ISMARA results: Pou2f1

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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Pou2f1

Z-value: 1.00

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Transcription factors associated with Pou2f1

Gene Symbol	Gene ID	Gene Info
Pou2f1 NCBI RGD Ensembl	ENSRNOG00000003581	POU class 2 homeobox 1

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Pou2f1	rn6_v1_chr13_-_84217332_84217366	0.48	1.5e-19	Click!

Activity profile of Pou2f1 motif

Sorted Z-values of Pou2f1 motif

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Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr15_+_57241968 Show fit	30.60	ENSRNOT00000082191	Lcp1 NCBI RGD Ensembl Show fit	lymphocyte cytosolic protein 1
chr6_-_143065639 Show fit	30.59	ENSRNOT00000070923	AABR07065827.1 NCBI RGD Ensembl Show fit
chr4_+_106323089 Show fit	29.02	ENSRNOT00000091402	AABR07061134.1 NCBI RGD Ensembl Show fit
chr2_+_223029559 Show fit	27.55	ENSRNOT00000045584	AABR07013111.1 NCBI RGD Ensembl Show fit
chr4_+_98370797 Show fit	24.55	ENSRNOT00000031991	AABR07060872.1 NCBI RGD Ensembl Show fit
chr6_+_139486775 Show fit	23.41	ENSRNOT00000077771	AABR07065699.3 NCBI RGD Ensembl Show fit
chr3_+_16846412 Show fit	23.06	ENSRNOT00000074266	AABR07051551.1 NCBI RGD Ensembl Show fit
chr6_-_142676432 Show fit	22.55	ENSRNOT00000074947	AABR07065815.2 NCBI RGD Ensembl Show fit
chr10_+_45289741 Show fit	21.58	ENSRNOT00000066190	Hist3h2ba NCBI RGD Ensembl Show fit	histone cluster 3, H2ba
chr6_-_142880382 Show fit	20.83	ENSRNOT00000074706 ENSRNOT00000072861	AABR07065821.1 NCBI RGD Ensembl Show fit

Showing 1 to 10 of 200 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of Pou2f1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.6	54.7	GO:0006342	chromatin silencing(GO:0006342)
2.0	30.6	GO:0051764	actin filament network formation(GO:0051639) actin crosslink formation(GO:0051764)
0.3	30.4	GO:0006334	nucleosome assembly(GO:0006334)
0.1	19.5	GO:0007416	synapse assembly(GO:0007416)
4.4	17.8	GO:2000255	negative regulation of male germ cell proliferation(GO:2000255)
4.2	16.8	GO:2001027	negative regulation of endothelial cell chemotaxis(GO:2001027)
3.6	14.4	GO:0051643	endoplasmic reticulum localization(GO:0051643)
2.3	13.7	GO:0002681	somatic diversification of T cell receptor genes(GO:0002568) somatic recombination of T cell receptor gene segments(GO:0002681) T cell receptor V(D)J recombination(GO:0033153)
1.4	13.7	GO:0034983	peptidyl-lysine deacetylation(GO:0034983)
0.0	13.5	GO:0043547	positive regulation of GTPase activity(GO:0043547)

Showing 1 to 10 of 166 entries

Gene overrepresentation in cellular component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.9	85.8	GO:0000786	nucleosome(GO:0000786)
1.3	35.9	GO:0001891	phagocytic cup(GO:0001891)
0.1	24.3	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
1.4	22.7	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.2	22.4	GO:0005814	centriole(GO:0005814)
0.0	18.4	GO:0030424	axon(GO:0030424)
0.0	15.6	GO:0005887	integral component of plasma membrane(GO:0005887)
0.1	15.0	GO:0009897	external side of plasma membrane(GO:0009897)
4.8	14.4	GO:0042642	actomyosin, myosin complex part(GO:0042642)
0.1	13.3	GO:0008076	voltage-gated potassium channel complex(GO:0008076)

Showing 1 to 10 of 85 entries

Gene overrepresentation in molecular function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.2	98.9	GO:0046982	protein heterodimerization activity(GO:0046982)
0.2	76.4	GO:0030246	carbohydrate binding(GO:0030246)
0.0	24.3	GO:0005509	calcium ion binding(GO:0005509)
0.1	23.7	GO:0051015	actin filament binding(GO:0051015)
0.3	17.4	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.3	17.1	GO:0016860	intramolecular oxidoreductase activity(GO:0016860)
5.6	16.8	GO:0031735	CCR10 chemokine receptor binding(GO:0031735)
0.8	14.4	GO:0043008	ATP-dependent protein binding(GO:0043008)
3.3	13.3	GO:0099583	neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.6	12.7	GO:0004033	aldo-keto reductase (NADP) activity(GO:0004033)

Showing 1 to 10 of 121 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	23.4	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.5	21.6	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.3	20.9	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
0.4	17.9	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.4	17.4	PID ARF6 PATHWAY	Arf6 signaling events
0.3	15.9	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.2	15.1	PID NOTCH PATHWAY	Notch signaling pathway
0.3	11.4	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.2	8.8	PID PLK1 PATHWAY	PLK1 signaling events
0.1	8.3	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network

Showing 1 to 10 of 29 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.7	18.5	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.3	17.6	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.8	16.8	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.3	15.8	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.6	14.4	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.1	14.4	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.4	11.8	REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS	Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.2	11.7	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
1.4	11.4	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.2	11.0	REACTOME L1CAM INTERACTIONS	Genes involved in L1CAM interactions

Showing 1 to 10 of 47 entries

Results for Pou2f1

Z-value: 1.00

Motif logo

Transcription factors associated with Pou2f1

Activity-expression correlation:

Activity profile of Pou2f1 motif

Sorted Z-values of Pou2f1 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of Pou2f1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: