiation(GO:0002332) transitional one stage B cell differentiation(GO:0002333) glomerular visceral epithelial cell apoptotic process(GO:1903210) positive regulation of actin filament binding(GO:1904531) positive regulation of actin binding(GO:1904618)
0.4 9.9 GO:0060713 labyrinthine layer morphogenesis(GO:0060713)
0.4 7.3 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.4 4.2 GO:0044821 telomere tethering at nuclear periphery(GO:0034398) meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.4 1.5 GO:0034421 post-translational protein acetylation(GO:0034421)
0.3 8.9 GO:0001945 lymph vessel development(GO:0001945)
0.3 34.2 GO:0090277 positive regulation of peptide hormone secretion(GO:0090277)
0.3 4.8 GO:2000188 regulation of cholesterol homeostasis(GO:2000188)
0.3 5.0 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.3 2.5 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
0.3 4.7 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
0.3 8.3 GO:0002675 positive regulation of acute inflammatory response(GO:0002675)
0.3 12.9 GO:0044380 protein localization to cytoskeleton(GO:0044380)
0.3 26.7 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.3 2.8 GO:0003334 keratinocyte development(GO:0003334)
0.2 4.2 GO:0006662 glycerol ether metabolic process(GO:0006662)
0.2 2.2 GO:0000270 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.2 3.9 GO:0001921 positive regulation of receptor recycling(GO:0001921)
0.2 1.4 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.2 1.2 GO:0031642 negative regulation of myelination(GO:0031642)
0.2 0.5 GO:1900063 regulation of peroxisome organization(GO:1900063)
0.2 3.6 GO:0019236 response to pheromone(GO:0019236)
0.2 2.8 GO:0070234 positive regulation of T cell apoptotic process(GO:0070234)
0.2 1.9 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.2 0.6 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.2 10.8 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
0.2 32.8 GO:0030308 negative regulation of cell growth(GO:0030308)
0.2 2.8 GO:0060337 type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.2 5.7 GO:0070193 synaptonemal complex assembly(GO:0007130) synaptonemal complex organization(GO:0070193)
0.2 0.5 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.2 16.8 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.2 1.6 GO:1990403 embryonic brain development(GO:1990403)
0.2 0.2 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.1 13.4 GO:0072164 ureteric bud development(GO:0001657) mesonephric epithelium development(GO:0072163) mesonephric tubule development(GO:0072164)
0.1 0.9 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.1 4.6 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.1 30.3 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.1 0.6 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.1 3.7 GO:0045070 positive regulation of viral genome replication(GO:0045070)
0.1 5.7 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.1 2.4 GO:0048240 sperm capacitation(GO:0048240)
0.1 4.9 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.1 5.9 GO:0032092 positive regulation of protein binding(GO:0032092)
0.1 0.6 GO:2000074 regulation of type B pancreatic cell development(GO:2000074) negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.1 0.5 GO:0071034 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.1 1.3 GO:0030194 positive regulation of blood coagulation(GO:0030194) positive regulation of hemostasis(GO:1900048)
0.1 1.4 GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
0.1 11.4 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 1.0 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 1.1 GO:0035329 hippo signaling(GO:0035329)
0.1 5.9 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.1 4.2 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.1 2.5 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.1 3.4 GO:0030520 intracellular estrogen receptor signaling pathway(GO:0030520)
0.1 2.3 GO:0048635 negative regulation of muscle organ development(GO:0048635)
0.1 1.6 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.1 3.2 GO:0032755 positive regulation of interleukin-6 production(GO:0032755)
0.1 5.5 GO:0008033 tRNA processing(GO:0008033)
0.1 0.5 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.1 1.2 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.1 4.2 GO:2000045 regulation of G1/S transition of mitotic cell cycle(GO:2000045)
0.0 0.1 GO:2000768 glomerular parietal epithelial cell differentiation(GO:0072139) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
0.0 1.9 GO:0042107 cytokine metabolic process(GO:0042107)
0.0 7.3 GO:0032259 methylation(GO:0032259)
0.0 2.1 GO:0007586 digestion(GO:0007586)
0.0 1.1 GO:0001541 ovarian follicle development(GO:0001541)
0.0 0.6 GO:0000082 G1/S transition of mitotic cell cycle(GO:0000082)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
12.6 62.9 GO:0061689 tricellular tight junction(GO:0061689)
7.2 50.4 GO:0005579 membrane attack complex(GO:0005579)
3.9 23.1 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
3.5 28.1 GO:0005577 fibrinogen complex(GO:0005577)
3.2 22.2 GO:0090543 Flemming body(GO:0090543)
2.5 35.0 GO:0032426 stereocilium tip(GO:0032426)
2.3 7.0 GO:0031095 platelet dense tubular network membrane(GO:0031095)
2.2 6.7 GO:0071148 TEAD-1-YAP complex(GO:0071148)
2.1 16.8 GO:0098645 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
2.0 27.4 GO:0030127 COPII vesicle coat(GO:0030127)
1.9 19.4 GO:0045179 apical cortex(GO:0045179)
1.9 5.6 GO:1990907 beta-catenin-TCF complex(GO:1990907)
1.8 38.8 GO:0030057 desmosome(GO:0030057)
1.7 8.5 GO:0020003 symbiont-containing vacuole(GO:0020003)
1.5 7.4 GO:1990716 axonemal central apparatus(GO:1990716)
1.4 7.0 GO:0072557 IPAF inflammasome complex(GO:0072557)
1.4 27.1 GO:0005614 interstitial matrix(GO:0005614)
1.1 11.5 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
1.0 22.1 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.9 50.6 GO:0060170 ciliary membrane(GO:0060170)
0.8 5.8 GO:0030991 intraciliary transport particle A(GO:0030991)
0.7 12.6 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.7 8.6 GO:0000801 central element(GO:0000801)
0.6 11.1 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.5 7.6 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.5 1.6 GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.5 35.1 GO:0016459 myosin complex(GO:0016459)
0.5 5.8 GO:0097418 neurofibrillary tangle(GO:0097418)
0.5 3.7 GO:0071203 WASH complex(GO:0071203)
0.5 3.2 GO:0036128 CatSper complex(GO:0036128)
0.4 61.8 GO:0031227 intrinsic component of endoplasmic reticulum membrane(GO:0031227)
0.4 51.8 GO:0072562 blood microparticle(GO:0072562)
0.4 23.6 GO:0034707 chloride channel complex(GO:0034707)
0.4 4.2 GO:0070187 telosome(GO:0070187)
0.4 5.7 GO:0035253 ciliary rootlet(GO:0035253)
0.4 12.2 GO:0051233 spindle midzone(GO:0051233)
0.4 21.1 GO:0008023 transcription elongation factor complex(GO:0008023)
0.4 2.6 GO:0060205 cytoplasmic membrane-bounded vesicle lumen(GO:0060205)
0.3 9.4 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.3 2.7 GO:0042629 mast cell granule(GO:0042629)
0.3 4.7 GO:0030061 mitochondrial crista(GO:0030061)
0.3 24.0 GO:0031225 anchored component of membrane(GO:0031225)
0.3 16.2 GO:0031519 PcG protein complex(GO:0031519)
0.3 93.6 GO:0005759 mitochondrial matrix(GO:0005759)
0.3 20.0 GO:0045095 keratin filament(GO:0045095)
0.3 8.5 GO:0060077 inhibitory synapse(GO:0060077)
0.3 30.2 GO:0055037 recycling endosome(GO:0055037)
0.3 18.3 GO:0005811 lipid particle(GO:0005811)
0.3 34.1 GO:0005903 brush border(GO:0005903)
0.2 28.4 GO:0005923 bicellular tight junction(GO:0005923)
0.2 84.3 GO:0005667 transcription factor complex(GO:0005667)
0.2 5.5 GO:0000152 nuclear ubiquitin ligase complex(GO:0000152)
0.2 3.7 GO:0043296 apical junction complex(GO:0043296)
0.2 15.4 GO:0005604 basement membrane(GO:0005604)
0.2 1.4 GO:0031143 pseudopodium(GO:0031143)
0.1 19.3 GO:0016324 apical plasma membrane(GO:0016324)
0.1 50.8 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.1 21.7 GO:0019897 extrinsic component of plasma membrane(GO:0019897)
0.1 0.5 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 1.6 GO:0071564 npBAF complex(GO:0071564)
0.1 5.0 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 183.2 GO:0005783 endoplasmic reticulum(GO:0005783)
0.1 9.8 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.1 1.3 GO:0005771 multivesicular body(GO:0005771)
0.1 2.8 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.1 8.3 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 12.6 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.1 0.6 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 17.6 GO:0016607 nuclear speck(GO:0016607)
0.1 5.3 GO:0005938 cell cortex(GO:0005938)
0.1 10.4 GO:0031252 cell leading edge(GO:0031252)
0.0 1.2 GO:0034451 centriolar satellite(GO:0034451)
0.0 72.3 GO:0070062 extracellular exosome(GO:0070062)
0.0 2.4 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 2.7 GO:0036464 cytoplasmic ribonucleoprotein granule(GO:0036464)
0.0 13.7 GO:0005576 extracellular region(GO:0005576)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
17.7 53.0 GO:0004657 proline dehydrogenase activity(GO:0004657)
16.8 50.4 GO:0031714 C5a anaphylatoxin chemotactic receptor binding(GO:0031714)
12.2 60.8 GO:0008453 alanine-glyoxylate transaminase activity(GO:0008453)
11.4 34.2 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
7.9 63.5 GO:0016742 hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
7.8 38.8 GO:0004301 epoxide hydrolase activity(GO:0004301)
6.7 20.1 GO:0008405 arachidonic acid 11,12-epoxygenase activity(GO:0008405)
6.7 20.1 GO:0004736 pyruvate carboxylase activity(GO:0004736)
5.2 20.6 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
4.4 26.4 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
4.1 16.3 GO:0004594 pantothenate kinase activity(GO:0004594)
3.9 47.3 GO:0019864 IgG binding(GO:0019864)
3.8 19.1 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
3.7 11.2 GO:0004925 prolactin receptor activity(GO:0004925)
3.5 14.1 GO:0045159 myosin II binding(GO:0045159)
3.4 20.2 GO:0071723 beta-2-microglobulin binding(GO:0030881) lipopeptide binding(GO:0071723)
3.2 38.3 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
2.9 57.9 GO:0010181 FMN binding(GO:0010181)
2.7 16.2 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
2.5 12.4 GO:1990254 keratin filament binding(GO:1990254)
2.3 23.1 GO:0039706 co-receptor binding(GO:0039706)
2.3 6.9 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
2.3 13.8 GO:0004568 chitinase activity(GO:0004568)
2.3 9.1 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
2.2 13.4 GO:0070051 fibrinogen binding(GO:0070051)
2.2 25.9 GO:0019911 structural constituent of myelin sheath(GO:0019911)
2.1 16.7 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
2.0 16.2 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
1.8 21.7 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
1.7 10.5 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
1.7 39.8 GO:0015238 drug transmembrane transporter activity(GO:0015238)
1.6 4.8 GO:0008142 oxysterol binding(GO:0008142)
1.6 12.6 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
1.1 15.7 GO:0016500 protein-hormone receptor activity(GO:0016500)
1.1 32.9 GO:0015020 glucuronosyltransferase activity(GO:0015020)
1.1 4.2 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
1.1 10.5 GO:0019215 intermediate filament binding(GO:0019215)
0.9 5.6 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.9 2.7 GO:0004918 interleukin-8 receptor activity(GO:0004918)
0.9 12.8 GO:0016805 dipeptidase activity(GO:0016805)
0.9 105.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.9 3.6 GO:0019862 IgA binding(GO:0019862)
0.8 9.9 GO:0098879 structural constituent of postsynaptic specialization(GO:0098879) structural constituent of postsynaptic density(GO:0098919)
0.8 10.5 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.7 30.7 GO:0070330 aromatase activity(GO:0070330)
0.7 6.0 GO:0070697 activin receptor binding(GO:0070697)
0.7 5.6 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.7 4.7 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.6 14.3 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.6 5.8 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.6 20.9 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.6 13.0 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.6 7.3 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.6 10.8 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.6 28.8 GO:0005504 fatty acid binding(GO:0005504)
0.6 1.7 GO:0044715 8-oxo-dGDP phosphatase activity(GO:0044715)
0.6 5.6 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.5 1.6 GO:0042284 sphingolipid delta-4 desaturase activity(GO:0042284)
0.5 25.7 GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.5 3.9 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.5 11.1 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.5 8.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.4 2.2 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.4 24.4 GO:0035326 enhancer binding(GO:0035326)
0.4 12.0 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.4 13.5 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.4 5.7 GO:0042043 neurexin family protein binding(GO:0042043)
0.4 60.8 GO:0008083 growth factor activity(GO:0008083)
0.4 1.2 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.4 32.1 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.4 6.7 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.4 24.7 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.4 4.0 GO:0005346 adenine nucleotide transmembrane transporter activity(GO:0000295) purine ribonucleotide transmembrane transporter activity(GO:0005346)
0.3 36.5 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.3 1.3 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.3 5.6 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.3 40.3 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.3 4.6 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.3 50.1 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)
0.3 8.5 GO:0070840 dynein complex binding(GO:0070840)
0.3 7.0 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.3 3.3 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.3 19.4 GO:0005507 copper ion binding(GO:0005507)
0.3 16.8 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.3 38.3 GO:0003774 motor activity(GO:0003774)
0.3 11.7 GO:0016831 carboxy-lyase activity(GO:0016831)
0.3 1.3 GO:0070097 delta-catenin binding(GO:0070097)
0.3 7.6 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.2 23.2 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.2 1.9 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.2 5.1 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.2 7.3 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.2 2.6 GO:0004000 adenosine deaminase activity(GO:0004000)
0.2 7.9 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.2 23.2 GO:0008201 heparin binding(GO:0008201)
0.2 2.7 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.2 1.9 GO:0042056 chemoattractant activity(GO:0042056)
0.2 21.6 GO:0030674 protein binding, bridging(GO:0030674)
0.2 26.7 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.2 36.8 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.2 12.4 GO:0008013 beta-catenin binding(GO:0008013)
0.2 3.3 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.2 4.9 GO:0017075 syntaxin-1 binding(GO:0017075)
0.2 3.7 GO:0043014 alpha-tubulin binding(GO:0043014)
0.2 0.8 GO:0030280 structural constituent of epidermis(GO:0030280)
0.2 6.5 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.1 0.9 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.1 5.0 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.1 6.9 GO:0003727 single-stranded RNA binding(GO:0003727)
0.1 3.8 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.1 25.6 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.1 3.2 GO:0004707 MAP kinase activity(GO:0004707)
0.1 9.1 GO:0008565 protein transporter activity(GO:0008565)
0.1 1.2 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.1 0.6 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 17.4 GO:0008168 methyltransferase activity(GO:0008168)
0.1 5.1 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 3.4 GO:0001047 core promoter binding(GO:0001047)
0.1 12.2 GO:0008514 organic anion transmembrane transporter activity(GO:0008514)
0.1 1.4 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.1 0.5 GO:0050700 CARD domain binding(GO:0050700)
0.1 1.2 GO:0070063 RNA polymerase binding(GO:0070063)
0.1 1.9 GO:0019213 deacetylase activity(GO:0019213)
0.1 1.8 GO:0000049 tRNA binding(GO:0000049)
0.0 0.5 GO:0051400 BH domain binding(GO:0051400)
0.0 5.9 GO:0005179 hormone activity(GO:0005179)
0.0 3.5 GO:0020037 heme binding(GO:0020037)
0.0 0.5 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 10.8 GO:0016491 oxidoreductase activity(GO:0016491)
0.0 1.6 GO:0017137 Rab GTPase binding(GO:0017137)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 73.7 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
1.4 2.7 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
1.3 74.1 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
1.2 57.5 PID HNF3A PATHWAY FOXA1 transcription factor network
1.0 26.4 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.5 30.7 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.5 17.7 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.5 109.4 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.4 9.3 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.3 5.7 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.3 22.1 PID TGFBR PATHWAY TGF-beta receptor signaling
0.3 12.6 PID EPHA FWDPATHWAY EPHA forward signaling
0.3 8.6 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.3 11.2 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.3 10.6 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.3 7.1 PID NETRIN PATHWAY Netrin-mediated signaling events
0.3 5.3 PID IL3 PATHWAY IL3-mediated signaling events
0.3 44.3 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.2 2.8 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.2 20.7 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.2 5.1 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1 3.2 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.1 8.1 PID E2F PATHWAY E2F transcription factor network
0.1 3.7 PID RHOA PATHWAY RhoA signaling pathway
0.1 8.9 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.1 3.4 PID TELOMERASE PATHWAY Regulation of Telomerase
0.1 2.6 PID P73PATHWAY p73 transcription factor network
0.1 3.1 PID IL4 2PATHWAY IL4-mediated signaling events
0.1 3.4 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 2.0 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.6 PID CIRCADIAN PATHWAY Circadian rhythm pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
19.3 57.9 REACTOME XENOBIOTICS Genes involved in Xenobiotics
4.7 60.8 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
2.5 27.5 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
2.5 29.9 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
2.5 47.2 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
2.3 41.5 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
2.1 81.9 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
1.6 22.1 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
1.5 27.4 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
1.4 50.4 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
1.4 15.7 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
1.3 16.3 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
1.0 14.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.9 19.8 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.8 19.1 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.7 7.4 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.6 18.0 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.5 7.1 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.5 32.3 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.5 11.2 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.5 18.3 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.5 9.1 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.4 5.3 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.4 7.0 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.4 10.5 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.3 9.8 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.3 5.7 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF
0.3 41.3 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.3 16.0 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.3 3.2 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.3 7.7 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.3 3.8 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.3 5.1 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.2 6.7 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.2 10.8 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.2 6.8 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.2 37.2 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.2 5.6 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 1.4 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.1 2.2 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1 8.7 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 4.3 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 5.7 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.1 3.5 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 5.1 REACTOME SIGNALING BY SCF KIT Genes involved in Signaling by SCF-KIT
0.1 1.2 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.1 1.1 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 1.3 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 1.2 REACTOME ION CHANNEL TRANSPORT Genes involved in Ion channel transport
0.0 2.4 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.9 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.7 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation