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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Runx2_Bcl11a

Z-value: 2.63

Motif logo

Transcription factors associated with Runx2_Bcl11a

Gene Symbol Gene ID Gene Info
ENSRNOG00000020193 runt-related transcription factor 2
ENSRNOG00000007049 B-cell CLL/lymphoma 11A

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Runx2rn6_v1_chr9_+_18564927_185649270.502.0e-21Click!
Bcl11arn6_v1_chr14_+_108826831_1088269390.091.3e-01Click!

Activity profile of Runx2_Bcl11a motif

Sorted Z-values of Runx2_Bcl11a motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_206342066 127.91 ENSRNOT00000026556
protein tyrosine phosphatase, non-receptor type 22
chr15_+_32763067 117.83 ENSRNOT00000011998

chr3_+_19772056 107.96 ENSRNOT00000044455

chr10_-_70871066 107.30 ENSRNOT00000015139
C-C motif chemokine ligand 3
chr15_-_35417273 102.44 ENSRNOT00000083961
ENSRNOT00000041430
granzyme B
chr3_-_91217491 101.04 ENSRNOT00000006115
recombination activating 1
chr11_+_86092468 99.49 ENSRNOT00000057971
lambda-chain C1-region-like
chr4_+_70572942 99.37 ENSRNOT00000051964

chr3_+_18970574 90.25 ENSRNOT00000088394

chrX_-_71616997 87.74 ENSRNOT00000004406
C-X-C motif chemokine receptor 3
chr15_-_36472327 85.38 ENSRNOT00000032601
ENSRNOT00000059660
granzyme-like protein 1-like
chr1_+_219173002 82.32 ENSRNOT00000024018
unc-93 homolog B1 (C. elegans)
chr13_-_83202864 78.84 ENSRNOT00000003976
X-C motif chemokine ligand 1
chr18_-_28438654 78.80 ENSRNOT00000036301
marginal zone B and B1 cell-specific protein
chr10_-_94500591 78.80 ENSRNOT00000015976
CD79b molecule
chr5_-_58198782 78.64 ENSRNOT00000023951
C-C motif chemokine ligand 21
chr2_+_186703541 76.13 ENSRNOT00000093342
Fc receptor-like 1
chr15_-_36114752 75.85 ENSRNOT00000045209
Granzyme B-like 3
chr3_-_44177689 75.59 ENSRNOT00000006387
cytohesin 1 interacting protein
chr10_-_31493419 72.28 ENSRNOT00000009211
IL2-inducible T-cell kinase
chrX_+_15155230 70.14 ENSRNOT00000073289
ENSRNOT00000051439
Wiskott-Aldrich syndrome
chr10_-_56270640 69.34 ENSRNOT00000056918
Cd68 molecule
chr1_-_226887156 65.89 ENSRNOT00000054809
ENSRNOT00000028347
Cd6 molecule
chr15_-_34693034 65.19 ENSRNOT00000083314
mast cell protease 8
chr10_+_104952458 63.29 ENSRNOT00000074082
similar to immunoglobulin superfamily, member 7
chr1_+_216191886 62.24 ENSRNOT00000054863
tetraspanin 32
chr3_+_19045214 62.15 ENSRNOT00000070878

chr4_+_162541751 62.06 ENSRNOT00000010312
killer cell lectin-like receptor subfamily B member 1C
chr11_-_33003021 61.63 ENSRNOT00000084134
runt-related transcription factor 1
chr19_-_43911057 59.88 ENSRNOT00000026017
chymotrypsinogen B1
chr4_+_14212925 58.80 ENSRNOT00000076946
platelet glycoprotein 4-like
chr1_+_81230612 58.75 ENSRNOT00000026489
potassium calcium-activated channel subfamily N member 4
chr13_-_111917587 57.85 ENSRNOT00000007649
TRAF3 interacting protein 3
chr10_+_104997205 56.80 ENSRNOT00000074003
similar to dendritic cell-derived immunoglobulin(Ig)-like receptor 1, DIgR1 - mouse
chr4_+_78513459 56.48 ENSRNOT00000082905
amine oxidase, copper containing 1
chr11_+_57108956 55.60 ENSRNOT00000035485
CD96 molecule
chr4_-_155867708 55.51 ENSRNOT00000051525
C-type lectin domain family 4, member A2
chr3_-_6626284 53.26 ENSRNOT00000012494
ficolin B
chr20_-_5805627 52.95 ENSRNOT00000085996
colipase
chr12_-_20276121 52.85 ENSRNOT00000065873
similar to paired immunoglobin-like type 2 receptor beta
chr20_+_3156170 52.74 ENSRNOT00000082880
RT1 class Ib, locus S2
chr11_-_60547201 52.54 ENSRNOT00000093151
B and T lymphocyte associated
chr20_-_5806097 52.52 ENSRNOT00000000611
colipase
chr8_-_114617466 52.08 ENSRNOT00000082992
ENSRNOT00000038160
collagen type VI alpha 5 chain
chr15_-_34647421 51.14 ENSRNOT00000072426
mast cell protease 8
chr13_-_61591139 50.39 ENSRNOT00000005324
regulator of G-protein signaling 18
chr9_-_14668297 50.26 ENSRNOT00000042404
triggering receptor expressed on myeloid cells-like 2
chr10_-_19574094 49.76 ENSRNOT00000059810
dedicator of cytokinesis 2
chr4_-_157154120 49.53 ENSRNOT00000056058
complement C1s
chr4_-_162025090 49.51 ENSRNOT00000085887
ENSRNOT00000009904
killer cell lectin-like receptor subfamily B, member 1A
chr12_-_2245324 49.02 ENSRNOT00000001332
ENSRNOT00000001333
Fc fragment of IgE receptor II
chr6_-_138321002 47.79 ENSRNOT00000056845
immunoglobulin heavy constant mu
chr3_-_7141522 47.75 ENSRNOT00000014572
carboxyl ester lipase
chr3_-_46457201 47.18 ENSRNOT00000010683
lymphocyte antigen 75
chr9_+_18564927 45.98 ENSRNOT00000061014
runt-related transcription factor 2
chr1_-_98493978 45.57 ENSRNOT00000023942
natural killer cell granule protein 7
chr9_+_67546408 45.25 ENSRNOT00000013701
Cd28 molecule
chr4_+_66670618 44.82 ENSRNOT00000010796
thromboxane A synthase 1
chr11_-_60546997 44.46 ENSRNOT00000083124
ENSRNOT00000050092
B and T lymphocyte associated
chr3_+_19141133 43.95 ENSRNOT00000058323

chr3_+_19366370 43.80 ENSRNOT00000086557

chr11_+_84972132 43.58 ENSRNOT00000034498
lysosomal-associated membrane protein 3
chr10_+_104932616 43.20 ENSRNOT00000075706
similar to leukocyte mono-Ig-like receptor2
chr10_-_56506446 42.97 ENSRNOT00000021357
ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
chr7_-_12741296 42.83 ENSRNOT00000060648
Rho GTPase activating protein 45
chr3_+_18787606 42.69 ENSRNOT00000090508

chr6_-_142635763 42.63 ENSRNOT00000048908

chr20_-_21689553 42.55 ENSRNOT00000038095
transmembrane protein 26
chr6_-_139660666 42.45 ENSRNOT00000086098

chr1_+_88875375 42.23 ENSRNOT00000028284
Tyro protein tyrosine kinase binding protein
chr10_-_34242985 42.08 ENSRNOT00000046438
similar to novel protein
chr1_-_267463694 41.99 ENSRNOT00000084851
ENSRNOT00000016645
collagen type XVII alpha 1 chain
chr20_-_5076539 41.70 ENSRNOT00000076253
ENSRNOT00000037613
lymphocyte antigen 6 complex, locus G6F
chr6_-_143195445 40.72 ENSRNOT00000078672

chr4_+_119680112 40.60 ENSRNOT00000013282
glycoprotein IX (platelet)
chr2_-_149325913 40.59 ENSRNOT00000036690
G protein-coupled receptor 171
chr20_+_10438444 40.23 ENSRNOT00000071248
ENSRNOT00000075545
crystallin, alpha A
chr1_+_114046478 40.20 ENSRNOT00000032254
sialic acid binding Ig-like lectin H
chr1_+_199555722 39.82 ENSRNOT00000054983
integrin subunit alpha X
chr16_+_20110148 39.73 ENSRNOT00000080146
ENSRNOT00000025312
Janus kinase 3
chr16_+_20109200 39.00 ENSRNOT00000079784
Janus kinase 3
chr13_+_42008842 38.04 ENSRNOT00000038811
G protein-coupled receptor 39
chrX_+_14578264 37.86 ENSRNOT00000038994
cytochrome b-245 beta chain
chr10_+_15697227 37.56 ENSRNOT00000028008
interleukin 9 receptor
chr2_-_44981458 37.47 ENSRNOT00000014134
granzyme A
chr11_+_61970976 37.10 ENSRNOT00000078921
T cell immunoreceptor with Ig and ITIM domains
chr15_-_34625121 37.09 ENSRNOT00000073555
mast cell protease 8-like 2
chr15_-_34694180 37.07 ENSRNOT00000079505
ENSRNOT00000027950
ENSRNOT00000079782
ENSRNOT00000080221
mast cell protease 8
chr16_-_9430743 36.88 ENSRNOT00000043811
WDFY family member 4
chr13_-_90022269 36.62 ENSRNOT00000035498
lymphocyte antigen 9
chr2_+_55835151 36.22 ENSRNOT00000018634
FYN binding protein
chr7_-_12635943 36.21 ENSRNOT00000015029
complement factor D
chr1_+_81230989 35.75 ENSRNOT00000077952
potassium calcium-activated channel subfamily N member 4
chr16_+_10417185 35.48 ENSRNOT00000082186
annexin A8
chr15_-_28081465 34.91 ENSRNOT00000033739
ribonuclease, RNase A family, 6
chrX_-_159841072 34.72 ENSRNOT00000001158
Rac/Cdc42 guanine nucleotide exchange factor 6
chr1_+_101214593 34.23 ENSRNOT00000028086
TEA domain transcription factor 2
chr1_-_227506822 33.86 ENSRNOT00000091506
membrane spanning 4-domains A7
chr5_-_155772040 33.55 ENSRNOT00000036788
chymotrypsin-like elastase family, member 3B
chr6_-_142676432 33.46 ENSRNOT00000074947

chr6_-_142585188 33.43 ENSRNOT00000067437

chr15_+_35032049 33.17 ENSRNOT00000091757
mast cell protease 2
chr3_+_19441604 33.11 ENSRNOT00000090581

chr9_+_47165342 32.80 ENSRNOT00000020144
interleukin 1 receptor-like 1
chr10_+_59652549 32.27 ENSRNOT00000073209
integrin subunit alpha E
chr8_-_13251812 32.02 ENSRNOT00000049724
ENSRNOT00000078117
piwi-like RNA-mediated gene silencing 4
chr1_-_237910012 31.40 ENSRNOT00000023664
annexin A1
chr4_-_156276304 30.95 ENSRNOT00000078725
C-type lectin domain family 4, member E
chr13_+_51958834 30.78 ENSRNOT00000007833
protein tyrosine phosphatase, non-receptor type 7
chr1_-_82004538 30.65 ENSRNOT00000087572
POU class 2 homeobox 2
chr10_+_104952237 30.34 ENSRNOT00000085222
similar to immunoglobulin superfamily, member 7
chr4_-_119327822 30.30 ENSRNOT00000012645
Rho GTPase activating protein 25
chr4_+_119225040 30.12 ENSRNOT00000012365
bone morphogenetic protein 10
chr14_+_10692764 29.74 ENSRNOT00000003012
uncharacterized LOC100910270
chr12_-_21923281 29.63 ENSRNOT00000075641
similar to cell surface receptor FDFACT
chr15_-_51855325 29.37 ENSRNOT00000011663
PDZ and LIM domain 2
chr7_+_61337381 29.28 ENSRNOT00000009919
interferon gamma
chr2_-_203680083 29.12 ENSRNOT00000021268
Cd2 molecule
chr6_-_139911839 28.92 ENSRNOT00000077113
ENSRNOT00000084547

chr1_-_169456098 28.82 ENSRNOT00000030827
tripartite motif-containing 30C
chr8_+_2604962 28.66 ENSRNOT00000009993
caspase 1
chr13_+_88606894 28.64 ENSRNOT00000048692
SH2 domain containing 1B
chr4_-_70996395 28.24 ENSRNOT00000021485
Kell blood group, metallo-endopeptidase
chr2_-_198942732 27.97 ENSRNOT00000000109
ENSRNOT00000073913
CD160 molecule
chr4_+_69386698 27.53 ENSRNOT00000091655
T cell receptor beta, variable 13-2
chr12_-_21362205 27.46 ENSRNOT00000064787
paired immunoglobulin-like type 2 receptor beta-2
chr7_-_119797098 27.23 ENSRNOT00000009994
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr8_-_129371973 27.09 ENSRNOT00000042614
small nuclear ribonucleoprotein polypeptide E
chr15_-_34612432 27.02 ENSRNOT00000090206
mast cell protease 1-like 1
chr8_+_55603968 26.77 ENSRNOT00000066848
POU class 2 associating factor 1
chr1_-_167700332 26.73 ENSRNOT00000092890
tripartite motif-containing 21
chr11_+_88122271 26.58 ENSRNOT00000002540
stromal cell-derived factor 2-like 1
chr3_+_20007192 26.56 ENSRNOT00000075229

chr14_-_18853315 26.40 ENSRNOT00000003794
pro-platelet basic protein
chr16_-_75340360 26.32 ENSRNOT00000018501
defensin alpha 5
chr14_+_13192347 26.23 ENSRNOT00000000092
anthrax toxin receptor 2
chr20_+_30791422 26.22 ENSRNOT00000047394
ENSRNOT00000000683
thymus, brain and testes associated
chr17_-_32783427 26.14 ENSRNOT00000059921
serine (or cysteine) peptidase inhibitor, clade B, member 6b
chr3_+_17180411 25.70 ENSRNOT00000058260

chr9_+_67763897 25.68 ENSRNOT00000071226
inducible T-cell co-stimulator
chr1_-_173528943 25.58 ENSRNOT00000020393
NLR family, pyrin domain containing 10
chr4_+_14213587 25.33 ENSRNOT00000067543
platelet glycoprotein 4-like
chr18_-_28535828 25.29 ENSRNOT00000068386
transmembrane protein 173
chr3_+_18805220 25.19 ENSRNOT00000071216
immunoglobulin kappa variable 4-86
chr10_-_110701137 25.07 ENSRNOT00000074193
zinc finger protein 750
chr6_-_142933110 24.98 ENSRNOT00000046885

chr13_-_110784209 24.81 ENSRNOT00000071698
TNF receptor-associated factor 5
chr7_+_121841855 24.56 ENSRNOT00000024673
GRB2-related adaptor protein 2
chr1_+_63734135 24.48 ENSRNOT00000084439
neutrophil immunoglobulin-like receptor-1
chr1_+_31835000 24.30 ENSRNOT00000020780
centrosomal protein 72
chr10_-_89900131 23.76 ENSRNOT00000028238
sclerostin
chr14_-_100184192 23.72 ENSRNOT00000007044
pleckstrin
chr20_-_4316715 23.65 ENSRNOT00000031704
complement C4B (Chido blood group)
chr3_+_19128400 23.54 ENSRNOT00000074272

chr20_-_4508197 23.44 ENSRNOT00000086027
ENSRNOT00000000514
complement component 4A (Rodgers blood group)
chr4_-_164049599 23.40 ENSRNOT00000078267

chr20_-_2678141 23.10 ENSRNOT00000072377
ENSRNOT00000083833
complement component 4A (Rodgers blood group)
chr1_+_165506361 23.02 ENSRNOT00000024156
uncoupling protein 2
chr1_-_198662610 22.95 ENSRNOT00000055012
septin 1
chr14_-_5378726 22.92 ENSRNOT00000002896
leucine rich repeat containing 8 family, member C
chr6_-_107658741 22.74 ENSRNOT00000088712
ELM2 and Myb/SANT domain containing 1
chr4_-_165541314 22.42 ENSRNOT00000013833
serine/threonine/tyrosine kinase 1
chr1_-_169463760 22.41 ENSRNOT00000023100
tripartite motif-containing 30C
chr7_-_144880092 22.40 ENSRNOT00000055281
nuclear factor, erythroid 2
chr14_-_22890958 22.22 ENSRNOT00000031916
lymphocyte antigen 6B-like
chr1_+_197999037 22.13 ENSRNOT00000091065
apolipoprotein B receptor
chr11_+_71211768 21.90 ENSRNOT00000079753
uncharacterized LOC100910650
chr10_-_57436368 21.64 ENSRNOT00000056608
SLP adaptor and CSK interacting membrane protein
chr10_+_45258887 21.63 ENSRNOT00000048642
butyrophilin like 10
chr10_+_1406486 21.58 ENSRNOT00000078773
similar to dynein, cytoplasmic, light peptide
chr3_+_20303979 21.57 ENSRNOT00000058331

chr3_-_92749121 21.49 ENSRNOT00000008760
CD44 molecule (Indian blood group)
chr4_+_57855416 21.42 ENSRNOT00000029608
carboxypeptidase A2
chr12_+_21678580 21.37 ENSRNOT00000039797
paired immunoglobulin-like type 2 receptor alpha-like
chr3_+_20375699 21.31 ENSRNOT00000088492

chr20_-_4561062 21.20 ENSRNOT00000065044
ENSRNOT00000092698
ENSRNOT00000060607
complement factor B
complement C2
chr18_-_27520295 21.18 ENSRNOT00000027544
GDNF family receptor alpha 3
chr11_+_84506703 21.13 ENSRNOT00000066953
cytochrome P450, family 2, subfamily ab, polypeptide 1
chr8_-_69121192 21.04 ENSRNOT00000012404
zwilch kinetochore protein
chrX_-_62661152 20.94 ENSRNOT00000075997
DNA polymerase alpha 1, catalytic subunit
chr10_+_69423086 20.90 ENSRNOT00000000256
C-C motif chemokine ligand 7
chr1_-_259357056 20.80 ENSRNOT00000022000
PDZ and LIM domain 1
chr10_-_86930947 20.74 ENSRNOT00000081440
topoisomerase (DNA) II alpha
chr13_+_92249759 20.49 ENSRNOT00000089352
olfactory receptor 1596
chr8_-_133002201 20.45 ENSRNOT00000008772
C-C motif chemokine receptor 1
chr2_+_87418517 20.42 ENSRNOT00000048046
tyrosine-protein phosphatase non-receptor type substrate 1-like
chr10_-_5253336 20.41 ENSRNOT00000085310
class II, major histocompatibility complex, transactivator
chr5_-_160405050 20.40 ENSRNOT00000081899
chymotrypsin C
chr1_+_98398660 20.32 ENSRNOT00000047473
CD33 molecule
chr13_-_61070599 20.30 ENSRNOT00000005251
regulator of G-protein signaling 1
chr5_+_64566804 20.29 ENSRNOT00000073192
TGF-beta receptor type-1-like
chr5_+_151181559 20.27 ENSRNOT00000085674
FGR proto-oncogene, Src family tyrosine kinase
chr1_+_196996581 20.27 ENSRNOT00000021690
interleukin 21 receptor
chr1_-_85220237 20.21 ENSRNOT00000026907
syncollin
chr13_-_36101411 20.07 ENSRNOT00000074471
transmembrane protein 37
chr15_+_31719866 20.03 ENSRNOT00000072127

chr13_+_27465930 19.90 ENSRNOT00000003314
serpin family B member 10
chr3_-_153250641 19.72 ENSRNOT00000008961
SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1
chr14_+_33010300 19.63 ENSRNOT00000002809
insulin-like growth factor binding protein 7
chrX_+_156873849 19.60 ENSRNOT00000085410
Rho GTPase activating protein 4

Network of associatons between targets according to the STRING database.

First level regulatory network of Runx2_Bcl11a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
68.9 206.7 GO:0071663 granzyme B production(GO:0071613) regulation of granzyme B production(GO:0071661) positive regulation of granzyme B production(GO:0071663)
34.1 102.4 GO:0060545 positive regulation of necroptotic process(GO:0060545)
26.2 78.7 GO:0045210 negative regulation of dendritic cell cytokine production(GO:0002731) FasL biosynthetic process(GO:0045210)
26.2 78.6 GO:0035759 mesangial cell-matrix adhesion(GO:0035759)
25.6 128.2 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
25.3 101.0 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
20.5 61.6 GO:2000872 positive regulation of progesterone secretion(GO:2000872)
19.7 78.8 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
16.6 49.8 GO:0002277 myeloid dendritic cell activation involved in immune response(GO:0002277)
16.5 82.3 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
15.6 62.2 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
15.2 45.6 GO:0002380 immunoglobulin secretion involved in immune response(GO:0002380)
13.3 53.3 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
12.7 38.0 GO:0035483 gastric emptying(GO:0035483)
12.6 37.9 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
12.3 49.0 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
11.8 118.5 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
11.7 70.1 GO:0002457 T cell antigen processing and presentation(GO:0002457)
11.7 46.7 GO:0046061 dATP catabolic process(GO:0046061)
10.9 32.8 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
10.7 21.4 GO:0002876 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874) positive regulation of chronic inflammatory response to antigenic stimulus(GO:0002876)
9.8 29.3 GO:0060559 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
9.6 95.7 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
9.6 66.9 GO:0032429 regulation of phospholipase A2 activity(GO:0032429)
8.4 41.8 GO:0071104 response to interleukin-9(GO:0071104)
8.1 24.3 GO:0033566 gamma-tubulin complex localization(GO:0033566)
7.9 55.6 GO:0002727 natural killer cell cytokine production(GO:0002370) regulation of natural killer cell cytokine production(GO:0002727)
7.9 23.8 GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
7.7 46.0 GO:0002051 osteoblast fate commitment(GO:0002051)
7.7 23.0 GO:0007056 spindle assembly involved in female meiosis(GO:0007056)
7.4 110.3 GO:0001771 immunological synapse formation(GO:0001771)
7.2 28.7 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
6.9 20.7 GO:0010752 regulation of cGMP-mediated signaling(GO:0010752)
6.9 13.8 GO:2000422 regulation of eosinophil chemotaxis(GO:2000422) positive regulation of eosinophil chemotaxis(GO:2000424)
6.9 27.5 GO:2000318 positive regulation of T-helper 17 type immune response(GO:2000318)
6.7 40.2 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
6.7 93.8 GO:1900118 negative regulation of execution phase of apoptosis(GO:1900118)
6.6 72.3 GO:0001865 NK T cell differentiation(GO:0001865)
6.2 37.5 GO:0032074 negative regulation of nuclease activity(GO:0032074)
6.1 18.3 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
5.9 23.7 GO:0070560 protein secretion by platelet(GO:0070560)
5.6 44.8 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
5.5 22.2 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
5.3 15.9 GO:2001226 negative regulation of inorganic anion transmembrane transport(GO:1903796) negative regulation of chloride transport(GO:2001226)
5.2 20.9 GO:0006272 leading strand elongation(GO:0006272)
5.2 36.6 GO:0032740 positive regulation of interleukin-17 production(GO:0032740)
5.2 15.6 GO:0019303 D-ribose catabolic process(GO:0019303)
5.2 15.6 GO:1990868 response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869)
5.0 55.5 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
5.0 15.0 GO:0055073 cadmium ion homeostasis(GO:0055073)
5.0 44.8 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
4.7 28.2 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
4.7 42.2 GO:2001204 regulation of osteoclast development(GO:2001204)
4.7 14.0 GO:0042125 protein glycosylation at cell surface(GO:0033575) protein galactosylation at cell surface(GO:0033580) protein galactosylation(GO:0042125)
4.6 18.5 GO:0010999 regulation of eIF2 alpha phosphorylation by heme(GO:0010999)
4.6 32.0 GO:0010528 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
4.4 13.3 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
4.4 13.3 GO:0002414 immunoglobulin transcytosis in epithelial cells(GO:0002414)
4.3 8.6 GO:0033668 negative regulation by symbiont of host apoptotic process(GO:0033668) negative regulation by symbiont of host programmed cell death(GO:0052041) negative regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052490)
4.3 25.7 GO:0030263 apoptotic chromosome condensation(GO:0030263)
4.2 4.2 GO:0039530 MDA-5 signaling pathway(GO:0039530)
4.2 29.1 GO:2000484 positive regulation of interleukin-8 secretion(GO:2000484)
4.1 8.3 GO:0034163 regulation of toll-like receptor 9 signaling pathway(GO:0034163)
4.1 12.3 GO:0018199 peptidyl-glutamine modification(GO:0018199)
4.1 16.4 GO:0002884 negative regulation of hypersensitivity(GO:0002884)
4.0 11.9 GO:0001788 antibody-dependent cellular cytotoxicity(GO:0001788)
3.9 47.2 GO:0001867 complement activation, lectin pathway(GO:0001867)
3.9 11.8 GO:0035964 COPI-coated vesicle budding(GO:0035964)
3.9 27.2 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)
3.9 19.3 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
3.8 34.5 GO:0006957 complement activation, alternative pathway(GO:0006957)
3.8 15.2 GO:1903575 cornified envelope assembly(GO:1903575)
3.7 47.8 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
3.6 18.2 GO:0072564 blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
3.4 10.3 GO:0042222 interleukin-1 biosynthetic process(GO:0042222)
3.4 20.4 GO:0045341 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343) positive regulation of MHC class I biosynthetic process(GO:0045345)
3.4 20.3 GO:0061737 leukotriene signaling pathway(GO:0061737)
3.4 10.1 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
3.3 6.7 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
3.3 10.0 GO:1901674 histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674)
3.3 9.8 GO:0002148 hypochlorous acid metabolic process(GO:0002148) hypochlorous acid biosynthetic process(GO:0002149)
3.2 6.3 GO:0098758 response to interleukin-8(GO:0098758) cellular response to interleukin-8(GO:0098759)
3.2 12.6 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
3.2 37.9 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
3.2 12.6 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534) positive regulation of MDA-5 signaling pathway(GO:1900245)
3.1 12.4 GO:0051106 regulation of DNA ligation(GO:0051105) positive regulation of DNA ligation(GO:0051106)
3.1 9.2 GO:0006529 asparagine biosynthetic process(GO:0006529)
3.0 21.3 GO:0003057 regulation of the force of heart contraction by chemical signal(GO:0003057)
3.0 39.5 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
3.0 27.1 GO:0052697 xenobiotic glucuronidation(GO:0052697)
3.0 9.0 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
3.0 54.0 GO:0006958 complement activation, classical pathway(GO:0006958)
3.0 6.0 GO:1904124 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
3.0 5.9 GO:0071930 negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
3.0 11.9 GO:0034421 post-translational protein acetylation(GO:0034421)
3.0 8.9 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
2.9 14.6 GO:0001574 ganglioside biosynthetic process(GO:0001574)
2.9 31.8 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
2.8 56.5 GO:0071280 cellular response to copper ion(GO:0071280)
2.8 8.4 GO:0045077 peripheral T cell tolerance induction(GO:0002458) peripheral tolerance induction(GO:0002465) negative regulation of interferon-gamma biosynthetic process(GO:0045077)
2.8 8.4 GO:0070638 nicotinamide riboside catabolic process(GO:0006738) nicotinamide riboside metabolic process(GO:0046495) pyridine nucleoside metabolic process(GO:0070637) pyridine nucleoside catabolic process(GO:0070638)
2.8 19.3 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773)
2.7 8.1 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
2.7 13.5 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
2.7 8.0 GO:1903898 cap-dependent translational initiation(GO:0002191) positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493) negative regulation of PERK-mediated unfolded protein response(GO:1903898)
2.7 26.6 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
2.7 13.3 GO:0010032 meiotic chromosome condensation(GO:0010032)
2.6 37.1 GO:0032695 negative regulation of interleukin-12 production(GO:0032695)
2.6 7.9 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
2.6 15.7 GO:0060700 regulation of ribonuclease activity(GO:0060700)
2.6 10.5 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352) positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
2.6 7.8 GO:0060697 positive regulation of phospholipid catabolic process(GO:0060697)
2.6 10.4 GO:0090290 positive regulation of natural killer cell proliferation(GO:0032819) positive regulation of osteoclast proliferation(GO:0090290)
2.6 7.8 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
2.6 5.1 GO:0045626 negative regulation of T-helper 1 cell differentiation(GO:0045626)
2.6 5.1 GO:0032752 regulation of interleukin-3 production(GO:0032672) positive regulation of interleukin-3 production(GO:0032752) interleukin-3 biosynthetic process(GO:0042223) regulation of interleukin-3 biosynthetic process(GO:0045399) positive regulation of interleukin-3 biosynthetic process(GO:0045401) positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425)
2.5 17.7 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
2.5 25.3 GO:0071360 cellular response to exogenous dsRNA(GO:0071360)
2.5 9.9 GO:0055099 regulation of Cdc42 protein signal transduction(GO:0032489) response to high density lipoprotein particle(GO:0055099) platelet dense granule organization(GO:0060155)
2.4 26.6 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
2.4 48.2 GO:0030502 negative regulation of bone mineralization(GO:0030502)
2.4 33.6 GO:1990845 adaptive thermogenesis(GO:1990845)
2.4 30.9 GO:0038094 Fc-gamma receptor signaling pathway(GO:0038094)
2.4 4.7 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
2.4 18.9 GO:0034214 protein hexamerization(GO:0034214)
2.3 9.4 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
2.3 11.5 GO:0006287 base-excision repair, gap-filling(GO:0006287)
2.3 29.7 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
2.3 20.3 GO:0010759 positive regulation of macrophage chemotaxis(GO:0010759)
2.2 143.8 GO:0032094 response to food(GO:0032094)
2.2 19.6 GO:0051414 response to cortisol(GO:0051414)
2.2 8.7 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
2.1 6.4 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
2.1 19.0 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
2.1 8.4 GO:0002536 respiratory burst involved in inflammatory response(GO:0002536)
2.1 39.9 GO:0031581 hemidesmosome assembly(GO:0031581)
2.1 21.0 GO:0002517 T cell tolerance induction(GO:0002517)
2.1 10.5 GO:0072366 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter(GO:0072366)
2.1 8.4 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
2.0 10.2 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
2.0 12.2 GO:0010572 positive regulation of platelet activation(GO:0010572)
2.0 6.1 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
2.0 32.4 GO:0048368 lateral mesoderm development(GO:0048368)
2.0 9.9 GO:0002786 regulation of antimicrobial peptide production(GO:0002784) regulation of antibacterial peptide production(GO:0002786)
2.0 11.9 GO:0072615 interleukin-17 secretion(GO:0072615)
2.0 13.7 GO:0010764 negative regulation of fibroblast migration(GO:0010764)
1.9 13.6 GO:0002507 tolerance induction(GO:0002507)
1.9 5.7 GO:0070495 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
1.9 3.8 GO:0002589 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589)
1.9 7.5 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
1.8 5.5 GO:1900111 positive regulation of histone H3-K9 dimethylation(GO:1900111) positive regulation of histone H3-K9 trimethylation(GO:1900114)
1.8 5.5 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
1.8 14.6 GO:0002283 neutrophil activation involved in immune response(GO:0002283)
1.8 3.7 GO:0032902 nerve growth factor production(GO:0032902)
1.8 14.6 GO:0060481 lobar bronchus epithelium development(GO:0060481)
1.8 52.8 GO:0035455 response to interferon-alpha(GO:0035455)
1.8 14.5 GO:0042795 snRNA transcription from RNA polymerase II promoter(GO:0042795)
1.8 57.7 GO:0035456 response to interferon-beta(GO:0035456)
1.8 5.3 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
1.8 19.3 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
1.8 5.3 GO:0046333 octopamine biosynthetic process(GO:0006589) octopamine metabolic process(GO:0046333)
1.7 5.1 GO:0009644 response to high light intensity(GO:0009644)
1.7 5.1 GO:0070634 transepithelial ammonium transport(GO:0070634)
1.7 5.1 GO:1904976 cellular response to bleomycin(GO:1904976)
1.7 73.6 GO:0050853 B cell receptor signaling pathway(GO:0050853)
1.7 5.0 GO:0032907 transforming growth factor beta3 production(GO:0032907) regulation of transforming growth factor beta3 production(GO:0032910) positive regulation of transforming growth factor beta3 production(GO:0032916)
1.6 26.3 GO:0031640 killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364)
1.6 6.5 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
1.6 6.5 GO:0032627 interleukin-23 production(GO:0032627) regulation of interleukin-23 production(GO:0032667) negative regulation of interleukin-23 production(GO:0032707)
1.6 6.3 GO:0071718 sodium-independent icosanoid transport(GO:0071718)
1.6 9.5 GO:0030916 otic vesicle formation(GO:0030916)
1.5 6.2 GO:0061073 ciliary body morphogenesis(GO:0061073)
1.5 3.1 GO:0090579 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
1.5 12.0 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
1.5 7.5 GO:0002920 regulation of humoral immune response(GO:0002920)
1.5 5.9 GO:0023021 termination of signal transduction(GO:0023021)
1.5 24.9 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
1.4 7.2 GO:0006787 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
1.4 5.8 GO:1902608 regulation of large conductance calcium-activated potassium channel activity(GO:1902606) positive regulation of large conductance calcium-activated potassium channel activity(GO:1902608)
1.4 7.2 GO:0042535 positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
1.4 8.6 GO:0060263 regulation of respiratory burst(GO:0060263)
1.4 7.0 GO:0035617 stress granule disassembly(GO:0035617)
1.4 15.2 GO:0042738 exogenous drug catabolic process(GO:0042738)
1.4 4.1 GO:0021678 third ventricle development(GO:0021678)
1.3 2.6 GO:0060838 lymphatic endothelial cell fate commitment(GO:0060838) regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
1.3 10.5 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
1.3 5.1 GO:0060744 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
1.3 15.2 GO:0046485 ether lipid metabolic process(GO:0046485)
1.3 7.6 GO:0033567 DNA replication, Okazaki fragment processing(GO:0033567)
1.3 360.4 GO:0016485 protein processing(GO:0016485)
1.3 7.5 GO:0061052 negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
1.3 23.8 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
1.2 8.7 GO:0034625 fatty acid elongation, monounsaturated fatty acid(GO:0034625)
1.2 37.3 GO:0033006 regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304)
1.2 10.8 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
1.2 3.5 GO:1901844 regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844)
1.2 8.2 GO:0035878 nail development(GO:0035878)
1.1 3.4 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
1.1 6.7 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
1.1 22.0 GO:0097320 membrane tubulation(GO:0097320)
1.1 6.5 GO:0048478 replication fork protection(GO:0048478)
1.1 4.3 GO:0009115 xanthine catabolic process(GO:0009115) xanthine metabolic process(GO:0046110)
1.1 7.4 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
1.1 5.3 GO:1901724 miRNA catabolic process(GO:0010587) positive regulation of cell proliferation involved in kidney development(GO:1901724)
1.1 83.2 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
1.1 3.2 GO:0060490 serotonergic neuron axon guidance(GO:0036515) dichotomous subdivision of terminal units involved in lung branching(GO:0060448) orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
1.0 9.4 GO:0085020 protein K6-linked ubiquitination(GO:0085020)
1.0 11.5 GO:1902255 positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
1.0 3.1 GO:0060295 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019) positive regulation of feeding behavior(GO:2000253)
1.0 6.1 GO:0015677 copper ion import(GO:0015677)
1.0 5.0 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
1.0 7.0 GO:0051451 myoblast migration(GO:0051451)
1.0 15.9 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
1.0 4.0 GO:0009597 detection of virus(GO:0009597)
1.0 21.2 GO:0048485 sympathetic nervous system development(GO:0048485)
0.9 2.8 GO:0033505 floor plate formation(GO:0021508) floor plate morphogenesis(GO:0033505)
0.9 19.7 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.9 3.7 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
0.9 2.7 GO:0071461 cellular response to redox state(GO:0071461)
0.9 8.1 GO:0035814 negative regulation of renal sodium excretion(GO:0035814)
0.9 13.3 GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
0.9 2.6 GO:0016240 autophagosome docking(GO:0016240)
0.9 4.3 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.9 1.7 GO:0030969 mRNA splicing via endonucleolytic cleavage and ligation involved in unfolded protein response(GO:0030969) mRNA splicing, via endonucleolytic cleavage and ligation(GO:0070054) mRNA endonucleolytic cleavage involved in unfolded protein response(GO:0070055)
0.9 24.9 GO:0045576 mast cell activation(GO:0045576)
0.9 6.8 GO:0016266 O-glycan processing(GO:0016266)
0.8 4.2 GO:1900034 regulation of cellular response to heat(GO:1900034)
0.8 5.8 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.8 13.9 GO:0030574 collagen catabolic process(GO:0030574)
0.8 2.4 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.8 17.4 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.8 34.7 GO:0030032 lamellipodium assembly(GO:0030032)
0.8 12.6 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.8 3.2 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.8 3.1 GO:0070366 regulation of hepatocyte differentiation(GO:0070366)
0.8 27.1 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.8 10.8 GO:0042118 endothelial cell activation(GO:0042118)
0.8 6.2 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.8 6.1 GO:0019388 galactose catabolic process(GO:0019388)
0.8 4.6 GO:1900115 extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.7 8.2 GO:0045779 negative regulation of bone resorption(GO:0045779)
0.7 12.7 GO:0002716 negative regulation of natural killer cell mediated immunity(GO:0002716)
0.7 3.7 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.7 1.5 GO:0097037 heme export(GO:0097037)
0.7 17.0 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.7 21.0 GO:0018149 peptide cross-linking(GO:0018149)
0.7 2.1 GO:0021569 rhombomere 3 development(GO:0021569)
0.7 3.4 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.7 10.6 GO:0042573 retinoic acid metabolic process(GO:0042573)
0.7 3.3 GO:0038203 TORC2 signaling(GO:0038203)
0.7 7.3 GO:1901299 negative regulation of hydrogen peroxide-mediated programmed cell death(GO:1901299)
0.7 2.6 GO:0032620 interleukin-17 production(GO:0032620)
0.7 9.8 GO:0043129 surfactant homeostasis(GO:0043129)
0.6 5.8 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.6 8.9 GO:0035066 positive regulation of histone acetylation(GO:0035066)
0.6 6.4 GO:0051382 kinetochore assembly(GO:0051382)
0.6 1.3 GO:1900368 regulation of RNA interference(GO:1900368)
0.6 18.2 GO:0060325 face morphogenesis(GO:0060325)
0.6 14.4 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.6 2.5 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
0.6 12.1 GO:0032611 interleukin-1 beta production(GO:0032611)
0.6 3.5 GO:0090367 negative regulation of mRNA modification(GO:0090367)
0.6 10.8 GO:0016180 snRNA processing(GO:0016180)
0.6 2.8 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.6 5.5 GO:0040018 positive regulation of multicellular organism growth(GO:0040018)
0.5 10.9 GO:0002115 store-operated calcium entry(GO:0002115)
0.5 2.2 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.5 3.2 GO:1990573 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914) potassium ion import across plasma membrane(GO:1990573)
0.5 4.2 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.5 2.1 GO:2000348 protein linear polyubiquitination(GO:0097039) regulation of CD40 signaling pathway(GO:2000348)
0.5 2.6 GO:0006751 glutathione catabolic process(GO:0006751)
0.5 1.5 GO:0097167 circadian regulation of translation(GO:0097167)
0.5 10.7 GO:0002548 monocyte chemotaxis(GO:0002548)
0.5 1.0 GO:0048298 immunoglobulin production in mucosal tissue(GO:0002426) positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.5 16.7 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.5 4.5 GO:0046549 photoreceptor cell outer segment organization(GO:0035845) retinal rod cell development(GO:0046548) retinal cone cell development(GO:0046549)
0.5 2.5 GO:0034627 'de novo' NAD biosynthetic process(GO:0034627)
0.5 7.2 GO:0032674 regulation of interleukin-5 production(GO:0032674)
0.5 11.9 GO:0060512 prostate gland morphogenesis(GO:0060512)
0.5 4.7 GO:0038180 nerve growth factor signaling pathway(GO:0038180)
0.5 3.6 GO:0090179 planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.5 7.7 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.4 11.6 GO:0060009 Sertoli cell development(GO:0060009)
0.4 29.3 GO:0045766 positive regulation of angiogenesis(GO:0045766)
0.4 19.2 GO:1901998 toxin transport(GO:1901998)
0.4 35.3 GO:0019882 antigen processing and presentation(GO:0019882)
0.4 1.3 GO:0097681 base-excision repair, DNA ligation(GO:0006288) double-strand break repair via alternative nonhomologous end joining(GO:0097681)
0.4 2.6 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.4 5.9 GO:0042100 B cell proliferation(GO:0042100)
0.4 5.0 GO:0035278 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.4 10.0 GO:0045475 locomotor rhythm(GO:0045475)
0.4 2.5 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.4 1.2 GO:0060903 positive regulation of meiosis I(GO:0060903)
0.4 1.2 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.4 2.8 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.4 3.2 GO:0010586 miRNA metabolic process(GO:0010586)
0.4 1.2 GO:0097298 regulation of nucleus size(GO:0097298)
0.4 2.7 GO:0002934 desmosome organization(GO:0002934)
0.4 3.1 GO:1901550 regulation of endothelial cell development(GO:1901550) regulation of establishment of endothelial barrier(GO:1903140)
0.4 28.1 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.4 4.5 GO:0006108 malate metabolic process(GO:0006108)
0.4 2.6 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.4 1.1 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.4 45.6 GO:0090501 RNA phosphodiester bond hydrolysis(GO:0090501)
0.4 3.6 GO:2000010 positive regulation of protein localization to cell surface(GO:2000010)
0.4 13.3 GO:0002250 adaptive immune response(GO:0002250)
0.4 5.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.4 12.3 GO:0035904 aorta development(GO:0035904)
0.3 1.7 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.3 2.4 GO:0060837 blood vessel endothelial cell differentiation(GO:0060837)
0.3 3.8 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.3 9.3 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.3 3.1 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.3 1.6 GO:0007207 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.3 1.0 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023)
0.3 5.7 GO:0030199 collagen fibril organization(GO:0030199)
0.3 1.3 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.3 1.9 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.3 6.1 GO:0046037 GMP metabolic process(GO:0046037)
0.3 1.2 GO:0071376 response to corticotropin-releasing hormone(GO:0043435) general adaptation syndrome(GO:0051866) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.3 0.9 GO:0035522 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.3 1.8 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.3 4.7 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.3 1.7 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.3 1.4 GO:0046628 positive regulation of insulin receptor signaling pathway(GO:0046628)
0.3 23.6 GO:0006342 chromatin silencing(GO:0006342)
0.3 9.0 GO:2000036 regulation of stem cell population maintenance(GO:2000036)
0.3 4.4 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.3 4.4 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.3 2.4 GO:0045616 regulation of keratinocyte differentiation(GO:0045616)
0.3 1.3 GO:0042976 activation of Janus kinase activity(GO:0042976)
0.3 2.0 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.2 5.4 GO:0045109 intermediate filament organization(GO:0045109)
0.2 9.0 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.2 2.1 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.2 0.7 GO:1902416 positive regulation of mRNA binding(GO:1902416) positive regulation of RNA binding(GO:1905216)
0.2 1.6 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.2 3.0 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.2 1.4 GO:0032486 Rap protein signal transduction(GO:0032486)
0.2 14.2 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.2 1.1 GO:0009732 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.2 4.5 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.2 11.7 GO:0045454 cell redox homeostasis(GO:0045454)
0.2 7.7 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.2 2.4 GO:0034063 stress granule assembly(GO:0034063)
0.2 1.1 GO:1903392 negative regulation of focal adhesion assembly(GO:0051895) negative regulation of adherens junction organization(GO:1903392)
0.2 7.5 GO:0050715 positive regulation of cytokine secretion(GO:0050715)
0.2 12.2 GO:0000045 autophagosome assembly(GO:0000045)
0.2 10.7 GO:0002181 cytoplasmic translation(GO:0002181)
0.2 8.8 GO:0015804 neutral amino acid transport(GO:0015804)
0.2 3.6 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.2 38.3 GO:0006898 receptor-mediated endocytosis(GO:0006898)
0.2 7.0 GO:0097421 liver regeneration(GO:0097421)
0.2 7.5 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.2 39.0 GO:0042110 T cell activation(GO:0042110) T cell aggregation(GO:0070489)
0.2 11.2 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.2 0.6 GO:0060965 negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967) negative regulation of gene silencing(GO:0060969)
0.2 16.8 GO:0009615 response to virus(GO:0009615)
0.2 5.8 GO:0048146 positive regulation of fibroblast proliferation(GO:0048146)
0.2 1.5 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.2 13.6 GO:0008203 cholesterol metabolic process(GO:0008203)
0.2 1.4 GO:0070986 left/right axis specification(GO:0070986)
0.2 6.9 GO:0030819 positive regulation of cAMP biosynthetic process(GO:0030819)
0.2 6.5 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.2 0.9 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.2 1.1 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.2 3.5 GO:0046825 regulation of protein export from nucleus(GO:0046825)
0.2 48.9 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway(GO:0007169)
0.2 2.1 GO:0007625 grooming behavior(GO:0007625)
0.2 0.6 GO:0043101 purine-containing compound salvage(GO:0043101)
0.2 3.5 GO:0009303 rRNA transcription(GO:0009303)
0.1 7.5 GO:0006414 translational elongation(GO:0006414)
0.1 1.8 GO:0019835 cytolysis(GO:0019835)
0.1 1.0 GO:0046579 positive regulation of Ras protein signal transduction(GO:0046579)
0.1 3.1 GO:0006284 base-excision repair(GO:0006284)
0.1 0.2 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747)
0.1 6.6 GO:0060349 bone morphogenesis(GO:0060349)
0.1 4.7 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 1.5 GO:0009086 methionine biosynthetic process(GO:0009086)
0.1 0.3 GO:1904781 positive regulation of protein localization to centrosome(GO:1904781)
0.1 1.5 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.1 5.7 GO:0001895 retina homeostasis(GO:0001895)
0.1 1.6 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.1 0.4 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 0.5 GO:0061526 acetylcholine secretion(GO:0061526)
0.1 0.3 GO:0090241 negative regulation of histone H4 acetylation(GO:0090241)
0.1 2.5 GO:0043507 positive regulation of JUN kinase activity(GO:0043507)
0.1 2.6 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.1 0.7 GO:0001887 selenium compound metabolic process(GO:0001887)
0.1 7.3 GO:0007059 chromosome segregation(GO:0007059)
0.1 0.4 GO:0021516 dorsal spinal cord development(GO:0021516)
0.1 3.3 GO:0051703 social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.1 1.3 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.1 2.3 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.1 2.5 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.1 3.5 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.1 1.6 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.1 1.1 GO:0000187 activation of MAPK activity(GO:0000187)
0.1 2.5 GO:0051298 centrosome duplication(GO:0051298)
0.1 0.2 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.1 0.3 GO:0046532 regulation of photoreceptor cell differentiation(GO:0046532)
0.1 0.4 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.1 1.5 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123) DNA-templated transcriptional preinitiation complex assembly(GO:0070897)
0.1 2.8 GO:0006400 tRNA modification(GO:0006400)
0.1 1.0 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.1 3.4 GO:0007088 regulation of mitotic nuclear division(GO:0007088)
0.0 0.2 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0 0.5 GO:0045672 positive regulation of osteoclast differentiation(GO:0045672)
0.0 0.3 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 2.7 GO:0000724 double-strand break repair via homologous recombination(GO:0000724)
0.0 2.1 GO:0051028 mRNA transport(GO:0051028)
0.0 0.3 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.3 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.6 GO:0061053 somite development(GO:0061053)
0.0 0.7 GO:0090305 nucleic acid phosphodiester bond hydrolysis(GO:0090305)
0.0 0.1 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.1 GO:0001573 ganglioside metabolic process(GO:0001573)
0.0 0.9 GO:0007127 meiosis I(GO:0007127)
0.0 0.3 GO:0046676 negative regulation of insulin secretion(GO:0046676)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
22.0 65.9 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
19.7 78.8 GO:0019815 B cell receptor complex(GO:0019815)
14.5 43.6 GO:0097233 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
13.5 107.7 GO:0044194 cytolytic granule(GO:0044194)
11.4 34.2 GO:0071149 TEAD-2-YAP complex(GO:0071149)
9.4 103.4 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
7.2 21.5 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
7.1 71.5 GO:0032009 early phagosome(GO:0032009)
7.0 21.0 GO:1990423 RZZ complex(GO:1990423)
6.5 77.6 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
5.7 28.7 GO:0072557 IPAF inflammasome complex(GO:0072557) NLRP1 inflammasome complex(GO:0072558) AIM2 inflammasome complex(GO:0097169)
5.3 32.0 GO:0071547 piP-body(GO:0071547)
5.3 26.6 GO:0034455 t-UTP complex(GO:0034455)
5.2 20.7 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
5.1 66.2 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
5.0 15.0 GO:0070821 tertiary granule membrane(GO:0070821)
4.7 14.0 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
4.6 18.5 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
4.5 27.1 GO:0034715 pICln-Sm protein complex(GO:0034715)
4.5 179.6 GO:0098636 protein complex involved in cell adhesion(GO:0098636)
4.4 17.6 GO:0031436 BRCA1-BARD1 complex(GO:0031436)
4.0 40.2 GO:0043020 NADPH oxidase complex(GO:0043020)
3.7 14.8 GO:0031092 platelet alpha granule membrane(GO:0031092)
3.5 10.5 GO:0055087 Ski complex(GO:0055087)
2.9 35.0 GO:0035631 CD40 receptor complex(GO:0035631)
2.7 13.5 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
2.6 10.5 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
2.6 20.9 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
2.5 7.5 GO:0032798 Swi5-Sfr1 complex(GO:0032798)
2.3 9.4 GO:0005588 collagen type V trimer(GO:0005588)
2.3 11.5 GO:0043625 delta DNA polymerase complex(GO:0043625)
2.2 6.6 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
2.2 39.9 GO:0030056 hemidesmosome(GO:0030056)
2.2 15.4 GO:0005828 kinetochore microtubule(GO:0005828)
2.0 6.0 GO:1990682 CSF1-CSF1R complex(GO:1990682)
2.0 11.8 GO:0070765 gamma-secretase complex(GO:0070765)
1.9 7.8 GO:1990584 cardiac Troponin complex(GO:1990584)
1.9 17.1 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
1.8 542.9 GO:0009897 external side of plasma membrane(GO:0009897)
1.7 5.0 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
1.7 13.3 GO:0000796 condensin complex(GO:0000796)
1.6 9.9 GO:0097209 epidermal lamellar body(GO:0097209)
1.6 46.6 GO:0042588 zymogen granule(GO:0042588)
1.6 338.1 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
1.5 23.0 GO:0072687 meiotic spindle(GO:0072687)
1.5 20.4 GO:0046658 anchored component of plasma membrane(GO:0046658)
1.3 5.4 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
1.3 9.0 GO:0016602 CCAAT-binding factor complex(GO:0016602)
1.2 25.7 GO:0001891 phagocytic cup(GO:0001891)
1.2 23.6 GO:0044217 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
1.2 10.6 GO:0031209 SCAR complex(GO:0031209)
1.2 4.7 GO:0000938 GARP complex(GO:0000938)
1.1 15.3 GO:0005766 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
1.1 6.3 GO:0033010 paranodal junction(GO:0033010)
1.1 13.7 GO:0042612 MHC class I protein complex(GO:0042612)
1.1 3.2 GO:0060187 cell pole(GO:0060187)
1.0 6.3 GO:1990111 spermatoproteasome complex(GO:1990111)
1.0 8.3 GO:0097208 alveolar lamellar body(GO:0097208)
1.0 22.0 GO:0001772 immunological synapse(GO:0001772)
1.0 5.9 GO:0035189 Rb-E2F complex(GO:0035189)
1.0 2.9 GO:0005745 m-AAA complex(GO:0005745)
1.0 6.7 GO:0042382 paraspeckles(GO:0042382)
1.0 4.8 GO:0031501 mannosyltransferase complex(GO:0031501)
0.9 24.9 GO:0000788 nuclear nucleosome(GO:0000788)
0.9 12.4 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.9 3.5 GO:0044326 dendritic spine neck(GO:0044326)
0.9 96.1 GO:0005884 actin filament(GO:0005884)
0.8 10.9 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.8 0.8 GO:0000814 ESCRT II complex(GO:0000814)
0.8 6.0 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.7 5.1 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.7 4.3 GO:0005726 perichromatin fibrils(GO:0005726)
0.7 10.0 GO:0016580 Sin3 complex(GO:0016580)
0.7 14.0 GO:0005614 interstitial matrix(GO:0005614)
0.7 5.4 GO:0031298 replication fork protection complex(GO:0031298)
0.7 11.5 GO:0001741 XY body(GO:0001741)
0.7 2.7 GO:0098553 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.7 7.3 GO:0097542 ciliary tip(GO:0097542)
0.7 12.5 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.6 9.0 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.6 10.8 GO:0032039 integrator complex(GO:0032039)
0.6 10.8 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.6 31.8 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.6 3.6 GO:0000243 commitment complex(GO:0000243)
0.6 4.7 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.6 10.9 GO:0042629 mast cell granule(GO:0042629)
0.5 8.2 GO:0030057 desmosome(GO:0030057)
0.5 2.1 GO:0031417 NatC complex(GO:0031417)
0.5 2.1 GO:0071797 LUBAC complex(GO:0071797)
0.5 2.6 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.5 3.1 GO:0097255 R2TP complex(GO:0097255)
0.5 3.5 GO:0097452 GAIT complex(GO:0097452)
0.5 25.5 GO:0030667 secretory granule membrane(GO:0030667)
0.5 33.6 GO:0031902 late endosome membrane(GO:0031902)
0.5 3.4 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.5 46.6 GO:0005604 basement membrane(GO:0005604)
0.4 9.9 GO:0001533 cornified envelope(GO:0001533)
0.4 37.5 GO:0072562 blood microparticle(GO:0072562)
0.4 1.3 GO:0070421 DNA ligase III-XRCC1 complex(GO:0070421)
0.4 1.3 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.4 9.4 GO:0002102 podosome(GO:0002102)
0.4 488.5 GO:0005615 extracellular space(GO:0005615)
0.4 38.4 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.4 80.1 GO:0016324 apical plasma membrane(GO:0016324)
0.4 12.4 GO:0035861 site of double-strand break(GO:0035861)
0.4 17.3 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.4 9.1 GO:0019897 extrinsic component of plasma membrane(GO:0019897)
0.4 4.8 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.4 46.9 GO:0030027 lamellipodium(GO:0030027)
0.4 2.2 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.4 10.6 GO:0005921 gap junction(GO:0005921)
0.4 16.3 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.4 7.5 GO:0001673 male germ cell nucleus(GO:0001673)
0.4 2.5 GO:0031415 NatA complex(GO:0031415)
0.3 46.3 GO:0005938 cell cortex(GO:0005938)
0.3 5.9 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.3 20.0 GO:0000786 nucleosome(GO:0000786) DNA packaging complex(GO:0044815)
0.3 5.2 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.3 3.2 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.3 22.2 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.3 15.7 GO:0032587 ruffle membrane(GO:0032587)
0.3 26.8 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.3 3.1 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.3 13.8 GO:0008023 transcription elongation factor complex(GO:0008023)
0.3 8.1 GO:0034451 centriolar satellite(GO:0034451)
0.3 6.3 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.3 91.1 GO:0009986 cell surface(GO:0009986)
0.3 63.8 GO:0005667 transcription factor complex(GO:0005667)
0.3 5.4 GO:0000421 autophagosome membrane(GO:0000421)
0.3 16.1 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.3 3.3 GO:0031932 TORC2 complex(GO:0031932)
0.2 1.2 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.2 0.7 GO:0044609 DBIRD complex(GO:0044609)
0.2 1.0 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.2 3.1 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.2 15.3 GO:0016363 nuclear matrix(GO:0016363)
0.2 49.9 GO:0000323 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.2 2.1 GO:0000242 pericentriolar material(GO:0000242)
0.2 3.0 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.2 3.3 GO:0060170 ciliary membrane(GO:0060170)
0.2 7.2 GO:0015030 Cajal body(GO:0015030)
0.2 5.2 GO:0005901 caveola(GO:0005901)
0.1 5.3 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 0.9 GO:0016591 DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
0.1 7.1 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 4.1 GO:0031519 PcG protein complex(GO:0031519)
0.1 2.6 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 0.5 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.1 3.2 GO:0031901 early endosome membrane(GO:0031901)
0.1 0.7 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1 0.9 GO:0017119 Golgi transport complex(GO:0017119)
0.1 9.5 GO:0031012 extracellular matrix(GO:0031012)
0.1 0.8 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.1 1.6 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.1 0.5 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 1.1 GO:0060077 inhibitory synapse(GO:0060077)
0.1 0.7 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.1 0.7 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 1.0 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 1.1 GO:0046930 pore complex(GO:0046930)
0.0 1.9 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.5 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 1.6 GO:0030139 endocytic vesicle(GO:0030139)
0.0 0.3 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.4 GO:0043596 nuclear replication fork(GO:0043596)
0.0 0.1 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 0.5 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
35.8 107.3 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
15.9 47.8 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
13.5 94.5 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
13.2 65.9 GO:0070891 lipoteichoic acid binding(GO:0070891)
10.9 32.8 GO:0002114 interleukin-33 receptor activity(GO:0002114)
10.7 85.8 GO:0019958 C-X-C chemokine binding(GO:0019958)
8.4 33.6 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
8.0 32.0 GO:0034584 piRNA binding(GO:0034584)
7.8 194.4 GO:0042288 MHC class I protein binding(GO:0042288)
7.4 37.2 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
6.8 20.4 GO:0071791 chemokine (C-C motif) ligand 5 binding(GO:0071791)
6.3 82.3 GO:0035325 Toll-like receptor binding(GO:0035325)
6.3 31.4 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
6.2 18.6 GO:0008384 NF-kappaB-inducing kinase activity(GO:0004704) IkappaB kinase activity(GO:0008384)
6.2 18.5 GO:0031721 haptoglobin binding(GO:0031720) hemoglobin alpha binding(GO:0031721)
6.1 36.8 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
5.8 215.4 GO:0008009 chemokine activity(GO:0008009)
5.7 51.3 GO:0042608 T cell receptor binding(GO:0042608)
5.3 26.6 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
5.2 15.6 GO:0044715 8-oxo-dGDP phosphatase activity(GO:0044715)
5.2 20.7 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
4.9 68.0 GO:0033691 sialic acid binding(GO:0033691)
4.9 14.6 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
4.7 18.9 GO:0055077 gap junction hemi-channel activity(GO:0055077)
4.6 36.6 GO:0032554 purine deoxyribonucleotide binding(GO:0032554)
4.3 47.8 GO:0008131 primary amine oxidase activity(GO:0008131)
4.3 30.1 GO:0031433 telethonin binding(GO:0031433)
4.2 37.9 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
4.0 11.9 GO:0008142 oxysterol binding(GO:0008142)
3.7 833.5 GO:0004252 serine-type endopeptidase activity(GO:0004252)
3.6 18.2 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
3.5 10.6 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
3.5 14.0 GO:0047276 N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
3.4 30.7 GO:1990446 U1 snRNP binding(GO:1990446)
3.4 23.6 GO:0001849 complement component C1q binding(GO:0001849)
3.4 10.1 GO:0008413 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
3.3 183.1 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
3.2 37.9 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
3.1 65.6 GO:0043274 phospholipase binding(GO:0043274)
3.1 9.2 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
3.0 39.1 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
3.0 6.0 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
3.0 20.9 GO:0003896 DNA primase activity(GO:0003896)
3.0 11.8 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
2.9 8.7 GO:0001847 opsonin receptor activity(GO:0001847)
2.8 14.0 GO:0052813 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
2.8 8.4 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
2.8 16.6 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
2.8 11.0 GO:0004185 serine-type carboxypeptidase activity(GO:0004185) serine-type exopeptidase activity(GO:0070008)
2.7 93.1 GO:1990841 promoter-specific chromatin binding(GO:1990841)
2.7 29.4 GO:0032036 myosin heavy chain binding(GO:0032036)
2.6 10.5 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
2.6 7.8 GO:0070976 TIR domain binding(GO:0070976)
2.4 56.0 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
2.4 11.9 GO:0019770 IgG receptor activity(GO:0019770)
2.4 59.2 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
2.4 9.4 GO:0000293 ferric-chelate reductase activity(GO:0000293)
2.3 23.4 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
2.3 7.0 GO:0030977 taurine binding(GO:0030977)
2.2 20.2 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
2.2 11.0 GO:0070052 collagen V binding(GO:0070052)
2.2 17.4 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
2.2 15.2 GO:0016803 ether hydrolase activity(GO:0016803)
2.1 21.5 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
2.1 8.4 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
2.1 6.3 GO:0004939 beta-adrenergic receptor activity(GO:0004939) bradykinin receptor binding(GO:0031711)
2.1 39.3 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
2.1 12.4 GO:0000150 recombinase activity(GO:0000150)
2.0 153.9 GO:1990782 protein tyrosine kinase binding(GO:1990782)
2.0 9.9 GO:0034186 apolipoprotein A-I binding(GO:0034186)
2.0 3.9 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
1.9 7.8 GO:0030172 troponin C binding(GO:0030172)
1.9 15.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
1.9 41.3 GO:0005212 structural constituent of eye lens(GO:0005212)
1.8 24.7 GO:0050431 transforming growth factor beta binding(GO:0050431)
1.8 22.9 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
1.8 5.3 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
1.7 7.0 GO:0034618 arginine binding(GO:0034618)
1.7 31.3 GO:0031996 thioesterase binding(GO:0031996)
1.7 5.2 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
1.7 11.9 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
1.7 5.0 GO:1990763 arrestin family protein binding(GO:1990763)
1.6 11.5 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
1.6 28.8 GO:0005522 profilin binding(GO:0005522)
1.6 12.6 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
1.6 31.4 GO:0019865 immunoglobulin binding(GO:0019865)
1.6 12.4 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
1.6 6.2 GO:0019784 NEDD8-specific protease activity(GO:0019784)
1.5 5.9 GO:0005534 galactose binding(GO:0005534)
1.4 10.1 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
1.3 18.3 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
1.3 1.3 GO:0070883 pre-miRNA binding(GO:0070883)
1.3 7.6 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
1.3 3.8 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
1.3 151.5 GO:0004519 endonuclease activity(GO:0004519)
1.2 7.5 GO:0046624 sphingolipid transporter activity(GO:0046624)
1.2 7.4 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
1.2 6.1 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
1.2 6.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
1.2 4.8 GO:0047619 acylcarnitine hydrolase activity(GO:0047619)
1.2 5.9 GO:0061676 importin-alpha family protein binding(GO:0061676)
1.1 25.0 GO:0017128 phospholipid scramblase activity(GO:0017128)
1.1 13.6 GO:0016493 C-C chemokine receptor activity(GO:0016493)
1.1 23.4 GO:0070006 metalloaminopeptidase activity(GO:0070006)
1.1 37.6 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
1.1 5.5 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
1.1 20.6 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
1.1 9.5 GO:0055104 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
1.1 24.3 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
1.0 3.0 GO:0030626 U12 snRNA binding(GO:0030626)
1.0 14.0 GO:0042043 neurexin family protein binding(GO:0042043)
1.0 21.9 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
1.0 9.9 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
1.0 8.9 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
1.0 6.8 GO:0035252 UDP-xylosyltransferase activity(GO:0035252)
1.0 5.8 GO:0035197 siRNA binding(GO:0035197)
1.0 4.8 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
1.0 10.5 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.9 256.2 GO:0030246 carbohydrate binding(GO:0030246)
0.9 4.7 GO:0004031 aldehyde oxidase activity(GO:0004031) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.9 5.3 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.9 2.6 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.9 9.5 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.8 5.0 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.8 4.2 GO:0048019 receptor antagonist activity(GO:0048019)
0.8 6.7 GO:0051525 NFAT protein binding(GO:0051525)
0.8 3.3 GO:0070568 guanylyltransferase activity(GO:0070568)
0.8 7.2 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.8 3.2 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.8 19.6 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.8 26.6 GO:0030515 snoRNA binding(GO:0030515)
0.8 3.8 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.8 6.0 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.7 4.5 GO:0004471 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.7 12.4 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.7 54.7 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.7 2.9 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.7 3.6 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.7 9.4 GO:0051400 BH domain binding(GO:0051400)
0.7 4.2 GO:0050786 N-formyl peptide receptor activity(GO:0004982) RAGE receptor binding(GO:0050786)
0.7 6.3 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.7 10.6 GO:0015643 toxic substance binding(GO:0015643)
0.7 45.8 GO:0004896 cytokine receptor activity(GO:0004896)
0.6 2.6 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.6 20.0 GO:0016860 intramolecular oxidoreductase activity(GO:0016860)
0.6 5.1 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.6 19.6 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.6 35.3 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.6 6.2 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.6 1.8 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.6 13.5 GO:0050699 WW domain binding(GO:0050699)
0.6 4.1 GO:0050700 CARD domain binding(GO:0050700)
0.6 4.1 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.5 14.2 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.5 4.7 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.5 9.3 GO:0031005 filamin binding(GO:0031005)
0.5 2.6 GO:0070411 I-SMAD binding(GO:0070411)
0.5 1.5 GO:0004046 aminoacylase activity(GO:0004046)
0.5 59.1 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.5 32.5 GO:0033613 activating transcription factor binding(GO:0033613)
0.5 4.3 GO:0034056 estrogen response element binding(GO:0034056)
0.5 17.1 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.5 4.7 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.5 3.3 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.5 2.8 GO:0005148 prolactin receptor binding(GO:0005148)
0.5 2.3 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105) type 2 fibroblast growth factor receptor binding(GO:0005111)
0.4 3.1 GO:0019104 DNA N-glycosylase activity(GO:0019104)
0.4 3.1 GO:0048185 activin binding(GO:0048185)
0.4 1.3 GO:0004956 prostaglandin D receptor activity(GO:0004956)
0.4 13.2 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.4 1.6 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.4 11.0 GO:0008237 metallopeptidase activity(GO:0008237)
0.4 13.4 GO:0022829 wide pore channel activity(GO:0022829)
0.4 13.7 GO:0042605 peptide antigen binding(GO:0042605)
0.4 13.6 GO:0030544 Hsp70 protein binding(GO:0030544)
0.4 3.4 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.4 5.5 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.4 1.5 GO:1990715 mRNA CDS binding(GO:1990715)
0.4 33.8 GO:0019887 protein kinase regulator activity(GO:0019887)
0.4 8.0 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.4 2.1 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.3 1.7 GO:0004586 ornithine decarboxylase activity(GO:0004586)
0.3 8.1 GO:0005044 scavenger receptor activity(GO:0005044)
0.3 4.6 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.3 1.0 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.3 1.9 GO:0001515 opioid peptide activity(GO:0001515)
0.3 1.2 GO:0004963 follicle-stimulating hormone receptor activity(GO:0004963)
0.3 7.9 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.3 6.0 GO:0001671 ATPase activator activity(GO:0001671)
0.3 2.7 GO:0008046 axon guidance receptor activity(GO:0008046)
0.3 10.6 GO:0061733 histone acetyltransferase activity(GO:0004402) peptide-lysine-N-acetyltransferase activity(GO:0061733)
0.3 1.2 GO:0045159 myosin II binding(GO:0045159)
0.3 26.8 GO:0035326 enhancer binding(GO:0035326)
0.3 58.4 GO:0004866 endopeptidase inhibitor activity(GO:0004866)
0.3 5.5 GO:0001968 fibronectin binding(GO:0001968)
0.3 0.9 GO:0030957 Tat protein binding(GO:0030957)
0.3 1.4 GO:0071253 connexin binding(GO:0071253)
0.3 8.8 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.3 2.5 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.3 2.2 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.3 67.2 GO:0003735 structural constituent of ribosome(GO:0003735)
0.3 6.8 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.2 1.5 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) chondroitin sulfotransferase activity(GO:0034481)
0.2 5.1 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.2 5.8 GO:0042923 neuropeptide binding(GO:0042923)
0.2 26.1 GO:0008201 heparin binding(GO:0008201)
0.2 3.5 GO:0008143 poly(A) binding(GO:0008143)
0.2 1.8 GO:0001848 complement binding(GO:0001848)
0.2 1.1 GO:0001032 RNA polymerase III type 3 promoter DNA binding(GO:0001032)
0.2 5.6 GO:0030332 cyclin binding(GO:0030332)
0.2 11.4 GO:0003725 double-stranded RNA binding(GO:0003725)
0.2 48.8 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.2 0.6 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.2 5.9 GO:0001786 phosphatidylserine binding(GO:0001786)
0.2 5.0 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.2 10.8 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.2 8.5 GO:0005518 collagen binding(GO:0005518)
0.2 6.7 GO:0005080 protein kinase C binding(GO:0005080)
0.2 3.0 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.2 1.5 GO:0015232 heme transporter activity(GO:0015232)
0.2 3.0 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.1 3.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 6.3 GO:0031490 chromatin DNA binding(GO:0031490)
0.1 0.6 GO:0035198 miRNA binding(GO:0035198)
0.1 11.5 GO:0001047 core promoter binding(GO:0001047)
0.1 3.1 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 3.7 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.1 5.8 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 2.5 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 2.5 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 0.7 GO:0008430 selenium binding(GO:0008430)
0.1 4.9 GO:0005507 copper ion binding(GO:0005507)
0.1 0.8 GO:0070182 DNA polymerase binding(GO:0070182)
0.1 3.1 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.1 1.7 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 9.3 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 2.5 GO:0030331 estrogen receptor binding(GO:0030331)
0.1 0.3 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.1 2.4 GO:0004707 MAP kinase activity(GO:0004707)
0.1 1.0 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 30.5 GO:0008047 enzyme activator activity(GO:0008047)
0.1 6.5 GO:0070851 growth factor receptor binding(GO:0070851)
0.1 2.7 GO:0005504 fatty acid binding(GO:0005504)
0.1 0.5 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 1.7 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 0.7 GO:0019841 retinol binding(GO:0019841)
0.1 1.5 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.1 2.4 GO:0016831 carboxy-lyase activity(GO:0016831)
0.1 4.3 GO:0003697 single-stranded DNA binding(GO:0003697)
0.1 1.8 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.1 0.7 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.1 1.0 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 3.5 GO:0043130 ubiquitin binding(GO:0043130)
0.0 1.0 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.1 GO:0052795 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.4 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 1.6 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.3 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.6 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
8.6 94.2 ST JAK STAT PATHWAY Jak-STAT Pathway
5.0 114.8 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
3.8 30.8 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
3.7 29.3 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
3.5 52.2 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
3.4 256.5 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
3.4 124.1 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
3.1 137.6 PID BCR 5PATHWAY BCR signaling pathway
3.0 87.7 PID CXCR3 PATHWAY CXCR3-mediated signaling events
2.8 123.0 PID IL12 2PATHWAY IL12-mediated signaling events
2.7 72.1 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
2.6 41.1 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
2.1 97.9 PID IL4 2PATHWAY IL4-mediated signaling events
1.9 90.6 NABA COLLAGENS Genes encoding collagen proteins
1.8 7.2 PID IL5 PATHWAY IL5-mediated signaling events
1.7 19.2 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
1.7 16.9 PID IL2 1PATHWAY IL2-mediated signaling events
1.6 26.2 ST G ALPHA S PATHWAY G alpha s Pathway
1.6 19.3 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
1.6 6.3 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
1.6 31.1 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
1.5 138.9 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
1.5 35.2 SIG CD40PATHWAYMAP Genes related to CD40 signaling
1.4 44.3 PID CDC42 REG PATHWAY Regulation of CDC42 activity
1.3 45.6 PID ARF6 PATHWAY Arf6 signaling events
1.3 23.8 PID CIRCADIAN PATHWAY Circadian rhythm pathway
1.2 49.8 PID AURORA B PATHWAY Aurora B signaling
1.2 42.6 PID BARD1 PATHWAY BARD1 signaling events
1.1 49.5 PID RAC1 PATHWAY RAC1 signaling pathway
1.0 12.5 PID IFNG PATHWAY IFN-gamma pathway
1.0 9.8 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.9 19.4 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.9 12.3 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.8 9.7 PID IL23 PATHWAY IL23-mediated signaling events
0.8 19.5 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.7 10.5 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.6 14.6 PID RAS PATHWAY Regulation of Ras family activation
0.6 181.3 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.6 28.2 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.6 6.1 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.6 10.0 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.6 11.0 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.5 11.1 PID ATF2 PATHWAY ATF-2 transcription factor network
0.5 20.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.5 5.3 PID GLYPICAN 1PATHWAY Glypican 1 network
0.5 7.2 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.5 5.1 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.5 5.5 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.4 4.8 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.4 8.7 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.4 4.1 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.4 4.1 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.4 12.2 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.4 1.4 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.3 2.4 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.3 14.0 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.3 2.4 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.3 5.1 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.3 8.2 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.3 6.4 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.3 12.8 PID E2F PATHWAY E2F transcription factor network
0.3 2.7 ST GA13 PATHWAY G alpha 13 Pathway
0.3 1.2 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.3 7.9 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.2 8.7 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.2 4.7 PID CONE PATHWAY Visual signal transduction: Cones
0.2 3.4 PID RHOA PATHWAY RhoA signaling pathway
0.2 2.8 PID ARF 3PATHWAY Arf1 pathway
0.1 1.8 PID MYC PATHWAY C-MYC pathway
0.1 4.0 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 6.1 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.1 5.4 PID AR PATHWAY Coregulation of Androgen receptor activity
0.1 4.4 PID CMYB PATHWAY C-MYB transcription factor network
0.1 3.6 PID P53 REGULATION PATHWAY p53 pathway
0.1 2.6 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 1.3 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.4 PID SHP2 PATHWAY SHP2 signaling
0.0 1.2 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.8 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.3 PID TGFBR PATHWAY TGF-beta receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
9.0 450.9 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
8.9 240.0 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
8.0 159.4 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
6.2 80.3 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
5.2 78.7 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
3.6 43.6 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
3.5 51.9 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
3.4 51.7 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
3.2 126.2 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
3.0 75.6 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
3.0 83.6 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
2.9 41.2 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
2.9 5.8 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
2.9 20.3 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
2.6 37.1 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
2.6 94.6 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
2.5 34.7 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
2.5 27.1 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
2.5 31.9 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
2.5 46.6 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
2.4 68.4 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
2.4 100.1 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
2.4 28.7 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
2.3 4.7 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
2.2 80.7 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
2.2 107.2 REACTOME LIPID DIGESTION MOBILIZATION AND TRANSPORT Genes involved in Lipid digestion, mobilization, and transport
2.1 22.8 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
1.8 106.7 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
1.3 43.0 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
1.3 5.3 REACTOME COMMON PATHWAY Genes involved in Common Pathway
1.3 16.5 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
1.3 13.8 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
1.2 39.4 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
1.2 22.5 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
1.1 19.3 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
1.1 16.5 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
1.1 18.3 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
1.0 11.5 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.9 20.5 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.9 8.7 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.9 11.2 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.8 30.7 REACTOME AMYLOIDS Genes involved in Amyloids
0.8 46.1 REACTOME EXTRACELLULAR MATRIX ORGANIZATION Genes involved in Extracellular matrix organization
0.8 2.4 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.8 15.6 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.7 12.2 REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION Genes involved in Nuclear Events (kinase and transcription factor activation)
0.7 65.9 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.6 14.6 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.6 5.5 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.6 16.3 REACTOME G1 PHASE Genes involved in G1 Phase
0.6 18.5 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.6 50.7 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.6 45.7 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.6 10.1 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.6 8.9 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.6 10.5 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.5 4.6 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.4 5.4 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.4 16.2 REACTOME RIG I MDA5 MEDIATED INDUCTION OF IFN ALPHA BETA PATHWAYS Genes involved in RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
0.4 18.1 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.4 7.3 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.4 6.9 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.4 7.2 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.4 16.5 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.4 5.7 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.4 7.7 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.4 7.7 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.3 5.0 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.3 42.3 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.3 3.1 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.3 10.9 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.3 5.2 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.3 4.4 REACTOME BASE EXCISION REPAIR Genes involved in Base Excision Repair
0.2 6.3 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.2 1.3 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.2 3.6 REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA Genes involved in Processing of Capped Intronless Pre-mRNA
0.2 44.5 REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)
0.2 2.3 REACTOME SIGNALING BY FGFR1 MUTANTS Genes involved in Signaling by FGFR1 mutants
0.2 17.9 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.2 0.9 REACTOME FORMATION OF THE HIV1 EARLY ELONGATION COMPLEX Genes involved in Formation of the HIV-1 Early Elongation Complex
0.2 13.9 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.2 2.5 REACTOME GPCR LIGAND BINDING Genes involved in GPCR ligand binding
0.1 27.2 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1 1.5 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.1 2.4 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1 7.9 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 3.8 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.1 1.5 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1 0.7 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 1.5 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.7 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.6 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.3 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 1.0 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0 1.0 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 1.3 REACTOME UNFOLDED PROTEIN RESPONSE Genes involved in Unfolded Protein Response
0.0 1.5 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.3 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.3 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.4 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.5 REACTOME SPHINGOLIPID METABOLISM Genes involved in Sphingolipid metabolism