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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Rarg

Z-value: 1.22

Motif logo

Transcription factors associated with Rarg

Gene Symbol Gene ID Gene Info
ENSRNOG00000012499 retinoic acid receptor, gamma

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Rargrn6_v1_chr7_-_143863186_143863186-0.071.8e-01Click!

Activity profile of Rarg motif

Sorted Z-values of Rarg motif

Promoter Log-likelihood Transcript Gene Gene Info
chr20_-_4489281 28.92 ENSRNOT00000031548
cytochrome P450, family 21, subfamily a, polypeptide 1
chr10_+_10774639 27.97 ENSRNOT00000061208
septin 12
chr1_-_88066101 26.48 ENSRNOT00000079473
ENSRNOT00000027893
ryanodine receptor 1
chr1_-_170431073 24.96 ENSRNOT00000024710
hemopexin
chr1_+_81763614 23.68 ENSRNOT00000027254
CD79a molecule
chr2_-_183031214 23.01 ENSRNOT00000013260
similar to RIKEN cDNA D930015E06
chr8_-_128711221 21.93 ENSRNOT00000055888
xin actin-binding repeat containing 1
chr3_-_80012750 21.91 ENSRNOT00000018154
nuclear receptor subfamily 1, group H, member 3
chr11_-_81639872 21.70 ENSRNOT00000047595
ENSRNOT00000090031
ENSRNOT00000081864
histidine-rich glycoprotein
chr1_+_165482155 21.14 ENSRNOT00000024005
uncoupling protein 3
chr3_+_171213936 20.59 ENSRNOT00000031586
phosphoenolpyruvate carboxykinase 1
chr1_-_197821936 20.55 ENSRNOT00000055027
CD19 molecule
chr9_-_16795887 19.99 ENSRNOT00000071609
Cd79a molecule-like
chr8_-_50539331 19.76 ENSRNOT00000088997

chr9_+_10956056 19.51 ENSRNOT00000073930
perilipin 5
chr12_+_16912249 18.68 ENSRNOT00000085936
transmembrane protein 184A
chr4_+_122244711 18.24 ENSRNOT00000038251
urocanate hydratase 1
chr20_-_4316715 17.88 ENSRNOT00000031704
complement C4B (Chido blood group)
chr7_-_29152442 17.81 ENSRNOT00000079774
myosin binding protein C, slow type
chr13_+_78805347 17.69 ENSRNOT00000003748
serpin family C member 1
chrX_+_15273933 17.63 ENSRNOT00000075082
erythroid transcription factor
chr6_-_127816055 17.59 ENSRNOT00000013175
serine (or cysteine) proteinase inhibitor, clade A, member 3M
chr4_-_165629996 16.71 ENSRNOT00000068185
ENSRNOT00000007427
Y box binding protein 3
chr3_-_80543031 16.69 ENSRNOT00000022233
coagulation factor II
chr4_-_181348799 16.59 ENSRNOT00000033743
hypothetical protein LOC690783
chr1_+_248723397 16.25 ENSRNOT00000072188
mannose-binding protein C-like
chr3_-_62524996 16.16 ENSRNOT00000002114
nuclear factor, erythroid 2-like 2
chr1_-_80599572 15.47 ENSRNOT00000024832
apolipoprotein C4
chr5_-_19368431 15.31 ENSRNOT00000012819
cytochrome P450, family 7, subfamily a, polypeptide 1
chr20_-_2678141 15.28 ENSRNOT00000072377
ENSRNOT00000083833
complement component 4A (Rodgers blood group)
chr8_-_56393233 15.25 ENSRNOT00000016263
ferredoxin 1
chr1_+_65576535 15.24 ENSRNOT00000026575
solute carrier family 27 member 5
chr1_-_98490315 15.08 ENSRNOT00000056490
claudin domain containing 2
chr12_+_22153983 14.92 ENSRNOT00000080775
ENSRNOT00000001894
procollagen C-endopeptidase enhancer
chr13_-_47397890 14.69 ENSRNOT00000005505
complement component 4 binding protein, beta
chrX_+_54734385 14.57 ENSRNOT00000005023
nuclear receptor subfamily 0, group B, member 1
chr1_+_219329574 14.48 ENSRNOT00000071109
calcium binding protein 2
chr9_+_17734345 14.42 ENSRNOT00000067104
calpain 11
chr10_-_109729019 14.39 ENSRNOT00000054959
protein phosphatase 1, regulatory subunit 27
chr5_-_59165160 14.34 ENSRNOT00000029035
family with sequence similarity 221, member B
chr4_+_61850348 14.31 ENSRNOT00000013423
aldo-keto reductase family 1, member B7
chr5_+_90338795 14.14 ENSRNOT00000077864
ENSRNOT00000058882
similar to RIKEN cDNA 2310003M01
chr7_-_14435967 14.14 ENSRNOT00000074801
peptidoglycan recognition protein 2
chr14_-_86164341 13.98 ENSRNOT00000086343
ENSRNOT00000080147
glucokinase
chr8_-_111761871 13.95 ENSRNOT00000056483
similar to RIKEN cDNA 1300017J02
chr18_+_56071478 13.83 ENSRNOT00000025344
ENSRNOT00000025354
CD74 molecule
chr4_-_30338679 13.74 ENSRNOT00000012050
paraoxonase 3
chr6_+_128046780 13.38 ENSRNOT00000078064
Ab1-233
chr8_+_106317124 13.25 ENSRNOT00000018411
nicotinamide nucleotide adenylyltransferase 3
chr8_+_110982777 13.17 ENSRNOT00000010992
kyphoscoliosis peptidase
chr2_+_198655437 13.07 ENSRNOT00000028781
hemochromatosis type 2 (juvenile)
chr6_-_135089409 12.93 ENSRNOT00000089238
hypothetical LOC299330
chr3_-_2727616 12.92 ENSRNOT00000061904
complement C8 gamma chain
chr15_-_57651041 12.80 ENSRNOT00000072138
spermatid associated
chr16_-_49003246 12.75 ENSRNOT00000089501
acyl-CoA synthetase long-chain family member 1
chr3_-_156905892 12.69 ENSRNOT00000022424
elastin microfibril interfacer 3
chr2_+_114423533 12.65 ENSRNOT00000091221
solute carrier family 2 member 2
chr1_+_257076221 12.52 ENSRNOT00000044895
solute carrier family 35, member G1
chr4_-_30556814 12.51 ENSRNOT00000012760
pyruvate dehydrogenase kinase 4
chr13_+_52625441 12.47 ENSRNOT00000012095
troponin I1, slow skeletal type
chr1_-_89539210 12.42 ENSRNOT00000077462
ENSRNOT00000028644
hepsin
chr1_+_80777014 12.41 ENSRNOT00000079758
predicted gene, 19345
chr2_-_23289266 12.36 ENSRNOT00000061708
betaine-homocysteine S-methyltransferase 2
chr10_+_4950484 12.22 ENSRNOT00000003450
protamine 2
chr1_+_193424812 12.20 ENSRNOT00000019939
aquaporin 8
chr20_-_45259928 12.12 ENSRNOT00000087226
solute carrier family 16 member 10
chr11_+_30904733 12.10 ENSRNOT00000036027
melanocortin 2 receptor accessory protein
chr8_+_116857684 12.10 ENSRNOT00000026711
macrophage stimulating 1
chr5_+_160306727 12.03 ENSRNOT00000016648
agmatinase
chr3_-_153952108 12.03 ENSRNOT00000050465
adipogenin
chr5_-_29601748 11.95 ENSRNOT00000011330
2,4-dienoyl-CoA reductase 1
chrX_-_15693473 11.80 ENSRNOT00000013758
prickle planar cell polarity protein 3
chr19_-_55284663 11.63 ENSRNOT00000018387
snail family transcriptional repressor 3
chr20_-_6195463 11.48 ENSRNOT00000092474
peroxisomal, testis specific 1
chrX_-_71169865 11.45 ENSRNOT00000050415
interleukin 2 receptor subunit gamma
chr1_+_215610368 11.19 ENSRNOT00000078903
ENSRNOT00000087781
troponin I2, fast skeletal type
chr13_+_75105615 11.15 ENSRNOT00000076653
tumor protein p53 inducible protein 3
chr8_-_114449956 11.13 ENSRNOT00000056414
collagen type VI alpha 6 chain
chr14_-_86796378 11.12 ENSRNOT00000092021
myosin IG
chr16_+_18736154 11.02 ENSRNOT00000015723
mannose-binding lectin (protein A) 1
chr5_-_166282831 10.92 ENSRNOT00000021348
retinol binding protein 7
chr8_+_96564877 10.82 ENSRNOT00000017879
5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
chr5_-_147784311 10.81 ENSRNOT00000074172
family with sequence similarity 167, member B
chr1_+_261281543 10.78 ENSRNOT00000018890
ankyrin repeat domain 2
chr11_+_74057361 10.78 ENSRNOT00000048746
carboxypeptidase N subunit 2
chr2_-_197860699 10.67 ENSRNOT00000028740
extracellular matrix protein 1
chr6_-_142903440 10.59 ENSRNOT00000075707

chr3_-_8981362 10.52 ENSRNOT00000086717
carnitine O-acetyltransferase
chr20_-_4698718 10.51 ENSRNOT00000047527
RT1 class I, locus CE7
chr13_-_68360664 10.50 ENSRNOT00000030971
hemicentin 1
chr5_+_152290084 10.45 ENSRNOT00000089849
absent in melanoma 1-like
chr19_+_15094309 10.44 ENSRNOT00000083500
carboxylesterase 1F
chr16_+_50179458 10.29 ENSRNOT00000041946
coagulation factor XI
chr16_-_60427474 10.28 ENSRNOT00000051720
protein phosphatase 1, regulatory subunit 3B
chr14_-_80973456 10.25 ENSRNOT00000013257
HGF activator
chr3_-_127500709 10.19 ENSRNOT00000006330
hydroxyacid oxidase 1
chr9_-_61975640 10.16 ENSRNOT00000085744
boule homolog, RNA binding protein
chr10_-_105412627 10.15 ENSRNOT00000034817
glutamine rich 2
chr6_+_128973956 10.12 ENSRNOT00000075399
family with sequence similarity 181, member A
chr1_+_167197549 10.11 ENSRNOT00000027427
ADP-ribosyltransferase 1
chr5_+_79179417 10.08 ENSRNOT00000010454
orosomucoid 1
chr10_-_58973020 10.03 ENSRNOT00000020379
smoothelin-like 2
chr8_-_63155825 9.95 ENSRNOT00000011820
TBC1 domain family, member 21
chr12_+_19196611 9.95 ENSRNOT00000001801
alpha-2-glycoprotein 1, zinc-binding
chr1_-_102255459 9.95 ENSRNOT00000067392
USH1 protein network component harmonin
chr1_-_219312240 9.78 ENSRNOT00000066691
similar to hypothetical protein MGC37914
chrX_-_64726210 9.68 ENSRNOT00000076012
ENSRNOT00000086265
ankyrin repeat and SOCS box-containing 12
chr1_-_80744831 9.59 ENSRNOT00000025913
B-cell CLL/lymphoma 3
chr9_-_54457753 9.59 ENSRNOT00000020032
signal transducer and activator of transcription 1
chr1_-_221321459 9.58 ENSRNOT00000028406
ENSRNOT00000084800
DNA polymerase alpha 2, accessory subunit
chr6_-_143195445 9.55 ENSRNOT00000078672

chr1_-_189359730 9.55 ENSRNOT00000066597
RGD1559600
chr16_-_71040847 9.53 ENSRNOT00000020606
steroidogenic acute regulatory protein
chr4_-_114768029 9.51 ENSRNOT00000083404
T-cell leukemia homeobox 2
chr15_+_24159647 9.47 ENSRNOT00000082675
galectin 3
chr9_-_119332967 9.46 ENSRNOT00000021048
myosin light chain 12A
chr14_+_38030189 9.38 ENSRNOT00000035623
TXK tyrosine kinase
chr14_+_13192347 9.32 ENSRNOT00000000092
anthrax toxin receptor 2
chr8_+_117486083 9.31 ENSRNOT00000027552
ENSRNOT00000088705
protein kinase cAMP-dependent type 2 regulatory subunit alpha
chr2_+_252018597 9.28 ENSRNOT00000020452
mucolipin 2
chr4_+_56591715 9.28 ENSRNOT00000041207
family with sequence similarity 71, member F1
chr7_+_117351648 9.24 ENSRNOT00000056421
sphingomyelin phosphodiesterase 5
chr16_-_7250924 9.20 ENSRNOT00000025394
stabilin 1
chr20_-_9876008 9.17 ENSRNOT00000001537
trefoil factor 2
chr1_+_64506735 9.14 ENSRNOT00000086331
NLR family, pyrin domain containing 12
chr15_+_33606124 9.10 ENSRNOT00000065210

chr6_-_143195143 9.09 ENSRNOT00000081337

chr16_+_21288876 9.08 ENSRNOT00000027990
cartilage intermediate layer protein 2
chr8_-_63150753 9.06 ENSRNOT00000078666
TBC1 domain family, member 21
chr10_+_104377748 9.01 ENSRNOT00000080714
LLGL2, scribble cell polarity complex component
chrX_+_158569056 9.00 ENSRNOT00000074170
placenta-specific protein 1-like
chr4_-_144318580 9.00 ENSRNOT00000007591
ssu-2 homolog
chr1_+_102924059 8.96 ENSRNOT00000078137

chr1_+_41325462 8.95 ENSRNOT00000081017
ENSRNOT00000078494
ENSRNOT00000088168
estrogen receptor 1
chr6_-_25211494 8.95 ENSRNOT00000009634
xanthine dehydrogenase
chr6_+_104718512 8.91 ENSRNOT00000007947
SPARC related modular calcium binding 1
chr17_+_4212890 8.81 ENSRNOT00000024467
testin gene
chr4_-_129619142 8.75 ENSRNOT00000047453
leiomodin 3
chr16_-_54513349 8.71 ENSRNOT00000014809
ENSRNOT00000015127
solute carrier family 7 member 2
chr12_+_30603242 8.66 ENSRNOT00000068460
septin 14
chr9_-_9985630 8.66 ENSRNOT00000071780
crumbs 3, cell polarity complex component
chr4_+_169161585 8.63 ENSRNOT00000079785
epithelial membrane protein 1
chr19_+_55094585 8.58 ENSRNOT00000068452
zinc finger protein, multitype 1
chr19_-_10976396 8.58 ENSRNOT00000073239
NLR family, CARD domain containing 5
chr1_-_198486157 8.57 ENSRNOT00000022758
zymogen granule protein 16
chr11_-_71419223 8.54 ENSRNOT00000002407
transferrin receptor
chr10_-_67479077 8.50 ENSRNOT00000090278
transcription elongation factor, mitochondrial
chr8_+_50310405 8.44 ENSRNOT00000073507
SIK family kinase 3
chr17_+_22619891 8.38 ENSRNOT00000060403
androgen-dependent TFPI-regulating protein
chr8_-_23146689 8.36 ENSRNOT00000092200
acid phosphatase 5, tartrate resistant
chr13_+_44424689 8.35 ENSRNOT00000005206
aminocarboxymuconate semialdehyde decarboxylase
chr10_-_5533695 8.29 ENSRNOT00000051564
ribosomal protein L39-like
chr5_-_110706656 8.29 ENSRNOT00000033781
IZUMO family member 3
chr5_+_154260062 8.27 ENSRNOT00000074998
cannabinoid receptor 2
chr10_+_3655038 8.25 ENSRNOT00000045047
calcineurin-like phosphoesterase domain containing 1
chr1_+_229066045 8.22 ENSRNOT00000016454
glycine-N-acyltransferase
chr10_-_56426012 8.16 ENSRNOT00000092506
ENSRNOT00000084068
similar to RIKEN cDNA 4933402P03
chr10_-_5260608 8.15 ENSRNOT00000003572
class II, major histocompatibility complex, transactivator
chr10_-_29196563 8.14 ENSRNOT00000005205
fatty acid binding protein 6
chr6_-_142534112 8.08 ENSRNOT00000073598
immunoglobulin heavy variable 1-49
chr2_-_60657712 8.04 ENSRNOT00000040348
retinoic acid induced 14
chr14_-_17171580 8.03 ENSRNOT00000085525
ADP-ribosyltransferase 3
chr8_-_60086403 8.00 ENSRNOT00000020544
electron transfer flavoprotein alpha subunit
chr4_-_113902399 7.98 ENSRNOT00000087788
T-cell leukemia homeobox 2
chr16_+_1979191 7.91 ENSRNOT00000014382
peptidylprolyl isomerase F
chr9_-_71900044 7.86 ENSRNOT00000020322
isocitrate dehydrogenase (NADP(+)) 1, cytosolic
chr8_+_115193146 7.85 ENSRNOT00000056391
IQ motif containing F1
chr3_+_143119687 7.84 ENSRNOT00000006608
cystatin 12
chr1_+_100199057 7.82 ENSRNOT00000025831
kallikrein 1
chr4_-_98995590 7.80 ENSRNOT00000008698
threonine synthase-like 2
chr10_+_103543895 7.79 ENSRNOT00000077882
Cd300 molecule-like family member D
chr4_-_98735346 7.73 ENSRNOT00000008473
testis expressed 37
chr10_+_106785077 7.73 ENSRNOT00000075047
transmembrane channel-like 8
chr20_-_13657943 7.69 ENSRNOT00000032290
pre-B lymphocyte 3
chr7_-_145048283 7.66 ENSRNOT00000055275
gametocyte specific factor 1
chr4_-_60358562 7.63 ENSRNOT00000018001
coiled-coil-helix-coiled-coil-helix domain containing 3
chr5_-_136053210 7.61 ENSRNOT00000025903
kinesin family member 2C
chr9_-_44617210 7.57 ENSRNOT00000074343
lysozyme G1
chr6_-_47848026 7.55 ENSRNOT00000011048
ENSRNOT00000090017
allantoicase
chr20_-_7307280 7.52 ENSRNOT00000000583
ENSRNOT00000079933
SAM pointed domain containing ets transcription factor
chrX_-_157095274 7.51 ENSRNOT00000084088
ATP binding cassette subfamily D member 1
chr7_+_11769400 7.48 ENSRNOT00000044417
junctional sarcoplasmic reticulum protein 1
chr4_-_169093135 7.47 ENSRNOT00000011461
phosphatidylethanolamine binding protein 2
chr5_+_124442293 7.42 ENSRNOT00000041922
similar to novel protein
chr2_+_189423559 7.40 ENSRNOT00000029076
tropomyosin 3
chr4_+_148782479 7.35 ENSRNOT00000018133
similar to hypothetical protein MGC6835
chr3_-_72447801 7.32 ENSRNOT00000088815
purinergic receptor P2X 3
chr6_-_135026449 7.30 ENSRNOT00000009444
hypothetical LOC299330
chr15_-_34392066 7.26 ENSRNOT00000027315
transglutaminase 1
chr4_-_6449949 7.25 ENSRNOT00000062026
polypeptide N-acetylgalactosaminyltransferase-like 5
chr12_-_2007516 7.23 ENSRNOT00000037564
peroxisomal biogenesis factor 11 gamma
chr10_-_67478848 7.23 ENSRNOT00000005325
transcription elongation factor, mitochondrial
chr15_+_61069581 7.21 ENSRNOT00000084333
von Willebrand factor A domain containing 8
chr1_+_100708693 7.18 ENSRNOT00000071054
ENSRNOT00000071503
izumo sperm-egg fusion protein 2-like
chr4_-_155051429 7.16 ENSRNOT00000020094
killer cell lectin like receptor G1
chr20_+_4959294 7.13 ENSRNOT00000074223
heat shock protein family A (Hsp70) member 1 like
chr1_+_100830064 7.06 ENSRNOT00000027320
interleukin 4 induced 1
chr10_+_94471476 7.02 ENSRNOT00000088697
testicular cell adhesion molecule 1
chr8_-_111850075 7.01 ENSRNOT00000082097
CDV3 homolog
chr1_-_107385257 7.00 ENSRNOT00000074296
coiled-coil domain containing 179

Network of associatons between targets according to the STRING database.

First level regulatory network of Rarg

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
10.7 42.9 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
7.2 21.7 GO:0097037 heme export(GO:0097037)
6.5 19.5 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
5.6 16.7 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738) response to thyrotropin-releasing hormone(GO:1905225)
5.4 16.2 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
4.9 24.6 GO:0048550 negative regulation of pinocytosis(GO:0048550)
4.9 14.7 GO:0045959 negative regulation of complement activation, classical pathway(GO:0045959)
4.8 19.4 GO:0002325 natural killer cell differentiation involved in immune response(GO:0002325) negative regulation of natural killer cell differentiation(GO:0032824) regulation of natural killer cell differentiation involved in immune response(GO:0032826) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827)
4.7 18.7 GO:0018992 germ-line sex determination(GO:0018992)
4.4 17.7 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
4.4 13.2 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
4.4 17.6 GO:0030221 basophil differentiation(GO:0030221)
4.4 17.5 GO:0006114 glycerol biosynthetic process(GO:0006114)
4.3 8.6 GO:0060375 regulation of mast cell differentiation(GO:0060375) transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
4.2 16.7 GO:1902219 negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
4.1 12.4 GO:0034769 basement membrane disassembly(GO:0034769)
3.8 15.2 GO:0046951 ketone body biosynthetic process(GO:0046951)
3.8 18.9 GO:0009732 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
3.7 22.1 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
3.6 18.2 GO:0006548 histidine catabolic process(GO:0006548)
3.6 10.8 GO:0042560 folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
3.5 21.0 GO:0045343 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343) positive regulation of MHC class I biosynthetic process(GO:0045345)
3.5 10.5 GO:0003162 atrioventricular node development(GO:0003162)
3.3 23.0 GO:0033088 negative regulation of immature T cell proliferation in thymus(GO:0033088)
3.2 15.9 GO:0015755 fructose transport(GO:0015755)
3.2 9.5 GO:0017143 insecticide metabolic process(GO:0017143)
3.2 9.5 GO:1903769 negative regulation of cell proliferation in bone marrow(GO:1903769)
3.1 12.5 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
2.9 8.7 GO:0089718 amino acid import across plasma membrane(GO:0089718)
2.8 2.8 GO:0006579 amino-acid betaine catabolic process(GO:0006579)
2.8 13.8 GO:0002905 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
2.8 22.0 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
2.7 8.2 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
2.6 7.9 GO:1902445 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
2.6 10.5 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
2.6 15.5 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
2.5 10.2 GO:0009441 glycolate metabolic process(GO:0009441)
2.5 7.5 GO:0043605 cellular amide catabolic process(GO:0043605)
2.4 12.1 GO:0015801 aromatic amino acid transport(GO:0015801)
2.4 7.2 GO:0044375 regulation of peroxisome size(GO:0044375)
2.4 12.0 GO:0008295 spermidine biosynthetic process(GO:0008295)
2.4 9.6 GO:0034240 negative regulation of macrophage fusion(GO:0034240)
2.3 4.6 GO:2000259 positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
2.3 9.0 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
2.2 9.0 GO:1990375 baculum development(GO:1990375)
2.1 4.2 GO:0071298 cellular response to L-ascorbic acid(GO:0071298)
2.1 6.3 GO:0002554 serotonin secretion by platelet(GO:0002554)
2.1 2.1 GO:0003130 BMP signaling pathway involved in heart induction(GO:0003130) endodermal-mesodermal cell signaling(GO:0003133) endodermal-mesodermal cell signaling involved in heart induction(GO:0003134)
2.1 28.9 GO:0006705 mineralocorticoid biosynthetic process(GO:0006705)
2.0 6.1 GO:0070904 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
2.0 6.0 GO:0002462 tolerance induction to nonself antigen(GO:0002462)
2.0 9.9 GO:1904970 brush border assembly(GO:1904970)
2.0 7.8 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
1.9 27.3 GO:0001867 complement activation, lectin pathway(GO:0001867)
1.9 5.8 GO:1900739 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740) protein localization to vacuolar membrane(GO:1903778)
1.9 9.5 GO:0002225 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antibacterial peptide production(GO:0002803)
1.9 7.6 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
1.9 5.6 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
1.9 5.6 GO:1904139 regulation of macrophage colony-stimulating factor signaling pathway(GO:1902226) regulation of response to macrophage colony-stimulating factor(GO:1903969) regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903972) microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
1.9 11.1 GO:0038096 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096)
1.8 10.9 GO:0006102 isocitrate metabolic process(GO:0006102)
1.8 5.4 GO:0010037 response to carbon dioxide(GO:0010037)
1.8 9.0 GO:0046110 xanthine catabolic process(GO:0009115) xanthine metabolic process(GO:0046110)
1.8 5.3 GO:0042197 chlorinated hydrocarbon metabolic process(GO:0042196) halogenated hydrocarbon metabolic process(GO:0042197)
1.7 12.2 GO:0015722 canalicular bile acid transport(GO:0015722)
1.7 17.3 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
1.6 12.9 GO:0071267 amino acid salvage(GO:0043102) L-methionine salvage(GO:0071267)
1.6 4.8 GO:0030091 protein repair(GO:0030091)
1.6 4.8 GO:0042509 regulation of tyrosine phosphorylation of STAT protein(GO:0042509) positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
1.6 20.5 GO:0006968 cellular defense response(GO:0006968)
1.6 3.2 GO:0033087 negative regulation of immature T cell proliferation(GO:0033087)
1.6 12.5 GO:1990034 calcium ion export from cell(GO:1990034)
1.6 7.8 GO:0051790 threonine metabolic process(GO:0006566) short-chain fatty acid biosynthetic process(GO:0051790)
1.6 9.3 GO:0097338 response to clozapine(GO:0097338)
1.5 7.6 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
1.5 15.2 GO:0070995 NADPH oxidation(GO:0070995)
1.5 4.6 GO:0006742 NADP catabolic process(GO:0006742)
1.5 4.5 GO:1901873 regulation of post-translational protein modification(GO:1901873)
1.5 4.5 GO:1903923 protein processing in phagocytic vesicle(GO:1900756) regulation of protein processing in phagocytic vesicle(GO:1903921) positive regulation of protein processing in phagocytic vesicle(GO:1903923)
1.5 12.1 GO:0045721 negative regulation of gluconeogenesis(GO:0045721) mammary duct terminal end bud growth(GO:0060763)
1.5 7.5 GO:0042758 long-chain fatty acid catabolic process(GO:0042758)
1.5 10.3 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
1.4 9.9 GO:0071763 nuclear membrane organization(GO:0071763)
1.4 26.5 GO:0043931 ossification involved in bone maturation(GO:0043931)
1.4 8.3 GO:0046874 quinolinate metabolic process(GO:0046874)
1.4 4.1 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
1.4 6.8 GO:0050917 sensory perception of umami taste(GO:0050917)
1.3 17.2 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
1.3 13.0 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
1.3 15.3 GO:0070857 regulation of bile acid biosynthetic process(GO:0070857)
1.3 7.6 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
1.3 5.0 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
1.2 8.7 GO:0051694 pointed-end actin filament capping(GO:0051694)
1.2 5.0 GO:0050689 negative regulation of defense response to virus by host(GO:0050689)
1.2 3.7 GO:0061206 mesonephros morphogenesis(GO:0061206) mesonephric nephron development(GO:0061215) mesonephric nephron morphogenesis(GO:0061228) mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis(GO:0061235) regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061295) negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061296) mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:1901146)
1.2 4.9 GO:0060155 apolipoprotein A-I-mediated signaling pathway(GO:0038027) platelet dense granule organization(GO:0060155)
1.2 4.7 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
1.2 4.7 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
1.2 3.5 GO:1990790 response to glial cell derived neurotrophic factor(GO:1990790) cellular response to glial cell derived neurotrophic factor(GO:1990792)
1.2 6.9 GO:0035701 hematopoietic stem cell migration(GO:0035701)
1.1 9.2 GO:0043031 negative regulation of macrophage activation(GO:0043031)
1.1 11.4 GO:0032831 regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829) positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032831)
1.1 4.5 GO:0038158 granulocyte colony-stimulating factor signaling pathway(GO:0038158)
1.1 14.6 GO:0016540 protein autoprocessing(GO:0016540)
1.1 21.1 GO:1990845 adaptive thermogenesis(GO:1990845)
1.1 3.3 GO:0045065 cytotoxic T cell differentiation(GO:0045065)
1.1 3.3 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158) positive regulation of ER to Golgi vesicle-mediated transport(GO:1902953)
1.1 8.7 GO:0001920 negative regulation of receptor recycling(GO:0001920)
1.1 8.6 GO:0002439 chronic inflammatory response to antigenic stimulus(GO:0002439)
1.1 7.5 GO:0060480 lung goblet cell differentiation(GO:0060480)
1.0 3.1 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
1.0 7.3 GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
1.0 14.6 GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
1.0 12.5 GO:0014883 transition between fast and slow fiber(GO:0014883)
1.0 17.5 GO:0048484 enteric nervous system development(GO:0048484)
1.0 2.0 GO:2000669 negative regulation of dendritic cell apoptotic process(GO:2000669)
1.0 7.1 GO:0007060 male meiosis chromosome segregation(GO:0007060)
1.0 4.0 GO:0030449 regulation of complement activation(GO:0030449)
1.0 4.0 GO:0021730 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740)
1.0 3.0 GO:0070268 cuticle development(GO:0042335) cornification(GO:0070268)
1.0 3.9 GO:1990164 histone H2A phosphorylation(GO:1990164)
1.0 5.8 GO:1990928 response to amino acid starvation(GO:1990928)
1.0 4.8 GO:0072344 rescue of stalled ribosome(GO:0072344)
1.0 18.1 GO:0006958 complement activation, classical pathway(GO:0006958)
1.0 1.9 GO:0090081 regulation of heart induction by regulation of canonical Wnt signaling pathway(GO:0090081)
0.9 8.5 GO:0033572 transferrin transport(GO:0033572)
0.9 3.8 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.9 8.3 GO:0038171 cannabinoid signaling pathway(GO:0038171)
0.9 3.7 GO:0036118 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.9 4.6 GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.9 1.8 GO:0002434 immune complex clearance(GO:0002434)
0.9 8.0 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.9 6.2 GO:1901299 negative regulation of hydrogen peroxide-mediated programmed cell death(GO:1901299)
0.9 10.3 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.8 18.1 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.8 12.3 GO:0042407 cristae formation(GO:0042407)
0.8 9.8 GO:0030238 male sex determination(GO:0030238)
0.8 4.8 GO:0060721 regulation of spongiotrophoblast cell proliferation(GO:0060721) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.8 2.3 GO:1904100 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.8 2.3 GO:0002277 myeloid dendritic cell activation involved in immune response(GO:0002277)
0.7 2.2 GO:0001698 gastrin-induced gastric acid secretion(GO:0001698)
0.7 2.2 GO:0010265 SCF complex assembly(GO:0010265)
0.7 2.2 GO:0042732 D-xylose metabolic process(GO:0042732)
0.7 4.3 GO:0046490 isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate metabolic process(GO:0046490)
0.7 4.3 GO:0006868 glutamine transport(GO:0006868)
0.7 5.0 GO:0060631 meiotic DNA double-strand break formation(GO:0042138) regulation of meiosis I(GO:0060631)
0.7 6.8 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086)
0.7 6.1 GO:0046085 adenosine metabolic process(GO:0046085)
0.7 2.7 GO:0002084 protein depalmitoylation(GO:0002084)
0.7 2.0 GO:0006288 base-excision repair, DNA ligation(GO:0006288)
0.6 3.2 GO:0036233 glycine import(GO:0036233)
0.6 5.8 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.6 5.7 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.6 6.3 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.6 1.9 GO:1990743 protein sialylation(GO:1990743)
0.6 6.8 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.6 1.9 GO:1990108 protein linear deubiquitination(GO:1990108)
0.6 3.1 GO:0038094 Fc-gamma receptor signaling pathway(GO:0038094)
0.6 1.8 GO:0097052 L-kynurenine metabolic process(GO:0097052)
0.6 1.8 GO:1902568 regulation of eosinophil degranulation(GO:0043309) positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.6 3.6 GO:1901843 membrane depolarization during bundle of His cell action potential(GO:0086048) positive regulation of high voltage-gated calcium channel activity(GO:1901843)
0.6 8.9 GO:0032060 bleb assembly(GO:0032060)
0.6 3.5 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.6 13.4 GO:0008206 bile acid metabolic process(GO:0008206)
0.6 7.6 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.6 2.9 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.6 2.3 GO:0060178 regulation of exocyst localization(GO:0060178)
0.6 4.5 GO:0035646 endosome to melanosome transport(GO:0035646) pigment accumulation(GO:0043476) cellular pigment accumulation(GO:0043482) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757) regulation of rubidium ion transport(GO:2000680)
0.6 1.7 GO:1903847 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.6 2.2 GO:0002540 leukotriene production involved in inflammatory response(GO:0002540)
0.6 3.4 GO:0070836 caveola assembly(GO:0070836)
0.5 1.6 GO:1901227 negative regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901227)
0.5 7.5 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.5 7.4 GO:0090266 regulation of spindle checkpoint(GO:0090231) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.5 5.8 GO:0006777 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.5 3.1 GO:0010528 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529) DNA hypermethylation(GO:0044026) negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.5 14.0 GO:0019835 cytolysis(GO:0019835)
0.5 8.2 GO:0006544 glycine metabolic process(GO:0006544)
0.5 2.0 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.5 6.0 GO:0046485 ether lipid metabolic process(GO:0046485)
0.5 1.0 GO:2000041 regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.5 15.6 GO:0030261 chromosome condensation(GO:0030261)
0.5 7.3 GO:0010838 positive regulation of keratinocyte proliferation(GO:0010838)
0.5 10.2 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.5 1.9 GO:0010832 negative regulation of myotube differentiation(GO:0010832)
0.5 13.4 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.5 1.4 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
0.5 3.3 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.5 2.4 GO:0071955 recycling endosome to Golgi transport(GO:0071955)
0.5 2.8 GO:0015705 iodide transport(GO:0015705)
0.5 3.2 GO:0006621 protein retention in ER lumen(GO:0006621)
0.5 3.2 GO:0030321 transepithelial chloride transport(GO:0030321)
0.5 5.0 GO:0030259 lipid glycosylation(GO:0030259)
0.5 3.6 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.5 1.4 GO:0030222 eosinophil differentiation(GO:0030222)
0.4 17.5 GO:0045214 sarcomere organization(GO:0045214)
0.4 5.3 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.4 17.8 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.4 4.7 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.4 2.1 GO:0051454 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.4 2.1 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.4 3.4 GO:0006751 glutathione catabolic process(GO:0006751)
0.4 10.7 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.4 20.6 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.4 5.3 GO:0050961 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.4 2.4 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.4 3.2 GO:0060346 bone trabecula formation(GO:0060346)
0.4 8.3 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.4 2.0 GO:0060620 regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.4 2.3 GO:0033629 negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.4 1.2 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.4 3.1 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.4 2.7 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.4 4.5 GO:0035881 amacrine cell differentiation(GO:0035881)
0.4 4.5 GO:0035745 CD4-positive, alpha-beta T cell cytokine production(GO:0035743) T-helper 2 cell cytokine production(GO:0035745)
0.4 3.7 GO:0035900 response to isolation stress(GO:0035900)
0.4 2.6 GO:0010041 response to iron(III) ion(GO:0010041)
0.4 4.0 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.4 6.9 GO:0031581 hemidesmosome assembly(GO:0031581)
0.4 1.1 GO:0015680 intracellular copper ion transport(GO:0015680)
0.4 7.5 GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.3 7.7 GO:0002675 positive regulation of acute inflammatory response(GO:0002675)
0.3 4.5 GO:0051013 microtubule severing(GO:0051013)
0.3 7.1 GO:0042026 protein refolding(GO:0042026)
0.3 11.2 GO:0006739 NADP metabolic process(GO:0006739)
0.3 10.4 GO:0006270 DNA replication initiation(GO:0006270)
0.3 13.1 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.3 2.0 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.3 9.2 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.3 6.2 GO:0097435 fibril organization(GO:0097435)
0.3 1.0 GO:2001268 negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
0.3 4.2 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.3 3.8 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.3 6.3 GO:0046337 phosphatidylethanolamine metabolic process(GO:0046337)
0.3 0.9 GO:0072076 nephrogenic mesenchyme development(GO:0072076)
0.3 1.2 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.3 2.5 GO:0019388 galactose catabolic process(GO:0019388)
0.3 1.2 GO:0071492 cellular response to UV-A(GO:0071492)
0.3 1.8 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.3 1.8 GO:0090367 negative regulation of mRNA modification(GO:0090367)
0.3 2.1 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.3 8.4 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.3 2.4 GO:0044598 polyketide metabolic process(GO:0030638) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
0.3 6.3 GO:0045116 protein neddylation(GO:0045116)
0.3 4.5 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.3 6.4 GO:1903846 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.3 1.1 GO:0071718 sodium-independent icosanoid transport(GO:0071718)
0.3 0.9 GO:0097503 sialylation(GO:0097503)
0.3 0.8 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.3 6.7 GO:0034508 centromere complex assembly(GO:0034508)
0.3 2.1 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.3 13.2 GO:0007528 neuromuscular junction development(GO:0007528)
0.3 4.4 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.3 4.2 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.3 4.7 GO:0036158 outer dynein arm assembly(GO:0036158)
0.3 3.1 GO:0007028 cytoplasm organization(GO:0007028)
0.3 3.8 GO:0072673 lamellipodium morphogenesis(GO:0072673)
0.3 1.5 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.3 3.8 GO:0010269 response to selenium ion(GO:0010269)
0.3 1.0 GO:0015811 L-cystine transport(GO:0015811)
0.2 6.6 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.2 3.6 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.2 2.8 GO:0032836 glomerular basement membrane development(GO:0032836)
0.2 0.7 GO:0032789 saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
0.2 1.4 GO:2000823 regulation of androgen receptor activity(GO:2000823)
0.2 4.1 GO:0048240 sperm capacitation(GO:0048240)
0.2 3.8 GO:0010447 response to acidic pH(GO:0010447)
0.2 3.5 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.2 2.1 GO:0014807 regulation of somitogenesis(GO:0014807)
0.2 7.4 GO:0050873 brown fat cell differentiation(GO:0050873)
0.2 1.0 GO:0022615 protein to membrane docking(GO:0022615)
0.2 1.8 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.2 5.8 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.2 7.4 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.2 0.8 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.2 4.6 GO:0060046 regulation of acrosome reaction(GO:0060046)
0.2 1.9 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.2 0.7 GO:0061370 testosterone biosynthetic process(GO:0061370)
0.2 8.3 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.2 5.9 GO:0050892 intestinal absorption(GO:0050892)
0.2 1.3 GO:0042492 gamma-delta T cell differentiation(GO:0042492)
0.2 2.2 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.2 7.4 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.2 1.4 GO:0000042 protein targeting to Golgi(GO:0000042)
0.2 1.4 GO:0032025 response to cobalt ion(GO:0032025)
0.2 2.4 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.2 5.1 GO:0006749 glutathione metabolic process(GO:0006749)
0.2 3.1 GO:0030225 macrophage differentiation(GO:0030225)
0.2 2.9 GO:0009414 response to water deprivation(GO:0009414)
0.2 0.7 GO:1900118 negative regulation of execution phase of apoptosis(GO:1900118)
0.2 0.5 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.2 2.3 GO:0071173 mitotic spindle assembly checkpoint(GO:0007094) spindle checkpoint(GO:0031577) spindle assembly checkpoint(GO:0071173) mitotic spindle checkpoint(GO:0071174)
0.2 7.3 GO:1902041 regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902041)
0.2 3.2 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.2 1.7 GO:1904707 positive regulation of vascular smooth muscle cell proliferation(GO:1904707)
0.2 6.4 GO:0007140 male meiosis(GO:0007140)
0.2 3.7 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.2 2.5 GO:0042832 defense response to protozoan(GO:0042832)
0.2 1.8 GO:0051281 positive regulation of release of sequestered calcium ion into cytosol(GO:0051281)
0.2 1.2 GO:0000012 single strand break repair(GO:0000012)
0.2 8.3 GO:1902017 regulation of cilium assembly(GO:1902017)
0.2 2.9 GO:0006458 'de novo' protein folding(GO:0006458)
0.1 3.3 GO:0030500 regulation of bone mineralization(GO:0030500)
0.1 3.8 GO:0042775 mitochondrial ATP synthesis coupled electron transport(GO:0042775)
0.1 0.7 GO:1903909 regulation of receptor clustering(GO:1903909) regulation of AMPA glutamate receptor clustering(GO:1904717)
0.1 0.9 GO:0010587 miRNA catabolic process(GO:0010587)
0.1 1.0 GO:0006685 sphingomyelin catabolic process(GO:0006685) glycerophospholipid catabolic process(GO:0046475)
0.1 2.0 GO:0015693 magnesium ion transport(GO:0015693)
0.1 2.9 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.1 59.1 GO:0007283 spermatogenesis(GO:0007283)
0.1 0.7 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.1 0.5 GO:1903350 response to dopamine(GO:1903350) cellular response to dopamine(GO:1903351)
0.1 4.0 GO:0051341 regulation of oxidoreductase activity(GO:0051341)
0.1 1.1 GO:0072189 ureter development(GO:0072189)
0.1 7.7 GO:0002377 immunoglobulin production(GO:0002377)
0.1 2.8 GO:0050891 multicellular organismal water homeostasis(GO:0050891)
0.1 2.0 GO:0008053 mitochondrial fusion(GO:0008053)
0.1 1.0 GO:0000338 protein deneddylation(GO:0000338)
0.1 0.7 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.1 1.6 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 1.0 GO:0000733 DNA strand renaturation(GO:0000733)
0.1 2.7 GO:0043403 skeletal muscle tissue regeneration(GO:0043403)
0.1 7.3 GO:0045667 regulation of osteoblast differentiation(GO:0045667)
0.1 0.9 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1 1.3 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.1 0.4 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1 0.3 GO:0036451 cap mRNA methylation(GO:0036451)
0.1 0.9 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.1 2.0 GO:0000266 mitochondrial fission(GO:0000266)
0.1 3.3 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.1 1.7 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.1 0.7 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.1 1.6 GO:0032438 melanosome organization(GO:0032438) pigment granule organization(GO:0048753)
0.1 3.3 GO:0035904 aorta development(GO:0035904)
0.1 6.5 GO:0010952 positive regulation of peptidase activity(GO:0010952)
0.1 2.9 GO:0034113 heterotypic cell-cell adhesion(GO:0034113)
0.1 0.7 GO:0071498 cellular response to fluid shear stress(GO:0071498)
0.1 2.4 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.1 3.8 GO:0007338 single fertilization(GO:0007338)
0.1 4.2 GO:0009311 oligosaccharide metabolic process(GO:0009311)
0.1 3.2 GO:0032680 regulation of tumor necrosis factor production(GO:0032680) regulation of tumor necrosis factor superfamily cytokine production(GO:1903555)
0.1 1.4 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.1 2.1 GO:1901998 toxin transport(GO:1901998)
0.1 7.5 GO:0042742 defense response to bacterium(GO:0042742)
0.1 0.1 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.1 1.8 GO:0097421 liver regeneration(GO:0097421)
0.1 10.1 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.1 2.3 GO:0006672 ceramide metabolic process(GO:0006672)
0.0 0.9 GO:0006379 mRNA cleavage(GO:0006379)
0.0 1.4 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.0 1.7 GO:0043507 positive regulation of JUN kinase activity(GO:0043507)
0.0 1.8 GO:0050715 positive regulation of cytokine secretion(GO:0050715)
0.0 0.3 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 1.2 GO:0006809 nitric oxide biosynthetic process(GO:0006809)
0.0 0.3 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.0 1.9 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.3 GO:2000059 negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000059)
0.0 1.9 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.0 1.0 GO:0002011 morphogenesis of an epithelial sheet(GO:0002011)
0.0 0.5 GO:0097320 membrane tubulation(GO:0097320)
0.0 0.1 GO:0008594 photoreceptor cell morphogenesis(GO:0008594)
0.0 2.3 GO:0006334 nucleosome assembly(GO:0006334)
0.0 2.4 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0 0.1 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 2.6 GO:0001890 placenta development(GO:0001890)
0.0 0.5 GO:0030728 ovulation(GO:0030728)
0.0 1.2 GO:0014065 phosphatidylinositol 3-kinase signaling(GO:0014065)
0.0 0.7 GO:0034605 cellular response to heat(GO:0034605)
0.0 14.5 GO:0055114 oxidation-reduction process(GO:0055114)
0.0 0.2 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.0 0.6 GO:0006446 regulation of translational initiation(GO:0006446)
0.0 0.6 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.2 GO:1904948 midbrain dopaminergic neuron differentiation(GO:1904948)
0.0 20.3 GO:0007608 sensory perception of smell(GO:0007608)
0.0 0.1 GO:0035196 dsRNA fragmentation(GO:0031050) production of miRNAs involved in gene silencing by miRNA(GO:0035196) production of small RNA involved in gene silencing by RNA(GO:0070918)
0.0 0.3 GO:0042130 negative regulation of T cell proliferation(GO:0042130)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
5.9 23.7 GO:0019815 B cell receptor complex(GO:0019815)
5.4 21.7 GO:0061474 phagolysosome membrane(GO:0061474)
4.6 13.8 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
4.1 12.2 GO:0046691 intracellular canaliculus(GO:0046691)
3.6 21.6 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
2.9 26.5 GO:0030314 junctional membrane complex(GO:0030314)
2.3 28.1 GO:0005861 troponin complex(GO:0005861)
2.1 21.1 GO:0031105 septin complex(GO:0031105)
2.0 44.1 GO:0044217 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
1.7 29.4 GO:0030061 mitochondrial crista(GO:0030061)
1.7 5.0 GO:0005745 m-AAA complex(GO:0005745)
1.5 20.6 GO:0042612 MHC class I protein complex(GO:0042612)
1.5 14.6 GO:0042788 polysomal ribosome(GO:0042788)
1.3 15.5 GO:0034385 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
1.2 8.6 GO:0060205 cytoplasmic membrane-bounded vesicle lumen(GO:0060205)
1.2 3.7 GO:0036117 hyaluranon cable(GO:0036117)
1.2 9.6 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
1.1 4.5 GO:0005956 protein kinase CK2 complex(GO:0005956)
1.1 4.5 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
1.1 139.9 GO:0072562 blood microparticle(GO:0072562)
1.1 7.6 GO:0061617 MICOS complex(GO:0061617)
1.1 13.0 GO:0005859 muscle myosin complex(GO:0005859)
1.1 9.6 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
1.1 7.4 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
1.1 6.3 GO:0030313 cell outer membrane(GO:0009279) cell envelope(GO:0030313) external encapsulating structure part(GO:0044462)
1.0 9.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
1.0 10.3 GO:0042587 glycogen granule(GO:0042587)
1.0 8.6 GO:0005641 nuclear envelope lumen(GO:0005641)
0.9 14.9 GO:0045180 basal cortex(GO:0045180)
0.9 5.4 GO:0097209 epidermal lamellar body(GO:0097209)
0.9 9.0 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.9 3.6 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.9 2.6 GO:0005962 mitochondrial isocitrate dehydrogenase complex (NAD+)(GO:0005962) isocitrate dehydrogenase complex (NAD+)(GO:0045242)
0.9 16.2 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.8 4.2 GO:0071953 elastic fiber(GO:0071953)
0.8 7.6 GO:0032437 cuticular plate(GO:0032437)
0.8 4.1 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.8 3.2 GO:1990005 granular vesicle(GO:1990005)
0.8 6.8 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.8 3.8 GO:0044194 cytolytic granule(GO:0044194)
0.7 2.0 GO:0070421 DNA ligase III-XRCC1 complex(GO:0070421)
0.6 6.8 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.6 2.4 GO:0035363 histone locus body(GO:0035363)
0.6 5.9 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.6 4.6 GO:0031931 TORC1 complex(GO:0031931)
0.6 8.0 GO:0005916 fascia adherens(GO:0005916)
0.6 7.3 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.5 16.7 GO:0005921 gap junction(GO:0005921)
0.5 3.6 GO:0097524 sperm plasma membrane(GO:0097524)
0.5 2.0 GO:0002947 tumor necrosis factor receptor superfamily complex(GO:0002947)
0.5 4.5 GO:0005826 actomyosin contractile ring(GO:0005826)
0.5 26.3 GO:0009925 basal plasma membrane(GO:0009925)
0.5 8.2 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.5 64.7 GO:0001669 acrosomal vesicle(GO:0001669)
0.5 1.8 GO:0036128 CatSper complex(GO:0036128)
0.5 1.4 GO:1990590 ATF1-ATF4 transcription factor complex(GO:1990590)
0.5 3.6 GO:0000796 condensin complex(GO:0000796)
0.5 13.2 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.5 3.2 GO:0016942 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.5 2.7 GO:0016012 sarcoglycan complex(GO:0016012)
0.4 7.0 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.4 3.8 GO:0002177 manchette(GO:0002177)
0.4 3.8 GO:0031209 SCAR complex(GO:0031209)
0.4 4.9 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.4 3.3 GO:0000243 commitment complex(GO:0000243)
0.4 11.1 GO:0001891 phagocytic cup(GO:0001891)
0.4 4.0 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.4 1.2 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.4 3.8 GO:0070531 BRCA1-A complex(GO:0070531)
0.4 7.1 GO:0031527 filopodium membrane(GO:0031527)
0.4 1.9 GO:0071797 LUBAC complex(GO:0071797)
0.4 4.4 GO:0008385 IkappaB kinase complex(GO:0008385)
0.4 26.5 GO:0005581 collagen trimer(GO:0005581)
0.3 6.3 GO:0001520 outer dense fiber(GO:0001520)
0.3 12.5 GO:0005637 nuclear inner membrane(GO:0005637)
0.3 1.7 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.3 24.8 GO:0005811 lipid particle(GO:0005811)
0.3 1.0 GO:0070820 tertiary granule(GO:0070820)
0.3 1.7 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.3 48.1 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.3 6.8 GO:0008305 integrin complex(GO:0008305)
0.3 3.9 GO:0000801 central element(GO:0000801)
0.3 3.6 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.3 1.8 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.3 4.7 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.3 2.0 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.3 7.6 GO:0035371 microtubule plus-end(GO:0035371)
0.3 2.0 GO:0071986 Ragulator complex(GO:0071986)
0.3 25.8 GO:0005604 basement membrane(GO:0005604)
0.3 1.8 GO:0097452 GAIT complex(GO:0097452)
0.3 1.8 GO:0000322 storage vacuole(GO:0000322)
0.3 0.8 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.3 32.2 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.2 11.9 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.2 6.7 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.2 5.8 GO:0000421 autophagosome membrane(GO:0000421)
0.2 1.4 GO:0001651 dense fibrillar component(GO:0001651)
0.2 2.9 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.2 8.5 GO:0001772 immunological synapse(GO:0001772)
0.2 4.2 GO:0097225 sperm midpiece(GO:0097225)
0.2 12.1 GO:0030667 secretory granule membrane(GO:0030667)
0.2 5.6 GO:0031306 intrinsic component of mitochondrial outer membrane(GO:0031306)
0.2 7.8 GO:0016235 aggresome(GO:0016235)
0.2 1.1 GO:0070449 elongin complex(GO:0070449)
0.2 1.9 GO:0000138 Golgi trans cisterna(GO:0000138)
0.2 3.5 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.2 16.7 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.2 5.0 GO:0000795 synaptonemal complex(GO:0000795)
0.2 16.6 GO:0016605 PML body(GO:0016605)
0.2 2.6 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.2 39.6 GO:0005759 mitochondrial matrix(GO:0005759)
0.2 10.4 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.2 2.0 GO:0030057 desmosome(GO:0030057)
0.2 8.2 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.2 38.0 GO:0005667 transcription factor complex(GO:0005667)
0.1 8.2 GO:0034707 chloride channel complex(GO:0034707)
0.1 3.4 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.1 1.3 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 21.7 GO:0032993 protein-DNA complex(GO:0032993)
0.1 5.4 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 6.9 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.1 4.9 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 2.8 GO:0034706 sodium channel complex(GO:0034706)
0.1 0.5 GO:0044316 cone cell pedicle(GO:0044316)
0.1 7.2 GO:0031526 brush border membrane(GO:0031526)
0.1 1.4 GO:0031083 BLOC-1 complex(GO:0031083)
0.1 6.6 GO:0032587 ruffle membrane(GO:0032587)
0.1 3.3 GO:0031201 SNARE complex(GO:0031201)
0.1 3.8 GO:0015030 Cajal body(GO:0015030)
0.1 0.8 GO:0042555 MCM complex(GO:0042555)
0.1 3.8 GO:0030141 secretory granule(GO:0030141)
0.1 3.6 GO:0000776 kinetochore(GO:0000776)
0.1 13.6 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 82.2 GO:0005615 extracellular space(GO:0005615)
0.1 13.6 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.1 5.2 GO:0005923 bicellular tight junction(GO:0005923)
0.1 0.3 GO:0098576 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553) lumenal side of membrane(GO:0098576)
0.1 7.0 GO:0001650 fibrillar center(GO:0001650)
0.1 3.5 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 3.3 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 1.8 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 15.1 GO:0045177 apical part of cell(GO:0045177)
0.0 2.8 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 4.7 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 2.5 GO:0005776 autophagosome(GO:0005776)
0.0 0.4 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.2 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.0 36.6 GO:0005739 mitochondrion(GO:0005739)
0.0 0.6 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 1.0 GO:0005840 ribosome(GO:0005840)
0.0 0.9 GO:0045095 keratin filament(GO:0045095)
0.0 0.3 GO:0001533 cornified envelope(GO:0001533)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
7.3 21.9 GO:0032810 sterol response element binding(GO:0032810)
5.3 21.1 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
5.2 15.7 GO:0030337 DNA polymerase processivity factor activity(GO:0030337)
4.8 19.4 GO:0016019 peptidoglycan receptor activity(GO:0016019)
4.6 13.7 GO:0046573 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
4.4 13.2 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
4.1 12.2 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
4.0 12.1 GO:0031783 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
3.6 14.6 GO:0050682 AF-2 domain binding(GO:0050682)
3.6 10.8 GO:0016882 cyclo-ligase activity(GO:0016882)
3.4 20.2 GO:0008865 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
3.3 19.5 GO:0035473 lipase binding(GO:0035473)
3.2 12.8 GO:0003987 acetate-CoA ligase activity(GO:0003987)
3.1 12.5 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
3.0 12.0 GO:0008670 2,4-dienoyl-CoA reductase (NADPH) activity(GO:0008670)
3.0 26.9 GO:0015232 heme transporter activity(GO:0015232)
2.8 17.0 GO:0042289 MHC class II protein binding(GO:0042289)
2.7 10.8 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
2.6 7.9 GO:0051990 (R)-2-hydroxyglutarate dehydrogenase activity(GO:0051990)
2.6 7.8 GO:0070905 serine binding(GO:0070905)
2.6 17.9 GO:0001849 complement component C1q binding(GO:0001849)
2.5 10.2 GO:0003973 (S)-2-hydroxy-acid oxidase activity(GO:0003973)
2.3 18.1 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
2.2 15.6 GO:0031014 troponin T binding(GO:0031014)
2.2 13.1 GO:0098821 BMP receptor activity(GO:0098821)
2.1 10.7 GO:0005134 interleukin-2 receptor binding(GO:0005134)
2.1 59.5 GO:0008395 steroid hydroxylase activity(GO:0008395)
2.1 16.7 GO:0070053 thrombospondin receptor activity(GO:0070053)
2.1 8.3 GO:0004949 cannabinoid receptor activity(GO:0004949)
2.1 6.2 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
2.0 6.1 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
1.9 11.4 GO:0019976 interleukin-2 binding(GO:0019976)
1.9 9.5 GO:0050785 advanced glycation end-product receptor activity(GO:0050785)
1.9 22.7 GO:0070008 serine-type exopeptidase activity(GO:0070008)
1.9 5.6 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
1.9 11.2 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
1.8 9.0 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798)
1.8 9.0 GO:0016726 xanthine dehydrogenase activity(GO:0004854) oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor(GO:0016726)
1.8 15.9 GO:0008494 translation activator activity(GO:0008494)
1.7 8.7 GO:0001155 TFIIIA-class transcription factor binding(GO:0001155)
1.7 6.9 GO:0004452 isopentenyl-diphosphate delta-isomerase activity(GO:0004452)
1.6 13.0 GO:0008172 S-methyltransferase activity(GO:0008172)
1.6 14.3 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
1.6 12.6 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
1.6 4.7 GO:0004517 nitric-oxide synthase activity(GO:0004517)
1.5 13.9 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
1.5 4.6 GO:0031871 proteinase activated receptor binding(GO:0031871)
1.5 15.2 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
1.5 12.1 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
1.5 4.5 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797)
1.5 4.5 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
1.5 19.6 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
1.5 4.5 GO:0031762 follicle-stimulating hormone receptor binding(GO:0031762)
1.5 8.7 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
1.4 5.8 GO:0008265 Mo-molybdopterin cofactor sulfurase activity(GO:0008265)
1.4 4.2 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
1.4 4.1 GO:0031714 C5a anaphylatoxin chemotactic receptor binding(GO:0031714)
1.4 4.1 GO:0016748 succinyltransferase activity(GO:0016748)
1.4 8.2 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
1.3 6.7 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
1.3 9.3 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
1.3 9.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
1.3 10.5 GO:0016413 O-acetyltransferase activity(GO:0016413)
1.3 5.2 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
1.3 9.1 GO:0030881 beta-2-microglobulin binding(GO:0030881)
1.3 13.0 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
1.3 3.8 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
1.3 5.1 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
1.3 7.5 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
1.2 12.2 GO:0046870 cadmium ion binding(GO:0046870)
1.2 4.8 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
1.2 14.4 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
1.2 12.0 GO:0032036 myosin heavy chain binding(GO:0032036)
1.2 3.6 GO:0086057 voltage-gated calcium channel activity involved in bundle of His cell action potential(GO:0086057)
1.2 12.9 GO:0001848 complement binding(GO:0001848)
1.2 8.1 GO:0032052 bile acid binding(GO:0032052)
1.2 9.2 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
1.1 20.6 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
1.1 7.9 GO:0016018 cyclosporin A binding(GO:0016018)
1.1 6.7 GO:0048039 ubiquinone binding(GO:0048039)
1.1 8.8 GO:0004035 alkaline phosphatase activity(GO:0004035)
1.1 6.4 GO:0019788 NEDD8 transferase activity(GO:0019788)
1.1 8.5 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
1.0 4.1 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
1.0 22.5 GO:0019865 immunoglobulin binding(GO:0019865)
1.0 4.9 GO:0034186 apolipoprotein A-I binding(GO:0034186)
1.0 5.8 GO:0032027 myosin light chain binding(GO:0032027)
0.9 3.7 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.9 11.7 GO:0003796 lysozyme activity(GO:0003796)
0.9 12.2 GO:0015250 water channel activity(GO:0015250)
0.9 17.0 GO:0005537 mannose binding(GO:0005537)
0.8 6.5 GO:0003996 acyl-CoA ligase activity(GO:0003996) fatty-acyl-CoA synthase activity(GO:0004321)
0.8 14.4 GO:0001618 virus receptor activity(GO:0001618)
0.8 2.4 GO:0047025 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
0.8 3.2 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.8 4.6 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.8 3.8 GO:0030348 syntaxin-3 binding(GO:0030348)
0.7 2.2 GO:0004051 arachidonate 5-lipoxygenase activity(GO:0004051)
0.7 11.1 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.7 7.3 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.7 2.2 GO:0031720 haptoglobin binding(GO:0031720)
0.7 2.1 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.7 2.1 GO:0038100 nodal binding(GO:0038100)
0.7 4.9 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.7 2.7 GO:0034603 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.7 3.3 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.7 2.0 GO:0008481 sphinganine kinase activity(GO:0008481)
0.7 9.2 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.7 2.6 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.6 3.2 GO:0046923 ER retention sequence binding(GO:0046923)
0.6 3.8 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.6 6.3 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.6 1.8 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
0.6 1.8 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.6 14.4 GO:0001671 ATPase activator activity(GO:0001671)
0.6 14.8 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.6 2.3 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.6 20.4 GO:0042605 peptide antigen binding(GO:0042605)
0.6 3.4 GO:0036374 gamma-glutamyltransferase activity(GO:0003840) glutathione hydrolase activity(GO:0036374)
0.6 3.3 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.5 8.7 GO:0005523 tropomyosin binding(GO:0005523)
0.5 2.7 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.5 3.7 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.5 3.6 GO:0050700 CARD domain binding(GO:0050700)
0.5 2.1 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.5 21.1 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.5 5.0 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.5 7.0 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.5 4.0 GO:0008430 selenium binding(GO:0008430)
0.5 3.9 GO:0035184 histone threonine kinase activity(GO:0035184)
0.5 14.9 GO:0016504 peptidase activator activity(GO:0016504)
0.5 1.9 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.5 24.0 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.5 1.4 GO:0035939 microsatellite binding(GO:0035939)
0.4 6.2 GO:0017154 semaphorin receptor activity(GO:0017154)
0.4 9.1 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.4 9.0 GO:0015106 bicarbonate transmembrane transporter activity(GO:0015106)
0.4 11.2 GO:0008198 ferrous iron binding(GO:0008198)
0.4 5.8 GO:0042171 lysophosphatidic acid acyltransferase activity(GO:0042171)
0.4 9.8 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.4 3.3 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.4 13.4 GO:0008307 structural constituent of muscle(GO:0008307)
0.4 3.2 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.4 5.1 GO:0016805 dipeptidase activity(GO:0016805)
0.4 8.5 GO:0051010 microtubule plus-end binding(GO:0051010)
0.4 6.1 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.4 0.7 GO:0070401 NADP+ binding(GO:0070401)
0.4 2.6 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.4 3.3 GO:1990446 U1 snRNA binding(GO:0030619) U1 snRNP binding(GO:1990446)
0.4 18.4 GO:0016836 hydro-lyase activity(GO:0016836)
0.4 4.3 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.4 2.8 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.3 10.0 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.3 2.0 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.3 1.0 GO:0031766 galanin receptor binding(GO:0031763) type 2 galanin receptor binding(GO:0031765) type 3 galanin receptor binding(GO:0031766)
0.3 2.8 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.3 6.3 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.3 1.2 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.3 60.5 GO:0004866 endopeptidase inhibitor activity(GO:0004866) endopeptidase regulator activity(GO:0061135)
0.3 3.2 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.3 2.3 GO:0042608 T cell receptor binding(GO:0042608)
0.3 0.9 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.3 4.4 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.3 1.7 GO:0000150 recombinase activity(GO:0000150)
0.3 3.8 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.3 19.7 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.3 4.2 GO:0015926 glucosidase activity(GO:0015926)
0.3 2.1 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.3 0.8 GO:0000171 ribonuclease MRP activity(GO:0000171)
0.3 3.6 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.3 5.3 GO:0019825 oxygen binding(GO:0019825)
0.3 52.6 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.2 11.2 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.2 4.6 GO:0017127 cholesterol transporter activity(GO:0017127)
0.2 28.4 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.2 4.7 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.2 2.4 GO:0070402 NADPH binding(GO:0070402)
0.2 6.3 GO:0005501 retinoid binding(GO:0005501)
0.2 4.6 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.2 6.2 GO:0008527 taste receptor activity(GO:0008527)
0.2 17.2 GO:0051082 unfolded protein binding(GO:0051082)
0.2 1.1 GO:0032767 copper-dependent protein binding(GO:0032767)
0.2 15.0 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.2 9.4 GO:0003823 antigen binding(GO:0003823)
0.2 2.5 GO:0070182 DNA polymerase binding(GO:0070182)
0.2 1.4 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.2 10.4 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.2 3.4 GO:0070300 phosphatidic acid binding(GO:0070300)
0.2 4.0 GO:0070840 dynein complex binding(GO:0070840)
0.2 1.2 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014) 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.2 1.9 GO:0050750 co-receptor binding(GO:0039706) low-density lipoprotein particle receptor binding(GO:0050750)
0.2 1.9 GO:0019808 polyamine binding(GO:0019808)
0.2 2.6 GO:0004579 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.2 0.9 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.2 6.2 GO:0004364 glutathione transferase activity(GO:0004364)
0.2 2.4 GO:0017166 vinculin binding(GO:0017166)
0.2 15.5 GO:0031490 chromatin DNA binding(GO:0031490)
0.2 9.4 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.2 0.7 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.2 3.1 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.2 5.7 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors(GO:0016667)
0.2 1.7 GO:0008097 5S rRNA binding(GO:0008097)
0.2 4.0 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 10.8 GO:0050660 flavin adenine dinucleotide binding(GO:0050660)
0.1 1.0 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.1 1.8 GO:0019104 DNA N-glycosylase activity(GO:0019104)
0.1 2.2 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.1 0.7 GO:0050692 DBD domain binding(GO:0050692)
0.1 0.8 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 15.2 GO:0008201 heparin binding(GO:0008201)
0.1 9.8 GO:0002020 protease binding(GO:0002020)
0.1 6.1 GO:0033613 activating transcription factor binding(GO:0033613)
0.1 3.0 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 3.2 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.1 1.1 GO:0051400 BH domain binding(GO:0051400)
0.1 3.5 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor(GO:0016655)
0.1 2.8 GO:0017025 TBP-class protein binding(GO:0017025)
0.1 2.8 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 8.2 GO:0005254 chloride channel activity(GO:0005254)
0.1 15.4 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 1.1 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.1 0.7 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.1 0.3 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.1 3.3 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 10.8 GO:0030165 PDZ domain binding(GO:0030165)
0.1 3.3 GO:0016831 carboxy-lyase activity(GO:0016831)
0.1 5.1 GO:0035064 methylated histone binding(GO:0035064)
0.1 2.4 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 1.2 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 1.8 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1 19.7 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 0.9 GO:0008301 DNA binding, bending(GO:0008301)
0.1 1.7 GO:0005112 Notch binding(GO:0005112)
0.1 1.3 GO:0016651 oxidoreductase activity, acting on NAD(P)H(GO:0016651)
0.1 1.0 GO:0097602 cullin family protein binding(GO:0097602)
0.1 1.7 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 0.1 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.1 0.8 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 0.5 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.1 0.5 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.1 0.7 GO:0098918 structural constituent of postsynaptic specialization(GO:0098879) structural constituent of synapse(GO:0098918) structural constituent of postsynaptic density(GO:0098919)
0.1 0.3 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.0 3.3 GO:0008146 sulfotransferase activity(GO:0008146)
0.0 0.9 GO:0008373 sialyltransferase activity(GO:0008373)
0.0 0.7 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.0 0.5 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 1.4 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.6 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 1.8 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.5 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.7 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0 9.5 GO:0005549 odorant binding(GO:0005549)
0.0 0.6 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.1 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 1.4 GO:0008083 growth factor activity(GO:0008083)
0.0 0.0 GO:0045159 myosin II binding(GO:0045159)
0.0 0.0 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.7 GO:0001047 core promoter binding(GO:0001047)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 76.1 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
1.2 17.5 PID ALK2 PATHWAY ALK2 signaling events
1.0 17.5 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.8 3.2 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.7 29.5 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.7 9.5 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.7 14.1 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.7 41.6 PID BCR 5PATHWAY BCR signaling pathway
0.6 31.0 PID HNF3A PATHWAY FOXA1 transcription factor network
0.6 11.7 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.6 20.6 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.5 14.1 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.5 17.7 PID GLYPICAN 1PATHWAY Glypican 1 network
0.5 10.6 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.5 13.0 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.5 24.2 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.5 1.4 PID IL5 PATHWAY IL5-mediated signaling events
0.5 80.2 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.4 8.7 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.4 9.5 PID RAS PATHWAY Regulation of Ras family activation
0.3 0.7 PID S1P S1P3 PATHWAY S1P3 pathway
0.3 9.2 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.3 12.8 PID BMP PATHWAY BMP receptor signaling
0.3 6.9 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.2 4.1 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.2 53.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.2 10.4 PID AURORA B PATHWAY Aurora B signaling
0.2 5.9 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.2 14.1 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.2 10.3 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.2 7.5 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.2 5.6 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.2 5.8 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.2 7.3 PID LKB1 PATHWAY LKB1 signaling events
0.2 9.8 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.2 3.7 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.2 2.8 PID IL2 1PATHWAY IL2-mediated signaling events
0.2 6.7 PID ILK PATHWAY Integrin-linked kinase signaling
0.2 7.1 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.2 8.0 PID NOTCH PATHWAY Notch signaling pathway
0.2 4.5 PID CONE PATHWAY Visual signal transduction: Cones
0.1 1.8 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 3.8 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.1 3.2 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.1 3.1 PID TNF PATHWAY TNF receptor signaling pathway
0.1 3.0 PID ARF6 PATHWAY Arf6 signaling events
0.1 1.4 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.1 1.2 PID PI3KCI PATHWAY Class I PI3K signaling events
0.1 1.4 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.1 2.0 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 1.7 PID ATM PATHWAY ATM pathway
0.1 0.7 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.1 0.1 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.1 2.0 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.3 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.7 PID AR PATHWAY Coregulation of Androgen receptor activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 34.1 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
2.4 24.0 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
2.3 30.5 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
2.3 34.4 REACTOME COMMON PATHWAY Genes involved in Common Pathway
2.3 20.6 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
1.7 15.0 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
1.4 53.3 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
1.3 12.0 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
1.3 18.4 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
1.3 19.3 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
1.1 4.4 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
1.1 6.3 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
1.0 12.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
1.0 26.6 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.9 8.3 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.9 35.3 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.9 11.4 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.9 9.6 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.9 12.0 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.8 6.6 REACTOME DEFENSINS Genes involved in Defensins
0.8 4.0 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.8 54.9 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.7 22.2 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.6 8.1 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.6 12.9 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.6 9.6 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.5 10.3 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.5 9.4 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.5 5.7 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.5 17.6 REACTOME G1 PHASE Genes involved in G1 Phase
0.5 19.2 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.5 29.7 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.5 40.1 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.4 9.3 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.4 32.2 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.4 2.3 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.3 10.3 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.3 3.7 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.3 4.3 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.3 3.6 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.3 6.0 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.3 4.6 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.3 7.9 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.3 5.9 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.3 2.8 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.3 11.0 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.3 3.5 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.3 4.3 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.2 15.3 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.2 3.8 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.2 2.8 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.2 6.0 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.2 5.3 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.2 1.7 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.2 2.7 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.2 3.2 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.2 5.2 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.2 15.4 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.2 2.8 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.2 27.0 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.1 2.4 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.1 2.1 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 2.6 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 4.3 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.1 4.5 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.1 4.1 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 2.1 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 6.6 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 3.3 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 2.7 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 2.2 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.1 4.4 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 0.8 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.1 1.2 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.1 2.0 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 0.7 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 2.3 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.1 6.9 REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION Genes involved in 3' -UTR-mediated translational regulation
0.1 2.0 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.5 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 1.1 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 1.2 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.5 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 1.2 REACTOME TRAF6 MEDIATED INDUCTION OF NFKB AND MAP KINASES UPON TLR7 8 OR 9 ACTIVATION Genes involved in TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation
0.0 0.6 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.8 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.3 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis