ISMARA results: Id4

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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Id4

Z-value: 2.23

Motif logo

Transcription factors associated with Id4

Gene Symbol	Gene ID	Gene Info
Id4 NCBI RGD Ensembl	ENSRNOG00000016099	inhibitor of DNA binding 4, HLH protein

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Id4	rn6_v1_chr17_-_16695126_16695126	0.34	4.2e-10	Click!

Activity profile of Id4 motif

Sorted Z-values of Id4 motif

Top targets:

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr7_+_94130852 Show fit	120.00	ENSRNOT00000011485	Mal2 NCBI RGD Ensembl Show fit	mal, T-cell differentiation protein 2
chr1_-_54748763 Show fit	103.80	ENSRNOT00000074549	LOC100911027 NCBI RGD Ensembl Show fit	protein MAL2-like
chr1_-_102106127 Show fit	87.96	ENSRNOT00000028685	Kcnj11 NCBI RGD Ensembl Show fit	potassium voltage-gated channel subfamily J member 11
chr15_+_37806836 Show fit	68.16	ENSRNOT00000076285	Il17d NCBI RGD Ensembl Show fit	interleukin 17D
chr1_-_80331626 Show fit	65.88	ENSRNOT00000022577	AABR07002677.1 NCBI RGD Ensembl Show fit
chr9_-_80166807 Show fit	62.79	ENSRNOT00000079493	Igfbp5 NCBI RGD Ensembl Show fit	insulin-like growth factor binding protein 5
chr14_-_80169431 Show fit	61.51	ENSRNOT00000079769 ENSRNOT00000058315	Ablim2 NCBI RGD Ensembl Show fit	actin binding LIM protein family, member 2
chr5_+_151692108 Show fit	60.58	ENSRNOT00000086144	Fam46b NCBI RGD Ensembl Show fit	family with sequence similarity 46, member B
chr10_+_47281786 Show fit	59.70	ENSRNOT00000089123	Kcnj12 NCBI RGD Ensembl Show fit	potassium voltage-gated channel subfamily J member 12
chr8_-_130429132 Show fit	57.09	ENSRNOT00000026261	Hhatl NCBI RGD Ensembl Show fit	hedgehog acyltransferase-like
chr9_-_9985630 Show fit	56.33	ENSRNOT00000071780	Crb3 NCBI RGD Ensembl Show fit	crumbs 3, cell polarity complex component
chr12_+_30450316 Show fit	55.26	ENSRNOT00000001222	Phkg1 NCBI RGD Ensembl Show fit	phosphorylase kinase, gamma 1
chr8_-_116361343 Show fit	55.04	ENSRNOT00000066296	Sema3b NCBI RGD Ensembl Show fit	semaphorin 3B
chr10_+_77537340 Show fit	54.70	ENSRNOT00000003297	Tmem100 NCBI RGD Ensembl Show fit	transmembrane protein 100
chr10_+_40247436 Show fit	53.74	ENSRNOT00000079830	Gpx3 NCBI RGD Ensembl Show fit	glutathione peroxidase 3
chr1_+_199449973 Show fit	52.57	ENSRNOT00000029994	Trim72 NCBI RGD Ensembl Show fit	tripartite motif containing 72
chr11_-_88972176 Show fit	52.34	ENSRNOT00000002498	Pkp2 NCBI RGD Ensembl Show fit	plakophilin 2
chr1_-_254735548 Show fit	50.80	ENSRNOT00000025258	Ankrd1 NCBI RGD Ensembl Show fit	ankyrin repeat domain 1
chr10_-_103919605 Show fit	50.52	ENSRNOT00000004718	Hid1 NCBI RGD Ensembl Show fit	HID1 domain containing
chr16_-_49574314 Show fit	49.83	ENSRNOT00000017568 ENSRNOT00000085535 ENSRNOT00000017054	Pdlim3 NCBI RGD Ensembl Show fit	PDZ and LIM domain 3
chr16_-_81912738 Show fit	49.80	ENSRNOT00000087095	Mcf2l NCBI RGD Ensembl Show fit	MCF.2 cell line derived transforming sequence-like
chr11_+_27208564 Show fit	49.17	ENSRNOT00000002158	Map3k7cl NCBI RGD Ensembl Show fit	MAP3K7 C-terminal like
chr2_-_186245163 Show fit	48.20	ENSRNOT00000089339	Dclk2 NCBI RGD Ensembl Show fit	doublecortin-like kinase 2
chr8_+_57886168 Show fit	47.90	ENSRNOT00000039336	Exph5 NCBI RGD Ensembl Show fit	exophilin 5
chr2_+_242882306 Show fit	47.78	ENSRNOT00000013661	Ddit4l NCBI RGD Ensembl Show fit	DNA-damage-inducible transcript 4-like
chr1_-_100669684 Show fit	47.67	ENSRNOT00000091760	Myh14 NCBI RGD Ensembl Show fit	myosin heavy chain 14
chr9_-_88356716 Show fit	47.59	ENSRNOT00000077503	Col4a4 NCBI RGD Ensembl Show fit	collagen type IV alpha 4 chain
chr15_+_34251606 Show fit	47.58	ENSRNOT00000025725	Fitm1 NCBI RGD Ensembl Show fit	fat storage-inducing transmembrane protein 1
chr8_-_72836159 Show fit	46.81	ENSRNOT00000024617	Tpm1 NCBI RGD Ensembl Show fit	tropomyosin 1, alpha
chr2_-_24923128 Show fit	46.70	ENSRNOT00000044087	Pde8b NCBI RGD Ensembl Show fit	phosphodiesterase 8B
chr8_+_32018560 Show fit	46.43	ENSRNOT00000007358	Adamts8 NCBI RGD Ensembl Show fit	ADAM metallopeptidase with thrombospondin type 1 motif, 8
chr14_-_105055421 Show fit	45.39	ENSRNOT00000008274	Lgalsl NCBI RGD Ensembl Show fit	galectin-like
chr9_-_88357182 Show fit	44.73	ENSRNOT00000041176	Col4a4 NCBI RGD Ensembl Show fit	collagen type IV alpha 4 chain
chr18_+_56193978 Show fit	44.65	ENSRNOT00000041533 ENSRNOT00000080177	Camk2a NCBI RGD Ensembl Show fit	calcium/calmodulin-dependent protein kinase II alpha
chr7_-_130120579 Show fit	44.49	ENSRNOT00000044376	Mapk12 NCBI RGD Ensembl Show fit	mitogen-activated protein kinase 12
chr3_-_46726946 Show fit	44.37	ENSRNOT00000011030 ENSRNOT00000086576	Itgb6 NCBI RGD Ensembl Show fit	integrin subunit beta 6
chr12_+_28381982 Show fit	44.21	ENSRNOT00000076101	Wbscr17 NCBI RGD Ensembl Show fit	Williams-Beuren syndrome chromosome region 17
chr1_-_226353611 Show fit	43.84	ENSRNOT00000037624	Dagla NCBI RGD Ensembl Show fit	diacylglycerol lipase, alpha
chr2_+_3400977 Show fit	42.83	ENSRNOT00000093593	Mctp1 NCBI RGD Ensembl Show fit	multiple C2 and transmembrane domain containing 1
chr11_-_59110562 Show fit	42.83	ENSRNOT00000047907 ENSRNOT00000042024	Lsamp NCBI RGD Ensembl Show fit	limbic system-associated membrane protein
chr17_-_80320681 Show fit	42.07	ENSRNOT00000023637	C1ql3 NCBI RGD Ensembl Show fit	complement C1q like 3
chr3_+_2625015 Show fit	41.52	ENSRNOT00000018927	Npdc1 NCBI RGD Ensembl Show fit	neural proliferation, differentiation and control, 1
chr2_-_231521052 Show fit	41.11	ENSRNOT00000089534 ENSRNOT00000080470 ENSRNOT00000084756	Ank2 NCBI RGD Ensembl Show fit	ankyrin 2
chr7_-_50278842 Show fit	40.97	ENSRNOT00000088950	Syt1 NCBI RGD Ensembl Show fit	synaptotagmin 1
chr16_-_18757918 Show fit	40.75	ENSRNOT00000084172	Sftpd NCBI RGD Ensembl Show fit	surfactant protein D
chr5_+_128501847 Show fit	40.56	ENSRNOT00000010645	Rab3b NCBI RGD Ensembl Show fit	RAB3B, member RAS oncogene family
chr16_+_81616604 Show fit	40.24	ENSRNOT00000026392 ENSRNOT00000057740	Adprhl1 NCBI RGD Ensembl Show fit Grtp1 NCBI RGD Ensembl Show fit	ADP-ribosylhydrolase like 1 growth hormone regulated TBC protein 1
chr10_+_58342393 Show fit	39.30	ENSRNOT00000010358	Wscd1 NCBI RGD Ensembl Show fit	WSC domain containing 1
chr5_-_156141537 Show fit	38.85	ENSRNOT00000019004	Alpl NCBI RGD Ensembl Show fit	alkaline phosphatase, liver/bone/kidney
chr14_-_112946204 Show fit	38.69	ENSRNOT00000056813	LOC103690141 NCBI RGD Ensembl Show fit	coiled-coil domain-containing protein 85A-like
chr1_-_170397191 Show fit	38.27	ENSRNOT00000090181	Apbb1 NCBI RGD Ensembl Show fit	amyloid beta precursor protein binding family B member 1
chr1_-_72464492 Show fit	38.13	ENSRNOT00000068550	Nat14 NCBI RGD Ensembl Show fit	N-acetyltransferase 14
chr3_-_9037942 Show fit	37.61	ENSRNOT00000036770	Ier5l NCBI RGD Ensembl Show fit	immediate early response 5-like
chr9_+_99998275 Show fit	37.49	ENSRNOT00000074395	Gpc1 NCBI RGD Ensembl Show fit	glypican 1
chr7_-_120744602 Show fit	36.91	ENSRNOT00000018564	Kcnj4 NCBI RGD Ensembl Show fit	potassium voltage-gated channel subfamily J member 4
chr3_-_51054378 Show fit	36.87	ENSRNOT00000089243	Grb14 NCBI RGD Ensembl Show fit	growth factor receptor bound protein 14
chr5_+_164808323 Show fit	36.63	ENSRNOT00000011005	Nppa NCBI RGD Ensembl Show fit	natriuretic peptide A
chr17_-_27112820 Show fit	36.25	ENSRNOT00000018359	Bmp6 NCBI RGD Ensembl Show fit	bone morphogenetic protein 6
chr9_+_68414339 Show fit	36.13	ENSRNOT00000040778	Pard3b NCBI RGD Ensembl Show fit	par-3 family cell polarity regulator beta
chr3_-_161246351 Show fit	35.92	ENSRNOT00000020348	Tnnc2 NCBI RGD Ensembl Show fit	troponin C2, fast skeletal type
chr15_-_108210826 Show fit	35.55	ENSRNOT00000064705	Dock9 NCBI RGD Ensembl Show fit	dedicator of cytokinesis 9
chr5_+_1417478 Show fit	35.23	ENSRNOT00000008153 ENSRNOT00000085564	Jph1 NCBI RGD Ensembl Show fit	junctophilin 1
chr4_+_144382945 Show fit	35.23	ENSRNOT00000007601	Cav3 NCBI RGD Ensembl Show fit	caveolin 3
chr4_-_14490446 Show fit	35.09	ENSRNOT00000009132	Sema3c NCBI RGD Ensembl Show fit	semaphorin 3C
chr1_+_220335254 Show fit	34.92	ENSRNOT00000072261	Rin1 NCBI RGD Ensembl Show fit	Ras and Rab interactor 1
chr19_-_10101451 Show fit	34.23	ENSRNOT00000017629	Mmp15 NCBI RGD Ensembl Show fit	matrix metallopeptidase 15
chr1_-_215846911 Show fit	34.21	ENSRNOT00000089171	Igf2 NCBI RGD Ensembl Show fit	insulin-like growth factor 2
chr12_+_943006 Show fit	34.03	ENSRNOT00000001449	Kl NCBI RGD Ensembl Show fit	Klotho
chr7_+_123043503 Show fit	33.91	ENSRNOT00000026258 ENSRNOT00000086355	Tef NCBI RGD Ensembl Show fit	TEF, PAR bZIP transcription factor
chr14_+_36047144 Show fit	33.78	ENSRNOT00000003088	Lnx1 NCBI RGD Ensembl Show fit	ligand of numb-protein X 1
chr2_-_172361779 Show fit	33.70	ENSRNOT00000085876	Schip1 NCBI RGD Ensembl Show fit	schwannomin interacting protein 1
chr8_+_39997875 Show fit	33.55	ENSRNOT00000050609	Esam NCBI RGD Ensembl Show fit	endothelial cell adhesion molecule
chr8_+_119030875 Show fit	33.11	ENSRNOT00000028458	Myl3 NCBI RGD Ensembl Show fit	myosin light chain 3
chr11_+_87058616 Show fit	33.07	ENSRNOT00000002576 ENSRNOT00000082855	Prodh1 NCBI RGD Ensembl Show fit	proline dehydrogenase 1
chr20_-_4823475 Show fit	33.02	ENSRNOT00000082536 ENSRNOT00000001114	Atp6v1g2 NCBI RGD Ensembl Show fit	ATPase H+ transporting V1 subunit G2
chr7_-_140356209 Show fit	32.90	ENSRNOT00000077856	Rnd1 NCBI RGD Ensembl Show fit	Rho family GTPase 1
chr1_+_220428481 Show fit	32.78	ENSRNOT00000027335	LOC108348044 NCBI RGD Ensembl Show fit	ras and Rab interactor 1
chr10_-_82887497 Show fit	32.78	ENSRNOT00000005644	Itga3 NCBI RGD Ensembl Show fit	integrin subunit alpha 3
chr1_-_213650247 Show fit	32.75	ENSRNOT00000019679	Cox8b NCBI RGD Ensembl Show fit	cytochrome c oxidase, subunit VIIIb
chr18_+_16650806 Show fit	32.61	ENSRNOT00000093679 ENSRNOT00000041961 ENSRNOT00000093140	Fhod3 NCBI RGD Ensembl Show fit	formin homology 2 domain containing 3
chr2_+_251634431 Show fit	32.58	ENSRNOT00000045016	Ddah1 NCBI RGD Ensembl Show fit	dimethylarginine dimethylaminohydrolase 1
chr7_+_58814805 Show fit	32.56	ENSRNOT00000005909	Tspan8 NCBI RGD Ensembl Show fit	tetraspanin 8
chr9_-_104350308 Show fit	32.43	ENSRNOT00000033958	Slco4c1 NCBI RGD Ensembl Show fit	solute carrier organic anion transporter family, member 4C1
chrX_-_68562873 Show fit	32.37	ENSRNOT00000076193	Ophn1 NCBI RGD Ensembl Show fit	oligophrenin 1
chrX_-_68563137 Show fit	32.23	ENSRNOT00000034772	Ophn1 NCBI RGD Ensembl Show fit	oligophrenin 1
chr13_-_42263024 Show fit	32.03	ENSRNOT00000004741	Lypd1 NCBI RGD Ensembl Show fit	Ly6/Plaur domain containing 1
chr1_+_201055644 Show fit	31.86	ENSRNOT00000054937 ENSRNOT00000047161	Tacc2 NCBI RGD Ensembl Show fit	transforming, acidic coiled-coil containing protein 2
chr9_-_85626094 Show fit	31.73	ENSRNOT00000020919	Serpine2 NCBI RGD Ensembl Show fit	serpin family E member 2
chr10_+_86303727 Show fit	31.69	ENSRNOT00000037752	Ppp1r1b NCBI RGD Ensembl Show fit	protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr9_+_88357556 Show fit	30.73	ENSRNOT00000020669	Col4a3 NCBI RGD Ensembl Show fit	collagen type IV alpha 3 chain
chrX_+_157150655 Show fit	30.26	ENSRNOT00000090795	Pnck NCBI RGD Ensembl Show fit	pregnancy up-regulated nonubiquitous CaM kinase
chr10_-_20818128 Show fit	30.16	ENSRNOT00000011061	Wwc1 NCBI RGD Ensembl Show fit	WW and C2 domain containing 1
chr1_+_177093387 Show fit	30.06	ENSRNOT00000021858	Mical2 NCBI RGD Ensembl Show fit	microtubule associated monooxygenase, calponin and LIM domain containing 2
chr3_-_175709465 Show fit	29.54	ENSRNOT00000089971	Gata5 NCBI RGD Ensembl Show fit	GATA binding protein 5
chr9_+_111028575 Show fit	29.27	ENSRNOT00000043451	Pam NCBI RGD Ensembl Show fit	peptidylglycine alpha-amidating monooxygenase
chr1_+_101682172 Show fit	29.18	ENSRNOT00000028540	Car11 NCBI RGD Ensembl Show fit	carbonic anhydrase 11
chr4_+_120133713 Show fit	29.15	ENSRNOT00000017240	Gata2 NCBI RGD Ensembl Show fit	GATA binding protein 2
chr7_+_11383116 Show fit	29.08	ENSRNOT00000066348	Nmrk2 NCBI RGD Ensembl Show fit	nicotinamide riboside kinase 2
chr9_+_111028824 Show fit	28.76	ENSRNOT00000041418 ENSRNOT00000056457	Pam NCBI RGD Ensembl Show fit	peptidylglycine alpha-amidating monooxygenase
chr12_-_5773036 Show fit	28.63	ENSRNOT00000041365	Fry NCBI RGD Ensembl Show fit	FRY microtubule binding protein
chr1_-_84150084 Show fit	28.62	ENSRNOT00000028322	Ltbp4 NCBI RGD Ensembl Show fit	latent transforming growth factor beta binding protein 4
chr8_+_130416355 Show fit	28.50	ENSRNOT00000026234	Klhl40 NCBI RGD Ensembl Show fit	kelch-like family member 40
chr14_-_43072843 Show fit	28.08	ENSRNOT00000064263	Limch1 NCBI RGD Ensembl Show fit	LIM and calponin homology domains 1
chr19_-_645937 Show fit	28.07	ENSRNOT00000016521	Car7 NCBI RGD Ensembl Show fit	carbonic anhydrase 7
chr6_+_137184820 Show fit	28.07	ENSRNOT00000073796	Adssl1 NCBI RGD Ensembl Show fit	adenylosuccinate synthase like 1
chr14_-_112946875 Show fit	27.99	ENSRNOT00000081981	LOC103690141 NCBI RGD Ensembl Show fit	coiled-coil domain-containing protein 85A-like
chr3_+_58632476 Show fit	27.94	ENSRNOT00000010630	Rapgef4 NCBI RGD Ensembl Show fit	Rap guanine nucleotide exchange factor 4
chr1_+_215609036 Show fit	27.89	ENSRNOT00000076187	Tnni2 NCBI RGD Ensembl Show fit	troponin I2, fast skeletal type
chr1_-_146556171 Show fit	27.88	ENSRNOT00000017636	Arnt2 NCBI RGD Ensembl Show fit	aryl hydrocarbon receptor nuclear translocator 2
chr15_-_13228607 Show fit	27.81	ENSRNOT00000042010 ENSRNOT00000088214	Ptprg NCBI RGD Ensembl Show fit	protein tyrosine phosphatase, receptor type, G
chr13_+_52662996 Show fit	27.48	ENSRNOT00000047682	Tnnt2 NCBI RGD Ensembl Show fit	troponin T2, cardiac type
chr1_+_7252349 Show fit	27.40	ENSRNOT00000030329	Plagl1 NCBI RGD Ensembl Show fit	PLAG1 like zinc finger 1
chr9_+_82596355 Show fit	27.36	ENSRNOT00000065076	Speg NCBI RGD Ensembl Show fit	SPEG complex locus
chr9_+_82556573 Show fit	27.32	ENSRNOT00000026860	Des NCBI RGD Ensembl Show fit	desmin
chr5_+_158090173 Show fit	27.27	ENSRNOT00000088766 ENSRNOT00000079516 ENSRNOT00000092026	Tas1r2 NCBI RGD Ensembl Show fit	taste 1 receptor member 2
chr1_-_265573117 Show fit	27.11	ENSRNOT00000044195 ENSRNOT00000055915	LOC100911951 NCBI RGD Ensembl Show fit	Kv channel-interacting protein 2-like
chr9_-_94601852 Show fit	27.01	ENSRNOT00000022485	Ngef NCBI RGD Ensembl Show fit	neuronal guanine nucleotide exchange factor
chr7_-_29152442 Show fit	26.74	ENSRNOT00000079774	Mybpc1 NCBI RGD Ensembl Show fit	myosin binding protein C, slow type
chr10_+_48240330 Show fit	26.69	ENSRNOT00000057798	Specc1 NCBI RGD Ensembl Show fit	sperm antigen with calponin homology and coiled-coil domains 1
chr19_-_1074333 Show fit	26.59	ENSRNOT00000017983 ENSRNOT00000086995	Cdh5 NCBI RGD Ensembl Show fit	cadherin 5
chr15_+_33600102 Show fit	26.49	ENSRNOT00000022664	Cmtm5 NCBI RGD Ensembl Show fit	CKLF-like MARVEL transmembrane domain containing 5
chr14_-_92077088 Show fit	26.40	ENSRNOT00000085175	Grb10 NCBI RGD Ensembl Show fit	growth factor receptor bound protein 10
chr1_-_153740905 Show fit	26.28	ENSRNOT00000023239	Prss23 NCBI RGD Ensembl Show fit	protease, serine, 23
chr10_+_38877422 Show fit	26.15	ENSRNOT00000065229 ENSRNOT00000083162	Sept8 NCBI RGD Ensembl Show fit	septin 8
chr10_-_109729019 Show fit	25.95	ENSRNOT00000054959	Ppp1r27 NCBI RGD Ensembl Show fit	protein phosphatase 1, regulatory subunit 27
chr4_+_78168117 Show fit	25.90	ENSRNOT00000010853	Atp6v0e2 NCBI RGD Ensembl Show fit	ATPase, H+ transporting V0 subunit e2
chr1_-_260992291 Show fit	25.85	ENSRNOT00000035415 ENSRNOT00000034758	Slit1 NCBI RGD Ensembl Show fit	slit guidance ligand 1
chr2_+_11658568 Show fit	25.83	ENSRNOT00000076408 ENSRNOT00000076416 ENSRNOT00000076992 ENSRNOT00000075931 ENSRNOT00000076136 ENSRNOT00000076481 ENSRNOT00000076084 ENSRNOT00000076230 ENSRNOT00000076710 ENSRNOT00000076239	Mef2c NCBI RGD Ensembl Show fit	myocyte enhancer factor 2C
chr7_+_59200918 Show fit	25.56	ENSRNOT00000085073	Ptprr NCBI RGD Ensembl Show fit	protein tyrosine phosphatase, receptor type, R
chr3_-_12944494 Show fit	25.51	ENSRNOT00000023172	Mvb12b NCBI RGD Ensembl Show fit	multivesicular body subunit 12B
chr7_+_77899322 Show fit	25.42	ENSRNOT00000006195	Fzd6 NCBI RGD Ensembl Show fit	frizzled class receptor 6
chr1_+_127802978 Show fit	25.35	ENSRNOT00000055877	Adamts17 NCBI RGD Ensembl Show fit	ADAM metallopeptidase with thrombospondin type 1 motif, 17
chr5_+_140923914 Show fit	25.24	ENSRNOT00000020929	Heyl NCBI RGD Ensembl Show fit	hes-related family bHLH transcription factor with YRPW motif-like
chr17_+_47721977 Show fit	25.15	ENSRNOT00000080800	LOC100910792 NCBI RGD Ensembl Show fit	amphiphysin-like
chr8_-_49038169 Show fit	25.11	ENSRNOT00000047303	Phldb1 NCBI RGD Ensembl Show fit	pleckstrin homology-like domain, family B, member 1
chr3_-_123581518 Show fit	24.80	ENSRNOT00000047947	Gfra4 NCBI RGD Ensembl Show fit	GDNF family receptor alpha 4
chr17_+_15924048 Show fit	24.71	ENSRNOT00000050696	Wnk2 NCBI RGD Ensembl Show fit	WNK lysine deficient protein kinase 2
chr10_+_12994683 Show fit	24.63	ENSRNOT00000004702	Hcfc1r1 NCBI RGD Ensembl Show fit	host cell factor C1 regulator 1
chr1_+_266953139 Show fit	24.57	ENSRNOT00000054696	Neurl1 NCBI RGD Ensembl Show fit	neuralized E3 ubiquitin protein ligase 1
chr10_-_88307132 Show fit	24.53	ENSRNOT00000040845	Jup NCBI RGD Ensembl Show fit	junction plakoglobin
chr15_+_48674380 Show fit	24.50	ENSRNOT00000018762	Fbxo16 NCBI RGD Ensembl Show fit	F-box protein 16
chrX_-_111942749 Show fit	24.47	ENSRNOT00000087583	AABR07040840.1 NCBI RGD Ensembl Show fit
chr8_+_116324040 Show fit	24.44	ENSRNOT00000081353	Hyal2 NCBI RGD Ensembl Show fit	hyaluronoglucosaminidase 2
chr10_+_70262361 Show fit	24.40	ENSRNOT00000064625 ENSRNOT00000076973	Unc45b NCBI RGD Ensembl Show fit	unc-45 myosin chaperone B
chr7_-_120027026 Show fit	24.24	ENSRNOT00000011215	Card10 NCBI RGD Ensembl Show fit	caspase recruitment domain family, member 10
chr14_+_87312203 Show fit	24.24	ENSRNOT00000088032	Adcy1 NCBI RGD Ensembl Show fit	adenylate cyclase 1
chr16_-_19894591 Show fit	24.04	ENSRNOT00000085940	Ano8 NCBI RGD Ensembl Show fit	anoctamin 8
chr2_-_185168476 Show fit	24.03	ENSRNOT00000093447	Fam160a1 NCBI RGD Ensembl Show fit	family with sequence similarity 160, member A1
chr12_-_17972737 Show fit	24.02	ENSRNOT00000001783	Fam20c NCBI RGD Ensembl Show fit	FAM20C, golgi associated secretory pathway kinase
chr3_-_105279462 Show fit	23.98	ENSRNOT00000010679	Scg5 NCBI RGD Ensembl Show fit	secretogranin V
chr11_+_16826399 Show fit	23.95	ENSRNOT00000050701	Cxadr NCBI RGD Ensembl Show fit	coxsackie virus and adenovirus receptor
chr10_+_71159869 Show fit	23.84	ENSRNOT00000075977 ENSRNOT00000047427	Hnf1b NCBI RGD Ensembl Show fit	HNF1 homeobox B
chr1_+_72889270 Show fit	23.79	ENSRNOT00000058843 ENSRNOT00000034957	Tnnt1 NCBI RGD Ensembl Show fit	troponin T1, slow skeletal type
chr2_-_229718659 Show fit	23.73	ENSRNOT00000012676	Ugt8 NCBI RGD Ensembl Show fit	UDP glycosyltransferase 8
chrX_-_157286936 Show fit	23.70	ENSRNOT00000078100	Atp2b3 NCBI RGD Ensembl Show fit	ATPase plasma membrane Ca2+ transporting 3
chr6_-_50846965 Show fit	23.67	ENSRNOT00000087300	Slc26a4 NCBI RGD Ensembl Show fit	solute carrier family 26 member 4
chr16_-_22561496 Show fit	23.66	ENSRNOT00000016543	Lpl NCBI RGD Ensembl Show fit	lipoprotein lipase
chr9_+_9961021 Show fit	23.66	ENSRNOT00000075767	Tubb4a NCBI RGD Ensembl Show fit	tubulin, beta 4A class IVa
chr6_+_3657325 Show fit	23.66	ENSRNOT00000010927	Tmem178a NCBI RGD Ensembl Show fit	transmembrane protein 178A
chr19_-_43596801 Show fit	23.46	ENSRNOT00000025625	Fa2h NCBI RGD Ensembl Show fit	fatty acid 2-hydroxylase
chr19_+_784618 Show fit	23.33	ENSRNOT00000014749	Cmtm4 NCBI RGD Ensembl Show fit	CKLF-like MARVEL transmembrane domain containing 4
chr8_+_111210811 Show fit	23.23	ENSRNOT00000011347	Amotl2 NCBI RGD Ensembl Show fit	angiomotin like 2
chr1_-_242083484 Show fit	23.19	ENSRNOT00000065921	Tjp2 NCBI RGD Ensembl Show fit	tight junction protein 2
chr4_-_52350624 Show fit	23.15	ENSRNOT00000060476	Tmem229a NCBI RGD Ensembl Show fit	transmembrane protein 229A
chr9_-_38196273 Show fit	23.04	ENSRNOT00000044452	Dst NCBI RGD Ensembl Show fit	dystonin
chr14_+_79540235 Show fit	22.87	ENSRNOT00000089334	Sorcs2 NCBI RGD Ensembl Show fit	sortilin-related VPS10 domain containing receptor 2
chr2_-_30246010 Show fit	22.78	ENSRNOT00000023900	Mccc2 NCBI RGD Ensembl Show fit	methylcrotonoyl-CoA carboxylase 2
chr4_-_129619142 Show fit	22.70	ENSRNOT00000047453	Lmod3 NCBI RGD Ensembl Show fit	leiomodin 3
chr16_-_49820235 Show fit	22.68	ENSRNOT00000029628	Sorbs2 NCBI RGD Ensembl Show fit	sorbin and SH3 domain containing 2
chrX_+_18489597 Show fit	22.61	ENSRNOT00000059744	LOC681355 NCBI RGD Ensembl Show fit	similar to potassium channel tetramerisation domain containing 12b
chr1_+_79989019 Show fit	22.57	ENSRNOT00000020428	Dmpk NCBI RGD Ensembl Show fit	dystrophia myotonica-protein kinase
chr9_-_45505767 Show fit	22.54	ENSRNOT00000033964	Lonrf2 NCBI RGD Ensembl Show fit	LON peptidase N-terminal domain and ring finger 2
chr6_+_50528823 Show fit	22.53	ENSRNOT00000008321	Lamb1 NCBI RGD Ensembl Show fit	laminin subunit beta 1
chr20_-_47910375 Show fit	22.51	ENSRNOT00000000348	Sobp NCBI RGD Ensembl Show fit	sine oculis binding protein homolog
chr14_+_99529284 Show fit	22.49	ENSRNOT00000006897 ENSRNOT00000067134	Vstm2a NCBI RGD Ensembl Show fit	V-set and transmembrane domain containing 2A
chr10_-_51669297 Show fit	22.47	ENSRNOT00000071595	Arhgap44 NCBI RGD Ensembl Show fit	Rho GTPase activating protein 44
chr16_+_2670618 Show fit	22.46	ENSRNOT00000030102	Il17rd NCBI RGD Ensembl Show fit	interleukin 17 receptor D
chr5_-_21345805 Show fit	22.37	ENSRNOT00000081296 ENSRNOT00000007802	Car8 NCBI RGD Ensembl Show fit	carbonic anhydrase 8
chr11_+_69739384 Show fit	22.29	ENSRNOT00000016340	Kalrn NCBI RGD Ensembl Show fit	kalirin, RhoGEF kinase
chr1_+_265298868 Show fit	22.28	ENSRNOT00000023278	Dpcd NCBI RGD Ensembl Show fit	deleted in primary ciliary dyskinesia
chr7_+_141973553 Show fit	22.08	ENSRNOT00000052075	Mettl7a NCBI RGD Ensembl Show fit	methyltransferase like 7A
chr14_+_66598259 Show fit	21.98	ENSRNOT00000049743	Kcnip4 NCBI RGD Ensembl Show fit	potassium voltage-gated channel interacting protein 4
chr7_+_29435444 Show fit	21.95	ENSRNOT00000008613	Slc5a8 NCBI RGD Ensembl Show fit	solute carrier family 5 member 8
chr7_+_145117951 Show fit	21.80	ENSRNOT00000055272	Pde1b NCBI RGD Ensembl Show fit	phosphodiesterase 1B
chr8_+_128972311 Show fit	21.73	ENSRNOT00000025460	Myrip NCBI RGD Ensembl Show fit	myosin VIIA and Rab interacting protein
chr4_-_82202096 Show fit	21.72	ENSRNOT00000081824	LOC100912608 NCBI RGD Ensembl Show fit	homeobox protein Hox-A10-like
chr14_+_63095720 Show fit	21.67	ENSRNOT00000006071	Ppargc1a NCBI RGD Ensembl Show fit	PPARG coactivator 1 alpha
chr5_+_61657507 Show fit	21.61	ENSRNOT00000013228	Tmod1 NCBI RGD Ensembl Show fit	tropomodulin 1
chr10_+_55275411 Show fit	21.59	ENSRNOT00000065895	Myh10 NCBI RGD Ensembl Show fit	myosin heavy chain 10
chr13_+_75111778 Show fit	21.59	ENSRNOT00000006924	Tp53i3 NCBI RGD Ensembl Show fit	tumor protein p53 inducible protein 3
chr2_+_45104305 Show fit	21.57	ENSRNOT00000014559	Esm1 NCBI RGD Ensembl Show fit	endothelial cell-specific molecule 1
chr10_-_47724499 Show fit	21.54	ENSRNOT00000085011	Rnf112 NCBI RGD Ensembl Show fit	ring finger protein 112
chr1_-_219422268 Show fit	21.53	ENSRNOT00000025092	Carns1 NCBI RGD Ensembl Show fit	carnosine synthase 1
chr5_-_40237591 Show fit	21.46	ENSRNOT00000011393	Fut9 NCBI RGD Ensembl Show fit	fucosyltransferase 9
chr10_+_86669233 Show fit	21.45	ENSRNOT00000012340	Thra NCBI RGD Ensembl Show fit	thyroid hormone receptor alpha
chr2_-_46476203 Show fit	21.21	ENSRNOT00000015217	Ndufs4 NCBI RGD Ensembl Show fit	NADH:ubiquinone oxidoreductase subunit S4
chr4_-_64831233 Show fit	21.14	ENSRNOT00000079285	Dgki NCBI RGD Ensembl Show fit	diacylglycerol kinase, iota
chr3_-_72219246 Show fit	20.88	ENSRNOT00000009903	Smtnl1 NCBI RGD Ensembl Show fit	smoothelin-like 1
chrX_-_136807885 Show fit	20.88	ENSRNOT00000010325	Igsf1 NCBI RGD Ensembl Show fit	immunoglobulin superfamily, member 1
chr1_-_165680176 Show fit	20.82	ENSRNOT00000025245 ENSRNOT00000082697	Plekhb1 NCBI RGD Ensembl Show fit	pleckstrin homology domain containing B1

Network of associatons between targets according to the STRING database.

First level regulatory network of Id4

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
25.2	226.4	GO:0001766	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
18.6	92.9	GO:0002159	desmosome assembly(GO:0002159)
15.7	62.8	GO:1904204	regulation of skeletal muscle hypertrophy(GO:1904204)
15.6	46.8	GO:0003065	positive regulation of heart rate by epinephrine(GO:0003065)
14.6	43.9	GO:0021678	third ventricle development(GO:0021678)
14.6	43.8	GO:0046340	diacylglycerol catabolic process(GO:0046340)
14.5	58.0	GO:0031179	peptide modification(GO:0031179)
13.4	13.4	GO:1904000	positive regulation of eating behavior(GO:1904000)
13.4	66.9	GO:0098989	NMDA selective glutamate receptor signaling pathway(GO:0098989)
13.0	38.9	GO:0071529	cementum mineralization(GO:0071529)
12.7	63.3	GO:2001016	positive regulation of skeletal muscle cell differentiation(GO:2001016)
12.2	36.6	GO:1902304	positive regulation of potassium ion export(GO:1902304)
11.8	35.5	GO:2001205	negative regulation of osteoclast development(GO:2001205)
11.5	57.6	GO:1900194	negative regulation of oocyte maturation(GO:1900194)
11.2	33.5	GO:0006480	N-terminal protein amino acid methylation(GO:0006480)
11.0	33.1	GO:0010133	proline catabolic process to glutamate(GO:0010133)
10.8	21.7	GO:1904638	response to resveratrol(GO:1904638)
10.7	53.4	GO:1903385	regulation of homophilic cell adhesion(GO:1903385)
10.4	41.5	GO:0032349	positive regulation of aldosterone metabolic process(GO:0032346) positive regulation of aldosterone biosynthetic process(GO:0032349)
10.3	31.0	GO:0044208	'de novo' AMP biosynthetic process(GO:0044208)
10.3	41.1	GO:0036309	protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
10.2	71.2	GO:0010890	positive regulation of sequestering of triglyceride(GO:0010890)
10.1	40.6	GO:0051944	peptidyl-cysteine methylation(GO:0018125) positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
10.1	40.2	GO:0051725	protein de-ADP-ribosylation(GO:0051725)
10.0	30.1	GO:0019417	sulfur oxidation(GO:0019417)
9.9	39.7	GO:0098886	modification of dendritic spine(GO:0098886)
9.7	29.2	GO:0010725	regulation of primitive erythrocyte differentiation(GO:0010725)
9.5	57.1	GO:1903059	regulation of protein lipidation(GO:1903059)
9.5	28.5	GO:0098528	skeletal muscle fiber differentiation(GO:0098528)
9.5	123.0	GO:0032836	glomerular basement membrane development(GO:0032836)
9.4	18.9	GO:0090427	activation of meiosis(GO:0090427)
9.2	46.1	GO:0035106	operant conditioning(GO:0035106)
9.2	27.5	GO:0032972	regulation of muscle filament sliding speed(GO:0032972)
8.9	107.4	GO:0001778	plasma membrane repair(GO:0001778)
8.9	44.4	GO:0038044	transforming growth factor-beta secretion(GO:0038044)
8.8	35.1	GO:0003350	pulmonary myocardium development(GO:0003350)
8.6	42.9	GO:0014722	regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
8.5	25.4	GO:0035880	embryonic nail plate morphogenesis(GO:0035880)
8.4	25.2	GO:0090038	negative regulation of protein kinase C signaling(GO:0090038)
8.3	16.6	GO:0032902	nerve growth factor production(GO:0032902)
8.3	24.8	GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
8.2	40.8	GO:0050828	regulation of liquid surface tension(GO:0050828)
8.1	97.7	GO:0071316	cellular response to nicotine(GO:0071316)
8.0	16.1	GO:0032971	regulation of muscle filament sliding(GO:0032971)
8.0	24.0	GO:0097187	odontoblast differentiation(GO:0071895) dentinogenesis(GO:0097187)
8.0	23.9	GO:0098904	regulation of AV node cell action potential(GO:0098904)
7.9	23.8	GO:0061228	mesonephros morphogenesis(GO:0061206) mesonephric nephron development(GO:0061215) mesonephric nephron morphogenesis(GO:0061228) mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis(GO:0061235) regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061295) negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061296) mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:1901146)
7.9	31.7	GO:0061107	seminal vesicle development(GO:0061107)
7.9	23.8	GO:0031444	slow-twitch skeletal muscle fiber contraction(GO:0031444)
7.9	23.7	GO:0006682	galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
7.8	54.7	GO:0060842	arterial endothelial cell differentiation(GO:0060842)
7.6	22.8	GO:0006552	leucine catabolic process(GO:0006552)
7.5	22.5	GO:0021812	neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
7.3	73.4	GO:0071688	striated muscle myosin thick filament assembly(GO:0071688)
7.2	14.4	GO:0045819	positive regulation of glycogen catabolic process(GO:0045819)
7.2	28.6	GO:1904428	negative regulation of tubulin deacetylation(GO:1904428)
7.2	21.5	GO:0017055	negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
7.1	28.5	GO:0003199	endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
7.1	21.2	GO:0044209	AMP salvage(GO:0044209)
7.0	28.1	GO:0032849	positive regulation of cellular pH reduction(GO:0032849)
7.0	27.9	GO:1901423	response to benzene(GO:1901423)
6.7	6.7	GO:1903903	regulation of establishment of T cell polarity(GO:1903903)
6.6	19.8	GO:0015938	coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034) fatty-acyl-CoA catabolic process(GO:0036115)
6.5	25.8	GO:0021834	chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration(GO:0021834)
6.3	31.7	GO:0007621	negative regulation of female receptivity(GO:0007621)
6.3	18.8	GO:0097089	methyl-branched fatty acid metabolic process(GO:0097089)
6.1	42.9	GO:0002238	response to molecule of fungal origin(GO:0002238)
6.0	18.1	GO:0021564	vagus nerve development(GO:0021564)
5.9	17.6	GO:0030327	prenylated protein catabolic process(GO:0030327)
5.8	17.3	GO:0014873	response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
5.8	11.5	GO:0045054	constitutive secretory pathway(GO:0045054)
5.5	27.3	GO:0001582	detection of chemical stimulus involved in sensory perception of sweet taste(GO:0001582)
5.4	10.8	GO:0032423	regulation of mismatch repair(GO:0032423)
5.4	21.6	GO:1902202	regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
5.4	69.6	GO:0006527	arginine catabolic process(GO:0006527)
5.3	15.8	GO:0045959	negative regulation of complement activation, classical pathway(GO:0045959)
5.2	15.7	GO:0045163	clustering of voltage-gated potassium channels(GO:0045163)
5.1	25.3	GO:0046959	habituation(GO:0046959)
5.0	30.2	GO:0035331	negative regulation of hippo signaling(GO:0035331)
5.0	14.9	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
5.0	14.9	GO:0071691	cardiac muscle thin filament assembly(GO:0071691)
4.9	24.4	GO:0039663	fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
4.9	34.2	GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
4.9	14.6	GO:0070084	protein initiator methionine removal(GO:0070084)
4.8	4.8	GO:0021577	hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
4.7	75.0	GO:0021860	pyramidal neuron development(GO:0021860)
4.6	41.7	GO:0042421	norepinephrine biosynthetic process(GO:0042421)
4.6	13.8	GO:0006116	NADH oxidation(GO:0006116)
4.5	27.0	GO:0061002	negative regulation of dendritic spine morphogenesis(GO:0061002)
4.5	22.5	GO:0070346	positive regulation of fat cell proliferation(GO:0070346)
4.5	49.1	GO:0031914	negative regulation of synaptic plasticity(GO:0031914)
4.4	31.0	GO:0016199	axon midline choice point recognition(GO:0016199)
4.4	26.6	GO:1901552	positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
4.4	17.6	GO:0014878	response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
4.4	17.4	GO:0002074	extraocular skeletal muscle development(GO:0002074)
4.4	13.1	GO:0034769	basement membrane disassembly(GO:0034769)
4.3	42.9	GO:0071985	multivesicular body sorting pathway(GO:0071985)
4.3	12.8	GO:0032696	negative regulation of interleukin-13 production(GO:0032696)
4.3	17.1	GO:1904045	cellular response to aldosterone(GO:1904045)
4.2	16.8	GO:2000546	positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
4.1	8.3	GO:0098915	membrane repolarization during ventricular cardiac muscle cell action potential(GO:0098915)
4.1	28.8	GO:0015705	iodide transport(GO:0015705)
4.1	16.4	GO:0016332	establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
4.1	12.2	GO:0045900	negative regulation of translational elongation(GO:0045900)
4.0	16.2	GO:1903225	negative regulation of endodermal cell differentiation(GO:1903225)
4.0	7.9	GO:0038109	Kit signaling pathway(GO:0038109)
3.9	19.7	GO:2000553	positive regulation of T-helper 2 cell cytokine production(GO:2000553)
3.9	23.5	GO:0032286	central nervous system myelin maintenance(GO:0032286)
3.9	11.7	GO:0018199	peptidyl-glutamine modification(GO:0018199)
3.8	38.5	GO:0006657	CDP-choline pathway(GO:0006657)
3.8	19.2	GO:1902732	positive regulation of chondrocyte proliferation(GO:1902732)
3.8	26.4	GO:0045719	negative regulation of glycogen biosynthetic process(GO:0045719)
3.7	18.7	GO:0010966	regulation of phosphate transport(GO:0010966)
3.7	11.2	GO:1903847	regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
3.7	11.0	GO:0061732	mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
3.6	14.5	GO:0015888	thiamine transport(GO:0015888)
3.6	18.0	GO:0009449	gamma-aminobutyric acid biosynthetic process(GO:0009449)
3.6	25.2	GO:0072014	proximal tubule development(GO:0072014)
3.5	31.9	GO:0030953	astral microtubule organization(GO:0030953)
3.5	10.4	GO:0015755	fructose transport(GO:0015755)
3.4	17.2	GO:0030309	poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
3.4	23.9	GO:0048251	elastic fiber assembly(GO:0048251)
3.4	23.7	GO:1990034	calcium ion export from cell(GO:1990034)
3.4	10.1	GO:0042357	thiamine diphosphate metabolic process(GO:0042357)
3.3	6.7	GO:1901187	regulation of ephrin receptor signaling pathway(GO:1901187)
3.3	128.9	GO:0035640	exploration behavior(GO:0035640)
3.2	22.7	GO:0051694	pointed-end actin filament capping(GO:0051694)
3.2	6.5	GO:0010980	regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
3.2	12.9	GO:0072086	specification of loop of Henle identity(GO:0072086)
3.2	15.9	GO:0071816	tail-anchored membrane protein insertion into ER membrane(GO:0071816)
3.2	95.1	GO:0010107	potassium ion import(GO:0010107)
3.1	12.6	GO:0072139	glomerular parietal epithelial cell differentiation(GO:0072139)
3.1	6.2	GO:0052564	response to immune response of other organism involved in symbiotic interaction(GO:0052564) response to host immune response(GO:0052572)
3.1	65.0	GO:0070831	basement membrane assembly(GO:0070831)
3.1	52.2	GO:0035994	response to muscle stretch(GO:0035994)
3.0	12.1	GO:0001757	somite specification(GO:0001757)
3.0	111.5	GO:0003009	skeletal muscle contraction(GO:0003009)
3.0	32.9	GO:0016322	neuron remodeling(GO:0016322)
3.0	38.9	GO:0030388	fructose 1,6-bisphosphate metabolic process(GO:0030388)
3.0	53.7	GO:0002026	regulation of the force of heart contraction(GO:0002026)
3.0	20.9	GO:0048227	plasma membrane to endosome transport(GO:0048227)
3.0	14.9	GO:0060385	axonogenesis involved in innervation(GO:0060385)
3.0	8.9	GO:0031394	positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
2.9	14.7	GO:0010626	negative regulation of Schwann cell proliferation(GO:0010626)
2.9	17.6	GO:0006102	isocitrate metabolic process(GO:0006102)
2.9	41.0	GO:0031340	positive regulation of vesicle fusion(GO:0031340)
2.9	5.7	GO:0046878	positive regulation of saliva secretion(GO:0046878)
2.8	76.0	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
2.8	5.6	GO:0061741	vacuolar transmembrane transport(GO:0034486) chaperone-mediated protein transport involved in chaperone-mediated autophagy(GO:0061741)
2.8	11.2	GO:0010728	regulation of hydrogen peroxide biosynthetic process(GO:0010728)
2.8	11.2	GO:0036324	vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
2.8	33.1	GO:0046069	cGMP catabolic process(GO:0046069)
2.7	32.8	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
2.7	32.6	GO:0055003	cardiac myofibril assembly(GO:0055003)
2.7	13.4	GO:0034553	respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
2.6	7.9	GO:0009912	auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
2.6	5.3	GO:1902527	positive regulation of protein monoubiquitination(GO:1902527)
2.6	7.9	GO:0048560	establishment of anatomical structure orientation(GO:0048560)
2.6	7.8	GO:1902269	positive regulation of polyamine transmembrane transport(GO:1902269)
2.6	7.7	GO:0015864	pyrimidine nucleoside transport(GO:0015864)
2.6	7.7	GO:0009758	carbohydrate utilization(GO:0009758)
2.5	12.7	GO:0021913	regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
2.5	19.8	GO:0019388	galactose catabolic process(GO:0019388)
2.4	12.1	GO:0021636	trigeminal nerve morphogenesis(GO:0021636) trigeminal nerve structural organization(GO:0021637) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
2.4	7.2	GO:2000853	negative regulation of corticosterone secretion(GO:2000853)
2.4	16.5	GO:0071000	response to magnetism(GO:0071000)
2.3	7.0	GO:1904708	granulosa cell apoptotic process(GO:1904700) regulation of granulosa cell apoptotic process(GO:1904708)
2.3	18.5	GO:0097211	response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
2.3	9.2	GO:0031642	negative regulation of myelination(GO:0031642)
2.3	9.2	GO:0003164	His-Purkinje system development(GO:0003164)
2.3	4.5	GO:2000370	positive regulation of clathrin-mediated endocytosis(GO:2000370)
2.2	20.2	GO:0045162	clustering of voltage-gated sodium channels(GO:0045162)
2.2	11.1	GO:0044691	tooth eruption(GO:0044691)
2.2	12.9	GO:0032439	endosome localization(GO:0032439)
2.2	8.6	GO:0097069	cellular response to thyroxine stimulus(GO:0097069)
2.1	4.3	GO:0031630	regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
2.1	8.6	GO:0019254	carnitine metabolic process, CoA-linked(GO:0019254)
2.1	2.1	GO:0006701	progesterone biosynthetic process(GO:0006701)
2.1	46.6	GO:0097503	sialylation(GO:0097503)
2.1	12.6	GO:0001661	conditioned taste aversion(GO:0001661)
2.1	14.6	GO:2000346	negative regulation of hepatocyte proliferation(GO:2000346)
2.1	12.5	GO:0035166	post-embryonic hemopoiesis(GO:0035166)
2.1	35.2	GO:0031581	hemidesmosome assembly(GO:0031581)
2.1	8.2	GO:0016998	cell wall macromolecule catabolic process(GO:0016998)
2.0	7.8	GO:2000259	positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
2.0	7.8	GO:0072070	loop of Henle development(GO:0072070)
1.9	52.6	GO:1903831	acetylcholine receptor signaling pathway(GO:0095500) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
1.9	23.1	GO:0071340	skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
1.9	9.6	GO:0003105	negative regulation of glomerular filtration(GO:0003105)
1.9	5.7	GO:1990523	bone regeneration(GO:1990523)
1.9	13.2	GO:0098828	positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
1.9	15.0	GO:0060481	lobar bronchus epithelium development(GO:0060481) lobar bronchus development(GO:0060482)
1.9	20.6	GO:0006670	sphingosine metabolic process(GO:0006670)
1.8	7.2	GO:0060164	regulation of timing of neuron differentiation(GO:0060164)
1.8	17.9	GO:0021796	cerebral cortex regionalization(GO:0021796)
1.8	19.6	GO:1902902	negative regulation of autophagosome assembly(GO:1902902)
1.8	7.1	GO:0009138	pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
1.8	24.6	GO:0090129	positive regulation of synapse maturation(GO:0090129)
1.7	10.5	GO:0021633	optic nerve structural organization(GO:0021633)
1.7	67.3	GO:0009250	glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
1.7	6.8	GO:0007172	signal complex assembly(GO:0007172)
1.7	28.8	GO:0016486	peptide hormone processing(GO:0016486)
1.7	6.8	GO:0019464	glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
1.7	8.4	GO:0032532	regulation of microvillus length(GO:0032532)
1.7	21.5	GO:0015693	magnesium ion transport(GO:0015693)
1.6	69.6	GO:0048488	synaptic vesicle endocytosis(GO:0048488)
1.6	6.3	GO:2001199	negative regulation of dendritic cell differentiation(GO:2001199)
1.6	12.5	GO:0046710	GDP metabolic process(GO:0046710)
1.6	12.5	GO:0097688	glutamate receptor clustering(GO:0097688)
1.6	4.7	GO:0045578	negative regulation of B cell differentiation(GO:0045578)
1.5	15.4	GO:0021891	olfactory bulb interneuron development(GO:0021891)
1.5	21.5	GO:0036065	fucosylation(GO:0036065)
1.5	16.7	GO:0019934	cGMP-mediated signaling(GO:0019934)
1.5	24.2	GO:0007250	activation of NF-kappaB-inducing kinase activity(GO:0007250)
1.5	12.1	GO:0051583	dopamine uptake involved in synaptic transmission(GO:0051583) catecholamine uptake involved in synaptic transmission(GO:0051934)
1.5	4.5	GO:0042489	negative regulation of odontogenesis of dentin-containing tooth(GO:0042489)
1.5	6.0	GO:0061314	regulation of cell differentiation involved in embryonic placenta development(GO:0060800) Notch signaling involved in heart development(GO:0061314)
1.5	9.0	GO:0051534	negative regulation of NFAT protein import into nucleus(GO:0051534)
1.5	9.0	GO:0046874	quinolinate metabolic process(GO:0046874)
1.5	33.7	GO:0001553	luteinization(GO:0001553)
1.5	5.8	GO:0070272	proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
1.4	2.9	GO:0002426	immunoglobulin production in mucosal tissue(GO:0002426)
1.4	12.9	GO:0018026	peptidyl-lysine monomethylation(GO:0018026)
1.4	14.1	GO:0030432	peristalsis(GO:0030432)
1.4	15.5	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
1.4	7.0	GO:0071677	positive regulation of mononuclear cell migration(GO:0071677)
1.4	12.6	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
1.4	5.6	GO:0046951	ketone body biosynthetic process(GO:0046951)
1.4	8.3	GO:0030174	regulation of DNA-dependent DNA replication initiation(GO:0030174)
1.4	4.1	GO:0006649	phospholipid transfer to membrane(GO:0006649)
1.4	12.3	GO:0043922	negative regulation by host of viral transcription(GO:0043922)
1.4	10.9	GO:0015760	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
1.4	5.4	GO:0042998	positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
1.3	21.4	GO:0071850	mitotic cell cycle arrest(GO:0071850)
1.3	9.3	GO:0060157	urinary bladder development(GO:0060157)
1.3	6.5	GO:1990564	protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
1.3	10.4	GO:0051182	coenzyme transport(GO:0051182)
1.3	5.2	GO:0061588	calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
1.3	5.2	GO:0002184	cytoplasmic translational termination(GO:0002184)
1.3	30.9	GO:0043153	entrainment of circadian clock by photoperiod(GO:0043153)
1.3	7.5	GO:0051136	regulation of NK T cell differentiation(GO:0051136)
1.2	5.0	GO:0098963	dendritic transport of ribonucleoprotein complex(GO:0098961) dendritic transport of messenger ribonucleoprotein complex(GO:0098963) anterograde dendritic transport of messenger ribonucleoprotein complex(GO:0098964)
1.2	9.9	GO:1902414	protein localization to cell junction(GO:1902414)
1.2	19.6	GO:0035313	wound healing, spreading of epidermal cells(GO:0035313)
1.2	19.4	GO:2000651	positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
1.2	3.6	GO:0006421	asparaginyl-tRNA aminoacylation(GO:0006421)
1.2	19.2	GO:0071257	cellular response to electrical stimulus(GO:0071257)
1.2	4.8	GO:0035772	interleukin-13-mediated signaling pathway(GO:0035772)
1.2	3.6	GO:0019086	late viral transcription(GO:0019086)
1.2	7.1	GO:0036465	synaptic vesicle recycling(GO:0036465)
1.2	11.6	GO:1990440	positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
1.2	2.3	GO:0090118	receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118)
1.1	8.0	GO:0060050	positive regulation of protein glycosylation(GO:0060050) Golgi disassembly(GO:0090166)
1.1	6.6	GO:0010649	regulation of cell communication by electrical coupling(GO:0010649)
1.1	4.4	GO:0090611	ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
1.1	3.3	GO:0021816	lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
1.1	5.5	GO:0038180	nerve growth factor signaling pathway(GO:0038180)
1.1	4.4	GO:1990375	baculum development(GO:1990375)
1.1	42.3	GO:0018149	peptide cross-linking(GO:0018149)
1.1	3.2	GO:0000965	mitochondrial RNA 3'-end processing(GO:0000965)
1.1	16.2	GO:0006517	protein deglycosylation(GO:0006517)
1.1	23.7	GO:0045671	negative regulation of osteoclast differentiation(GO:0045671)
1.1	11.8	GO:0045723	positive regulation of fatty acid biosynthetic process(GO:0045723)
1.1	1.1	GO:0071910	determination of pancreatic left/right asymmetry(GO:0035469) determination of liver left/right asymmetry(GO:0071910)
1.1	16.9	GO:0030150	protein import into mitochondrial matrix(GO:0030150)
1.0	14.6	GO:0032060	bleb assembly(GO:0032060)
1.0	14.6	GO:0090557	establishment of endothelial intestinal barrier(GO:0090557)
1.0	23.7	GO:0061049	physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
1.0	3.1	GO:0006574	valine catabolic process(GO:0006574)
1.0	3.0	GO:0006045	N-acetylglucosamine biosynthetic process(GO:0006045) N-acetylneuraminate biosynthetic process(GO:0046380) glucosamine-containing compound biosynthetic process(GO:1901073)
1.0	36.4	GO:0006730	one-carbon metabolic process(GO:0006730)
1.0	14.1	GO:0045838	positive regulation of membrane potential(GO:0045838)
1.0	12.9	GO:2001256	regulation of store-operated calcium entry(GO:2001256)
1.0	4.0	GO:0030043	actin filament fragmentation(GO:0030043)
1.0	8.9	GO:0000338	protein deneddylation(GO:0000338)
1.0	6.9	GO:0006627	protein processing involved in protein targeting to mitochondrion(GO:0006627)
1.0	6.9	GO:0032230	positive regulation of synaptic transmission, GABAergic(GO:0032230)
1.0	10.5	GO:0007028	cytoplasm organization(GO:0007028)
1.0	20.0	GO:0014002	astrocyte development(GO:0014002)
0.9	16.0	GO:0032981	NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.9	7.4	GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.9	9.3	GO:0003084	positive regulation of systemic arterial blood pressure(GO:0003084)
0.9	8.1	GO:0007258	JUN phosphorylation(GO:0007258)
0.9	4.5	GO:0022010	central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.9	3.6	GO:1901662	phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662)
0.9	2.7	GO:0061146	Peyer's patch morphogenesis(GO:0061146)
0.9	32.6	GO:1900047	negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.9	4.4	GO:2001198	plasma cell differentiation(GO:0002317) regulation of dendritic cell differentiation(GO:2001198) positive regulation of dendritic cell differentiation(GO:2001200)
0.9	14.8	GO:0060219	camera-type eye photoreceptor cell differentiation(GO:0060219)
0.9	8.7	GO:0033623	regulation of integrin activation(GO:0033623)
0.8	21.2	GO:0010226	response to lithium ion(GO:0010226)
0.8	6.8	GO:0010919	regulation of inositol phosphate biosynthetic process(GO:0010919) positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.8	16.0	GO:0032274	gonadotropin secretion(GO:0032274)
0.8	5.9	GO:1900113	negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.8	0.8	GO:0043589	skin morphogenesis(GO:0043589)
0.8	17.4	GO:0042347	negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.8	5.0	GO:1901142	insulin metabolic process(GO:1901142)
0.8	5.8	GO:0035810	positive regulation of urine volume(GO:0035810)
0.8	12.4	GO:0034315	regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.8	4.1	GO:0002568	somatic diversification of T cell receptor genes(GO:0002568) somatic recombination of T cell receptor gene segments(GO:0002681) T cell receptor V(D)J recombination(GO:0033153)
0.8	25.9	GO:0015991	energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991)
0.8	6.4	GO:0031848	protection from non-homologous end joining at telomere(GO:0031848)
0.8	12.0	GO:0048266	behavioral response to pain(GO:0048266)
0.8	20.9	GO:0045907	positive regulation of vasoconstriction(GO:0045907)
0.8	6.9	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.8	38.3	GO:0045739	positive regulation of DNA repair(GO:0045739)
0.8	10.7	GO:0030497	fatty acid elongation(GO:0030497)
0.8	20.6	GO:0031103	axon regeneration(GO:0031103)
0.8	4.5	GO:0006776	vitamin A metabolic process(GO:0006776)
0.7	21.5	GO:0071158	positive regulation of cell cycle arrest(GO:0071158)
0.7	22.9	GO:0035987	endodermal cell differentiation(GO:0035987)
0.7	1.5	GO:2001137	positive regulation of endocytic recycling(GO:2001137)
0.7	2.9	GO:0014874	response to stimulus involved in regulation of muscle adaptation(GO:0014874)
0.7	11.6	GO:0006622	protein targeting to lysosome(GO:0006622)
0.7	48.5	GO:1901379	regulation of potassium ion transmembrane transport(GO:1901379)
0.7	1.4	GO:0030321	transepithelial chloride transport(GO:0030321)
0.7	7.2	GO:0008343	adult feeding behavior(GO:0008343)
0.7	10.6	GO:0060384	innervation(GO:0060384)
0.7	36.0	GO:0045445	myoblast differentiation(GO:0045445)
0.7	7.0	GO:0002098	tRNA wobble uridine modification(GO:0002098)
0.7	8.3	GO:0010996	response to auditory stimulus(GO:0010996)
0.7	15.9	GO:0035025	positive regulation of Rho protein signal transduction(GO:0035025)
0.7	10.3	GO:0001709	cell fate determination(GO:0001709)
0.7	15.1	GO:0030517	negative regulation of axon extension(GO:0030517)
0.7	9.6	GO:0021794	thalamus development(GO:0021794)
0.7	33.4	GO:0000186	activation of MAPKK activity(GO:0000186)
0.7	20.4	GO:0006303	double-strand break repair via nonhomologous end joining(GO:0006303)
0.7	3.4	GO:0070125	mitochondrial translational elongation(GO:0070125)
0.7	20.2	GO:0006779	porphyrin-containing compound biosynthetic process(GO:0006779)
0.7	16.2	GO:0045746	negative regulation of Notch signaling pathway(GO:0045746)
0.7	12.1	GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742) positive regulation of ERBB signaling pathway(GO:1901186)
0.7	6.5	GO:2000300	regulation of synaptic vesicle exocytosis(GO:2000300)
0.6	12.2	GO:0055078	sodium ion homeostasis(GO:0055078)
0.6	5.8	GO:0098719	sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.6	3.2	GO:0033572	transferrin transport(GO:0033572)
0.6	1.3	GO:0021938	smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938) spinal cord ventral commissure morphogenesis(GO:0021965)
0.6	16.0	GO:0055013	cardiac muscle cell development(GO:0055013)
0.6	7.6	GO:0060575	intestinal epithelial cell differentiation(GO:0060575)
0.6	12.0	GO:0014003	oligodendrocyte development(GO:0014003)
0.6	56.2	GO:0050807	regulation of synapse organization(GO:0050807)
0.6	16.6	GO:0042058	regulation of epidermal growth factor receptor signaling pathway(GO:0042058)
0.6	18.2	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.6	39.1	GO:1902600	hydrogen ion transmembrane transport(GO:1902600)
0.6	3.6	GO:0035524	proline transmembrane transport(GO:0035524)
0.6	12.3	GO:0001755	neural crest cell migration(GO:0001755)
0.6	15.1	GO:0040018	positive regulation of multicellular organism growth(GO:0040018)
0.6	5.1	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.6	3.3	GO:0048496	maintenance of organ identity(GO:0048496)
0.5	3.3	GO:0015684	ferrous iron transport(GO:0015684) ferrous iron transmembrane transport(GO:1903874)
0.5	7.0	GO:0042407	cristae formation(GO:0042407)
0.5	8.4	GO:0001675	acrosome assembly(GO:0001675)
0.5	2.0	GO:0010994	regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
0.5	6.6	GO:0031115	negative regulation of microtubule polymerization(GO:0031115)
0.5	12.6	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.5	14.4	GO:0030199	collagen fibril organization(GO:0030199)
0.5	2.0	GO:0072386	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.5	6.8	GO:0010591	regulation of lamellipodium assembly(GO:0010591)
0.5	2.9	GO:0015886	heme transport(GO:0015886)
0.5	4.3	GO:2000272	negative regulation of receptor activity(GO:2000272)
0.5	7.1	GO:0051354	negative regulation of oxidoreductase activity(GO:0051354)
0.5	10.7	GO:2000171	negative regulation of dendrite development(GO:2000171)
0.5	6.0	GO:0045109	intermediate filament organization(GO:0045109)
0.4	13.3	GO:0018345	protein palmitoylation(GO:0018345)
0.4	43.4	GO:0031032	actomyosin structure organization(GO:0031032)
0.4	6.6	GO:0006691	leukotriene metabolic process(GO:0006691)
0.4	5.2	GO:0008090	retrograde axonal transport(GO:0008090)
0.4	18.8	GO:0002028	regulation of sodium ion transport(GO:0002028)
0.4	6.8	GO:1900037	regulation of cellular response to hypoxia(GO:1900037)
0.4	16.8	GO:0010507	negative regulation of autophagy(GO:0010507)
0.4	3.3	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.4	17.3	GO:0007416	synapse assembly(GO:0007416)
0.4	76.4	GO:0007517	muscle organ development(GO:0007517)
0.4	0.4	GO:0061046	foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492) regulation of branching involved in lung morphogenesis(GO:0061046) positive regulation of branching involved in lung morphogenesis(GO:0061047)
0.4	3.5	GO:0007196	adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.4	5.0	GO:0034063	stress granule assembly(GO:0034063)
0.4	6.5	GO:0045956	positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.4	10.2	GO:0035428	hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.4	8.3	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.4	23.3	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.4	5.2	GO:0035767	endothelial cell chemotaxis(GO:0035767)
0.4	8.9	GO:0007212	dopamine receptor signaling pathway(GO:0007212)
0.4	18.4	GO:0061077	chaperone-mediated protein folding(GO:0061077)
0.4	21.5	GO:1901607	alpha-amino acid biosynthetic process(GO:1901607)
0.4	10.5	GO:0043462	regulation of ATPase activity(GO:0043462)
0.3	5.6	GO:0006743	ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.3	30.3	GO:1902476	chloride transmembrane transport(GO:1902476)
0.3	2.0	GO:0003334	keratinocyte development(GO:0003334)
0.3	2.0	GO:0048672	positive regulation of collateral sprouting(GO:0048672)
0.3	7.5	GO:0001893	maternal placenta development(GO:0001893)
0.3	1.6	GO:0021554	optic nerve development(GO:0021554)
0.3	9.2	GO:0006829	zinc II ion transport(GO:0006829)
0.3	4.0	GO:0006390	transcription from mitochondrial promoter(GO:0006390)
0.3	3.7	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.3	12.8	GO:0001541	ovarian follicle development(GO:0001541)
0.3	0.9	GO:1901838	positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.3	4.7	GO:1990126	retrograde transport, endosome to plasma membrane(GO:1990126)
0.3	2.3	GO:0043508	negative regulation of JUN kinase activity(GO:0043508)
0.3	7.7	GO:0034340	response to type I interferon(GO:0034340)
0.3	1.9	GO:0006689	ganglioside catabolic process(GO:0006689)
0.3	21.7	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.3	6.3	GO:0048662	negative regulation of smooth muscle cell proliferation(GO:0048662)
0.3	1.3	GO:0043649	dicarboxylic acid catabolic process(GO:0043649)
0.3	12.4	GO:0046677	response to antibiotic(GO:0046677)
0.3	7.0	GO:0021762	substantia nigra development(GO:0021762)
0.2	7.9	GO:0009409	response to cold(GO:0009409)
0.2	8.6	GO:0006506	GPI anchor biosynthetic process(GO:0006506)
0.2	10.8	GO:0080171	lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.2	4.3	GO:1904355	positive regulation of telomere capping(GO:1904355)
0.2	13.8	GO:0010923	negative regulation of phosphatase activity(GO:0010923)
0.2	7.2	GO:0032024	positive regulation of insulin secretion(GO:0032024)
0.2	1.7	GO:2000035	regulation of stem cell division(GO:2000035)
0.2	0.8	GO:0051967	negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.2	4.7	GO:0021680	cerebellar Purkinje cell layer development(GO:0021680)
0.2	2.5	GO:0072661	protein targeting to plasma membrane(GO:0072661)
0.2	7.9	GO:0006739	NADP metabolic process(GO:0006739)
0.2	3.2	GO:0036159	inner dynein arm assembly(GO:0036159)
0.2	0.4	GO:0060825	fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
0.2	2.3	GO:0033005	positive regulation of mast cell activation(GO:0033005)
0.2	3.4	GO:0009880	embryonic pattern specification(GO:0009880)
0.2	10.5	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.2	1.2	GO:0006703	estrogen biosynthetic process(GO:0006703)
0.2	2.7	GO:0051893	regulation of focal adhesion assembly(GO:0051893) regulation of cell-substrate junction assembly(GO:0090109)
0.2	0.8	GO:0019243	methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.2	0.9	GO:2000169	negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083) regulation of peptidyl-cysteine S-nitrosylation(GO:2000169)
0.1	7.1	GO:0001657	ureteric bud development(GO:0001657) mesonephric epithelium development(GO:0072163) mesonephric tubule development(GO:0072164)
0.1	2.4	GO:0030514	negative regulation of BMP signaling pathway(GO:0030514)
0.1	19.8	GO:0006520	cellular amino acid metabolic process(GO:0006520)
0.1	1.7	GO:0035019	somatic stem cell population maintenance(GO:0035019)
0.1	1.4	GO:0007520	myoblast fusion(GO:0007520)
0.1	2.0	GO:0045840	positive regulation of mitotic nuclear division(GO:0045840)
0.1	0.3	GO:0055017	cardiac muscle tissue growth(GO:0055017)
0.1	0.8	GO:0035563	positive regulation of chromatin binding(GO:0035563)
0.1	1.5	GO:0031167	rRNA methylation(GO:0031167)
0.1	1.6	GO:0051931	regulation of sensory perception of pain(GO:0051930) regulation of sensory perception(GO:0051931)
0.1	2.0	GO:0046470	phosphatidylcholine metabolic process(GO:0046470)
0.1	2.4	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1	3.8	GO:0006986	response to unfolded protein(GO:0006986)
0.1	1.3	GO:0019433	triglyceride catabolic process(GO:0019433)
0.1	4.0	GO:0000045	autophagosome assembly(GO:0000045)
0.1	1.0	GO:0019236	response to pheromone(GO:0019236)
0.1	1.2	GO:0008593	regulation of Notch signaling pathway(GO:0008593)
0.1	1.1	GO:0045103	intermediate filament-based process(GO:0045103)
0.1	3.1	GO:0071427	mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0	1.4	GO:0000028	ribosomal small subunit assembly(GO:0000028)
0.0	0.7	GO:0060046	regulation of acrosome reaction(GO:0060046)
0.0	0.7	GO:0000729	DNA double-strand break processing(GO:0000729)
0.0	1.5	GO:0051290	protein heterotetramerization(GO:0051290)
0.0	0.1	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.0	50.3	GO:0007606	sensory perception of chemical stimulus(GO:0007606)
0.0	0.4	GO:0001919	regulation of receptor recycling(GO:0001919)
0.0	0.4	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0	0.1	GO:0045218	zonula adherens maintenance(GO:0045218)
0.0	0.2	GO:0006646	phosphatidylethanolamine biosynthetic process(GO:0006646)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
22.0	88.0	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
17.3	69.3	GO:0097513	myosin II filament(GO:0097513)
16.8	50.5	GO:0090498	extrinsic component of Golgi membrane(GO:0090498)
15.7	47.2	GO:0034667	integrin alpha3-beta1 complex(GO:0034667)
15.4	123.0	GO:0098642	collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
14.4	57.6	GO:1990761	growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
13.3	53.3	GO:0043259	laminin-10 complex(GO:0043259)
11.7	35.2	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
11.7	93.7	GO:0005964	phosphorylase kinase complex(GO:0005964)
11.2	44.7	GO:0099524	region of cytosol(GO:0099522) postsynaptic cytosol(GO:0099524)
10.6	63.5	GO:0042567	insulin-like growth factor ternary complex(GO:0042567)
10.2	40.6	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
9.6	115.1	GO:0005861	troponin complex(GO:0005861)
9.0	63.0	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
8.6	17.2	GO:0097444	spine apparatus(GO:0097444)
7.6	38.2	GO:0045098	type III intermediate filament(GO:0045098)
6.8	41.0	GO:0042584	chromaffin granule membrane(GO:0042584)
5.7	17.1	GO:0098855	HCN channel complex(GO:0098855)
5.6	27.9	GO:0044316	cone cell pedicle(GO:0044316)
5.5	27.3	GO:1903767	sweet taste receptor complex(GO:1903767) taste receptor complex(GO:1903768)
5.4	32.6	GO:0005865	striated muscle thin filament(GO:0005865)
5.2	98.8	GO:0016010	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
5.1	25.4	GO:0016327	apicolateral plasma membrane(GO:0016327)
5.1	15.2	GO:0005607	laminin-2 complex(GO:0005607)
5.0	25.1	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
4.9	38.9	GO:0065010	extracellular membrane-bounded organelle(GO:0065010)
4.8	267.2	GO:0031672	A band(GO:0031672)
4.4	13.2	GO:0005594	collagen type IX trimer(GO:0005594)
4.2	12.5	GO:0098982	glycine-gated chloride channel complex(GO:0016935) GABA-ergic synapse(GO:0098982)
4.1	20.5	GO:0071953	elastic fiber(GO:0071953)
4.0	16.2	GO:0005588	collagen type V trimer(GO:0005588)
4.0	15.9	GO:0072379	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
3.9	23.7	GO:0033269	internode region of axon(GO:0033269)
3.9	7.7	GO:0030314	junctional membrane complex(GO:0030314)
3.7	11.2	GO:1990032	parallel fiber(GO:1990032)
3.6	29.0	GO:0043203	axon hillock(GO:0043203)
3.4	20.2	GO:0008091	spectrin(GO:0008091)
3.3	63.3	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
3.1	12.6	GO:0071914	prominosome(GO:0071914)
3.1	33.7	GO:0032009	early phagosome(GO:0032009)
2.8	25.5	GO:0000813	ESCRT I complex(GO:0000813)
2.7	8.1	GO:0044302	dentate gyrus mossy fiber(GO:0044302)
2.6	15.9	GO:0044308	axonal spine(GO:0044308)
2.5	12.7	GO:0043293	apoptosome(GO:0043293)
2.4	43.8	GO:0043196	varicosity(GO:0043196)
2.4	31.0	GO:0031045	dense core granule(GO:0031045)
2.3	11.6	GO:0031315	extrinsic component of mitochondrial outer membrane(GO:0031315)
2.0	71.7	GO:0014704	intercalated disc(GO:0014704)
2.0	32.8	GO:0005751	mitochondrial respiratory chain complex IV(GO:0005751)
2.0	58.9	GO:0033176	proton-transporting V-type ATPase complex(GO:0033176)
2.0	41.5	GO:0033017	sarcoplasmic reticulum membrane(GO:0033017)
2.0	53.3	GO:0001533	cornified envelope(GO:0001533)
2.0	7.9	GO:0097025	MPP7-DLG1-LIN7 complex(GO:0097025)
1.9	60.4	GO:0097440	apical dendrite(GO:0097440)
1.9	5.7	GO:0031310	integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
1.8	190.5	GO:0031225	anchored component of membrane(GO:0031225)
1.8	31.9	GO:0034706	sodium channel complex(GO:0034706)
1.7	46.1	GO:0042629	mast cell granule(GO:0042629)
1.6	63.3	GO:0030315	T-tubule(GO:0030315)
1.6	40.2	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
1.6	3.2	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
1.5	16.7	GO:0099634	postsynaptic specialization membrane(GO:0099634)
1.5	31.7	GO:0031091	platelet alpha granule(GO:0031091)
1.5	9.0	GO:0030061	mitochondrial crista(GO:0030061)
1.5	44.6	GO:0008305	integrin complex(GO:0008305)
1.4	11.6	GO:0031313	extrinsic component of endosome membrane(GO:0031313)
1.4	20.2	GO:0043194	axon initial segment(GO:0043194)
1.4	4.3	GO:0097451	glial limiting end-foot(GO:0097451)
1.4	5.7	GO:0043564	Ku70:Ku80 complex(GO:0043564)
1.4	268.6	GO:0030016	myofibril(GO:0030016)
1.4	8.3	GO:1990909	Wnt signalosome(GO:1990909)
1.4	4.1	GO:0005958	DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
1.4	16.4	GO:0005796	Golgi lumen(GO:0005796)
1.3	21.1	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
1.3	5.2	GO:0018444	translation release factor complex(GO:0018444)
1.3	45.3	GO:0005771	multivesicular body(GO:0005771)
1.2	9.7	GO:0005583	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
1.2	3.6	GO:1990597	AIP1-IRE1 complex(GO:1990597)
1.2	18.9	GO:0030673	axolemma(GO:0030673)
1.1	8.0	GO:0000137	Golgi cis cisterna(GO:0000137)
1.1	4.5	GO:0030478	actin cap(GO:0030478)
1.1	17.0	GO:0005883	neurofilament(GO:0005883)
1.1	5.6	GO:0034751	aryl hydrocarbon receptor complex(GO:0034751)
1.1	22.4	GO:0005782	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
1.1	12.3	GO:0001527	microfibril(GO:0001527) fibril(GO:0043205)
1.1	31.0	GO:0060077	inhibitory synapse(GO:0060077)
1.1	6.6	GO:0032983	kainate selective glutamate receptor complex(GO:0032983)
1.1	7.6	GO:0045179	apical cortex(GO:0045179)
1.0	18.1	GO:0005614	interstitial matrix(GO:0005614)
1.0	7.0	GO:0061617	MICOS complex(GO:0061617)
1.0	18.8	GO:0031231	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
1.0	22.5	GO:1902711	GABA-A receptor complex(GO:1902711)
1.0	2.9	GO:0033165	interphotoreceptor matrix(GO:0033165)
0.9	9.4	GO:0044294	dendritic growth cone(GO:0044294)
0.9	10.3	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.9	42.8	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.9	15.4	GO:0016529	sarcoplasmic reticulum(GO:0016529)
0.9	11.7	GO:0032839	dendrite cytoplasm(GO:0032839)
0.9	102.6	GO:0030176	integral component of endoplasmic reticulum membrane(GO:0030176)
0.9	82.9	GO:0008076	voltage-gated potassium channel complex(GO:0008076)
0.9	33.4	GO:0045177	apical part of cell(GO:0045177)
0.8	3.2	GO:0060091	kinocilium(GO:0060091)
0.8	22.6	GO:0005921	gap junction(GO:0005921)
0.8	5.3	GO:0071986	Ragulator complex(GO:0071986)
0.8	6.1	GO:0045261	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.7	115.9	GO:0043204	perikaryon(GO:0043204)
0.7	15.6	GO:0005753	mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.7	9.6	GO:0017119	Golgi transport complex(GO:0017119)
0.7	27.1	GO:0042383	sarcolemma(GO:0042383)
0.7	7.3	GO:0034464	BBSome(GO:0034464)
0.7	10.7	GO:0045180	basal cortex(GO:0045180)
0.7	26.1	GO:0016459	myosin complex(GO:0016459)
0.7	82.0	GO:0044309	dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.7	21.9	GO:0032420	stereocilium(GO:0032420)
0.7	34.2	GO:0031901	early endosome membrane(GO:0031901)
0.7	36.6	GO:0031256	leading edge membrane(GO:0031256)
0.7	2.0	GO:0033270	paranode region of axon(GO:0033270)
0.6	192.7	GO:0098857	membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.6	4.4	GO:0090543	Flemming body(GO:0090543)
0.6	3.8	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
0.6	12.5	GO:0032281	AMPA glutamate receptor complex(GO:0032281)
0.6	3.4	GO:0030140	trans-Golgi network transport vesicle(GO:0030140)
0.5	5.4	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.5	6.9	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.5	1.6	GO:0070557	PCNA-p21 complex(GO:0070557)
0.5	2.6	GO:0070695	FHF complex(GO:0070695)
0.5	46.1	GO:0030427	site of polarized growth(GO:0030427)
0.5	21.2	GO:0030964	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.5	98.5	GO:0098794	postsynapse(GO:0098794)
0.5	69.7	GO:0043209	myelin sheath(GO:0043209)
0.5	23.5	GO:0005581	collagen trimer(GO:0005581)
0.5	8.1	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.5	14.5	GO:0005774	vacuolar membrane(GO:0005774)
0.5	6.6	GO:0030864	cortical actin cytoskeleton(GO:0030864)
0.5	11.0	GO:0031304	intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.5	33.5	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.5	63.8	GO:0016323	basolateral plasma membrane(GO:0016323)
0.5	27.0	GO:0005811	lipid particle(GO:0005811)
0.4	6.5	GO:0048786	presynaptic active zone(GO:0048786)
0.4	164.9	GO:0031012	extracellular matrix(GO:0031012)
0.4	12.9	GO:0008180	COP9 signalosome(GO:0008180)
0.4	37.9	GO:0005923	bicellular tight junction(GO:0005923)
0.4	15.3	GO:0097517	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.4	5.9	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.4	14.0	GO:0030660	Golgi-associated vesicle membrane(GO:0030660)
0.4	10.4	GO:0032592	integral component of mitochondrial membrane(GO:0032592)
0.3	76.0	GO:0043025	neuronal cell body(GO:0043025)
0.3	6.0	GO:0000145	exocyst(GO:0000145)
0.3	4.1	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.3	15.7	GO:0005758	mitochondrial intermembrane space(GO:0005758)
0.3	5.2	GO:0005686	U2 snRNP(GO:0005686)
0.2	5.2	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.2	3.6	GO:0034451	centriolar satellite(GO:0034451)
0.2	17.3	GO:0030027	lamellipodium(GO:0030027)
0.2	1.3	GO:0030863	cortical cytoskeleton(GO:0030863)
0.2	0.9	GO:0001651	dense fibrillar component(GO:0001651)
0.2	30.2	GO:0016324	apical plasma membrane(GO:0016324)
0.2	12.8	GO:0000315	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.2	10.2	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.2	1.6	GO:0016272	prefoldin complex(GO:0016272)
0.2	1.3	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.2	7.6	GO:0045171	intercellular bridge(GO:0045171)
0.2	0.7	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.2	6.6	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.2	239.5	GO:0005739	mitochondrion(GO:0005739)
0.2	30.3	GO:0030141	secretory granule(GO:0030141)
0.2	2.0	GO:0070971	endoplasmic reticulum exit site(GO:0070971)
0.2	1.7	GO:0030119	AP-type membrane coat adaptor complex(GO:0030119)
0.2	4.1	GO:0005801	cis-Golgi network(GO:0005801)
0.1	3.6	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.1	1.6	GO:0005791	rough endoplasmic reticulum(GO:0005791)
0.1	5.5	GO:0005770	late endosome(GO:0005770)
0.1	11.9	GO:0010008	endosome membrane(GO:0010008)
0.1	1.3	GO:0097542	ciliary tip(GO:0097542)
0.1	21.9	GO:0005912	adherens junction(GO:0005912)
0.1	6.3	GO:0000922	spindle pole(GO:0000922)
0.1	19.8	GO:0005874	microtubule(GO:0005874)
0.1	41.4	GO:0005794	Golgi apparatus(GO:0005794)
0.1	248.6	GO:0016021	integral component of membrane(GO:0016021)
0.1	1.1	GO:0000346	transcription export complex(GO:0000346)
0.1	21.7	GO:0005789	endoplasmic reticulum membrane(GO:0005789)
0.0	0.4	GO:0005871	kinesin complex(GO:0005871)
0.0	7.9	GO:0005783	endoplasmic reticulum(GO:0005783)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
22.0	88.0	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
18.9	226.4	GO:0019911	structural constituent of myelin sheath(GO:0019911)
16.1	48.2	GO:0016403	dimethylargininase activity(GO:0016403)
15.2	60.9	GO:0016842	amidine-lyase activity(GO:0016842)
13.7	27.5	GO:0030172	troponin C binding(GO:0030172)
11.7	93.7	GO:0004689	phosphorylase kinase activity(GO:0004689)
11.3	34.0	GO:0004566	beta-glucuronidase activity(GO:0004566)
11.2	33.5	GO:0071885	N-terminal protein N-methyltransferase activity(GO:0071885)
11.0	33.1	GO:0004657	proline dehydrogenase activity(GO:0004657)
10.6	31.7	GO:0031752	D5 dopamine receptor binding(GO:0031752)
10.1	81.1	GO:0071253	connexin binding(GO:0071253)
8.4	25.2	GO:0035939	microsatellite binding(GO:0035939)
8.1	24.4	GO:0033906	hyaluronoglucuronidase activity(GO:0033906)
7.5	37.5	GO:0070052	collagen V binding(GO:0070052)
7.4	51.7	GO:0031014	troponin T binding(GO:0031014)
7.3	65.5	GO:0031995	insulin-like growth factor II binding(GO:0031995)
7.2	28.8	GO:0015111	iodide transmembrane transporter activity(GO:0015111)
7.2	21.6	GO:0005171	hepatocyte growth factor receptor binding(GO:0005171)
6.9	20.6	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
6.8	27.3	GO:0003842	1-pyrroline-5-carboxylate dehydrogenase activity(GO:0003842)
6.8	20.4	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
6.7	53.7	GO:0008430	selenium binding(GO:0008430)
6.5	19.4	GO:0051425	PTB domain binding(GO:0051425)
5.9	23.7	GO:0008489	UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity(GO:0008489)
5.9	17.6	GO:0051538	3 iron, 4 sulfur cluster binding(GO:0051538)
5.5	253.5	GO:0008307	structural constituent of muscle(GO:0008307)
5.5	71.4	GO:0019215	intermediate filament binding(GO:0019215)
5.5	21.8	GO:0048101	calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
5.2	25.8	GO:0048495	Roundabout binding(GO:0048495)
5.1	66.4	GO:0004089	carbonate dehydratase activity(GO:0004089)
5.1	50.8	GO:0031432	titin binding(GO:0031432)
5.0	25.1	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
4.9	69.3	GO:0030898	actin-dependent ATPase activity(GO:0030898)
4.9	38.9	GO:0004035	alkaline phosphatase activity(GO:0004035)
4.8	24.0	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
4.8	19.2	GO:0097108	hedgehog family protein binding(GO:0097108)
4.8	14.4	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
4.6	55.5	GO:0009931	calcium-dependent protein serine/threonine kinase activity(GO:0009931)
4.6	87.8	GO:0005242	inward rectifier potassium channel activity(GO:0005242)
4.6	64.5	GO:0005523	tropomyosin binding(GO:0005523)
4.3	17.2	GO:0008532	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
4.3	17.1	GO:0016300	tRNA (uracil) methyltransferase activity(GO:0016300)
4.2	37.5	GO:0070061	fructose binding(GO:0070061)
4.2	12.5	GO:0022852	glycine-gated chloride ion channel activity(GO:0022852)
4.1	56.9	GO:0030550	acetylcholine receptor inhibitor activity(GO:0030550)
4.0	16.2	GO:0003839	gamma-glutamylcyclotransferase activity(GO:0003839)
4.0	19.8	GO:0004614	phosphoglucomutase activity(GO:0004614)
4.0	11.9	GO:0008948	oxaloacetate decarboxylase activity(GO:0008948) hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
3.7	18.7	GO:0030348	syntaxin-3 binding(GO:0030348)
3.7	33.0	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
3.6	18.0	GO:0004351	glutamate decarboxylase activity(GO:0004351)
3.6	21.6	GO:0003960	NADPH:quinone reductase activity(GO:0003960)
3.6	21.5	GO:0046920	alpha-(1->3)-fucosyltransferase activity(GO:0046920)
3.5	31.9	GO:0015280	ligand-gated sodium channel activity(GO:0015280)
3.5	21.1	GO:0005095	GTPase inhibitor activity(GO:0005095)
3.4	16.8	GO:0005111	type 1 fibroblast growth factor receptor binding(GO:0005105) type 2 fibroblast growth factor receptor binding(GO:0005111)
3.3	10.0	GO:0002060	purine nucleobase binding(GO:0002060)
3.2	6.5	GO:0038181	bile acid receptor activity(GO:0038181)
3.1	9.3	GO:0003845	11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
3.1	9.2	GO:0043812	phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
3.1	21.4	GO:0034711	inhibin binding(GO:0034711)
3.0	12.1	GO:0005333	norepinephrine transmembrane transporter activity(GO:0005333)
3.0	196.4	GO:0005201	extracellular matrix structural constituent(GO:0005201)
3.0	42.0	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
2.9	14.7	GO:0051575	5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
2.9	20.4	GO:0015526	hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
2.9	17.2	GO:0008294	calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
2.8	22.8	GO:0016421	CoA carboxylase activity(GO:0016421)
2.8	22.5	GO:0032184	SUMO polymer binding(GO:0032184)
2.8	5.6	GO:0017098	sulfonylurea receptor binding(GO:0017098)
2.8	8.4	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
2.8	144.3	GO:0035255	ionotropic glutamate receptor binding(GO:0035255)
2.7	35.1	GO:0030215	semaphorin receptor binding(GO:0030215)
2.6	7.8	GO:0031871	proteinase activated receptor binding(GO:0031871)
2.6	7.8	GO:0042978	ornithine decarboxylase activator activity(GO:0042978)
2.6	57.3	GO:0051428	peptide hormone receptor binding(GO:0051428)
2.6	25.8	GO:0003680	AT DNA binding(GO:0003680)
2.6	7.7	GO:0004724	magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
2.6	7.7	GO:0004500	dopamine beta-monooxygenase activity(GO:0004500)
2.6	15.4	GO:0090599	alpha-glucosidase activity(GO:0090599)
2.5	17.6	GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
2.5	17.4	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
2.5	7.4	GO:0004466	long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
2.4	16.7	GO:0004065	arylsulfatase activity(GO:0004065)
2.3	9.4	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
2.3	13.5	GO:0032051	clathrin light chain binding(GO:0032051)
2.2	20.2	GO:0086080	protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
2.2	22.4	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
2.2	11.0	GO:0050833	pyruvate transmembrane transporter activity(GO:0050833)
2.1	38.6	GO:0043274	phospholipase binding(GO:0043274)
2.1	8.6	GO:0051377	mannose-ethanolamine phosphotransferase activity(GO:0051377)
2.1	34.2	GO:0005159	insulin-like growth factor receptor binding(GO:0005159)
2.1	23.4	GO:0070700	BMP receptor binding(GO:0070700)
2.1	38.3	GO:0048156	tau protein binding(GO:0048156)
2.1	14.7	GO:0035033	histone deacetylase regulator activity(GO:0035033)
2.1	10.4	GO:0051185	coenzyme transporter activity(GO:0051185)
2.1	14.6	GO:0008484	sulfuric ester hydrolase activity(GO:0008484)
2.1	49.6	GO:0031489	myosin V binding(GO:0031489)
2.0	24.2	GO:0016500	protein-hormone receptor activity(GO:0016500)
2.0	21.5	GO:0004887	thyroid hormone receptor activity(GO:0004887)
1.9	209.1	GO:0005178	integrin binding(GO:0005178)
1.9	57.7	GO:0030552	cAMP binding(GO:0030552)
1.9	34.4	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
1.9	11.2	GO:0035662	Toll-like receptor 4 binding(GO:0035662)
1.8	7.1	GO:0045134	uridine-diphosphatase activity(GO:0045134)
1.8	45.7	GO:0004707	MAP kinase activity(GO:0004707)
1.7	45.2	GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
1.7	91.5	GO:0015459	potassium channel regulator activity(GO:0015459)
1.7	44.4	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
1.7	49.5	GO:0003785	actin monomer binding(GO:0003785)
1.7	19.9	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
1.7	8.3	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
1.7	28.1	GO:0042813	Wnt-activated receptor activity(GO:0042813)
1.6	25.8	GO:0046961	proton-transporting ATPase activity, rotational mechanism(GO:0046961)
1.6	8.0	GO:0061676	importin-alpha family protein binding(GO:0061676)
1.6	19.2	GO:0005243	gap junction channel activity(GO:0005243)
1.6	7.9	GO:0004716	receptor signaling protein tyrosine kinase activity(GO:0004716)
1.6	14.1	GO:0019992	diacylglycerol binding(GO:0019992)
1.6	32.9	GO:0001871	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
1.5	47.2	GO:0046875	ephrin receptor binding(GO:0046875)
1.5	15.2	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
1.5	9.1	GO:0017040	ceramidase activity(GO:0017040)
1.5	12.0	GO:0045499	chemorepellent activity(GO:0045499)
1.5	4.5	GO:0019807	aspartoacylase activity(GO:0019807)
1.5	23.7	GO:0034185	apolipoprotein binding(GO:0034185)
1.5	19.1	GO:0048406	nerve growth factor binding(GO:0048406)
1.5	29.2	GO:0070742	C2H2 zinc finger domain binding(GO:0070742)
1.5	93.1	GO:0032947	protein complex scaffold(GO:0032947)
1.5	10.2	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
1.4	44.7	GO:0051879	Hsp90 protein binding(GO:0051879)
1.4	21.5	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
1.4	24.1	GO:0030296	protein tyrosine kinase activator activity(GO:0030296)
1.4	5.6	GO:0016833	oxo-acid-lyase activity(GO:0016833)
1.4	11.0	GO:0035256	G-protein coupled glutamate receptor binding(GO:0035256)
1.4	4.1	GO:0004677	DNA-dependent protein kinase activity(GO:0004677)
1.4	29.9	GO:0001530	lipopolysaccharide binding(GO:0001530)
1.3	26.2	GO:0008373	sialyltransferase activity(GO:0008373)
1.3	30.1	GO:0071949	FAD binding(GO:0071949)
1.3	46.8	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624)
1.3	154.1	GO:0004222	metalloendopeptidase activity(GO:0004222)
1.3	6.3	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
1.2	13.6	GO:0045294	alpha-catenin binding(GO:0045294)
1.2	3.6	GO:0000253	3-keto sterol reductase activity(GO:0000253)
1.2	11.7	GO:0008046	axon guidance receptor activity(GO:0008046)
1.1	28.6	GO:0050431	transforming growth factor beta binding(GO:0050431)
1.1	27.4	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
1.1	32.8	GO:0015002	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
1.1	13.1	GO:0070008	serine-type exopeptidase activity(GO:0070008)
1.1	9.8	GO:0032036	myosin heavy chain binding(GO:0032036)
1.1	8.6	GO:0016413	O-acetyltransferase activity(GO:0016413)
1.1	68.5	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
1.1	22.3	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
1.0	22.0	GO:0043014	alpha-tubulin binding(GO:0043014)
1.0	20.7	GO:0016881	acid-amino acid ligase activity(GO:0016881)
1.0	82.7	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
1.0	3.0	GO:0009384	N-acylmannosamine kinase activity(GO:0009384)
1.0	43.6	GO:0048306	calcium-dependent protein binding(GO:0048306)
1.0	12.0	GO:0043024	ribosomal small subunit binding(GO:0043024)
1.0	6.9	GO:0038062	protein tyrosine kinase collagen receptor activity(GO:0038062)
1.0	14.8	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
1.0	7.7	GO:0030506	ankyrin binding(GO:0030506)
1.0	9.6	GO:0004331	fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.9	23.5	GO:0005328	neurotransmitter:sodium symporter activity(GO:0005328)
0.9	2.8	GO:0004478	methionine adenosyltransferase activity(GO:0004478)
0.9	6.4	GO:0035312	5'-3' exodeoxyribonuclease activity(GO:0035312)
0.9	12.6	GO:0033038	bitter taste receptor activity(GO:0033038)
0.9	19.6	GO:0043015	gamma-tubulin binding(GO:0043015)
0.9	7.1	GO:0008131	primary amine oxidase activity(GO:0008131)
0.9	28.5	GO:0017022	myosin binding(GO:0017022)
0.9	28.9	GO:0016831	carboxy-lyase activity(GO:0016831)
0.9	10.5	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
0.9	22.5	GO:0004890	GABA-A receptor activity(GO:0004890)
0.9	28.1	GO:0016879	ligase activity, forming carbon-nitrogen bonds(GO:0016879)
0.8	4.1	GO:0090555	phosphatidylethanolamine-translocating ATPase activity(GO:0090555)
0.8	5.0	GO:0034190	apolipoprotein receptor binding(GO:0034190)
0.8	3.3	GO:0071535	RING-like zinc finger domain binding(GO:0071535)
0.8	21.2	GO:0008137	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.8	11.6	GO:0035497	cAMP response element binding(GO:0035497)
0.8	3.0	GO:0001010	transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.7	5.2	GO:0045504	dynein heavy chain binding(GO:0045504)
0.7	11.2	GO:0019206	nucleoside kinase activity(GO:0019206)
0.7	9.6	GO:0017147	Wnt-protein binding(GO:0017147)
0.7	4.4	GO:0048030	disaccharide binding(GO:0048030)
0.7	14.6	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.7	7.2	GO:0035613	RNA stem-loop binding(GO:0035613)
0.7	7.9	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.7	13.5	GO:0099604	calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.7	9.2	GO:0051378	serotonin binding(GO:0051378)
0.7	13.4	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
0.7	3.4	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.6	5.8	GO:0015386	potassium:proton antiporter activity(GO:0015386)
0.6	18.6	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.6	11.5	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.6	59.6	GO:0030165	PDZ domain binding(GO:0030165)
0.6	8.2	GO:0003796	lysozyme activity(GO:0003796)
0.6	12.0	GO:0071837	HMG box domain binding(GO:0071837)
0.6	23.0	GO:0030971	receptor tyrosine kinase binding(GO:0030971)
0.6	9.3	GO:0042056	chemoattractant activity(GO:0042056)
0.6	1.7	GO:0017034	Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.5	9.9	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
0.5	12.4	GO:0004190	aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.5	14.5	GO:0071855	neuropeptide receptor binding(GO:0071855)
0.5	3.2	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.5	4.2	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.5	11.5	GO:0048365	Rac GTPase binding(GO:0048365)
0.5	10.9	GO:0005112	Notch binding(GO:0005112)
0.5	1.6	GO:0019912	cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.5	3.1	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.5	3.5	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.5	10.4	GO:0070006	metalloaminopeptidase activity(GO:0070006)
0.5	1.5	GO:0000179	rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.5	4.9	GO:0019841	retinol binding(GO:0019841)
0.5	6.3	GO:0017160	Ral GTPase binding(GO:0017160)
0.5	1.4	GO:0071553	uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.5	6.7	GO:0031005	filamin binding(GO:0031005)
0.5	3.3	GO:0005384	manganese ion transmembrane transporter activity(GO:0005384)
0.5	1.4	GO:0050252	retinol O-fatty-acyltransferase activity(GO:0050252)
0.5	22.3	GO:0031072	heat shock protein binding(GO:0031072)
0.5	11.7	GO:0030332	cyclin binding(GO:0030332)
0.4	43.6	GO:0016503	pheromone receptor activity(GO:0016503)
0.4	21.8	GO:0008138	protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.4	5.2	GO:0003747	translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.4	13.3	GO:0019707	protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.4	12.9	GO:0051059	NF-kappaB binding(GO:0051059)
0.4	4.3	GO:0098505	G-rich strand telomeric DNA binding(GO:0098505)
0.4	13.2	GO:0015485	cholesterol binding(GO:0015485)
0.4	18.6	GO:0045182	translation regulator activity(GO:0045182)
0.4	2.5	GO:0035254	glutamate receptor binding(GO:0035254)
0.4	12.6	GO:0042805	actinin binding(GO:0042805)
0.4	6.3	GO:0004559	alpha-mannosidase activity(GO:0004559)
0.4	49.5	GO:0008201	heparin binding(GO:0008201)
0.4	32.7	GO:0051087	chaperone binding(GO:0051087)
0.4	4.8	GO:0051787	misfolded protein binding(GO:0051787)
0.4	1.2	GO:0005499	vitamin D binding(GO:0005499)
0.4	1.2	GO:0047025	3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
0.4	1.6	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)
0.4	4.7	GO:0008301	DNA binding, bending(GO:0008301)
0.4	29.3	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.4	6.2	GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769)
0.4	6.1	GO:0005337	nucleoside transmembrane transporter activity(GO:0005337)
0.3	17.4	GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.3	6.2	GO:0004383	guanylate cyclase activity(GO:0004383)
0.3	10.2	GO:0005355	glucose transmembrane transporter activity(GO:0005355)
0.3	8.1	GO:0005245	voltage-gated calcium channel activity(GO:0005245)
0.3	16.7	GO:0043621	protein self-association(GO:0043621)
0.3	1.0	GO:0102345	3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.3	1.9	GO:0004308	exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.3	2.9	GO:0015232	heme transporter activity(GO:0015232)
0.3	5.9	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.3	7.3	GO:0001103	RNA polymerase II repressing transcription factor binding(GO:0001103)
0.2	20.3	GO:0001085	RNA polymerase II transcription factor binding(GO:0001085)
0.2	22.8	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity(GO:0036459)
0.2	20.2	GO:0043130	ubiquitin binding(GO:0043130)
0.2	9.2	GO:0030145	manganese ion binding(GO:0030145)
0.2	0.9	GO:0042134	rRNA primary transcript binding(GO:0042134)
0.2	5.9	GO:0009055	electron carrier activity(GO:0009055)
0.2	5.7	GO:0070566	adenylyltransferase activity(GO:0070566)
0.2	3.2	GO:0004549	tRNA-specific ribonuclease activity(GO:0004549)
0.2	6.0	GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.2	15.5	GO:0035257	nuclear hormone receptor binding(GO:0035257)
0.2	4.7	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.2	12.7	GO:0008146	sulfotransferase activity(GO:0008146)
0.2	2.3	GO:0031683	G-protein beta/gamma-subunit complex binding(GO:0031683)
0.2	21.3	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.2	34.6	GO:0005543	phospholipid binding(GO:0005543)
0.2	0.8	GO:0004416	hydroxyacylglutathione hydrolase activity(GO:0004416)
0.2	2.1	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.1	5.5	GO:0004879	RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.1	1.2	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)
0.1	13.2	GO:0008080	N-acetyltransferase activity(GO:0008080)
0.1	2.1	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.1	44.5	GO:0004674	protein serine/threonine kinase activity(GO:0004674)
0.1	0.7	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.1	24.9	GO:0003779	actin binding(GO:0003779)
0.1	1.9	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1	4.6	GO:0016875	aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.1	9.1	GO:0005179	hormone activity(GO:0005179)
0.1	11.4	GO:0008168	methyltransferase activity(GO:0008168)
0.1	2.0	GO:0004714	transmembrane receptor protein tyrosine kinase activity(GO:0004714) transmembrane receptor protein kinase activity(GO:0019199)
0.1	0.8	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.0	0.1	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.0	0.2	GO:0042577	lipid phosphatase activity(GO:0042577)
0.0	17.3	GO:0004984	olfactory receptor activity(GO:0004984)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
4.0	67.9	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
3.5	159.3	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
3.4	92.4	PID INTEGRIN CS PATHWAY	Integrin family cell surface interactions
3.2	118.6	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
2.5	65.7	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
2.3	39.7	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
2.3	103.1	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
2.3	9.1	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
2.2	37.2	PID S1P S1P2 PATHWAY	S1P2 pathway
2.2	87.1	PID NCADHERIN PATHWAY	N-cadherin signaling events
2.1	10.5	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
2.0	22.0	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
2.0	306.6	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
1.7	53.4	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
1.5	94.3	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
1.5	81.9	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
1.5	10.8	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
1.5	56.7	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
1.5	42.2	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
1.4	63.5	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
1.3	17.5	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
1.1	53.1	PID BMP PATHWAY	BMP receptor signaling
1.1	27.8	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions
1.0	17.2	PID LPA4 PATHWAY	LPA4-mediated signaling events
1.0	11.2	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
1.0	49.3	PID AP1 PATHWAY	AP-1 transcription factor network
1.0	26.2	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.9	215.6	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.9	57.0	PID NOTCH PATHWAY	Notch signaling pathway
0.9	10.7	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.7	27.1	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.7	13.2	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.7	15.9	PID LYSOPHOSPHOLIPID PATHWAY	LPA receptor mediated events
0.7	21.8	PID FGF PATHWAY	FGF signaling pathway
0.7	117.3	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.7	19.4	PID ARF6 PATHWAY	Arf6 signaling events
0.6	8.1	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.6	30.0	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.6	13.7	PID RAS PATHWAY	Regulation of Ras family activation
0.5	9.1	PID ARF 3PATHWAY	Arf1 pathway
0.5	21.6	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.5	5.7	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.4	20.2	PID PLK1 PATHWAY	PLK1 signaling events
0.4	4.5	PID EPHB FWD PATHWAY	EPHB forward signaling
0.4	4.9	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
0.4	3.9	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.3	11.2	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.2	11.7	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.2	5.8	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.2	6.3	PID FOXO PATHWAY	FoxO family signaling
0.2	4.5	PID CONE PATHWAY	Visual signal transduction: Cones
0.1	5.3	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.1	7.9	PID CMYB PATHWAY	C-MYB transcription factor network
0.1	2.9	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.1	3.4	PID P75 NTR PATHWAY	p75(NTR)-mediated signaling
0.1	1.3	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.1	3.0	WNT SIGNALING	Genes related to Wnt-mediated signal transduction
0.1	5.8	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
0.1	0.9	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0	1.9	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.0	1.3	PID LKB1 PATHWAY	LKB1 signaling events
0.0	0.2	PID HNF3A PATHWAY	FOXA1 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
8.8	341.5	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
5.1	101.9	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
5.0	213.0	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
4.8	177.6	REACTOME INWARDLY RECTIFYING K CHANNELS	Genes involved in Inwardly rectifying K+ channels
4.7	99.7	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
4.3	59.7	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII	Genes involved in CREB phosphorylation through the activation of CaMKII
4.0	93.0	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
3.8	134.3	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
3.1	53.2	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
3.1	40.1	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
2.9	26.4	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
2.9	41.0	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
2.6	47.0	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
2.6	31.0	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
2.4	21.7	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
2.3	30.5	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
2.3	37.0	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
2.2	65.0	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
2.2	24.4	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
2.2	19.7	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
2.2	173.8	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
2.1	57.5	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
2.1	19.2	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
2.1	8.4	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
2.0	62.3	REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE	Genes involved in Nitric oxide stimulates guanylate cyclase
2.0	50.8	REACTOME SHC MEDIATED CASCADE	Genes involved in SHC-mediated cascade
1.8	16.6	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
1.7	35.6	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
1.7	16.8	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
1.7	16.7	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
1.6	18.0	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
1.6	26.0	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
1.6	18.8	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
1.5	33.7	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
1.5	25.8	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
1.5	16.4	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
1.5	19.4	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
1.4	25.9	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
1.4	27.3	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
1.4	49.9	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
1.4	24.2	REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS	Genes involved in Post NMDA receptor activation events
1.3	21.2	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
1.3	33.0	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
1.3	23.7	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
1.3	20.9	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
1.3	10.3	REACTOME ARMS MEDIATED ACTIVATION	Genes involved in ARMS-mediated activation
1.2	10.9	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
1.2	14.1	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
1.1	7.9	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
1.0	17.6	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
1.0	9.0	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
1.0	8.9	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.9	51.3	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.9	13.0	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.9	33.4	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.9	19.4	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.9	121.3	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.9	15.4	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.9	94.7	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.9	7.1	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.9	7.0	REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING	Genes involved in Activation of Kainate Receptors upon glutamate binding
0.8	6.7	REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE	Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.8	13.9	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.8	63.6	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.8	30.2	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.8	40.5	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.8	14.7	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.8	7.6	REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS	Genes involved in Regulation of Water Balance by Renal Aquaporins
0.7	27.1	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.7	24.0	REACTOME SIGNALING BY FGFR	Genes involved in Signaling by FGFR
0.7	9.2	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.7	15.1	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.7	9.2	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.6	12.1	REACTOME PLC BETA MEDIATED EVENTS	Genes involved in PLC beta mediated events
0.6	26.8	REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL	Genes involved in Cell surface interactions at the vascular wall
0.6	7.7	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.5	45.3	REACTOME G ALPHA S SIGNALLING EVENTS	Genes involved in G alpha (s) signalling events
0.5	6.4	REACTOME SIGNALING BY ERBB2	Genes involved in Signaling by ERBB2
0.5	33.0	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.5	10.6	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.5	11.4	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.5	2.3	REACTOME ADP SIGNALLING THROUGH P2RY1	Genes involved in ADP signalling through P2Y purinoceptor 1
0.4	7.2	REACTOME AMINE LIGAND BINDING RECEPTORS	Genes involved in Amine ligand-binding receptors
0.4	12.5	REACTOME LIGAND GATED ION CHANNEL TRANSPORT	Genes involved in Ligand-gated ion channel transport
0.4	22.1	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.4	7.4	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.4	19.8	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.4	8.0	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.4	14.9	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.4	6.1	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.4	5.1	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.4	9.1	REACTOME SPHINGOLIPID METABOLISM	Genes involved in Sphingolipid metabolism
0.3	21.2	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.3	2.5	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.3	5.2	REACTOME GAP JUNCTION TRAFFICKING	Genes involved in Gap junction trafficking
0.3	3.3	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.2	7.1	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.2	11.6	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.2	4.4	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.2	3.4	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.2	5.5	REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters
0.2	11.3	REACTOME POTASSIUM CHANNELS	Genes involved in Potassium Channels
0.1	4.1	REACTOME DOUBLE STRAND BREAK REPAIR	Genes involved in Double-Strand Break Repair
0.1	7.8	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.1	3.0	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1	0.7	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.1	0.5	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.1	9.1	REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES	Genes involved in Metabolism of amino acids and derivatives
0.1	1.6	REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC	Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.1	1.5	REACTOME EXTRACELLULAR MATRIX ORGANIZATION	Genes involved in Extracellular matrix organization
0.0	2.4	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides

Results for Id4

Z-value: 2.23

Motif logo

Transcription factors associated with Id4

Activity-expression correlation:

Activity profile of Id4 motif

Sorted Z-values of Id4 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of Id4

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: