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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Nr2f2

Z-value: 1.76

Motif logo

Transcription factors associated with Nr2f2

Gene Symbol Gene ID Gene Info
ENSRNOG00000010308 nuclear receptor subfamily 2, group F, member 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nr2f2rn6_v1_chr1_-_131460473_1314604730.225.2e-05Click!

Activity profile of Nr2f2 motif

Sorted Z-values of Nr2f2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr16_-_32868680 58.55 ENSRNOT00000015974
ENSRNOT00000082392
aminoadipate aminotransferase
chr12_+_943006 57.36 ENSRNOT00000001449
Klotho
chr5_-_137372993 48.33 ENSRNOT00000092823
transmembrane protein 125
chr9_-_88357182 47.70 ENSRNOT00000041176
collagen type IV alpha 4 chain
chrX_-_142131545 40.73 ENSRNOT00000077402
fibroblast growth factor 13
chr16_+_20521956 40.68 ENSRNOT00000026597
pyroglutamyl-peptidase I
chr3_-_2689084 39.83 ENSRNOT00000020926
prostaglandin D2 synthase
chr10_+_92337879 38.88 ENSRNOT00000042984
microtubule-associated protein tau
chr14_-_115052450 38.30 ENSRNOT00000067998
acylphosphatase 2
chr9_-_88356716 38.11 ENSRNOT00000077503
collagen type IV alpha 4 chain
chr2_-_23289266 38.04 ENSRNOT00000061708
betaine-homocysteine S-methyltransferase 2
chr1_+_100131449 36.71 ENSRNOT00000091964
ENSRNOT00000071416
kallikrein 1
chr14_-_106393670 36.49 ENSRNOT00000011429
malate dehydrogenase 1
chr19_+_24701049 35.00 ENSRNOT00000035890
NADH:ubiquinone oxidoreductase subunit B7
chr5_-_137372524 33.65 ENSRNOT00000009061
transmembrane protein 125
chr17_-_417480 31.93 ENSRNOT00000023685
fructose-bisphosphatase 1
chr3_-_9326993 31.67 ENSRNOT00000090137
laminin subunit gamma 3
chr1_-_70235091 31.63 ENSRNOT00000075745
antisense paternally expressed gene 3
chr10_+_15088935 31.41 ENSRNOT00000030273
G protein subunit gamma 13
chr14_+_39154529 30.52 ENSRNOT00000003191
gamma-aminobutyric acid type A receptor alpha4 subunit
chr1_-_81881549 29.34 ENSRNOT00000027497
ATPase Na+/K+ transporting subunit alpha 3
chr1_+_80321585 28.26 ENSRNOT00000022895
creatine kinase, M-type
chr8_+_59507990 28.00 ENSRNOT00000018003
hydroxylysine kinase
chr10_-_103848035 27.01 ENSRNOT00000029001
fatty acid desaturase 6
chr14_+_16491573 26.86 ENSRNOT00000002995
sosondowah ankyrin repeat domain family member B
chr9_+_16647922 26.85 ENSRNOT00000031625
kinesin light chain 4
chr10_-_109909646 26.39 ENSRNOT00000074362
ENSRNOT00000088907
dicarbonyl and L-xylulose reductase
chr6_+_105364668 25.78 ENSRNOT00000009513
ENSRNOT00000087090
tetratricopeptide repeat domain 9
chr1_+_80195532 25.73 ENSRNOT00000022528
reticulon 2
chr1_+_250426158 25.38 ENSRNOT00000067643
APOBEC1 complementation factor
chr9_-_55673704 25.27 ENSRNOT00000066231
ENSRNOT00000081677
transmembrane protein with EGF-like and two follistatin-like domains 2
chr8_-_73164620 25.18 ENSRNOT00000031988
talin 2
chr7_-_12518684 25.02 ENSRNOT00000018691
ENSRNOT00000093426
glutathione peroxidase 4
chrX_-_54303729 24.99 ENSRNOT00000087919
ENSRNOT00000064340
ENSRNOT00000051249
ENSRNOT00000087547
glycerol kinase
chr9_+_16647598 24.88 ENSRNOT00000087413
kinesin light chain 4
chr8_+_82257849 24.44 ENSRNOT00000011963
ENSRNOT00000075708
G protein subunit beta 5
chr1_+_191704311 24.10 ENSRNOT00000024057
sodium channel epithelial 1 gamma subunit
chr1_+_15620653 23.80 ENSRNOT00000017401
microtubule-associated protein 7
chr5_+_147288723 23.75 ENSRNOT00000033285
transmembrane protein 54
chr2_+_17616401 23.33 ENSRNOT00000064991
EGF like repeats and discoidin domains 3
chr10_+_39435227 23.24 ENSRNOT00000042144
ENSRNOT00000077185
prolyl 4-hydroxylase subunit alpha 2
chr1_-_222167447 23.13 ENSRNOT00000028687
peroxiredoxin 5
chr3_+_119014620 22.80 ENSRNOT00000067700
solute carrier family 27 member 2
chr8_+_111209908 22.75 ENSRNOT00000090221
angiomotin like 2
chr5_+_158090173 22.53 ENSRNOT00000088766
ENSRNOT00000079516
ENSRNOT00000092026
taste 1 receptor member 2
chr13_+_75111778 22.16 ENSRNOT00000006924
tumor protein p53 inducible protein 3
chr6_-_133716847 21.85 ENSRNOT00000072399
retrotransposon-like 1
chr20_+_6869767 21.81 ENSRNOT00000000631
ENSRNOT00000086330
ENSRNOT00000093188
ENSRNOT00000093736
similar to GI:13385412-like protein splice form I
chr15_+_33632416 21.41 ENSRNOT00000068212

chr12_-_46920952 21.35 ENSRNOT00000001532
musashi RNA-binding protein 1
chr11_-_25350974 21.26 ENSRNOT00000002187
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr1_+_29413365 21.04 ENSRNOT00000019047
ENSRNOT00000088885
histidine triad nucleotide binding protein 3
chr1_-_265560386 20.97 ENSRNOT00000048592
Kv channel-interacting protein 2-like
chr12_+_48316143 20.91 ENSRNOT00000084511
SV2 related protein
chr10_+_65448950 20.83 ENSRNOT00000082348
ENSRNOT00000037016
RAB34, member RAS oncogene family
chr6_-_105261549 20.75 ENSRNOT00000009122
synaptojanin 2 binding protein
chr3_-_55822551 20.58 ENSRNOT00000082624
LDL receptor related protein 2
chr5_+_4982348 20.50 ENSRNOT00000010369
lactamase, beta 2
chr1_+_262905570 20.18 ENSRNOT00000090765
potassium voltage-gated channel interacting protein 2
chr1_+_141821916 20.13 ENSRNOT00000071574
enoyl-CoA hydratase, short chain 1
chr1_+_219833299 20.11 ENSRNOT00000087432
pyruvate carboxylase
chr3_+_145032200 19.52 ENSRNOT00000068210
synapse differentiation inducing 1
chr18_+_30574627 19.38 ENSRNOT00000060484
protocadherin beta 19
chr1_-_216663720 19.23 ENSRNOT00000078944
ENSRNOT00000077409
cyclin-dependent kinase inhibitor 1C
chr2_+_207271853 18.77 ENSRNOT00000085355
ENSRNOT00000017254
ras homolog family member C
chr17_-_21705773 18.71 ENSRNOT00000078010
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
chr1_-_89539210 18.67 ENSRNOT00000077462
ENSRNOT00000028644
hepsin
chr2_+_23385183 18.64 ENSRNOT00000014860
arylsulfatase B
chr1_-_222189604 18.55 ENSRNOT00000028704
potassium two pore domain channel subfamily K member 4
chr16_+_20691978 18.38 ENSRNOT00000038139
ENSRNOT00000082319
transmembrane protein 59-like
chr2_+_242882306 18.24 ENSRNOT00000013661
DNA-damage-inducible transcript 4-like
chr2_-_144323254 18.21 ENSRNOT00000018780
serine-rich and transmembrane domain containing 1
chr17_-_16695126 17.86 ENSRNOT00000021550
inhibitor of DNA binding 4, HLH protein
chr5_-_99566317 17.62 ENSRNOT00000051028
ENSRNOT00000089235
multiple PDZ domain crumbs cell polarity complex component
chr8_+_48422036 17.36 ENSRNOT00000036051
ubiquitin specific peptidase 2
chr2_+_115678344 17.14 ENSRNOT00000036717
solute carrier family 7, member 14
chr18_-_28444880 17.08 ENSRNOT00000060696
proline rich basic protein 1
chr1_-_220467159 17.07 ENSRNOT00000075365
transmembrane protein 151A
chr15_+_34167945 17.05 ENSRNOT00000032252
capping protein regulator and myosin 1 linker 3
chr17_-_69862110 17.04 ENSRNOT00000058312
aldo-keto reductase family 1, member C-like
chr8_-_49106177 17.03 ENSRNOT00000067558
transmembrane protein 25
chrX_+_26294066 17.03 ENSRNOT00000037862
holocytochrome c synthase
chr2_+_187344056 17.00 ENSRNOT00000025314
nestin
chr17_+_47397558 16.66 ENSRNOT00000085923
ependymin related 1
chr1_+_266530477 16.61 ENSRNOT00000054699
cyclin and CBS domain divalent metal cation transport mediator 2
chr1_+_177048655 16.61 ENSRNOT00000081595
microtubule associated monooxygenase, calponin and LIM domain containing 2
chr7_-_126465723 16.44 ENSRNOT00000021196
wingless-type MMTV integration site family, member 7B
chr19_+_25526751 16.41 ENSRNOT00000083448
calcium voltage-gated channel subunit alpha1 A
chr1_-_42587666 16.38 ENSRNOT00000083225
ENSRNOT00000025355
regulator of G-protein signaling 17
chr5_+_2813131 16.13 ENSRNOT00000009530
somatomedin B and thrombospondin, type 1 domain containing
chr6_+_92229686 15.99 ENSRNOT00000046085
atlastin GTPase 1
chr2_+_266317745 15.66 ENSRNOT00000080305
wntless Wnt ligand secretion mediator
chr5_-_105582375 15.58 ENSRNOT00000083373
solute carrier family 24 member 2
chr2_-_208420163 15.26 ENSRNOT00000021920
ATP synthase subunit b, mitochondrial-like
chrX_+_5825711 15.25 ENSRNOT00000037360
EF-hand domain containing 2
chr3_-_8981362 15.17 ENSRNOT00000086717
carnitine O-acetyltransferase
chr1_-_53038229 15.17 ENSRNOT00000017282
mitochondrial pyruvate carrier 1
chr3_+_160047296 15.01 ENSRNOT00000051590
cAMP-dependent protein kinase inhibitor gamma
chr12_+_40417944 14.98 ENSRNOT00000073125
acyl-CoA dehydrogenase family, member 10
chr13_+_113373578 14.98 ENSRNOT00000009900
plexin A2
chr12_+_47920743 14.80 ENSRNOT00000072511
methylmalonic aciduria (cobalamin deficiency) cblB type
chr2_+_198321142 14.73 ENSRNOT00000028760
synaptic vesicle glycoprotein 2a
chr4_-_6330699 14.71 ENSRNOT00000078077
ENSRNOT00000011814
polypeptide N-acetylgalactosaminyltransferase 11
chr7_+_34533543 14.65 ENSRNOT00000007412
ENSRNOT00000084185
netrin 4
chr18_-_56325095 14.64 ENSRNOT00000025209
solute carrier family 6 member 7
chr2_-_178389608 14.59 ENSRNOT00000013262
electron transfer flavoprotein dehydrogenase
chr13_+_52667969 14.53 ENSRNOT00000084986
ENSRNOT00000050284
troponin T2, cardiac type
chr1_-_56168351 14.48 ENSRNOT00000035125
dishevelled-binding antagonist of beta-catenin 2
chr4_-_79989572 14.46 ENSRNOT00000013264
ENSRNOT00000086453
deafness, autosomal dominant 5 (human)
chr13_-_107831014 14.44 ENSRNOT00000003684
potassium two pore domain channel subfamily K member 2
chr3_+_161425988 14.13 ENSRNOT00000065184
solute carrier family 12 member 5
chr4_+_99753500 14.07 ENSRNOT00000086291
ENSRNOT00000043199
inner membrane mitochondrial protein
chr5_-_166726794 14.03 ENSRNOT00000022799
solute carrier family 25 member 33
chr1_-_112947399 14.03 ENSRNOT00000093306
ENSRNOT00000093259
gamma-aminobutyric acid type A receptor alpha 5 subunit
chr16_-_55002322 13.99 ENSRNOT00000036092
zinc finger, DHHC-type containing 2
chr2_-_179704629 13.97 ENSRNOT00000083361
ENSRNOT00000077941
glutamate ionotropic receptor AMPA type subunit 2
chr6_-_132747828 13.89 ENSRNOT00000005753
solute carrier family 25 member 29
chr20_-_14573519 13.76 ENSRNOT00000001772
RAB36, member RAS oncogene family
chr11_-_38103290 13.61 ENSRNOT00000066413
transmembrane protease, serine 2
chr7_-_117788550 13.46 ENSRNOT00000021775
similar to RIKEN cDNA C030006K11
chr5_-_40867023 13.26 ENSRNOT00000011576
mannosidase, endo-alpha
chr7_-_2786856 13.21 ENSRNOT00000047530
ENSRNOT00000086939
coenzyme Q10A
chrX_-_139464798 13.19 ENSRNOT00000003282
glypican 4
chr16_+_20962227 13.14 ENSRNOT00000027615
solute carrier family 25, member 42
chr3_+_56862691 13.06 ENSRNOT00000087712
glutamate decarboxylase 1
chr1_-_112947162 13.06 ENSRNOT00000014573
ENSRNOT00000083894
gamma-aminobutyric acid type A receptor alpha 5 subunit
chr11_+_83884048 13.00 ENSRNOT00000002376
chloride channel protein 2
chr11_+_83883879 12.98 ENSRNOT00000050927
chloride channel protein 2
chr1_+_221801524 12.92 ENSRNOT00000031227
neurexin 2
chr2_+_98252925 12.91 ENSRNOT00000011579
peroxisomal biogenesis factor 2
chr14_-_9456990 12.90 ENSRNOT00000002918
CDP-diacylglycerol synthase 1
chr6_+_36107147 12.88 ENSRNOT00000006020
retinol dehydrogenase 14 (all-trans/9-cis/11-cis)
chr11_-_64952687 12.87 ENSRNOT00000087892
popeye domain containing 2
chr11_+_86512797 12.85 ENSRNOT00000051680
glycoprotein Ib platelet beta subunit
chr4_+_147692028 12.68 ENSRNOT00000014207
cullin-associated and neddylation-dissociated 2 (putative)
chr9_-_71900044 12.67 ENSRNOT00000020322
isocitrate dehydrogenase (NADP(+)) 1, cytosolic
chr2_+_112868707 12.56 ENSRNOT00000017805
neutral cholesterol ester hydrolase 1
chr5_-_136965191 12.51 ENSRNOT00000056842
ST3 beta-galactoside alpha-2,3-sialyltransferase 3
chr16_-_64716224 12.49 ENSRNOT00000071166
fucosyltransferase 10
chr1_+_102414625 12.44 ENSRNOT00000089488
potassium voltage-gated channel subfamily C member 1
chr10_+_75495817 12.31 ENSRNOT00000013743
CUE domain containing 1
chr1_-_72509431 12.21 ENSRNOT00000071971
similar to isochorismatase domain containing 2
chr5_+_137189473 12.19 ENSRNOT00000056815
hydroxypyruvate isomerase
chr15_-_55424024 12.09 ENSRNOT00000077733
nudix hydrolase 15
chr10_-_57653359 12.08 ENSRNOT00000089638
derlin 2
chr7_+_77763512 12.02 ENSRNOT00000006411
brain and acute leukemia, cytoplasmic
chr3_+_8928534 11.98 ENSRNOT00000088509
ENSRNOT00000065300
mitoguardin 2
chr10_-_56558487 11.92 ENSRNOT00000023256
solute carrier family 2 member 4
chr7_-_12519154 11.70 ENSRNOT00000093376
ENSRNOT00000077681
glutathione peroxidase 4
chrX_-_14910727 11.59 ENSRNOT00000085079
ENSRNOT00000030146
SSX family member 1
chr16_+_81587446 11.36 ENSRNOT00000092680
DCN1, defective in cullin neddylation 1, domain containing 2
chr3_-_114307250 11.26 ENSRNOT00000064592
Src homology 2 domain containing F
chr13_-_105684374 11.09 ENSRNOT00000073142
spermatogenesis associated 17
chr5_-_88629491 11.09 ENSRNOT00000058906
transducin like enhancer of split 1
chr11_+_82862695 11.06 ENSRNOT00000071707
ENSRNOT00000073435
chloride voltage-gated channel 2
chr6_+_50528823 10.96 ENSRNOT00000008321
laminin subunit beta 1
chrX_-_131343853 10.93 ENSRNOT00000038653
DDB1 and CUL4 associated factor 12-like 1
chr16_+_74531564 10.79 ENSRNOT00000078971
solute carrier family 25 member 15
chr5_+_169213115 10.76 ENSRNOT00000013535
nucleolar protein 9
chr1_+_101541266 10.74 ENSRNOT00000028436
hydroxysteroid (17-beta) dehydrogenase 14
chr18_+_53727209 10.73 ENSRNOT00000026706
isochorismatase domain containing 1
chr7_-_136853154 10.70 ENSRNOT00000087376
neural EGFL like 2
chr2_-_52282548 10.65 ENSRNOT00000033627
nicotinamide nucleotide transhydrogenase
chr1_-_24056373 10.65 ENSRNOT00000015566
solute carrier family 2 member 12
chr3_-_2459385 10.63 ENSRNOT00000014080
cysteine rich tail 1
chr2_-_30127269 10.63 ENSRNOT00000023869
CART prepropeptide
chr11_-_70499200 10.61 ENSRNOT00000002439
solute carrier family 12, member 8
chr1_-_2846200 10.58 ENSRNOT00000017688
SAM and SH3 domain containing 1
chr1_+_28301922 10.57 ENSRNOT00000017831
ring finger protein 217
chr4_+_84423653 10.55 ENSRNOT00000012655
chimerin 2
chr5_-_57267002 10.51 ENSRNOT00000011455
Bcl2 associated athanogene 1
chr1_-_204605552 10.46 ENSRNOT00000022904
NK1 homeobox 2
chr1_+_31264755 10.41 ENSRNOT00000028988
NADH dehydrogenase (ubiquinone) Fe-S protein 6
chr1_+_97632473 10.36 ENSRNOT00000023671
V-set and transmembrane domain containing 2B
chrX_-_63961527 10.16 ENSRNOT00000071762
G1 to S phase transition 2
chr15_+_33822730 10.09 ENSRNOT00000067607
similar to dehydrogenase/reductase member 2
chr5_+_24146171 10.04 ENSRNOT00000037547
similar to RIKEN cDNA 2610301B20; EST AI428449
chr7_+_125058897 9.98 ENSRNOT00000016520
SAMM50 sorting and assembly machinery component
chr1_-_99870024 9.90 ENSRNOT00000085556

chr2_+_21931493 9.82 ENSRNOT00000018259
dihydrofolate reductase
chr9_+_92435896 9.80 ENSRNOT00000022901
F-box protein 36
chr3_+_151310598 9.76 ENSRNOT00000092194
matrix metallopeptidase 24
chr1_+_280633938 9.73 ENSRNOT00000012564
empty spiracles homeobox 2
chr5_+_169659188 9.68 ENSRNOT00000066623
nephrocystin 4
chr11_-_64583994 9.39 ENSRNOT00000004289
beta-1,4-galactosyltransferase 4
chr12_-_24710019 9.39 ENSRNOT00000049601
syntaxin 1A
chr2_+_93669765 9.35 ENSRNOT00000045438
solute carrier family 10, member 5
chr3_+_55369214 9.28 ENSRNOT00000067161
nitric oxide synthase trafficking
chr12_+_22082057 9.21 ENSRNOT00000077711
ENSRNOT00000064572
ArfGAP with FG repeats 2
chr3_-_12029877 9.18 ENSRNOT00000022327
solute carrier family 2 member 8
chr2_-_187133993 9.15 ENSRNOT00000019502
platelet endothelial aggregation receptor 1
chr1_+_95397991 9.01 ENSRNOT00000039649
zinc finger protein 939
chr9_-_16647458 9.00 ENSRNOT00000024380
mitochondrial ribosomal protein L2
chr3_+_81814261 8.99 ENSRNOT00000011459
synaptotagmin 13
chr10_-_85084850 8.98 ENSRNOT00000012462
TBK1 binding protein 1
chr3_-_138462063 8.88 ENSRNOT00000065553
ovo-like zinc finger 2
chr1_+_86948918 8.83 ENSRNOT00000084839
sirtuin 2
chr8_-_58542844 8.82 ENSRNOT00000012041
ELMO domain containing 1
chr9_-_101388833 8.82 ENSRNOT00000071817
coiled-coil-helix-coiled-coil-helix domain containing 2
chr6_-_136145837 8.82 ENSRNOT00000015122
creatine kinase B

Network of associatons between targets according to the STRING database.

First level regulatory network of Nr2f2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
19.5 58.6 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
10.0 39.8 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
8.8 26.4 GO:0042732 D-xylose metabolic process(GO:0042732)
8.3 25.0 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
8.0 31.9 GO:0046351 disaccharide biosynthetic process(GO:0046351)
7.7 23.1 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
7.6 22.8 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
7.2 57.4 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
6.7 20.2 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
6.6 86.2 GO:0032836 glomerular basement membrane development(GO:0032836)
6.4 25.7 GO:0010609 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609)
6.2 18.7 GO:0034769 basement membrane disassembly(GO:0034769)
6.2 30.9 GO:0072061 inner medullary collecting duct development(GO:0072061)
6.2 18.5 GO:0071469 cellular response to alkaline pH(GO:0071469)
5.8 40.7 GO:0045196 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
5.5 16.6 GO:0019417 sulfur oxidation(GO:0019417)
5.5 16.4 GO:0021550 medulla oblongata development(GO:0021550) musculoskeletal movement, spinal reflex action(GO:0050883)
5.2 15.7 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
5.1 15.2 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
5.0 20.1 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
5.0 19.8 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
4.9 38.9 GO:0090258 negative regulation of mitochondrial fission(GO:0090258)
4.8 14.5 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
4.8 14.4 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
4.8 38.0 GO:0071267 amino acid salvage(GO:0043102) L-methionine salvage(GO:0071267)
4.5 22.5 GO:0001582 detection of chemical stimulus involved in sensory perception of sweet taste(GO:0001582)
4.5 17.9 GO:0061107 seminal vesicle development(GO:0061107)
4.3 12.9 GO:0060931 sinoatrial node cell development(GO:0060931)
4.3 21.3 GO:0044691 tooth eruption(GO:0044691)
4.3 17.0 GO:0045105 intermediate filament polymerization or depolymerization(GO:0045105)
4.2 12.7 GO:0010265 SCF complex assembly(GO:0010265)
4.2 25.3 GO:0045113 regulation of integrin biosynthetic process(GO:0045113)
3.9 23.2 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
3.8 15.2 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
3.8 7.6 GO:2000813 negative regulation of barbed-end actin filament capping(GO:2000813)
3.8 11.3 GO:0060160 negative regulation of dopamine receptor signaling pathway(GO:0060160)
3.7 11.0 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
3.6 10.8 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448)
3.2 9.7 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
3.2 19.0 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
3.1 18.7 GO:0036438 maintenance of lens transparency(GO:0036438)
3.1 15.5 GO:0006545 glycine biosynthetic process(GO:0006545)
3.1 30.5 GO:2001023 regulation of response to drug(GO:2001023)
3.0 36.5 GO:0006108 malate metabolic process(GO:0006108)
2.9 8.8 GO:2000777 positive regulation of oocyte maturation(GO:1900195) positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
2.9 14.7 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
2.9 29.3 GO:0036376 sodium ion export from cell(GO:0036376)
2.9 22.9 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
2.9 5.7 GO:0061642 chemoattraction of axon(GO:0061642)
2.7 21.6 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
2.7 10.6 GO:0070093 negative regulation of glucagon secretion(GO:0070093)
2.6 10.6 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
2.6 13.1 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
2.5 10.2 GO:0002184 cytoplasmic translational termination(GO:0002184)
2.5 29.4 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
2.4 14.7 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
2.4 12.1 GO:0042262 dGTP catabolic process(GO:0006203) DNA protection(GO:0042262)
2.4 7.1 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
2.3 7.0 GO:0034241 positive regulation of macrophage fusion(GO:0034241) PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
2.3 7.0 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
2.3 20.8 GO:0044351 macropinocytosis(GO:0044351) phagosome-lysosome fusion(GO:0090385)
2.3 25.2 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
2.2 8.9 GO:0060214 endocardium formation(GO:0060214)
2.2 11.1 GO:0060689 cell differentiation involved in salivary gland development(GO:0060689)
2.2 13.1 GO:0015860 purine nucleoside transmembrane transport(GO:0015860)
2.2 10.8 GO:0000066 mitochondrial ornithine transport(GO:0000066)
2.2 12.9 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
2.1 6.4 GO:0036102 leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102) vitamin E metabolic process(GO:0042360) icosanoid catabolic process(GO:1901523) fatty acid derivative catabolic process(GO:1901569)
2.1 12.7 GO:0006102 isocitrate metabolic process(GO:0006102) glyoxylate metabolic process(GO:0046487)
2.1 10.5 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
2.1 6.3 GO:0009644 response to high light intensity(GO:0009644)
2.1 12.4 GO:0021759 globus pallidus development(GO:0021759)
2.1 8.2 GO:1902774 late endosome to lysosome transport(GO:1902774)
1.9 7.7 GO:1902202 proteoglycan catabolic process(GO:0030167) regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
1.9 15.4 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551)
1.7 24.4 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
1.7 8.6 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
1.7 5.0 GO:0080120 prenylated protein catabolic process(GO:0030327) CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
1.7 15.0 GO:0060174 limb bud formation(GO:0060174)
1.7 10.0 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
1.7 5.0 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
1.6 4.9 GO:0042245 RNA repair(GO:0042245)
1.6 4.9 GO:0071934 thiamine transmembrane transport(GO:0071934)
1.6 14.6 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
1.6 9.4 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
1.5 19.5 GO:0097091 synaptic vesicle clustering(GO:0097091)
1.5 14.6 GO:0035524 proline transmembrane transport(GO:0035524)
1.5 1.5 GO:0097033 mitochondrial respiratory chain complex III biogenesis(GO:0097033)
1.4 12.9 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
1.3 4.0 GO:0000105 histidine biosynthetic process(GO:0000105)
1.3 9.2 GO:0043654 recognition of apoptotic cell(GO:0043654)
1.3 6.5 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
1.3 20.6 GO:0045056 transcytosis(GO:0045056)
1.3 23.8 GO:0033327 Leydig cell differentiation(GO:0033327)
1.3 15.0 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
1.2 17.3 GO:0015693 magnesium ion transport(GO:0015693) magnesium ion transmembrane transport(GO:1903830)
1.2 13.6 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
1.2 4.6 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
1.1 8.0 GO:0048311 mitochondrion distribution(GO:0048311)
1.1 2.3 GO:0090210 regulation of establishment of blood-brain barrier(GO:0090210)
1.1 12.1 GO:0070862 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
1.1 2.2 GO:0038189 neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190)
1.1 6.4 GO:0060267 positive regulation of respiratory burst(GO:0060267)
1.0 6.3 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
1.0 3.1 GO:0032900 negative regulation of neurotrophin production(GO:0032900) nerve growth factor production(GO:0032902) negative regulation of receptor catabolic process(GO:2000645)
1.0 17.4 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
1.0 31.7 GO:0035428 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
1.0 38.7 GO:0002675 positive regulation of acute inflammatory response(GO:0002675)
1.0 14.7 GO:0014052 regulation of gamma-aminobutyric acid secretion(GO:0014052)
1.0 18.6 GO:0051597 response to methylmercury(GO:0051597)
1.0 3.9 GO:0071442 RNA 5'-end processing(GO:0000966) regulation of histone H3-K14 acetylation(GO:0071440) positive regulation of histone H3-K14 acetylation(GO:0071442)
1.0 9.8 GO:0044331 cell-cell adhesion mediated by cadherin(GO:0044331)
1.0 10.7 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.9 11.4 GO:0042407 cristae formation(GO:0042407)
0.9 7.6 GO:0032308 positive regulation of prostaglandin secretion(GO:0032308)
0.9 17.0 GO:0017004 cytochrome complex assembly(GO:0017004)
0.9 28.3 GO:0060384 innervation(GO:0060384)
0.9 15.9 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.9 11.1 GO:2000811 negative regulation of anoikis(GO:2000811)
0.9 5.5 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.9 12.5 GO:0036065 fucosylation(GO:0036065)
0.9 5.3 GO:0048597 post-embryonic camera-type eye morphogenesis(GO:0048597)
0.9 7.9 GO:0034651 cortisol metabolic process(GO:0034650) cortisol biosynthetic process(GO:0034651)
0.8 24.4 GO:0014002 astrocyte development(GO:0014002)
0.8 7.5 GO:1902414 protein localization to cell junction(GO:1902414)
0.8 6.7 GO:0090261 positive regulation of inclusion body assembly(GO:0090261)
0.8 13.2 GO:1901663 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.8 36.7 GO:0006749 glutathione metabolic process(GO:0006749)
0.8 5.5 GO:0048496 maintenance of organ identity(GO:0048496)
0.7 21.3 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.7 3.5 GO:0072733 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.7 26.0 GO:0065002 intracellular protein transmembrane transport(GO:0065002)
0.7 32.6 GO:0090505 wound healing, spreading of cells(GO:0044319) epiboly involved in wound healing(GO:0090505)
0.7 2.7 GO:0060856 establishment of blood-brain barrier(GO:0060856)
0.7 26.0 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.7 5.3 GO:0006776 vitamin A metabolic process(GO:0006776)
0.6 8.8 GO:1900037 regulation of cellular response to hypoxia(GO:1900037)
0.6 10.5 GO:0001675 acrosome assembly(GO:0001675)
0.6 2.5 GO:0043418 homocysteine catabolic process(GO:0043418)
0.6 3.6 GO:1903862 positive regulation of oxidative phosphorylation(GO:1903862)
0.6 3.6 GO:0009912 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.6 3.6 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.6 6.5 GO:0060013 righting reflex(GO:0060013)
0.6 2.9 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.6 2.9 GO:0043570 maintenance of DNA repeat elements(GO:0043570)
0.6 6.8 GO:0001778 plasma membrane repair(GO:0001778)
0.6 12.5 GO:0097503 sialylation(GO:0097503)
0.6 7.8 GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060)
0.6 10.0 GO:0008053 mitochondrial fusion(GO:0008053)
0.5 9.7 GO:0021542 dentate gyrus development(GO:0021542)
0.5 5.6 GO:0043584 nose development(GO:0043584)
0.5 4.5 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.5 1.5 GO:1901662 phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662)
0.5 5.2 GO:0033603 positive regulation of dopamine secretion(GO:0033603)
0.5 14.0 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.4 31.0 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.4 10.7 GO:0006706 steroid catabolic process(GO:0006706)
0.4 4.0 GO:0009650 UV protection(GO:0009650)
0.4 6.2 GO:0090201 negative regulation of release of cytochrome c from mitochondria(GO:0090201)
0.4 20.1 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.4 1.2 GO:0048014 Tie signaling pathway(GO:0048014)
0.4 1.2 GO:0090283 regulation of protein glycosylation in Golgi(GO:0090283)
0.4 12.9 GO:0042572 retinol metabolic process(GO:0042572)
0.4 9.4 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.4 24.3 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.4 2.6 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.4 2.9 GO:1901642 nucleoside transmembrane transport(GO:1901642)
0.4 16.0 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.4 27.7 GO:0050909 sensory perception of taste(GO:0050909)
0.3 10.8 GO:0060292 long term synaptic depression(GO:0060292)
0.3 4.3 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.3 13.1 GO:0006739 NADP metabolic process(GO:0006739)
0.3 1.5 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.3 3.0 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.3 2.5 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.3 3.3 GO:1901897 regulation of relaxation of cardiac muscle(GO:1901897)
0.3 1.9 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.3 12.6 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.3 3.2 GO:0033141 regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033139) positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.3 5.4 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.2 2.9 GO:0061051 positive regulation of cell growth involved in cardiac muscle cell development(GO:0061051)
0.2 16.3 GO:1901379 regulation of potassium ion transmembrane transport(GO:1901379)
0.2 7.7 GO:0009268 response to pH(GO:0009268)
0.2 2.7 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.2 3.6 GO:0006198 cAMP catabolic process(GO:0006198)
0.2 5.2 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.2 1.9 GO:0003417 growth plate cartilage development(GO:0003417)
0.2 3.1 GO:0031581 hemidesmosome assembly(GO:0031581)
0.2 1.7 GO:0006777 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.2 1.8 GO:0006390 DNA-templated transcription, termination(GO:0006353) transcription from mitochondrial promoter(GO:0006390)
0.2 8.1 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 1.8 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.1 4.4 GO:0018345 protein palmitoylation(GO:0018345)
0.1 19.4 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 6.1 GO:0032543 mitochondrial translation(GO:0032543)
0.1 1.5 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.1 3.4 GO:0040020 regulation of meiotic nuclear division(GO:0040020)
0.1 6.2 GO:0016126 sterol biosynthetic process(GO:0016126)
0.1 12.7 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.1 1.4 GO:0045217 cell-cell junction maintenance(GO:0045217)
0.1 5.2 GO:0042775 mitochondrial ATP synthesis coupled electron transport(GO:0042775)
0.1 1.7 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.1 1.5 GO:0019532 oxalate transport(GO:0019532)
0.1 2.8 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.1 0.2 GO:0006004 fucose metabolic process(GO:0006004)
0.1 3.2 GO:0030195 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.1 4.2 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.1 0.4 GO:0060449 bud elongation involved in lung branching(GO:0060449)
0.1 5.6 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.1 6.5 GO:0070301 cellular response to hydrogen peroxide(GO:0070301)
0.1 8.5 GO:0050796 regulation of insulin secretion(GO:0050796)
0.1 0.8 GO:0033599 regulation of mammary gland epithelial cell proliferation(GO:0033599)
0.0 1.5 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 3.2 GO:0033574 response to testosterone(GO:0033574)
0.0 5.7 GO:0050773 regulation of dendrite development(GO:0050773)
0.0 0.5 GO:0042026 protein refolding(GO:0042026)
0.0 4.0 GO:0071805 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0 2.3 GO:0042552 myelination(GO:0042552)
0.0 2.8 GO:0008585 female gonad development(GO:0008585)
0.0 3.6 GO:0006814 sodium ion transport(GO:0006814)
0.0 0.6 GO:0036465 synaptic vesicle recycling(GO:0036465)
0.0 0.3 GO:0045124 regulation of bone resorption(GO:0045124)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
10.7 85.8 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
9.7 38.9 GO:0045298 tubulin complex(GO:0045298)
5.8 23.2 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
4.9 29.3 GO:0044326 dendritic spine neck(GO:0044326)
4.5 22.5 GO:1903768 sweet taste receptor complex(GO:1903767) taste receptor complex(GO:1903768)
4.0 12.0 GO:0045203 intrinsic component of cell outer membrane(GO:0031230) integral component of cell outer membrane(GO:0045203)
3.6 14.5 GO:1990584 cardiac Troponin complex(GO:1990584)
3.6 25.4 GO:0045293 mRNA editing complex(GO:0045293)
2.7 11.0 GO:0005607 laminin-1 complex(GO:0005606) laminin-2 complex(GO:0005607) laminin-10 complex(GO:0043259)
2.5 10.2 GO:0018444 translation release factor complex(GO:0018444)
2.5 57.6 GO:1902711 GABA-A receptor complex(GO:1902711)
2.5 17.3 GO:0061617 MICOS complex(GO:0061617)
2.3 4.6 GO:1990246 uniplex complex(GO:1990246)
2.3 16.0 GO:0000137 Golgi cis cisterna(GO:0000137)
2.1 6.4 GO:0005899 insulin receptor complex(GO:0005899)
2.0 38.7 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
2.0 12.1 GO:0005785 signal recognition particle receptor complex(GO:0005785)
2.0 10.0 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
1.9 15.3 GO:0005638 lamin filament(GO:0005638)
1.9 7.7 GO:1990745 EARP complex(GO:1990745)
1.9 9.4 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
1.8 14.4 GO:0044305 calyx of Held(GO:0044305)
1.7 6.8 GO:0030906 retromer, cargo-selective complex(GO:0030906)
1.5 7.7 GO:0043625 delta DNA polymerase complex(GO:0043625)
1.4 55.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
1.3 25.2 GO:0005916 fascia adherens(GO:0005916)
1.3 26.5 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
1.3 3.9 GO:1990923 PET complex(GO:1990923)
1.2 29.3 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
1.2 42.2 GO:0032590 dendrite membrane(GO:0032590)
1.2 14.0 GO:0098839 postsynaptic density membrane(GO:0098839)
1.2 23.1 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
1.1 29.3 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
1.1 8.7 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
1.1 7.6 GO:0071203 WASH complex(GO:0071203)
1.0 24.1 GO:0034706 sodium channel complex(GO:0034706)
0.9 5.6 GO:0005879 axonemal microtubule(GO:0005879)
0.9 2.8 GO:0005594 collagen type IX trimer(GO:0005594)
0.9 25.7 GO:0098827 endoplasmic reticulum subcompartment(GO:0098827)
0.9 11.9 GO:0032593 insulin-responsive compartment(GO:0032593)
0.9 5.5 GO:1990696 stereocilia ankle link complex(GO:0002142) USH2 complex(GO:1990696)
0.9 2.7 GO:0061689 tricellular tight junction(GO:0061689)
0.8 3.2 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.8 40.2 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.8 51.7 GO:0005871 kinesin complex(GO:0005871)
0.8 69.1 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.8 6.1 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.7 9.7 GO:0097470 ribbon synapse(GO:0097470)
0.7 15.3 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.7 5.1 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.7 70.5 GO:0005604 basement membrane(GO:0005604)
0.7 6.7 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.7 33.6 GO:0014704 intercalated disc(GO:0014704)
0.6 5.1 GO:0005869 dynactin complex(GO:0005869)
0.6 5.6 GO:0000813 ESCRT I complex(GO:0000813)
0.6 25.5 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.6 5.0 GO:0000815 ESCRT III complex(GO:0000815)
0.6 53.2 GO:0031985 Golgi cisterna(GO:0031985)
0.6 5.8 GO:0005641 nuclear envelope lumen(GO:0005641)
0.6 1.7 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.5 54.0 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.5 13.1 GO:0060077 inhibitory synapse(GO:0060077)
0.5 5.0 GO:0005798 Golgi-associated vesicle(GO:0005798)
0.5 9.8 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.5 4.2 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.4 4.0 GO:0005796 Golgi lumen(GO:0005796)
0.4 26.4 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.4 24.0 GO:0005844 polysome(GO:0005844)
0.4 40.9 GO:0034705 potassium channel complex(GO:0034705)
0.4 6.3 GO:0034709 methylosome(GO:0034709)
0.4 10.7 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507) endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.4 3.2 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.4 16.6 GO:0070469 respiratory chain(GO:0070469)
0.4 5.4 GO:0043202 lysosomal lumen(GO:0043202)
0.4 109.0 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.4 12.6 GO:0055038 recycling endosome membrane(GO:0055038)
0.4 7.0 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.4 2.6 GO:0048500 signal recognition particle(GO:0048500)
0.4 10.0 GO:0097546 ciliary base(GO:0097546)
0.4 16.5 GO:0031901 early endosome membrane(GO:0031901)
0.3 9.2 GO:0001891 phagocytic cup(GO:0001891)
0.3 2.2 GO:0097443 sorting endosome(GO:0097443)
0.3 3.0 GO:0072546 ER membrane protein complex(GO:0072546)
0.3 23.5 GO:0031526 brush border membrane(GO:0031526)
0.3 5.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.3 25.7 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.3 2.9 GO:0032300 mismatch repair complex(GO:0032300)
0.3 10.5 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.3 2.8 GO:0044232 organelle membrane contact site(GO:0044232)
0.3 100.5 GO:0045177 apical part of cell(GO:0045177)
0.3 8.8 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.2 21.8 GO:0043204 perikaryon(GO:0043204)
0.2 19.7 GO:0042383 sarcolemma(GO:0042383)
0.2 1.5 GO:0071986 Ragulator complex(GO:0071986)
0.2 258.0 GO:0005739 mitochondrion(GO:0005739)
0.2 10.7 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.2 13.2 GO:0031225 anchored component of membrane(GO:0031225)
0.2 14.1 GO:0030496 midbody(GO:0030496)
0.2 62.7 GO:0031012 extracellular matrix(GO:0031012)
0.2 2.8 GO:0001520 outer dense fiber(GO:0001520)
0.1 0.4 GO:0071148 TEAD-1-YAP complex(GO:0071148) TEAD-2-YAP complex(GO:0071149)
0.1 2.5 GO:0000145 exocyst(GO:0000145)
0.1 14.9 GO:0001726 ruffle(GO:0001726)
0.1 12.2 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 2.9 GO:0031902 late endosome membrane(GO:0031902)
0.1 2.0 GO:0001772 immunological synapse(GO:0001772)
0.1 0.4 GO:0032437 cuticular plate(GO:0032437)
0.1 3.7 GO:0005811 lipid particle(GO:0005811)
0.1 6.9 GO:0005814 centriole(GO:0005814)
0.1 13.5 GO:0098793 presynapse(GO:0098793)
0.1 1.8 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 1.5 GO:0005902 microvillus(GO:0005902)
0.0 3.5 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 1.2 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 2.2 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 6.9 GO:0000139 Golgi membrane(GO:0000139)
0.0 0.6 GO:0048475 membrane coat(GO:0030117) coated membrane(GO:0048475)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
19.1 57.4 GO:0004566 beta-glucuronidase activity(GO:0004566)
14.6 58.6 GO:0016212 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
9.7 38.9 GO:0099609 microtubule lateral binding(GO:0099609)
9.1 36.5 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
8.3 25.0 GO:0004370 glycerol kinase activity(GO:0004370)
7.4 22.2 GO:1902379 chemoattractant activity involved in axon guidance(GO:1902379)
6.7 20.1 GO:0004736 pyruvate carboxylase activity(GO:0004736)
6.2 18.5 GO:0097603 temperature-gated ion channel activity(GO:0097603)
5.8 46.6 GO:0008172 S-methyltransferase activity(GO:0008172)
5.8 23.2 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
5.8 23.1 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
5.6 22.5 GO:0003842 1-pyrroline-5-carboxylate dehydrogenase activity(GO:0003842)
5.3 37.1 GO:0004111 creatine kinase activity(GO:0004111)
5.2 20.7 GO:0070699 type II activin receptor binding(GO:0070699)
4.7 18.7 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
4.6 27.8 GO:0048039 ubiquinone binding(GO:0048039)
4.6 36.7 GO:0008430 selenium binding(GO:0008430)
4.3 12.9 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
4.2 12.7 GO:0051990 (R)-2-hydroxyglutarate dehydrogenase activity(GO:0051990)
4.0 20.2 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
4.0 12.1 GO:0035539 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
3.9 15.7 GO:0031852 mu-type opioid receptor binding(GO:0031852)
3.7 40.7 GO:0008242 omega peptidase activity(GO:0008242)
3.7 22.2 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
3.6 14.5 GO:0030172 troponin C binding(GO:0030172)
3.6 10.7 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
3.5 10.5 GO:0001565 phorbol ester receptor activity(GO:0001565)
3.4 20.6 GO:0042954 lipoprotein transporter activity(GO:0042954)
3.1 9.4 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
3.1 12.5 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
3.0 15.2 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
2.9 8.8 GO:0042903 tubulin deacetylase activity(GO:0042903)
2.9 14.4 GO:0022841 potassium ion leak channel activity(GO:0022841)
2.9 31.4 GO:0031681 G-protein beta-subunit binding(GO:0031681)
2.8 14.0 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
2.7 10.8 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
2.7 24.1 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
2.7 18.6 GO:0004065 arylsulfatase activity(GO:0004065)
2.6 13.1 GO:0051185 adenosine-diphosphatase activity(GO:0043262) coenzyme transporter activity(GO:0051185)
2.6 13.1 GO:0004351 glutamate decarboxylase activity(GO:0004351)
2.5 20.1 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
2.5 9.8 GO:0051870 methotrexate binding(GO:0051870)
2.3 31.9 GO:0016208 AMP binding(GO:0016208)
2.3 22.8 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
2.2 6.7 GO:0031531 thyrotropin-releasing hormone receptor binding(GO:0031531)
2.2 15.6 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
2.2 57.6 GO:0004890 GABA-A receptor activity(GO:0004890)
2.2 12.9 GO:0097109 neuroligin family protein binding(GO:0097109)
2.1 6.4 GO:0052871 leukotriene-B4 20-monooxygenase activity(GO:0050051) tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871)
2.1 29.3 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391) D1 dopamine receptor binding(GO:0031748)
2.1 12.5 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
2.1 24.7 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
1.9 17.3 GO:0031995 insulin-like growth factor II binding(GO:0031995)
1.9 5.7 GO:0008732 threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
1.9 15.2 GO:0016413 O-acetyltransferase activity(GO:0016413)
1.9 35.6 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
1.8 14.7 GO:0043237 laminin-1 binding(GO:0043237)
1.8 62.9 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor(GO:0016655)
1.7 17.0 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
1.6 4.9 GO:0015234 thiamine transmembrane transporter activity(GO:0015234)
1.6 8.0 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
1.6 9.4 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
1.6 18.7 GO:0070008 serine-type exopeptidase activity(GO:0070008)
1.5 98.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
1.5 7.6 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
1.5 44.4 GO:0005501 retinoid binding(GO:0005501)
1.5 14.6 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
1.4 27.4 GO:0032794 GTPase activating protein binding(GO:0032794)
1.4 17.0 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
1.4 11.3 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
1.4 19.2 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
1.4 15.0 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
1.4 19.1 GO:0005351 sugar:proton symporter activity(GO:0005351)
1.3 10.8 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
1.3 14.7 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
1.3 11.9 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
1.3 17.2 GO:0017154 semaphorin receptor activity(GO:0017154)
1.2 20.8 GO:0017160 Ral GTPase binding(GO:0017160)
1.2 12.2 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
1.2 4.9 GO:0035514 DNA demethylase activity(GO:0035514) oxidative RNA demethylase activity(GO:0035515)
1.2 6.1 GO:0043532 angiostatin binding(GO:0043532)
1.2 12.9 GO:0008106 alcohol dehydrogenase (NADP+) activity(GO:0008106)
1.2 17.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
1.0 12.6 GO:0042301 phosphate ion binding(GO:0042301)
1.0 4.2 GO:1904288 BAT3 complex binding(GO:1904288)
1.0 40.7 GO:0048487 beta-tubulin binding(GO:0048487)
1.0 21.4 GO:0008266 poly(U) RNA binding(GO:0008266)
1.0 4.0 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
1.0 3.9 GO:0034584 piRNA binding(GO:0034584)
1.0 16.4 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
1.0 7.6 GO:0004565 beta-galactosidase activity(GO:0004565)
1.0 2.9 GO:0032139 dinucleotide insertion or deletion binding(GO:0032139) single guanine insertion binding(GO:0032142)
0.9 9.4 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.9 15.0 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.8 15.3 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.8 10.2 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.8 6.5 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.8 5.3 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.8 16.6 GO:0071949 FAD binding(GO:0071949)
0.7 16.1 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.7 7.8 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.7 2.8 GO:0097108 hedgehog family protein binding(GO:0097108)
0.7 13.2 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.7 13.3 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.6 8.4 GO:0070097 delta-catenin binding(GO:0070097)
0.6 2.6 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.6 51.7 GO:0003777 microtubule motor activity(GO:0003777)
0.6 3.6 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.6 8.2 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.6 7.9 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.5 9.8 GO:0015215 nucleotide transmembrane transporter activity(GO:0015215)
0.5 37.0 GO:0003727 single-stranded RNA binding(GO:0003727)
0.5 6.5 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.5 12.4 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.5 2.5 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.5 16.5 GO:0030552 cAMP binding(GO:0030552)
0.5 12.0 GO:0030332 cyclin binding(GO:0030332)
0.5 5.5 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.4 4.3 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.4 3.8 GO:0004526 ribonuclease P activity(GO:0004526)
0.4 2.9 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.4 44.1 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.4 3.2 GO:0005132 type I interferon receptor binding(GO:0005132)
0.4 5.0 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.4 10.6 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.3 1.0 GO:0031714 C5a anaphylatoxin chemotactic receptor binding(GO:0031714)
0.3 31.0 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.3 4.4 GO:0048406 nerve growth factor binding(GO:0048406)
0.3 2.9 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.3 13.6 GO:0005044 scavenger receptor activity(GO:0005044)
0.3 6.3 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.3 5.2 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.3 6.3 GO:0008327 methyl-CpG binding(GO:0008327)
0.2 1.4 GO:1901612 cardiolipin binding(GO:1901612)
0.2 45.1 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.2 7.1 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.2 10.6 GO:0050661 NADP binding(GO:0050661)
0.2 15.1 GO:0035254 glutamate receptor binding(GO:0035254)
0.2 14.1 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.2 1.2 GO:0017040 ceramidase activity(GO:0017040)
0.2 2.1 GO:0005000 vasopressin receptor activity(GO:0005000)
0.2 3.6 GO:0005112 Notch binding(GO:0005112)
0.2 9.6 GO:0005080 protein kinase C binding(GO:0005080)
0.2 8.0 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.2 2.0 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.2 7.4 GO:0050840 extracellular matrix binding(GO:0050840)
0.2 24.0 GO:0000149 SNARE binding(GO:0000149)
0.1 4.4 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 12.5 GO:0005178 integrin binding(GO:0005178)
0.1 2.5 GO:0008301 DNA binding, bending(GO:0008301)
0.1 35.9 GO:0003924 GTPase activity(GO:0003924)
0.1 5.5 GO:0017022 myosin binding(GO:0017022)
0.1 9.8 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 3.3 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 2.9 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.1 1.5 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 2.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 5.0 GO:0051087 chaperone binding(GO:0051087)
0.1 0.3 GO:0042015 interleukin-20 binding(GO:0042015)
0.1 8.5 GO:0031072 heat shock protein binding(GO:0031072)
0.1 2.5 GO:0004177 aminopeptidase activity(GO:0004177)
0.1 0.3 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.1 1.5 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 2.2 GO:0015459 potassium channel regulator activity(GO:0015459)
0.1 4.4 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.1 1.3 GO:0017025 TBP-class protein binding(GO:0017025)
0.1 1.9 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 3.6 GO:0015293 symporter activity(GO:0015293)
0.0 0.9 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 1.3 GO:0043022 ribosome binding(GO:0043022)
0.0 1.3 GO:0051213 dioxygenase activity(GO:0051213)
0.0 1.0 GO:0043130 ubiquitin binding(GO:0043130)
0.0 5.3 GO:0005549 odorant binding(GO:0005549)
0.0 0.2 GO:0016866 intramolecular transferase activity(GO:0016866)
0.0 0.8 GO:0005262 calcium channel activity(GO:0005262)
0.0 5.6 GO:0005509 calcium ion binding(GO:0005509)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
3.6 46.5 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
2.7 133.1 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
1.4 40.0 PID CONE PATHWAY Visual signal transduction: Cones
1.3 5.3 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.9 20.6 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.8 22.2 PID WNT SIGNALING PATHWAY Wnt signaling network
0.6 18.8 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.6 18.3 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.6 24.8 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.6 4.6 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.6 11.3 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.5 17.3 PID NCADHERIN PATHWAY N-cadherin signaling events
0.3 11.1 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.3 8.8 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.3 17.1 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.3 3.3 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.2 13.6 PID AR PATHWAY Coregulation of Androgen receptor activity
0.2 27.1 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.2 5.2 PID HNF3A PATHWAY FOXA1 transcription factor network
0.2 10.5 PID AP1 PATHWAY AP-1 transcription factor network
0.1 7.0 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.1 28.1 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 19.4 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 1.3 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.1 2.8 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.1 1.0 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.1 3.1 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.1 2.5 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.1 1.1 PID P73PATHWAY p73 transcription factor network
0.0 1.7 PID E2F PATHWAY E2F transcription factor network
0.0 1.2 PID SHP2 PATHWAY SHP2 signaling
0.0 5.6 NABA MATRISOME ASSOCIATED Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors
0.0 0.4 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.3 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
6.5 58.6 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
3.4 57.6 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
2.6 26.4 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
2.5 33.0 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
2.4 55.9 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
2.3 50.6 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
2.2 96.1 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
2.2 88.5 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
1.9 31.7 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
1.8 47.8 REACTOME FGFR LIGAND BINDING AND ACTIVATION Genes involved in FGFR ligand binding and activation
1.7 51.7 REACTOME KINESINS Genes involved in Kinesins
1.4 20.1 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
1.4 32.9 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
1.3 36.7 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
1.2 12.8 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
1.0 22.5 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
1.0 16.5 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
1.0 17.2 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.9 19.1 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.9 22.4 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.8 54.8 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.8 12.5 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.8 10.6 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.8 14.6 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.7 14.0 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.7 8.0 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.6 9.4 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.6 20.6 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.5 18.8 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.5 16.4 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.5 13.3 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.5 12.9 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.5 22.5 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.4 5.2 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.4 14.7 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.4 6.4 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.4 7.7 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.4 6.3 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.4 6.1 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.4 7.6 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.3 5.1 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.3 15.9 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.3 3.6 REACTOME SIGNALING BY NOTCH4 Genes involved in Signaling by NOTCH4
0.3 11.3 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.3 21.3 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.3 29.7 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.3 14.2 REACTOME REGULATION OF INSULIN SECRETION Genes involved in Regulation of Insulin Secretion
0.3 3.6 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.2 18.4 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.2 1.7 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.2 2.4 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.2 5.0 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.2 3.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.2 39.3 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.2 1.3 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.2 6.2 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.2 3.7 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 2.3 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 2.5 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 11.3 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.1 2.0 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.1 2.5 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 4.5 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.1 1.0 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 1.2 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 4.4 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.0 2.1 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 1.8 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 1.6 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 1.2 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.3 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.3 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling