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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Nfix

Z-value: 0.80

Motif logo

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Transcription factors associated with Nfix

Gene Symbol Gene ID Gene Info

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nf1xrn6_v1_chr19_-_25914689_259146960.359.0e-11Click!

Activity profile of Nfix motif

Sorted Z-values of Nfix motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr10_+_53740841 53.70 ENSRNOT00000004295
Myh2
myosin heavy chain 2
chr14_-_19191863 37.92 ENSRNOT00000003921
Alb
albumin
chr8_+_50537009 28.10 ENSRNOT00000080658
Apoa4
apolipoprotein A4
chr13_+_83073544 27.99 ENSRNOT00000066119
ENSRNOT00000079796
ENSRNOT00000077070
Dpt
dermatopontin
chr13_+_83073866 27.53 ENSRNOT00000075996
Dpt
dermatopontin
chr17_-_389967 26.43 ENSRNOT00000023865
Fbp2
fructose-bisphosphatase 2
chr10_+_53778662 26.21 ENSRNOT00000045718
Myh2
myosin heavy chain 2
chr2_-_188596222 24.27 ENSRNOT00000027920
Efna1
ephrin A1
chr2_-_233743866 23.00 ENSRNOT00000087062
Enpep
glutamyl aminopeptidase
chr7_+_38819771 22.37 ENSRNOT00000006109
Lum
lumican
chr15_-_41595345 19.14 ENSRNOT00000019639
Sgcg
sarcoglycan, gamma
chr13_-_90602365 18.52 ENSRNOT00000009344
Casq1
calsequestrin 1
chr14_+_22806132 18.36 ENSRNOT00000002728
Ugt2b10
UDP glucuronosyltransferase 2 family, polypeptide B10
chr10_-_88036040 18.05 ENSRNOT00000018851
Krt13
keratin 13
chr13_-_82005741 17.87 ENSRNOT00000076404
Mettl11b
methyltransferase like 11B
chr13_-_82006005 15.85 ENSRNOT00000039581
Mettl11b
methyltransferase like 11B
chr1_-_162385575 15.46 ENSRNOT00000016540
Thrsp
thyroid hormone responsive
chr20_+_40769586 15.41 ENSRNOT00000001079
Fabp7
fatty acid binding protein 7
chr7_-_143523457 14.89 ENSRNOT00000012943
ENSRNOT00000082264
Krt4
keratin 4
chr1_+_282568287 13.68 ENSRNOT00000015997
Ces2i
carboxylesterase 2I
chr4_+_100218661 12.97 ENSRNOT00000079415
Tmem150a
transmembrane protein 150A
chr2_-_45518502 12.80 ENSRNOT00000014627
Hspb3
heat shock protein family B (small) member 3
chr2_+_188528979 12.67 ENSRNOT00000087934
Thbs3
thrombospondin 3
chr14_+_7113544 11.66 ENSRNOT00000038188
Hsd17b13
hydroxysteroid (17-beta) dehydrogenase 13
chr1_+_41192824 11.49 ENSRNOT00000082133
Esr1
estrogen receptor 1
chrX_+_134940615 11.20 ENSRNOT00000005604
Xpnpep2
X-prolyl aminopeptidase 2
chr3_+_58965552 11.09 ENSRNOT00000002068
Map3k20
mitogen-activated protein kinase kinase kinase 20
chr8_-_84522588 10.98 ENSRNOT00000076213
Mlip
muscular LMNA-interacting protein
chr7_-_30105132 10.80 ENSRNOT00000091227
Nr1h4
nuclear receptor subfamily 1, group H, member 4
chr16_+_72401887 10.71 ENSRNOT00000074449
LOC100910163
uncharacterized LOC100910163
chr17_-_15511972 10.33 ENSRNOT00000074041
Aspnl1
asporin-like 1
chr4_+_7076759 10.06 ENSRNOT00000066598
Smarcd3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr2_-_184951950 10.04 ENSRNOT00000093486
Fam160a1
family with sequence similarity 160, member A1
chr16_+_72388880 9.91 ENSRNOT00000072459
LOC684871
similar to Protein C8orf4 (Thyroid cancer protein 1) (TC-1)
chr16_+_6962722 9.65 ENSRNOT00000023330
Mustn1
musculoskeletal, embryonic nuclear protein 1
chr9_-_52238564 9.42 ENSRNOT00000005073
Col5a2
collagen type V alpha 2 chain
chrX_+_53053609 9.26 ENSRNOT00000058357
Dmd
dystrophin
chr1_+_144239020 8.62 ENSRNOT00000032106
Adamtsl3
ADAMTS-like 3
chr1_+_41323194 8.53 ENSRNOT00000026350
Esr1
estrogen receptor 1
chr16_+_2537248 8.29 ENSRNOT00000017995
Asb14
ankyrin repeat and SOCS box-containing 14
chr5_-_102786331 8.24 ENSRNOT00000086635
Bnc2
basonuclin 2
chrX_+_77278240 8.00 ENSRNOT00000085653
Pgk1
phosphoglycerate kinase 1
chr12_-_6740714 7.55 ENSRNOT00000001205
Medag
mesenteric estrogen-dependent adipogenesis
chr1_+_201620642 7.43 ENSRNOT00000093674
Dmbt1
deleted in malignant brain tumors 1
chr2_-_80667481 6.99 ENSRNOT00000016784
Trio
trio Rho guanine nucleotide exchange factor
chr5_-_93244202 6.90 ENSRNOT00000075474
Ptprd
protein tyrosine phosphatase, receptor type, D
chr8_-_107952530 6.35 ENSRNOT00000052043
Cldn18
claudin 18
chr13_-_50549981 6.26 ENSRNOT00000003918
ENSRNOT00000080486
Golt1a
golgi transport 1A
chr2_+_222792999 6.14 ENSRNOT00000036228
AABR07013086.1

chrX_+_124631881 5.87 ENSRNOT00000009329
Atp1b4
ATPase Na+/K+ transporting family member beta 4
chr1_-_101596822 5.85 ENSRNOT00000028490
Fgf21
fibroblast growth factor 21
chrX_-_72078551 5.82 ENSRNOT00000076978
Rps4x
ribosomal protein S4, X-linked
chr2_-_14701903 5.46 ENSRNOT00000051895
Cox7c
cytochrome c oxidase subunit 7C
chr6_-_25211494 5.39 ENSRNOT00000009634
Xdh
xanthine dehydrogenase
chr4_-_163214678 5.13 ENSRNOT00000091602
Clec1a
C-type lectin domain family 1, member A
chr16_+_26859397 5.08 ENSRNOT00000044171
Msmo1
methylsterol monooxygenase 1
chr11_-_71284939 5.03 ENSRNOT00000002421
AABR07034428.1

chrX_-_75224268 4.59 ENSRNOT00000089809
Abcb7
ATP binding cassette subfamily B member 7
chr2_-_193184942 4.41 ENSRNOT00000032698
LOC686143
similar to keratinocytes proline-rich protein
chr2_+_60920257 4.14 ENSRNOT00000025170
C1qtnf3
C1q and tumor necrosis factor related protein 3
chr10_+_104523996 4.10 ENSRNOT00000065339
ENSRNOT00000086747
Itgb4
integrin subunit beta 4
chr19_-_12942943 4.01 ENSRNOT00000064105
ENSRNOT00000090886
Large1
LARGE xylosyl- and glucuronyltransferase 1
chr1_-_22661377 3.79 ENSRNOT00000021896
Vnn3
vanin 3
chr6_-_109205004 3.78 ENSRNOT00000010512
Tmed10
transmembrane p24 trafficking protein 10
chr11_+_43465370 3.74 ENSRNOT00000039939
Olr1547
olfactory receptor 1547
chr8_-_93390305 3.71 ENSRNOT00000056930
Ibtk
inhibitor of Bruton tyrosine kinase
chr4_-_71893306 3.54 ENSRNOT00000077710
Olr803
olfactory receptor 803
chr2_+_193429176 3.28 ENSRNOT00000011762
Crnn
cornulin
chr2_-_61692487 3.16 ENSRNOT00000078544
LOC499541
LRRGT00045
chr10_-_98018014 3.16 ENSRNOT00000005367
Fam20a
FAM20A, golgi associated secretory pathway pseudokinase
chr11_-_80826505 3.10 ENSRNOT00000032383
Rtp1
receptor (chemosensory) transporter protein 1
chr17_+_47397558 3.06 ENSRNOT00000085923
Epdr1
ependymin related 1
chr2_+_233602732 3.05 ENSRNOT00000044232
Pitx2
paired-like homeodomain 2
chr1_-_168177139 2.87 ENSRNOT00000075135
Olr72
olfactory receptor 72
chr17_-_21705773 2.84 ENSRNOT00000078010
Gcnt2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
chr19_-_38796 2.75 ENSRNOT00000077592
AABR07042565.1

chr3_+_75712483 2.59 ENSRNOT00000049264
Olr575
olfactory receptor 575
chr11_-_29710849 2.56 ENSRNOT00000029345
Krtap11-1
keratin associated protein 11-1
chr5_-_2803855 2.54 ENSRNOT00000009490
LOC297756
ribosomal protein S8-like
chr6_-_106971250 2.54 ENSRNOT00000010926
Dpf3
double PHD fingers 3
chr3_-_103217528 2.52 ENSRNOT00000074456
Olr784
olfactory receptor 784
chr5_-_102743417 2.51 ENSRNOT00000067389
Bnc2
basonuclin 2
chr11_+_43476319 2.46 ENSRNOT00000044928
Olr1548
olfactory receptor 1548
chr1_-_103323476 2.29 ENSRNOT00000019051
Mrgprx3
MAS related GPR family member X3
chr17_-_51912496 2.28 ENSRNOT00000019272
Inhba
inhibin beta A subunit
chr6_-_115769793 2.20 ENSRNOT00000039910
AABR07065217.2

chr1_-_82279145 2.17 ENSRNOT00000057433
Cxcl17
C-X-C motif chemokine ligand 17
chr10_-_87335823 2.13 ENSRNOT00000079297
Krt12
keratin 12
chr6_+_147315328 2.13 ENSRNOT00000056654
Macc1
MACC1, MET transcriptional regulator
chr1_-_215033460 2.10 ENSRNOT00000044565
Dusp8
dual specificity phosphatase 8
chr12_-_35318685 2.08 ENSRNOT00000074199
AABR07036167.1

chr1_+_170147300 1.99 ENSRNOT00000048075
Olr200
olfactory receptor 200
chr5_-_59198650 1.99 ENSRNOT00000020958
Olr833
olfactory receptor 833
chr10_-_94488180 1.98 ENSRNOT00000015818
Gh1
growth hormone 1
chr1_+_168244888 1.94 ENSRNOT00000021102
Olr79
olfactory receptor 79
chr13_+_91711995 1.94 ENSRNOT00000040596
Olr1582
olfactory receptor 1582
chr9_+_81559605 1.92 ENSRNOT00000089698
Gpbar1
G protein-coupled bile acid receptor 1
chr4_+_166958466 1.92 ENSRNOT00000007538
Tas2r13
taste receptor, type 2, member 13
chr13_-_50497466 1.91 ENSRNOT00000076072
Etnk2
ethanolamine kinase 2
chr1_+_263968134 1.73 ENSRNOT00000018090
LOC681458
similar to stearoyl-coenzyme A desaturase 3
chr7_-_92996025 1.59 ENSRNOT00000076327
Samd12
sterile alpha motif domain containing 12
chr7_+_16394354 1.55 ENSRNOT00000041157
Olr1058
olfactory receptor 1058
chr2_-_192381716 1.52 ENSRNOT00000064950
AABR07012291.1

chr13_-_62524556 1.49 ENSRNOT00000033201
AABR07021239.1

chr1_+_169683311 1.48 ENSRNOT00000075826
Olr162
olfactory receptor 162
chr7_+_141642777 1.40 ENSRNOT00000079811
AABR07058884.2

chr10_-_78690857 1.37 ENSRNOT00000089255
LOC303448
similar to glyceraldehyde-3-phosphate dehydrogenase
chr2_+_187322416 1.36 ENSRNOT00000025183
Crabp2
cellular retinoic acid binding protein 2
chr10_-_43512287 1.34 ENSRNOT00000036481
Faxdc2
fatty acid hydroxylase domain containing 2
chr2_+_192553983 1.31 ENSRNOT00000085204
LOC102550416
small proline-rich protein 2I-like
chr3_-_74868575 1.30 ENSRNOT00000051625
Olr544
olfactory receptor 544
chrX_+_10811478 1.28 ENSRNOT00000060930
LOC307727
similar to Probable chromodomain-helicase-DNA-binding protein KIAA1416
chr14_-_45376127 1.20 ENSRNOT00000059247
AABR07015015.2

chr14_+_7618022 1.09 ENSRNOT00000088508
ENSRNOT00000002819
Slc10a6
solute carrier family 10 member 6
chr7_+_2459141 1.01 ENSRNOT00000075681
Naca
nascent polypeptide-associated complex alpha subunit
chr7_+_18120715 1.01 ENSRNOT00000068151
Vom1r108
vomeronasal 1 receptor 108
chr4_-_144318580 1.00 ENSRNOT00000007591
Ssuh2
ssu-2 homolog
chr10_+_10875983 0.99 ENSRNOT00000052265
LOC679823
similar to 60S ribosomal protein L37a
chr14_+_107268128 0.96 ENSRNOT00000012224
Tmem17
transmembrane protein 17
chr3_-_134696654 0.96 ENSRNOT00000006454
Flrt3
fibronectin leucine rich transmembrane protein 3
chr6_-_21135880 0.90 ENSRNOT00000051239
Rasgrp3
RAS guanyl releasing protein 3
chr2_+_192604978 0.84 ENSRNOT00000084784
LOC102550416
small proline-rich protein 2I-like
chr1_+_264094080 0.83 ENSRNOT00000047602
ENSRNOT00000017834
Scd4
stearoyl-coenzyme A desaturase 4
chr19_-_15733412 0.80 ENSRNOT00000014831
Irx6
iroquois homeobox 6
chr7_-_122926336 0.80 ENSRNOT00000000205
Chadl
chondroadherin-like
chr14_+_72889038 0.75 ENSRNOT00000084261
Rab5a
RAB5A, member RAS oncogene family
chr3_-_77911561 0.70 ENSRNOT00000084947
Olr679
olfactory receptor 679
chr3_+_75582317 0.70 ENSRNOT00000079367
Olr569
olfactory receptor 569
chr11_+_43340505 0.68 ENSRNOT00000043299
Olr1541
olfactory receptor 1541
chrX_+_23416395 0.64 ENSRNOT00000089821
AABR07037545.1

chr1_+_168411463 0.44 ENSRNOT00000072397
Olr89
olfactory receptor 89
chr1_+_67660337 0.39 ENSRNOT00000046111
LOC102551504
vomeronasal type-1 receptor 4-like
chr1_-_266428239 0.38 ENSRNOT00000027160
Cyp17a1
cytochrome P450, family 17, subfamily a, polypeptide 1
chr14_-_13058172 0.36 ENSRNOT00000002746
ENSRNOT00000071706
Prdm8
PR/SET domain 8
chr14_+_22597103 0.35 ENSRNOT00000048482
Ugt2a1
UDP glucuronosyltransferase 2 family, polypeptide A1
chr1_-_168082740 0.35 ENSRNOT00000070789
LOC684376
similar to olfactory receptor 555
chrX_+_71324365 0.31 ENSRNOT00000004911
Nono
non-POU domain containing, octamer-binding
chr6_-_77421286 0.27 ENSRNOT00000011453
Nkx2-1
NK2 homeobox 1
chr1_+_169074475 0.21 ENSRNOT00000050248
Olr132
olfactory receptor 132
chr1_-_168501212 0.21 ENSRNOT00000014730
Olr97
olfactory receptor 97
chr1_+_84067938 0.20 ENSRNOT00000057213
Numbl
NUMB-like, endocytic adaptor protein
chr1_+_80256973 0.18 ENSRNOT00000024113
Ercc1
ERCC excision repair 1, endonuclease non-catalytic subunit
chr8_+_119214541 0.15 ENSRNOT00000050117
RGD1564138
similar to 60S ribosomal protein L29 (P23)
chr11_+_85030872 0.12 ENSRNOT00000074815
LOC100911043
olfactory receptor 2L3-like
chr7_+_18068060 0.11 ENSRNOT00000065474
Vom1r107
vomeronasal 1 receptor 107
chr17_+_21600432 0.11 ENSRNOT00000060340
RGD1562963
similar to chromosome 6 open reading frame 52

Network of associatons between targets according to the STRING database.

First level regulatory network of Nfix

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
11.2 33.7 GO:0006480 N-terminal protein amino acid methylation(GO:0006480)
9.4 28.1 GO:0034445 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445) multicellular organism lipid catabolic process(GO:0044240)
6.9 27.8 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
6.6 26.4 GO:0046351 disaccharide biosynthetic process(GO:0046351)
6.3 37.9 GO:0044004 killing by symbiont of host cells(GO:0001907) disruption by symbiont of host cell(GO:0044004) response to platinum ion(GO:0070541)
6.1 79.9 GO:0001778 plasma membrane repair(GO:0001778)
6.1 24.3 GO:0014028 notochord formation(GO:0014028)
5.0 20.0 GO:1990375 baculum development(GO:1990375)
4.5 22.5 GO:0002003 angiotensin maturation(GO:0002003)
4.5 22.4 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
3.6 10.8 GO:0034971 histone H3-R17 methylation(GO:0034971)
2.5 10.1 GO:0003219 cardiac right ventricle formation(GO:0003219)
2.4 9.7 GO:1902730 positive regulation of proteoglycan biosynthetic process(GO:1902730)
2.4 9.4 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
2.1 6.3 GO:2001205 negative regulation of osteoclast development(GO:2001205)
1.6 18.1 GO:0043587 tongue morphogenesis(GO:0043587)
1.5 10.7 GO:1900019 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
1.5 3.1 GO:0035993 deltoid tuberosity development(GO:0035993)
1.3 12.7 GO:0060346 bone trabecula formation(GO:0060346)
1.3 3.8 GO:0035964 COPI-coated vesicle budding(GO:0035964)
1.2 56.3 GO:0030199 collagen fibril organization(GO:0030199)
1.2 5.8 GO:1904640 response to methionine(GO:1904640)
1.1 5.4 GO:0009115 xanthine catabolic process(GO:0009115)
1.0 6.9 GO:0097105 presynaptic membrane assembly(GO:0097105)
1.0 1.9 GO:0038183 bile acid signaling pathway(GO:0038183)
0.8 4.1 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.8 15.4 GO:0060134 prepulse inhibition(GO:0060134)
0.7 2.0 GO:0071469 cellular response to alkaline pH(GO:0071469)
0.6 2.6 GO:1903964 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.6 15.5 GO:0010866 regulation of triglyceride biosynthetic process(GO:0010866)
0.6 4.1 GO:0035878 nail development(GO:0035878)
0.6 2.3 GO:0060279 positive regulation of ovulation(GO:0060279)
0.6 2.8 GO:0036438 maintenance of lens transparency(GO:0036438)
0.5 10.7 GO:0043586 tongue development(GO:0043586)
0.5 5.5 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.4 11.0 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.4 7.4 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.3 1.0 GO:1901227 negative regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901227)
0.3 11.1 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.3 13.0 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.3 4.0 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.2 0.7 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.2 2.1 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.2 7.0 GO:0031639 plasminogen activation(GO:0031639)
0.2 10.4 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.2 3.2 GO:0070166 enamel mineralization(GO:0070166)
0.2 2.2 GO:0010759 positive regulation of macrophage chemotaxis(GO:0010759)
0.2 12.0 GO:0046889 positive regulation of lipid biosynthetic process(GO:0046889)
0.1 3.7 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.1 7.5 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.1 3.1 GO:0051205 protein insertion into membrane(GO:0051205)
0.1 1.9 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1 5.1 GO:0016126 sterol biosynthetic process(GO:0016126)
0.1 3.8 GO:0006767 water-soluble vitamin metabolic process(GO:0006767)
0.1 1.4 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.1 4.6 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.1 15.4 GO:0055001 muscle cell development(GO:0055001)
0.1 2.1 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.1 0.8 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.1 0.2 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.1 0.3 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.1 0.2 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720) nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.1 2.5 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.1 7.8 GO:0050680 negative regulation of epithelial cell proliferation(GO:0050680)
0.1 0.3 GO:0060510 forebrain dorsal/ventral pattern formation(GO:0021798) Clara cell differentiation(GO:0060486) Type II pneumocyte differentiation(GO:0060510)
0.0 5.8 GO:0045727 positive regulation of translation(GO:0045727)
0.0 0.4 GO:0021540 corpus callosum morphogenesis(GO:0021540)
0.0 0.4 GO:0019585 uronic acid metabolic process(GO:0006063) glucuronate metabolic process(GO:0019585) cellular glucuronidation(GO:0052695)
0.0 7.0 GO:0006814 sodium ion transport(GO:0006814)
0.0 1.8 GO:0050909 sensory perception of taste(GO:0050909)
0.0 3.1 GO:0007160 cell-matrix adhesion(GO:0007160)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
8.9 79.9 GO:0005826 actomyosin contractile ring(GO:0005826)
4.6 18.5 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
3.2 19.1 GO:0016012 sarcoglycan complex(GO:0016012)
2.6 31.8 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
2.2 28.1 GO:0042627 chylomicron(GO:0042627)
2.0 20.0 GO:0097550 transcriptional preinitiation complex(GO:0097550)
1.8 23.0 GO:0031983 vesicle lumen(GO:0031983)
0.8 12.6 GO:0071565 nBAF complex(GO:0071565)
0.8 2.3 GO:0043511 inhibin complex(GO:0043511)
0.7 9.3 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.7 12.0 GO:0042589 zymogen granule membrane(GO:0042589)
0.5 5.9 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.5 35.5 GO:0045095 keratin filament(GO:0045095)
0.4 2.0 GO:0070195 growth hormone receptor complex(GO:0070195)
0.3 10.8 GO:0005719 nuclear euchromatin(GO:0005719)
0.3 16.4 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.3 5.5 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.3 38.9 GO:0005604 basement membrane(GO:0005604)
0.3 10.3 GO:0046930 pore complex(GO:0046930)
0.2 11.2 GO:0031225 anchored component of membrane(GO:0031225)
0.2 26.4 GO:0030018 Z disc(GO:0030018)
0.2 11.7 GO:0005811 lipid particle(GO:0005811)
0.1 52.8 GO:0031012 extracellular matrix(GO:0031012)
0.1 4.1 GO:0005581 collagen trimer(GO:0005581)
0.1 5.4 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.1 11.0 GO:0016605 PML body(GO:0016605)
0.1 23.8 GO:0016607 nuclear speck(GO:0016607)
0.1 0.2 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.1 1.0 GO:0036038 MKS complex(GO:0036038)
0.1 0.9 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 2.5 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 6.3 GO:0005923 bicellular tight junction(GO:0005923)
0.0 2.1 GO:0005882 intermediate filament(GO:0005882)
0.0 16.0 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0 8.3 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 8.3 GO:0005911 cell-cell junction(GO:0005911)
0.0 6.6 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 10.2 GO:0005615 extracellular space(GO:0005615)
0.0 3.3 GO:0005667 transcription factor complex(GO:0005667)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
11.2 33.7 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
4.0 28.1 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
4.0 20.0 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798)
3.2 12.7 GO:0038181 bile acid receptor activity(GO:0038181)
2.7 8.0 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
2.0 37.9 GO:0015643 toxic substance binding(GO:0015643)
1.5 34.2 GO:0070006 metalloaminopeptidase activity(GO:0070006)
1.5 26.4 GO:0050308 sugar-phosphatase activity(GO:0050308)
1.1 5.4 GO:0016726 xanthine dehydrogenase activity(GO:0004854) oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor(GO:0016726)
1.1 7.4 GO:0035375 zymogen binding(GO:0035375)
0.8 4.1 GO:0038132 neuregulin binding(GO:0038132)
0.7 22.7 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.7 2.8 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.6 2.6 GO:0032896 palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.6 3.1 GO:0031849 olfactory receptor binding(GO:0031849)
0.6 24.3 GO:0046875 ephrin receptor binding(GO:0046875)
0.6 2.3 GO:0070699 type II activin receptor binding(GO:0070699)
0.5 3.7 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.5 9.3 GO:0017166 vinculin binding(GO:0017166)
0.5 10.1 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.4 10.3 GO:0015288 porin activity(GO:0015288)
0.4 10.7 GO:0005112 Notch binding(GO:0005112)
0.4 11.1 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.4 2.0 GO:0005131 growth hormone receptor binding(GO:0005131)
0.4 1.9 GO:0004103 choline kinase activity(GO:0004103)
0.3 22.2 GO:0005518 collagen binding(GO:0005518)
0.2 12.7 GO:0005504 fatty acid binding(GO:0005504)
0.2 6.8 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.2 5.5 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.2 73.0 GO:0003779 actin binding(GO:0003779)
0.1 5.1 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.1 9.4 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 2.1 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 14.0 GO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191)
0.1 1.4 GO:0019841 retinol binding(GO:0019841)
0.1 3.2 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 12.7 GO:0008201 heparin binding(GO:0008201)
0.1 5.8 GO:0019843 rRNA binding(GO:0019843)
0.1 0.7 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021)
0.1 6.9 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 1.5 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.4 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 1.4 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620)
0.0 4.6 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0 4.5 GO:0008237 metallopeptidase activity(GO:0008237)
0.0 0.4 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.0 13.4 GO:0005198 structural molecule activity(GO:0005198)
0.0 1.0 GO:0051082 unfolded protein binding(GO:0051082)
0.0 3.5 GO:0030246 carbohydrate binding(GO:0030246)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 4.1 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
1.7 85.7 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.8 24.3 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.7 38.2 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.5 23.2 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.5 20.0 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.3 71.5 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.3 7.0 PID NETRIN PATHWAY Netrin-mediated signaling events
0.3 10.8 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.2 8.0 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.2 9.4 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.2 10.1 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 3.1 SIG CHEMOTAXIS Genes related to chemotaxis
0.1 2.3 PID ALK1 PATHWAY ALK1 signaling events
0.1 3.7 PID BCR 5PATHWAY BCR signaling pathway
0.0 7.7 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.9 PID RAS PATHWAY Regulation of Ras family activation
0.0 11.1 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.7 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.3 PID CIRCADIAN PATHWAY Circadian rhythm pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
3.8 37.9 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
1.6 22.4 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
1.0 18.7 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.9 34.4 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.5 5.4 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.4 22.0 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.4 10.1 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.3 7.0 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.2 9.3 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.2 2.3 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.2 5.1 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.2 9.4 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.2 6.3 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 1.9 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 5.8 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 11.7 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF
0.1 5.5 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 4.1 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.4 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 1.9 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 0.9 REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)