Project

GSE53960: rat RNA-Seq transcriptomic Bodymap

Navigation
Downloads

Results for Prdm1

Z-value: 0.84

Motif logo

Transcription factors associated with Prdm1

Gene Symbol Gene ID Gene Info
ENSRNOG00000000323 PR/SET domain 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Prdm1rn6_v1_chr20_-_49486550_494865520.551.1e-26Click!

Activity profile of Prdm1 motif

Sorted Z-values of Prdm1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_215660492 37.04 ENSRNOT00000079442

chr5_-_58198782 34.86 ENSRNOT00000023951
C-C motif chemokine ligand 21
chr10_-_5251809 33.83 ENSRNOT00000085479
class II, major histocompatibility complex, transactivator
chr1_-_237910012 26.81 ENSRNOT00000023664
annexin A1
chr4_+_98337367 21.89 ENSRNOT00000042165

chr8_+_49713190 21.29 ENSRNOT00000022074
FXYD domain-containing ion transport regulator 2
chr20_-_1878126 21.16 ENSRNOT00000000995
ubiquitin D
chr13_-_109849632 20.76 ENSRNOT00000005085
activating transcription factor 3
chr13_+_48575091 20.69 ENSRNOT00000009838
peptidase M20 domain containing 1
chr2_+_209097927 17.23 ENSRNOT00000023807
DENN domain containing 2D
chr7_+_124460358 16.75 ENSRNOT00000014089
translocator protein
chr4_+_90990088 16.66 ENSRNOT00000030320
multimerin 1
chr6_-_24676524 15.38 ENSRNOT00000047853
calpain 13
chr3_+_6430201 15.08 ENSRNOT00000086352
collagen type V alpha 1 chain
chr2_-_238468435 14.92 ENSRNOT00000055537
rho guanine nucleotide exchange factor 38-like
chr3_-_160738927 14.71 ENSRNOT00000043470
antileukoproteinase-like 2
chr13_+_74410010 13.93 ENSRNOT00000079152
angiopoietin-like 1
chr3_+_16413080 13.64 ENSRNOT00000040386
Ig kappa chain V19-17-like
chr10_-_87067456 13.60 ENSRNOT00000014163
C-C motif chemokine receptor 7
chr15_-_51855325 13.38 ENSRNOT00000011663
PDZ and LIM domain 2
chr17_-_8429338 13.19 ENSRNOT00000016390
transforming growth factor, beta induced
chr11_-_37914983 12.62 ENSRNOT00000039876
myxovirus (influenza virus) resistance 1
chr5_-_58183017 12.48 ENSRNOT00000020982
C-C motif chemokine ligand 19
chr3_+_158997834 12.33 ENSRNOT00000000211
von Willebrand factor A domain-containing protein 5A
chr4_-_103024841 12.17 ENSRNOT00000090283

chrX_+_104684676 12.08 ENSRNOT00000083229
tenomodulin
chr3_-_7498555 12.00 ENSRNOT00000017725
BarH-like homeobox 1
chr7_-_117300662 11.97 ENSRNOT00000006376
poly (ADP-ribose) polymerase family, member 10
chr1_-_166677026 11.88 ENSRNOT00000026644
ENSRNOT00000076714
ADP-ribosyltransferase 2b
chr3_-_17081510 11.83 ENSRNOT00000063862

chr6_-_143195143 11.73 ENSRNOT00000081337

chr16_-_85306366 11.70 ENSRNOT00000089650
tumor necrosis factor superfamily member 13b
chr10_-_57064600 11.70 ENSRNOT00000032926
C-X-C motif chemokine ligand 16
chr2_-_149564113 11.55 ENSRNOT00000018628
immunoglobulin superfamily, member 10
chr14_+_6058544 11.25 ENSRNOT00000061267
ATP-binding cassette, subfamily G (WHITE), member 3-like 3
chr7_+_118685022 11.13 ENSRNOT00000089135
apolipoprotein L, 3
chr1_-_101236065 11.06 ENSRNOT00000066834
CD37 molecule
chr1_-_88193346 10.91 ENSRNOT00000078600
immortalization up-regulated protein-like
chr1_+_226634009 10.90 ENSRNOT00000028094
cytochrome b561 family, member A3
chr19_-_55367353 10.86 ENSRNOT00000091139
piezo-type mechanosensitive ion channel component 1
chr3_-_171286413 10.70 ENSRNOT00000008365
ENSRNOT00000081036
Z-DNA binding protein 1
chr5_+_173288447 10.69 ENSRNOT00000091205
ENSRNOT00000067252
matrix remodeling associated 8
chr4_+_149261044 10.63 ENSRNOT00000066670
C-X-C motif chemokine ligand 12
chr2_+_248398917 10.60 ENSRNOT00000045855
guanylate binding protein 1
chr8_+_42443442 10.56 ENSRNOT00000015986
von Willebrand factor A domain containing 5A
chr7_+_107695227 10.31 ENSRNOT00000009673
WNT1 inducible signaling pathway protein 1
chr20_+_3995544 10.23 ENSRNOT00000000527
transporter 2, ATP binding cassette subfamily B member
chr1_-_198577226 10.20 ENSRNOT00000055013
sialophorin
chr19_+_54060622 10.10 ENSRNOT00000023607
Gse1 coiled-coil protein
chr8_-_128026841 9.93 ENSRNOT00000018341
myeloid differentiation primary response 88
chr5_-_58950373 9.76 ENSRNOT00000060442
Cd72 molecule
chr13_-_89606326 9.76 ENSRNOT00000029179
Fc fragment of IgE receptor Ig
chrX_-_62690806 9.74 ENSRNOT00000018147
DNA polymerase alpha 1, catalytic subunit
chr9_-_76768770 9.64 ENSRNOT00000087779
ENSRNOT00000057849
IKAROS family zinc finger 2
chr9_+_68414339 9.61 ENSRNOT00000040778
par-3 family cell polarity regulator beta
chr1_-_217844957 9.59 ENSRNOT00000090653
anoctamin 1
chr20_+_3990820 9.30 ENSRNOT00000000528
proteasome subunit beta 8
chr16_-_48692476 9.28 ENSRNOT00000013118
interferon regulatory factor 2
chr2_+_243656579 9.25 ENSRNOT00000036993
alcohol dehydrogenase 1 (class I)
chr14_-_6541171 9.09 ENSRNOT00000042532
ENSRNOT00000087758
ATP-binding cassette, subfamily G (WHITE), member 3-like 1
chr8_+_14060394 9.03 ENSRNOT00000014827
single-pass membrane protein with coiled-coil domains 4
chr8_+_99880073 9.02 ENSRNOT00000010765
phospholipid scramblase 4
chr17_-_32661865 8.97 ENSRNOT00000022194
serpin family B member 9
chr9_+_98924134 8.97 ENSRNOT00000027597
twist family bHLH transcription factor 2
chr4_-_81968832 8.90 ENSRNOT00000016608
src kinase associated phosphoprotein 2
chr15_+_42489377 8.82 ENSRNOT00000064306
PDZ binding kinase
chrX_-_34794589 8.45 ENSRNOT00000008703
retinoic acid induced 2
chr4_-_103569159 8.28 ENSRNOT00000084036

chr15_+_34256071 8.25 ENSRNOT00000025887
proteasome activator subunit 1
chr17_-_44840131 8.23 ENSRNOT00000083417
histone cluster 1, H3b
chr3_+_22964230 8.07 ENSRNOT00000041813
ribosomal protein S20-like
chr1_+_41323194 7.99 ENSRNOT00000026350
estrogen receptor 1
chr2_-_235052464 7.97 ENSRNOT00000093512
uncharacterized LOC103691699
chr12_+_2180150 7.96 ENSRNOT00000001322
syntaxin binding protein 2
chr8_-_116469915 7.95 ENSRNOT00000024193
semaphorin 3F
chr20_+_12225202 7.84 ENSRNOT00000045315
collagen type XVIII alpha 1 chain
chrX_+_120624518 7.81 ENSRNOT00000007967
solute carrier family 6 member 14
chr9_-_1012450 7.81 ENSRNOT00000051449
ribosomal protein S20-like
chr13_+_51795867 7.66 ENSRNOT00000006747
ubiquitin-conjugating enzyme E2T
chr5_+_161889342 7.66 ENSRNOT00000040481
ribosomal protein S20-like
chr16_-_40555576 7.47 ENSRNOT00000015529
vascular endothelial growth factor C
chr18_+_79773608 7.45 ENSRNOT00000088484
zinc finger protein 516
chr5_-_59113773 7.43 ENSRNOT00000083129

chr1_-_101131012 7.36 ENSRNOT00000082283
ENSRNOT00000093498
ENSRNOT00000093559
fms-related tyrosine kinase 3 ligand
ribosomal protein L13A
chr20_+_248410 7.35 ENSRNOT00000049573
trimethyllysine hydroxylase, epsilon
chr20_-_3978845 7.33 ENSRNOT00000000532
proteasome subunit beta 9
chr5_+_157423213 7.33 ENSRNOT00000023431
transmembrane and coiled-coil domains 4
chr8_+_62341613 7.27 ENSRNOT00000066923
secretory carrier membrane protein 2
chr20_+_8484311 7.23 ENSRNOT00000050041
ribosomal protein S20-like
chr7_+_59349745 7.15 ENSRNOT00000085334
protein tyrosine phosphatase, receptor type, B
chr8_-_107952530 7.14 ENSRNOT00000052043
claudin 18
chr2_-_52282548 6.96 ENSRNOT00000033627
nicotinamide nucleotide transhydrogenase
chr17_+_69468427 6.93 ENSRNOT00000058413
similar to 20-alpha-hydroxysteroid dehydrogenase
chr4_+_67165883 6.80 ENSRNOT00000012280
RAB19, member RAS oncogene family
chr11_+_60336061 6.78 ENSRNOT00000084022
similar to OX-2 membrane glycoprotein precursor (MRC OX-2 antigen) (CD200 antigen)
chr17_+_32516679 6.64 ENSRNOT00000032707
serine (or cysteine) peptidase inhibitor, clade B, member 9d
chr4_-_161587222 6.56 ENSRNOT00000050834
TEA domain transcription factor 4
chr12_-_40686249 6.36 ENSRNOT00000042264
40S ribosomal protein S20-like
chr8_+_93439648 6.30 ENSRNOT00000043008
ribosomal protein S20-like
chr6_+_135866739 6.30 ENSRNOT00000013460
exocyst complex component 3-like 4
chr3_-_80842916 6.28 ENSRNOT00000033978
midkine
chr6_-_143702033 6.27 ENSRNOT00000051410

chr4_+_179398621 6.20 ENSRNOT00000049474
ENSRNOT00000067506
lymphoid-restricted membrane protein
chr13_+_99220510 6.17 ENSRNOT00000004519
transmembrane protein 63a
chr4_-_163214678 6.09 ENSRNOT00000091602
C-type lectin domain family 1, member A
chr19_-_25914689 6.05 ENSRNOT00000091994
ENSRNOT00000039354
nuclear factor 1 X
chr8_-_62616828 6.02 ENSRNOT00000068340
AT-rich interaction domain 3B
chr5_+_135687538 5.97 ENSRNOT00000091664

chr5_-_136053210 5.94 ENSRNOT00000025903
kinesin family member 2C
chr11_+_68105369 5.89 ENSRNOT00000046888
poly (ADP-ribose) polymerase family, member 14
chr3_+_28416954 5.75 ENSRNOT00000043533
kynureninase
chr18_-_30781292 5.74 ENSRNOT00000027125
TATA-box binding protein associated factor 7
chr8_+_48805684 5.63 ENSRNOT00000064041
B-cell CLL/lymphoma 9-like
chr1_+_128637049 5.61 ENSRNOT00000018639
tetratricopeptide repeat domain 23
chr6_-_1534488 5.52 ENSRNOT00000006824
CCAAT/enhancer binding protein zeta
chr13_-_102643223 5.51 ENSRNOT00000003155
H2.0-like homeobox
chr2_-_185444897 5.45 ENSRNOT00000016329
ribosomal protein S3a
chr3_-_114235933 5.44 ENSRNOT00000023939
dual oxidase 2
chr1_-_98521551 5.39 ENSRNOT00000081922
sialic acid binding Ig-like lectin 10
chr10_-_94652658 5.39 ENSRNOT00000017371
endoplasmic reticulum to nucleus signaling 1
chr20_+_8486265 5.38 ENSRNOT00000072213
40S ribosomal protein S20-like
chr3_-_37480984 5.30 ENSRNOT00000030373
N-myc (and STAT) interactor
chr8_-_115179191 5.29 ENSRNOT00000017224
poly (ADP-ribose) polymerase family, member 3
chr2_-_88763733 5.21 ENSRNOT00000059424
similar to solute carrier family 7 (cationic amino acid transporter, y+ system), member 12
chr10_+_57040267 5.11 ENSRNOT00000026207
arrestin, beta 2
chr16_+_75744786 5.07 ENSRNOT00000032368
XK related 5
chr4_-_21920651 5.06 ENSRNOT00000066211
transmembrane protein 243
chr7_+_144064931 5.04 ENSRNOT00000048504
proline rich 13
chr6_-_77421286 5.04 ENSRNOT00000011453
NK2 homeobox 1
chr1_+_201117630 5.04 ENSRNOT00000077908
transforming, acidic coiled-coil containing protein 2
chr1_-_87191588 5.04 ENSRNOT00000027998
rCG54286-like
chr1_-_217902473 5.02 ENSRNOT00000028329
anoctamin 1
chr1_-_91855983 4.98 ENSRNOT00000017172
regulator of G protein signaling 9 binding protein
chr2_-_198412350 4.93 ENSRNOT00000040210
histone H4-like
chr16_-_85305782 4.87 ENSRNOT00000067511
ENSRNOT00000076737
tumor necrosis factor superfamily member 13b
chr2_-_257376756 4.87 ENSRNOT00000065811
GIPC PDZ domain containing family, member 2
chr3_+_177397892 4.85 ENSRNOT00000078261

chr17_+_76079720 4.84 ENSRNOT00000073933
proline and serine rich 2
chr11_-_71695000 4.82 ENSRNOT00000073550
UBX domain protein 7
chr13_+_91334004 4.69 ENSRNOT00000041384
40S ribosomal protein S29
chr2_-_235852708 4.69 ENSRNOT00000009046
ENSRNOT00000005772
ribosomal protein L34
chrX_+_159158194 4.68 ENSRNOT00000043820
ENSRNOT00000001169
ENSRNOT00000083502
four and a half LIM domains 1
chr1_+_101517714 4.67 ENSRNOT00000028423
pleckstrin homology domain containing A4
chr10_+_57064482 4.63 ENSRNOT00000046807
zinc finger, MYND-type containing 15
chr4_+_56549739 4.62 ENSRNOT00000084597
hypoxia inducible lipid droplet-associated
chr8_+_116754178 4.49 ENSRNOT00000068295
ENSRNOT00000084429
ubiquitin-like modifier activating enzyme 7
chrX_-_19386541 4.43 ENSRNOT00000072722

chr5_+_104394119 4.43 ENSRNOT00000093557
ENSRNOT00000093462
ADAMTS-like 1
chr8_-_49573742 4.38 ENSRNOT00000021926
interleukin 10 receptor subunit alpha
chr6_-_125590049 4.36 ENSRNOT00000006371
tandem C2 domains, nuclear
chr11_+_64882288 4.29 ENSRNOT00000077727
phospholipase A1 member A
chr10_-_66482150 4.23 ENSRNOT00000048407
kinase suppressor of ras 1
chr17_+_4212890 4.23 ENSRNOT00000024467
testin gene
chr3_-_171957996 4.12 ENSRNOT00000036546
APC down-regulated 1 like
chr1_-_167708685 4.12 ENSRNOT00000092857
ENSRNOT00000024992
tripartite motif-containing 21
chr3_+_91191837 4.11 ENSRNOT00000006097
recombination activating 2
chr10_-_19652898 4.11 ENSRNOT00000009648
spindle apparatus coiled-coil protein 1
chr17_-_81002838 4.09 ENSRNOT00000089807
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6
chr3_-_95418679 4.08 ENSRNOT00000018074
reticulocalbin 1
chr4_-_113957774 4.01 ENSRNOT00000011921
INO80 complex subunit B
chr12_-_2786628 4.00 ENSRNOT00000001348
similar to DC-SIGN
chr4_-_114823500 3.99 ENSRNOT00000089870
INO80 complex subunit B
chr4_+_28989115 3.97 ENSRNOT00000075326
G protein subunit gamma 11
chr2_-_149563905 3.97 ENSRNOT00000086186
immunoglobulin superfamily, member 10
chr1_-_234704792 3.96 ENSRNOT00000017405
carnosine N-methyltransferase 1
chr2_+_208738132 3.95 ENSRNOT00000023972

chrX_-_123600890 3.95 ENSRNOT00000067942
septin 6
chr11_+_38035611 3.92 ENSRNOT00000087603
ENSRNOT00000002695
MX dynamin like GTPase 2
chr1_+_15062432 3.92 ENSRNOT00000016286
interferon gamma receptor 1
chr1_+_86972244 3.92 ENSRNOT00000036907
Ras and Rab interactor-like
chr13_+_52588917 3.92 ENSRNOT00000011999
pleckstrin homology-like domain, family A, member 3
chr2_+_60920257 3.92 ENSRNOT00000025170
C1q and tumor necrosis factor related protein 3
chr16_+_41079444 3.90 ENSRNOT00000015623
nei-like DNA glycosylase 3
chr19_+_60017746 3.88 ENSRNOT00000042623
par-3 family cell polarity regulator
chr7_+_144065650 3.87 ENSRNOT00000090695
proline rich 13
chr8_-_66863476 3.81 ENSRNOT00000018820
ribosomal protein lateral stalk subunit P1
chr1_-_167347490 3.79 ENSRNOT00000076499
ras homolog family member G
chr3_-_2123820 3.76 ENSRNOT00000086843
euchromatic histone lysine methyltransferase 1
chr15_-_12513931 3.72 ENSRNOT00000010103
ataxin 7
chr17_-_66295014 3.71 ENSRNOT00000023974
5-methyltetrahydrofolate-homocysteine methyltransferase
chr16_+_50016857 3.71 ENSRNOT00000035781
toll-like receptor 3
chr7_-_23953002 3.69 ENSRNOT00000047587
similar to 40S ribosomal protein S20
chr7_+_31784438 3.65 ENSRNOT00000010914
ENSRNOT00000010929
IKBKB interacting protein
chr20_-_5476193 3.64 ENSRNOT00000044975
TAP binding protein
chrX_-_159891326 3.63 ENSRNOT00000001154
RNA binding motif protein, X-linked
chr1_-_214159157 3.59 ENSRNOT00000091292
ENSRNOT00000022241
ribonuclease/angiogenin inhibitor 1
chr3_+_114236718 3.58 ENSRNOT00000024201
dual oxidase maturation factor 2
chr5_-_150653172 3.56 ENSRNOT00000072028
mediator complex subunit 18
chr5_+_135351816 3.55 ENSRNOT00000082602
intracisternal A particle-promoted polypeptide
chr17_-_66288202 3.51 ENSRNOT00000083172
5-methyltetrahydrofolate-homocysteine methyltransferase
chr10_-_5344121 3.45 ENSRNOT00000003479
nucleotide binding protein 1
chr8_-_126495347 3.42 ENSRNOT00000013467
C-x(9)-C motif containing 1
chr2_+_231941794 3.40 ENSRNOT00000091475

chr18_+_68408890 3.32 ENSRNOT00000039702
coiled-coil domain containing 68
chr4_+_87943152 3.32 ENSRNOT00000080536
vomeronasal 1 receptor 78
chr4_-_97784842 3.31 ENSRNOT00000007698
growth arrest and DNA-damage-inducible, alpha
chr9_-_54351339 3.30 ENSRNOT00000080522
signal transducer and activator of transcription 1
chr3_+_72191533 3.30 ENSRNOT00000044319
ubiquitin-conjugating enzyme E2L 6
chr9_-_65329066 3.28 ENSRNOT00000018284
peptidylprolyl isomerase like 3
chr16_-_60427474 3.26 ENSRNOT00000051720
protein phosphatase 1, regulatory subunit 3B

Network of associatons between targets according to the STRING database.

First level regulatory network of Prdm1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
12.2 60.9 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
8.1 32.3 GO:0045627 positive regulation of T-helper 1 cell differentiation(GO:0045627)
6.9 20.7 GO:0043605 cellular amide catabolic process(GO:0043605)
5.2 20.8 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
4.8 33.8 GO:0045343 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343) positive regulation of MHC class I biosynthetic process(GO:0045345)
4.0 12.0 GO:0010847 regulation of chromatin assembly(GO:0010847) protein poly-ADP-ribosylation(GO:0070212)
4.0 11.9 GO:0019677 NAD catabolic process(GO:0019677)
3.8 15.1 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
3.4 10.2 GO:0002481 antigen processing and presentation of exogenous peptide antigen via MHC class Ib(GO:0002477) antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent(GO:0002481) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway(GO:0002488) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent(GO:0002489) positive regulation of antigen processing and presentation of peptide antigen(GO:0002585) cytosol to ER transport(GO:0046967) peptide antigen transport(GO:0046968)
3.4 10.2 GO:0001807 regulation of type IV hypersensitivity(GO:0001807)
3.3 16.6 GO:0002636 positive regulation of germinal center formation(GO:0002636) B cell costimulation(GO:0031296)
3.3 9.9 GO:0072566 chemokine (C-X-C motif) ligand 1 production(GO:0072566) regulation of chemokine (C-X-C motif) ligand 1 production(GO:2000338)
3.3 9.8 GO:0002554 serotonin secretion by platelet(GO:0002554)
3.1 9.3 GO:0006117 acetaldehyde metabolic process(GO:0006117)
2.8 16.7 GO:0010266 response to vitamin B1(GO:0010266) maintenance of protein location in mitochondrion(GO:0072656)
2.8 11.1 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
2.7 10.7 GO:0060857 establishment of glial blood-brain barrier(GO:0060857)
2.7 10.6 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
2.6 21.2 GO:0070842 aggresome assembly(GO:0070842)
2.5 7.5 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
2.4 9.7 GO:0006272 leading strand elongation(GO:0006272)
2.4 7.1 GO:2001205 negative regulation of osteoclast development(GO:2001205)
2.0 12.1 GO:0035990 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
2.0 8.0 GO:1990375 baculum development(GO:1990375)
2.0 17.6 GO:0003374 dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374)
1.9 7.7 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
1.8 7.4 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
1.8 7.3 GO:1901423 response to benzene(GO:1901423)
1.8 5.4 GO:0042335 cuticle development(GO:0042335) hypophysis morphogenesis(GO:0048850)
1.8 9.0 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
1.8 10.6 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
1.8 5.3 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
1.8 5.3 GO:1990166 protein localization to site of double-strand break(GO:1990166)
1.6 14.6 GO:0015705 iodide transport(GO:0015705)
1.6 7.8 GO:0032020 ISG15-protein conjugation(GO:0032020)
1.6 10.9 GO:0033634 positive regulation of integrin activation(GO:0033625) positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
1.5 4.6 GO:0035425 autocrine signaling(GO:0035425)
1.4 7.2 GO:1904640 response to methionine(GO:1904640)
1.4 5.8 GO:0019805 quinolinate biosynthetic process(GO:0019805)
1.3 8.0 GO:0097490 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491)
1.3 5.1 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
1.3 6.3 GO:0030421 defecation(GO:0030421)
1.3 21.3 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
1.2 7.4 GO:0045329 carnitine biosynthetic process(GO:0045329)
1.2 3.6 GO:0002397 MHC class I protein complex assembly(GO:0002397)
1.2 3.5 GO:0072697 protein localization to cell cortex(GO:0072697)
1.1 6.5 GO:0045080 positive regulation of chemokine biosynthetic process(GO:0045080)
1.1 3.2 GO:1903972 regulation of macrophage colony-stimulating factor signaling pathway(GO:1902226) regulation of response to macrophage colony-stimulating factor(GO:1903969) regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903972) microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
1.1 10.7 GO:0060340 positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
1.0 4.1 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
1.0 9.0 GO:0061303 cornea development in camera-type eye(GO:0061303)
1.0 5.9 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.9 5.4 GO:0036289 peptidyl-serine autophosphorylation(GO:0036289)
0.8 5.0 GO:0021759 globus pallidus development(GO:0021759)
0.8 3.3 GO:0034240 negative regulation of macrophage fusion(GO:0034240)
0.8 4.1 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.8 3.2 GO:1902623 leukocyte chemotaxis involved in inflammatory response(GO:0002232) negative regulation of neutrophil migration(GO:1902623)
0.8 11.7 GO:0010818 T cell chemotaxis(GO:0010818)
0.8 4.7 GO:0046292 formaldehyde metabolic process(GO:0046292)
0.8 3.8 GO:1904401 cellular response to Thyroid stimulating hormone(GO:1904401)
0.8 2.3 GO:1901740 negative regulation of myoblast fusion(GO:1901740)
0.8 20.3 GO:0006855 drug transmembrane transport(GO:0006855)
0.7 2.2 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
0.7 7.8 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.7 3.9 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.6 3.9 GO:0003383 apical constriction(GO:0003383)
0.6 1.9 GO:0015722 canalicular bile acid transport(GO:0015722)
0.6 10.3 GO:0061051 positive regulation of cell growth involved in cardiac muscle cell development(GO:0061051)
0.6 2.5 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.5 1.6 GO:1990091 sodium-dependent self proteolysis(GO:1990091)
0.5 8.0 GO:0043312 neutrophil degranulation(GO:0043312)
0.5 4.1 GO:0090086 negative regulation of protein deubiquitination(GO:0090086)
0.5 3.6 GO:2000609 regulation of thyroid hormone generation(GO:2000609)
0.5 9.0 GO:0017121 phospholipid scrambling(GO:0017121)
0.5 1.5 GO:1905006 positive regulation of activation-induced cell death of T cells(GO:0070237) negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation(GO:1905006)
0.4 6.3 GO:0051601 exocyst localization(GO:0051601)
0.4 6.6 GO:1902459 positive regulation of stem cell population maintenance(GO:1902459)
0.4 6.1 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.4 2.6 GO:0060723 regulation of spongiotrophoblast cell proliferation(GO:0060721) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.4 2.1 GO:1900425 negative regulation of defense response to bacterium(GO:1900425)
0.4 5.0 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.4 2.3 GO:0036438 maintenance of lens transparency(GO:0036438)
0.4 3.8 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.4 1.9 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.4 1.1 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.3 5.5 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.3 2.3 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.3 8.3 GO:0019884 antigen processing and presentation of exogenous antigen(GO:0019884)
0.3 1.6 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.3 1.8 GO:0006449 regulation of translational termination(GO:0006449)
0.3 4.9 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.3 4.1 GO:0034501 protein localization to kinetochore(GO:0034501)
0.3 1.1 GO:1902994 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985) regulation of phospholipid efflux(GO:1902994) positive regulation of phospholipid efflux(GO:1902995)
0.3 1.4 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
0.3 3.3 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.3 2.6 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.3 1.3 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.2 5.0 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.2 0.7 GO:0002462 tolerance induction to nonself antigen(GO:0002462)
0.2 5.7 GO:0035067 negative regulation of histone acetylation(GO:0035067)
0.2 1.6 GO:0030397 membrane disassembly(GO:0030397) nuclear envelope disassembly(GO:0051081)
0.2 6.5 GO:1900027 regulation of ruffle assembly(GO:1900027)
0.2 0.6 GO:0006552 leucine catabolic process(GO:0006552)
0.2 2.1 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.2 3.0 GO:1902358 oxalate transport(GO:0019532) sulfate transmembrane transport(GO:1902358)
0.2 15.5 GO:0042246 tissue regeneration(GO:0042246)
0.2 0.5 GO:2000567 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.2 0.5 GO:1905243 response to 3,3',5-triiodo-L-thyronine(GO:1905242) cellular response to 3,3',5-triiodo-L-thyronine(GO:1905243)
0.2 3.7 GO:0016578 histone deubiquitination(GO:0016578)
0.2 2.2 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.2 5.5 GO:0010718 positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.1 7.4 GO:0060612 adipose tissue development(GO:0060612)
0.1 5.2 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.1 0.7 GO:0010694 positive regulation of alkaline phosphatase activity(GO:0010694)
0.1 1.2 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.1 5.2 GO:1902475 L-alpha-amino acid transmembrane transport(GO:1902475)
0.1 6.1 GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032435)
0.1 4.7 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.1 12.5 GO:0030901 midbrain development(GO:0030901)
0.1 0.8 GO:0034201 response to oleic acid(GO:0034201)
0.1 0.9 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.1 14.0 GO:0042157 lipoprotein metabolic process(GO:0042157)
0.1 14.9 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.1 1.7 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.1 7.6 GO:0019882 antigen processing and presentation(GO:0019882)
0.1 3.9 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.1 1.1 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.1 1.6 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.1 1.7 GO:0030449 regulation of complement activation(GO:0030449)
0.1 14.3 GO:0007596 blood coagulation(GO:0007596)
0.1 3.9 GO:0006284 base-excision repair(GO:0006284)
0.1 1.6 GO:0097286 iron ion import(GO:0097286)
0.1 3.3 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 0.5 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.1 16.3 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.1 0.7 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.1 2.4 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.0 1.7 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.4 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.0 30.8 GO:0006412 translation(GO:0006412)
0.0 8.0 GO:0030198 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0 2.3 GO:0008542 visual learning(GO:0008542)
0.0 0.6 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 4.0 GO:0006338 chromatin remodeling(GO:0006338)
0.0 0.2 GO:0071000 response to magnetism(GO:0071000)
0.0 4.0 GO:0006518 peptide metabolic process(GO:0006518)
0.0 3.5 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.9 GO:0031648 protein destabilization(GO:0031648)
0.0 0.1 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.0 1.0 GO:0019098 reproductive behavior(GO:0019098)
0.0 0.9 GO:0060976 coronary vasculature development(GO:0060976)
0.0 3.6 GO:0007286 spermatid development(GO:0007286)
0.0 1.2 GO:0030500 regulation of bone mineralization(GO:0030500)
0.0 1.8 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209) negative regulation of sequestering of calcium ion(GO:0051283)
0.0 3.2 GO:0015992 proton transport(GO:0015992)
0.0 0.2 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.0 GO:0032741 positive regulation of interleukin-18 production(GO:0032741)
0.0 4.0 GO:0008380 RNA splicing(GO:0008380)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
6.9 20.8 GO:1990622 CHOP-ATF3 complex(GO:1990622)
3.8 15.1 GO:0005588 collagen type V trimer(GO:0005588)
3.0 26.8 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
2.8 8.3 GO:0008537 proteasome activator complex(GO:0008537)
2.7 10.6 GO:0020005 symbiont-containing vacuole membrane(GO:0020005)
2.6 15.8 GO:1990111 spermatoproteasome complex(GO:1990111)
2.0 13.9 GO:0042825 TAP complex(GO:0042825)
1.8 21.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
1.3 5.4 GO:1990630 IRE1-RACK1-PP2A complex(GO:1990630)
1.2 9.7 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
1.1 3.2 GO:1990682 CSF1-CSF1R complex(GO:1990682)
1.0 8.0 GO:0044194 cytolytic granule(GO:0044194) tertiary granule(GO:0070820)
0.9 7.4 GO:0097452 GAIT complex(GO:0097452)
0.9 7.8 GO:0098651 basement membrane collagen trimer(GO:0098651)
0.8 8.0 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.8 3.0 GO:0070876 SOSS complex(GO:0070876)
0.7 3.6 GO:0044530 supraspliceosomal complex(GO:0044530)
0.7 4.3 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.7 10.2 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.6 1.9 GO:0046691 intracellular canaliculus(GO:0046691)
0.6 5.7 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.6 1.8 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.6 10.9 GO:0031258 lamellipodium membrane(GO:0031258)
0.6 10.3 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.5 4.8 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.4 6.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.4 21.2 GO:0016235 aggresome(GO:0016235)
0.4 2.1 GO:0097209 epidermal lamellar body(GO:0097209)
0.3 11.1 GO:0001772 immunological synapse(GO:0001772)
0.3 3.3 GO:0042587 glycogen granule(GO:0042587)
0.3 3.9 GO:0043219 lateral loop(GO:0043219)
0.3 32.7 GO:0016605 PML body(GO:0016605)
0.3 7.3 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.3 6.3 GO:0000145 exocyst(GO:0000145)
0.2 4.0 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.2 2.3 GO:0042555 MCM complex(GO:0042555)
0.2 15.8 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.2 5.3 GO:0035861 site of double-strand break(GO:0035861)
0.2 13.4 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.2 5.9 GO:0035371 microtubule plus-end(GO:0035371)
0.2 4.9 GO:0000788 nuclear nucleosome(GO:0000788)
0.2 4.3 GO:0002080 acrosomal membrane(GO:0002080)
0.2 6.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.2 52.8 GO:0009897 external side of plasma membrane(GO:0009897)
0.2 17.2 GO:0005604 basement membrane(GO:0005604)
0.2 1.3 GO:0000796 condensin complex(GO:0000796)
0.2 2.5 GO:0005686 U2 snRNP(GO:0005686)
0.2 3.2 GO:0019013 viral nucleocapsid(GO:0019013)
0.2 0.8 GO:0030689 Noc complex(GO:0030689)
0.1 36.1 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.1 3.9 GO:0005581 collagen trimer(GO:0005581)
0.1 1.9 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1 17.6 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.1 16.7 GO:0031012 extracellular matrix(GO:0031012)
0.1 2.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 8.5 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 1.6 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 4.1 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 8.8 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.1 5.3 GO:0031902 late endosome membrane(GO:0031902)
0.1 4.6 GO:0005811 lipid particle(GO:0005811)
0.1 0.7 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 1.1 GO:0001891 phagocytic cup(GO:0001891)
0.1 2.1 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 18.0 GO:0005925 focal adhesion(GO:0005925)
0.1 8.4 GO:0032993 protein-DNA complex(GO:0032993)
0.1 1.2 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.1 14.4 GO:0016324 apical plasma membrane(GO:0016324)
0.0 3.5 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 3.3 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 2.9 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.5 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.5 GO:0036038 MKS complex(GO:0036038)
0.0 1.4 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 3.9 GO:0001726 ruffle(GO:0001726)
0.0 1.8 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 33.6 GO:0005730 nucleolus(GO:0005730)
0.0 8.2 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 5.6 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 15.6 GO:0031966 mitochondrial membrane(GO:0031966)
0.0 3.5 GO:0005814 centriole(GO:0005814)
0.0 1.2 GO:0016592 mediator complex(GO:0016592)
0.0 1.5 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 1.5 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 6.3 GO:0000785 chromatin(GO:0000785)
0.0 3.3 GO:0005635 nuclear envelope(GO:0005635)
0.0 10.0 GO:0005615 extracellular space(GO:0005615)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
5.4 26.8 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
4.2 12.5 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
3.7 14.6 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
3.4 10.2 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433) tapasin binding(GO:0046980)
3.3 9.9 GO:0070976 TIR domain binding(GO:0070976)
2.7 10.7 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
2.7 10.6 GO:0019002 GMP binding(GO:0019002)
1.9 5.8 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
1.9 5.7 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
1.7 5.1 GO:0031762 follicle-stimulating hormone receptor binding(GO:0031762) type 2A serotonin receptor binding(GO:0031826)
1.7 8.3 GO:0061133 endopeptidase activator activity(GO:0061133)
1.6 57.2 GO:0008009 chemokine activity(GO:0008009)
1.6 9.8 GO:0019767 IgE receptor activity(GO:0019767)
1.6 8.0 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798)
1.6 8.0 GO:0030348 syntaxin-3 binding(GO:0030348)
1.5 9.3 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
1.5 21.3 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
1.5 11.9 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
1.4 9.7 GO:0003896 DNA primase activity(GO:0003896)
1.4 13.6 GO:0019957 C-C chemokine binding(GO:0019957)
1.4 25.8 GO:0070628 proteasome binding(GO:0070628)
1.2 13.4 GO:0032036 myosin heavy chain binding(GO:0032036)
1.2 3.6 GO:0046979 TAP binding(GO:0046977) TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
1.2 10.9 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
1.1 23.1 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
1.1 3.3 GO:0042296 ISG15 transferase activity(GO:0042296)
1.1 15.1 GO:0048407 platelet-derived growth factor binding(GO:0048407)
1.1 3.2 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.9 7.2 GO:0031419 S-methyltransferase activity(GO:0008172) cobalamin binding(GO:0031419)
0.9 20.3 GO:0017127 cholesterol transporter activity(GO:0017127)
0.9 4.4 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.7 4.3 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.7 17.0 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.7 2.0 GO:0071208 histone pre-mRNA DCP binding(GO:0071208) U7 snRNA binding(GO:0071209)
0.6 9.0 GO:0042609 CD4 receptor binding(GO:0042609)
0.6 7.5 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.6 8.0 GO:0045499 chemorepellent activity(GO:0045499)
0.6 4.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.6 5.4 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.6 3.6 GO:0008428 ribonuclease inhibitor activity(GO:0008428)
0.6 2.3 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.6 5.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.6 3.9 GO:0000405 bubble DNA binding(GO:0000405)
0.5 1.6 GO:0046592 polyamine oxidase activity(GO:0046592)
0.5 2.0 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.5 41.3 GO:0033613 activating transcription factor binding(GO:0033613)
0.4 5.0 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.4 4.5 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.4 16.8 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.4 10.3 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.4 2.6 GO:0015119 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.4 3.3 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.4 3.3 GO:0043515 kinetochore binding(GO:0043515)
0.4 5.4 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.4 1.8 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.3 8.9 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.3 8.0 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.3 7.4 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.3 2.3 GO:1990446 U1 snRNP binding(GO:1990446)
0.3 5.9 GO:0051010 microtubule plus-end binding(GO:0051010)
0.3 9.0 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.3 1.5 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.3 20.7 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.3 1.7 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.3 9.7 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.2 7.7 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.2 4.7 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.2 0.7 GO:0050682 AF-2 domain binding(GO:0050682)
0.2 13.2 GO:0050840 extracellular matrix binding(GO:0050840)
0.2 60.0 GO:0003735 structural constituent of ribosome(GO:0003735)
0.2 1.1 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.2 3.0 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.2 1.7 GO:0001846 opsonin binding(GO:0001846)
0.2 7.9 GO:0030544 Hsp70 protein binding(GO:0030544)
0.2 0.8 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.2 2.4 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.2 3.9 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.2 16.7 GO:0005496 steroid binding(GO:0005496)
0.2 0.5 GO:0023029 MHC class Ib protein binding(GO:0023029)
0.2 4.1 GO:0008373 sialyltransferase activity(GO:0008373)
0.2 14.9 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.2 20.8 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 1.9 GO:0015250 water channel activity(GO:0015250)
0.1 1.1 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.1 14.5 GO:0003697 single-stranded DNA binding(GO:0003697)
0.1 0.5 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.1 4.3 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1 3.4 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 2.3 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 7.0 GO:0050661 NADP binding(GO:0050661)
0.1 3.5 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.1 40.5 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.1 30.9 GO:0003924 GTPase activity(GO:0003924)
0.1 18.4 GO:0061135 endopeptidase inhibitor activity(GO:0004866) endopeptidase regulator activity(GO:0061135)
0.1 2.4 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 0.7 GO:0001848 complement binding(GO:0001848)
0.1 1.6 GO:0005521 lamin binding(GO:0005521)
0.1 3.3 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.1 5.2 GO:0015297 antiporter activity(GO:0015297)
0.1 4.4 GO:0030276 clathrin binding(GO:0030276)
0.1 2.1 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 2.9 GO:0016409 palmitoyltransferase activity(GO:0016409)
0.1 2.2 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.1 3.7 GO:0003725 double-stranded RNA binding(GO:0003725)
0.1 0.9 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.9 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.1 4.2 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.1 4.8 GO:0043130 ubiquitin binding(GO:0043130)
0.1 6.0 GO:0001076 transcription factor activity, RNA polymerase II transcription factor binding(GO:0001076)
0.0 3.6 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 2.6 GO:0048029 monosaccharide binding(GO:0048029)
0.0 1.1 GO:0016755 transferase activity, transferring amino-acyl groups(GO:0016755)
0.0 0.6 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 3.7 GO:0019955 cytokine binding(GO:0019955)
0.0 6.7 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.0 0.2 GO:0071253 connexin binding(GO:0071253)
0.0 1.6 GO:0038024 cargo receptor activity(GO:0038024)
0.0 11.7 GO:0005198 structural molecule activity(GO:0005198)
0.0 0.9 GO:0042605 peptide antigen binding(GO:0042605)
0.0 5.2 GO:0030246 carbohydrate binding(GO:0030246)
0.0 2.5 GO:0004540 ribonuclease activity(GO:0004540)
0.0 0.5 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 9.3 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 1.3 GO:0008201 heparin binding(GO:0008201)
0.0 0.8 GO:0005178 integrin binding(GO:0005178)
0.0 0.1 GO:0032794 GTPase activating protein binding(GO:0032794)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 14.9 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.7 10.0 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.7 7.5 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.6 13.6 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.5 22.9 NABA COLLAGENS Genes encoding collagen proteins
0.4 16.9 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.4 11.4 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.4 8.0 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.4 24.5 PID ATF2 PATHWAY ATF-2 transcription factor network
0.3 44.8 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.2 48.1 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.2 5.0 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.2 52.7 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.2 7.2 PID AURORA B PATHWAY Aurora B signaling
0.2 9.8 PID BCR 5PATHWAY BCR signaling pathway
0.2 7.7 PID FANCONI PATHWAY Fanconi anemia pathway
0.1 5.5 PID IL12 2PATHWAY IL12-mediated signaling events
0.1 7.3 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.1 5.9 PID IL4 2PATHWAY IL4-mediated signaling events
0.1 9.7 PID E2F PATHWAY E2F transcription factor network
0.1 4.2 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.1 5.0 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 6.5 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.1 1.6 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 2.6 PID TNF PATHWAY TNF receptor signaling pathway
0.1 7.6 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.1 1.2 PID ARF 3PATHWAY Arf1 pathway
0.1 1.7 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 1.2 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 4.9 NABA MATRISOME ASSOCIATED Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors
0.0 0.8 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.2 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 83.3 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
1.1 10.0 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
1.1 63.7 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.8 14.4 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.8 26.8 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.7 20.8 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.7 11.8 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.7 8.9 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.7 9.8 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.6 5.8 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.6 7.5 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.6 9.7 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.5 20.1 REACTOME AMYLOIDS Genes involved in Amyloids
0.4 16.2 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.4 7.0 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.4 10.2 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.3 11.0 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.3 12.9 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.3 7.7 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.3 9.1 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.3 7.8 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.3 7.8 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.2 24.4 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.2 6.6 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.2 4.1 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.2 2.3 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.2 5.9 REACTOME KINESINS Genes involved in Kinesins
0.2 2.0 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.2 26.8 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.2 8.0 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.2 1.9 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 1.7 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 1.2 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 5.6 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.1 5.4 REACTOME UNFOLDED PROTEIN RESPONSE Genes involved in Unfolded Protein Response
0.1 1.6 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 1.2 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 0.8 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.1 6.9 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 1.7 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1 2.3 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.1 1.1 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 3.0 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.6 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.1 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.2 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 1.4 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 1.2 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.5 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction