ISMARA results: Nr2f1

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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Nr2f1_Nr4a1

Z-value: 1.37

Motif logo

Transcription factors associated with Nr2f1_Nr4a1

Gene Symbol	Gene ID	Gene Info
Nr2f1 NCBI RGD Ensembl	ENSRNOG00000014795	nuclear receptor subfamily 2, group F, member 1
Nr4a1 NCBI RGD Ensembl	ENSRNOG00000007607	nuclear receptor subfamily 4, group A, member 1

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Nr4a1	rn6_v1_chr7_+_142912316_142912316	-0.27	6.4e-07	Click!
Nr2f1	rn6_v1_chr2_-_5579894_5579894	-0.03	6.3e-01	Click!

Activity profile of Nr2f1_Nr4a1 motif

Sorted Z-values of Nr2f1_Nr4a1 motif

Top targets:

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr8_-_50531423 Show fit	83.11	ENSRNOT00000090985 ENSRNOT00000074942	Apoc3 NCBI RGD Ensembl Show fit	apolipoprotein C3
chr2_-_243407608 Show fit	52.15	ENSRNOT00000014631	Mttp NCBI RGD Ensembl Show fit	microsomal triglyceride transfer protein
chr5_+_118743632 Show fit	47.87	ENSRNOT00000013785	Pgm1 NCBI RGD Ensembl Show fit	phosphoglucomutase 1
chr2_-_178389608 Show fit	47.69	ENSRNOT00000013262	Etfdh NCBI RGD Ensembl Show fit	electron transfer flavoprotein dehydrogenase
chr10_+_63659085 Show fit	46.95	ENSRNOT00000005039	Rilp NCBI RGD Ensembl Show fit	Rab interacting lysosomal protein
chr17_-_66397653 Show fit	46.23	ENSRNOT00000024098	Actn2 NCBI RGD Ensembl Show fit	actinin alpha 2
chr2_-_23256158 Show fit	45.75	ENSRNOT00000015336	Bhmt NCBI RGD Ensembl Show fit	betaine-homocysteine S-methyltransferase
chrX_-_23144324 Show fit	45.34	ENSRNOT00000000178 ENSRNOT00000081239	Pfkfb1 NCBI RGD Ensembl Show fit	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr19_-_56677084 Show fit	43.77	ENSRNOT00000024084	Acta1 NCBI RGD Ensembl Show fit	actin, alpha 1, skeletal muscle
chr3_-_60813869 Show fit	41.06	ENSRNOT00000058234	Atp5g3 NCBI RGD Ensembl Show fit	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)
chr12_-_48238887 Show fit	38.88	ENSRNOT00000078868	Acacb NCBI RGD Ensembl Show fit	acetyl-CoA carboxylase beta
chr11_+_83868655 Show fit	38.71	ENSRNOT00000072402	NEWGENE_621438 NCBI RGD Ensembl Show fit	thrombopoietin
chr17_+_22620721 Show fit	37.81	ENSRNOT00000019478	Adtrp NCBI RGD Ensembl Show fit	androgen-dependent TFPI-regulating protein
chr2_-_140464607 Show fit	36.03	ENSRNOT00000058190	Ndufc1 NCBI RGD Ensembl Show fit	NADH:ubiquinone oxidoreductase subunit C1
chr5_+_119097715 Show fit	35.51	ENSRNOT00000045987	Ror1 NCBI RGD Ensembl Show fit	receptor tyrosine kinase-like orphan receptor 1
chr3_+_171213936 Show fit	34.51	ENSRNOT00000031586	Pck1 NCBI RGD Ensembl Show fit	phosphoenolpyruvate carboxykinase 1
chr1_+_31545631 Show fit	33.98	ENSRNOT00000018336	Sdha NCBI RGD Ensembl Show fit	succinate dehydrogenase complex flavoprotein subunit A
chr10_+_61432819 Show fit	33.98	ENSRNOT00000003687 ENSRNOT00000092478	Cluh NCBI RGD Ensembl Show fit	clustered mitochondria homolog
chr1_-_141579871 Show fit	33.82	ENSRNOT00000020002	Anpep NCBI RGD Ensembl Show fit	alanyl aminopeptidase, membrane
chr2_+_119139717 Show fit	33.53	ENSRNOT00000016051	Ndufb5 NCBI RGD Ensembl Show fit	NADH:ubiquinone oxidoreductase subunit B5
chr6_+_8284878 Show fit	32.81	ENSRNOT00000009581	Slc3a1 NCBI RGD Ensembl Show fit	solute carrier family 3 member 1
chr3_-_8766433 Show fit	32.60	ENSRNOT00000021865	Kyat1 NCBI RGD Ensembl Show fit	kynurenine aminotransferase 1
chr2_-_53313884 Show fit	32.20	ENSRNOT00000046951	Ghr NCBI RGD Ensembl Show fit	growth hormone receptor
chr3_-_159775643 Show fit	31.61	ENSRNOT00000010939	Jph2 NCBI RGD Ensembl Show fit	junctophilin 2
chr5_+_159484370 Show fit	31.58	ENSRNOT00000010593	Sdhb NCBI RGD Ensembl Show fit	succinate dehydrogenase complex iron sulfur subunit B
chr11_-_77703255 Show fit	31.52	ENSRNOT00000083319	Cldn16 NCBI RGD Ensembl Show fit	claudin 16
chr5_-_126911520 Show fit	30.96	ENSRNOT00000091521	Dio1 NCBI RGD Ensembl Show fit	deiodinase, iodothyronine, type I
chr1_-_219144610 Show fit	30.79	ENSRNOT00000023526	Ndufs8 NCBI RGD Ensembl Show fit	NADH:ubiquinone oxidoreductase core subunit S8
chr3_-_80543031 Show fit	30.27	ENSRNOT00000022233	F2 NCBI RGD Ensembl Show fit	coagulation factor II
chr5_-_160179978 Show fit	29.64	ENSRNOT00000022820	Slc25a34 NCBI RGD Ensembl Show fit	solute carrier family 25, member 34
chr10_+_57278307 Show fit	29.36	ENSRNOT00000005612	Eno3 NCBI RGD Ensembl Show fit	enolase 3
chr8_-_77398156 Show fit	28.79	ENSRNOT00000091858 ENSRNOT00000085349 ENSRNOT00000082763	Lipc NCBI RGD Ensembl Show fit	lipase C, hepatic type
chr19_+_568287 Show fit	28.63	ENSRNOT00000016419	Cdh16 NCBI RGD Ensembl Show fit	cadherin 16
chr10_+_71159869 Show fit	28.20	ENSRNOT00000075977 ENSRNOT00000047427	Hnf1b NCBI RGD Ensembl Show fit	HNF1 homeobox B
chr13_-_56877611 Show fit	28.05	ENSRNOT00000079040 ENSRNOT00000017195	Cfhr1 NCBI RGD Ensembl Show fit	complement factor H-related 1
chr19_-_10596851 Show fit	27.73	ENSRNOT00000021716	Coq9 NCBI RGD Ensembl Show fit	coenzyme Q9
chr16_-_10941414 Show fit	27.41	ENSRNOT00000086627 ENSRNOT00000085414 ENSRNOT00000081631 ENSRNOT00000087521 ENSRNOT00000083623	Ldb3 NCBI RGD Ensembl Show fit	LIM domain binding 3
chr9_+_95256627 Show fit	27.23	ENSRNOT00000025291	Ugt1a5 NCBI RGD Ensembl Show fit	UDP glucuronosyltransferase family 1 member A5
chr6_+_23337571 Show fit	26.75	ENSRNOT00000011832	RGD1304963 NCBI RGD Ensembl Show fit	similar to hypothetical protein MGC38716
chr13_+_56598957 Show fit	26.69	ENSRNOT00000016944 ENSRNOT00000080335 ENSRNOT00000089913	F13b NCBI RGD Ensembl Show fit	coagulation factor XIII B chain
chr14_-_83741969 Show fit	26.56	ENSRNOT00000026293	Inpp5j NCBI RGD Ensembl Show fit	inositol polyphosphate-5-phosphatase J
chr15_-_27819376 Show fit	26.13	ENSRNOT00000067400	A930018M24Rik NCBI RGD Ensembl Show fit	RIKEN cDNA A930018M24 gene
chr10_+_11240138 Show fit	25.97	ENSRNOT00000048687	Srl NCBI RGD Ensembl Show fit	sarcalumenin
chr5_-_101138427 Show fit	25.85	ENSRNOT00000058615	Frem1 NCBI RGD Ensembl Show fit	Fras1 related extracellular matrix 1
chr18_+_63016761 Show fit	25.67	ENSRNOT00000081432	Impa2 NCBI RGD Ensembl Show fit	inositol monophosphatase 2
chr8_-_50526843 Show fit	25.40	ENSRNOT00000092188	AABR07070085.1 NCBI RGD Ensembl Show fit
chr6_-_7058314 Show fit	25.38	ENSRNOT00000045996	Haao NCBI RGD Ensembl Show fit	3-hydroxyanthranilate 3,4-dioxygenase
chr1_+_263554453 Show fit	25.24	ENSRNOT00000070861	Abcc2 NCBI RGD Ensembl Show fit	ATP binding cassette subfamily C member 2
chr1_-_224533219 Show fit	24.99	ENSRNOT00000051289	Ust5r NCBI RGD Ensembl Show fit	integral membrane transport protein UST5r
chr3_+_55910177 Show fit	24.78	ENSRNOT00000009969	Klhl41 NCBI RGD Ensembl Show fit	kelch-like family member 41
chr18_+_74156553 Show fit	24.67	ENSRNOT00000022892	Atp5a1 NCBI RGD Ensembl Show fit	ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
chr4_-_148845267 Show fit	24.61	ENSRNOT00000037397	Tmem72 NCBI RGD Ensembl Show fit	transmembrane protein 72
chr12_-_48218955 Show fit	24.40	ENSRNOT00000067975 ENSRNOT00000080557 ENSRNOT00000000821	Acacb NCBI RGD Ensembl Show fit	acetyl-CoA carboxylase beta
chr14_+_22937421 Show fit	24.32	ENSRNOT00000065079	RGD1559459 NCBI RGD Ensembl Show fit	similar to Expressed sequence AI788959
chr10_-_38782419 Show fit	23.92	ENSRNOT00000073964	Uqcrq NCBI RGD Ensembl Show fit	ubiquinol-cytochrome c reductase, complex III subunit VII
chr1_-_224389389 Show fit	23.50	ENSRNOT00000077408 ENSRNOT00000050010	UST4r NCBI RGD Ensembl Show fit	integral membrane transport protein UST4r
chr14_+_22517774 Show fit	23.45	ENSRNOT00000047655	Ugt2b37 NCBI RGD Ensembl Show fit	UDP-glucuronosyltransferase 2 family, member 37
chr11_-_32088002 Show fit	23.33	ENSRNOT00000002732	Atp5o NCBI RGD Ensembl Show fit	ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit
chr1_-_183763664 Show fit	23.31	ENSRNOT00000044231	LOC691427 NCBI RGD Ensembl Show fit	similar to 6.8 kDa mitochondrial proteolipid
chr7_-_118108864 Show fit	23.12	ENSRNOT00000006184	Mb NCBI RGD Ensembl Show fit	myoglobin
chr10_-_104748003 Show fit	22.55	ENSRNOT00000042372 ENSRNOT00000046754	Acox1 NCBI RGD Ensembl Show fit	acyl-CoA oxidase 1
chr10_+_37724915 Show fit	22.36	ENSRNOT00000008477	Vdac1 NCBI RGD Ensembl Show fit	voltage-dependent anion channel 1
chr1_-_89488223 Show fit	22.30	ENSRNOT00000028624	Fxyd1 NCBI RGD Ensembl Show fit	FXYD domain-containing ion transport regulator 1
chr13_-_93677377 Show fit	22.30	ENSRNOT00000004917	Fh NCBI RGD Ensembl Show fit	fumarate hydratase
chr2_-_119140110 Show fit	22.24	ENSRNOT00000058810	AABR07009978.1 NCBI RGD Ensembl Show fit
chr5_-_134927235 Show fit	22.17	ENSRNOT00000016751	Uqcrh NCBI RGD Ensembl Show fit	ubiquinol-cytochrome c reductase hinge protein
chr9_-_9985630 Show fit	22.12	ENSRNOT00000071780	Crb3 NCBI RGD Ensembl Show fit	crumbs 3, cell polarity complex component
chr13_-_56763981 Show fit	22.08	ENSRNOT00000087916	LOC100361907 NCBI RGD Ensembl Show fit	complement factor H-related protein B
chr10_-_38774449 Show fit	21.52	ENSRNOT00000049820	Leap2 NCBI RGD Ensembl Show fit	liver-expressed antimicrobial peptide 2
chr14_-_91996774 Show fit	21.51	ENSRNOT00000005851	Ddc NCBI RGD Ensembl Show fit	dopa decarboxylase
chr12_+_9446940 Show fit	21.41	ENSRNOT00000074791	Urad NCBI RGD Ensembl Show fit	ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase
chr5_+_159967839 Show fit	21.05	ENSRNOT00000051317	Hspb7 NCBI RGD Ensembl Show fit	heat shock protein family B (small) member 7
chr12_+_45905371 Show fit	20.91	ENSRNOT00000039275	Hspb8 NCBI RGD Ensembl Show fit	heat shock protein family B (small) member 8
chr15_+_57290849 Show fit	20.85	ENSRNOT00000014909	Cpb2 NCBI RGD Ensembl Show fit	carboxypeptidase B2
chr2_+_235738416 Show fit	20.68	ENSRNOT00000074209	Etnppl NCBI RGD Ensembl Show fit	ethanolamine-phosphate phospho-lyase
chr10_-_15235740 Show fit	20.60	ENSRNOT00000027170	Mcrip2 NCBI RGD Ensembl Show fit	MAPK regulated co-repressor interacting protein 2
chr8_-_23099042 Show fit	20.49	ENSRNOT00000019115	Ecsit NCBI RGD Ensembl Show fit	ECSIT signalling integrator
chr15_+_61069581 Show fit	20.49	ENSRNOT00000084333	Vwa8 NCBI RGD Ensembl Show fit	von Willebrand factor A domain containing 8
chr9_+_47536824 Show fit	20.32	ENSRNOT00000049349	Tmem182 NCBI RGD Ensembl Show fit	transmembrane protein 182
chr19_+_54245950 Show fit	20.31	ENSRNOT00000024033	Cox4i1 NCBI RGD Ensembl Show fit	cytochrome c oxidase subunit 4i1
chr5_+_160306727 Show fit	20.22	ENSRNOT00000016648	Agmat NCBI RGD Ensembl Show fit	agmatinase
chr1_+_224824799 Show fit	19.98	ENSRNOT00000024757	Slc22a6 NCBI RGD Ensembl Show fit	solute carrier family 22 member 6
chr5_+_90338795 Show fit	19.90	ENSRNOT00000077864 ENSRNOT00000058882	LOC298139 NCBI RGD Ensembl Show fit	similar to RIKEN cDNA 2310003M01
chr20_-_33323367 Show fit	19.76	ENSRNOT00000080444	Ros1 NCBI RGD Ensembl Show fit	ROS proto-oncogene 1 , receptor tyrosine kinase
chr3_-_172566010 Show fit	19.72	ENSRNOT00000071913	Atp5e NCBI RGD Ensembl Show fit	ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit
chr2_+_198965685 Show fit	19.54	ENSRNOT00000000107 ENSRNOT00000091578	Pdzk1 NCBI RGD Ensembl Show fit	PDZ domain containing 1
chr17_-_80807181 Show fit	19.49	ENSRNOT00000040052 ENSRNOT00000090064	Cubn NCBI RGD Ensembl Show fit	cubilin
chr13_-_82758004 Show fit	19.42	ENSRNOT00000003932	Atp1b1 NCBI RGD Ensembl Show fit	ATPase Na+/K+ transporting subunit beta 1
chr2_-_14701903 Show fit	19.26	ENSRNOT00000051895	Cox7c NCBI RGD Ensembl Show fit	cytochrome c oxidase subunit 7C
chr1_+_101884019 Show fit	19.25	ENSRNOT00000028650	Tmem143 NCBI RGD Ensembl Show fit	transmembrane protein 143
chr14_+_22142364 Show fit	19.20	ENSRNOT00000002699	Sult1b1 NCBI RGD Ensembl Show fit	sulfotransferase family 1B member 1
chr7_+_11490852 Show fit	19.15	ENSRNOT00000044484	Creb3l3 NCBI RGD Ensembl Show fit	cAMP responsive element binding protein 3-like 3
chr1_+_107344904 Show fit	18.98	ENSRNOT00000082582	Gas2 NCBI RGD Ensembl Show fit	growth arrest-specific 2
chr1_+_107262659 Show fit	18.90	ENSRNOT00000022499	Gas2 NCBI RGD Ensembl Show fit	growth arrest-specific 2
chr1_+_31264755 Show fit	18.85	ENSRNOT00000028988	LOC679739 NCBI RGD Ensembl Show fit	NADH dehydrogenase (ubiquinone) Fe-S protein 6
chr7_+_2504695 Show fit	18.75	ENSRNOT00000003965	Atp5b NCBI RGD Ensembl Show fit	ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide
chr9_+_17340341 Show fit	18.68	ENSRNOT00000026637 ENSRNOT00000026559 ENSRNOT00000042790 ENSRNOT00000044163 ENSRNOT00000083811	Vegfa NCBI RGD Ensembl Show fit	vascular endothelial growth factor A
chrX_+_143097525 Show fit	18.62	ENSRNOT00000004559	F9 NCBI RGD Ensembl Show fit	coagulation factor IX
chr11_+_80736576 Show fit	18.22	ENSRNOT00000047678	Masp1 NCBI RGD Ensembl Show fit	mannan-binding lectin serine peptidase 1
chr2_+_182006242 Show fit	18.13	ENSRNOT00000064091	Fga NCBI RGD Ensembl Show fit	fibrinogen alpha chain
chr1_+_213676954 Show fit	17.93	ENSRNOT00000050551	Nlrp6 NCBI RGD Ensembl Show fit	NLR family, pyrin domain containing 6
chr1_-_263269762 Show fit	17.74	ENSRNOT00000022309	Got1 NCBI RGD Ensembl Show fit	glutamic-oxaloacetic transaminase 1
chr1_-_222350173 Show fit	17.56	ENSRNOT00000030625	Flrt1 NCBI RGD Ensembl Show fit	fibronectin leucine rich transmembrane protein 1
chr14_-_84937725 Show fit	17.43	ENSRNOT00000083839	Uqcr10 NCBI RGD Ensembl Show fit	ubiquinol-cytochrome c reductase, complex III subunit X
chr8_-_78233430 Show fit	17.36	ENSRNOT00000083220	Cgnl1 NCBI RGD Ensembl Show fit	cingulin-like 1
chrX_+_110818716 Show fit	17.24	ENSRNOT00000086308	Rnf128 NCBI RGD Ensembl Show fit	ring finger protein 128, E3 ubiquitin protein ligase
chr9_+_95274707 Show fit	17.21	ENSRNOT00000045163	Ugt1a5 NCBI RGD Ensembl Show fit	UDP glucuronosyltransferase family 1 member A5
chr5_-_19368431 Show fit	17.18	ENSRNOT00000012819	Cyp7a1 NCBI RGD Ensembl Show fit	cytochrome P450, family 7, subfamily a, polypeptide 1
chr2_+_187347602 Show fit	17.16	ENSRNOT00000025384	Nes NCBI RGD Ensembl Show fit	nestin
chr1_-_214263581 Show fit	17.09	ENSRNOT00000044238	Cdhr5 NCBI RGD Ensembl Show fit	cadherin-related family member 5
chr12_+_10636275 Show fit	17.09	ENSRNOT00000001285	Cyp3a18 NCBI RGD Ensembl Show fit	cytochrome P450, family 3, subfamily a, polypeptide 18
chr5_-_126080698 Show fit	16.89	ENSRNOT00000008739	Bsnd NCBI RGD Ensembl Show fit	barttin CLCNK type accessory beta subunit
chr20_-_45126062 Show fit	16.89	ENSRNOT00000000720	RGD1310495 NCBI RGD Ensembl Show fit	similar to KIAA1919 protein
chr7_-_74735650 Show fit	16.88	ENSRNOT00000014407	Cox6c NCBI RGD Ensembl Show fit	cytochrome c oxidase subunit 6C
chr11_-_71750014 Show fit	16.72	ENSRNOT00000072227	LOC100911042 NCBI RGD Ensembl Show fit	uncharacterized LOC100911042
chr7_+_38742051 Show fit	16.66	ENSRNOT00000006070	Dcn NCBI RGD Ensembl Show fit	decorin
chr9_+_61692154 Show fit	16.62	ENSRNOT00000082300	Hspe1 NCBI RGD Ensembl Show fit	heat shock protein family E member 1
chr9_+_43259709 Show fit	16.56	ENSRNOT00000022487	Cox5b NCBI RGD Ensembl Show fit	cytochrome c oxidase subunit 5B
chr8_-_50539331 Show fit	16.55	ENSRNOT00000088997	AABR07073400.1 NCBI RGD Ensembl Show fit
chr2_-_28750237 Show fit	16.54	ENSRNOT00000020879	Tmem174 NCBI RGD Ensembl Show fit	transmembrane protein 174
chr12_+_47407811 Show fit	16.30	ENSRNOT00000001565	Hnf1a NCBI RGD Ensembl Show fit	HNF1 homeobox A
chr7_+_117409576 Show fit	16.27	ENSRNOT00000017067	Cyc1 NCBI RGD Ensembl Show fit	cytochrome c-1
chr5_+_147185474 Show fit	16.27	ENSRNOT00000000134	Ak2 NCBI RGD Ensembl Show fit	adenylate kinase 2
chr5_+_78222504 Show fit	16.23	ENSRNOT00000019544	Slc31a1 NCBI RGD Ensembl Show fit	solute carrier family 31 member 1
chr5_+_126334803 Show fit	16.18	ENSRNOT00000010288	Fam151a NCBI RGD Ensembl Show fit	family with sequence similarity 151, member A
chr8_+_71167305 Show fit	15.93	ENSRNOT00000021337	Rbpms2 NCBI RGD Ensembl Show fit	RNA binding protein with multiple splicing 2
chr4_-_15505362 Show fit	15.89	ENSRNOT00000009763	Hgf NCBI RGD Ensembl Show fit	hepatocyte growth factor
chr7_+_12840938 Show fit	15.73	ENSRNOT00000039232	Polrmt NCBI RGD Ensembl Show fit	RNA polymerase mitochondrial
chr1_-_263762785 Show fit	15.66	ENSRNOT00000018221	Cpn1 NCBI RGD Ensembl Show fit	carboxypeptidase N subunit 1
chr12_+_39553903 Show fit	15.55	ENSRNOT00000001738	Atp2a2 NCBI RGD Ensembl Show fit	ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2
chr3_+_58632476 Show fit	15.40	ENSRNOT00000010630	Rapgef4 NCBI RGD Ensembl Show fit	Rap guanine nucleotide exchange factor 4
chr17_-_10001901 Show fit	15.40	ENSRNOT00000082836	Fgfr4 NCBI RGD Ensembl Show fit	fibroblast growth factor receptor 4
chr13_-_56958549 Show fit	15.25	ENSRNOT00000017293 ENSRNOT00000083912	RGD1564614 NCBI RGD Ensembl Show fit	similar to complement factor H-related protein
chr2_+_56426367 Show fit	15.17	ENSRNOT00000016036	Lifr NCBI RGD Ensembl Show fit	leukemia inhibitory factor receptor alpha
chr1_-_277181345 Show fit	15.15	ENSRNOT00000038017 ENSRNOT00000038038	Nrap NCBI RGD Ensembl Show fit	nebulin-related anchoring protein
chr3_-_127500709 Show fit	14.97	ENSRNOT00000006330	Hao1 NCBI RGD Ensembl Show fit	hydroxyacid oxidase 1
chr13_-_89518939 Show fit	14.96	ENSRNOT00000004228	Sdhc NCBI RGD Ensembl Show fit	succinate dehydrogenase complex subunit C
chr8_+_112594691 Show fit	14.80	ENSRNOT00000038383 ENSRNOT00000081281	Acad11 NCBI RGD Ensembl Show fit	acyl-CoA dehydrogenase family, member 11
chr5_+_173640780 Show fit	14.76	ENSRNOT00000027476	Perm1 NCBI RGD Ensembl Show fit	PPARGC1 and ESRR induced regulator, muscle 1
chr7_-_80796670 Show fit	14.65	ENSRNOT00000010539	Abra NCBI RGD Ensembl Show fit	actin-binding Rho activating protein
chr18_-_28425944 Show fit	14.60	ENSRNOT00000084372	Slc23a1 NCBI RGD Ensembl Show fit	solute carrier family 23 member 1
chr12_+_47254484 Show fit	14.55	ENSRNOT00000001556	Acads NCBI RGD Ensembl Show fit	acyl-CoA dehydrogenase, C-2 to C-3 short chain
chr3_+_61613774 Show fit	14.54	ENSRNOT00000002148	Hoxd10 NCBI RGD Ensembl Show fit	homeo box D10
chr1_+_213686046 Show fit	14.18	ENSRNOT00000019808	LOC108348167 NCBI RGD Ensembl Show fit	NACHT, LRR and PYD domains-containing protein 6-like
chr7_+_53630621 Show fit	14.12	ENSRNOT00000067011 ENSRNOT00000080598	Csrp2 NCBI RGD Ensembl Show fit	cysteine and glycine-rich protein 2
chr1_+_101884276 Show fit	14.10	ENSRNOT00000082917	Tmem143 NCBI RGD Ensembl Show fit	transmembrane protein 143
chr8_-_130429132 Show fit	14.05	ENSRNOT00000026261	Hhatl NCBI RGD Ensembl Show fit	hedgehog acyltransferase-like
chr4_-_38240848 Show fit	13.89	ENSRNOT00000007567	Ndufa4 NCBI RGD Ensembl Show fit	NADH:ubiquinone oxidoreductase subunit A4
chr10_+_56662561 Show fit	13.83	ENSRNOT00000025254	Asgr1 NCBI RGD Ensembl Show fit	asialoglycoprotein receptor 1
chr4_-_82215022 Show fit	13.83	ENSRNOT00000010256	Hoxa11 NCBI RGD Ensembl Show fit	homeobox A11
chr2_+_204512302 Show fit	13.81	ENSRNOT00000021846	Casq2 NCBI RGD Ensembl Show fit	calsequestrin 2
chr7_+_35125424 Show fit	13.76	ENSRNOT00000085978 ENSRNOT00000010117	Ndufa12 NCBI RGD Ensembl Show fit	NADH:ubiquinone oxidoreductase subunit A12
chr2_+_263895241 Show fit	13.65	ENSRNOT00000014126 ENSRNOT00000014034	Ptger3 NCBI RGD Ensembl Show fit	prostaglandin E receptor 3
chr8_-_55037604 Show fit	13.55	ENSRNOT00000059169	Sdhd NCBI RGD Ensembl Show fit	succinate dehydrogenase complex subunit D
chr11_-_87924816 Show fit	13.54	ENSRNOT00000031819	Serpind1 NCBI RGD Ensembl Show fit	serpin family D member 1
chr1_-_222178725 Show fit	13.36	ENSRNOT00000028697	Esrra NCBI RGD Ensembl Show fit	estrogen related receptor, alpha
chr2_+_235264219 Show fit	13.22	ENSRNOT00000086245	Cfi NCBI RGD Ensembl Show fit	complement factor I
chr1_-_143535583 Show fit	13.15	ENSRNOT00000087785	Homer2 NCBI RGD Ensembl Show fit	homer scaffolding protein 2
chr10_+_56662242 Show fit	13.07	ENSRNOT00000086919	Asgr1 NCBI RGD Ensembl Show fit	asialoglycoprotein receptor 1
chr18_-_55891710 Show fit	13.03	ENSRNOT00000064686	Synpo NCBI RGD Ensembl Show fit	synaptopodin
chr8_-_47339343 Show fit	13.02	ENSRNOT00000081007	Arhgef12 NCBI RGD Ensembl Show fit	Rho guanine nucleotide exchange factor 12
chr9_+_20213776 Show fit	13.00	ENSRNOT00000071439	LOC100911515 NCBI RGD Ensembl Show fit	triosephosphate isomerase-like
chr4_-_157331905 Show fit	12.64	ENSRNOT00000020647	Tpi1 NCBI RGD Ensembl Show fit	triosephosphate isomerase 1
chr11_-_38088753 Show fit	12.54	ENSRNOT00000002713	Tmprss2 NCBI RGD Ensembl Show fit	transmembrane protease, serine 2
chr10_-_18506337 Show fit	12.48	ENSRNOT00000043036	Gabrp NCBI RGD Ensembl Show fit	gamma-aminobutyric acid type A receptor pi subunit
chr3_+_151126591 Show fit	12.44	ENSRNOT00000025859	Myh7b NCBI RGD Ensembl Show fit	myosin heavy chain 7B
chr1_+_87009730 Show fit	12.37	ENSRNOT00000027537	Ech1 NCBI RGD Ensembl Show fit	enoyl-CoA hydratase 1
chr10_-_50574539 Show fit	12.35	ENSRNOT00000034261	Cox10 NCBI RGD Ensembl Show fit	COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor
chr2_+_93669765 Show fit	12.33	ENSRNOT00000045438	Slc10a5 NCBI RGD Ensembl Show fit	solute carrier family 10, member 5
chr7_-_44771458 Show fit	12.31	ENSRNOT00000006007	Alx1 NCBI RGD Ensembl Show fit	ALX homeobox 1
chr7_+_121311024 Show fit	12.27	ENSRNOT00000092260 ENSRNOT00000023066 ENSRNOT00000081377	Syngr1 NCBI RGD Ensembl Show fit	synaptogyrin 1
chr14_-_106234247 Show fit	12.25	ENSRNOT00000081245	Ugp2 NCBI RGD Ensembl Show fit	UDP-glucose pyrophosphorylase 2
chrX_+_77263359 Show fit	12.14	ENSRNOT00000077604	Pgk1 NCBI RGD Ensembl Show fit	phosphoglycerate kinase 1
chrX_-_135342996 Show fit	12.13	ENSRNOT00000084848 ENSRNOT00000008503	Aifm1 NCBI RGD Ensembl Show fit	apoptosis inducing factor, mitochondria associated 1
chr20_+_28989491 Show fit	12.13	ENSRNOT00000074524	Pla2g12b NCBI RGD Ensembl Show fit	phospholipase A2, group XIIB
chr1_+_41192824 Show fit	12.09	ENSRNOT00000082133	Esr1 NCBI RGD Ensembl Show fit	estrogen receptor 1
chr1_-_80617057 Show fit	12.06	ENSRNOT00000080453	Apoe NCBI RGD Ensembl Show fit	apolipoprotein E
chr6_+_27589657 Show fit	11.91	ENSRNOT00000038649	Hadha NCBI RGD Ensembl Show fit	hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
chr5_+_137357674 Show fit	11.91	ENSRNOT00000092813	RGD1305347 NCBI RGD Ensembl Show fit	similar to RIKEN cDNA 2610528J11
chr2_+_256609787 Show fit	11.85	ENSRNOT00000047564 ENSRNOT00000088437	Adgrl4 NCBI RGD Ensembl Show fit	adhesion G protein-coupled receptor L4
chr8_+_117679278 Show fit	11.85	ENSRNOT00000042114	Uqcrc1 NCBI RGD Ensembl Show fit	ubiquinol-cytochrome c reductase core protein I
chr6_+_107460668 Show fit	11.83	ENSRNOT00000013515	Acot2 NCBI RGD Ensembl Show fit	acyl-CoA thioesterase 2
chr4_-_89281222 Show fit	11.73	ENSRNOT00000010898	Fam13a NCBI RGD Ensembl Show fit	family with sequence similarity 13, member A
chr1_-_49844547 Show fit	11.65	ENSRNOT00000086127 ENSRNOT00000077423 ENSRNOT00000089439 ENSRNOT00000090521	AABR07001519.1 NCBI RGD Ensembl Show fit
chr8_+_59164572 Show fit	11.63	ENSRNOT00000015102	Idh3a NCBI RGD Ensembl Show fit	isocitrate dehydrogenase 3 (NAD+) alpha
chr9_-_69953182 Show fit	11.58	ENSRNOT00000015852	Ndufs1 NCBI RGD Ensembl Show fit	NADH dehydrogenase (ubiquinone) Fe-S protein 1
chrX_+_106774980 Show fit	11.55	ENSRNOT00000046091	Tceal7 NCBI RGD Ensembl Show fit	transcription elongation factor A like 7
chr13_+_75175254 Show fit	11.54	ENSRNOT00000044008	Sec16b NCBI RGD Ensembl Show fit	SEC16 homolog B, endoplasmic reticulum export factor
chr7_-_31824064 Show fit	11.47	ENSRNOT00000011494 ENSRNOT00000080824	Slc25a3 NCBI RGD Ensembl Show fit	solute carrier family 25 member 3
chr4_+_82214342 Show fit	11.47	ENSRNOT00000066360	Hoxa11-as NCBI RGD Ensembl Show fit	homeobox A11, opposite strand
chr1_+_242572533 Show fit	11.33	ENSRNOT00000035123	Tmem252 NCBI RGD Ensembl Show fit	transmembrane protein 252
chr14_-_8432195 Show fit	11.32	ENSRNOT00000089800	Arhgap24 NCBI RGD Ensembl Show fit	Rho GTPase activating protein 24
chr17_+_32973695 Show fit	11.26	ENSRNOT00000065674	RGD1565323 NCBI RGD Ensembl Show fit	similar to OTTMUSP00000000621
chr1_+_72882806 Show fit	10.94	ENSRNOT00000024640	Tnni3 NCBI RGD Ensembl Show fit	troponin I3, cardiac type
chr14_+_26662965 Show fit	10.93	ENSRNOT00000002621	Tecrl NCBI RGD Ensembl Show fit	trans-2,3-enoyl-CoA reductase-like
chr4_+_82300778 Show fit	10.85	ENSRNOT00000075254	Hoxa11-as NCBI RGD Ensembl Show fit	homeobox A11, opposite strand
chr9_+_64745051 Show fit	10.85	ENSRNOT00000021527	Spats2l NCBI RGD Ensembl Show fit	spermatogenesis associated, serine-rich 2-like
chr1_-_253186695 Show fit	10.84	ENSRNOT00000080928	AC096809.1 NCBI RGD Ensembl Show fit
chr4_+_51614676 Show fit	10.84	ENSRNOT00000060494	Asb15 NCBI RGD Ensembl Show fit	ankyrin repeat and SOCS box containing 15
chr3_+_121490812 Show fit	10.78	ENSRNOT00000023913	AABR07053707.1 NCBI RGD Ensembl Show fit

Network of associatons between targets according to the STRING database.

First level regulatory network of Nr2f1_Nr4a1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
27.7	83.1	GO:0010903	negative regulation of very-low-density lipoprotein particle remodeling(GO:0010903) regulation of high-density lipoprotein particle clearance(GO:0010982)
15.8	47.5	GO:0006121	mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
15.8	63.3	GO:2001295	malonyl-CoA biosynthetic process(GO:2001295)
15.6	46.9	GO:0010796	regulation of multivesicular body size(GO:0010796)
15.4	46.2	GO:2001137	actin filament uncapping(GO:0051695) phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097) positive regulation of endocytic recycling(GO:2001137)
15.2	45.7	GO:0006579	amino-acid betaine catabolic process(GO:0006579)
15.0	15.0	GO:0009441	glycolate metabolic process(GO:0009441)
14.0	56.2	GO:0042776	mitochondrial ATP synthesis coupled proton transport(GO:0042776)
13.3	40.0	GO:0006106	fumarate metabolic process(GO:0006106)
12.9	38.7	GO:0038163	thrombopoietin-mediated signaling pathway(GO:0038163)
11.5	34.5	GO:0006114	glycerol biosynthetic process(GO:0006114)
11.1	44.5	GO:0035565	regulation of pronephros size(GO:0035565)
10.9	43.8	GO:0030240	skeletal muscle thin filament assembly(GO:0030240)
10.1	30.3	GO:1905225	response to thyrotropin-releasing hormone(GO:1905225)
8.7	26.0	GO:0014873	response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
8.5	25.4	GO:0019805	quinolinate biosynthetic process(GO:0019805)
8.4	33.6	GO:0050787	detoxification of mercury ion(GO:0050787)
8.3	41.7	GO:1903278	positive regulation of sodium ion export(GO:1903275) positive regulation of sodium ion export from cell(GO:1903278)
8.1	32.6	GO:0097052	L-kynurenine metabolic process(GO:0097052)
8.0	24.0	GO:0038190	neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190)
8.0	23.9	GO:0021539	subthalamus development(GO:0021539)
7.8	23.3	GO:1903116	positive regulation of actin filament-based movement(GO:1903116)
7.7	23.1	GO:0031444	slow-twitch skeletal muscle fiber contraction(GO:0031444)
7.7	77.0	GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
7.7	23.0	GO:0010034	response to acetate(GO:0010034)
7.5	22.5	GO:0033540	fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
7.0	20.9	GO:0003331	regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
6.5	52.1	GO:0034196	acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
6.0	47.9	GO:0019388	galactose catabolic process(GO:0019388)
6.0	17.9	GO:0042412	taurine biosynthetic process(GO:0042412)
5.7	45.3	GO:0033133	positive regulation of glucokinase activity(GO:0033133)
5.6	5.6	GO:0044330	canonical Wnt signaling pathway involved in positive regulation of wound healing(GO:0044330)
5.4	21.5	GO:0052314	phytoalexin metabolic process(GO:0052314)
5.2	15.5	GO:1903233	positive regulation of endoplasmic reticulum calcium ion concentration(GO:0032470) regulation of calcium ion-dependent exocytosis of neurotransmitter(GO:1903233) calcium ion import into sarcoplasmic reticulum(GO:1990036)
5.1	15.4	GO:1904457	positive regulation of neuronal action potential(GO:1904457)
5.0	123.9	GO:0015986	energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
4.9	44.4	GO:0052697	xenobiotic glucuronidation(GO:0052697)
4.9	14.7	GO:0010133	proline catabolic process to glutamate(GO:0010133)
4.9	19.5	GO:0015879	carnitine transport(GO:0015879)
4.9	14.6	GO:0015882	L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
4.8	33.5	GO:0060316	positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
4.4	39.2	GO:0072338	creatinine metabolic process(GO:0046449) cellular lactam metabolic process(GO:0072338)
4.3	17.2	GO:0045105	intermediate filament polymerization or depolymerization(GO:0045105)
4.1	12.2	GO:0006011	UDP-glucose metabolic process(GO:0006011) glucose 1-phosphate metabolic process(GO:0019255)
4.1	44.8	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
4.1	16.3	GO:0006172	ADP biosynthetic process(GO:0006172)
4.1	16.2	GO:1902861	copper ion import across plasma membrane(GO:0098705) copper ion import into cell(GO:1902861)
4.0	20.2	GO:0008295	spermidine biosynthetic process(GO:0008295)
4.0	12.1	GO:1903002	regulation of lipid transport across blood brain barrier(GO:1903000) positive regulation of lipid transport across blood brain barrier(GO:1903002)
4.0	20.0	GO:0031427	response to methotrexate(GO:0031427)
4.0	8.0	GO:1903070	negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
4.0	15.9	GO:1902947	regulation of tau-protein kinase activity(GO:1902947)
3.9	31.6	GO:0006105	succinate metabolic process(GO:0006105)
3.9	19.5	GO:0015889	cobalamin transport(GO:0015889)
3.8	15.4	GO:0007037	vacuolar phosphate transport(GO:0007037) positive regulation of parathyroid hormone secretion(GO:2000830)
3.8	15.2	GO:0038165	oncostatin-M-mediated signaling pathway(GO:0038165) leukemia inhibitory factor signaling pathway(GO:0048861)
3.6	18.1	GO:0043152	induction of bacterial agglutination(GO:0043152)
3.5	14.1	GO:1903059	regulation of protein lipidation(GO:1903059)
3.4	17.1	GO:1904970	brush border assembly(GO:1904970)
3.4	34.0	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
3.3	26.8	GO:1903546	protein localization to photoreceptor outer segment(GO:1903546)
3.3	9.9	GO:0019747	regulation of isoprenoid metabolic process(GO:0019747)
3.3	19.8	GO:0010966	regulation of phosphate transport(GO:0010966)
3.3	13.0	GO:0098886	modification of dendritic spine(GO:0098886)
3.2	25.7	GO:0006021	inositol biosynthetic process(GO:0006021)
3.2	9.5	GO:0045041	protein import into mitochondrial intermembrane space(GO:0045041)
3.1	15.7	GO:0030070	insulin processing(GO:0030070)
3.0	12.1	GO:1990375	baculum development(GO:1990375)
2.9	8.6	GO:2000546	positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
2.8	13.8	GO:0071313	cellular response to caffeine(GO:0071313)
2.7	19.2	GO:0009812	flavonoid metabolic process(GO:0009812)
2.7	8.1	GO:0042822	pyridoxal phosphate metabolic process(GO:0042822)
2.7	21.3	GO:0035021	negative regulation of Rac protein signal transduction(GO:0035021)
2.7	8.0	GO:1902445	regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
2.6	10.4	GO:1902031	regulation of NADP metabolic process(GO:1902031)
2.6	7.8	GO:0000105	histidine biosynthetic process(GO:0000105)
2.5	12.6	GO:0019563	glycerol catabolic process(GO:0019563)
2.5	7.4	GO:0021627	muscle attachment(GO:0016203) olfactory nerve morphogenesis(GO:0021627) olfactory nerve structural organization(GO:0021629)
2.4	12.1	GO:1904045	cellular response to aldosterone(GO:1904045)
2.4	7.2	GO:1902037	negative regulation of hematopoietic stem cell differentiation(GO:1902037)
2.4	16.7	GO:1900747	negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
2.4	7.1	GO:0009249	protein lipoylation(GO:0009249)
2.3	23.5	GO:0015747	urate transport(GO:0015747)
2.3	41.3	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
2.3	6.8	GO:0042222	interleukin-1 biosynthetic process(GO:0042222)
2.3	31.5	GO:0070633	transepithelial transport(GO:0070633)
2.0	6.1	GO:0006543	glutamine catabolic process(GO:0006543)
2.0	26.3	GO:0006390	transcription from mitochondrial promoter(GO:0006390)
1.9	11.6	GO:0006102	isocitrate metabolic process(GO:0006102)
1.9	1.9	GO:0010841	positive regulation of circadian sleep/wake cycle, wakefulness(GO:0010841)
1.9	7.7	GO:0019072	viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
1.9	24.8	GO:2000291	regulation of myoblast proliferation(GO:2000291)
1.9	24.2	GO:0006851	mitochondrial calcium ion transport(GO:0006851)
1.8	7.3	GO:0046351	disaccharide biosynthetic process(GO:0046351)
1.8	21.8	GO:0035814	negative regulation of renal sodium excretion(GO:0035814)
1.8	3.6	GO:0046604	positive regulation of mitotic centrosome separation(GO:0046604)
1.8	21.2	GO:0070863	positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
1.7	3.5	GO:0060066	oviduct development(GO:0060066)
1.7	17.2	GO:0070857	regulation of bile acid biosynthetic process(GO:0070857)
1.7	27.5	GO:0006744	ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
1.7	11.8	GO:0042760	very long-chain fatty acid catabolic process(GO:0042760)
1.7	32.0	GO:0010257	NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
1.7	5.0	GO:2001205	negative regulation of osteoclast development(GO:2001205)
1.7	29.9	GO:0031115	negative regulation of microtubule polymerization(GO:0031115)
1.6	31.3	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
1.6	4.9	GO:0009644	response to high light intensity(GO:0009644)
1.6	22.8	GO:0060272	embryonic skeletal joint morphogenesis(GO:0060272)
1.6	6.5	GO:1903691	positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
1.6	12.5	GO:0006703	estrogen biosynthetic process(GO:0006703)
1.5	18.2	GO:0045916	negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
1.4	2.9	GO:0098923	retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543)
1.4	9.8	GO:0039536	negative regulation of RIG-I signaling pathway(GO:0039536)
1.4	7.0	GO:0061727	methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
1.4	4.1	GO:0051012	microtubule sliding(GO:0051012)
1.4	6.8	GO:0086048	membrane depolarization during Purkinje myocyte cell action potential(GO:0086047) membrane depolarization during bundle of His cell action potential(GO:0086048)
1.4	5.4	GO:1905233	carbohydrate export(GO:0033231) daunorubicin transport(GO:0043215) response to borneol(GO:1905230) cellular response to borneol(GO:1905231) response to codeine(GO:1905233) response to quercetin(GO:1905235) drug transport across blood-brain barrier(GO:1990962) establishment of blood-retinal barrier(GO:1990963)
1.4	4.1	GO:0071579	regulation of zinc ion transport(GO:0071579)
1.3	9.4	GO:0070508	sterol import(GO:0035376) cholesterol import(GO:0070508)
1.3	1.3	GO:1904054	regulation of cholangiocyte proliferation(GO:1904054) positive regulation of cholangiocyte proliferation(GO:1904056)
1.3	10.5	GO:0060613	fat pad development(GO:0060613)
1.3	6.5	GO:0000960	mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
1.3	16.8	GO:0051151	negative regulation of smooth muscle cell differentiation(GO:0051151)
1.3	19.2	GO:1990440	positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
1.3	3.8	GO:0017062	respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
1.2	3.7	GO:0090074	negative regulation of protein homodimerization activity(GO:0090074)
1.2	14.5	GO:0048934	peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
1.2	2.4	GO:0003130	BMP signaling pathway involved in heart induction(GO:0003130) endodermal-mesodermal cell signaling(GO:0003133) endodermal-mesodermal cell signaling involved in heart induction(GO:0003134)
1.2	26.0	GO:0097094	craniofacial suture morphogenesis(GO:0097094)
1.2	2.3	GO:0033552	response to vitamin B3(GO:0033552)
1.2	9.3	GO:0055089	fatty acid homeostasis(GO:0055089)
1.1	17.9	GO:0070255	regulation of mucus secretion(GO:0070255)
1.1	3.3	GO:0015680	intracellular copper ion transport(GO:0015680)
1.1	5.5	GO:0042264	peptidyl-aspartic acid hydroxylation(GO:0042264)
1.1	30.4	GO:0014002	astrocyte development(GO:0014002)
1.1	32.6	GO:0042773	ATP synthesis coupled electron transport(GO:0042773)
1.0	12.5	GO:0046598	positive regulation of viral entry into host cell(GO:0046598)
1.0	16.6	GO:0051085	chaperone mediated protein folding requiring cofactor(GO:0051085)
1.0	20.9	GO:0019682	pentose-phosphate shunt(GO:0006098) glyceraldehyde-3-phosphate metabolic process(GO:0019682)
1.0	10.9	GO:0010882	regulation of cardiac muscle contraction by calcium ion signaling(GO:0010882)
1.0	2.9	GO:0046078	dUMP metabolic process(GO:0046078)
1.0	18.3	GO:0031581	hemidesmosome assembly(GO:0031581)
0.9	4.7	GO:2000324	positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.9	3.8	GO:0016103	diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.9	14.8	GO:0014850	response to muscle activity(GO:0014850)
0.9	6.4	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.9	3.7	GO:0002084	protein depalmitoylation(GO:0002084)
0.9	2.7	GO:0072076	nephrogenic mesenchyme development(GO:0072076) pattern specification involved in metanephros development(GO:0072268)
0.9	12.4	GO:0008535	respiratory chain complex IV assembly(GO:0008535)
0.9	29.4	GO:0043403	skeletal muscle tissue regeneration(GO:0043403)
0.9	5.2	GO:0030046	parallel actin filament bundle assembly(GO:0030046)
0.8	4.2	GO:0045218	zonula adherens maintenance(GO:0045218)
0.8	12.5	GO:0010666	positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666)
0.8	2.5	GO:0032053	ciliary basal body organization(GO:0032053) positive regulation of protein localization to cilium(GO:1903566)
0.8	7.4	GO:0034975	protein folding in endoplasmic reticulum(GO:0034975)
0.8	2.4	GO:0034241	positive regulation of macrophage fusion(GO:0034241)
0.8	4.8	GO:0032914	positive regulation of transforming growth factor beta1 production(GO:0032914)
0.8	12.1	GO:0030150	protein import into mitochondrial matrix(GO:0030150)
0.8	8.0	GO:0051560	mitochondrial calcium ion homeostasis(GO:0051560)
0.8	5.6	GO:0044351	macropinocytosis(GO:0044351)
0.8	10.3	GO:0016188	synaptic vesicle maturation(GO:0016188)
0.8	11.4	GO:0006688	glycosphingolipid biosynthetic process(GO:0006688)
0.8	3.8	GO:0070125	mitochondrial translational elongation(GO:0070125)
0.7	3.7	GO:0009298	GDP-mannose biosynthetic process(GO:0009298)
0.7	13.1	GO:0035584	calcium-mediated signaling using intracellular calcium source(GO:0035584)
0.7	9.5	GO:0006086	acetyl-CoA biosynthetic process from pyruvate(GO:0006086)
0.7	12.3	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.7	4.2	GO:0070885	negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.7	9.2	GO:0034063	stress granule assembly(GO:0034063)
0.7	33.9	GO:0042446	hormone biosynthetic process(GO:0042446)
0.7	9.9	GO:0090140	regulation of mitochondrial fission(GO:0090140)
0.7	13.2	GO:0006958	complement activation, classical pathway(GO:0006958)
0.6	6.4	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.6	7.0	GO:0006099	tricarboxylic acid cycle(GO:0006099)
0.6	2.5	GO:0018214	peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.6	8.6	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.6	11.5	GO:0035435	phosphate ion transmembrane transport(GO:0035435)
0.6	23.7	GO:0032543	mitochondrial translation(GO:0032543)
0.6	1.7	GO:0046947	hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.5	2.1	GO:0043951	negative regulation of cAMP-mediated signaling(GO:0043951)
0.5	13.4	GO:1900078	positive regulation of cellular response to insulin stimulus(GO:1900078)
0.5	12.1	GO:0070328	acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
0.5	4.5	GO:0090091	positive regulation of extracellular matrix disassembly(GO:0090091)
0.5	2.9	GO:0070164	negative regulation of adiponectin secretion(GO:0070164)
0.5	2.4	GO:1902162	regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162)
0.5	6.2	GO:0071340	skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.5	3.8	GO:0071318	cellular response to ATP(GO:0071318)
0.5	2.4	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.5	15.0	GO:0035025	positive regulation of Rho protein signal transduction(GO:0035025)
0.5	12.1	GO:0031639	plasminogen activation(GO:0031639)
0.5	3.2	GO:0035879	plasma membrane lactate transport(GO:0035879)
0.5	0.9	GO:0032252	regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) secretory granule localization(GO:0032252)
0.4	1.3	GO:2000721	positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.4	2.6	GO:2000973	regulation of pro-B cell differentiation(GO:2000973)
0.4	3.8	GO:0007000	nucleolus organization(GO:0007000)
0.4	2.9	GO:0046133	pyrimidine ribonucleoside catabolic process(GO:0046133)
0.4	2.0	GO:0018344	protein geranylgeranylation(GO:0018344)
0.4	18.9	GO:0006635	fatty acid beta-oxidation(GO:0006635)
0.4	1.2	GO:2000054	negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.4	12.3	GO:0010718	positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.4	5.9	GO:0090201	negative regulation of release of cytochrome c from mitochondria(GO:0090201)
0.4	17.6	GO:0046426	negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.4	5.0	GO:0015937	coenzyme A biosynthetic process(GO:0015937)
0.4	5.7	GO:0043950	positive regulation of cAMP-mediated signaling(GO:0043950)
0.4	10.5	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.4	1.1	GO:0061589	calcium activated phosphatidylserine scrambling(GO:0061589)
0.4	4.1	GO:0044331	cell-cell adhesion mediated by cadherin(GO:0044331)
0.4	1.1	GO:0043328	protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.4	5.1	GO:0001967	suckling behavior(GO:0001967)
0.4	1.1	GO:0032218	riboflavin transport(GO:0032218)
0.4	0.7	GO:0097018	positive regulation of glomerular filtration(GO:0003104) renal albumin absorption(GO:0097018) regulation of renal albumin absorption(GO:2000532)
0.3	5.9	GO:0006491	N-glycan processing(GO:0006491)
0.3	52.8	GO:0007596	blood coagulation(GO:0007596)
0.3	5.0	GO:0006646	phosphatidylethanolamine biosynthetic process(GO:0006646)
0.3	1.6	GO:0070309	lens fiber cell morphogenesis(GO:0070309)
0.3	3.5	GO:0031340	positive regulation of vesicle fusion(GO:0031340)
0.3	2.5	GO:0033623	regulation of integrin activation(GO:0033623)
0.3	2.2	GO:0097428	protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.3	1.2	GO:1904431	positive regulation of t-circle formation(GO:1904431)
0.3	0.9	GO:0044376	RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.3	11.3	GO:0071806	protein transmembrane transport(GO:0071806)
0.3	1.2	GO:0007182	common-partner SMAD protein phosphorylation(GO:0007182)
0.3	2.9	GO:0061051	positive regulation of cell growth involved in cardiac muscle cell development(GO:0061051)
0.3	3.7	GO:0031424	keratinization(GO:0031424)
0.3	6.2	GO:0015721	bile acid and bile salt transport(GO:0015721)
0.3	1.7	GO:2000074	regulation of type B pancreatic cell development(GO:2000074) negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.3	3.8	GO:0007097	nuclear migration(GO:0007097)
0.3	7.1	GO:0000027	ribosomal large subunit assembly(GO:0000027)
0.3	11.1	GO:0006805	xenobiotic metabolic process(GO:0006805)
0.3	3.0	GO:2000505	regulation of energy homeostasis(GO:2000505)
0.3	4.3	GO:0042761	very long-chain fatty acid biosynthetic process(GO:0042761)
0.2	8.2	GO:0042246	tissue regeneration(GO:0042246)
0.2	6.4	GO:0042036	negative regulation of cytokine biosynthetic process(GO:0042036)
0.2	1.1	GO:0090274	positive regulation of pancreatic juice secretion(GO:0090187) positive regulation of somatostatin secretion(GO:0090274)
0.2	0.9	GO:0031547	brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
0.2	4.7	GO:0061436	establishment of skin barrier(GO:0061436)
0.2	4.7	GO:0050860	negative regulation of T cell receptor signaling pathway(GO:0050860)
0.2	2.5	GO:0051764	actin crosslink formation(GO:0051764)
0.2	1.4	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.2	7.0	GO:0045214	sarcomere organization(GO:0045214)
0.2	7.1	GO:0005978	glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.2	1.1	GO:0050957	equilibrioception(GO:0050957)
0.2	12.8	GO:0045445	myoblast differentiation(GO:0045445)
0.2	1.6	GO:0018026	peptidyl-lysine monomethylation(GO:0018026)
0.2	1.9	GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.2	8.1	GO:0001707	mesoderm formation(GO:0001707)
0.2	1.2	GO:0070601	centromeric sister chromatid cohesion(GO:0070601)
0.2	5.4	GO:0048247	lymphocyte chemotaxis(GO:0048247)
0.2	0.9	GO:0033564	anterior/posterior axon guidance(GO:0033564)
0.1	1.5	GO:0006488	dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1	0.4	GO:0098972	dendritic transport of mitochondrion(GO:0098939) anterograde dendritic transport of mitochondrion(GO:0098972)
0.1	0.5	GO:0045721	negative regulation of gluconeogenesis(GO:0045721)
0.1	8.8	GO:0098869	cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.1	2.9	GO:0045736	negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736)
0.1	5.7	GO:0006360	transcription from RNA polymerase I promoter(GO:0006360)
0.1	1.2	GO:2000773	negative regulation of cellular senescence(GO:2000773)
0.1	4.2	GO:0009268	response to pH(GO:0009268)
0.1	1.6	GO:0050892	intestinal absorption(GO:0050892)
0.1	2.4	GO:0060259	regulation of feeding behavior(GO:0060259)
0.1	2.5	GO:0010842	retina layer formation(GO:0010842)
0.1	2.5	GO:0046513	ceramide biosynthetic process(GO:0046513)
0.1	0.5	GO:0030222	response to nematode(GO:0009624) eosinophil differentiation(GO:0030222)
0.1	4.2	GO:0006487	protein N-linked glycosylation(GO:0006487)
0.1	2.0	GO:0034260	negative regulation of GTPase activity(GO:0034260)
0.1	0.2	GO:0032298	positive regulation of DNA-dependent DNA replication initiation(GO:0032298)
0.1	1.4	GO:0007635	chemosensory behavior(GO:0007635)
0.1	0.6	GO:1902969	mitotic DNA replication(GO:1902969)
0.1	1.4	GO:0035641	locomotory exploration behavior(GO:0035641)
0.1	6.1	GO:1902476	chloride transmembrane transport(GO:1902476)
0.1	9.4	GO:0006865	amino acid transport(GO:0006865)
0.1	1.7	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.1	69.4	GO:0050911	detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.1	0.6	GO:0050907	detection of chemical stimulus involved in sensory perception(GO:0050907)
0.1	8.7	GO:0007606	sensory perception of chemical stimulus(GO:0007606)
0.0	0.3	GO:0032460	negative regulation of protein oligomerization(GO:0032460)
0.0	4.2	GO:0035023	regulation of Rho protein signal transduction(GO:0035023)
0.0	2.1	GO:0033209	tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0	1.3	GO:0048488	synaptic vesicle endocytosis(GO:0048488)
0.0	3.3	GO:0043433	negative regulation of sequence-specific DNA binding transcription factor activity(GO:0043433)
0.0	2.1	GO:0045582	positive regulation of T cell differentiation(GO:0045582)
0.0	0.8	GO:0030857	negative regulation of epithelial cell differentiation(GO:0030857)
0.0	2.1	GO:0043488	regulation of mRNA stability(GO:0043488)
0.0	3.2	GO:0008360	regulation of cell shape(GO:0008360)
0.0	0.8	GO:0050873	brown fat cell differentiation(GO:0050873)
0.0	1.7	GO:0010923	negative regulation of phosphatase activity(GO:0010923)
0.0	0.3	GO:2000738	positive regulation of stem cell differentiation(GO:2000738)
0.0	0.4	GO:0007032	endosome organization(GO:0007032)
0.0	1.5	GO:0007160	cell-matrix adhesion(GO:0007160)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
26.4	79.1	GO:0045257	mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) fumarate reductase complex(GO:0045283)
15.9	95.2	GO:0034363	intermediate-density lipoprotein particle(GO:0034363)
15.0	15.0	GO:0045281	respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281)
10.4	82.9	GO:0000275	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
6.7	74.2	GO:0005750	mitochondrial respiratory chain complex III(GO:0005750)
6.4	32.2	GO:0070195	growth hormone receptor complex(GO:0070195)
5.8	92.2	GO:0005751	mitochondrial respiratory chain complex IV(GO:0005751)
5.7	17.1	GO:0044214	spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
5.2	15.5	GO:0090534	longitudinal sarcoplasmic reticulum(GO:0014801) calcium ion-transporting ATPase complex(GO:0090534)
5.0	64.4	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
4.9	29.4	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
4.5	40.2	GO:0030314	junctional membrane complex(GO:0030314)
4.3	13.0	GO:0097444	spine apparatus(GO:0097444)
3.9	31.3	GO:0005753	mitochondrial proton-transporting ATP synthase complex(GO:0005753)
3.9	11.6	GO:0005962	mitochondrial isocitrate dehydrogenase complex (NAD+)(GO:0005962) isocitrate dehydrogenase complex (NAD+)(GO:0045242)
3.3	167.5	GO:0030964	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
3.1	9.4	GO:0005744	mitochondrial inner membrane presequence translocase complex(GO:0005744)
3.1	15.4	GO:0044316	cone cell pedicle(GO:0044316)
3.0	15.1	GO:0005927	muscle tendon junction(GO:0005927)
3.0	12.0	GO:0001405	presequence translocase-associated import motor(GO:0001405)
2.9	71.7	GO:0031528	microvillus membrane(GO:0031528)
2.7	10.9	GO:1990584	cardiac Troponin complex(GO:1990584)
2.6	33.8	GO:0031983	vesicle lumen(GO:0031983)
2.5	12.4	GO:0070069	cytochrome complex(GO:0070069)
2.4	30.7	GO:0046581	intercellular canaliculus(GO:0046581)
2.3	18.1	GO:0005577	fibrinogen complex(GO:0005577)
2.3	24.8	GO:0031143	pseudopodium(GO:0031143)
2.2	24.3	GO:0070469	respiratory chain(GO:0070469)
2.1	43.8	GO:0005865	striated muscle thin filament(GO:0005865)
2.1	12.4	GO:0097512	cardiac myofibril(GO:0097512)
1.8	5.4	GO:0031680	G-protein beta/gamma-subunit complex(GO:0031680)
1.8	19.5	GO:0043202	lysosomal lumen(GO:0043202)
1.7	8.6	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
1.7	49.6	GO:0031304	intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
1.6	19.4	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
1.4	18.3	GO:0032426	stereocilium tip(GO:0032426)
1.4	17.9	GO:0061702	inflammasome complex(GO:0061702)
1.2	29.8	GO:0034364	high-density lipoprotein particle(GO:0034364)
1.2	14.3	GO:0045239	tricarboxylic acid cycle enzyme complex(GO:0045239)
1.1	12.5	GO:0072546	ER membrane protein complex(GO:0072546)
1.1	1.1	GO:0000814	ESCRT II complex(GO:0000814)
1.1	54.8	GO:0009295	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
1.1	9.5	GO:0045254	pyruvate dehydrogenase complex(GO:0045254)
1.0	4.0	GO:0045098	type III intermediate filament(GO:0045098)
0.9	9.4	GO:0097550	transcriptional preinitiation complex(GO:0097550)
0.9	0.9	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.9	4.4	GO:1990769	proximal neuron projection(GO:1990769)
0.9	18.3	GO:0030056	hemidesmosome(GO:0030056)
0.8	125.4	GO:0030018	Z disc(GO:0030018)
0.8	191.2	GO:0005743	mitochondrial inner membrane(GO:0005743)
0.8	2.4	GO:0048269	methionine adenosyltransferase complex(GO:0048269)
0.8	8.7	GO:0001527	microfibril(GO:0001527) fibril(GO:0043205)
0.8	18.8	GO:0045120	pronucleus(GO:0045120)
0.8	21.1	GO:0005763	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.8	3.8	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
0.7	78.4	GO:0072562	blood microparticle(GO:0072562)
0.7	157.2	GO:0005759	mitochondrial matrix(GO:0005759)
0.7	28.2	GO:0016235	aggresome(GO:0016235)
0.7	5.3	GO:0097443	sorting endosome(GO:0097443)
0.6	28.9	GO:0001917	photoreceptor inner segment(GO:0001917)
0.5	11.5	GO:0098644	complex of collagen trimers(GO:0098644)
0.5	7.1	GO:0033179	proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.5	5.4	GO:0071439	clathrin complex(GO:0071439)
0.5	19.3	GO:0009925	basal plasma membrane(GO:0009925)
0.5	31.6	GO:0001725	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.5	49.4	GO:0005604	basement membrane(GO:0005604)
0.5	2.0	GO:0005968	Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.5	101.3	GO:0005770	late endosome(GO:0005770)
0.5	17.4	GO:0016459	myosin complex(GO:0016459)
0.5	6.2	GO:0099634	postsynaptic specialization membrane(GO:0099634)
0.5	4.7	GO:1990635	proximal dendrite(GO:1990635)
0.5	4.2	GO:0005915	zonula adherens(GO:0005915)
0.5	5.7	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.5	25.5	GO:0034707	chloride channel complex(GO:0034707)
0.4	8.6	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.4	3.4	GO:0044233	ER-mitochondrion membrane contact site(GO:0044233)
0.4	1.2	GO:0033557	Slx1-Slx4 complex(GO:0033557)
0.4	6.4	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.4	18.3	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.4	1.5	GO:0043541	UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.4	1.1	GO:0030956	glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.3	3.8	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.3	39.1	GO:0005923	bicellular tight junction(GO:0005923)
0.3	9.7	GO:0042470	melanosome(GO:0042470) pigment granule(GO:0048770)
0.3	2.5	GO:0031211	serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.3	12.9	GO:0030017	sarcomere(GO:0030017)
0.3	1.7	GO:0005726	perichromatin fibrils(GO:0005726)
0.3	1.4	GO:0000138	Golgi trans cisterna(GO:0000138)
0.3	1.3	GO:0032591	dendritic spine membrane(GO:0032591)
0.3	14.1	GO:0043198	dendritic shaft(GO:0043198)
0.3	13.3	GO:0031903	peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.2	1.6	GO:0045179	apical cortex(GO:0045179)
0.2	14.5	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.2	2.2	GO:0000177	cytoplasmic exosome (RNase complex)(GO:0000177)
0.2	38.2	GO:0031966	mitochondrial membrane(GO:0031966)
0.2	7.8	GO:0005777	peroxisome(GO:0005777) microbody(GO:0042579)
0.2	3.3	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.2	1.2	GO:0031415	NatA complex(GO:0031415)
0.2	8.1	GO:0045171	intercellular bridge(GO:0045171)
0.2	7.1	GO:0030864	cortical actin cytoskeleton(GO:0030864)
0.2	4.7	GO:0001772	immunological synapse(GO:0001772)
0.2	64.3	GO:0005667	transcription factor complex(GO:0005667)
0.2	29.8	GO:0016323	basolateral plasma membrane(GO:0016323)
0.2	0.3	GO:0097451	glial limiting end-foot(GO:0097451)
0.1	4.6	GO:0005903	brush border(GO:0005903)
0.1	3.4	GO:0005902	microvillus(GO:0005902)
0.1	2.9	GO:0001891	phagocytic cup(GO:0001891)
0.1	1.8	GO:0044292	dendrite terminus(GO:0044292)
0.1	1.7	GO:0071565	nBAF complex(GO:0071565)
0.1	4.2	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.1	2.0	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.1	1.4	GO:0030126	COPI vesicle coat(GO:0030126)
0.1	3.6	GO:1904115	axon cytoplasm(GO:1904115)
0.1	22.2	GO:0005911	cell-cell junction(GO:0005911)
0.1	1.7	GO:0030867	rough endoplasmic reticulum membrane(GO:0030867)
0.1	16.0	GO:0045177	apical part of cell(GO:0045177)
0.1	1.3	GO:0031985	Golgi cisterna(GO:0031985)
0.1	1.7	GO:0080008	Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1	39.4	GO:0005789	endoplasmic reticulum membrane(GO:0005789)
0.1	59.5	GO:0005739	mitochondrion(GO:0005739)
0.1	9.8	GO:0061695	transferase complex, transferring phosphorus-containing groups(GO:0061695)
0.0	0.3	GO:0032590	dendrite membrane(GO:0032590)
0.0	79.5	GO:0070062	extracellular exosome(GO:0070062)
0.0	1.1	GO:0045095	keratin filament(GO:0045095)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
27.7	83.1	GO:0070653	high-density lipoprotein particle receptor binding(GO:0070653)
26.4	79.1	GO:0008177	succinate dehydrogenase (ubiquinone) activity(GO:0008177)
15.8	63.3	GO:0003989	acetyl-CoA carboxylase activity(GO:0003989)
15.0	15.0	GO:0000104	succinate dehydrogenase activity(GO:0000104)
12.6	50.3	GO:0070546	L-phenylalanine aminotransferase activity(GO:0070546)
11.9	47.7	GO:0048039	ubiquinone binding(GO:0048039)
11.1	33.3	GO:0004807	triose-phosphate isomerase activity(GO:0004807)
9.6	47.9	GO:0004614	phosphoglucomutase activity(GO:0004614)
9.2	46.2	GO:0051373	FATZ binding(GO:0051373)
8.9	26.6	GO:0052743	phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485) inositol tetrakisphosphate phosphatase activity(GO:0052743)
8.7	43.4	GO:0043532	angiostatin binding(GO:0043532)
8.1	32.2	GO:0004903	growth hormone receptor activity(GO:0004903)
7.2	21.5	GO:0036468	aromatic-L-amino-acid decarboxylase activity(GO:0004058) L-dopa decarboxylase activity(GO:0036468)
6.5	45.3	GO:0070095	fructose-6-phosphate binding(GO:0070095)
5.8	103.8	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
5.8	46.1	GO:0016681	ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
5.7	45.7	GO:0008172	S-methyltransferase activity(GO:0008172)
5.6	22.5	GO:0003997	acyl-CoA oxidase activity(GO:0003997)
5.1	15.2	GO:0004924	oncostatin-M receptor activity(GO:0004924)
5.0	49.9	GO:0051959	dynein light intermediate chain binding(GO:0051959)
4.9	14.8	GO:0004466	long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
4.9	29.4	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
4.9	14.7	GO:0004657	proline dehydrogenase activity(GO:0004657)
4.9	14.6	GO:0008520	L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
4.8	28.8	GO:0008970	phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
4.3	43.5	GO:0015143	urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
4.2	12.5	GO:0047025	3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
4.1	20.7	GO:0008453	alanine-glyoxylate transaminase activity(GO:0008453)
4.0	12.1	GO:0004618	phosphoglycerate kinase activity(GO:0004618)
4.0	12.1	GO:0046911	metal chelating activity(GO:0046911)
4.0	11.9	GO:0016509	long-chain-enoyl-CoA hydratase activity(GO:0016508) long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
3.9	31.0	GO:0008430	selenium binding(GO:0008430)
3.8	30.3	GO:0070053	thrombospondin receptor activity(GO:0070053)
3.7	15.0	GO:0003973	(S)-2-hydroxy-acid oxidase activity(GO:0003973)
3.7	25.7	GO:0052832	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832)
3.5	10.4	GO:0008948	oxaloacetate decarboxylase activity(GO:0008948)
3.5	104.0	GO:0004129	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
3.3	16.3	GO:0004017	adenylate kinase activity(GO:0004017)
3.2	19.5	GO:0031419	cobalamin binding(GO:0031419)
3.1	9.2	GO:0008489	UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity(GO:0008489)
3.0	92.2	GO:0015020	glucuronosyltransferase activity(GO:0015020)
2.9	11.6	GO:0004449	isocitrate dehydrogenase (NAD+) activity(GO:0004449)
2.8	75.2	GO:0008137	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
2.8	8.3	GO:0036478	tyrosine 3-monooxygenase activator activity(GO:0036470) L-dopa decarboxylase activator activity(GO:0036478)
2.7	19.2	GO:0004062	aryl sulfotransferase activity(GO:0004062)
2.7	10.9	GO:0030172	troponin C binding(GO:0030172)
2.7	42.6	GO:0051371	muscle alpha-actinin binding(GO:0051371)
2.6	7.7	GO:0004736	pyruvate carboxylase activity(GO:0004736)
2.5	49.7	GO:0034185	apolipoprotein binding(GO:0034185)
2.5	9.9	GO:0050252	retinol O-fatty-acyltransferase activity(GO:0050252)
2.4	12.1	GO:0031798	type 1 metabotropic glutamate receptor binding(GO:0031798)
2.4	7.1	GO:0031177	phosphopantetheine binding(GO:0031177)
2.2	2.2	GO:1990763	arrestin family protein binding(GO:1990763)
2.1	18.7	GO:0043184	vascular endothelial growth factor receptor 2 binding(GO:0043184)
2.0	6.1	GO:0004359	glutaminase activity(GO:0004359)
2.0	17.9	GO:0005000	vasopressin receptor activity(GO:0005000)
2.0	8.0	GO:1904288	BAT3 complex binding(GO:1904288)
2.0	7.8	GO:0004487	methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
1.9	13.6	GO:0004957	prostaglandin E receptor activity(GO:0004957)
1.9	15.4	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
1.9	13.1	GO:0030160	GKAP/Homer scaffold activity(GO:0030160)
1.9	9.4	GO:0032557	pyrimidine ribonucleotide binding(GO:0032557)
1.9	5.6	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
1.8	48.5	GO:0019825	oxygen binding(GO:0019825)
1.8	5.4	GO:0031726	CCR1 chemokine receptor binding(GO:0031726)
1.8	25.0	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
1.8	19.6	GO:0005375	copper ion transmembrane transporter activity(GO:0005375)
1.7	34.5	GO:0004550	nucleoside diphosphate kinase activity(GO:0004550)
1.7	6.8	GO:0031731	CCR6 chemokine receptor binding(GO:0031731)
1.7	5.0	GO:0004140	dephospho-CoA kinase activity(GO:0004140)
1.7	5.0	GO:0004307	ethanolaminephosphotransferase activity(GO:0004307)
1.6	14.6	GO:0003995	acyl-CoA dehydrogenase activity(GO:0003995)
1.6	9.3	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
1.5	19.2	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
1.5	33.8	GO:0070006	metalloaminopeptidase activity(GO:0070006)
1.4	17.2	GO:0031730	CCR5 chemokine receptor binding(GO:0031730)
1.4	9.9	GO:0004064	arylesterase activity(GO:0004064)
1.4	7.0	GO:0004416	hydroxyacylglutathione hydrolase activity(GO:0004416)
1.4	6.8	GO:0086062	voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
1.4	35.5	GO:0017147	Wnt-protein binding(GO:0017147)
1.4	36.5	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
1.3	12.1	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
1.3	18.6	GO:0005391	sodium:potassium-exchanging ATPase activity(GO:0005391)
1.3	19.2	GO:0035497	cAMP response element binding(GO:0035497)
1.3	3.8	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
1.2	6.1	GO:0000213	tRNA-intron endonuclease activity(GO:0000213)
1.2	4.9	GO:0045174	oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
1.2	9.5	GO:0034604	pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
1.1	8.0	GO:0016018	cyclosporin A binding(GO:0016018)
1.1	5.7	GO:0048248	CXCR3 chemokine receptor binding(GO:0048248)
1.1	30.9	GO:0008395	steroid hydroxylase activity(GO:0008395)
1.1	5.4	GO:0090554	phosphatidylcholine-translocating ATPase activity(GO:0090554) phosphatidylethanolamine-translocating ATPase activity(GO:0090555)
1.1	8.6	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
1.1	10.8	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
1.0	10.5	GO:0019808	polyamine binding(GO:0019808)
1.0	18.8	GO:0031005	filamin binding(GO:0031005)
1.0	9.4	GO:0032052	bile acid binding(GO:0032052)
1.0	6.2	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
1.0	7.1	GO:0035251	UDP-glucosyltransferase activity(GO:0035251)
0.9	3.7	GO:0070568	guanylyltransferase activity(GO:0070568)
0.9	22.4	GO:0008308	voltage-gated anion channel activity(GO:0008308)
0.9	6.4	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.9	10.9	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.9	16.9	GO:0017081	chloride channel regulator activity(GO:0017081)
0.9	16.8	GO:0042056	chemoattractant activity(GO:0042056)
0.9	26.2	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.9	7.8	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.9	15.5	GO:0044548	S100 protein binding(GO:0044548)
0.8	4.2	GO:0070097	delta-catenin binding(GO:0070097)
0.8	2.5	GO:0047057	oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.8	52.7	GO:0038024	cargo receptor activity(GO:0038024)
0.8	11.0	GO:0010181	FMN binding(GO:0010181)
0.8	6.2	GO:0043495	protein anchor(GO:0043495)
0.7	5.7	GO:0001055	RNA polymerase II activity(GO:0001055)
0.7	25.7	GO:0008307	structural constituent of muscle(GO:0008307)
0.7	2.0	GO:0004663	Rab geranylgeranyltransferase activity(GO:0004663)
0.7	16.3	GO:0009055	electron carrier activity(GO:0009055)
0.7	22.3	GO:0017080	sodium channel regulator activity(GO:0017080)
0.7	5.3	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021) vascular endothelial growth factor binding(GO:0038085)
0.7	2.6	GO:0055100	adiponectin binding(GO:0055100)
0.6	4.5	GO:0038062	protein tyrosine kinase collagen receptor activity(GO:0038062)
0.6	3.7	GO:0008474	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.6	4.8	GO:1990247	N6-methyladenosine-containing RNA binding(GO:1990247)
0.6	2.4	GO:0004977	melanocortin receptor activity(GO:0004977)
0.6	23.2	GO:0016836	hydro-lyase activity(GO:0016836)
0.6	8.1	GO:0008484	sulfuric ester hydrolase activity(GO:0008484)
0.6	3.4	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.6	1.7	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.5	2.2	GO:0001733	galactosylceramide sulfotransferase activity(GO:0001733)
0.5	10.6	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.5	11.5	GO:0015114	phosphate ion transmembrane transporter activity(GO:0015114)
0.5	4.1	GO:0019855	calcium channel inhibitor activity(GO:0019855)
0.5	5.6	GO:0009931	calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.5	2.5	GO:0031849	olfactory receptor binding(GO:0031849)
0.5	2.5	GO:0016454	serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.5	7.3	GO:0050308	sugar-phosphatase activity(GO:0050308)
0.5	20.5	GO:0016651	oxidoreductase activity, acting on NAD(P)H(GO:0016651)
0.5	3.4	GO:0043423	3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.5	3.8	GO:0046790	virion binding(GO:0046790)
0.5	3.7	GO:0048273	mitogen-activated protein kinase p38 binding(GO:0048273)
0.5	6.5	GO:0033038	bitter taste receptor activity(GO:0033038)
0.5	26.1	GO:0050840	extracellular matrix binding(GO:0050840)
0.5	6.4	GO:0004576	oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.4	4.9	GO:0004032	alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.4	1.3	GO:0042903	tubulin deacetylase activity(GO:0042903)
0.4	12.1	GO:0004623	phospholipase A2 activity(GO:0004623)
0.4	19.8	GO:0004714	transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.4	2.9	GO:0097322	7SK snRNA binding(GO:0097322)
0.4	3.2	GO:0015129	lactate transmembrane transporter activity(GO:0015129)
0.4	1.6	GO:0004082	bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.4	17.9	GO:0030170	pyridoxal phosphate binding(GO:0030170)
0.4	15.4	GO:0030552	cAMP binding(GO:0030552)
0.4	3.7	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.4	24.4	GO:0048306	calcium-dependent protein binding(GO:0048306)
0.4	1.1	GO:0004040	amidase activity(GO:0004040) glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.4	1.1	GO:0032217	riboflavin transporter activity(GO:0032217)
0.4	8.2	GO:0046965	retinoid X receptor binding(GO:0046965)
0.3	2.4	GO:0001162	RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.3	3.0	GO:0004887	thyroid hormone receptor activity(GO:0004887)
0.3	10.9	GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.3	2.0	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.3	2.9	GO:0032050	clathrin heavy chain binding(GO:0032050)
0.3	16.3	GO:0001221	transcription cofactor binding(GO:0001221)
0.3	1.6	GO:0005324	long-chain fatty acid transporter activity(GO:0005324)
0.3	1.4	GO:0033188	sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.3	7.2	GO:0004190	aspartic-type endopeptidase activity(GO:0004190)
0.3	4.8	GO:0048020	CCR chemokine receptor binding(GO:0048020)
0.3	0.8	GO:0031783	corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.2	3.6	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.2	4.3	GO:0033549	MAP kinase phosphatase activity(GO:0033549)
0.2	1.6	GO:0046976	histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.2	2.2	GO:0047617	acyl-CoA hydrolase activity(GO:0047617)
0.2	7.1	GO:0005484	SNAP receptor activity(GO:0005484)
0.2	2.3	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.2	3.8	GO:0005521	lamin binding(GO:0005521)
0.2	4.9	GO:0004890	GABA-A receptor activity(GO:0004890)
0.2	0.9	GO:0005042	netrin receptor activity(GO:0005042)
0.2	6.4	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.2	15.9	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.2	25.5	GO:0005125	cytokine activity(GO:0005125)
0.2	2.9	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.2	2.7	GO:0008301	DNA binding, bending(GO:0008301)
0.2	6.5	GO:0048487	beta-tubulin binding(GO:0048487)
0.2	2.2	GO:0017134	fibroblast growth factor binding(GO:0017134)
0.2	6.6	GO:0030544	Hsp70 protein binding(GO:0030544)
0.1	12.5	GO:0008013	beta-catenin binding(GO:0008013)
0.1	1.0	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1	4.5	GO:0034062	DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.1	7.8	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.1	3.6	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.1	4.7	GO:0043531	ADP binding(GO:0043531)
0.1	13.2	GO:0008201	heparin binding(GO:0008201)
0.1	0.7	GO:0048018	receptor agonist activity(GO:0048018)
0.1	2.6	GO:0051393	alpha-actinin binding(GO:0051393)
0.1	1.2	GO:0008821	crossover junction endodeoxyribonuclease activity(GO:0008821)
0.1	8.0	GO:0005496	steroid binding(GO:0005496)
0.1	0.9	GO:0015035	protein disulfide oxidoreductase activity(GO:0015035)
0.1	1.8	GO:0019789	SUMO transferase activity(GO:0019789)
0.1	3.5	GO:0001786	phosphatidylserine binding(GO:0001786)
0.1	2.0	GO:0008327	methyl-CpG binding(GO:0008327)
0.1	2.2	GO:0008198	ferrous iron binding(GO:0008198)
0.1	9.5	GO:0016503	pheromone receptor activity(GO:0016503)
0.1	37.6	GO:0005549	odorant binding(GO:0005549)
0.1	6.1	GO:0003730	mRNA 3'-UTR binding(GO:0003730)
0.1	3.6	GO:0005080	protein kinase C binding(GO:0005080)
0.1	11.9	GO:0044822	mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.1	1.6	GO:0005212	structural constituent of eye lens(GO:0005212)
0.1	6.8	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1	2.9	GO:0030971	receptor tyrosine kinase binding(GO:0030971)
0.1	5.3	GO:0030674	protein binding, bridging(GO:0030674)
0.1	0.9	GO:0016881	acid-amino acid ligase activity(GO:0016881)
0.0	0.2	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0	0.6	GO:0008527	taste receptor activity(GO:0008527)
0.0	31.8	GO:0004984	olfactory receptor activity(GO:0004984)
0.0	0.3	GO:0017151	DEAD/H-box RNA helicase binding(GO:0017151)
0.0	0.4	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0	1.6	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0	2.5	GO:0004197	cysteine-type endopeptidase activity(GO:0004197)
0.0	3.4	GO:0016853	isomerase activity(GO:0016853)
0.0	2.5	GO:0051015	actin filament binding(GO:0051015)
0.0	4.4	GO:0001077	transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0	2.8	GO:0008514	organic anion transmembrane transporter activity(GO:0008514)
0.0	0.1	GO:0016933	extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0	0.4	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.2	24.0	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
2.0	107.7	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.9	56.5	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.8	2.4	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.8	54.8	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.7	9.9	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.6	18.1	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.5	26.2	PID ATF2 PATHWAY	ATF-2 transcription factor network
0.5	40.7	PID CMYB PATHWAY	C-MYB transcription factor network
0.5	21.0	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.4	14.6	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.4	17.2	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.4	19.5	PID ARF6 PATHWAY	Arf6 signaling events
0.4	8.6	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.4	12.1	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.4	10.5	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.4	12.9	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.4	14.6	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.3	2.9	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.3	71.4	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.2	3.4	ST G ALPHA S PATHWAY	G alpha s Pathway
0.2	5.7	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.2	5.6	ST P38 MAPK PATHWAY	p38 MAPK Pathway
0.2	10.3	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.2	5.2	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.2	3.8	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.2	2.4	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.2	8.3	PID FGF PATHWAY	FGF signaling pathway
0.2	2.0	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.1	4.2	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.1	0.9	PID S1P S1P3 PATHWAY	S1P3 pathway
0.1	6.5	PID E2F PATHWAY	E2F transcription factor network
0.1	5.9	PID LKB1 PATHWAY	LKB1 signaling events
0.1	2.6	ST G ALPHA I PATHWAY	G alpha i Pathway
0.1	1.7	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.1	1.5	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events
0.1	5.0	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.1	1.3	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.1	1.3	PID INTEGRIN CS PATHWAY	Integrin family cell surface interactions
0.1	2.7	PID INSULIN PATHWAY	Insulin Pathway
0.1	0.9	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.0	0.9	PID AP1 PATHWAY	AP-1 transcription factor network
0.0	0.9	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.0	2.1	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.0	0.5	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
0.0	1.2	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.0	1.9	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
10.4	176.1	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
7.3	471.4	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
6.6	106.2	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
4.9	48.9	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
4.2	168.3	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
3.7	44.8	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
3.2	51.1	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
3.1	69.1	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
3.0	56.7	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
2.8	25.4	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
2.7	21.6	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
2.6	33.9	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
2.6	46.2	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
2.4	66.1	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
2.2	44.9	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
2.0	24.0	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
1.9	56.2	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
1.9	26.5	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
1.8	20.2	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
1.8	60.3	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
1.8	20.0	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
1.7	13.6	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
1.7	18.2	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
1.6	19.5	REACTOME LIPOPROTEIN METABOLISM	Genes involved in Lipoprotein metabolism
1.6	33.6	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
1.5	19.6	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
1.5	57.9	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
1.5	19.2	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
1.3	17.2	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
1.1	15.4	REACTOME FGFR4 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR4 ligand binding and activation
1.1	22.7	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
1.1	13.9	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
1.1	41.2	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
1.0	12.2	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.9	8.1	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.8	32.8	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.8	11.7	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.8	27.8	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.8	16.3	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.7	13.4	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.7	11.5	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.7	6.9	REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE	Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.7	9.5	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.7	0.7	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.6	20.6	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.6	15.5	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.5	18.4	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.5	9.3	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.4	8.1	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.4	5.0	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.4	6.1	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.4	3.8	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.4	5.7	REACTOME VIRAL MESSENGER RNA SYNTHESIS	Genes involved in Viral Messenger RNA Synthesis
0.4	13.0	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.4	17.3	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.3	7.1	REACTOME GLUCOSE METABOLISM	Genes involved in Glucose metabolism
0.3	5.3	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.3	2.9	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.3	3.3	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.3	4.0	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.3	3.7	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.3	8.3	REACTOME NUCLEAR SIGNALING BY ERBB4	Genes involved in Nuclear signaling by ERBB4
0.2	3.7	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.2	23.8	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.2	12.5	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.2	2.9	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.2	22.9	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.2	2.5	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.2	10.2	REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS	Genes involved in Glycerophospholipid biosynthesis
0.2	7.9	REACTOME ASPARAGINE N LINKED GLYCOSYLATION	Genes involved in Asparagine N-linked glycosylation
0.1	9.3	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.1	1.0	REACTOME G ALPHA S SIGNALLING EVENTS	Genes involved in G alpha (s) signalling events
0.1	2.9	REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE	Genes involved in Nitric oxide stimulates guanylate cyclase
0.1	7.4	REACTOME RNA POL I RNA POL III AND MITOCHONDRIAL TRANSCRIPTION	Genes involved in RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
0.1	2.6	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	1.4	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.9	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	0.1	REACTOME LIGAND GATED ION CHANNEL TRANSPORT	Genes involved in Ligand-gated ion channel transport
0.0	0.5	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0	0.9	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+

Results for Nr2f1_Nr4a1

Z-value: 1.37

Motif logo

Transcription factors associated with Nr2f1_Nr4a1

Activity-expression correlation:

Activity profile of Nr2f1_Nr4a1 motif

Sorted Z-values of Nr2f1_Nr4a1 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of Nr2f1_Nr4a1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: