ISMARA results: Klf12_Klf14

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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Klf12_Klf14_Sp4

Z-value: 1.36

Motif logo

Transcription factors associated with Klf12_Klf14_Sp4

Gene Symbol	Gene ID	Gene Info
Klf12 NCBI RGD Ensembl	ENSRNOG00000009145	Kruppel-like factor 12
Klf14 NCBI RGD Ensembl	ENSRNOG00000027557	Kruppel-like factor 14
Sp4 NCBI RGD Ensembl	ENSRNOG00000005472	Sp4 transcription factor

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Klf12	rn6_v1_chr15_-_84676125_84676125	-0.47	1.2e-18	Click!
Klf14	rn6_v1_chr4_-_58250798_58250798	-0.20	3.9e-04	Click!
Sp4	rn6_v1_chr6_-_146195819_146195819	-0.04	5.1e-01	Click!

Activity profile of Klf12_Klf14_Sp4 motif

Sorted Z-values of Klf12_Klf14_Sp4 motif

Top targets:

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr12_+_12227010 Show fit	60.79	ENSRNOT00000060843 ENSRNOT00000092610	Baiap2l1 NCBI RGD Ensembl Show fit	BAI1-associated protein 2-like 1
chr2_+_77868412 Show fit	49.85	ENSRNOT00000065897 ENSRNOT00000014022	Myo10 NCBI RGD Ensembl Show fit	myosin X
chr1_+_103172987 Show fit	38.62	ENSRNOT00000018688	Tmem86a NCBI RGD Ensembl Show fit	transmembrane protein 86A
chr1_-_80544825 Show fit	37.40	ENSRNOT00000057802 ENSRNOT00000040060 ENSRNOT00000067049 ENSRNOT00000052387 ENSRNOT00000073352	Relb NCBI RGD Ensembl Show fit	RELB proto-oncogene, NF-kB subunit
chr3_-_14538241 Show fit	37.04	ENSRNOT00000025904	Stom NCBI RGD Ensembl Show fit	stomatin
chr20_+_13799102 Show fit	35.53	ENSRNOT00000001669	Gstt1 NCBI RGD Ensembl Show fit	glutathione S-transferase theta 1
chr12_+_2180150 Show fit	31.68	ENSRNOT00000001322	Stxbp2 NCBI RGD Ensembl Show fit	syntaxin binding protein 2
chr1_-_142615673 Show fit	30.80	ENSRNOT00000018021	Iqgap1 NCBI RGD Ensembl Show fit	IQ motif containing GTPase activating protein 1
chr8_+_5967463 Show fit	30.46	ENSRNOT00000086251	Tmem123 NCBI RGD Ensembl Show fit	transmembrane protein 123
chr19_-_37370429 Show fit	29.05	ENSRNOT00000022497	Kctd19 NCBI RGD Ensembl Show fit	potassium channel tetramerization domain containing 19
chr1_-_78212350 Show fit	28.67	ENSRNOT00000071098	Inafm1 NCBI RGD Ensembl Show fit	InaF-motif containing 1
chr15_+_40937708 Show fit	28.53	ENSRNOT00000018407	Spata13 NCBI RGD Ensembl Show fit	spermatogenesis associated 13
chr10_-_40525008 Show fit	27.91	ENSRNOT00000016440	Slc36a2 NCBI RGD Ensembl Show fit	solute carrier family 36 member 2
chr13_+_34610684 Show fit	27.17	ENSRNOT00000093019 ENSRNOT00000003280	Tfcp2l1 NCBI RGD Ensembl Show fit	transcription factor CP2-like 1
chr20_-_3397039 Show fit	26.50	ENSRNOT00000001084 ENSRNOT00000085259	Ppp1r18 NCBI RGD Ensembl Show fit	protein phosphatase 1, regulatory subunit 18
chr5_+_155812105 Show fit	26.32	ENSRNOT00000039341	AABR07073181.1 NCBI RGD Ensembl Show fit
chr14_-_1461543 Show fit	25.82	ENSRNOT00000075656	Crlf2 NCBI RGD Ensembl Show fit	cytokine receptor-like factor 2
chr10_-_105600913 Show fit	24.69	ENSRNOT00000068026	Rhbdf2 NCBI RGD Ensembl Show fit	rhomboid 5 homolog 2
chr12_+_16988136 Show fit	24.55	ENSRNOT00000078925 ENSRNOT00000036744	Micall2 NCBI RGD Ensembl Show fit	MICAL-like 2
chr16_+_48863418 Show fit	24.23	ENSRNOT00000029868	Primpol NCBI RGD Ensembl Show fit	primase and DNA directed polymerase
chr9_-_78369031 Show fit	24.00	ENSRNOT00000087870	Bard1 NCBI RGD Ensembl Show fit	BRCA1 associated RING domain 1
chr1_+_256745288 Show fit	23.36	ENSRNOT00000022133	Cep55 NCBI RGD Ensembl Show fit	centrosomal protein 55
chr14_-_84662143 Show fit	23.21	ENSRNOT00000057529 ENSRNOT00000080078	Hormad2 NCBI RGD Ensembl Show fit	HORMA domain containing 2
chr1_+_142034423 Show fit	21.43	ENSRNOT00000090006	Ttll13 NCBI RGD Ensembl Show fit	tubulin tyrosine ligase-like family, member 13
chr4_-_81968832 Show fit	21.04	ENSRNOT00000016608	Skap2 NCBI RGD Ensembl Show fit	src kinase associated phosphoprotein 2
chr16_+_74752655 Show fit	20.85	ENSRNOT00000029266	Ckap2 NCBI RGD Ensembl Show fit	cytoskeleton associated protein 2
chr12_-_18540166 Show fit	20.84	ENSRNOT00000001792	Il3ra NCBI RGD Ensembl Show fit	interleukin 3 receptor subunit alpha
chr5_-_57168610 Show fit	20.60	ENSRNOT00000090499	B4galt1 NCBI RGD Ensembl Show fit	beta-1,4-galactosyltransferase 1
chr4_+_79021872 Show fit	20.34	ENSRNOT00000012677 ENSRNOT00000067125	Fam221a NCBI RGD Ensembl Show fit	family with sequence similarity 221, member A
chr5_-_76756140 Show fit	20.19	ENSRNOT00000022107 ENSRNOT00000089251	Ptbp3 NCBI RGD Ensembl Show fit	polypyrimidine tract binding protein 3
chr1_-_47213749 Show fit	19.99	ENSRNOT00000024656	Dynlt1 NCBI RGD Ensembl Show fit	dynein light chain Tctex-type 1
chr13_+_49092306 Show fit	19.65	ENSRNOT00000000039	Nuak2 NCBI RGD Ensembl Show fit	NUAK family kinase 2
chr1_+_85162452 Show fit	19.28	ENSRNOT00000093347	Pak4 NCBI RGD Ensembl Show fit	p21 (RAC1) activated kinase 4
chr1_-_87221826 Show fit	19.15	ENSRNOT00000046611 ENSRNOT00000028006	Spint2 NCBI RGD Ensembl Show fit	serine peptidase inhibitor, Kunitz type, 2
chr9_+_112293388 Show fit	19.12	ENSRNOT00000020767	Man2a1 NCBI RGD Ensembl Show fit	mannosidase, alpha, class 2A, member 1
chr2_-_112831476 Show fit	18.55	ENSRNOT00000018055	Ect2 NCBI RGD Ensembl Show fit	epithelial cell transforming 2
chr3_-_3890758 Show fit	18.39	ENSRNOT00000064083	Sec16a NCBI RGD Ensembl Show fit	SEC16 homolog A, endoplasmic reticulum export factor
chr12_+_40244081 Show fit	18.37	ENSRNOT00000030583	Sh2b3 NCBI RGD Ensembl Show fit	SH2B adaptor protein 3
chr1_-_89329185 Show fit	18.31	ENSRNOT00000078284	Cd22 NCBI RGD Ensembl Show fit	CD22 molecule
chr7_-_23594133 Show fit	17.91	ENSRNOT00000005746	Timp3 NCBI RGD Ensembl Show fit	TIMP metallopeptidase inhibitor 3
chr1_-_89329418 Show fit	17.81	ENSRNOT00000033155	Cd22 NCBI RGD Ensembl Show fit	CD22 molecule
chr19_+_38039729 Show fit	17.66	ENSRNOT00000089783	Nfatc3 NCBI RGD Ensembl Show fit	nuclear factor of activated T-cells 3
chr9_-_78368777 Show fit	17.65	ENSRNOT00000020414	Bard1 NCBI RGD Ensembl Show fit	BRCA1 associated RING domain 1
chr2_+_165601007 Show fit	17.30	ENSRNOT00000013931	Smc4 NCBI RGD Ensembl Show fit	structural maintenance of chromosomes 4
chr8_-_22874637 Show fit	16.82	ENSRNOT00000064551 ENSRNOT00000090424	Dock6 NCBI RGD Ensembl Show fit	dedicator of cytokinesis 6
chr1_+_167309051 Show fit	16.79	ENSRNOT00000055235 ENSRNOT00000076894	Pgap2 NCBI RGD Ensembl Show fit	post-GPI attachment to proteins 2
chr8_-_22821397 Show fit	16.54	ENSRNOT00000045488	Kank2 NCBI RGD Ensembl Show fit	KN motif and ankyrin repeat domains 2
chr1_-_82266727 Show fit	16.44	ENSRNOT00000027910	Lipe NCBI RGD Ensembl Show fit	lipase E, hormone sensitive type
chr4_-_56493923 Show fit	16.41	ENSRNOT00000027173	Impdh1 NCBI RGD Ensembl Show fit	inosine monophosphate dehydrogenase 1
chr12_-_16934706 Show fit	16.35	ENSRNOT00000001720	Mafk NCBI RGD Ensembl Show fit	MAF bZIP transcription factor K
chr19_+_15195565 Show fit	16.30	ENSRNOT00000090865 ENSRNOT00000078874	Ces1d NCBI RGD Ensembl Show fit	carboxylesterase 1D
chr1_+_221448661 Show fit	16.10	ENSRNOT00000072493	LOC100910252 NCBI RGD Ensembl Show fit	sororin-like
chr7_-_12673659 Show fit	16.08	ENSRNOT00000091650 ENSRNOT00000041277 ENSRNOT00000044865	Ptbp1 NCBI RGD Ensembl Show fit	polypyrimidine tract binding protein 1
chr3_+_170354141 Show fit	15.73	ENSRNOT00000005901	Fam210b NCBI RGD Ensembl Show fit	family with sequence similarity 210, member B
chr19_+_38039564 Show fit	15.73	ENSRNOT00000087491	Nfatc3 NCBI RGD Ensembl Show fit	nuclear factor of activated T-cells 3
chr1_-_32140136 Show fit	15.64	ENSRNOT00000081339 ENSRNOT00000022635	Slc12a7 NCBI RGD Ensembl Show fit	solute carrier family 12 member 7
chr7_+_12043794 Show fit	15.64	ENSRNOT00000039813	Atp8b3 NCBI RGD Ensembl Show fit	ATPase phospholipid transporting 8B3
chr8_+_122789453 Show fit	15.59	ENSRNOT00000014585	Cmtm6 NCBI RGD Ensembl Show fit	CKLF-like MARVEL transmembrane domain containing 6
chr14_+_34727623 Show fit	15.34	ENSRNOT00000071405 ENSRNOT00000090183	Kdr NCBI RGD Ensembl Show fit	kinase insert domain receptor
chr10_+_106812739 Show fit	15.33	ENSRNOT00000074225	Syngr2 NCBI RGD Ensembl Show fit	synaptogyrin 2
chr1_+_31967978 Show fit	15.28	ENSRNOT00000081471 ENSRNOT00000021532	Trip13 NCBI RGD Ensembl Show fit	thyroid hormone receptor interactor 13
chr3_-_47025128 Show fit	15.24	ENSRNOT00000011682	Rbms1 NCBI RGD Ensembl Show fit	RNA binding motif, single stranded interacting protein 1
chr20_-_45260119 Show fit	15.22	ENSRNOT00000000718	Slc16a10 NCBI RGD Ensembl Show fit	solute carrier family 16 member 10
chr2_-_202816562 Show fit	15.21	ENSRNOT00000020401	Fam46c NCBI RGD Ensembl Show fit	family with sequence similarity 46, member C
chr4_+_157612536 Show fit	15.19	ENSRNOT00000055970	Chd4 NCBI RGD Ensembl Show fit	chromodomain helicase DNA binding protein 4
chr5_-_33182147 Show fit	15.06	ENSRNOT00000080358	Maged2 NCBI RGD Ensembl Show fit	MAGE family member D2
chr1_-_221041401 Show fit	15.04	ENSRNOT00000064136	Pcnx3 NCBI RGD Ensembl Show fit	pecanex homolog 3 (Drosophila)
chr14_-_7384876 Show fit	15.02	ENSRNOT00000086694	Aff1 NCBI RGD Ensembl Show fit	AF4/FMR2 family, member 1
chr8_+_62341613 Show fit	14.94	ENSRNOT00000066923	Scamp2 NCBI RGD Ensembl Show fit	secretory carrier membrane protein 2
chr17_-_43614844 Show fit	14.93	ENSRNOT00000023054	Hist1h1a NCBI RGD Ensembl Show fit	histone cluster 1 H1 family member a
chr9_-_27192135 Show fit	14.91	ENSRNOT00000017592	Tram2 NCBI RGD Ensembl Show fit	translocation associated membrane protein 2
chr4_-_123713319 Show fit	14.84	ENSRNOT00000012875 ENSRNOT00000086982	Slc6a6 NCBI RGD Ensembl Show fit	solute carrier family 6 member 6
chr16_+_20426566 Show fit	14.77	ENSRNOT00000026225	Ifi30 NCBI RGD Ensembl Show fit	IFI30, lysosomal thiol reductase
chr1_+_199655660 Show fit	14.76	ENSRNOT00000027032	Armc5 NCBI RGD Ensembl Show fit	armadillo repeat containing 5
chr14_+_34727915 Show fit	14.65	ENSRNOT00000085089	Kdr NCBI RGD Ensembl Show fit	kinase insert domain receptor
chr2_+_122877286 Show fit	14.52	ENSRNOT00000033080	Arse NCBI RGD Ensembl Show fit	arylsulfatase E
chr19_+_26106838 Show fit	14.50	ENSRNOT00000035987	Hook2 NCBI RGD Ensembl Show fit	hook microtubule-tethering protein 2
chr1_+_263367266 Show fit	14.45	ENSRNOT00000054714	Nkx2-3 NCBI RGD Ensembl Show fit	NK2 homeobox 3
chr1_+_78710539 Show fit	14.38	ENSRNOT00000021455	Slc1a5 NCBI RGD Ensembl Show fit	solute carrier family 1 member 5
chr3_-_2136936 Show fit	14.28	ENSRNOT00000010169	Arrdc1 NCBI RGD Ensembl Show fit	arrestin domain containing 1
chr5_+_105230580 Show fit	14.28	ENSRNOT00000010056	Acer2 NCBI RGD Ensembl Show fit	alkaline ceramidase 2
chr1_+_31835000 Show fit	14.23	ENSRNOT00000020780	Cep72 NCBI RGD Ensembl Show fit	centrosomal protein 72
chr3_-_160802433 Show fit	14.13	ENSRNOT00000076191	Slpi NCBI RGD Ensembl Show fit	secretory leukocyte peptidase inhibitor
chr13_-_95943761 Show fit	13.92	ENSRNOT00000005961	Adss NCBI RGD Ensembl Show fit	adenylosuccinate synthase
chr5_-_107857320 Show fit	13.72	ENSRNOT00000008898	Cdkn2b NCBI RGD Ensembl Show fit	cyclin-dependent kinase inhibitor 2B
chr7_-_3132457 Show fit	13.45	ENSRNOT00000031963	Cdk2 NCBI RGD Ensembl Show fit	cyclin dependent kinase 2
chr15_-_51839341 Show fit	13.45	ENSRNOT00000011277	RGD1308117 NCBI RGD Ensembl Show fit	similar to 9930012K11Rik protein
chr3_-_119611136 Show fit	13.41	ENSRNOT00000016157	Ncaph NCBI RGD Ensembl Show fit	non-SMC condensin I complex, subunit H
chr1_+_218632764 Show fit	13.14	ENSRNOT00000019861	Tesmin NCBI RGD Ensembl Show fit	testis expressed metallothionein like protein
chr5_-_151824633 Show fit	12.94	ENSRNOT00000043959	Sfn NCBI RGD Ensembl Show fit	stratifin
chr6_+_43829945 Show fit	12.85	ENSRNOT00000086548	Klf11 NCBI RGD Ensembl Show fit	Kruppel-like factor 11
chr1_-_19376301 Show fit	12.78	ENSRNOT00000015547	Arhgap18 NCBI RGD Ensembl Show fit	Rho GTPase activating protein 18
chr20_-_45259928 Show fit	12.75	ENSRNOT00000087226	Slc16a10 NCBI RGD Ensembl Show fit	solute carrier family 16 member 10
chr1_+_85324079 Show fit	12.72	ENSRNOT00000093693	Samd4b NCBI RGD Ensembl Show fit	sterile alpha motif domain containing 4B
chr1_-_80666566 Show fit	12.51	ENSRNOT00000082125 ENSRNOT00000025388	Nectin2 NCBI RGD Ensembl Show fit	nectin cell adhesion molecule 2
chr10_+_89484468 Show fit	12.42	ENSRNOT00000035523	Tmem106a NCBI RGD Ensembl Show fit	transmembrane protein 106A
chr19_+_24456976 Show fit	12.37	ENSRNOT00000004900	Ucp1 NCBI RGD Ensembl Show fit	uncoupling protein 1
chr8_+_96564877 Show fit	12.28	ENSRNOT00000017879	Mthfs NCBI RGD Ensembl Show fit	5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
chr6_+_144291974 Show fit	12.15	ENSRNOT00000035255	Ncapg2 NCBI RGD Ensembl Show fit	non-SMC condensin II complex, subunit G2
chr1_+_214434626 Show fit	12.10	ENSRNOT00000025319	Pnpla2 NCBI RGD Ensembl Show fit	patatin-like phospholipase domain containing 2
chr11_-_30977483 Show fit	12.01	ENSRNOT00000002851	Urb1 NCBI RGD Ensembl Show fit	URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
chr8_-_22929294 Show fit	11.97	ENSRNOT00000015609	Rab3d NCBI RGD Ensembl Show fit	RAB3D, member RAS oncogene family
chr2_+_190073815 Show fit	11.94	ENSRNOT00000015473	S100a8 NCBI RGD Ensembl Show fit	S100 calcium binding protein A8
chr7_+_142912316 Show fit	11.86	ENSRNOT00000010171	Nr4a1 NCBI RGD Ensembl Show fit	nuclear receptor subfamily 4, group A, member 1
chr2_-_207300854 Show fit	11.82	ENSRNOT00000018061	Mov10 NCBI RGD Ensembl Show fit	Mov10 RISC complex RNA helicase
chr18_-_28454756 Show fit	11.81	ENSRNOT00000040091	Spata24 NCBI RGD Ensembl Show fit	spermatogenesis associated 24
chr5_+_145188323 Show fit	11.80	ENSRNOT00000038888	Tmem35b NCBI RGD Ensembl Show fit	transmembrane protein 35B
chr9_-_9702306 Show fit	11.77	ENSRNOT00000082341	Trip10 NCBI RGD Ensembl Show fit	thyroid hormone receptor interactor 10
chr9_+_20765296 Show fit	11.72	ENSRNOT00000016291	Cd2ap NCBI RGD Ensembl Show fit	CD2-associated protein
chr16_-_20890949 Show fit	11.69	ENSRNOT00000081977	Homer3 NCBI RGD Ensembl Show fit	homer scaffolding protein 3
chr10_-_56962161 Show fit	11.68	ENSRNOT00000026038	Alox15 NCBI RGD Ensembl Show fit	arachidonate 15-lipoxygenase
chr2_+_209097927 Show fit	11.66	ENSRNOT00000023807	Dennd2d NCBI RGD Ensembl Show fit	DENN domain containing 2D
chr1_+_213997709 Show fit	11.52	ENSRNOT00000025826	LOC100911615 NCBI RGD Ensembl Show fit	patatin-like phospholipase domain-containing protein 2-like
chr3_+_100366168 Show fit	11.45	ENSRNOT00000006689	Kif18a NCBI RGD Ensembl Show fit	kinesin family member 18A
chr12_+_38490230 Show fit	11.35	ENSRNOT00000047861	Diablo NCBI RGD Ensembl Show fit	diablo, IAP-binding mitochondrial protein
chr5_+_172986291 Show fit	11.28	ENSRNOT00000022900	Nadk NCBI RGD Ensembl Show fit	NAD kinase
chr3_+_164274710 Show fit	11.25	ENSRNOT00000012939	Snai1 NCBI RGD Ensembl Show fit	snail family transcriptional repressor 1
chr5_+_139468546 Show fit	11.22	ENSRNOT00000013193	Slfnl1 NCBI RGD Ensembl Show fit	schlafen-like 1
chr1_+_166893734 Show fit	11.20	ENSRNOT00000026702	Phox2a NCBI RGD Ensembl Show fit	paired-like homeobox 2a
chr20_-_49486550 Show fit	11.11	ENSRNOT00000048270 ENSRNOT00000076541	Prdm1 NCBI RGD Ensembl Show fit	PR/SET domain 1
chr8_+_22937916 Show fit	11.06	ENSRNOT00000088255 ENSRNOT00000049993	Ccdc159 NCBI RGD Ensembl Show fit	coiled-coil domain containing 159
chr8_+_118206698 Show fit	11.03	ENSRNOT00000082607 ENSRNOT00000064140	Smarcc1 NCBI RGD Ensembl Show fit	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
chr15_-_11912806 Show fit	10.99	ENSRNOT00000068171 ENSRNOT00000008759 ENSRNOT00000049771	Slc4a7 NCBI RGD Ensembl Show fit	solute carrier family 4 member 7
chr12_+_51948650 Show fit	10.91	ENSRNOT00000056735	Ep400 NCBI RGD Ensembl Show fit	E1A binding protein p400
chr3_+_150323116 Show fit	10.89	ENSRNOT00000023429 ENSRNOT00000080485	Raly NCBI RGD Ensembl Show fit	RALY heterogeneous nuclear ribonucleoprotein
chr2_-_116161998 Show fit	10.77	ENSRNOT00000012560	Gpr160 NCBI RGD Ensembl Show fit	G protein-coupled receptor 160
chr15_+_33108671 Show fit	10.77	ENSRNOT00000015468	Lrp10 NCBI RGD Ensembl Show fit	LDL receptor related protein 10
chr19_-_52499433 Show fit	10.72	ENSRNOT00000021954	Cotl1 NCBI RGD Ensembl Show fit	coactosin-like F-actin binding protein 1
chr11_+_87204175 Show fit	10.69	ENSRNOT00000000306	Slc25a1 NCBI RGD Ensembl Show fit	solute carrier family 25 member 1
chr12_+_22165486 Show fit	10.69	ENSRNOT00000001890	Mospd3 NCBI RGD Ensembl Show fit	motile sperm domain containing 3
chr8_-_22821223 Show fit	10.69	ENSRNOT00000014135	Kank2 NCBI RGD Ensembl Show fit	KN motif and ankyrin repeat domains 2
chr19_-_9931930 Show fit	10.68	ENSRNOT00000085144	Ccdc113 NCBI RGD Ensembl Show fit	coiled-coil domain containing 113
chr4_-_147893992 Show fit	10.67	ENSRNOT00000032158	Plxnd1 NCBI RGD Ensembl Show fit	plexin D1
chr3_-_160738927 Show fit	10.64	ENSRNOT00000043470	Slpil2 NCBI RGD Ensembl Show fit	antileukoproteinase-like 2
chr10_-_37645802 Show fit	10.60	ENSRNOT00000008022	Tcf7 NCBI RGD Ensembl Show fit	transcription factor 7 (T-cell specific, HMG-box)
chr7_+_120206188 Show fit	10.54	ENSRNOT00000086853	Triobp NCBI RGD Ensembl Show fit	TRIO and F-actin binding protein
chr10_-_88442796 Show fit	10.52	ENSRNOT00000077579 ENSRNOT00000023447 ENSRNOT00000043172	Acly NCBI RGD Ensembl Show fit	ATP citrate lyase
chr12_-_11265865 Show fit	10.50	ENSRNOT00000001315	Arpc1b NCBI RGD Ensembl Show fit	actin related protein 2/3 complex, subunit 1B
chr1_+_84280945 Show fit	10.50	ENSRNOT00000057190	Sertad3 NCBI RGD Ensembl Show fit	SERTA domain containing 3
chr12_-_24046814 Show fit	10.43	ENSRNOT00000001961	Por NCBI RGD Ensembl Show fit	cytochrome p450 oxidoreductase
chr10_+_56576428 Show fit	10.42	ENSRNOT00000079237 ENSRNOT00000023291	Cldn7 NCBI RGD Ensembl Show fit	claudin 7
chr1_-_87155118 Show fit	10.37	ENSRNOT00000072441	AABR07002854.1 NCBI RGD Ensembl Show fit
chr1_-_256734719 Show fit	10.37	ENSRNOT00000021546 ENSRNOT00000089456	Myof NCBI RGD Ensembl Show fit	myoferlin
chr19_-_19509087 Show fit	10.34	ENSRNOT00000019301	Nkd1 NCBI RGD Ensembl Show fit	naked cuticle homolog 1
chr20_-_31598118 Show fit	10.24	ENSRNOT00000046537	Col13a1 NCBI RGD Ensembl Show fit	collagen type XIII alpha 1 chain
chr7_-_2941122 Show fit	10.17	ENSRNOT00000082107	Esyt1 NCBI RGD Ensembl Show fit	extended synaptotagmin 1
chr14_+_79343499 Show fit	10.12	ENSRNOT00000077846	Tbc1d14 NCBI RGD Ensembl Show fit	TBC1 domain family, member 14
chr8_-_48564722 Show fit	10.05	ENSRNOT00000067902	Cbl NCBI RGD Ensembl Show fit	Cbl proto-oncogene
chr3_-_160730360 Show fit	10.05	ENSRNOT00000075864	RGD1563818 NCBI RGD Ensembl Show fit	similar to secretory leukocyte protease inhibitor
chr15_+_83442144 Show fit	10.03	ENSRNOT00000039344	Bora NCBI RGD Ensembl Show fit	bora, aurora kinase A activator
chr16_-_21362955 Show fit	10.02	ENSRNOT00000039607	Gmip NCBI RGD Ensembl Show fit	Gem-interacting protein
chr1_-_65551043 Show fit	10.00	ENSRNOT00000029996	Trim28 NCBI RGD Ensembl Show fit	tripartite motif-containing 28
chr18_-_70184337 Show fit	10.00	ENSRNOT00000020637	Ska1 NCBI RGD Ensembl Show fit	spindle and kinetochore associated complex subunit 1
chr2_-_183031214 Show fit	9.94	ENSRNOT00000013260	LOC679811 NCBI RGD Ensembl Show fit	similar to RIKEN cDNA D930015E06
chr10_-_61744976 Show fit	9.91	ENSRNOT00000079926 ENSRNOT00000092314 ENSRNOT00000034298	Sgsm2 NCBI RGD Ensembl Show fit	small G protein signaling modulator 2
chr16_-_20592449 Show fit	9.86	ENSRNOT00000026821	Isyna1 NCBI RGD Ensembl Show fit	inositol-3-phosphate synthase 1
chr20_-_22004209 Show fit	9.85	ENSRNOT00000086250 ENSRNOT00000068778	Rtkn2 NCBI RGD Ensembl Show fit	rhotekin 2
chr3_+_112531703 Show fit	9.85	ENSRNOT00000041727	LOC100911204 NCBI RGD Ensembl Show fit	protein CASC5-like
chr1_+_266053002 Show fit	9.84	ENSRNOT00000026235	Nfkb2 NCBI RGD Ensembl Show fit	nuclear factor kappa B subunit 2
chr7_+_12144162 Show fit	9.80	ENSRNOT00000077122	Tcf3 NCBI RGD Ensembl Show fit	transcription factor 3
chr15_+_3436361 Show fit	9.80	ENSRNOT00000016387	Ap3m1 NCBI RGD Ensembl Show fit	adaptor-related protein complex 3, mu 1 subunit
chr7_+_12006710 Show fit	9.79	ENSRNOT00000045421	Klf16 NCBI RGD Ensembl Show fit	Kruppel-like factor 16
chr16_-_19942343 Show fit	9.77	ENSRNOT00000087162 ENSRNOT00000091906	Bst2 NCBI RGD Ensembl Show fit	bone marrow stromal cell antigen 2
chr5_-_62260089 Show fit	9.73	ENSRNOT00000064858 ENSRNOT00000011714	Tbc1d2 NCBI RGD Ensembl Show fit	TBC1 domain family, member 2
chr15_-_34269851 Show fit	9.71	ENSRNOT00000026279	Psme2 NCBI RGD Ensembl Show fit	proteasome activator subunit 2
chr4_+_7661558 Show fit	9.71	ENSRNOT00000080229	Fam126a NCBI RGD Ensembl Show fit	family with sequence similarity 126, member A
chr13_-_83457888 Show fit	9.70	ENSRNOT00000076289 ENSRNOT00000004065	Sft2d2 NCBI RGD Ensembl Show fit	SFT2 domain containing 2
chr3_-_63507926 Show fit	9.66	ENSRNOT00000015624	Prkra NCBI RGD Ensembl Show fit	protein activator of interferon induced protein kinase EIF2AK2
chr3_-_138116664 Show fit	9.63	ENSRNOT00000055602	Rrbp1 NCBI RGD Ensembl Show fit	ribosome binding protein 1
chr6_-_125723732 Show fit	9.60	ENSRNOT00000084815	Fbln5 NCBI RGD Ensembl Show fit	fibulin 5
chr10_+_61772449 Show fit	9.59	ENSRNOT00000004058	Smg6 NCBI RGD Ensembl Show fit	SMG6 nonsense mediated mRNA decay factor
chr3_-_160739137 Show fit	9.59	ENSRNOT00000075836	Slpil2 NCBI RGD Ensembl Show fit	antileukoproteinase-like 2
chr2_+_178389799 Show fit	9.56	ENSRNOT00000013356	RGD1560010 NCBI RGD Ensembl Show fit	RGD1560010
chr5_-_160555083 Show fit	9.45	ENSRNOT00000018953	Fhad1 NCBI RGD Ensembl Show fit	forkhead associated phosphopeptide binding domain 1
chr18_-_63488027 Show fit	9.41	ENSRNOT00000023763	Ptpn2 NCBI RGD Ensembl Show fit	protein tyrosine phosphatase, non-receptor type 2
chr13_+_52976507 Show fit	9.37	ENSRNOT00000090599 ENSRNOT00000011324	Kif21b NCBI RGD Ensembl Show fit	kinesin family member 21B
chr19_+_58746313 Show fit	9.34	ENSRNOT00000026986	Map3k21 NCBI RGD Ensembl Show fit	mitogen-activated protein kinase kinase kinase 21
chr10_+_105500290 Show fit	9.30	ENSRNOT00000079080 ENSRNOT00000083593	Sphk1 NCBI RGD Ensembl Show fit	sphingosine kinase 1
chr14_+_37919233 Show fit	9.29	ENSRNOT00000003125	Tec NCBI RGD Ensembl Show fit	tec protein tyrosine kinase
chr20_-_4896970 Show fit	9.20	ENSRNOT00000061114 ENSRNOT00000060980	RT1-CE7 NCBI RGD Ensembl Show fit RT1-CE5 NCBI RGD Ensembl Show fit	RT1 class I, locus CE7 RT1 class I, locus CE5
chr1_-_163129641 Show fit	9.20	ENSRNOT00000083055	Capn5 NCBI RGD Ensembl Show fit	calpain 5
chr8_+_117737387 Show fit	9.16	ENSRNOT00000090164 ENSRNOT00000091573	Pfkfb4 NCBI RGD Ensembl Show fit	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
chr14_-_7863664 Show fit	9.12	ENSRNOT00000061162	Ptpn13 NCBI RGD Ensembl Show fit	protein tyrosine phosphatase, non-receptor type 13
chr4_-_123510217 Show fit	9.12	ENSRNOT00000080734	Slc41a3 NCBI RGD Ensembl Show fit	solute carrier family 41, member 3
chr7_+_114724610 Show fit	9.08	ENSRNOT00000014541	Dennd3 NCBI RGD Ensembl Show fit	DENN domain containing 3
chr9_+_14551758 Show fit	9.07	ENSRNOT00000017157	Nfya NCBI RGD Ensembl Show fit	nuclear transcription factor Y subunit alpha
chr7_-_14189688 Show fit	9.07	ENSRNOT00000037456	Notch3 NCBI RGD Ensembl Show fit	notch 3
chr8_+_116311078 Show fit	9.05	ENSRNOT00000037363	Rassf1 NCBI RGD Ensembl Show fit	Ras association domain family member 1
chr5_-_136002900 Show fit	9.05	ENSRNOT00000025197	Plk3 NCBI RGD Ensembl Show fit	polo-like kinase 3
chr3_-_164095878 Show fit	9.01	ENSRNOT00000079414	B4galt5 NCBI RGD Ensembl Show fit	beta-1,4-galactosyltransferase 5
chr20_+_4355175 Show fit	9.01	ENSRNOT00000000510	Gpsm3 NCBI RGD Ensembl Show fit	G-protein signaling modulator 3
chr19_+_49457677 Show fit	8.99	ENSRNOT00000084445	Cenpn NCBI RGD Ensembl Show fit	centromere protein N
chr1_+_220009397 Show fit	8.98	ENSRNOT00000084410	Rbm4b NCBI RGD Ensembl Show fit	RNA binding motif protein 4B
chr6_+_43884678 Show fit	8.97	ENSRNOT00000091551	Rrm2 NCBI RGD Ensembl Show fit	ribonucleotide reductase regulatory subunit M2
chr7_+_144014173 Show fit	8.94	ENSRNOT00000019403	Sp1 NCBI RGD Ensembl Show fit	Sp1 transcription factor
chr10_+_94280703 Show fit	8.92	ENSRNOT00000088656	Map3k3 NCBI RGD Ensembl Show fit	mitogen activated protein kinase kinase kinase 3
chr3_-_82368357 Show fit	8.91	ENSRNOT00000000052	Cd82 NCBI RGD Ensembl Show fit	Cd82 molecule
chr10_-_65507581 Show fit	8.88	ENSRNOT00000016759	Supt6h NCBI RGD Ensembl Show fit	SPT6 homolog, histone chaperone
chr5_-_143120165 Show fit	8.87	ENSRNOT00000012314	Zc3h12a NCBI RGD Ensembl Show fit	zinc finger CCCH type containing 12A
chr1_-_80689171 Show fit	8.83	ENSRNOT00000045574	Bcam NCBI RGD Ensembl Show fit	basal cell adhesion molecule (Lutheran blood group)

Network of associatons between targets according to the STRING database.

First level regulatory network of Klf12_Klf14_Sp4

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
11.8	35.5	GO:0042196	response to salicylic acid(GO:0009751) chlorinated hydrocarbon metabolic process(GO:0042196) halogenated hydrocarbon metabolic process(GO:0042197)
9.1	27.2	GO:0070563	negative regulation of vitamin D receptor signaling pathway(GO:0070563)
8.6	25.8	GO:0002380	immunoglobulin secretion involved in immune response(GO:0002380)
7.7	23.1	GO:0019626	short-chain fatty acid catabolic process(GO:0019626)
7.0	21.1	GO:0031439	positive regulation of mRNA cleavage(GO:0031439) positive regulation of endoribonuclease activity(GO:1902380) positive regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904722)
6.8	27.1	GO:0019060	intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
6.6	33.2	GO:0010032	meiotic chromosome condensation(GO:0010032)
6.6	26.5	GO:0060800	regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
6.1	36.5	GO:1900086	positive regulation of peptidyl-tyrosine autophosphorylation(GO:1900086)
6.0	6.0	GO:0015744	succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422)
5.7	34.2	GO:0048597	post-embryonic camera-type eye morphogenesis(GO:0048597)
5.6	28.0	GO:0015801	aromatic amino acid transport(GO:0015801)
5.6	27.9	GO:0010958	regulation of amino acid import(GO:0010958) glycine import(GO:0036233)
5.5	16.4	GO:0046340	diacylglycerol catabolic process(GO:0046340)
5.3	26.7	GO:1902339	apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
5.1	20.3	GO:0060671	epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
4.8	19.2	GO:0010424	DNA methylation on cytosine within a CG sequence(GO:0010424)
4.8	14.3	GO:0090283	regulation of protein glycosylation in Golgi(GO:0090283)
4.7	14.2	GO:1902211	regulation of prolactin signaling pathway(GO:1902211)
4.6	69.1	GO:0051764	actin crosslink formation(GO:0051764)
4.5	13.5	GO:0032298	positive regulation of DNA-dependent DNA replication initiation(GO:0032298)
4.5	17.9	GO:1903984	positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
4.3	8.5	GO:0001998	angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001998)
4.2	16.9	GO:1901187	regulation of ephrin receptor signaling pathway(GO:1901187)
4.2	12.7	GO:1905073	occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075)
4.2	46.1	GO:0085020	protein K6-linked ubiquitination(GO:0085020)
4.2	12.5	GO:0060370	susceptibility to T cell mediated cytotoxicity(GO:0060370)
3.8	11.4	GO:0003192	mitral valve formation(GO:0003192)
3.7	11.2	GO:0021558	trochlear nerve development(GO:0021558)
3.7	11.2	GO:0042560	folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
3.6	39.9	GO:0044829	positive regulation by host of viral genome replication(GO:0044829)
3.6	10.8	GO:0038158	granulocyte colony-stimulating factor signaling pathway(GO:0038158)
3.5	7.1	GO:1901873	regulation of post-translational protein modification(GO:1901873)
3.5	10.6	GO:0006529	asparagine biosynthetic process(GO:0006529)
3.5	17.6	GO:0002317	plasma cell differentiation(GO:0002317)
3.5	10.4	GO:0000294	nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294)
3.4	24.0	GO:0036016	response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
3.3	10.0	GO:0090309	positive regulation of methylation-dependent chromatin silencing(GO:0090309)
3.3	9.9	GO:0098749	cerebellar neuron development(GO:0098749)
3.3	6.6	GO:2000645	negative regulation of receptor catabolic process(GO:2000645)
3.3	9.9	GO:0034499	late endosome to Golgi transport(GO:0034499)
3.3	16.4	GO:0006177	GMP biosynthetic process(GO:0006177)
3.3	9.8	GO:0002731	negative regulation of dendritic cell cytokine production(GO:0002731)
3.2	9.7	GO:0044208	'de novo' AMP biosynthetic process(GO:0044208)
3.2	12.7	GO:0071640	regulation of macrophage inflammatory protein 1 alpha production(GO:0071640)
3.2	9.5	GO:0071929	alpha-tubulin acetylation(GO:0071929)
3.1	9.4	GO:1904154	positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
3.1	6.3	GO:1904674	positive regulation of somatic stem cell population maintenance(GO:1904674)
3.1	24.9	GO:0010891	negative regulation of sequestering of triglyceride(GO:0010891)
3.0	18.3	GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
3.0	24.2	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
3.0	8.9	GO:0070814	hydrogen sulfide biosynthetic process(GO:0070814)
2.9	11.7	GO:0032911	negative regulation of transforming growth factor beta1 production(GO:0032911)
2.9	49.0	GO:1902894	negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
2.9	5.7	GO:0070889	platelet alpha granule organization(GO:0070889)
2.9	20.1	GO:0007144	female meiosis I(GO:0007144)
2.9	2.9	GO:0045626	negative regulation of T-helper 1 cell differentiation(GO:0045626)
2.8	11.3	GO:0006741	NADP biosynthetic process(GO:0006741)
2.8	8.4	GO:0033566	gamma-tubulin complex localization(GO:0033566)
2.8	8.4	GO:0043316	cytotoxic T cell degranulation(GO:0043316)
2.8	2.8	GO:0060486	Clara cell differentiation(GO:0060486)
2.8	8.4	GO:0006667	sphinganine metabolic process(GO:0006667)
2.8	8.4	GO:0071348	cellular response to interleukin-11(GO:0071348)
2.8	8.3	GO:0046601	positive regulation of centriole replication(GO:0046601)
2.8	11.1	GO:0003419	growth plate cartilage chondrocyte proliferation(GO:0003419)
2.8	25.0	GO:0051177	meiotic sister chromatid segregation(GO:0045144) meiotic sister chromatid cohesion(GO:0051177)
2.7	13.6	GO:0038031	non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
2.7	10.8	GO:0030422	production of siRNA involved in RNA interference(GO:0030422)
2.7	10.7	GO:0015746	citrate transport(GO:0015746)
2.7	8.0	GO:0018201	peptidyl-glycine modification(GO:0018201)
2.7	10.6	GO:0048319	axial mesoderm morphogenesis(GO:0048319)
2.6	10.6	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
2.6	39.5	GO:0032688	negative regulation of interferon-beta production(GO:0032688)
2.6	15.7	GO:0070966	nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
2.6	10.3	GO:0097680	double-strand break repair via classical nonhomologous end joining(GO:0097680)
2.6	15.4	GO:0008635	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
2.5	17.8	GO:0061086	negative regulation of histone H3-K27 methylation(GO:0061086)
2.5	10.1	GO:0071955	recycling endosome to Golgi transport(GO:0071955)
2.5	15.1	GO:0070294	renal sodium ion absorption(GO:0070294)
2.5	19.9	GO:0006021	inositol biosynthetic process(GO:0006021)
2.4	12.2	GO:0021747	cochlear nucleus development(GO:0021747)
2.4	4.9	GO:0044837	assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
2.4	7.2	GO:0060084	synaptic transmission involved in micturition(GO:0060084)
2.4	2.4	GO:0003383	apical constriction(GO:0003383)
2.4	11.9	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
2.4	11.9	GO:0045590	negative regulation of regulatory T cell differentiation(GO:0045590)
2.4	11.8	GO:0098795	mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
2.3	7.0	GO:0061198	fungiform papilla formation(GO:0061198)
2.3	2.3	GO:1904585	response to putrescine(GO:1904585) cellular response to putrescine(GO:1904586)
2.3	30.2	GO:0043312	neutrophil degranulation(GO:0043312)
2.3	16.1	GO:0046512	sphingosine biosynthetic process(GO:0046512)
2.3	6.8	GO:0016480	negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
2.3	11.4	GO:0051122	hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
2.3	6.8	GO:1902463	protein localization to cell leading edge(GO:1902463)
2.3	25.0	GO:0043249	erythrocyte maturation(GO:0043249)
2.3	11.3	GO:0001923	B-1 B cell differentiation(GO:0001923)
2.3	6.8	GO:2000777	positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
2.2	15.7	GO:0045048	protein insertion into ER membrane(GO:0045048)
2.2	6.7	GO:0061314	Notch signaling involved in heart development(GO:0061314) endocardial cushion cell differentiation(GO:0061443)
2.2	6.6	GO:1900740	regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740) protein localization to vacuolar membrane(GO:1903778)
2.2	6.5	GO:0018364	peptidyl-glutamine methylation(GO:0018364)
2.2	12.9	GO:0010481	epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
2.1	2.1	GO:1901656	glycoside transport(GO:1901656)
2.1	8.4	GO:0018125	peptidyl-cysteine methylation(GO:0018125)
2.1	4.2	GO:0046104	thymidine metabolic process(GO:0046104)
2.1	8.2	GO:0046985	positive regulation of hemoglobin biosynthetic process(GO:0046985)
2.1	14.4	GO:0006868	glutamine transport(GO:0006868)
2.0	10.2	GO:0033088	negative regulation of immature T cell proliferation in thymus(GO:0033088)
2.0	2.0	GO:0045210	FasL biosynthetic process(GO:0045210)
2.0	6.1	GO:1902525	regulation of protein monoubiquitination(GO:1902525)
2.0	6.0	GO:1902202	regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
2.0	6.0	GO:0000973	posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
2.0	7.9	GO:1901030	positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901030)
2.0	7.9	GO:0072429	response to intra-S DNA damage checkpoint signaling(GO:0072429)
2.0	11.9	GO:0043435	response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
2.0	2.0	GO:0030423	targeting of mRNA for destruction involved in RNA interference(GO:0030423) siRNA loading onto RISC involved in RNA interference(GO:0035087)
1.9	7.8	GO:0035938	estrogen secretion(GO:0035937) estradiol secretion(GO:0035938) regulation of estrogen secretion(GO:2000861) regulation of estradiol secretion(GO:2000864)
1.9	5.8	GO:0072237	distal tubule morphogenesis(GO:0072156) metanephric proximal tubule development(GO:0072237)
1.9	7.7	GO:0032485	regulation of Ral protein signal transduction(GO:0032485)
1.9	3.8	GO:0060982	cardiac right ventricle formation(GO:0003219) coronary artery morphogenesis(GO:0060982)
1.9	5.7	GO:0002432	granuloma formation(GO:0002432)
1.9	22.8	GO:0007028	cytoplasm organization(GO:0007028)
1.9	13.2	GO:0002326	B cell lineage commitment(GO:0002326)
1.9	5.6	GO:0071630	nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
1.9	5.6	GO:0000189	MAPK import into nucleus(GO:0000189)
1.9	5.6	GO:0046947	hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
1.9	5.6	GO:0009098	branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
1.8	12.9	GO:2000271	positive regulation of fibroblast apoptotic process(GO:2000271)
1.8	9.2	GO:0060014	granulosa cell differentiation(GO:0060014)
1.8	7.4	GO:2000301	negative regulation of synaptic vesicle exocytosis(GO:2000301)
1.8	16.5	GO:0048207	vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
1.8	5.5	GO:1902534	single-organism membrane invagination(GO:1902534)
1.8	18.1	GO:0048251	elastic fiber assembly(GO:0048251)
1.8	25.3	GO:0051988	regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
1.8	1.8	GO:0019072	viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
1.8	10.7	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
1.8	7.1	GO:0003176	aortic valve development(GO:0003176) aortic valve morphogenesis(GO:0003180)
1.8	7.0	GO:0033277	abortive mitotic cell cycle(GO:0033277)
1.7	8.7	GO:0060454	positive regulation of gastric acid secretion(GO:0060454)
1.7	5.2	GO:0021997	neural plate axis specification(GO:0021997)
1.7	5.2	GO:0030174	regulation of DNA-dependent DNA replication initiation(GO:0030174)
1.7	1.7	GO:1901258	positive regulation of granulocyte colony-stimulating factor production(GO:0071657) positive regulation of macrophage colony-stimulating factor production(GO:1901258)
1.7	10.0	GO:0072103	glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104)
1.7	6.6	GO:0034729	histone H3-K79 methylation(GO:0034729)
1.7	5.0	GO:0038108	negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
1.6	8.2	GO:0071499	cellular response to laminar fluid shear stress(GO:0071499)
1.6	6.5	GO:2000048	negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
1.6	1.6	GO:0030908	intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
1.6	4.8	GO:2000275	regulation of oxidative phosphorylation uncoupler activity(GO:2000275)
1.6	9.6	GO:1904354	negative regulation of telomere capping(GO:1904354)
1.6	6.3	GO:1901423	response to benzene(GO:1901423)
1.6	11.0	GO:0071284	cellular response to lead ion(GO:0071284)
1.6	6.3	GO:0051142	regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
1.5	4.6	GO:0051088	PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
1.5	4.6	GO:0060821	inactivation of X chromosome by DNA methylation(GO:0060821)
1.5	6.2	GO:1904580	regulation of intracellular mRNA localization(GO:1904580)
1.5	21.6	GO:0006517	protein deglycosylation(GO:0006517)
1.5	18.4	GO:0006337	nucleosome disassembly(GO:0006337)
1.5	13.8	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
1.5	4.6	GO:1904528	positive regulation of microtubule binding(GO:1904528)
1.5	3.0	GO:2000286	receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
1.5	6.1	GO:1904587	response to glycoprotein(GO:1904587)
1.5	4.5	GO:0038163	thrombopoietin-mediated signaling pathway(GO:0038163)
1.5	38.7	GO:0044253	positive regulation of multicellular organismal metabolic process(GO:0044253)
1.5	5.9	GO:0038089	positive regulation of cell migration by vascular endothelial growth factor signaling pathway(GO:0038089)
1.5	2.9	GO:0010847	regulation of chromatin assembly(GO:0010847)
1.4	7.2	GO:0071681	cellular response to indole-3-methanol(GO:0071681)
1.4	18.7	GO:0070935	3'-UTR-mediated mRNA stabilization(GO:0070935)
1.4	4.3	GO:1904373	response to kainic acid(GO:1904373)
1.4	4.2	GO:1904100	regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
1.4	4.2	GO:0032242	regulation of nucleoside transport(GO:0032242) positive regulation of necroptotic process(GO:0060545)
1.4	9.7	GO:0019896	axonal transport of mitochondrion(GO:0019896)
1.4	5.5	GO:2000562	negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
1.4	6.9	GO:2000773	negative regulation of cellular senescence(GO:2000773)
1.4	1.4	GO:0060051	negative regulation of protein glycosylation(GO:0060051)
1.4	10.9	GO:0001842	neural fold formation(GO:0001842)
1.4	2.7	GO:0010887	negative regulation of cholesterol storage(GO:0010887)
1.3	6.7	GO:0048549	positive regulation of pinocytosis(GO:0048549)
1.3	2.7	GO:0033313	meiotic cell cycle checkpoint(GO:0033313)
1.3	2.7	GO:1904925	positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
1.3	26.7	GO:0045793	positive regulation of cell size(GO:0045793)
1.3	13.0	GO:0007076	mitotic chromosome condensation(GO:0007076)
1.3	2.6	GO:0071733	transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
1.3	2.6	GO:0061073	ciliary body morphogenesis(GO:0061073)
1.3	6.4	GO:1904668	positive regulation of ubiquitin protein ligase activity(GO:1904668)
1.3	12.7	GO:0002467	germinal center formation(GO:0002467)
1.3	22.7	GO:0001833	inner cell mass cell proliferation(GO:0001833)
1.3	8.8	GO:0035469	determination of pancreatic left/right asymmetry(GO:0035469)
1.2	6.2	GO:0042758	long-chain fatty acid catabolic process(GO:0042758)
1.2	3.7	GO:0046833	positive regulation of nucleobase-containing compound transport(GO:0032241) positive regulation of RNA export from nucleus(GO:0046833)
1.2	7.4	GO:0042984	amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
1.2	3.7	GO:2001286	regulation of caveolin-mediated endocytosis(GO:2001286)
1.2	2.4	GO:0060282	positive regulation of oocyte development(GO:0060282)
1.2	47.2	GO:0000281	mitotic cytokinesis(GO:0000281)
1.2	3.6	GO:1903593	regulation of histamine secretion by mast cell(GO:1903593)
1.2	3.6	GO:1990823	response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
1.2	4.8	GO:0055099	response to high density lipoprotein particle(GO:0055099)
1.2	2.4	GO:0032776	DNA methylation on cytosine(GO:0032776)
1.2	3.6	GO:0035290	trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491)
1.2	4.7	GO:0007084	mitotic nuclear envelope reassembly(GO:0007084)
1.2	11.8	GO:0042538	hyperosmotic salinity response(GO:0042538)
1.2	7.0	GO:1902746	regulation of lens fiber cell differentiation(GO:1902746)
1.2	7.0	GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
1.2	8.1	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
1.2	5.8	GO:0072553	terminal button organization(GO:0072553)
1.2	3.5	GO:0090038	negative regulation of protein kinase C signaling(GO:0090038)
1.2	4.6	GO:2001199	negative regulation of dendritic cell differentiation(GO:2001199)
1.1	4.6	GO:0060744	thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
1.1	3.4	GO:0035655	interleukin-18-mediated signaling pathway(GO:0035655)
1.1	3.4	GO:1900169	regulation of glucocorticoid mediated signaling pathway(GO:1900169)
1.1	8.0	GO:0097327	response to antineoplastic agent(GO:0097327)
1.1	13.6	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
1.1	4.5	GO:0001922	B-1 B cell homeostasis(GO:0001922)
1.1	5.7	GO:1903300	negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
1.1	5.7	GO:0060903	positive regulation of meiosis I(GO:0060903)
1.1	7.9	GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
1.1	6.8	GO:2000622	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
1.1	1.1	GO:1903334	positive regulation of protein folding(GO:1903334)
1.1	2.2	GO:0035697	CD8-positive, alpha-beta T cell extravasation(GO:0035697) regulation of CD8-positive, alpha-beta T cell extravasation(GO:2000449)
1.1	2.2	GO:0089700	protein kinase D signaling(GO:0089700)
1.1	3.3	GO:2000523	regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
1.1	3.3	GO:0008588	release of cytoplasmic sequestered NF-kappaB(GO:0008588)
1.1	12.1	GO:0060253	negative regulation of glial cell proliferation(GO:0060253)
1.1	13.0	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
1.1	2.1	GO:0044340	canonical Wnt signaling pathway involved in regulation of cell proliferation(GO:0044340)
1.1	7.5	GO:0070836	caveola assembly(GO:0070836)
1.1	14.9	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
1.1	3.2	GO:1902304	positive regulation of potassium ion export(GO:1902304)
1.1	12.7	GO:0035970	peptidyl-threonine dephosphorylation(GO:0035970)
1.1	3.2	GO:0097010	eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
1.1	1.1	GO:0006449	regulation of translational termination(GO:0006449)
1.0	8.4	GO:0090286	cytoskeletal anchoring at nuclear membrane(GO:0090286)
1.0	2.1	GO:0035234	ectopic germ cell programmed cell death(GO:0035234)
1.0	4.1	GO:1900041	negative regulation of interleukin-2 secretion(GO:1900041)
1.0	2.0	GO:0007223	Wnt signaling pathway, calcium modulating pathway(GO:0007223)
1.0	11.2	GO:0046606	negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)
1.0	11.1	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
1.0	6.0	GO:0060334	regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
1.0	3.0	GO:0071907	determination of digestive tract left/right asymmetry(GO:0071907)
1.0	3.0	GO:0032986	protein-DNA complex disassembly(GO:0032986)
1.0	66.3	GO:0046847	filopodium assembly(GO:0046847)
1.0	34.0	GO:0007339	binding of sperm to zona pellucida(GO:0007339)
1.0	2.0	GO:1903385	regulation of homophilic cell adhesion(GO:1903385)
1.0	6.9	GO:0035338	long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
1.0	20.6	GO:0035162	embryonic hemopoiesis(GO:0035162)
1.0	2.9	GO:0031536	positive regulation of exit from mitosis(GO:0031536)
1.0	3.9	GO:1904996	positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
1.0	1.9	GO:0018171	peptidyl-cysteine oxidation(GO:0018171)
1.0	10.6	GO:0009313	oligosaccharide catabolic process(GO:0009313)
1.0	36.5	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
1.0	5.7	GO:2000096	positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.9	10.3	GO:0006107	oxaloacetate metabolic process(GO:0006107)
0.9	1.9	GO:0032762	mast cell cytokine production(GO:0032762) positive regulation of relaxation of muscle(GO:1901079)
0.9	7.5	GO:0070914	UV-damage excision repair(GO:0070914)
0.9	3.7	GO:0006369	termination of RNA polymerase II transcription(GO:0006369)
0.9	2.8	GO:0038128	ERBB2 signaling pathway(GO:0038128)
0.9	0.9	GO:0019521	aldonic acid metabolic process(GO:0019520) D-gluconate metabolic process(GO:0019521)
0.9	3.7	GO:0048861	leukemia inhibitory factor signaling pathway(GO:0048861)
0.9	2.7	GO:0030505	inorganic diphosphate transport(GO:0030505)
0.9	2.7	GO:0030043	actin filament fragmentation(GO:0030043)
0.9	3.6	GO:0048865	stem cell fate commitment(GO:0048865)
0.9	3.6	GO:2000304	positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.9	2.7	GO:0036451	cap mRNA methylation(GO:0036451)
0.9	9.9	GO:0045002	double-strand break repair via single-strand annealing(GO:0045002)
0.9	9.7	GO:0006527	arginine catabolic process(GO:0006527)
0.9	5.3	GO:0002433	immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096)
0.9	5.3	GO:0033031	positive regulation of neutrophil apoptotic process(GO:0033031)
0.9	1.7	GO:0042706	eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.9	3.4	GO:0045647	negative regulation of erythrocyte differentiation(GO:0045647)
0.9	4.3	GO:0045901	positive regulation of translational elongation(GO:0045901)
0.8	4.2	GO:0044791	modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.8	10.2	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.8	1.7	GO:0019372	lipoxygenase pathway(GO:0019372)
0.8	1.7	GO:0001828	inner cell mass cellular morphogenesis(GO:0001828)
0.8	2.5	GO:0048210	Golgi vesicle fusion to target membrane(GO:0048210)
0.8	10.8	GO:0060670	branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.8	10.7	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.8	3.3	GO:1901524	regulation of macromitophagy(GO:1901524)
0.8	3.2	GO:0060279	positive regulation of ovulation(GO:0060279)
0.8	1.6	GO:0021943	formation of radial glial scaffolds(GO:0021943)
0.8	18.4	GO:0019884	antigen processing and presentation of exogenous antigen(GO:0019884)
0.8	4.8	GO:0050861	positive regulation of B cell receptor signaling pathway(GO:0050861)
0.8	3.2	GO:0048368	lateral mesoderm development(GO:0048368)
0.8	4.8	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.8	4.8	GO:0015074	DNA integration(GO:0015074)
0.8	3.9	GO:0009052	pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.8	3.9	GO:1902036	regulation of hematopoietic stem cell differentiation(GO:1902036)
0.8	8.6	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.8	3.9	GO:0030952	establishment or maintenance of actin cytoskeleton polarity(GO:0030950) establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.8	2.3	GO:0097298	regulation of nucleus size(GO:0097298)
0.8	5.4	GO:0048563	post-embryonic organ morphogenesis(GO:0048563)
0.8	11.6	GO:0006851	mitochondrial calcium ion transport(GO:0006851)
0.8	2.3	GO:0019355	nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.8	3.0	GO:0070272	proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.8	4.5	GO:0030263	apoptotic chromosome condensation(GO:0030263)
0.8	3.8	GO:0051461	positive regulation of corticotropin secretion(GO:0051461)
0.8	2.3	GO:0021979	hypothalamus cell differentiation(GO:0021979)
0.7	7.5	GO:0016601	Rac protein signal transduction(GO:0016601)
0.7	2.2	GO:0044376	RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.7	9.7	GO:2001241	positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.7	0.7	GO:1902861	copper ion import across plasma membrane(GO:0098705) copper ion import into cell(GO:1902861)
0.7	4.4	GO:0072757	cellular response to camptothecin(GO:0072757)
0.7	2.2	GO:0006616	SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.7	12.5	GO:0043968	histone H2A acetylation(GO:0043968)
0.7	6.6	GO:0035608	protein deglutamylation(GO:0035608)
0.7	2.9	GO:2000830	vacuolar phosphate transport(GO:0007037) positive regulation of parathyroid hormone secretion(GO:2000830)
0.7	9.4	GO:1900017	positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.7	0.7	GO:0002589	regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589)
0.7	3.6	GO:1904401	cellular response to Thyroid stimulating hormone(GO:1904401)
0.7	14.4	GO:0060396	growth hormone receptor signaling pathway(GO:0060396)
0.7	1.4	GO:0045448	regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.7	1.4	GO:1904742	regulation of telomeric DNA binding(GO:1904742)
0.7	7.9	GO:0051085	chaperone mediated protein folding requiring cofactor(GO:0051085)
0.7	3.6	GO:0090168	Golgi reassembly(GO:0090168)
0.7	9.1	GO:0019511	peptidyl-proline hydroxylation(GO:0019511)
0.7	2.8	GO:0048133	germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.7	18.8	GO:0006335	DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.7	5.6	GO:0035330	regulation of hippo signaling(GO:0035330)
0.7	2.1	GO:0031204	posttranslational protein targeting to membrane, translocation(GO:0031204)
0.7	3.5	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.7	6.3	GO:0019852	L-ascorbic acid metabolic process(GO:0019852)
0.7	6.2	GO:0039532	negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway(GO:0039532)
0.7	1.4	GO:0043096	purine nucleobase salvage(GO:0043096)
0.7	1.4	GO:0060003	copper ion export(GO:0060003)
0.7	2.1	GO:1903416	response to glycoside(GO:1903416)
0.7	1.4	GO:0036353	histone H2A-K119 monoubiquitination(GO:0036353)
0.7	2.7	GO:1904751	positive regulation of protein localization to nucleolus(GO:1904751)
0.7	4.1	GO:0006776	vitamin A metabolic process(GO:0006776)
0.7	3.4	GO:0032506	cytokinetic process(GO:0032506)
0.7	2.0	GO:0006421	asparaginyl-tRNA aminoacylation(GO:0006421)
0.7	5.4	GO:0051571	positive regulation of histone H3-K4 methylation(GO:0051571)
0.7	9.4	GO:0032060	bleb assembly(GO:0032060)
0.7	10.7	GO:0050832	defense response to fungus(GO:0050832)
0.7	2.0	GO:1900103	positive regulation of endoplasmic reticulum unfolded protein response(GO:1900103)
0.7	2.7	GO:0045869	single stranded viral RNA replication via double stranded DNA intermediate(GO:0039692) regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091) negative regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045869)
0.7	2.7	GO:0051660	establishment of centrosome localization(GO:0051660)
0.7	10.7	GO:0048026	positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.7	2.0	GO:2000052	positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.7	2.7	GO:0033234	negative regulation of protein sumoylation(GO:0033234)
0.7	2.6	GO:0090118	receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118)
0.7	2.6	GO:0046951	ketone body biosynthetic process(GO:0046951)
0.6	1.9	GO:0034395	regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395)
0.6	7.1	GO:0006346	methylation-dependent chromatin silencing(GO:0006346)
0.6	1.3	GO:0045575	basophil activation(GO:0045575)
0.6	1.9	GO:0032907	transforming growth factor beta3 production(GO:0032907) regulation of transforming growth factor beta3 production(GO:0032910) positive regulation of transforming growth factor beta3 production(GO:0032916)
0.6	27.2	GO:0043297	apical junction assembly(GO:0043297)
0.6	6.9	GO:0043306	positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.6	3.1	GO:0072364	regulation of cellular ketone metabolic process by regulation of transcription from RNA polymerase II promoter(GO:0072364)
0.6	5.0	GO:0032464	positive regulation of protein homooligomerization(GO:0032464)
0.6	1.9	GO:0033385	geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.6	5.0	GO:0016576	histone dephosphorylation(GO:0016576)
0.6	3.7	GO:0033567	DNA replication, Okazaki fragment processing(GO:0033567)
0.6	34.1	GO:1901184	regulation of ERBB signaling pathway(GO:1901184)
0.6	1.9	GO:0070650	actin filament bundle distribution(GO:0070650)
0.6	0.6	GO:0060913	cardiac cell fate determination(GO:0060913)
0.6	1.8	GO:0071763	nuclear membrane organization(GO:0071763)
0.6	3.7	GO:0060020	Bergmann glial cell differentiation(GO:0060020)
0.6	1.8	GO:1903677	regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
0.6	3.6	GO:2000051	negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.6	10.9	GO:0072520	seminiferous tubule development(GO:0072520)
0.6	12.1	GO:0048255	mRNA stabilization(GO:0048255)
0.6	1.8	GO:0006931	substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.6	1.8	GO:0001983	baroreceptor response to increased systemic arterial blood pressure(GO:0001983)
0.6	16.8	GO:0019731	antibacterial humoral response(GO:0019731)
0.6	1.8	GO:0071586	CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
0.6	2.4	GO:0018158	protein oxidation(GO:0018158)
0.6	4.1	GO:1901223	negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.6	1.2	GO:0060754	positive regulation of mast cell chemotaxis(GO:0060754)
0.6	2.3	GO:0031937	positive regulation of chromatin silencing(GO:0031937)
0.6	1.8	GO:0001560	regulation of cell growth by extracellular stimulus(GO:0001560)
0.6	3.5	GO:0002315	marginal zone B cell differentiation(GO:0002315)
0.6	0.6	GO:0072361	regulation of glycolytic process by regulation of transcription from RNA polymerase II promoter(GO:0072361)
0.6	1.7	GO:0006436	tryptophanyl-tRNA aminoacylation(GO:0006436)
0.6	1.7	GO:0001698	gastrin-induced gastric acid secretion(GO:0001698) positive regulation of somatostatin secretion(GO:0090274)
0.6	1.2	GO:0030421	defecation(GO:0030421)
0.6	5.2	GO:0018026	peptidyl-lysine monomethylation(GO:0018026)
0.6	5.2	GO:0048304	positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.6	10.3	GO:0050779	RNA destabilization(GO:0050779)
0.6	10.3	GO:0006783	heme biosynthetic process(GO:0006783)
0.6	2.3	GO:0010764	negative regulation of fibroblast migration(GO:0010764)
0.6	3.9	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.6	1.7	GO:0035696	monocyte extravasation(GO:0035696)
0.6	6.1	GO:0046784	viral mRNA export from host cell nucleus(GO:0046784)
0.6	2.8	GO:0038203	TORC2 signaling(GO:0038203)
0.6	1.7	GO:0034124	regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
0.5	4.9	GO:0046643	regulation of gamma-delta T cell differentiation(GO:0045586) regulation of gamma-delta T cell activation(GO:0046643)
0.5	1.1	GO:0006933	negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.5	1.6	GO:0032218	riboflavin transport(GO:0032218)
0.5	2.2	GO:0007597	blood coagulation, intrinsic pathway(GO:0007597)
0.5	3.8	GO:0019856	'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.5	2.7	GO:0048496	maintenance of organ identity(GO:0048496)
0.5	1.6	GO:1901227	negative regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901227)
0.5	8.7	GO:0030947	regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030947)
0.5	3.2	GO:0050855	regulation of B cell receptor signaling pathway(GO:0050855)
0.5	13.5	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.5	3.8	GO:0010815	bradykinin catabolic process(GO:0010815)
0.5	15.0	GO:2000036	regulation of stem cell population maintenance(GO:2000036)
0.5	2.1	GO:0007039	protein catabolic process in the vacuole(GO:0007039)
0.5	1.1	GO:0070672	negative regulation of icosanoid secretion(GO:0032304) response to interleukin-15(GO:0070672)
0.5	8.5	GO:0038092	nodal signaling pathway(GO:0038092)
0.5	2.1	GO:0060586	multicellular organismal iron ion homeostasis(GO:0060586)
0.5	8.4	GO:0033962	cytoplasmic mRNA processing body assembly(GO:0033962)
0.5	9.5	GO:0006270	DNA replication initiation(GO:0006270)
0.5	4.2	GO:0009301	snRNA transcription(GO:0009301)
0.5	2.1	GO:2001028	positive regulation of endothelial cell chemotaxis(GO:2001028)
0.5	1.5	GO:0097069	cellular response to thyroxine stimulus(GO:0097069) cellular response to L-phenylalanine derivative(GO:1904387)
0.5	3.1	GO:0090073	positive regulation of protein homodimerization activity(GO:0090073)
0.5	8.2	GO:0007143	female meiotic division(GO:0007143)
0.5	11.2	GO:0034508	centromere complex assembly(GO:0034508)
0.5	2.0	GO:1902856	negative regulation of nonmotile primary cilium assembly(GO:1902856)
0.5	4.5	GO:0071493	cellular response to UV-B(GO:0071493)
0.5	5.5	GO:1900745	positive regulation of p38MAPK cascade(GO:1900745)
0.5	5.5	GO:1904262	negative regulation of TORC1 signaling(GO:1904262)
0.5	6.0	GO:1904030	negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.5	5.0	GO:0006265	DNA topological change(GO:0006265)
0.5	6.4	GO:2000188	regulation of cholesterol homeostasis(GO:2000188)
0.5	1.0	GO:0045653	negative regulation of megakaryocyte differentiation(GO:0045653)
0.5	3.4	GO:0006307	DNA dealkylation involved in DNA repair(GO:0006307)
0.5	1.5	GO:0043485	endosome to melanosome transport(GO:0035646) pigment accumulation(GO:0043476) cellular pigment accumulation(GO:0043482) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757)
0.5	2.4	GO:0071043	CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.5	2.9	GO:0034162	toll-like receptor 9 signaling pathway(GO:0034162)
0.5	9.7	GO:0050853	B cell receptor signaling pathway(GO:0050853)
0.5	11.6	GO:0045022	early endosome to late endosome transport(GO:0045022)
0.5	1.4	GO:0046061	dATP catabolic process(GO:0046061)
0.5	3.3	GO:0000012	single strand break repair(GO:0000012)
0.5	3.7	GO:2000780	negative regulation of double-strand break repair(GO:2000780)
0.5	2.3	GO:0033634	positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.5	1.9	GO:0072386	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.5	11.6	GO:0006884	cell volume homeostasis(GO:0006884)
0.5	1.4	GO:1904469	positive regulation of tumor necrosis factor secretion(GO:1904469)
0.5	2.3	GO:0031507	heterochromatin assembly(GO:0031507)
0.5	2.7	GO:0006477	protein sulfation(GO:0006477)
0.5	0.9	GO:0033523	histone H2B ubiquitination(GO:0033523)
0.5	2.3	GO:2000035	regulation of stem cell division(GO:2000035)
0.5	3.6	GO:1903232	melanosome assembly(GO:1903232)
0.5	2.7	GO:0016139	glycoside catabolic process(GO:0016139)
0.5	2.7	GO:0046836	glycolipid transport(GO:0046836)
0.5	2.7	GO:0010668	ectodermal cell differentiation(GO:0010668)
0.4	0.4	GO:0070370	cellular heat acclimation(GO:0070370)
0.4	11.2	GO:0036075	endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.4	1.3	GO:0080009	mRNA methylation(GO:0080009)
0.4	7.1	GO:0042832	defense response to protozoan(GO:0042832)
0.4	3.1	GO:0045086	positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.4	1.3	GO:1900109	regulation of histone H3-K9 dimethylation(GO:1900109) positive regulation of histone H3-K9 dimethylation(GO:1900111) positive regulation of histone H3-K9 trimethylation(GO:1900114)
0.4	3.5	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
0.4	1.3	GO:0003164	His-Purkinje system development(GO:0003164)
0.4	1.3	GO:1902269	positive regulation of polyamine transmembrane transport(GO:1902269)
0.4	2.2	GO:0002238	response to molecule of fungal origin(GO:0002238)
0.4	1.3	GO:0043987	histone H3-S10 phosphorylation(GO:0043987)
0.4	3.0	GO:0035518	histone H2A monoubiquitination(GO:0035518)
0.4	2.6	GO:0060218	hematopoietic stem cell differentiation(GO:0060218)
0.4	3.9	GO:0002446	neutrophil mediated immunity(GO:0002446)
0.4	1.7	GO:1904684	negative regulation of metalloendopeptidase activity(GO:1904684)
0.4	5.5	GO:0051352	negative regulation of ligase activity(GO:0051352) negative regulation of ubiquitin-protein transferase activity(GO:0051444)
0.4	3.0	GO:0042989	sequestering of actin monomers(GO:0042989)
0.4	5.1	GO:0046473	phosphatidic acid metabolic process(GO:0046473)
0.4	5.1	GO:0036120	response to platelet-derived growth factor(GO:0036119) cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.4	9.3	GO:0043551	regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.4	9.3	GO:0071470	cellular response to osmotic stress(GO:0071470)
0.4	8.8	GO:0007257	activation of JUN kinase activity(GO:0007257)
0.4	4.2	GO:0035721	intraciliary retrograde transport(GO:0035721)
0.4	18.0	GO:0045600	positive regulation of fat cell differentiation(GO:0045600)
0.4	4.6	GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
0.4	0.8	GO:1900368	regulation of RNA interference(GO:1900368)
0.4	15.4	GO:0010501	RNA secondary structure unwinding(GO:0010501)
0.4	1.6	GO:0072709	cellular response to sorbitol(GO:0072709)
0.4	7.8	GO:0016578	histone deubiquitination(GO:0016578)
0.4	1.6	GO:0072268	specification of loop of Henle identity(GO:0072086) pattern specification involved in metanephros development(GO:0072268)
0.4	7.4	GO:0060765	regulation of androgen receptor signaling pathway(GO:0060765)
0.4	1.6	GO:0071000	response to magnetism(GO:0071000)
0.4	2.4	GO:0072673	lamellipodium morphogenesis(GO:0072673)
0.4	2.0	GO:0071494	cellular response to UV-C(GO:0071494)
0.4	3.2	GO:1904294	positive regulation of ERAD pathway(GO:1904294)
0.4	0.8	GO:0030382	sperm mitochondrion organization(GO:0030382)
0.4	4.4	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.4	0.8	GO:2000325	regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
0.4	6.7	GO:0048490	anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.4	4.3	GO:0000076	DNA replication checkpoint(GO:0000076)
0.4	0.8	GO:1903181	regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181)
0.4	5.4	GO:1903393	positive regulation of adherens junction organization(GO:1903393)
0.4	5.0	GO:0007342	fusion of sperm to egg plasma membrane(GO:0007342)
0.4	1.9	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.4	2.7	GO:0015705	iodide transport(GO:0015705)
0.4	7.6	GO:0007099	centriole replication(GO:0007099)
0.4	4.2	GO:0061099	negative regulation of protein tyrosine kinase activity(GO:0061099)
0.4	3.0	GO:0006907	pinocytosis(GO:0006907)
0.4	11.7	GO:0042149	cellular response to glucose starvation(GO:0042149)
0.4	4.1	GO:0035385	Roundabout signaling pathway(GO:0035385)
0.4	0.4	GO:1902947	regulation of tau-protein kinase activity(GO:1902947)
0.4	2.6	GO:0072643	interferon-gamma secretion(GO:0072643)
0.4	0.7	GO:0048254	snoRNA localization(GO:0048254)
0.4	1.5	GO:0017187	peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.4	2.6	GO:1904491	protein localization to ciliary transition zone(GO:1904491)
0.4	1.1	GO:0043311	regulation of eosinophil degranulation(GO:0043309) positive regulation of eosinophil degranulation(GO:0043311) regulation of eosinophil activation(GO:1902566) positive regulation of eosinophil activation(GO:1902568)
0.4	0.7	GO:2000586	regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000586) negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.4	5.7	GO:0032274	gonadotropin secretion(GO:0032274)
0.4	1.1	GO:0019086	late viral transcription(GO:0019086)
0.4	2.1	GO:0010886	positive regulation of cholesterol storage(GO:0010886)
0.3	4.2	GO:0032836	glomerular basement membrane development(GO:0032836)
0.3	0.7	GO:0036123	histone H3-K9 dimethylation(GO:0036123)
0.3	2.1	GO:0016255	attachment of GPI anchor to protein(GO:0016255)
0.3	2.4	GO:0043686	co-translational protein modification(GO:0043686)
0.3	8.3	GO:0034314	Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.3	2.8	GO:0045351	type I interferon biosynthetic process(GO:0045351)
0.3	1.7	GO:0014842	regulation of skeletal muscle satellite cell proliferation(GO:0014842)
0.3	0.7	GO:0036091	positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.3	2.0	GO:2000210	positive regulation of anoikis(GO:2000210)
0.3	1.0	GO:0031161	phosphatidylinositol catabolic process(GO:0031161)
0.3	9.2	GO:0035313	wound healing, spreading of epidermal cells(GO:0035313)
0.3	1.7	GO:0030311	poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.3	1.7	GO:1900744	regulation of p38MAPK cascade(GO:1900744)
0.3	1.3	GO:1900113	negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.3	2.0	GO:0006048	UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.3	2.0	GO:0032264	IMP salvage(GO:0032264)
0.3	3.0	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.3	2.0	GO:0032964	collagen biosynthetic process(GO:0032964)
0.3	2.6	GO:0015732	prostaglandin transport(GO:0015732)
0.3	1.3	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.3	4.5	GO:0000305	response to oxygen radical(GO:0000305)
0.3	9.3	GO:0015701	bicarbonate transport(GO:0015701)
0.3	3.2	GO:0016486	peptide hormone processing(GO:0016486)
0.3	0.6	GO:0019042	viral latency(GO:0019042) release from viral latency(GO:0019046)
0.3	1.0	GO:1900040	regulation of interleukin-2 secretion(GO:1900040)
0.3	8.3	GO:0045907	positive regulation of vasoconstriction(GO:0045907)
0.3	0.9	GO:0009249	protein lipoylation(GO:0009249)
0.3	3.1	GO:0090070	positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.3	0.3	GO:1902174	positive regulation of keratinocyte apoptotic process(GO:1902174)
0.3	3.3	GO:0002347	response to tumor cell(GO:0002347)
0.3	2.4	GO:0009651	response to salt stress(GO:0009651)
0.3	4.2	GO:0080182	histone H3-K4 trimethylation(GO:0080182)
0.3	2.4	GO:0006309	apoptotic DNA fragmentation(GO:0006309)
0.3	2.0	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.3	6.0	GO:0072348	sulfur compound transport(GO:0072348)
0.3	0.9	GO:1901740	negative regulation of myoblast fusion(GO:1901740)
0.3	3.5	GO:0070633	transepithelial transport(GO:0070633)
0.3	2.0	GO:0043922	negative regulation by host of viral transcription(GO:0043922)
0.3	2.8	GO:0051151	negative regulation of smooth muscle cell differentiation(GO:0051151)
0.3	1.1	GO:1904117	cellular response to vasopressin(GO:1904117)
0.3	4.5	GO:0048240	sperm capacitation(GO:0048240)
0.3	2.2	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
0.3	3.4	GO:0071157	negative regulation of cell cycle arrest(GO:0071157)
0.3	2.5	GO:0070235	regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.3	1.1	GO:0019262	N-acetylneuraminate catabolic process(GO:0019262)
0.3	1.4	GO:0031119	tRNA pseudouridine synthesis(GO:0031119)
0.3	0.8	GO:1990108	protein linear deubiquitination(GO:1990108)
0.3	2.2	GO:1904424	regulation of GTP binding(GO:1904424)
0.3	0.3	GO:0043132	NAD transport(GO:0043132)
0.3	3.6	GO:0070262	peptidyl-serine dephosphorylation(GO:0070262)
0.3	1.4	GO:0051569	regulation of histone H3-K4 methylation(GO:0051569)
0.3	5.2	GO:0043044	ATP-dependent chromatin remodeling(GO:0043044)
0.3	0.3	GO:0002069	columnar/cuboidal epithelial cell maturation(GO:0002069)
0.3	2.7	GO:0036342	post-anal tail morphogenesis(GO:0036342)
0.3	2.7	GO:0071380	cellular response to prostaglandin E stimulus(GO:0071380)
0.3	0.8	GO:0015781	pyrimidine nucleotide-sugar transport(GO:0015781)
0.3	1.8	GO:0048535	lymph node development(GO:0048535)
0.3	1.1	GO:0006419	alanyl-tRNA aminoacylation(GO:0006419)
0.3	1.6	GO:0000055	ribosomal large subunit export from nucleus(GO:0000055)
0.3	0.8	GO:0006438	valyl-tRNA aminoacylation(GO:0006438)
0.3	1.0	GO:0072711	cellular response to hydroxyurea(GO:0072711)
0.3	1.0	GO:0006972	hyperosmotic response(GO:0006972)
0.3	1.5	GO:0034724	DNA replication-independent nucleosome organization(GO:0034724)
0.3	2.8	GO:0048733	sebaceous gland development(GO:0048733)
0.3	1.5	GO:0034472	snRNA 3'-end processing(GO:0034472)
0.3	1.0	GO:0072675	osteoclast fusion(GO:0072675)
0.2	2.2	GO:0072502	cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.2	0.2	GO:2001185	regulation of CD8-positive, alpha-beta T cell activation(GO:2001185)
0.2	7.5	GO:0038061	NIK/NF-kappaB signaling(GO:0038061)
0.2	1.0	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.2	1.7	GO:0045003	DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.2	3.2	GO:0042744	hydrogen peroxide catabolic process(GO:0042744)
0.2	0.2	GO:0060157	urinary bladder development(GO:0060157)
0.2	1.2	GO:0009446	putrescine biosynthetic process(GO:0009446)
0.2	1.0	GO:0006271	DNA strand elongation involved in DNA replication(GO:0006271)
0.2	1.9	GO:0032790	ribosome disassembly(GO:0032790)
0.2	5.0	GO:0001954	positive regulation of cell-matrix adhesion(GO:0001954)
0.2	1.0	GO:0039531	regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway(GO:0039531)
0.2	6.5	GO:0006730	one-carbon metabolic process(GO:0006730)
0.2	1.4	GO:0044034	negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.2	4.0	GO:0051642	centrosome localization(GO:0051642)
0.2	6.2	GO:0031124	mRNA 3'-end processing(GO:0031124)
0.2	3.5	GO:0006098	pentose-phosphate shunt(GO:0006098) glyceraldehyde-3-phosphate metabolic process(GO:0019682)
0.2	1.8	GO:0016973	poly(A)+ mRNA export from nucleus(GO:0016973)
0.2	1.6	GO:0071377	cellular response to glucagon stimulus(GO:0071377)
0.2	0.5	GO:0030242	pexophagy(GO:0030242) CVT pathway(GO:0032258)
0.2	3.4	GO:0006379	mRNA cleavage(GO:0006379)
0.2	2.2	GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504)
0.2	0.9	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.2	7.6	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0006919)
0.2	3.3	GO:0015937	coenzyme A biosynthetic process(GO:0015937)
0.2	3.3	GO:0045070	positive regulation of viral genome replication(GO:0045070)
0.2	0.7	GO:0070638	nicotinamide riboside catabolic process(GO:0006738) nicotinamide riboside metabolic process(GO:0046495) pyridine nucleoside metabolic process(GO:0070637) pyridine nucleoside catabolic process(GO:0070638)
0.2	0.9	GO:0070172	positive regulation of tooth mineralization(GO:0070172)
0.2	3.2	GO:0045672	positive regulation of osteoclast differentiation(GO:0045672)
0.2	0.9	GO:1902608	regulation of large conductance calcium-activated potassium channel activity(GO:1902606) positive regulation of large conductance calcium-activated potassium channel activity(GO:1902608)
0.2	0.4	GO:1903912	positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493) negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912)
0.2	4.1	GO:0045604	regulation of epidermal cell differentiation(GO:0045604)
0.2	1.5	GO:0097264	self proteolysis(GO:0097264)
0.2	0.6	GO:0006059	hexitol metabolic process(GO:0006059)
0.2	1.1	GO:0042635	positive regulation of hair cycle(GO:0042635)
0.2	0.8	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.2	1.9	GO:0051013	microtubule severing(GO:0051013)
0.2	2.0	GO:0015760	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.2	1.6	GO:0060644	mammary gland epithelial cell differentiation(GO:0060644)
0.2	0.6	GO:0042350	GDP-L-fucose biosynthetic process(GO:0042350)
0.2	1.8	GO:0001731	formation of translation preinitiation complex(GO:0001731)
0.2	1.4	GO:0006659	phosphatidylserine biosynthetic process(GO:0006659)
0.2	0.6	GO:0098507	polynucleotide 5' dephosphorylation(GO:0098507)
0.2	0.6	GO:0016584	nucleosome positioning(GO:0016584)
0.2	2.4	GO:1904037	positive regulation of epithelial cell apoptotic process(GO:1904037)
0.2	3.5	GO:0050962	detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.2	0.4	GO:1903336	negative regulation of vacuolar transport(GO:1903336)
0.2	4.1	GO:0048009	insulin-like growth factor receptor signaling pathway(GO:0048009)
0.2	1.7	GO:0060575	intestinal epithelial cell differentiation(GO:0060575)
0.2	0.8	GO:1903575	cornified envelope assembly(GO:1903575)
0.2	7.4	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.2	0.9	GO:0030149	sphingolipid catabolic process(GO:0030149)
0.2	1.6	GO:0008340	determination of adult lifespan(GO:0008340)
0.2	3.4	GO:0003351	epithelial cilium movement(GO:0003351)
0.2	1.2	GO:0035329	hippo signaling(GO:0035329)
0.2	6.2	GO:0014066	regulation of phosphatidylinositol 3-kinase signaling(GO:0014066)
0.2	2.1	GO:1900037	regulation of cellular response to hypoxia(GO:1900037)
0.2	1.1	GO:1990440	positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.2	1.2	GO:0033120	positive regulation of RNA splicing(GO:0033120)
0.2	0.7	GO:0001555	oocyte growth(GO:0001555)
0.2	2.2	GO:0034587	piRNA metabolic process(GO:0034587)
0.2	0.5	GO:0045065	cytotoxic T cell differentiation(GO:0045065)
0.2	6.1	GO:0043966	histone H3 acetylation(GO:0043966)
0.2	16.9	GO:0006302	double-strand break repair(GO:0006302)
0.2	2.0	GO:0032042	mitochondrial DNA metabolic process(GO:0032042)
0.2	2.2	GO:0006646	phosphatidylethanolamine biosynthetic process(GO:0006646)
0.2	1.8	GO:0001773	myeloid dendritic cell activation(GO:0001773)
0.2	0.5	GO:0032472	Golgi calcium ion transport(GO:0032472)
0.2	1.3	GO:0006622	protein targeting to lysosome(GO:0006622)
0.2	0.5	GO:0009227	nucleotide-sugar catabolic process(GO:0009227)
0.2	0.5	GO:0048227	plasma membrane to endosome transport(GO:0048227)
0.2	0.5	GO:0015864	pyrimidine nucleoside transport(GO:0015864)
0.2	1.4	GO:0001702	gastrulation with mouth forming second(GO:0001702)
0.2	4.0	GO:0016925	protein sumoylation(GO:0016925)
0.2	1.3	GO:0061298	retina vasculature development in camera-type eye(GO:0061298)
0.2	2.1	GO:0032331	negative regulation of chondrocyte differentiation(GO:0032331)
0.2	3.9	GO:0006879	cellular iron ion homeostasis(GO:0006879)
0.1	1.2	GO:0006308	DNA catabolic process(GO:0006308)
0.1	1.2	GO:0003417	growth plate cartilage development(GO:0003417)
0.1	0.4	GO:0036066	protein O-linked fucosylation(GO:0036066)
0.1	8.7	GO:1902017	regulation of cilium assembly(GO:1902017)
0.1	3.4	GO:0030488	tRNA methylation(GO:0030488)
0.1	0.7	GO:2000060	positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060)
0.1	1.0	GO:0043031	negative regulation of macrophage activation(GO:0043031)
0.1	0.7	GO:0042772	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978) DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.1	0.8	GO:0007398	ectoderm development(GO:0007398)
0.1	1.0	GO:0030903	notochord development(GO:0030903)
0.1	0.1	GO:0071481	cellular response to X-ray(GO:0071481)
0.1	1.8	GO:0021692	cerebellar Purkinje cell layer morphogenesis(GO:0021692)
0.1	0.3	GO:0001180	transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.1	2.7	GO:0008333	endosome to lysosome transport(GO:0008333)
0.1	1.5	GO:0070166	enamel mineralization(GO:0070166)
0.1	2.0	GO:0060038	cardiac muscle cell proliferation(GO:0060038)
0.1	1.6	GO:0035066	positive regulation of histone acetylation(GO:0035066)
0.1	0.7	GO:0032511	late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.1	1.3	GO:0032211	negative regulation of telomere maintenance via telomerase(GO:0032211)
0.1	0.3	GO:0045064	negative regulation of CD4-positive, alpha-beta T cell differentiation(GO:0043371) T-helper 2 cell differentiation(GO:0045064) negative regulation of T-helper cell differentiation(GO:0045623) regulation of T-helper 2 cell differentiation(GO:0045628)
0.1	0.5	GO:0015879	carnitine transport(GO:0015879)
0.1	3.0	GO:1903557	positive regulation of tumor necrosis factor production(GO:0032760) positive regulation of tumor necrosis factor superfamily cytokine production(GO:1903557)
0.1	0.3	GO:0060969	negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing(GO:0060969)
0.1	0.5	GO:1900426	positive regulation of defense response to bacterium(GO:1900426)
0.1	2.9	GO:0030199	collagen fibril organization(GO:0030199)
0.1	1.6	GO:0006515	misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.1	2.8	GO:0009880	embryonic pattern specification(GO:0009880)
0.1	10.2	GO:0007051	spindle organization(GO:0007051)
0.1	2.7	GO:0006284	base-excision repair(GO:0006284)
0.1	1.0	GO:0031293	membrane protein intracellular domain proteolysis(GO:0031293)
0.1	1.4	GO:0030490	maturation of SSU-rRNA(GO:0030490)
0.1	0.2	GO:0070475	rRNA base methylation(GO:0070475)
0.1	2.7	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512)
0.1	0.8	GO:0035767	endothelial cell chemotaxis(GO:0035767)
0.1	1.6	GO:0051601	exocyst localization(GO:0051601)
0.1	3.4	GO:0000187	activation of MAPK activity(GO:0000187)
0.1	10.1	GO:0007286	spermatid development(GO:0007286)
0.1	2.8	GO:0060976	coronary vasculature development(GO:0060976)
0.1	0.9	GO:0006703	estrogen biosynthetic process(GO:0006703)
0.1	0.7	GO:0017196	N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1	0.6	GO:1902043	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.1	0.3	GO:0044375	regulation of peroxisome size(GO:0044375)
0.1	2.3	GO:0030728	ovulation(GO:0030728)
0.1	0.3	GO:0070831	basement membrane assembly(GO:0070831)
0.1	0.4	GO:1902031	regulation of NADP metabolic process(GO:1902031)
0.1	0.2	GO:0035063	nuclear speck organization(GO:0035063)
0.1	0.9	GO:0051533	positive regulation of NFAT protein import into nucleus(GO:0051533)
0.1	4.7	GO:0001523	retinoid metabolic process(GO:0001523)
0.1	0.9	GO:0009235	cobalamin metabolic process(GO:0009235)
0.1	18.6	GO:0010951	negative regulation of endopeptidase activity(GO:0010951)
0.1	0.6	GO:0001887	selenium compound metabolic process(GO:0001887)
0.1	1.2	GO:0048546	digestive tract morphogenesis(GO:0048546)
0.1	1.6	GO:0043277	apoptotic cell clearance(GO:0043277)
0.1	20.5	GO:0007283	spermatogenesis(GO:0007283) male gamete generation(GO:0048232)
0.1	0.6	GO:0002943	tRNA dihydrouridine synthesis(GO:0002943)
0.1	0.6	GO:0097428	protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.1	0.1	GO:0034486	vacuolar transmembrane transport(GO:0034486) chaperone-mediated protein transport involved in chaperone-mediated autophagy(GO:0061741)
0.1	3.9	GO:0042255	ribosome assembly(GO:0042255)
0.1	0.5	GO:0070986	left/right axis specification(GO:0070986)
0.1	1.8	GO:0007205	protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.1	2.8	GO:0007179	transforming growth factor beta receptor signaling pathway(GO:0007179)
0.1	0.9	GO:0010718	positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.1	2.1	GO:0030500	regulation of bone mineralization(GO:0030500)
0.1	1.4	GO:0045292	mRNA cis splicing, via spliceosome(GO:0045292)
0.1	6.1	GO:0042113	B cell activation(GO:0042113)
0.1	2.1	GO:0001843	neural tube closure(GO:0001843) primary neural tube formation(GO:0014020) tube closure(GO:0060606)
0.1	0.7	GO:0045954	positive regulation of natural killer cell mediated immunity(GO:0002717) positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.1	1.0	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.1	0.5	GO:0046638	positive regulation of alpha-beta T cell differentiation(GO:0046638)
0.1	1.6	GO:0022617	extracellular matrix disassembly(GO:0022617)
0.1	1.1	GO:0000387	spliceosomal snRNP assembly(GO:0000387)
0.1	0.2	GO:0006591	ornithine metabolic process(GO:0006591)
0.1	0.9	GO:0006376	mRNA splice site selection(GO:0006376)
0.1	0.3	GO:0032988	ribonucleoprotein complex disassembly(GO:0032988)
0.1	1.1	GO:0072698	protein localization to microtubule cytoskeleton(GO:0072698)
0.1	0.9	GO:0000245	spliceosomal complex assembly(GO:0000245)
0.1	0.8	GO:0000731	DNA synthesis involved in DNA repair(GO:0000731)
0.1	0.4	GO:0060179	male mating behavior(GO:0060179)
0.1	0.4	GO:0043984	histone H4-K16 acetylation(GO:0043984)
0.1	0.2	GO:1901098	positive regulation of autophagosome maturation(GO:1901098)
0.1	0.6	GO:0006368	transcription elongation from RNA polymerase II promoter(GO:0006368)
0.1	0.2	GO:0097435	fibril organization(GO:0097435)
0.0	0.7	GO:0006801	superoxide metabolic process(GO:0006801)
0.0	0.1	GO:0003413	chondrocyte differentiation involved in endochondral bone morphogenesis(GO:0003413)
0.0	1.6	GO:0051057	positive regulation of small GTPase mediated signal transduction(GO:0051057)
0.0	0.8	GO:0071526	semaphorin-plexin signaling pathway(GO:0071526)
0.0	0.1	GO:0003215	cardiac right ventricle morphogenesis(GO:0003215)
0.0	0.6	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.0	0.4	GO:0032329	serine transport(GO:0032329)
0.0	0.3	GO:0006561	proline biosynthetic process(GO:0006561)
0.0	0.6	GO:0003382	epithelial cell morphogenesis(GO:0003382)
0.0	0.0	GO:0006701	progesterone biosynthetic process(GO:0006701)
0.0	1.1	GO:0007368	determination of left/right symmetry(GO:0007368)
0.0	10.7	GO:0043547	positive regulation of GTPase activity(GO:0043547)
0.0	2.4	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.0	0.5	GO:0031047	gene silencing by RNA(GO:0031047)
0.0	0.1	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0	0.5	GO:0035458	cellular response to interferon-beta(GO:0035458)
0.0	0.3	GO:0001867	complement activation, lectin pathway(GO:0001867)
0.0	0.7	GO:0018345	protein palmitoylation(GO:0018345)
0.0	0.9	GO:0032543	mitochondrial translation(GO:0032543)
0.0	0.2	GO:0002053	positive regulation of mesenchymal cell proliferation(GO:0002053)
0.0	0.2	GO:0040019	positive regulation of embryonic development(GO:0040019)
0.0	0.8	GO:0030198	extracellular matrix organization(GO:0030198)
0.0	0.2	GO:0048268	clathrin coat assembly(GO:0048268)
0.0	0.1	GO:0032049	cardiolipin biosynthetic process(GO:0032049)
0.0	0.1	GO:0051568	histone H3-K4 methylation(GO:0051568)
0.0	0.1	GO:0006183	GTP biosynthetic process(GO:0006183)
0.0	0.0	GO:0006824	cobalt ion transport(GO:0006824)
0.0	0.0	GO:0002369	T cell cytokine production(GO:0002369)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
10.4	41.7	GO:0031436	BRCA1-BARD1 complex(GO:0031436)
6.1	6.1	GO:0035189	Rb-E2F complex(GO:0035189)
6.1	48.5	GO:0000796	condensin complex(GO:0000796)
5.8	23.4	GO:0097149	centralspindlin complex(GO:0097149)
5.7	17.2	GO:0008537	proteasome activator complex(GO:0008537)
5.2	46.7	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
4.5	36.4	GO:0097443	sorting endosome(GO:0097443)
4.5	13.5	GO:0097124	cyclin A2-CDK2 complex(GO:0097124)
4.3	34.3	GO:0044194	cytolytic granule(GO:0044194)
3.8	11.3	GO:0000811	GINS complex(GO:0000811)
3.6	18.1	GO:0071953	elastic fiber(GO:0071953)
3.2	9.6	GO:0097543	ciliary inversin compartment(GO:0097543)
3.2	12.7	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
2.9	8.7	GO:0044317	rod spherule(GO:0044317)
2.8	53.2	GO:0032433	filopodium tip(GO:0032433)
2.8	8.3	GO:0033186	CAF-1 complex(GO:0033186)
2.7	8.2	GO:0005944	phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
2.7	8.1	GO:1990423	RZZ complex(GO:1990423)
2.7	10.8	GO:0070876	SOSS complex(GO:0070876)
2.4	4.8	GO:1990005	granular vesicle(GO:1990005)
2.2	9.0	GO:0005971	ribonucleoside-diphosphate reductase complex(GO:0005971)
2.2	8.7	GO:0097427	microtubule bundle(GO:0097427)
2.1	10.3	GO:0043293	apoptosome(GO:0043293)
2.0	20.4	GO:0070652	HAUS complex(GO:0070652)
1.9	7.5	GO:0043564	Ku70:Ku80 complex(GO:0043564)
1.9	7.4	GO:0032021	NELF complex(GO:0032021)
1.8	27.5	GO:0043657	host(GO:0018995) host cell(GO:0043657)
1.8	7.2	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
1.8	5.3	GO:0034666	integrin alpha2-beta1 complex(GO:0034666)
1.8	30.1	GO:0033202	Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
1.7	8.6	GO:0044614	nuclear pore cytoplasmic filaments(GO:0044614)
1.7	8.6	GO:0045098	type III intermediate filament(GO:0045098)
1.7	5.2	GO:0035692	macrophage migration inhibitory factor receptor complex(GO:0035692)
1.7	11.9	GO:0016602	CCAAT-binding factor complex(GO:0016602)
1.7	11.8	GO:0071203	WASH complex(GO:0071203)
1.7	16.5	GO:0070776	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
1.6	11.5	GO:0001651	dense fibrillar component(GO:0001651)
1.6	3.3	GO:0034667	integrin alpha3-beta1 complex(GO:0034667)
1.6	8.1	GO:0070695	FHF complex(GO:0070695)
1.6	8.0	GO:1990726	Lsm1-7-Pat1 complex(GO:1990726)
1.6	7.9	GO:0098536	deuterosome(GO:0098536)
1.6	12.6	GO:0070578	RISC-loading complex(GO:0070578)
1.5	20.1	GO:0016514	SWI/SNF complex(GO:0016514)
1.5	4.6	GO:0030981	cortical microtubule cytoskeleton(GO:0030981)
1.5	4.5	GO:0061574	ASAP complex(GO:0061574)
1.5	16.4	GO:0005915	zonula adherens(GO:0005915)
1.4	31.6	GO:0090545	NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
1.4	14.2	GO:0032593	insulin-responsive compartment(GO:0032593)
1.3	38.0	GO:0030867	rough endoplasmic reticulum membrane(GO:0030867)
1.3	3.8	GO:0035101	FACT complex(GO:0035101)
1.3	16.6	GO:0005885	Arp2/3 protein complex(GO:0005885)
1.3	8.8	GO:0034993	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
1.3	3.8	GO:0032807	DNA ligase IV complex(GO:0032807)
1.2	10.9	GO:0000812	Swr1 complex(GO:0000812)
1.2	4.8	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
1.2	8.3	GO:0031264	death-inducing signaling complex(GO:0031264)
1.1	8.0	GO:0005828	kinetochore microtubule(GO:0005828)
1.1	14.8	GO:0002199	zona pellucida receptor complex(GO:0002199)
1.1	10.2	GO:0000138	Golgi trans cisterna(GO:0000138)
1.1	13.5	GO:0035631	CD40 receptor complex(GO:0035631)
1.1	10.0	GO:0000808	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
1.1	3.3	GO:0005745	m-AAA complex(GO:0005745)
1.1	2.2	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
1.1	3.3	GO:0055087	Ski complex(GO:0055087)
1.1	3.2	GO:0043511	inhibin complex(GO:0043511)
1.1	6.3	GO:1990111	spermatoproteasome complex(GO:1990111)
1.1	3.2	GO:0071149	TEAD-2-YAP complex(GO:0071149)
1.1	8.4	GO:0031211	serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
1.0	3.1	GO:0070557	PCNA-p21 complex(GO:0070557)
1.0	13.2	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
1.0	3.0	GO:0032798	Swi5-Sfr1 complex(GO:0032798)
1.0	2.0	GO:1990630	IRE1-RACK1-PP2A complex(GO:1990630)
1.0	73.1	GO:0005811	lipid particle(GO:0005811)
0.9	4.7	GO:0031262	Ndc80 complex(GO:0031262)
0.9	6.4	GO:0042382	paraspeckles(GO:0042382)
0.9	27.0	GO:0005719	nuclear euchromatin(GO:0005719)
0.9	11.6	GO:0044232	organelle membrane contact site(GO:0044232)
0.9	7.1	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
0.9	4.4	GO:0001739	sex chromatin(GO:0001739)
0.9	7.0	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.9	21.0	GO:0035145	exon-exon junction complex(GO:0035145)
0.9	7.0	GO:0044322	endoplasmic reticulum quality control compartment(GO:0044322)
0.9	8.7	GO:0042788	polysomal ribosome(GO:0042788)
0.9	11.3	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.8	3.4	GO:0000220	vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.8	10.0	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
0.8	5.0	GO:0034464	BBSome(GO:0034464)
0.8	4.1	GO:0097165	nuclear stress granule(GO:0097165)
0.8	31.9	GO:0097610	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.8	4.6	GO:0001740	Barr body(GO:0001740)
0.8	72.9	GO:0005913	cell-cell adherens junction(GO:0005913)
0.8	16.0	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.8	1.5	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.8	2.3	GO:0071942	XPC complex(GO:0071942)
0.8	3.8	GO:0034455	t-UTP complex(GO:0034455)
0.7	2.2	GO:1990923	PET complex(GO:1990923)
0.7	22.9	GO:0034451	centriolar satellite(GO:0034451)
0.7	5.1	GO:0060205	cytoplasmic membrane-bounded vesicle lumen(GO:0060205)
0.7	2.9	GO:0032133	chromosome passenger complex(GO:0032133)
0.7	34.9	GO:0008023	transcription elongation factor complex(GO:0008023)
0.7	3.5	GO:0042825	TAP complex(GO:0042825)
0.7	19.3	GO:0042588	zymogen granule(GO:0042588)
0.7	3.4	GO:0016035	zeta DNA polymerase complex(GO:0016035)
0.7	2.7	GO:0070522	ERCC4-ERCC1 complex(GO:0070522)
0.7	9.4	GO:0072687	meiotic spindle(GO:0072687)
0.7	5.4	GO:0097433	dense body(GO:0097433)
0.7	2.6	GO:0072379	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.7	3.9	GO:0030896	checkpoint clamp complex(GO:0030896)
0.6	3.9	GO:0033093	Weibel-Palade body(GO:0033093)
0.6	4.5	GO:0034991	nuclear meiotic cohesin complex(GO:0034991)
0.6	1.9	GO:0048269	methionine adenosyltransferase complex(GO:0048269)
0.6	7.0	GO:0070938	contractile ring(GO:0070938)
0.6	7.5	GO:0097431	mitotic spindle pole(GO:0097431)
0.6	8.8	GO:0030061	mitochondrial crista(GO:0030061)
0.6	1.9	GO:0036488	CHOP-C/EBP complex(GO:0036488)
0.6	6.8	GO:0016580	Sin3 complex(GO:0016580)
0.6	2.5	GO:0036156	inner dynein arm(GO:0036156)
0.6	4.9	GO:0042555	MCM complex(GO:0042555)
0.6	7.9	GO:0031143	pseudopodium(GO:0031143)
0.6	3.0	GO:0031080	nuclear pore outer ring(GO:0031080)
0.6	16.3	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.6	12.0	GO:0005682	U5 snRNP(GO:0005682)
0.6	1.8	GO:0097227	sperm annulus(GO:0097227)
0.6	15.4	GO:0000788	nuclear nucleosome(GO:0000788)
0.6	1.8	GO:0034457	Mpp10 complex(GO:0034457)
0.6	64.3	GO:0030496	midbody(GO:0030496)
0.6	5.8	GO:0045179	apical cortex(GO:0045179)
0.6	9.2	GO:0042612	MHC class I protein complex(GO:0042612)
0.6	4.0	GO:0042587	glycogen granule(GO:0042587)
0.6	4.0	GO:0030991	intraciliary transport particle A(GO:0030991)
0.6	4.5	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.6	21.9	GO:0000795	synaptonemal complex(GO:0000795)
0.6	1.7	GO:0071001	U4/U6 snRNP(GO:0071001)
0.5	1.6	GO:0072487	MSL complex(GO:0072487)
0.5	3.2	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.5	4.2	GO:0098645	collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.5	3.1	GO:0070847	core mediator complex(GO:0070847)
0.5	6.7	GO:0000780	condensed nuclear chromosome, centromeric region(GO:0000780)
0.5	3.1	GO:0071817	MMXD complex(GO:0071817)
0.5	39.8	GO:0032432	actin filament bundle(GO:0032432)
0.5	3.0	GO:0036157	outer dynein arm(GO:0036157)
0.5	5.0	GO:0035102	PRC1 complex(GO:0035102)
0.5	3.0	GO:0005879	axonemal microtubule(GO:0005879)
0.5	5.4	GO:0001673	male germ cell nucleus(GO:0001673)
0.5	2.4	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.5	1.9	GO:0000322	storage vacuole(GO:0000322)
0.5	6.2	GO:0030914	STAGA complex(GO:0030914)
0.5	2.4	GO:0005672	transcription factor TFIIA complex(GO:0005672)
0.5	3.8	GO:0051286	cell tip(GO:0051286)
0.5	4.6	GO:0042583	chromaffin granule(GO:0042583)
0.5	7.8	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.5	2.7	GO:0042641	actomyosin(GO:0042641)
0.5	1.8	GO:0043625	delta DNA polymerase complex(GO:0043625)
0.5	2.3	GO:0070195	growth hormone receptor complex(GO:0070195)
0.5	8.1	GO:0005849	mRNA cleavage factor complex(GO:0005849)
0.4	3.1	GO:0031314	extrinsic component of mitochondrial inner membrane(GO:0031314)
0.4	1.8	GO:0043259	laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259)
0.4	1.3	GO:1990879	CST complex(GO:1990879)
0.4	13.2	GO:0000777	condensed chromosome kinetochore(GO:0000777)
0.4	5.2	GO:0010369	chromocenter(GO:0010369)
0.4	1.7	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.4	49.3	GO:0001650	fibrillar center(GO:0001650)
0.4	96.3	GO:0000790	nuclear chromatin(GO:0000790)
0.4	3.9	GO:0000445	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.4	29.1	GO:0071013	catalytic step 2 spliceosome(GO:0071013)
0.4	14.0	GO:0016235	aggresome(GO:0016235)
0.4	3.0	GO:0002139	stereocilia coupling link(GO:0002139)
0.4	0.7	GO:0070761	pre-snoRNP complex(GO:0070761)
0.4	10.3	GO:0005771	multivesicular body(GO:0005771)
0.4	7.5	GO:0002080	acrosomal membrane(GO:0002080)
0.3	2.1	GO:0042765	GPI-anchor transamidase complex(GO:0042765)
0.3	3.8	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.3	1.4	GO:0032299	ribonuclease H2 complex(GO:0032299)
0.3	5.4	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.3	102.5	GO:0009897	external side of plasma membrane(GO:0009897)
0.3	2.3	GO:0005677	chromatin silencing complex(GO:0005677)
0.3	4.8	GO:0036038	MKS complex(GO:0036038)
0.3	0.9	GO:0031074	nucleocytoplasmic shuttling complex(GO:0031074)
0.3	45.8	GO:0001726	ruffle(GO:0001726)
0.3	94.4	GO:0005925	focal adhesion(GO:0005925)
0.3	9.7	GO:0030131	clathrin adaptor complex(GO:0030131)
0.3	1.9	GO:0001652	granular component(GO:0001652)
0.3	1.2	GO:0000974	Prp19 complex(GO:0000974)
0.3	3.7	GO:0051233	spindle midzone(GO:0051233)
0.3	0.9	GO:0034657	GID complex(GO:0034657)
0.3	25.3	GO:0005604	basement membrane(GO:0005604)
0.3	13.1	GO:0005871	kinesin complex(GO:0005871)
0.3	3.5	GO:0031462	Cul2-RING ubiquitin ligase complex(GO:0031462)
0.3	3.1	GO:0072546	ER membrane protein complex(GO:0072546)
0.3	8.7	GO:0032420	stereocilium(GO:0032420)
0.3	1.7	GO:0061700	GATOR2 complex(GO:0061700)
0.3	2.2	GO:0042613	MHC class II protein complex(GO:0042613)
0.3	1.4	GO:0097524	sperm plasma membrane(GO:0097524)
0.3	0.8	GO:0030478	actin cap(GO:0030478)
0.3	1.1	GO:0034399	nuclear periphery(GO:0034399)
0.3	1.1	GO:0005642	annulate lamellae(GO:0005642)
0.3	1.0	GO:0031417	NatC complex(GO:0031417)
0.3	1.0	GO:0030915	Smc5-Smc6 complex(GO:0030915)
0.3	1.5	GO:0032584	growth cone membrane(GO:0032584)
0.3	1.3	GO:0097539	ciliary transition fiber(GO:0097539)
0.2	1.2	GO:0005721	pericentric heterochromatin(GO:0005721)
0.2	1.0	GO:0097422	tubular endosome(GO:0097422)
0.2	6.4	GO:0005844	polysome(GO:0005844)
0.2	4.9	GO:0044665	MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.2	2.2	GO:0042405	nuclear inclusion body(GO:0042405)
0.2	3.6	GO:0097440	apical dendrite(GO:0097440)
0.2	1.4	GO:0034388	Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.2	4.3	GO:0031231	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.2	1.1	GO:0030015	CCR4-NOT core complex(GO:0030015)
0.2	1.3	GO:0045293	MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.2	19.0	GO:0072562	blood microparticle(GO:0072562)
0.2	8.1	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.2	5.4	GO:0030992	intraciliary transport particle B(GO:0030992)
0.2	3.6	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.2	0.6	GO:0031680	G-protein beta/gamma-subunit complex(GO:0031680)
0.2	3.8	GO:0005680	anaphase-promoting complex(GO:0005680)
0.2	2.7	GO:0032391	photoreceptor connecting cilium(GO:0032391)
0.2	1.4	GO:0035371	microtubule plus-end(GO:0035371)
0.2	8.9	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.2	12.3	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.2	4.8	GO:0005876	spindle microtubule(GO:0005876)
0.2	12.7	GO:0016363	nuclear matrix(GO:0016363)
0.2	0.6	GO:0031010	ISWI-type complex(GO:0031010)
0.2	11.8	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
0.2	8.5	GO:0005814	centriole(GO:0005814)
0.2	6.3	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.2	1.3	GO:0001741	XY body(GO:0001741)
0.2	7.4	GO:0030286	dynein complex(GO:0030286)
0.2	1.8	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.2	7.1	GO:0045178	basal part of cell(GO:0045178)
0.2	0.9	GO:0043527	tRNA methyltransferase complex(GO:0043527)
0.2	10.2	GO:0005930	axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.2	1.8	GO:0042622	photoreceptor outer segment membrane(GO:0042622)
0.2	1.2	GO:0031258	lamellipodium membrane(GO:0031258)
0.2	1.5	GO:0002177	manchette(GO:0002177)
0.2	0.5	GO:0001405	presequence translocase-associated import motor(GO:0001405)
0.2	1.0	GO:0098553	integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553) cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.2	3.2	GO:0043194	axon initial segment(GO:0043194)
0.2	2.3	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.2	1.5	GO:0034719	SMN-Sm protein complex(GO:0034719)
0.2	0.8	GO:0031467	Cul7-RING ubiquitin ligase complex(GO:0031467)
0.2	9.8	GO:0036064	ciliary basal body(GO:0036064)
0.1	5.1	GO:0005912	adherens junction(GO:0005912)
0.1	0.6	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.1	0.4	GO:0030689	Noc complex(GO:0030689)
0.1	1.0	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.1	6.9	GO:0005902	microvillus(GO:0005902)
0.1	8.3	GO:0005901	caveola(GO:0005901)
0.1	2.9	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1	5.8	GO:0048770	melanosome(GO:0042470) pigment granule(GO:0048770)
0.1	1.8	GO:0005639	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.1	4.2	GO:0016459	myosin complex(GO:0016459)
0.1	25.6	GO:0031965	nuclear membrane(GO:0031965)
0.1	5.0	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.1	0.7	GO:0005832	chaperonin-containing T-complex(GO:0005832)
0.1	2.7	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.1	5.4	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.1	3.1	GO:0000781	chromosome, telomeric region(GO:0000781)
0.1	1.7	GO:0030864	cortical actin cytoskeleton(GO:0030864)
0.1	0.8	GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1	1.0	GO:0045334	clathrin-coated endocytic vesicle(GO:0045334)
0.1	1.2	GO:0031932	TORC2 complex(GO:0031932)
0.1	1.0	GO:0070161	anchoring junction(GO:0070161)
0.1	1.1	GO:0030008	TRAPP complex(GO:0030008)
0.1	26.6	GO:0031012	extracellular matrix(GO:0031012)
0.1	0.6	GO:0005685	U1 snRNP(GO:0005685)
0.1	2.3	GO:0015030	Cajal body(GO:0015030)
0.1	4.5	GO:0016605	PML body(GO:0016605)
0.1	26.9	GO:0016604	nuclear body(GO:0016604)
0.1	0.6	GO:0019013	viral nucleocapsid(GO:0019013)
0.1	0.7	GO:0044666	MLL3/4 complex(GO:0044666)
0.1	34.6	GO:0005730	nucleolus(GO:0005730)
0.1	0.5	GO:0044305	calyx of Held(GO:0044305)
0.1	0.2	GO:0098835	presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835)
0.0	2.5	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.0	1.5	GO:0005801	cis-Golgi network(GO:0005801)
0.0	0.5	GO:0031083	BLOC-1 complex(GO:0031083)
0.0	1.2	GO:0005681	spliceosomal complex(GO:0005681)
0.0	0.4	GO:0035686	sperm fibrous sheath(GO:0035686)
0.0	0.1	GO:0030906	retromer, cargo-selective complex(GO:0030906)
0.0	0.3	GO:0030014	CCR4-NOT complex(GO:0030014)
0.0	0.5	GO:0005751	mitochondrial respiratory chain complex IV(GO:0005751)
0.0	0.1	GO:0043541	UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.0	0.1	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.0	0.1	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
0.0	0.6	GO:0042645	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
16.6	49.9	GO:0060002	plus-end directed microfilament motor activity(GO:0060002)
9.3	55.9	GO:0015173	aromatic amino acid transmembrane transporter activity(GO:0015173)
8.6	25.9	GO:0003945	N-acetyllactosamine synthase activity(GO:0003945)
7.0	21.1	GO:0031249	denatured protein binding(GO:0031249)
6.3	31.7	GO:0030348	syntaxin-3 binding(GO:0030348)
6.1	18.2	GO:0035851	Krueppel-associated box domain binding(GO:0035851)
6.0	6.0	GO:0015141	succinate transmembrane transporter activity(GO:0015141)
5.4	16.1	GO:0001069	regulatory region RNA binding(GO:0001069)
4.9	14.8	GO:0030977	taurine binding(GO:0030977)
4.4	17.7	GO:0071535	RING-like zinc finger domain binding(GO:0071535)
4.2	88.4	GO:0098641	cadherin binding involved in cell-cell adhesion(GO:0098641)
4.1	16.4	GO:0042134	rRNA primary transcript binding(GO:0042134)
4.1	12.3	GO:0016882	cyclo-ligase activity(GO:0016882)
4.1	16.3	GO:0004771	sterol esterase activity(GO:0004771)
4.0	15.9	GO:0070644	vitamin D response element binding(GO:0070644)
3.9	30.9	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021) vascular endothelial growth factor binding(GO:0038085)
3.6	10.8	GO:0051916	granulocyte colony-stimulating factor binding(GO:0051916)
3.5	10.6	GO:0004066	asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
3.5	24.2	GO:0003896	DNA primase activity(GO:0003896)
3.4	20.3	GO:0017040	ceramidase activity(GO:0017040)
3.3	13.4	GO:0004052	arachidonate 12-lipoxygenase activity(GO:0004052)
3.3	19.8	GO:0046979	TAP binding(GO:0046977) TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
3.3	13.0	GO:0044547	DNA topoisomerase binding(GO:0044547)
3.2	9.7	GO:0016403	dimethylargininase activity(GO:0016403)
3.1	9.4	GO:0097677	STAT family protein binding(GO:0097677)
3.1	9.3	GO:0008481	sphinganine kinase activity(GO:0008481)
3.1	12.4	GO:0017077	oxidative phosphorylation uncoupler activity(GO:0017077)
2.9	20.6	GO:0046976	histone methyltransferase activity (H3-K27 specific)(GO:0046976)
2.9	5.7	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
2.7	8.2	GO:0000991	transcription factor activity, core RNA polymerase II binding(GO:0000991)
2.7	10.7	GO:0015137	citrate transmembrane transporter activity(GO:0015137)
2.7	8.0	GO:0047522	15-oxoprostaglandin 13-oxidase activity(GO:0047522)
2.5	7.5	GO:0048030	disaccharide binding(GO:0048030)
2.4	7.1	GO:0019797	procollagen-proline 3-dioxygenase activity(GO:0019797)
2.3	9.3	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
2.3	7.0	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
2.3	27.7	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
2.3	16.0	GO:0061133	endopeptidase activator activity(GO:0061133)
2.2	11.2	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
2.2	8.9	GO:0001225	RNA polymerase II transcription coactivator binding(GO:0001225)
2.2	6.6	GO:0004655	porphobilinogen synthase activity(GO:0004655)
2.2	8.7	GO:0086089	voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
2.1	29.2	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
2.1	14.5	GO:0004065	arylsulfatase activity(GO:0004065)
2.1	6.2	GO:0001716	L-amino-acid oxidase activity(GO:0001716)
2.1	2.1	GO:0035373	chondroitin sulfate proteoglycan binding(GO:0035373)
2.0	26.1	GO:0015924	mannosyl-oligosaccharide mannosidase activity(GO:0015924)
2.0	11.9	GO:0035662	Toll-like receptor 4 binding(GO:0035662)
1.9	5.8	GO:0015203	polyamine transmembrane transporter activity(GO:0015203) putrescine transmembrane transporter activity(GO:0015489)
1.9	5.6	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
1.9	5.6	GO:0052656	branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
1.9	11.1	GO:0034988	Fc-gamma receptor I complex binding(GO:0034988)
1.8	1.8	GO:0031493	nucleosomal histone binding(GO:0031493)
1.8	11.0	GO:0008420	CTD phosphatase activity(GO:0008420)
1.8	10.8	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
1.8	17.8	GO:0005114	type II transforming growth factor beta receptor binding(GO:0005114)
1.8	8.8	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
1.7	15.5	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
1.7	56.7	GO:0031492	nucleosomal DNA binding(GO:0031492)
1.7	8.4	GO:0016454	serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
1.7	6.7	GO:0048408	epidermal growth factor binding(GO:0048408)
1.7	5.0	GO:0004315	3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315) phosphopantetheine binding(GO:0031177)
1.7	5.0	GO:0005168	neurotrophin TRKA receptor binding(GO:0005168)
1.6	37.3	GO:0004602	glutathione peroxidase activity(GO:0004602)
1.6	4.8	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
1.6	7.9	GO:0015616	DNA translocase activity(GO:0015616)
1.6	7.8	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
1.6	7.8	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
1.6	3.1	GO:0055105	ubiquitin-protein transferase inhibitor activity(GO:0055105)
1.5	4.5	GO:0004335	galactokinase activity(GO:0004335)
1.5	9.0	GO:0004748	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
1.4	8.7	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
1.4	5.7	GO:0047179	platelet-activating factor acetyltransferase activity(GO:0047179)
1.4	10.0	GO:0008934	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832)
1.4	14.9	GO:0004331	6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
1.4	2.7	GO:1990599	3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
1.3	10.7	GO:0003680	AT DNA binding(GO:0003680)
1.3	6.7	GO:0097493	structural molecule activity conferring elasticity(GO:0097493)
1.3	5.3	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
1.3	5.3	GO:0004967	glucagon receptor activity(GO:0004967)
1.3	13.1	GO:0051959	dynein light intermediate chain binding(GO:0051959)
1.3	18.4	GO:0042301	phosphate ion binding(GO:0042301)
1.3	5.2	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
1.3	5.2	GO:0050610	oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
1.3	11.5	GO:0042285	xylosyltransferase activity(GO:0042285)
1.3	6.4	GO:0004920	interleukin-10 receptor activity(GO:0004920)
1.3	6.4	GO:0010997	anaphase-promoting complex binding(GO:0010997)
1.3	34.2	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
1.3	7.5	GO:0051575	5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
1.2	19.9	GO:0004806	triglyceride lipase activity(GO:0004806)
1.2	5.0	GO:0044378	non-sequence-specific DNA binding, bending(GO:0044378)
1.2	20.4	GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
1.2	5.9	GO:0004140	dephospho-CoA kinase activity(GO:0004140)
1.2	14.0	GO:1990405	protein antigen binding(GO:1990405)
1.1	3.4	GO:0047025	3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
1.1	11.3	GO:0035613	RNA stem-loop binding(GO:0035613)
1.1	3.4	GO:0016971	flavin-linked sulfhydryl oxidase activity(GO:0016971)
1.1	4.5	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
1.1	2.2	GO:0035877	death effector domain binding(GO:0035877)
1.1	12.2	GO:0017154	semaphorin receptor activity(GO:0017154)
1.1	3.3	GO:1902379	chemoattractant activity involved in axon guidance(GO:1902379)
1.1	4.4	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
1.1	3.3	GO:0050145	nucleoside phosphate kinase activity(GO:0050145)
1.1	3.3	GO:0005135	erythropoietin receptor binding(GO:0005128) interleukin-3 receptor binding(GO:0005135)
1.1	2.2	GO:0005163	nerve growth factor receptor binding(GO:0005163)
1.1	52.4	GO:0070063	RNA polymerase binding(GO:0070063)
1.1	5.3	GO:0098639	collagen binding involved in cell-matrix adhesion(GO:0098639)
1.1	9.5	GO:0001094	TFIID-class transcription factor binding(GO:0001094)
1.1	3.2	GO:0034057	RNA strand-exchange activity(GO:0034057)
1.0	11.5	GO:0043138	3'-5' DNA helicase activity(GO:0043138)
1.0	6.2	GO:0005324	long-chain fatty acid transporter activity(GO:0005324)
1.0	6.2	GO:0070180	large ribosomal subunit rRNA binding(GO:0070180)
1.0	3.1	GO:0004478	methionine adenosyltransferase activity(GO:0004478)
1.0	6.1	GO:0033142	progesterone receptor binding(GO:0033142)
1.0	1.0	GO:0052833	inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
1.0	4.0	GO:0016416	carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
1.0	7.0	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
1.0	1.0	GO:0016532	superoxide dismutase copper chaperone activity(GO:0016532)
1.0	3.8	GO:0047623	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.9	2.8	GO:0034041	lipid-transporting ATPase activity(GO:0034040) sterol-transporting ATPase activity(GO:0034041) glycoprotein transporter activity(GO:0034437)
0.9	2.7	GO:0004528	phosphodiesterase I activity(GO:0004528)
0.9	4.5	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.9	19.9	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.9	2.7	GO:0004483	mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.9	3.6	GO:0047184	1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.9	2.7	GO:0034485	phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.9	2.7	GO:1990460	leptin receptor binding(GO:1990460)
0.9	1.8	GO:1990269	RNA polymerase II C-terminal domain phosphoserine binding(GO:1990269)
0.9	5.3	GO:0016018	cyclosporin A binding(GO:0016018)
0.9	3.5	GO:0033192	calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.9	4.3	GO:0043515	kinetochore binding(GO:0043515)
0.9	3.4	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.9	2.6	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.9	2.6	GO:0070573	metallodipeptidase activity(GO:0070573)
0.8	4.2	GO:0004169	dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.8	4.2	GO:0032027	myosin light chain binding(GO:0032027)
0.8	1.7	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.8	10.8	GO:0005041	low-density lipoprotein receptor activity(GO:0005041)
0.8	3.3	GO:1990247	N6-methyladenosine-containing RNA binding(GO:1990247)
0.8	3.3	GO:0000822	inositol hexakisphosphate binding(GO:0000822)
0.8	3.3	GO:0005143	interleukin-12 receptor binding(GO:0005143)
0.8	20.3	GO:0001784	phosphotyrosine binding(GO:0001784)
0.8	17.9	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.8	2.4	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.8	3.2	GO:0045159	myosin II binding(GO:0045159)
0.8	4.8	GO:0034452	dynactin binding(GO:0034452)
0.8	4.7	GO:0034647	histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.8	10.0	GO:0003688	DNA replication origin binding(GO:0003688)
0.8	2.3	GO:0010385	double-stranded methylated DNA binding(GO:0010385)
0.8	2.3	GO:0000309	nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.8	4.6	GO:0048039	ubiquinone binding(GO:0048039)
0.8	3.8	GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.8	3.0	GO:0019784	NEDD8-specific protease activity(GO:0019784)
0.8	22.6	GO:0001103	RNA polymerase II repressing transcription factor binding(GO:0001103)
0.8	3.8	GO:0016427	tRNA (cytosine) methyltransferase activity(GO:0016427)
0.7	16.3	GO:0051010	microtubule plus-end binding(GO:0051010)
0.7	0.7	GO:0017050	D-erythro-sphingosine kinase activity(GO:0017050)
0.7	3.7	GO:1990254	keratin filament binding(GO:1990254)
0.7	6.6	GO:0000340	RNA 7-methylguanosine cap binding(GO:0000340)
0.7	3.6	GO:0000702	oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.7	3.6	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.7	2.9	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.7	2.8	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
0.7	16.3	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.7	7.0	GO:0051400	BH domain binding(GO:0051400)
0.7	4.2	GO:0004568	chitinase activity(GO:0004568)
0.7	2.1	GO:0015184	L-cystine transmembrane transporter activity(GO:0015184)
0.7	6.3	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
0.7	7.6	GO:0070513	death domain binding(GO:0070513)
0.7	4.8	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.7	1.4	GO:0002060	purine nucleobase binding(GO:0002060)
0.7	11.6	GO:0070717	poly-purine tract binding(GO:0070717)
0.7	3.4	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.7	2.7	GO:0017089	glycolipid transporter activity(GO:0017089)
0.7	8.1	GO:0045294	alpha-catenin binding(GO:0045294)
0.7	8.1	GO:0022889	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.7	40.3	GO:0035064	methylated histone binding(GO:0035064)
0.7	6.0	GO:0055056	D-glucose transmembrane transporter activity(GO:0055056)
0.7	2.7	GO:0015111	iodide transmembrane transporter activity(GO:0015111)
0.7	7.9	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.7	2.0	GO:0051734	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.7	2.6	GO:0016833	oxo-acid-lyase activity(GO:0016833)
0.6	25.9	GO:0051019	mitogen-activated protein kinase binding(GO:0051019)
0.6	1.9	GO:0016230	sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.6	3.2	GO:0005134	interleukin-2 receptor binding(GO:0005134)
0.6	2.5	GO:0070915	lysophosphatidic acid receptor activity(GO:0070915)
0.6	3.8	GO:0030976	thiamine pyrophosphate binding(GO:0030976)
0.6	2.5	GO:0004609	phosphatidylserine decarboxylase activity(GO:0004609)
0.6	1.8	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.6	4.1	GO:0048495	Roundabout binding(GO:0048495)
0.6	2.3	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.6	15.7	GO:0005452	inorganic anion exchanger activity(GO:0005452)
0.6	1.7	GO:0004830	tryptophan-tRNA ligase activity(GO:0004830)
0.6	25.1	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.6	2.3	GO:0004903	growth hormone receptor activity(GO:0004903)
0.6	15.3	GO:0035173	histone kinase activity(GO:0035173)
0.6	4.5	GO:0043495	protein anchor(GO:0043495)
0.6	7.2	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.6	2.2	GO:0098518	polynucleotide phosphatase activity(GO:0098518)
0.5	1.6	GO:0032217	riboflavin transporter activity(GO:0032217)
0.5	2.7	GO:0001010	transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.5	1.6	GO:0042610	CD8 receptor binding(GO:0042610)
0.5	30.7	GO:0042805	actinin binding(GO:0042805)
0.5	3.2	GO:0017070	U6 snRNA binding(GO:0017070)
0.5	3.7	GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.5	2.7	GO:0000700	mismatch base pair DNA N-glycosylase activity(GO:0000700) MutLalpha complex binding(GO:0032405)
0.5	2.7	GO:0004103	choline kinase activity(GO:0004103)
0.5	11.1	GO:0070840	dynein complex binding(GO:0070840)
0.5	3.7	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.5	2.1	GO:0032190	acrosin binding(GO:0032190)
0.5	2.1	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.5	17.3	GO:0042162	telomeric DNA binding(GO:0042162)
0.5	11.6	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.5	11.6	GO:0005112	Notch binding(GO:0005112)
0.5	5.5	GO:0070411	I-SMAD binding(GO:0070411)
0.5	10.3	GO:0031490	chromatin DNA binding(GO:0031490)
0.5	11.7	GO:0071889	14-3-3 protein binding(GO:0071889)
0.5	3.4	GO:0000990	transcription factor activity, core RNA polymerase binding(GO:0000990)
0.5	2.4	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.5	1.4	GO:0035539	8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
0.5	75.7	GO:0001047	core promoter binding(GO:0001047)
0.5	1.9	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.5	11.4	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.5	3.3	GO:0098599	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.5	7.0	GO:0017160	Ral GTPase binding(GO:0017160)
0.5	11.7	GO:0042974	retinoic acid receptor binding(GO:0042974)
0.5	17.1	GO:0018024	histone-lysine N-methyltransferase activity(GO:0018024)
0.5	10.1	GO:0003951	NAD+ kinase activity(GO:0003951)
0.5	37.2	GO:0008026	ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.5	2.7	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.5	3.6	GO:0005166	neurotrophin p75 receptor binding(GO:0005166)
0.5	1.8	GO:0046624	sphingolipid transporter activity(GO:0046624)
0.5	2.7	GO:0034711	inhibin binding(GO:0034711)
0.4	1.8	GO:0008310	single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.4	1.8	GO:1990189	peptide-serine-N-acetyltransferase activity(GO:1990189)
0.4	8.0	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.4	2.7	GO:0008865	glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.4	36.1	GO:0004896	cytokine receptor activity(GO:0004896)
0.4	1.3	GO:0004839	ubiquitin activating enzyme activity(GO:0004839)
0.4	3.1	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.4	2.6	GO:0035325	Toll-like receptor binding(GO:0035325)
0.4	5.6	GO:0042171	lysophosphatidic acid acyltransferase activity(GO:0042171)
0.4	6.1	GO:0008409	5'-3' exonuclease activity(GO:0008409)
0.4	2.6	GO:0015245	fatty acid transporter activity(GO:0015245)
0.4	0.9	GO:0010484	H3 histone acetyltransferase activity(GO:0010484)
0.4	5.1	GO:0004000	adenosine deaminase activity(GO:0004000)
0.4	75.3	GO:0061135	endopeptidase inhibitor activity(GO:0004866) endopeptidase regulator activity(GO:0061135)
0.4	1.3	GO:0035651	1-phosphatidylinositol 4-kinase activity(GO:0004430) AP-3 adaptor complex binding(GO:0035651)
0.4	3.4	GO:0008432	JUN kinase binding(GO:0008432)
0.4	1.7	GO:0008532	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.4	9.7	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.4	7.6	GO:0031491	nucleosome binding(GO:0031491)
0.4	8.4	GO:0003887	DNA-directed DNA polymerase activity(GO:0003887)
0.4	5.5	GO:0005225	volume-sensitive anion channel activity(GO:0005225)
0.4	2.1	GO:0034235	GPI anchor binding(GO:0034235)
0.4	15.0	GO:0001105	RNA polymerase II transcription coactivator activity(GO:0001105)
0.4	1.2	GO:0005146	leukemia inhibitory factor receptor binding(GO:0005146)
0.4	2.1	GO:1990239	steroid hormone binding(GO:1990239)
0.4	3.7	GO:0001223	transcription coactivator binding(GO:0001223)
0.4	0.8	GO:0004370	glycerol kinase activity(GO:0004370)
0.4	1.6	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.4	1.2	GO:0046592	polyamine oxidase activity(GO:0046592)
0.4	6.5	GO:0001618	virus receptor activity(GO:0001618)
0.4	3.6	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
0.4	30.6	GO:0003697	single-stranded DNA binding(GO:0003697)
0.4	2.7	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.4	7.2	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.4	3.0	GO:0097027	ubiquitin-protein transferase activator activity(GO:0097027)
0.4	11.0	GO:0003785	actin monomer binding(GO:0003785)
0.4	6.7	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.4	2.6	GO:0070569	uridylyltransferase activity(GO:0070569)
0.4	65.3	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.4	2.6	GO:0003707	steroid hormone receptor activity(GO:0003707)
0.4	1.1	GO:0009384	N-acylmannosamine kinase activity(GO:0009384)
0.4	1.1	GO:0052724	inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.4	3.3	GO:0071933	Arp2/3 complex binding(GO:0071933)
0.4	7.3	GO:0005521	lamin binding(GO:0005521)
0.4	5.7	GO:0031418	L-ascorbic acid binding(GO:0031418)
0.4	2.1	GO:0003960	NADPH:quinone reductase activity(GO:0003960)
0.4	11.3	GO:0008408	3'-5' exonuclease activity(GO:0008408)
0.4	6.4	GO:0001106	RNA polymerase II transcription corepressor activity(GO:0001106)
0.4	2.5	GO:0008484	sulfuric ester hydrolase activity(GO:0008484)
0.4	1.1	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
0.3	10.8	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.3	14.6	GO:0045182	translation regulator activity(GO:0045182)
0.3	7.2	GO:0031996	thioesterase binding(GO:0031996)
0.3	3.0	GO:0003909	DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.3	1.0	GO:0031386	protein tag(GO:0031386)
0.3	0.7	GO:0004731	purine-nucleoside phosphorylase activity(GO:0004731)
0.3	1.6	GO:0004974	leukotriene receptor activity(GO:0004974)
0.3	1.3	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.3	3.8	GO:0031434	mitogen-activated protein kinase kinase binding(GO:0031434)
0.3	2.9	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.3	7.6	GO:0043014	alpha-tubulin binding(GO:0043014)
0.3	6.8	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.3	0.9	GO:0004774	succinate-CoA ligase activity(GO:0004774) succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.3	15.1	GO:0016879	ligase activity, forming carbon-nitrogen bonds(GO:0016879)
0.3	1.8	GO:0043208	glycosphingolipid binding(GO:0043208)
0.3	2.0	GO:0015315	hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.3	1.5	GO:0009019	tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.3	6.4	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.3	5.8	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.3	11.7	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.3	2.8	GO:0004526	ribonuclease P activity(GO:0004526)
0.3	2.2	GO:0034595	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439) inositol-polyphosphate 5-phosphatase activity(GO:0004445) phosphatidylinositol phosphate 5-phosphatase activity(GO:0034595)
0.3	2.5	GO:0015093	ferrous iron transmembrane transporter activity(GO:0015093)
0.3	1.4	GO:0004008	copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682)
0.3	33.2	GO:0003774	motor activity(GO:0003774)
0.3	3.3	GO:0017166	vinculin binding(GO:0017166)
0.3	3.0	GO:0070742	C2H2 zinc finger domain binding(GO:0070742)
0.3	3.8	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.3	4.5	GO:0005522	profilin binding(GO:0005522)
0.3	1.1	GO:0042289	MHC class II protein binding(GO:0042289)
0.3	3.7	GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.3	1.1	GO:0004813	alanine-tRNA ligase activity(GO:0004813)
0.3	0.8	GO:0004832	valine-tRNA ligase activity(GO:0004832)
0.3	7.3	GO:0050699	WW domain binding(GO:0050699)
0.3	3.6	GO:0050431	transforming growth factor beta binding(GO:0050431)
0.3	2.0	GO:0030291	protein serine/threonine kinase inhibitor activity(GO:0030291)
0.3	2.8	GO:0019789	SUMO transferase activity(GO:0019789)
0.3	4.3	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)
0.2	1.0	GO:0004165	dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.2	0.7	GO:0005375	copper ion transmembrane transporter activity(GO:0005375)
0.2	1.7	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.2	1.0	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.2	1.0	GO:0008970	phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.2	51.4	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.2	0.9	GO:0050733	RS domain binding(GO:0050733)
0.2	2.4	GO:0016889	endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.2	5.2	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.2	63.0	GO:0030695	GTPase regulator activity(GO:0030695)
0.2	1.6	GO:0005113	patched binding(GO:0005113)
0.2	1.1	GO:0016505	cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656) peptidase activator activity involved in apoptotic process(GO:0016505)
0.2	7.8	GO:0003690	double-stranded DNA binding(GO:0003690)
0.2	5.6	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.2	1.6	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.2	2.0	GO:0042609	CD4 receptor binding(GO:0042609)
0.2	0.7	GO:0042284	sphingolipid delta-4 desaturase activity(GO:0042284)
0.2	1.3	GO:0005536	glucose binding(GO:0005536)
0.2	6.1	GO:0030971	receptor tyrosine kinase binding(GO:0030971)
0.2	0.8	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.2	0.8	GO:0070883	pre-miRNA binding(GO:0070883)
0.2	3.4	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
0.2	3.0	GO:0050811	GABA receptor binding(GO:0050811)
0.2	1.7	GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.2	0.6	GO:0047057	oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.2	1.9	GO:0009922	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.2	3.5	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
0.2	0.5	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.2	0.9	GO:0016423	tRNA (guanine) methyltransferase activity(GO:0016423)
0.2	1.6	GO:0004622	lysophospholipase activity(GO:0004622)
0.2	1.1	GO:0043024	ribosomal small subunit binding(GO:0043024)
0.2	2.0	GO:0098632	protein binding involved in cell-cell adhesion(GO:0098632)
0.2	1.1	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.2	1.6	GO:0005161	platelet-derived growth factor receptor binding(GO:0005161)
0.2	2.4	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.2	2.9	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.2	0.5	GO:0015199	amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.2	16.7	GO:0008565	protein transporter activity(GO:0008565)
0.2	0.5	GO:0004159	uracil binding(GO:0002058) pyrimidine nucleobase binding(GO:0002061) dihydrouracil dehydrogenase (NAD+) activity(GO:0004159) dihydropyrimidine dehydrogenase (NADP+) activity(GO:0017113)
0.2	0.3	GO:1990782	protein tyrosine kinase binding(GO:1990782)
0.2	2.3	GO:0008179	adenylate cyclase binding(GO:0008179)
0.2	1.3	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.2	0.5	GO:0015389	pyrimidine- and adenine-specific:sodium symporter activity(GO:0015389)
0.2	2.7	GO:0017091	AU-rich element binding(GO:0017091)
0.2	2.0	GO:0042056	chemoattractant activity(GO:0042056)
0.2	29.3	GO:0043565	sequence-specific DNA binding(GO:0043565)
0.2	2.3	GO:0022848	acetylcholine-gated cation channel activity(GO:0022848)
0.2	0.6	GO:0050682	AF-2 domain binding(GO:0050682)
0.1	9.9	GO:0019208	phosphatase regulator activity(GO:0019208)
0.1	6.6	GO:0002039	p53 binding(GO:0002039)
0.1	2.0	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.1	0.4	GO:0008948	oxaloacetate decarboxylase activity(GO:0008948)
0.1	12.5	GO:0042393	histone binding(GO:0042393)
0.1	1.4	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.1	1.1	GO:0050321	tau-protein kinase activity(GO:0050321)
0.1	1.4	GO:0033170	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1	0.3	GO:0061629	RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1	1.1	GO:0030275	LRR domain binding(GO:0030275)
0.1	2.3	GO:0001191	transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191)
0.1	6.9	GO:0003725	double-stranded RNA binding(GO:0003725)
0.1	1.9	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
0.1	0.8	GO:0050897	cobalt ion binding(GO:0050897)
0.1	2.7	GO:0042288	MHC class I protein binding(GO:0042288)
0.1	2.8	GO:0004693	cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.1	3.5	GO:0003899	DNA-directed RNA polymerase activity(GO:0003899)
0.1	0.6	GO:0070401	NADP+ binding(GO:0070401)
0.1	0.9	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1	6.1	GO:0003743	translation initiation factor activity(GO:0003743)
0.1	48.7	GO:0000975	regulatory region DNA binding(GO:0000975) regulatory region nucleic acid binding(GO:0001067)
0.1	3.9	GO:0016667	oxidoreductase activity, acting on a sulfur group of donors(GO:0016667)
0.1	2.2	GO:0004601	peroxidase activity(GO:0004601) oxidoreductase activity, acting on peroxide as acceptor(GO:0016684)
0.1	7.3	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
0.1	2.4	GO:0043236	laminin binding(GO:0043236)
0.1	0.9	GO:0030911	TPR domain binding(GO:0030911)
0.1	0.6	GO:0017150	tRNA dihydrouridine synthase activity(GO:0017150)
0.1	0.9	GO:0004966	galanin receptor activity(GO:0004966)
0.1	3.4	GO:0043022	ribosome binding(GO:0043022)
0.1	13.9	GO:0005085	guanyl-nucleotide exchange factor activity(GO:0005085)
0.1	1.1	GO:0032183	SUMO binding(GO:0032183)
0.1	0.2	GO:0003831	beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.1	0.4	GO:0000829	inositol heptakisphosphate kinase activity(GO:0000829)
0.1	1.0	GO:0043274	phospholipase binding(GO:0043274)
0.1	0.2	GO:0042608	T cell receptor binding(GO:0042608)
0.1	0.7	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
0.1	0.3	GO:0008502	melatonin receptor activity(GO:0008502)
0.1	8.4	GO:0019902	phosphatase binding(GO:0019902)
0.1	6.8	GO:0017124	SH3 domain binding(GO:0017124)
0.1	0.4	GO:0008428	ribonuclease inhibitor activity(GO:0008428)
0.1	0.5	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.1	19.5	GO:0045296	cadherin binding(GO:0045296)
0.1	1.2	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1	1.3	GO:0010181	FMN binding(GO:0010181)
0.1	2.6	GO:0019707	protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1	0.2	GO:0008169	C-methyltransferase activity(GO:0008169)
0.1	0.5	GO:0015929	hexosaminidase activity(GO:0015929)
0.1	10.4	GO:0003700	nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.1	0.4	GO:0004322	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1	7.4	GO:0003682	chromatin binding(GO:0003682)
0.1	1.8	GO:0019955	cytokine binding(GO:0019955)
0.1	0.2	GO:0002151	G-quadruplex RNA binding(GO:0002151)
0.1	0.8	GO:0003684	damaged DNA binding(GO:0003684)
0.1	0.9	GO:0051879	Hsp90 protein binding(GO:0051879)
0.1	0.2	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.1	0.4	GO:0051787	misfolded protein binding(GO:0051787)
0.1	0.3	GO:0030280	structural constituent of epidermis(GO:0030280)
0.1	18.2	GO:0003677	DNA binding(GO:0003677)
0.0	0.1	GO:0097108	hedgehog family protein binding(GO:0097108)
0.0	0.6	GO:0004527	exonuclease activity(GO:0004527)
0.0	1.4	GO:0005109	frizzled binding(GO:0005109)
0.0	0.2	GO:0005052	peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0	0.4	GO:0008417	fucosyltransferase activity(GO:0008417)
0.0	0.1	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0	1.2	GO:0016831	carboxy-lyase activity(GO:0016831)
0.0	0.4	GO:0004551	nucleotide diphosphatase activity(GO:0004551)
0.0	0.6	GO:0051537	2 iron, 2 sulfur cluster binding(GO:0051537)
0.0	0.1	GO:0004126	cytidine deaminase activity(GO:0004126)
0.0	0.0	GO:0016886	ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0	4.9	GO:0003735	structural constituent of ribosome(GO:0003735)
0.0	0.1	GO:0004605	phosphatidate cytidylyltransferase activity(GO:0004605)
0.0	0.5	GO:0001076	transcription factor activity, RNA polymerase II transcription factor binding(GO:0001076)
0.0	0.3	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0	1.5	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.0	0.0	GO:0031752	D5 dopamine receptor binding(GO:0031752)
0.0	1.3	GO:0050839	cell adhesion molecule binding(GO:0050839)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.1	34.3	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
2.0	77.3	PID BARD1 PATHWAY	BARD1 signaling events
1.9	9.6	SIG IL4RECEPTOR IN B LYPHOCYTES	Genes related to IL4 rceptor signaling in B lymphocytes
1.9	9.5	ST JAK STAT PATHWAY	Jak-STAT Pathway
1.5	12.4	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
1.5	12.1	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
1.5	14.6	PID GMCSF PATHWAY	GMCSF-mediated signaling events
1.3	37.6	PID IL3 PATHWAY	IL3-mediated signaling events
1.3	47.9	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
1.3	59.6	PID AURORA B PATHWAY	Aurora B signaling
1.3	66.9	PID ILK PATHWAY	Integrin-linked kinase signaling
1.2	48.1	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
1.2	23.5	PID VEGFR1 PATHWAY	VEGFR1 specific signals
1.2	35.8	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
1.1	33.7	PID EPO PATHWAY	EPO signaling pathway
1.1	7.8	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
1.1	20.9	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
1.0	10.3	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
1.0	16.4	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
1.0	33.7	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
1.0	11.7	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
1.0	9.6	PID AVB3 OPN PATHWAY	Osteopontin-mediated events
0.9	3.8	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.9	2.8	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.9	3.6	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.9	27.0	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.9	40.9	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.8	12.5	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.8	7.2	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.8	5.3	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
0.7	39.3	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.7	7.3	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.7	32.6	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.7	22.4	PID ERBB4 PATHWAY	ErbB4 signaling events
0.7	23.6	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.7	19.9	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.7	25.9	PID PLK1 PATHWAY	PLK1 signaling events
0.7	13.6	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.7	12.2	PID IL27 PATHWAY	IL27-mediated signaling events
0.7	28.9	PID P53 REGULATION PATHWAY	p53 pathway
0.7	11.7	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.6	13.0	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.6	21.4	ST FAS SIGNALING PATHWAY	Fas Signaling Pathway
0.6	26.6	PID IL12 2PATHWAY	IL12-mediated signaling events
0.6	36.7	PID PDGFRB PATHWAY	PDGFR-beta signaling pathway
0.6	4.8	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.6	58.4	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
0.6	20.1	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.5	17.0	PID REG GR PATHWAY	Glucocorticoid receptor regulatory network
0.5	29.8	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
0.5	2.7	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.5	9.2	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.5	20.2	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.5	2.0	PID IGF1 PATHWAY	IGF1 pathway
0.5	27.3	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.5	14.7	PID IL4 2PATHWAY	IL4-mediated signaling events
0.5	5.6	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.4	6.7	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.4	10.5	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.4	2.1	PID HIV NEF PATHWAY	HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.4	6.9	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.4	2.4	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.4	6.2	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.4	5.4	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.3	10.3	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events
0.3	1.9	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.3	3.9	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.3	13.0	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.3	6.1	PID FANCONI PATHWAY	Fanconi anemia pathway
0.3	7.3	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.3	6.5	PID ATR PATHWAY	ATR signaling pathway
0.3	3.7	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.3	2.6	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.3	2.8	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.2	3.5	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.2	2.1	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.2	6.3	PID TELOMERASE PATHWAY	Regulation of Telomerase
0.2	8.0	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.2	2.0	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.2	3.5	PID RB 1PATHWAY	Regulation of retinoblastoma protein
0.2	2.1	PID BCR 5PATHWAY	BCR signaling pathway
0.2	1.5	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.2	5.0	PID RAS PATHWAY	Regulation of Ras family activation
0.2	5.8	PID CONE PATHWAY	Visual signal transduction: Cones
0.2	2.5	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.2	1.3	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.2	2.7	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.2	2.9	PID ERBB1 DOWNSTREAM PATHWAY	ErbB1 downstream signaling
0.2	1.4	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.2	3.1	PID RHOA PATHWAY	RhoA signaling pathway
0.2	8.4	WNT SIGNALING	Genes related to Wnt-mediated signal transduction
0.2	1.2	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.2	1.7	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.1	28.1	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1	1.3	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.1	1.2	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.1	3.2	PID LKB1 PATHWAY	LKB1 signaling events
0.1	13.5	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1	2.3	PID E2F PATHWAY	E2F transcription factor network
0.1	2.9	PID NOTCH PATHWAY	Notch signaling pathway
0.1	14.7	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.1	0.7	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.1	1.0	PID S1P META PATHWAY	Sphingosine 1-phosphate (S1P) pathway
0.0	0.7	PID AP1 PATHWAY	AP-1 transcription factor network
0.0	0.3	PID ATM PATHWAY	ATM pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.7	3.7	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
2.8	33.2	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
2.5	54.2	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
2.2	40.1	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
2.2	26.0	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
2.1	21.0	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
2.0	79.5	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
2.0	37.4	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
1.8	19.5	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
1.8	5.3	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
1.7	20.1	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
1.6	1.6	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
1.6	43.5	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
1.6	31.9	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
1.5	46.2	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
1.5	16.8	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
1.5	22.8	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
1.4	14.0	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
1.2	19.2	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
1.1	3.4	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
1.1	6.6	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
1.0	3.0	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
1.0	2.9	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
1.0	10.6	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.9	34.2	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.9	11.6	REACTOME IL 3 5 AND GM CSF SIGNALING	Genes involved in Interleukin-3, 5 and GM-CSF signaling
0.9	20.5	REACTOME FATTY ACYL COA BIOSYNTHESIS	Genes involved in Fatty Acyl-CoA Biosynthesis
0.9	15.1	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.9	14.2	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.8	95.2	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.8	38.5	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.8	9.0	REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.8	10.1	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.8	3.9	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.8	6.1	REACTOME INFLUENZA LIFE CYCLE	Genes involved in Influenza Life Cycle
0.8	5.3	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.7	12.7	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.7	7.3	REACTOME INTEGRATION OF PROVIRUS	Genes involved in Integration of provirus
0.7	21.7	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.7	7.8	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.6	2.6	REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.6	28.9	REACTOME PI3K EVENTS IN ERBB4 SIGNALING	Genes involved in PI3K events in ERBB4 signaling
0.6	17.3	REACTOME RNA POL I TRANSCRIPTION INITIATION	Genes involved in RNA Polymerase I Transcription Initiation
0.6	10.9	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.6	18.6	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.6	17.9	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.6	8.2	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.6	3.8	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.6	12.6	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.6	4.4	REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	Genes involved in CD28 dependent PI3K/Akt signaling
0.6	7.9	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.6	7.2	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.6	34.9	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.6	14.0	REACTOME BASE EXCISION REPAIR	Genes involved in Base Excision Repair
0.6	37.0	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.6	9.0	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.6	5.5	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.5	22.5	REACTOME MRNA 3 END PROCESSING	Genes involved in mRNA 3'-end processing
0.5	22.1	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.5	25.1	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.5	6.0	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.5	5.4	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.5	10.8	REACTOME FORMATION OF RNA POL II ELONGATION COMPLEX	Genes involved in Formation of RNA Pol II elongation complex
0.5	28.7	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.5	10.9	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.4	2.2	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.4	10.1	REACTOME DEADENYLATION DEPENDENT MRNA DECAY	Genes involved in Deadenylation-dependent mRNA decay
0.4	48.0	REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX	Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.4	1.7	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.4	8.6	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.4	23.5	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.4	5.2	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.4	8.7	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
0.4	2.0	REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	Genes involved in Sema3A PAK dependent Axon repulsion
0.4	2.3	REACTOME ACTIVATED POINT MUTANTS OF FGFR2	Genes involved in Activated point mutants of FGFR2
0.4	8.4	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.4	6.7	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.4	10.9	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.4	3.4	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.4	9.9	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.4	2.9	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.4	5.1	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.4	8.0	REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM	Genes involved in Transport of Mature Transcript to Cytoplasm
0.4	3.2	REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE	Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.3	7.2	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.3	2.7	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.3	2.0	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.3	0.7	REACTOME RNA POL I TRANSCRIPTION	Genes involved in RNA Polymerase I Transcription
0.3	3.7	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.3	2.8	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.3	9.4	REACTOME NUCLEAR SIGNALING BY ERBB4	Genes involved in Nuclear signaling by ERBB4
0.3	4.4	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.3	3.7	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.3	1.6	REACTOME EICOSANOID LIGAND BINDING RECEPTORS	Genes involved in Eicosanoid ligand-binding receptors
0.3	18.2	REACTOME DNA REPAIR	Genes involved in DNA Repair
0.3	4.5	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.3	2.6	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.3	1.5	REACTOME DOWNSTREAM SIGNAL TRANSDUCTION	Genes involved in Downstream signal transduction
0.2	1.7	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.2	4.5	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.2	21.9	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.2	1.1	REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA	Genes involved in Activation of Chaperones by ATF6-alpha
0.2	8.5	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.2	5.2	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.2	4.9	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.2	2.2	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.2	3.4	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.2	2.7	REACTOME FGFR4 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR4 ligand binding and activation
0.2	2.1	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.2	0.4	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.2	1.8	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.2	1.4	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.2	0.8	REACTOME MICRORNA MIRNA BIOGENESIS	Genes involved in MicroRNA (miRNA) Biogenesis
0.2	3.9	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.2	1.4	REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS	Genes involved in Activation of ATR in response to replication stress
0.1	1.5	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1	2.5	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.1	3.6	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1	6.4	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.1	0.5	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.1	0.5	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.1	2.0	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
0.1	4.6	REACTOME TRANS GOLGI NETWORK VESICLE BUDDING	Genes involved in trans-Golgi Network Vesicle Budding
0.1	1.2	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.1	6.0	REACTOME ER PHAGOSOME PATHWAY	Genes involved in ER-Phagosome pathway
0.1	4.9	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.1	0.3	REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1	Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.1	1.3	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.1	1.1	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.1	1.7	REACTOME KERATAN SULFATE KERATIN METABOLISM	Genes involved in Keratan sulfate/keratin metabolism
0.1	5.8	REACTOME GLYCOSAMINOGLYCAN METABOLISM	Genes involved in Glycosaminoglycan metabolism
0.1	0.5	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.1	6.8	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.1	1.2	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.0	0.8	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	0.6	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.0	0.7	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	2.0	REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS	Genes involved in Glycerophospholipid biosynthesis
0.0	0.6	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.2	REACTOME HOST INTERACTIONS OF HIV FACTORS	Genes involved in Host Interactions of HIV factors
0.0	0.3	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.5	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors

Results for Klf12_Klf14_Sp4

Z-value: 1.36

Motif logo

Transcription factors associated with Klf12_Klf14_Sp4

Activity-expression correlation:

Activity profile of Klf12_Klf14_Sp4 motif

Sorted Z-values of Klf12_Klf14_Sp4 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of Klf12_Klf14_Sp4

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: