ISMARA results: Ppara

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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Ppara

Z-value: 1.80

Motif logo

Transcription factors associated with Ppara

Gene Symbol	Gene ID	Gene Info
Ppara NCBI RGD Ensembl	ENSRNOG00000021463	peroxisome proliferator activated receptor alpha

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Ppara	rn6_v1_chr7_+_126619196_126619196	0.03	5.5e-01	Click!

Activity profile of Ppara motif

Sorted Z-values of Ppara motif

Top targets:

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr17_-_66397653 Show fit	106.59	ENSRNOT00000024098	Actn2 NCBI RGD Ensembl Show fit	actinin alpha 2
chr10_+_11240138 Show fit	96.61	ENSRNOT00000048687	Srl NCBI RGD Ensembl Show fit	sarcalumenin
chr8_-_130429132 Show fit	86.33	ENSRNOT00000026261	Hhatl NCBI RGD Ensembl Show fit	hedgehog acyltransferase-like
chr8_-_84522588 Show fit	83.20	ENSRNOT00000076213	Mlip NCBI RGD Ensembl Show fit	muscular LMNA-interacting protein
chr15_+_33606124 Show fit	76.61	ENSRNOT00000065210	AC115371.1 NCBI RGD Ensembl Show fit
chr19_-_56677084 Show fit	74.11	ENSRNOT00000024084	Acta1 NCBI RGD Ensembl Show fit	actin, alpha 1, skeletal muscle
chr7_-_80796670 Show fit	73.16	ENSRNOT00000010539	Abra NCBI RGD Ensembl Show fit	actin-binding Rho activating protein
chr10_-_8498422 Show fit	61.33	ENSRNOT00000082332	Rbfox1 NCBI RGD Ensembl Show fit	RNA binding protein, fox-1 homolog 1
chr8_-_84506328 Show fit	60.26	ENSRNOT00000064754	Mlip NCBI RGD Ensembl Show fit	muscular LMNA-interacting protein
chr18_+_73564247 Show fit	53.41	ENSRNOT00000077679 ENSRNOT00000035317	St8sia5 NCBI RGD Ensembl Show fit	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
chr17_+_32973695 Show fit	52.70	ENSRNOT00000065674	RGD1565323 NCBI RGD Ensembl Show fit	similar to OTTMUSP00000000621
chr1_+_153861948 Show fit	51.02	ENSRNOT00000087067	Me3 NCBI RGD Ensembl Show fit	malic enzyme 3
chr3_-_113525864 Show fit	48.43	ENSRNOT00000046659	Frmd5 NCBI RGD Ensembl Show fit	FERM domain containing 5
chr14_+_26662965 Show fit	47.68	ENSRNOT00000002621	Tecrl NCBI RGD Ensembl Show fit	trans-2,3-enoyl-CoA reductase-like
chr9_+_47536824 Show fit	46.83	ENSRNOT00000049349	Tmem182 NCBI RGD Ensembl Show fit	transmembrane protein 182
chr3_+_168345152 Show fit	44.71	ENSRNOT00000017654	Dok5 NCBI RGD Ensembl Show fit	docking protein 5
chr5_-_160179978 Show fit	44.06	ENSRNOT00000022820	Slc25a34 NCBI RGD Ensembl Show fit	solute carrier family 25, member 34
chr3_-_159775643 Show fit	43.86	ENSRNOT00000010939	Jph2 NCBI RGD Ensembl Show fit	junctophilin 2
chr3_+_113257688 Show fit	43.56	ENSRNOT00000019320	Map1a NCBI RGD Ensembl Show fit	microtubule-associated protein 1A
chr8_+_48406260 Show fit	42.71	ENSRNOT00000009975	Usp2 NCBI RGD Ensembl Show fit	ubiquitin specific peptidase 2
chr1_-_89488223 Show fit	41.95	ENSRNOT00000028624	Fxyd1 NCBI RGD Ensembl Show fit	FXYD domain-containing ion transport regulator 1
chr15_-_27819376 Show fit	41.91	ENSRNOT00000067400	A930018M24Rik NCBI RGD Ensembl Show fit	RIKEN cDNA A930018M24 gene
chr16_-_10941414 Show fit	41.71	ENSRNOT00000086627 ENSRNOT00000085414 ENSRNOT00000081631 ENSRNOT00000087521 ENSRNOT00000083623	Ldb3 NCBI RGD Ensembl Show fit	LIM domain binding 3
chr9_+_81816872 Show fit	40.88	ENSRNOT00000041407	Plcd4 NCBI RGD Ensembl Show fit	phospholipase C, delta 4
chr1_+_153861569 Show fit	39.36	ENSRNOT00000023329	Me3 NCBI RGD Ensembl Show fit	malic enzyme 3
chr6_+_23337571 Show fit	39.28	ENSRNOT00000011832	RGD1304963 NCBI RGD Ensembl Show fit	similar to hypothetical protein MGC38716
chr12_-_5822874 Show fit	39.14	ENSRNOT00000075920	Fry NCBI RGD Ensembl Show fit	FRY microtubule binding protein
chr19_+_50848736 Show fit	39.11	ENSRNOT00000077053	Cdh13 NCBI RGD Ensembl Show fit	cadherin 13
chrX_-_40086870 Show fit	38.43	ENSRNOT00000010027	Smpx NCBI RGD Ensembl Show fit	small muscle protein, X-linked
chr10_-_109729019 Show fit	38.18	ENSRNOT00000054959	Ppp1r27 NCBI RGD Ensembl Show fit	protein phosphatase 1, regulatory subunit 27
chr4_+_64088900 Show fit	38.12	ENSRNOT00000075341	Chrm2 NCBI RGD Ensembl Show fit	cholinergic receptor, muscarinic 2
chr14_-_83741969 Show fit	37.75	ENSRNOT00000026293	Inpp5j NCBI RGD Ensembl Show fit	inositol polyphosphate-5-phosphatase J
chr6_+_147876237 Show fit	36.99	ENSRNOT00000056649	Tmem196 NCBI RGD Ensembl Show fit	transmembrane protein 196
chr10_+_39655455 Show fit	36.90	ENSRNOT00000058817	Acsl6 NCBI RGD Ensembl Show fit	acyl-CoA synthetase long-chain family member 6
chr5_+_90338795 Show fit	35.86	ENSRNOT00000077864 ENSRNOT00000058882	LOC298139 NCBI RGD Ensembl Show fit	similar to RIKEN cDNA 2310003M01
chr7_+_11356118 Show fit	35.70	ENSRNOT00000041325	Atcay NCBI RGD Ensembl Show fit	ATCAY, caytaxin
chr1_-_81881549 Show fit	34.98	ENSRNOT00000027497	Atp1a3 NCBI RGD Ensembl Show fit	ATPase Na+/K+ transporting subunit alpha 3
chr3_+_58632476 Show fit	34.71	ENSRNOT00000010630	Rapgef4 NCBI RGD Ensembl Show fit	Rap guanine nucleotide exchange factor 4
chr1_+_224882439 Show fit	34.46	ENSRNOT00000024785	Chrm1 NCBI RGD Ensembl Show fit	cholinergic receptor, muscarinic 1
chr4_-_157331905 Show fit	34.43	ENSRNOT00000020647	Tpi1 NCBI RGD Ensembl Show fit	triosephosphate isomerase 1
chr9_+_20213776 Show fit	33.81	ENSRNOT00000071439	LOC100911515 NCBI RGD Ensembl Show fit	triosephosphate isomerase-like
chr6_+_28515025 Show fit	33.70	ENSRNOT00000088033 ENSRNOT00000005317 ENSRNOT00000081141	Dnajc27 NCBI RGD Ensembl Show fit	DnaJ heat shock protein family (Hsp40) member C27
chr12_-_30566032 Show fit	33.50	ENSRNOT00000093378	Gbas NCBI RGD Ensembl Show fit	glioblastoma amplified sequence
chr10_-_38782419 Show fit	33.05	ENSRNOT00000073964	Uqcrq NCBI RGD Ensembl Show fit	ubiquinol-cytochrome c reductase, complex III subunit VII
chr12_-_44174583 Show fit	32.00	ENSRNOT00000001490	Tesc NCBI RGD Ensembl Show fit	tescalcin
chr10_+_27973681 Show fit	31.85	ENSRNOT00000004970	Gabrb2 NCBI RGD Ensembl Show fit	gamma-aminobutyric acid type A receptor beta 2 subunit
chr5_+_173640780 Show fit	31.82	ENSRNOT00000027476	Perm1 NCBI RGD Ensembl Show fit	PPARGC1 and ESRR induced regulator, muscle 1
chr1_+_72882806 Show fit	31.58	ENSRNOT00000024640	Tnni3 NCBI RGD Ensembl Show fit	troponin I3, cardiac type
chr5_+_118743632 Show fit	31.43	ENSRNOT00000013785	Pgm1 NCBI RGD Ensembl Show fit	phosphoglucomutase 1
chr5_-_25584278 Show fit	31.34	ENSRNOT00000090579 ENSRNOT00000090376	Pdp1 NCBI RGD Ensembl Show fit	pyruvate dehyrogenase phosphatase catalytic subunit 1
chr1_-_143398093 Show fit	30.98	ENSRNOT00000078916	Fsd2 NCBI RGD Ensembl Show fit	fibronectin type III and SPRY domain containing 2
chr1_-_263269762 Show fit	30.95	ENSRNOT00000022309	Got1 NCBI RGD Ensembl Show fit	glutamic-oxaloacetic transaminase 1
chr9_-_92291220 Show fit	30.74	ENSRNOT00000093357	Dner NCBI RGD Ensembl Show fit	delta/notch-like EGF repeat containing
chr1_+_37507276 Show fit	30.71	ENSRNOT00000047627	Adcy2 NCBI RGD Ensembl Show fit	adenylate cyclase 2
chr14_+_60764409 Show fit	30.23	ENSRNOT00000005168	Lgi2 NCBI RGD Ensembl Show fit	leucine-rich repeat LGI family, member 2
chr13_+_52625441 Show fit	29.79	ENSRNOT00000012095	Tnni1 NCBI RGD Ensembl Show fit	troponin I1, slow skeletal type
chr10_-_102289837 Show fit	29.57	ENSRNOT00000044922	AABR07030729.1 NCBI RGD Ensembl Show fit
chr1_-_170404056 Show fit	29.23	ENSRNOT00000024402	Apbb1 NCBI RGD Ensembl Show fit	amyloid beta precursor protein binding family B member 1
chr10_-_27179900 Show fit	28.80	ENSRNOT00000082445	Gabrg2 NCBI RGD Ensembl Show fit	gamma-aminobutyric acid type A receptor gamma 2 subunit
chr6_+_126434226 Show fit	28.66	ENSRNOT00000090857	Chga NCBI RGD Ensembl Show fit	chromogranin A
chr4_-_55398941 Show fit	28.30	ENSRNOT00000075324	Grm8 NCBI RGD Ensembl Show fit	glutamate metabotropic receptor 8
chr7_+_121311024 Show fit	28.25	ENSRNOT00000092260 ENSRNOT00000023066 ENSRNOT00000081377	Syngr1 NCBI RGD Ensembl Show fit	synaptogyrin 1
chr18_+_74156553 Show fit	27.76	ENSRNOT00000022892	Atp5a1 NCBI RGD Ensembl Show fit	ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
chr20_+_28572242 Show fit	27.72	ENSRNOT00000072485	Sh3rf3 NCBI RGD Ensembl Show fit	SH3 domain containing ring finger 3
chr1_+_201117630 Show fit	27.62	ENSRNOT00000077908	Tacc2 NCBI RGD Ensembl Show fit	transforming, acidic coiled-coil containing protein 2
chr2_+_119139717 Show fit	27.42	ENSRNOT00000016051	Ndufb5 NCBI RGD Ensembl Show fit	NADH:ubiquinone oxidoreductase subunit B5
chr4_-_145948996 Show fit	27.33	ENSRNOT00000043476	Atp2b2 NCBI RGD Ensembl Show fit	ATPase plasma membrane Ca2+ transporting 2
chr1_+_137799185 Show fit	27.32	ENSRNOT00000083590 ENSRNOT00000092778	Agbl1 NCBI RGD Ensembl Show fit	ATP/GTP binding protein-like 1
chr7_-_74735650 Show fit	27.18	ENSRNOT00000014407	Cox6c NCBI RGD Ensembl Show fit	cytochrome c oxidase subunit 6C
chr1_-_49844547 Show fit	27.16	ENSRNOT00000086127 ENSRNOT00000077423 ENSRNOT00000089439 ENSRNOT00000090521	AABR07001519.1 NCBI RGD Ensembl Show fit
chr9_+_82741920 Show fit	27.11	ENSRNOT00000027337	Slc4a3 NCBI RGD Ensembl Show fit	solute carrier family 4 member 3
chr10_-_15928169 Show fit	27.06	ENSRNOT00000028069	Nsg2 NCBI RGD Ensembl Show fit	neuron specific gene family member 2
chr9_-_69953182 Show fit	27.00	ENSRNOT00000015852	Ndufs1 NCBI RGD Ensembl Show fit	NADH dehydrogenase (ubiquinone) Fe-S protein 1
chr3_+_55910177 Show fit	26.93	ENSRNOT00000009969	Klhl41 NCBI RGD Ensembl Show fit	kelch-like family member 41
chr1_-_219144610 Show fit	26.58	ENSRNOT00000023526	Ndufs8 NCBI RGD Ensembl Show fit	NADH:ubiquinone oxidoreductase core subunit S8
chr1_+_197659187 Show fit	26.30	ENSRNOT00000082228	LOC103690016 NCBI RGD Ensembl Show fit	serine/threonine-protein kinase SBK1
chr7_+_123102493 Show fit	26.09	ENSRNOT00000038612	Aco2 NCBI RGD Ensembl Show fit	aconitase 2
chr11_+_80736576 Show fit	26.05	ENSRNOT00000047678	Masp1 NCBI RGD Ensembl Show fit	mannan-binding lectin serine peptidase 1
chr8_+_116094851 Show fit	26.04	ENSRNOT00000084120	RGD1307461 NCBI RGD Ensembl Show fit	similar to RIKEN cDNA 6430571L13 gene; similar to g20 protein
chr1_-_88066101 Show fit	25.94	ENSRNOT00000079473 ENSRNOT00000027893	Ryr1 NCBI RGD Ensembl Show fit	ryanodine receptor 1
chr8_-_55087832 Show fit	25.85	ENSRNOT00000032152	Dlat NCBI RGD Ensembl Show fit	dihydrolipoamide S-acetyltransferase
chrX_+_53053609 Show fit	25.76	ENSRNOT00000058357	Dmd NCBI RGD Ensembl Show fit	dystrophin
chr9_+_65478496 Show fit	25.50	ENSRNOT00000016060	Ndufb3 NCBI RGD Ensembl Show fit	NADH:ubiquinone oxidoreductase subunit B3
chr8_+_59164572 Show fit	25.43	ENSRNOT00000015102	Idh3a NCBI RGD Ensembl Show fit	isocitrate dehydrogenase 3 (NAD+) alpha
chrX_+_71342775 Show fit	25.39	ENSRNOT00000004888	Itgb1bp2 NCBI RGD Ensembl Show fit	integrin subunit beta 1 binding protein 2
chr17_-_63994169 Show fit	24.91	ENSRNOT00000075651	Chrm3 NCBI RGD Ensembl Show fit	cholinergic receptor, muscarinic 3
chr16_+_23553647 Show fit	24.75	ENSRNOT00000041994	Psd3 NCBI RGD Ensembl Show fit	pleckstrin and Sec7 domain containing 3
chr4_-_80333326 Show fit	24.64	ENSRNOT00000014058	LOC100363502 NCBI RGD Ensembl Show fit	cytochrome c, somatic-like
chrX_+_77263359 Show fit	24.60	ENSRNOT00000077604	Pgk1 NCBI RGD Ensembl Show fit	phosphoglycerate kinase 1
chr10_+_37724915 Show fit	24.34	ENSRNOT00000008477	Vdac1 NCBI RGD Ensembl Show fit	voltage-dependent anion channel 1
chr19_-_37427989 Show fit	24.16	ENSRNOT00000022863	Tppp3 NCBI RGD Ensembl Show fit	tubulin polymerization-promoting protein family member 3
chr20_+_31102476 Show fit	24.06	ENSRNOT00000078719	Lrrc20 NCBI RGD Ensembl Show fit	leucine rich repeat containing 20
chr18_-_56331991 Show fit	23.74	ENSRNOT00000085841 ENSRNOT00000091220	Slc6a7 NCBI RGD Ensembl Show fit	solute carrier family 6 member 7
chr5_+_140870140 Show fit	23.46	ENSRNOT00000074347	Hpcal4 NCBI RGD Ensembl Show fit	hippocalcin-like 4
chr13_-_82758004 Show fit	23.36	ENSRNOT00000003932	Atp1b1 NCBI RGD Ensembl Show fit	ATPase Na+/K+ transporting subunit beta 1
chr3_-_60813869 Show fit	23.36	ENSRNOT00000058234	Atp5g3 NCBI RGD Ensembl Show fit	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)
chr3_+_48096954 Show fit	23.22	ENSRNOT00000068238 ENSRNOT00000064344 ENSRNOT00000044638	Slc4a10 NCBI RGD Ensembl Show fit	solute carrier family 4 member 10
chr7_+_117409576 Show fit	23.03	ENSRNOT00000017067	Cyc1 NCBI RGD Ensembl Show fit	cytochrome c-1
chr2_-_208420163 Show fit	22.95	ENSRNOT00000021920	LOC100911417 NCBI RGD Ensembl Show fit	ATP synthase subunit b, mitochondrial-like
chr4_+_51614676 Show fit	22.87	ENSRNOT00000060494	Asb15 NCBI RGD Ensembl Show fit	ankyrin repeat and SOCS box containing 15
chr5_+_164808323 Show fit	22.56	ENSRNOT00000011005	Nppa NCBI RGD Ensembl Show fit	natriuretic peptide A
chr4_+_49941304 Show fit	22.43	ENSRNOT00000008719	Ptprz1 NCBI RGD Ensembl Show fit	protein tyrosine phosphatase, receptor type Z1
chr8_+_59900651 Show fit	22.37	ENSRNOT00000020410	Tmem266 NCBI RGD Ensembl Show fit	transmembrane protein 266
chr2_+_210977938 Show fit	22.35	ENSRNOT00000074725	Amigo1 NCBI RGD Ensembl Show fit	adhesion molecule with Ig like domain 1
chr7_+_35125424 Show fit	21.82	ENSRNOT00000085978 ENSRNOT00000010117	Ndufa12 NCBI RGD Ensembl Show fit	NADH:ubiquinone oxidoreductase subunit A12
chr10_-_14056169 Show fit	21.56	ENSRNOT00000017833	Syngr3 NCBI RGD Ensembl Show fit	synaptogyrin 3
chr10_-_90995982 Show fit	21.45	ENSRNOT00000093266	Gfap NCBI RGD Ensembl Show fit	glial fibrillary acidic protein
chr1_-_222178725 Show fit	21.45	ENSRNOT00000028697	Esrra NCBI RGD Ensembl Show fit	estrogen related receptor, alpha
chr10_-_83898527 Show fit	21.41	ENSRNOT00000009815	Atp5g1 NCBI RGD Ensembl Show fit	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chrM_-_14061 Show fit	21.28	ENSRNOT00000051268	Mt-nd6 NCBI RGD Ensembl Show fit	mitochondrially encoded NADH dehydrogenase 6
chr13_+_51034256 Show fit	21.14	ENSRNOT00000004528 ENSRNOT00000046854 ENSRNOT00000087320	Mybph NCBI RGD Ensembl Show fit	myosin binding protein H
chr3_-_92969050 Show fit	21.11	ENSRNOT00000088242	Pdhx NCBI RGD Ensembl Show fit	pyruvate dehydrogenase complex, component X
chr10_-_56624526 Show fit	21.05	ENSRNOT00000024973	Acadvl NCBI RGD Ensembl Show fit	acyl-CoA dehydrogenase, very long chain
chr4_+_35279063 Show fit	20.99	ENSRNOT00000011833	Nxph1 NCBI RGD Ensembl Show fit	neurexophilin 1
chr14_+_2325308 Show fit	20.81	ENSRNOT00000000072	Atp5i NCBI RGD Ensembl Show fit	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit E
chr10_+_109658032 Show fit	20.70	ENSRNOT00000054965	Mrpl12 NCBI RGD Ensembl Show fit	mitochondrial ribosomal protein L12
chr5_+_159484370 Show fit	20.59	ENSRNOT00000010593	Sdhb NCBI RGD Ensembl Show fit	succinate dehydrogenase complex iron sulfur subunit B
chr16_+_3293599 Show fit	20.56	ENSRNOT00000081999 ENSRNOT00000047118 ENSRNOT00000020427	Erc2 NCBI RGD Ensembl Show fit	ELKS/RAB6-interacting/CAST family member 2
chr15_-_4026637 Show fit	20.43	ENSRNOT00000012372	Chchd1 NCBI RGD Ensembl Show fit	coiled-coil-helix-coiled-coil-helix domain containing 1
chr3_+_58164931 Show fit	20.17	ENSRNOT00000002078	Dlx1 NCBI RGD Ensembl Show fit	distal-less homeobox 1
chr1_+_268189277 Show fit	20.13	ENSRNOT00000065001	Sorcs3 NCBI RGD Ensembl Show fit	sortilin-related VPS10 domain containing receptor 3
chr8_-_23099042 Show fit	20.02	ENSRNOT00000019115	Ecsit NCBI RGD Ensembl Show fit	ECSIT signalling integrator
chr12_-_44520341 Show fit	19.88	ENSRNOT00000066810	Nos1 NCBI RGD Ensembl Show fit	nitric oxide synthase 1
chr7_-_121029754 Show fit	19.86	ENSRNOT00000004703	Nptxr NCBI RGD Ensembl Show fit	neuronal pentraxin receptor
chr11_-_71757801 Show fit	19.63	ENSRNOT00000029572	Smco1 NCBI RGD Ensembl Show fit	single-pass membrane protein with coiled-coil domains 1
chr5_-_134927235 Show fit	19.62	ENSRNOT00000016751	Uqcrh NCBI RGD Ensembl Show fit	ubiquinol-cytochrome c reductase hinge protein
chr3_+_177226417 Show fit	19.48	ENSRNOT00000031328	Oprl1 NCBI RGD Ensembl Show fit	opioid related nociceptin receptor 1
chrM_+_14136 Show fit	19.42	ENSRNOT00000042098	Mt-cyb NCBI RGD Ensembl Show fit	mitochondrially encoded cytochrome b
chr10_+_11146359 Show fit	19.39	ENSRNOT00000006314	Pam16 NCBI RGD Ensembl Show fit	presequence translocase associated motor 16 homolog
chr8_+_55037750 Show fit	19.39	ENSRNOT00000013188	Timm8b NCBI RGD Ensembl Show fit	translocase of inner mitochondrial membrane 8 homolog B
chr10_-_62698541 Show fit	19.26	ENSRNOT00000019759	Coro6 NCBI RGD Ensembl Show fit	coronin 6
chr2_-_14701903 Show fit	19.25	ENSRNOT00000051895	Cox7c NCBI RGD Ensembl Show fit	cytochrome c oxidase subunit 7C
chr20_-_4489281 Show fit	19.24	ENSRNOT00000031548	Cyp21a1 NCBI RGD Ensembl Show fit	cytochrome P450, family 21, subfamily a, polypeptide 1
chr13_-_85622314 Show fit	19.15	ENSRNOT00000005719	Mgst3 NCBI RGD Ensembl Show fit	microsomal glutathione S-transferase 3
chr2_+_66940057 Show fit	19.12	ENSRNOT00000043050	Cdh9 NCBI RGD Ensembl Show fit	cadherin 9
chr5_-_138545404 Show fit	19.11	ENSRNOT00000011586	Rimkla NCBI RGD Ensembl Show fit	ribosomal modification protein rimK-like family member A
chr1_+_31264755 Show fit	18.86	ENSRNOT00000028988	LOC679739 NCBI RGD Ensembl Show fit	NADH dehydrogenase (ubiquinone) Fe-S protein 6
chr1_+_222519615 Show fit	18.77	ENSRNOT00000083585	Rcor2 NCBI RGD Ensembl Show fit	REST corepressor 2
chr5_+_74766636 Show fit	18.73	ENSRNOT00000030913	Rn50_5_0791.1 NCBI RGD Ensembl Show fit
chr6_+_83083740 Show fit	18.65	ENSRNOT00000007600	Lrfn5 NCBI RGD Ensembl Show fit	leucine rich repeat and fibronectin type III domain containing 5
chr12_+_42097626 Show fit	18.45	ENSRNOT00000001893	Tbx5 NCBI RGD Ensembl Show fit	T-box 5
chr2_-_178389608 Show fit	18.29	ENSRNOT00000013262	Etfdh NCBI RGD Ensembl Show fit	electron transfer flavoprotein dehydrogenase
chr10_+_82775691 Show fit	18.27	ENSRNOT00000030737	Hils1 NCBI RGD Ensembl Show fit	histone linker H1 domain, spermatid-specific 1
chr1_-_80630038 Show fit	18.21	ENSRNOT00000025281	Tomm40 NCBI RGD Ensembl Show fit	translocase of outer mitochondrial membrane 40
chr4_+_113968995 Show fit	17.91	ENSRNOT00000079511	Rtkn NCBI RGD Ensembl Show fit	rhotekin
chr2_-_119140110 Show fit	17.89	ENSRNOT00000058810	AABR07009978.1 NCBI RGD Ensembl Show fit
chr3_+_131351587 Show fit	17.76	ENSRNOT00000010835	Btbd3 NCBI RGD Ensembl Show fit	BTB domain containing 3
chr4_+_49369296 Show fit	17.69	ENSRNOT00000007822	Wnt16 NCBI RGD Ensembl Show fit	wingless-type MMTV integration site family, member 16
chr18_-_29587760 Show fit	17.66	ENSRNOT00000023811	Ndufa2 NCBI RGD Ensembl Show fit	NADH:ubiquinone oxidoreductase subunit A2
chr5_-_130085838 Show fit	17.66	ENSRNOT00000035252	Elavl4 NCBI RGD Ensembl Show fit	ELAV like RNA binding protein 4
chr10_-_50574539 Show fit	17.51	ENSRNOT00000034261	Cox10 NCBI RGD Ensembl Show fit	COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor
chr4_-_55407922 Show fit	17.40	ENSRNOT00000031714	Grm8 NCBI RGD Ensembl Show fit	glutamate metabotropic receptor 8
chr15_-_93307420 Show fit	17.31	ENSRNOT00000012195	Slitrk1 NCBI RGD Ensembl Show fit	SLIT and NTRK-like family, member 1
chr1_+_215609036 Show fit	17.30	ENSRNOT00000076187	Tnni2 NCBI RGD Ensembl Show fit	troponin I2, fast skeletal type
chr8_+_29453643 Show fit	17.16	ENSRNOT00000090643	Opcml NCBI RGD Ensembl Show fit	opioid binding protein/cell adhesion molecule-like
chr8_+_117679278 Show fit	17.07	ENSRNOT00000042114	Uqcrc1 NCBI RGD Ensembl Show fit	ubiquinol-cytochrome c reductase core protein I
chr8_-_130491998 Show fit	17.06	ENSRNOT00000064114	Higd1a NCBI RGD Ensembl Show fit	HIG1 hypoxia inducible domain family, member 1A
chrX_+_53360839 Show fit	17.00	ENSRNOT00000091467 ENSRNOT00000034372 ENSRNOT00000081061	Dmd NCBI RGD Ensembl Show fit	dystrophin
chr6_+_109110534 Show fit	16.90	ENSRNOT00000009156	Zc2hc1c NCBI RGD Ensembl Show fit	zinc finger, C2HC-type containing 1C
chr4_+_138269142 Show fit	16.82	ENSRNOT00000007788	Cntn4 NCBI RGD Ensembl Show fit	contactin 4
chr20_+_5815837 Show fit	16.80	ENSRNOT00000036999	Lhfpl5 NCBI RGD Ensembl Show fit	lipoma HMGIC fusion partner-like 5
chr2_-_140464607 Show fit	16.37	ENSRNOT00000058190	Ndufc1 NCBI RGD Ensembl Show fit	NADH:ubiquinone oxidoreductase subunit C1
chrX_+_37579957 Show fit	16.26	ENSRNOT00000008509	Eif1ax NCBI RGD Ensembl Show fit	eukaryotic translation initiation factor 1A, X-linked
chr5_-_58163584 Show fit	16.22	ENSRNOT00000060594	Ccl27 NCBI RGD Ensembl Show fit	C-C motif chemokine ligand 27
chr1_-_64175099 Show fit	16.19	ENSRNOT00000091288	Ndufa3 NCBI RGD Ensembl Show fit	NADH:ubiquinone oxidoreductase subunit A3
chr4_-_157381105 Show fit	15.95	ENSRNOT00000021670	Gpr162 NCBI RGD Ensembl Show fit	G protein-coupled receptor 162
chr14_-_84937725 Show fit	15.80	ENSRNOT00000083839	Uqcr10 NCBI RGD Ensembl Show fit	ubiquinol-cytochrome c reductase, complex III subunit X
chr19_-_10596851 Show fit	15.72	ENSRNOT00000021716	Coq9 NCBI RGD Ensembl Show fit	coenzyme Q9
chr17_+_13670520 Show fit	15.71	ENSRNOT00000019442	Shc3 NCBI RGD Ensembl Show fit	SHC adaptor protein 3
chr1_+_255186728 Show fit	15.63	ENSRNOT00000086991	Hectd2 NCBI RGD Ensembl Show fit	HECT domain E3 ubiquitin protein ligase 2
chr13_-_93677377 Show fit	15.59	ENSRNOT00000004917	Fh NCBI RGD Ensembl Show fit	fumarate hydratase
chrM_+_3904 Show fit	15.59	ENSRNOT00000040993	Mt-nd2 NCBI RGD Ensembl Show fit	mitochondrially encoded NADH dehydrogenase 2
chr1_+_220335254 Show fit	15.50	ENSRNOT00000072261	Rin1 NCBI RGD Ensembl Show fit	Ras and Rab interactor 1
chr18_-_55891710 Show fit	15.49	ENSRNOT00000064686	Synpo NCBI RGD Ensembl Show fit	synaptopodin
chr19_-_37440471 Show fit	15.45	ENSRNOT00000066636	Zdhhc1 NCBI RGD Ensembl Show fit	zinc finger, DHHC-type containing 1
chr17_+_12310214 Show fit	15.29	ENSRNOT00000015786	Auh NCBI RGD Ensembl Show fit	AU RNA binding methylglutaconyl-CoA hydratase
chr9_+_82571269 Show fit	15.26	ENSRNOT00000026941	Speg NCBI RGD Ensembl Show fit	SPEG complex locus
chr1_-_183763664 Show fit	15.25	ENSRNOT00000044231	LOC691427 NCBI RGD Ensembl Show fit	similar to 6.8 kDa mitochondrial proteolipid
chr6_+_106496992 Show fit	15.08	ENSRNOT00000086136 ENSRNOT00000058181	Rgs6 NCBI RGD Ensembl Show fit	regulator of G-protein signaling 6
chr10_-_56403188 Show fit	15.05	ENSRNOT00000019947	Chrnb1 NCBI RGD Ensembl Show fit	cholinergic receptor nicotinic beta 1 subunit
chr19_+_54245950 Show fit	15.01	ENSRNOT00000024033	Cox4i1 NCBI RGD Ensembl Show fit	cytochrome c oxidase subunit 4i1
chr7_-_117267803 Show fit	14.82	ENSRNOT00000082271	Plec NCBI RGD Ensembl Show fit	plectin
chr2_+_209840404 Show fit	14.56	ENSRNOT00000050149	Kcna2 NCBI RGD Ensembl Show fit	potassium voltage-gated channel subfamily A member 2
chr2_+_95045034 Show fit	14.56	ENSRNOT00000081305	Mrps28 NCBI RGD Ensembl Show fit	mitochondrial ribosomal protein S28
chr18_+_15467870 Show fit	14.49	ENSRNOT00000091696	B4galt6 NCBI RGD Ensembl Show fit	beta-1,4-galactosyltransferase 6
chr1_-_16203838 Show fit	14.41	ENSRNOT00000018556 ENSRNOT00000078586	Pde7b NCBI RGD Ensembl Show fit	phosphodiesterase 7B
chr7_+_141326950 Show fit	14.37	ENSRNOT00000084075	Asic1 NCBI RGD Ensembl Show fit	acid sensing ion channel subunit 1
chr1_+_101687855 Show fit	14.35	ENSRNOT00000028546 ENSRNOT00000091597	Dbp NCBI RGD Ensembl Show fit	D-box binding PAR bZIP transcription factor
chr10_+_56381813 Show fit	14.34	ENSRNOT00000019687	Zbtb4 NCBI RGD Ensembl Show fit	zinc finger and BTB domain containing 4
chr1_+_220428481 Show fit	14.29	ENSRNOT00000027335	LOC108348044 NCBI RGD Ensembl Show fit	ras and Rab interactor 1
chr1_+_97632473 Show fit	14.29	ENSRNOT00000023671	Vstm2b NCBI RGD Ensembl Show fit	V-set and transmembrane domain containing 2B
chr1_-_64350338 Show fit	14.12	ENSRNOT00000078444	Cacng8 NCBI RGD Ensembl Show fit	calcium voltage-gated channel auxiliary subunit gamma 8
chr10_+_85257876 Show fit	14.08	ENSRNOT00000014752	Mrpl45 NCBI RGD Ensembl Show fit	mitochondrial ribosomal protein L45
chr3_-_81304181 Show fit	14.00	ENSRNOT00000079746	Mapk8ip1 NCBI RGD Ensembl Show fit	mitogen-activated protein kinase 8 interacting protein 1
chr16_+_23668595 Show fit	13.94	ENSRNOT00000067886	Psd3 NCBI RGD Ensembl Show fit	pleckstrin and Sec7 domain containing 3
chr6_-_136550371 Show fit	13.93	ENSRNOT00000065971	Rd3l NCBI RGD Ensembl Show fit	retinal degeneration 3-like
chr1_+_101884276 Show fit	13.80	ENSRNOT00000082917	Tmem143 NCBI RGD Ensembl Show fit	transmembrane protein 143
chr1_-_222350173 Show fit	13.76	ENSRNOT00000030625	Flrt1 NCBI RGD Ensembl Show fit	fibronectin leucine rich transmembrane protein 1
chr1_-_88826302 Show fit	13.34	ENSRNOT00000028275	Lrfn3 NCBI RGD Ensembl Show fit	leucine rich repeat and fibronectin type III domain containing 3
chr15_+_61662264 Show fit	13.15	ENSRNOT00000072969	Mtrf1 NCBI RGD Ensembl Show fit	mitochondrial translation release factor 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Ppara

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
35.5	106.6	GO:2001137	actin filament uncapping(GO:0051695) phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097) positive regulation of endocytic recycling(GO:2001137)
24.2	96.6	GO:0014873	response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
19.5	97.5	GO:0007197	adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
18.5	74.1	GO:0030240	skeletal muscle thin filament assembly(GO:0030240)
17.4	34.7	GO:1904457	positive regulation of neuronal action potential(GO:1904457)
15.5	46.5	GO:0006106	fumarate metabolic process(GO:0006106)
14.4	86.3	GO:1903059	regulation of protein lipidation(GO:1903059)
14.3	42.8	GO:0021629	muscle attachment(GO:0016203) olfactory nerve morphogenesis(GO:0021627) olfactory nerve structural organization(GO:0021629)
13.1	65.3	GO:1903278	positive regulation of sodium ion export(GO:1903275) positive regulation of sodium ion export from cell(GO:1903278)
12.3	36.9	GO:0010747	positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747)
11.9	35.7	GO:0045763	negative regulation of cellular amino acid metabolic process(GO:0045763)
11.0	33.0	GO:0021539	subthalamus development(GO:0021539)
10.7	32.0	GO:0032417	positive regulation of sodium:proton antiporter activity(GO:0032417)
9.9	19.9	GO:1901204	regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901204)
9.8	39.1	GO:1904428	negative regulation of tubulin deacetylation(GO:1904428)
9.6	28.7	GO:1901079	positive regulation of relaxation of muscle(GO:1901079)
8.8	35.1	GO:0042776	mitochondrial ATP synthesis coupled proton transport(GO:0042776)
8.6	51.5	GO:0006102	isocitrate metabolic process(GO:0006102)
8.2	90.4	GO:0006108	malate metabolic process(GO:0006108)
7.5	22.6	GO:1902304	positive regulation of potassium ion export(GO:1902304)
7.3	80.7	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
7.0	35.0	GO:0036376	sodium ion export from cell(GO:0036376)
6.9	34.4	GO:0019563	glycerol catabolic process(GO:0019563)
6.7	20.2	GO:0021882	regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898)
6.3	19.0	GO:0006121	mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
6.3	43.9	GO:0060316	positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
6.2	12.4	GO:0003350	pulmonary myocardium development(GO:0003350)
5.6	22.4	GO:0036135	Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
5.4	10.9	GO:0099543	retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543)
5.4	32.4	GO:1904714	positive regulation of Schwann cell proliferation(GO:0010625) regulation of chaperone-mediated autophagy(GO:1904714)
5.0	130.9	GO:0010614	negative regulation of cardiac muscle hypertrophy(GO:0010614)
5.0	123.9	GO:0015985	energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
4.9	39.3	GO:1903546	protein localization to photoreceptor outer segment(GO:1903546)
4.9	39.1	GO:0055096	lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)
4.9	9.7	GO:1903070	negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
4.6	27.3	GO:0035609	C-terminal protein deglutamylation(GO:0035609)
4.4	8.8	GO:0043134	hindgut contraction(GO:0043133) regulation of hindgut contraction(GO:0043134)
4.4	13.1	GO:2000546	positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
4.3	25.9	GO:0071313	cellular response to caffeine(GO:0071313)
4.2	58.9	GO:0071420	cellular response to histamine(GO:0071420)
4.2	12.5	GO:0021740	trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740)
4.1	16.6	GO:1904059	regulation of locomotor rhythm(GO:1904059)
4.1	12.4	GO:2001160	regulation of histone H3-K79 methylation(GO:2001160)
4.1	44.9	GO:0007196	adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
4.1	12.2	GO:1904937	pancreatic A cell development(GO:0003322) forebrain-midbrain boundary formation(GO:0021905) somatic motor neuron fate commitment(GO:0021917) regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment(GO:0021918) sensory neuron migration(GO:1904937)
3.9	31.4	GO:0019388	galactose catabolic process(GO:0019388)
3.9	11.7	GO:0071691	cardiac muscle thin filament assembly(GO:0071691)
3.9	15.5	GO:0098886	modification of dendritic spine(GO:0098886)
3.7	18.4	GO:0003166	bundle of His development(GO:0003166)
3.7	88.3	GO:2001014	regulation of skeletal muscle cell differentiation(GO:2001014)
3.6	39.3	GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
3.5	10.4	GO:0015864	pyrimidine nucleoside transport(GO:0015864)
3.4	27.3	GO:0048840	otolith development(GO:0048840)
3.4	47.0	GO:0006086	acetyl-CoA biosynthetic process from pyruvate(GO:0006086)
3.3	62.6	GO:0045475	locomotor rhythm(GO:0045475)
3.2	9.5	GO:0030091	protein repair(GO:0030091)
3.1	30.7	GO:0007220	Notch receptor processing(GO:0007220)
3.0	29.8	GO:0014883	transition between fast and slow fiber(GO:0014883)
2.9	17.4	GO:0021633	optic nerve structural organization(GO:0021633)
2.8	47.7	GO:0042761	very long-chain fatty acid biosynthetic process(GO:0042761)
2.8	44.7	GO:0051386	regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
2.7	16.2	GO:0071677	positive regulation of mononuclear cell migration(GO:0071677)
2.7	43.2	GO:0030150	protein import into mitochondrial matrix(GO:0030150)
2.7	10.7	GO:0010615	positive regulation of cardiac muscle adaptation(GO:0010615) regulation of cardiac muscle hypertrophy in response to stress(GO:1903242) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
2.6	31.6	GO:0010882	regulation of cardiac muscle contraction by calcium ion signaling(GO:0010882)
2.5	7.6	GO:0060086	circadian temperature homeostasis(GO:0060086)
2.5	12.3	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
2.4	159.7	GO:0022900	electron transport chain(GO:0022900)
2.4	23.7	GO:0035524	proline transmembrane transport(GO:0035524)
2.4	77.7	GO:0035025	positive regulation of Rho protein signal transduction(GO:0035025)
2.3	21.1	GO:0071688	striated muscle myosin thick filament assembly(GO:0071688)
2.2	15.5	GO:0031914	negative regulation of synaptic plasticity(GO:0031914)
2.2	6.6	GO:0009644	response to high light intensity(GO:0009644)
2.2	30.7	GO:1904322	response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
2.2	11.0	GO:0015793	glycerol transport(GO:0015793)
2.2	10.9	GO:0044861	protein transport into plasma membrane raft(GO:0044861)
2.1	27.6	GO:0022027	interkinetic nuclear migration(GO:0022027)
2.1	14.4	GO:0050915	sensory perception of sour taste(GO:0050915)
2.0	5.9	GO:1903542	negative regulation of exosomal secretion(GO:1903542)
2.0	11.8	GO:0032914	positive regulation of transforming growth factor beta1 production(GO:0032914)
1.9	26.9	GO:0006851	mitochondrial calcium ion transport(GO:0006851)
1.9	11.4	GO:0086047	regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373) membrane depolarization during Purkinje myocyte cell action potential(GO:0086047) membrane depolarization during bundle of His cell action potential(GO:0086048) membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912)
1.8	5.5	GO:0090164	asymmetric Golgi ribbon formation(GO:0090164)
1.8	9.1	GO:0051596	methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
1.8	27.3	GO:0035970	peptidyl-threonine dephosphorylation(GO:0035970)
1.8	39.2	GO:0097503	sialylation(GO:0097503)
1.8	8.8	GO:0060478	acrosomal vesicle exocytosis(GO:0060478)
1.7	14.0	GO:0007258	JUN phosphorylation(GO:0007258)
1.7	5.2	GO:0014826	vein smooth muscle contraction(GO:0014826)
1.7	15.3	GO:0070601	centromeric sister chromatid cohesion(GO:0070601)
1.7	21.9	GO:0006390	transcription from mitochondrial promoter(GO:0006390)
1.7	10.1	GO:0090403	oxidative stress-induced premature senescence(GO:0090403)
1.7	10.0	GO:0015074	DNA integration(GO:0015074)
1.6	11.3	GO:0000160	phosphorelay signal transduction system(GO:0000160)
1.6	38.2	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
1.6	31.8	GO:0014850	response to muscle activity(GO:0014850)
1.5	12.1	GO:0060385	axonogenesis involved in innervation(GO:0060385)
1.5	4.5	GO:0033552	response to vitamin B3(GO:0033552)
1.5	6.0	GO:0070940	dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
1.5	28.3	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
1.5	19.2	GO:0042448	progesterone metabolic process(GO:0042448)
1.5	7.4	GO:0001579	medium-chain fatty acid transport(GO:0001579)
1.5	2.9	GO:0072076	nephrogenic mesenchyme development(GO:0072076)
1.5	11.7	GO:1901897	regulation of relaxation of cardiac muscle(GO:1901897)
1.5	11.6	GO:2000346	negative regulation of hepatocyte proliferation(GO:2000346)
1.4	2.9	GO:1903286	regulation of potassium ion import(GO:1903286)
1.4	5.7	GO:1901906	diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
1.4	27.0	GO:0031581	hemidesmosome assembly(GO:0031581)
1.4	28.4	GO:0019682	pentose-phosphate shunt(GO:0006098) glyceraldehyde-3-phosphate metabolic process(GO:0019682)
1.4	7.1	GO:0000957	mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
1.4	37.8	GO:0046856	phosphatidylinositol dephosphorylation(GO:0046856)
1.4	41.7	GO:0045214	sarcomere organization(GO:0045214)
1.4	5.5	GO:0019042	viral latency(GO:0019042) release from viral latency(GO:0019046)
1.4	16.4	GO:0045916	negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
1.4	9.5	GO:0043951	negative regulation of cAMP-mediated signaling(GO:0043951)
1.4	12.2	GO:0035879	plasma membrane lactate transport(GO:0035879)
1.3	14.5	GO:0006688	glycosphingolipid biosynthetic process(GO:0006688)
1.3	16.8	GO:0060088	auditory receptor cell stereocilium organization(GO:0060088)
1.3	23.2	GO:0021860	pyramidal neuron development(GO:0021860)
1.3	7.5	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
1.2	11.1	GO:0070345	negative regulation of fat cell proliferation(GO:0070345)
1.2	10.9	GO:0006527	arginine catabolic process(GO:0006527)
1.2	17.5	GO:0008535	respiratory chain complex IV assembly(GO:0008535)
1.2	15.1	GO:0035095	behavioral response to nicotine(GO:0035095)
1.2	6.9	GO:0060723	regulation of spongiotrophoblast cell proliferation(GO:0060721) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
1.1	11.5	GO:1901642	nucleoside transmembrane transport(GO:1901642)
1.1	17.1	GO:0010257	NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
1.1	4.5	GO:0090074	negative regulation of protein homodimerization activity(GO:0090074)
1.1	12.3	GO:0000338	protein deneddylation(GO:0000338)
1.1	2.2	GO:0032510	endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
1.1	32.5	GO:0007413	axonal fasciculation(GO:0007413)
1.1	40.9	GO:0007340	acrosome reaction(GO:0007340)
1.1	10.6	GO:1902993	positive regulation of beta-amyloid formation(GO:1902004) positive regulation of amyloid precursor protein catabolic process(GO:1902993)
1.0	20.1	GO:1900452	regulation of long term synaptic depression(GO:1900452)
1.0	1.0	GO:0072709	cellular response to sorbitol(GO:0072709)
1.0	3.0	GO:2000015	regulation of determination of dorsal identity(GO:2000015)
1.0	3.0	GO:0010796	regulation of multivesicular body size(GO:0010796)
1.0	3.9	GO:0060315	negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
1.0	2.9	GO:0008594	photoreceptor cell morphogenesis(GO:0008594) post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
0.9	11.4	GO:0007614	short-term memory(GO:0007614)
0.9	2.8	GO:1902037	negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.9	5.6	GO:2000973	regulation of pro-B cell differentiation(GO:2000973)
0.9	11.9	GO:0043374	CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.9	8.2	GO:0030644	cellular chloride ion homeostasis(GO:0030644)
0.9	35.6	GO:0007026	negative regulation of microtubule depolymerization(GO:0007026)
0.9	1.7	GO:0061055	myotome development(GO:0061055)
0.8	3.3	GO:0019464	glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.8	3.3	GO:0060529	ectoderm and mesoderm interaction(GO:0007499) squamous basal epithelial stem cell differentiation involved in prostate gland acinus development(GO:0060529)
0.8	9.8	GO:0034643	establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.8	5.3	GO:0033634	positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.7	8.9	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.7	2.9	GO:0032747	positive regulation of interleukin-23 production(GO:0032747)
0.7	11.0	GO:1902259	regulation of delayed rectifier potassium channel activity(GO:1902259)
0.7	26.1	GO:0046825	regulation of protein export from nucleus(GO:0046825)
0.7	10.1	GO:0007097	nuclear migration(GO:0007097)
0.7	7.2	GO:0002860	positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.7	14.1	GO:2000311	regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.7	7.7	GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.7	2.8	GO:1901491	negative regulation of lymphangiogenesis(GO:1901491)
0.7	2.1	GO:1903544	response to butyrate(GO:1903544)
0.7	9.5	GO:0099612	protein localization to axon(GO:0099612)
0.7	5.4	GO:1903301	positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.7	2.0	GO:2000324	positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.6	9.6	GO:0001675	acrosome assembly(GO:0001675) sperm axoneme assembly(GO:0007288)
0.6	34.5	GO:0045739	positive regulation of DNA repair(GO:0045739)
0.6	3.8	GO:0070836	caveola assembly(GO:0070836)
0.6	6.2	GO:0097499	protein localization to nonmotile primary cilium(GO:0097499)
0.6	3.6	GO:0097039	protein linear polyubiquitination(GO:0097039)
0.6	6.7	GO:0051560	mitochondrial calcium ion homeostasis(GO:0051560)
0.5	31.1	GO:0051965	positive regulation of synapse assembly(GO:0051965)
0.5	2.1	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.5	7.4	GO:0031340	positive regulation of vesicle fusion(GO:0031340)
0.5	8.7	GO:0016558	protein import into peroxisome matrix(GO:0016558)
0.5	8.1	GO:0000042	protein targeting to Golgi(GO:0000042)
0.5	3.5	GO:0044351	macropinocytosis(GO:0044351)
0.5	21.6	GO:0021762	substantia nigra development(GO:0021762)
0.5	2.9	GO:0034393	positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.5	10.1	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.5	29.3	GO:0042220	response to cocaine(GO:0042220)
0.5	19.0	GO:0042149	cellular response to glucose starvation(GO:0042149)
0.5	49.9	GO:0006941	striated muscle contraction(GO:0006941)
0.5	2.3	GO:2000327	regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
0.5	12.7	GO:0015701	bicarbonate transport(GO:0015701)
0.4	22.8	GO:0035249	synaptic transmission, glutamatergic(GO:0035249)
0.4	19.0	GO:0055013	cardiac muscle cell development(GO:0055013)
0.4	2.1	GO:0014870	response to muscle inactivity(GO:0014870)
0.4	23.8	GO:0006096	glycolytic process(GO:0006096)
0.4	2.1	GO:0042264	peptidyl-aspartic acid hydroxylation(GO:0042264)
0.4	27.3	GO:1902600	hydrogen ion transmembrane transport(GO:1902600)
0.4	3.3	GO:0007182	common-partner SMAD protein phosphorylation(GO:0007182)
0.4	6.1	GO:0090344	positive regulation of mitochondrial fission(GO:0090141) negative regulation of cell aging(GO:0090344)
0.4	13.1	GO:0030261	chromosome condensation(GO:0030261)
0.4	2.0	GO:0045656	negative regulation of monocyte differentiation(GO:0045656)
0.4	10.6	GO:0006611	protein export from nucleus(GO:0006611)
0.4	1.5	GO:0032509	endosome transport via multivesicular body sorting pathway(GO:0032509)
0.4	12.8	GO:0014003	oligodendrocyte development(GO:0014003)
0.4	1.8	GO:1902035	positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.4	3.9	GO:0033141	regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033139) positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141) serine phosphorylation of STAT protein(GO:0042501)
0.4	2.5	GO:0035989	tendon development(GO:0035989)
0.3	10.0	GO:0030728	ovulation(GO:0030728)
0.3	3.0	GO:2000060	positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060)
0.3	38.4	GO:0031032	actomyosin structure organization(GO:0031032)
0.3	3.9	GO:1901409	positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.3	4.5	GO:0051085	chaperone mediated protein folding requiring cofactor(GO:0051085)
0.3	7.5	GO:0034260	negative regulation of GTPase activity(GO:0034260)
0.3	2.8	GO:0043649	dicarboxylic acid catabolic process(GO:0043649)
0.3	20.6	GO:0007416	synapse assembly(GO:0007416)
0.3	7.8	GO:0048488	synaptic vesicle endocytosis(GO:0048488)
0.3	25.4	GO:0007229	integrin-mediated signaling pathway(GO:0007229)
0.3	3.1	GO:0015732	prostaglandin transport(GO:0015732)
0.3	4.8	GO:0006415	translational termination(GO:0006415)
0.3	0.8	GO:0042196	chlorinated hydrocarbon metabolic process(GO:0042196) halogenated hydrocarbon metabolic process(GO:0042197)
0.3	18.8	GO:0010923	negative regulation of phosphatase activity(GO:0010923)
0.2	2.9	GO:0048268	clathrin coat assembly(GO:0048268)
0.2	0.7	GO:1900104	hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.2	10.7	GO:0032543	mitochondrial translation(GO:0032543)
0.2	6.6	GO:0043001	Golgi to plasma membrane protein transport(GO:0043001)
0.2	2.2	GO:0061525	hindgut development(GO:0061525)
0.2	17.2	GO:0021987	cerebral cortex development(GO:0021987)
0.2	4.8	GO:1900078	positive regulation of cellular response to insulin stimulus(GO:1900078)
0.2	2.2	GO:0030238	male sex determination(GO:0030238)
0.2	13.6	GO:0001578	microtubule bundle formation(GO:0001578)
0.2	3.2	GO:2000114	regulation of establishment of cell polarity(GO:2000114)
0.2	5.2	GO:0001662	behavioral fear response(GO:0001662) behavioral defense response(GO:0002209)
0.2	2.6	GO:0099517	anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.2	12.6	GO:1902476	chloride transmembrane transport(GO:1902476)
0.2	8.1	GO:0006635	fatty acid beta-oxidation(GO:0006635)
0.2	6.9	GO:0051290	protein heterotetramerization(GO:0051290)
0.2	5.7	GO:1901998	toxin transport(GO:1901998)
0.1	1.7	GO:0030277	maintenance of gastrointestinal epithelium(GO:0030277)
0.1	6.5	GO:0019933	cAMP-mediated signaling(GO:0019933)
0.1	4.6	GO:0061077	chaperone-mediated protein folding(GO:0061077)
0.1	11.3	GO:0006665	sphingolipid metabolic process(GO:0006665)
0.1	5.9	GO:0000186	activation of MAPKK activity(GO:0000186)
0.1	9.4	GO:0021549	cerebellum development(GO:0021549)
0.1	16.7	GO:0007411	axon guidance(GO:0007411)
0.1	3.5	GO:0032728	positive regulation of interferon-beta production(GO:0032728)
0.1	6.2	GO:0001707	mesoderm formation(GO:0001707)
0.1	2.1	GO:0043968	histone H2A acetylation(GO:0043968)
0.1	1.3	GO:0043982	histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.1	0.7	GO:0006099	tricarboxylic acid cycle(GO:0006099)
0.1	2.1	GO:0010824	regulation of centrosome duplication(GO:0010824) SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.1	2.5	GO:0051693	actin filament capping(GO:0051693)
0.1	2.2	GO:0070534	protein K63-linked ubiquitination(GO:0070534)
0.1	4.6	GO:0007030	Golgi organization(GO:0007030)
0.1	0.3	GO:0033227	dsRNA transport(GO:0033227)
0.0	2.9	GO:0006888	ER to Golgi vesicle-mediated transport(GO:0006888)
0.0	0.2	GO:0006198	cAMP catabolic process(GO:0006198)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
13.2	39.6	GO:0045283	mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) fumarate reductase complex(GO:0045283)
9.3	112.2	GO:0045275	respiratory chain complex III(GO:0045275)
8.8	17.5	GO:0070069	cytochrome complex(GO:0070069)
8.7	35.0	GO:0044326	dendritic spine neck(GO:0044326)
8.5	25.4	GO:0005962	mitochondrial isocitrate dehydrogenase complex (NAD+)(GO:0005962) isocitrate dehydrogenase complex (NAD+)(GO:0045242)
8.1	32.4	GO:0098574	cytoplasmic side of lysosomal membrane(GO:0098574)
7.9	31.6	GO:1990584	cardiac Troponin complex(GO:1990584)
7.8	69.8	GO:0030314	junctional membrane complex(GO:0030314)
7.7	15.5	GO:0097444	spine apparatus(GO:0097444)
7.7	38.4	GO:0005927	muscle tendon junction(GO:0005927)
7.3	29.2	GO:1990761	growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
6.9	34.7	GO:0044316	cone cell pedicle(GO:0044316)
6.3	133.0	GO:0005865	striated muscle thin filament(GO:0005865)
5.4	32.3	GO:0032280	symmetric synapse(GO:0032280)
5.3	69.0	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
5.0	20.0	GO:0001405	presequence translocase-associated import motor(GO:0001405)
4.7	47.0	GO:0045254	pyruvate dehydrogenase complex(GO:0045254)
4.7	14.0	GO:0044302	dentate gyrus mossy fiber(GO:0044302)
4.5	22.4	GO:0072534	perineuronal net(GO:0072534)
4.4	349.7	GO:0070469	respiratory chain(GO:0070469)
4.1	12.3	GO:0048269	methionine adenosyltransferase complex(GO:0048269)
4.0	31.9	GO:0000275	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
3.9	23.2	GO:0097441	basilar dendrite(GO:0097441)
3.5	59.4	GO:0098984	asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
3.1	6.1	GO:0097512	cardiac myofibril(GO:0097512)
3.0	27.3	GO:0098839	postsynaptic density membrane(GO:0098839)
2.9	2.9	GO:0070033	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
2.9	28.7	GO:0042583	chromaffin granule(GO:0042583)
2.6	60.7	GO:1902711	GABA-A receptor complex(GO:1902711)
2.6	20.9	GO:0005753	mitochondrial proton-transporting ATP synthase complex(GO:0005753)
2.6	23.1	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
2.3	42.8	GO:0016010	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
2.1	23.4	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
2.1	6.4	GO:0032173	septin collar(GO:0032173)
2.1	14.6	GO:0031415	NatA complex(GO:0031415)
2.1	26.9	GO:0031143	pseudopodium(GO:0031143)
2.0	19.8	GO:0042788	polysomal ribosome(GO:0042788)
1.9	9.5	GO:1990769	proximal neuron projection(GO:1990769)
1.8	275.6	GO:0030018	Z disc(GO:0030018)
1.5	4.5	GO:0097451	glial limiting end-foot(GO:0097451)
1.5	16.3	GO:0045239	tricarboxylic acid cycle enzyme complex(GO:0045239)
1.4	76.4	GO:0030017	sarcomere(GO:0030017)
1.4	27.0	GO:0043034	costamere(GO:0043034)
1.3	44.3	GO:0034707	chloride channel complex(GO:0034707)
1.2	16.8	GO:0032426	stereocilium tip(GO:0032426)
1.2	32.1	GO:0042629	mast cell granule(GO:0042629)
1.2	110.4	GO:0042734	presynaptic membrane(GO:0042734)
1.2	11.7	GO:0033017	sarcoplasmic reticulum membrane(GO:0033017)
1.1	119.7	GO:0016605	PML body(GO:0016605)
1.1	7.9	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
1.1	3.3	GO:0005960	glycine cleavage complex(GO:0005960)
1.1	10.9	GO:0044354	pinosome(GO:0044352) macropinosome(GO:0044354)
1.1	61.2	GO:0043198	dendritic shaft(GO:0043198)
1.0	5.2	GO:0070552	BRISC complex(GO:0070552)
1.0	3.0	GO:0036488	CHOP-C/EBP complex(GO:0036488) CHOP-ATF3 complex(GO:1990622)
0.9	23.2	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
0.9	25.2	GO:0000314	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.9	42.2	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.9	2.6	GO:0005745	m-AAA complex(GO:0005745)
0.8	56.0	GO:0000313	organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.8	5.9	GO:0071986	Ragulator complex(GO:0071986)
0.8	15.1	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.8	24.8	GO:0032809	neuronal cell body membrane(GO:0032809)
0.8	2.5	GO:0005592	collagen type XI trimer(GO:0005592)
0.8	38.6	GO:0009295	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.8	7.0	GO:0005797	Golgi medial cisterna(GO:0005797)
0.8	64.8	GO:0001750	photoreceptor outer segment(GO:0001750)
0.7	5.2	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.7	10.9	GO:0071565	nBAF complex(GO:0071565)
0.7	3.6	GO:0071797	LUBAC complex(GO:0071797)
0.7	18.3	GO:0031305	intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.7	52.0	GO:0099501	synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.7	2.1	GO:0005943	phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.7	5.9	GO:0000306	extrinsic component of vacuolar membrane(GO:0000306)
0.6	14.1	GO:0032281	AMPA glutamate receptor complex(GO:0032281)
0.6	11.7	GO:0001673	male germ cell nucleus(GO:0001673)
0.5	5.9	GO:0043205	microfibril(GO:0001527) fibril(GO:0043205)
0.5	5.3	GO:0036057	filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.5	7.5	GO:0034709	methylosome(GO:0034709)
0.5	17.0	GO:0008180	COP9 signalosome(GO:0008180)
0.5	7.5	GO:0030061	mitochondrial crista(GO:0030061)
0.5	2.3	GO:0030015	CCR4-NOT core complex(GO:0030015)
0.4	15.1	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.4	5.7	GO:0035253	ciliary rootlet(GO:0035253)
0.4	37.6	GO:0005901	caveola(GO:0005901)
0.4	14.0	GO:0031201	SNARE complex(GO:0031201)
0.4	2.2	GO:0097598	sperm cytoplasmic droplet(GO:0097598)
0.4	38.9	GO:0005759	mitochondrial matrix(GO:0005759)
0.3	20.0	GO:0031903	peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.3	79.2	GO:0005743	mitochondrial inner membrane(GO:0005743)
0.3	1.7	GO:0030991	intraciliary transport particle A(GO:0030991)
0.3	2.2	GO:0000815	ESCRT III complex(GO:0000815)
0.3	34.5	GO:0043679	axon terminus(GO:0043679)
0.3	2.1	GO:0032541	cortical endoplasmic reticulum(GO:0032541)
0.2	0.7	GO:0036117	hyaluranon cable(GO:0036117)
0.2	2.8	GO:0044439	microbody part(GO:0044438) peroxisomal part(GO:0044439)
0.2	7.7	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.2	2.0	GO:1990635	proximal dendrite(GO:1990635)
0.2	2.6	GO:0030123	AP-3 adaptor complex(GO:0030123)
0.2	11.4	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.2	2.9	GO:0030131	clathrin adaptor complex(GO:0030131)
0.2	24.9	GO:0001650	fibrillar center(GO:0001650)
0.2	3.8	GO:0001891	phagocytic cup(GO:0001891)
0.2	10.6	GO:0008021	synaptic vesicle(GO:0008021)
0.2	3.1	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.2	191.9	GO:0005739	mitochondrion(GO:0005739)
0.2	85.8	GO:0048471	perinuclear region of cytoplasm(GO:0048471)
0.2	10.8	GO:0005643	nuclear pore(GO:0005643)
0.2	26.2	GO:0005802	trans-Golgi network(GO:0005802)
0.2	10.8	GO:0043197	dendritic spine(GO:0043197)
0.1	0.6	GO:0036157	outer dynein arm(GO:0036157)
0.1	3.9	GO:0016235	aggresome(GO:0016235)
0.1	13.0	GO:0030427	site of polarized growth(GO:0030427)
0.1	2.1	GO:0043189	NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.1	16.8	GO:0005769	early endosome(GO:0005769)
0.1	2.1	GO:0080008	Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1	20.4	GO:0045202	synapse(GO:0045202)
0.1	3.1	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.1	6.2	GO:0030425	dendrite(GO:0030425)
0.0	0.6	GO:0030126	COPI vesicle coat(GO:0030126)
0.0	1.3	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0	3.7	GO:0031301	integral component of organelle membrane(GO:0031301)
0.0	1.4	GO:0030658	transport vesicle membrane(GO:0030658)
0.0	9.9	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.0	2.1	GO:0001726	ruffle(GO:0001726)
0.0	3.4	GO:0005635	nuclear envelope(GO:0005635)
0.0	1.2	GO:0016591	DNA-directed RNA polymerase II, holoenzyme(GO:0016591)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
22.7	68.2	GO:0004807	triose-phosphate isomerase activity(GO:0004807)
21.3	106.6	GO:0051373	FATZ binding(GO:0051373)
19.5	97.5	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
17.8	53.4	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
15.6	46.7	GO:0051538	3 iron, 4 sulfur cluster binding(GO:0051538)
15.1	90.4	GO:0004470	malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
12.6	37.8	GO:0034485	phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485) inositol tetrakisphosphate phosphatase activity(GO:0052743)
11.4	45.7	GO:0001642	group III metabotropic glutamate receptor activity(GO:0001642)
10.4	31.3	GO:0004724	magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
10.3	31.0	GO:0080130	L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
9.8	39.1	GO:0055100	adiponectin binding(GO:0055100)
9.5	19.0	GO:0008177	succinate dehydrogenase (ubiquinone) activity(GO:0008177)
9.1	27.3	GO:0030899	calcium-dependent ATPase activity(GO:0030899)
9.0	72.1	GO:0008121	ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
8.2	24.6	GO:0004618	phosphoglycerate kinase activity(GO:0004618)
7.9	31.6	GO:0030172	troponin C binding(GO:0030172)
7.0	21.1	GO:0004466	long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
6.6	19.9	GO:0001847	opsonin receptor activity(GO:0001847)
6.5	25.9	GO:0005219	ryanodine-sensitive calcium-release channel activity(GO:0005219)
6.4	31.9	GO:0043532	angiostatin binding(GO:0043532)
6.4	19.1	GO:0072590	N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590)
6.4	25.4	GO:0004449	isocitrate dehydrogenase (NAD+) activity(GO:0004449)
6.3	31.4	GO:0004614	phosphoglucomutase activity(GO:0004614)
5.9	47.0	GO:0034604	pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
5.7	28.7	GO:0004517	nitric-oxide synthase activity(GO:0004517)
4.8	129.9	GO:0008137	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
4.8	14.4	GO:0044736	acid-sensing ion channel activity(GO:0044736)
4.6	18.3	GO:0048039	ubiquinone binding(GO:0048039)
4.3	60.7	GO:0005237	inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
4.2	58.3	GO:0005391	sodium:potassium-exchanging ATPase activity(GO:0005391)
4.0	71.2	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
3.9	62.8	GO:0051371	muscle alpha-actinin binding(GO:0051371)
3.8	3.8	GO:0002134	UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
3.7	11.0	GO:0015254	glycerol channel activity(GO:0015254)
3.6	10.9	GO:0016403	dimethylargininase activity(GO:0016403)
3.6	14.5	GO:0008489	UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity(GO:0008489)
3.5	17.3	GO:0031014	troponin T binding(GO:0031014)
3.3	13.2	GO:0016149	translation release factor activity, codon specific(GO:0016149)
3.2	19.5	GO:0004985	opioid receptor activity(GO:0004985)
3.1	36.9	GO:0102391	decanoate--CoA ligase activity(GO:0102391)
2.8	39.8	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
2.7	80.4	GO:0016676	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
2.6	18.5	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
2.5	12.6	GO:0000213	tRNA-intron endonuclease activity(GO:0000213)
2.4	9.7	GO:1904288	BAT3 complex binding(GO:1904288)
2.4	52.9	GO:0005521	lamin binding(GO:0005521)
2.4	23.7	GO:0015193	L-proline transmembrane transporter activity(GO:0015193)
2.4	9.5	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
2.3	11.4	GO:0086062	voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
2.3	6.9	GO:0047025	3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
2.1	8.5	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
2.1	14.6	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
2.0	18.2	GO:0015266	protein channel activity(GO:0015266)
1.9	40.9	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
1.9	15.3	GO:0004300	enoyl-CoA hydratase activity(GO:0004300)
1.9	11.3	GO:0017040	ceramidase activity(GO:0017040)
1.8	9.1	GO:0004416	hydroxyacylglutathione hydrolase activity(GO:0004416)
1.8	21.1	GO:0030215	semaphorin receptor binding(GO:0030215)
1.7	5.2	GO:0031708	endothelin B receptor binding(GO:0031708)
1.6	47.7	GO:0009055	electron carrier activity(GO:0009055)
1.6	30.7	GO:0008179	adenylate cyclase binding(GO:0008179)
1.6	11.3	GO:0000155	phosphorelay sensor kinase activity(GO:0000155)
1.5	12.2	GO:0015129	lactate transmembrane transporter activity(GO:0015129)
1.5	7.4	GO:0004467	long-chain fatty acid-CoA ligase activity(GO:0004467)
1.5	38.2	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
1.4	4.3	GO:0030156	benzodiazepine receptor binding(GO:0030156)
1.4	5.7	GO:0034432	endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
1.4	30.7	GO:0005112	Notch binding(GO:0005112)
1.4	145.5	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
1.4	10.8	GO:0005049	nuclear export signal receptor activity(GO:0005049)
1.3	42.7	GO:0030332	cyclin binding(GO:0030332)
1.3	9.3	GO:0004111	creatine kinase activity(GO:0004111)
1.3	36.9	GO:0005452	inorganic anion exchanger activity(GO:0005452)
1.2	9.8	GO:0005169	neurotrophin TRKB receptor binding(GO:0005169)
1.2	12.2	GO:0003680	AT DNA binding(GO:0003680)
1.2	24.3	GO:0015288	porin activity(GO:0015288)
1.1	36.9	GO:0019212	phosphatase inhibitor activity(GO:0019212)
1.1	13.1	GO:0005024	transforming growth factor beta-activated receptor activity(GO:0005024)
1.1	8.7	GO:0004705	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
1.1	42.0	GO:0017080	sodium channel regulator activity(GO:0017080)
1.1	8.6	GO:0005095	GTPase inhibitor activity(GO:0005095)
1.1	10.7	GO:0070679	inositol 1,4,5 trisphosphate binding(GO:0070679)
1.0	31.3	GO:0005184	neuropeptide hormone activity(GO:0005184)
1.0	14.6	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
1.0	27.3	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
1.0	29.2	GO:0070064	proline-rich region binding(GO:0070064)
1.0	119.9	GO:0001191	transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191)
1.0	15.1	GO:0022848	acetylcholine-gated cation channel activity(GO:0022848)
1.0	56.0	GO:0019894	kinesin binding(GO:0019894)
1.0	21.8	GO:0008327	methyl-CpG binding(GO:0008327)
1.0	26.9	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.9	47.3	GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.9	25.3	GO:0017134	fibroblast growth factor binding(GO:0017134)
0.8	34.7	GO:0030552	cAMP binding(GO:0030552)
0.8	10.9	GO:0042043	neurexin family protein binding(GO:0042043)
0.8	11.7	GO:0005523	tropomyosin binding(GO:0005523)
0.8	19.2	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.8	10.0	GO:0005527	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.7	19.2	GO:0008395	steroid hydroxylase activity(GO:0008395)
0.7	17.7	GO:0017091	AU-rich element binding(GO:0017091)
0.7	4.7	GO:0070095	fructose-6-phosphate binding(GO:0070095)
0.6	12.2	GO:0005212	structural constituent of eye lens(GO:0005212)
0.6	48.1	GO:0005518	collagen binding(GO:0005518)
0.6	11.8	GO:0008307	structural constituent of muscle(GO:0008307)
0.5	2.2	GO:0050682	AF-2 domain binding(GO:0050682)
0.5	32.6	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
0.5	21.6	GO:0042169	SH2 domain binding(GO:0042169)
0.5	10.4	GO:0005337	nucleoside transmembrane transporter activity(GO:0005337)
0.5	10.3	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.5	7.6	GO:0001222	transcription corepressor binding(GO:0001222)
0.5	5.2	GO:0000340	RNA 7-methylguanosine cap binding(GO:0000340)
0.5	21.3	GO:0015459	potassium channel regulator activity(GO:0015459)
0.5	15.3	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
0.5	108.4	GO:0008022	protein C-terminus binding(GO:0008022)
0.4	37.2	GO:0005178	integrin binding(GO:0005178)
0.4	2.1	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.4	16.1	GO:0005109	frizzled binding(GO:0005109)
0.4	13.2	GO:0005158	insulin receptor binding(GO:0005158)
0.4	3.9	GO:0005132	type I interferon receptor binding(GO:0005132)
0.4	11.8	GO:0001784	phosphotyrosine binding(GO:0001784)
0.4	2.7	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.4	1.5	GO:0016492	nerve growth factor receptor activity(GO:0010465) G-protein coupled neurotensin receptor activity(GO:0016492)
0.4	3.0	GO:0043522	leucine zipper domain binding(GO:0043522)
0.4	19.4	GO:0008138	protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.4	2.9	GO:0004703	G-protein coupled receptor kinase activity(GO:0004703)
0.4	20.9	GO:0015078	hydrogen ion transmembrane transporter activity(GO:0015078)
0.3	4.8	GO:0033038	bitter taste receptor activity(GO:0033038)
0.3	4.5	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.3	11.2	GO:0070888	E-box binding(GO:0070888)
0.3	7.5	GO:0004407	histone deacetylase activity(GO:0004407)
0.3	16.4	GO:0048306	calcium-dependent protein binding(GO:0048306)
0.3	9.6	GO:0004623	phospholipase A2 activity(GO:0004623)
0.3	3.3	GO:0097371	MDM2/MDM4 family protein binding(GO:0097371)
0.3	3.0	GO:0051959	dynein light intermediate chain binding(GO:0051959)
0.3	6.7	GO:0035255	ionotropic glutamate receptor binding(GO:0035255)
0.3	3.8	GO:0070300	phosphatidic acid binding(GO:0070300)
0.3	16.3	GO:0003743	translation initiation factor activity(GO:0003743)
0.2	0.7	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.2	10.6	GO:0016651	oxidoreductase activity, acting on NAD(P)H(GO:0016651)
0.2	3.5	GO:0001056	RNA polymerase III activity(GO:0001056)
0.2	2.3	GO:0045294	alpha-catenin binding(GO:0045294)
0.2	10.5	GO:0005245	voltage-gated calcium channel activity(GO:0005245)
0.2	2.8	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.2	27.3	GO:0051015	actin filament binding(GO:0051015)
0.2	3.1	GO:0004679	AMP-activated protein kinase activity(GO:0004679)
0.2	8.2	GO:0016836	hydro-lyase activity(GO:0016836)
0.2	72.3	GO:0005525	GTP binding(GO:0005525)
0.2	5.9	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.2	6.6	GO:0005484	SNAP receptor activity(GO:0005484)
0.2	2.9	GO:0008301	DNA binding, bending(GO:0008301)
0.2	2.2	GO:1990381	ubiquitin-specific protease binding(GO:1990381)
0.2	5.9	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1	0.7	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.1	9.1	GO:0004004	RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.1	0.4	GO:0004307	ethanolaminephosphotransferase activity(GO:0004307)
0.1	5.2	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.1	1.3	GO:0043996	histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.1	3.2	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1	5.6	GO:0004860	protein kinase inhibitor activity(GO:0004860)
0.1	0.7	GO:0004331	fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.1	0.6	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
0.1	1.3	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1	1.3	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
0.1	0.8	GO:0008484	sulfuric ester hydrolase activity(GO:0008484)
0.1	2.0	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.1	2.5	GO:0019905	syntaxin binding(GO:0019905)
0.1	0.3	GO:0051032	nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.1	1.2	GO:0003899	DNA-directed RNA polymerase activity(GO:0003899)
0.0	2.5	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	0.7	GO:0001594	trace-amine receptor activity(GO:0001594)
0.0	0.4	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	11.8	GO:0004842	ubiquitin-protein transferase activity(GO:0004842)
0.0	4.8	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0	0.5	GO:0071889	14-3-3 protein binding(GO:0071889)
0.0	0.4	GO:0008009	chemokine activity(GO:0008009)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.5	30.7	PID LPA4 PATHWAY	LPA4-mediated signaling events
1.4	92.6	PID CASPASE PATHWAY	Caspase cascade in apoptosis
1.2	16.9	PID ALK2 PATHWAY	ALK2 signaling events
0.9	23.7	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.8	38.7	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.8	11.7	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.7	50.7	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.6	12.4	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.4	7.6	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.4	11.6	PID ILK PATHWAY	Integrin-linked kinase signaling
0.4	8.0	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.3	2.5	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.3	14.5	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
0.3	10.9	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.3	5.2	PID ENDOTHELIN PATHWAY	Endothelins
0.3	11.8	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.3	7.5	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.3	12.3	PID SHP2 PATHWAY	SHP2 signaling
0.3	10.4	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.3	5.6	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
0.3	18.6	PID AP1 PATHWAY	AP-1 transcription factor network
0.3	8.0	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.2	8.5	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.2	6.7	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.2	10.4	NABA COLLAGENS	Genes encoding collagen proteins
0.2	5.9	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.2	2.9	PID IL27 PATHWAY	IL27-mediated signaling events
0.2	12.6	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.2	6.9	PID LKB1 PATHWAY	LKB1 signaling events
0.2	2.2	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.2	3.9	PID CD8 TCR DOWNSTREAM PATHWAY	Downstream signaling in naïve CD8+ T cells
0.2	6.9	PID TNF PATHWAY	TNF receptor signaling pathway
0.1	11.2	WNT SIGNALING	Genes related to Wnt-mediated signal transduction
0.1	6.3	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.1	4.9	PID NOTCH PATHWAY	Notch signaling pathway
0.1	2.1	PID RHODOPSIN PATHWAY	Visual signal transduction: Rods
0.1	2.9	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.1	2.2	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.1	4.5	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events
0.1	4.6	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.1	3.3	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.1	3.3	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.0	1.5	PID P75 NTR PATHWAY	p75(NTR)-mediated signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
6.2	402.9	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
6.1	239.8	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
5.2	78.3	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
5.2	67.1	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
4.6	74.1	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
3.6	60.7	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
2.5	24.9	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
2.4	93.5	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
2.4	93.2	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
2.4	26.1	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
2.2	60.6	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
2.0	36.9	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
2.0	30.7	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
2.0	44.9	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
1.8	70.8	REACTOME AMINE LIGAND BINDING RECEPTORS	Genes involved in Amine ligand-binding receptors
1.7	12.2	REACTOME PYRUVATE METABOLISM	Genes involved in Pyruvate metabolism
1.6	31.4	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
1.5	21.1	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
1.2	33.6	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
1.2	56.6	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
1.0	39.8	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
1.0	30.7	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.9	13.8	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.9	11.0	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.9	15.3	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.9	14.5	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.8	21.9	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.8	15.8	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.8	10.7	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.8	21.8	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.7	29.8	REACTOME NUCLEAR SIGNALING BY ERBB4	Genes involved in Nuclear signaling by ERBB4
0.7	8.5	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.6	19.2	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.6	20.9	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.6	3.6	REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR	Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.6	9.4	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.6	13.4	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.6	20.0	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.5	7.6	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.5	8.7	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.5	17.0	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors
0.5	12.3	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.5	26.4	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.4	11.4	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.4	11.5	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.4	5.2	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.4	9.6	REACTOME ACYL CHAIN REMODELLING OF PE	Genes involved in Acyl chain remodelling of PE
0.4	2.9	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.4	2.5	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.3	11.1	REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	Genes involved in Interactions of Vpr with host cellular proteins
0.3	12.1	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.3	7.5	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.3	3.5	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.3	3.0	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.3	7.5	REACTOME SIGNALING BY NOTCH1	Genes involved in Signaling by NOTCH1
0.3	2.1	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.2	12.2	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.2	4.4	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.2	5.4	REACTOME RNA POL I TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase I Transcription Termination
0.2	2.9	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.2	5.9	REACTOME G ALPHA S SIGNALLING EVENTS	Genes involved in G alpha (s) signalling events
0.2	10.1	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.2	2.8	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.2	19.3	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.2	4.2	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.2	7.2	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1	11.2	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.1	8.9	REACTOME TRAF6 MEDIATED INDUCTION OF NFKB AND MAP KINASES UPON TLR7 8 OR 9 ACTIVATION	Genes involved in TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation
0.1	3.9	REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS	Genes involved in TGF-beta receptor signaling activates SMADs
0.1	6.2	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.1	1.0	REACTOME SIGNALING BY ERBB2	Genes involved in Signaling by ERBB2
0.1	0.7	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.1	1.2	REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING	Genes involved in p75 NTR receptor-mediated signalling
0.1	0.7	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.1	3.4	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.1	0.9	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	1.7	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.0	1.1	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.0	1.5	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	3.4	REACTOME G ALPHA I SIGNALLING EVENTS	Genes involved in G alpha (i) signalling events
0.0	0.2	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events

Results for Ppara

Z-value: 1.80

Motif logo

Transcription factors associated with Ppara

Activity-expression correlation:

Activity profile of Ppara motif

Sorted Z-values of Ppara motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of Ppara

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: