ISMARA results: Hsf2

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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Hsf2

Z-value: 1.04

Motif logo

Transcription factors associated with Hsf2

Gene Symbol	Gene ID	Gene Info
Hsf2 NCBI RGD Ensembl	ENSRNOG00000000808	heat shock transcription factor 2

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Hsf2	rn6_v1_chr20_+_38935820_38935820	0.78	1.6e-65	Click!

Activity profile of Hsf2 motif

Sorted Z-values of Hsf2 motif

Top targets:

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr2_+_200793571 Show fit	31.98	ENSRNOT00000091444	Hao2 NCBI RGD Ensembl Show fit	hydroxyacid oxidase 2
chr14_-_6679878 Show fit	25.94	ENSRNOT00000075989 ENSRNOT00000067875	Spp1 NCBI RGD Ensembl Show fit	secreted phosphoprotein 1
chr1_+_219964429 Show fit	25.93	ENSRNOT00000088288	Sptbn2 NCBI RGD Ensembl Show fit	spectrin, beta, non-erythrocytic 2
chr10_+_99388130 Show fit	21.62	ENSRNOT00000006238	Kcnj16 NCBI RGD Ensembl Show fit	potassium voltage-gated channel subfamily J member 16
chr9_-_80166807 Show fit	20.09	ENSRNOT00000079493	Igfbp5 NCBI RGD Ensembl Show fit	insulin-like growth factor binding protein 5
chr18_+_69841053 Show fit	19.92	ENSRNOT00000071545 ENSRNOT00000030613 ENSRNOT00000075543	Mro NCBI RGD Ensembl Show fit	maestro
chr18_-_1946840 Show fit	19.07	ENSRNOT00000041878	Abhd3 NCBI RGD Ensembl Show fit	abhydrolase domain containing 3
chr14_-_64535170 Show fit	17.55	ENSRNOT00000082338	Gba3 NCBI RGD Ensembl Show fit	glucosidase, beta, acid 3
chr1_+_153861569 Show fit	16.70	ENSRNOT00000023329	Me3 NCBI RGD Ensembl Show fit	malic enzyme 3
chr10_-_13115294 Show fit	15.78	ENSRNOT00000005899	NEWGENE_6497122 NCBI RGD Ensembl Show fit	FLYWCH family member 2
chr6_-_23542928 Show fit	15.72	ENSRNOT00000083858	Spdya NCBI RGD Ensembl Show fit	speedy/RINGO cell cycle regulator family member A
chrX_+_20351486 Show fit	15.65	ENSRNOT00000093675 ENSRNOT00000047444	Wnk3 NCBI RGD Ensembl Show fit	WNK lysine deficient protein kinase 3
chr8_-_73122740 Show fit	14.78	ENSRNOT00000012026	Tln2 NCBI RGD Ensembl Show fit	talin 2
chr14_-_78902063 Show fit	14.06	ENSRNOT00000088469	Ppp2r2c NCBI RGD Ensembl Show fit	protein phosphatase 2, regulatory subunit B, gamma
chr18_-_37096132 Show fit	13.77	ENSRNOT00000041188	Ppp2r2b NCBI RGD Ensembl Show fit	protein phosphatase 2, regulatory subunit B, beta
chr9_+_8349033 Show fit	13.73	ENSRNOT00000073775	LOC100360856 NCBI RGD Ensembl Show fit	hypothetical protein LOC100360856
chrX_+_106487870 Show fit	13.65	ENSRNOT00000075521	Arxes2 NCBI RGD Ensembl Show fit	adipocyte-related X-chromosome expressed sequence 2
chr1_-_173764246 Show fit	13.53	ENSRNOT00000019690 ENSRNOT00000086944	Lmo1 NCBI RGD Ensembl Show fit	LIM domain only 1
chr6_+_64808238 Show fit	13.40	ENSRNOT00000093195	Nrcam NCBI RGD Ensembl Show fit	neuronal cell adhesion molecule
chr1_-_188713270 Show fit	13.38	ENSRNOT00000082192 ENSRNOT00000065892	Gprc5b NCBI RGD Ensembl Show fit	G protein-coupled receptor, class C, group 5, member B
chr1_+_238222521 Show fit	13.34	ENSRNOT00000024000	Aldh1a1 NCBI RGD Ensembl Show fit	aldehyde dehydrogenase 1 family, member A1
chr8_+_131965134 Show fit	13.14	ENSRNOT00000078308	Znf660 NCBI RGD Ensembl Show fit	zinc finger protein 660
chrX_-_82743753 Show fit	13.07	ENSRNOT00000003512	Rps6ka6 NCBI RGD Ensembl Show fit	ribosomal protein S6 kinase A6
chr1_+_32221636 Show fit	12.94	ENSRNOT00000022346 ENSRNOT00000089941	Slc6a18 NCBI RGD Ensembl Show fit	solute carrier family 6 member 18
chr1_+_201901342 Show fit	12.87	ENSRNOT00000036657	RGD1559891 NCBI RGD Ensembl Show fit	similar to synaptonemal complex protein 3
chr7_+_129595192 Show fit	12.86	ENSRNOT00000071151	Zdhhc25 NCBI RGD Ensembl Show fit	zinc finger, DHHC-type containing 25
chr19_+_41482728 Show fit	12.86	ENSRNOT00000022943	Calb2 NCBI RGD Ensembl Show fit	calbindin 2
chr8_-_63750531 Show fit	12.73	ENSRNOT00000009496	Neo1 NCBI RGD Ensembl Show fit	neogenin 1
chr6_+_48708368 Show fit	12.67	ENSRNOT00000005905	Myt1l NCBI RGD Ensembl Show fit	myelin transcription factor 1-like
chr20_-_9855443 Show fit	12.55	ENSRNOT00000090275 ENSRNOT00000066266	Tff3 NCBI RGD Ensembl Show fit	trefoil factor 3
chr10_-_47825252 Show fit	12.54	ENSRNOT00000087102	Epn2 NCBI RGD Ensembl Show fit	epsin 2
chr9_+_23503236 Show fit	12.48	ENSRNOT00000017996	Crisp2 NCBI RGD Ensembl Show fit	cysteine-rich secretory protein 2
chr9_-_27452902 Show fit	12.29	ENSRNOT00000018325	Gsta1 NCBI RGD Ensembl Show fit	glutathione S-transferase alpha 1
chr3_-_111994337 Show fit	11.93	ENSRNOT00000030502	Pla2g4e NCBI RGD Ensembl Show fit	phospholipase A2, group IVE
chr4_+_153874852 Show fit	11.74	ENSRNOT00000079744	Slc6a13 NCBI RGD Ensembl Show fit	solute carrier family 6 member 13
chr11_-_87240833 Show fit	11.66	ENSRNOT00000052200	Tssk1b NCBI RGD Ensembl Show fit	testis-specific serine kinase 1B
chr1_-_240601744 Show fit	11.58	ENSRNOT00000024093	Aldh1a7 NCBI RGD Ensembl Show fit	aldehyde dehydrogenase family 1, subfamily A7
chr8_-_73164620 Show fit	11.46	ENSRNOT00000031988	Tln2 NCBI RGD Ensembl Show fit	talin 2
chr1_+_41323194 Show fit	11.44	ENSRNOT00000026350	Esr1 NCBI RGD Ensembl Show fit	estrogen receptor 1
chr2_-_181874223 Show fit	11.37	ENSRNOT00000035846	Rbm46 NCBI RGD Ensembl Show fit	RNA binding motif protein 46
chr10_+_103395511 Show fit	11.28	ENSRNOT00000004256	Gprc5c NCBI RGD Ensembl Show fit	G protein-coupled receptor, class C, group 5, member C
chr9_-_80167033 Show fit	11.26	ENSRNOT00000023530	Igfbp5 NCBI RGD Ensembl Show fit	insulin-like growth factor binding protein 5
chr7_-_130827152 Show fit	11.24	ENSRNOT00000019406	Syt10 NCBI RGD Ensembl Show fit	synaptotagmin 10
chr3_-_51612397 Show fit	11.17	ENSRNOT00000081401	Scn3a NCBI RGD Ensembl Show fit	sodium voltage-gated channel alpha subunit 3
chr8_-_82339937 Show fit	11.00	ENSRNOT00000080797	Mapk6 NCBI RGD Ensembl Show fit	mitogen-activated protein kinase 6
chr11_+_82862695 Show fit	10.98	ENSRNOT00000071707 ENSRNOT00000073435	Clcn2 NCBI RGD Ensembl Show fit	chloride voltage-gated channel 2
chr1_-_53589844 Show fit	10.97	ENSRNOT00000073581	Unc93a NCBI RGD Ensembl Show fit	unc-93 homolog A (C. elegans)
chr7_+_23012070 Show fit	10.86	ENSRNOT00000042460	LOC300308 NCBI RGD Ensembl Show fit	similar to hypothetical protein 4930509O22
chr5_-_62187930 Show fit	10.84	ENSRNOT00000011787	Coro2a NCBI RGD Ensembl Show fit	coronin 2A
chrX_+_116399611 Show fit	10.80	ENSRNOT00000050854	Zcchc16 NCBI RGD Ensembl Show fit	zinc finger CCHC-type containing 16
chr2_-_200625434 Show fit	10.73	ENSRNOT00000079754	Hsd3b5 NCBI RGD Ensembl Show fit	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5
chr5_+_71742911 Show fit	10.69	ENSRNOT00000047225	Zfp462 NCBI RGD Ensembl Show fit	zinc finger protein 462
chr2_+_45182402 Show fit	10.66	ENSRNOT00000060673	RGD1561161 NCBI RGD Ensembl Show fit	similar to BC067074 protein
chrX_-_115175299 Show fit	10.64	ENSRNOT00000074322	Dcx NCBI RGD Ensembl Show fit	doublecortin
chr7_+_144647587 Show fit	10.62	ENSRNOT00000022398	Hoxc4 NCBI RGD Ensembl Show fit	homeo box C4
chr8_+_85355766 Show fit	10.53	ENSRNOT00000010583	Gcm1 NCBI RGD Ensembl Show fit	glial cells missing homolog 1
chr14_+_64686793 Show fit	10.50	ENSRNOT00000005894 ENSRNOT00000036646	Adgra3 NCBI RGD Ensembl Show fit	adhesion G protein-coupled receptor A3
chr1_+_166739532 Show fit	10.42	ENSRNOT00000079846 ENSRNOT00000026665	Clpb NCBI RGD Ensembl Show fit	ClpB homolog, mitochondrial AAA ATPase chaperonin
chr1_+_81373340 Show fit	10.34	ENSRNOT00000026814	Zfp428 NCBI RGD Ensembl Show fit	zinc finger protein 428
chrX_+_33884499 Show fit	10.32	ENSRNOT00000090041	Reps2 NCBI RGD Ensembl Show fit	RALBP1 associated Eps domain containing protein 2
chr2_-_235177275 Show fit	10.32	ENSRNOT00000093153	LOC103691699 NCBI RGD Ensembl Show fit	uncharacterized LOC103691699
chr10_-_107539658 Show fit	10.17	ENSRNOT00000089346	Rbfox3 NCBI RGD Ensembl Show fit	RNA binding protein, fox-1 homolog 3
chr11_+_83884048 Show fit	10.11	ENSRNOT00000002376	LOC108348101 NCBI RGD Ensembl Show fit	chloride channel protein 2
chr3_-_64554953 Show fit	10.07	ENSRNOT00000067452	LOC102553814 NCBI RGD Ensembl Show fit	serine/arginine repetitive matrix protein 1-like
chrX_+_111122552 Show fit	10.03	ENSRNOT00000083566 ENSRNOT00000085078 ENSRNOT00000090928	Cldn2 NCBI RGD Ensembl Show fit	claudin 2
chr11_+_67221359 Show fit	9.99	ENSRNOT00000086097	Casr NCBI RGD Ensembl Show fit	calcium-sensing receptor
chr9_+_4817854 Show fit	9.95	ENSRNOT00000040879	LOC100910526 NCBI RGD Ensembl Show fit	sulfotransferase 1C2-like
chr1_+_217039755 Show fit	9.92	ENSRNOT00000091603	LOC102552318 NCBI RGD Ensembl Show fit	actin-like
chr4_-_14490446 Show fit	9.91	ENSRNOT00000009132	Sema3c NCBI RGD Ensembl Show fit	semaphorin 3C
chr7_+_140383397 Show fit	9.88	ENSRNOT00000090760	Ccdc65 NCBI RGD Ensembl Show fit	coiled-coil domain containing 65
chr4_-_100465106 Show fit	9.86	ENSRNOT00000086725 ENSRNOT00000057989	Elmod3 NCBI RGD Ensembl Show fit	ELMO domain containing 3
chr4_-_128266082 Show fit	9.86	ENSRNOT00000039549	Nup50 NCBI RGD Ensembl Show fit	nucleoporin 50
chr9_-_92530938 Show fit	9.81	ENSRNOT00000064875	Slc16a14 NCBI RGD Ensembl Show fit	solute carrier family 16, member 14
chr2_-_195678848 Show fit	9.77	ENSRNOT00000028303 ENSRNOT00000075569	Oaz3 NCBI RGD Ensembl Show fit	ornithine decarboxylase antizyme 3
chr9_-_63637677 Show fit	9.76	ENSRNOT00000049259	Satb2 NCBI RGD Ensembl Show fit	SATB homeobox 2
chrX_+_106523278 Show fit	9.73	ENSRNOT00000070802	MGC109340 NCBI RGD Ensembl Show fit	similar to Microsomal signal peptidase 23 kDa subunit (SPase 22 kDa subunit) (SPC22/23)
chr5_+_133896141 Show fit	9.66	ENSRNOT00000011434	Pdzk1ip1 NCBI RGD Ensembl Show fit	PDZK1 interacting protein 1
chr2_+_237148941 Show fit	9.56	ENSRNOT00000015116	Dkk2 NCBI RGD Ensembl Show fit	dickkopf WNT signaling pathway inhibitor 2
chr9_-_63291350 Show fit	9.53	ENSRNOT00000058831	Hsfy2 NCBI RGD Ensembl Show fit	heat shock transcription factor, Y linked 2
chr10_-_40201992 Show fit	9.47	ENSRNOT00000075311	Lyrm7 NCBI RGD Ensembl Show fit	LYR motif containing 7
chr14_+_12218553 Show fit	9.46	ENSRNOT00000003237	Prkg2 NCBI RGD Ensembl Show fit	protein kinase, cGMP-dependent, type II
chr16_+_66380173 Show fit	9.44	ENSRNOT00000048862	LOC681180 NCBI RGD Ensembl Show fit	similar to Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg)
chr1_+_199682688 Show fit	9.42	ENSRNOT00000027265 ENSRNOT00000080872	Slc5a2 NCBI RGD Ensembl Show fit	solute carrier family 5 member 2
chr6_-_99273033 Show fit	9.36	ENSRNOT00000088808	Tex21 NCBI RGD Ensembl Show fit	testis expressed 21
chr16_-_15798974 Show fit	9.33	ENSRNOT00000046842 ENSRNOT00000065946	Nrg3 NCBI RGD Ensembl Show fit	neuregulin 3
chr1_+_61786900 Show fit	9.32	ENSRNOT00000090287	AABR07001905.1 NCBI RGD Ensembl Show fit
chr2_-_89310946 Show fit	9.30	ENSRNOT00000015195	Ralyl NCBI RGD Ensembl Show fit	RALY RNA binding protein-like
chr9_+_10172832 Show fit	9.23	ENSRNOT00000074555	Acsbg2 NCBI RGD Ensembl Show fit	acyl-CoA synthetase bubblegum family member 2
chr1_-_266428239 Show fit	9.13	ENSRNOT00000027160	Cyp17a1 NCBI RGD Ensembl Show fit	cytochrome P450, family 17, subfamily a, polypeptide 1
chr5_-_78324278 Show fit	9.08	ENSRNOT00000082642 ENSRNOT00000048904	Wdr31 NCBI RGD Ensembl Show fit	WD repeat domain 31
chr9_+_4107246 Show fit	9.07	ENSRNOT00000078212	AABR07066160.1 NCBI RGD Ensembl Show fit
chr11_+_45339366 Show fit	8.81	ENSRNOT00000002241	Tmem30c NCBI RGD Ensembl Show fit	transmembrane protein 30C
chr2_-_231648122 Show fit	8.78	ENSRNOT00000014962	Ank2 NCBI RGD Ensembl Show fit	ankyrin 2
chr5_-_57372239 Show fit	8.78	ENSRNOT00000012975	Aqp7 NCBI RGD Ensembl Show fit	aquaporin 7
chr19_-_42180981 Show fit	8.74	ENSRNOT00000019577	Pmfbp1 NCBI RGD Ensembl Show fit	polyamine modulated factor 1 binding protein 1
chr13_-_111765944 Show fit	8.72	ENSRNOT00000073041	Syt14 NCBI RGD Ensembl Show fit	synaptotagmin 14
chr6_+_31011687 Show fit	8.68	ENSRNOT00000071242	AABR07063459.1 NCBI RGD Ensembl Show fit
chr4_+_61850348 Show fit	8.66	ENSRNOT00000013423	Akr1b7 NCBI RGD Ensembl Show fit	aldo-keto reductase family 1, member B7
chr13_-_84452181 Show fit	8.64	ENSRNOT00000005060	Mael NCBI RGD Ensembl Show fit	maelstrom spermatogenic transposon silencer
chr14_-_17582823 Show fit	8.62	ENSRNOT00000087686	LOC100911949 NCBI RGD Ensembl Show fit	uncharacterized LOC100911949
chr1_-_174119815 Show fit	8.55	ENSRNOT00000019368	Trim66 NCBI RGD Ensembl Show fit	tripartite motif-containing 66
chr7_+_123531682 Show fit	8.48	ENSRNOT00000010606	Wbp2nl NCBI RGD Ensembl Show fit	WBP2 N-terminal like
chr11_-_82938357 Show fit	8.42	ENSRNOT00000035945	Map3k13 NCBI RGD Ensembl Show fit	mitogen-activated protein kinase kinase kinase 13
chr1_-_224533219 Show fit	8.35	ENSRNOT00000051289	Ust5r NCBI RGD Ensembl Show fit	integral membrane transport protein UST5r
chr9_-_65790347 Show fit	8.35	ENSRNOT00000028506	AABR07067812.1 NCBI RGD Ensembl Show fit
chr10_-_13107771 Show fit	8.33	ENSRNOT00000005879	Flywch1 NCBI RGD Ensembl Show fit	FLYWCH-type zinc finger 1
chr10_+_93305969 Show fit	8.31	ENSRNOT00000008019	Efcab3 NCBI RGD Ensembl Show fit	EF-hand calcium binding domain 3
chrX_-_63961527 Show fit	8.27	ENSRNOT00000071762	Gspt2 NCBI RGD Ensembl Show fit	G1 to S phase transition 2
chr3_+_122928964 Show fit	8.26	ENSRNOT00000074724	LOC100365450 NCBI RGD Ensembl Show fit	rCG26795-like
chr19_-_42180362 Show fit	8.22	ENSRNOT00000089515	Pmfbp1 NCBI RGD Ensembl Show fit	polyamine modulated factor 1 binding protein 1
chr10_+_91187593 Show fit	8.19	ENSRNOT00000004163	Acbd4 NCBI RGD Ensembl Show fit	acyl-CoA binding domain containing 4
chr3_+_138974871 Show fit	8.16	ENSRNOT00000012524	Scp2d1 NCBI RGD Ensembl Show fit	SCP2 sterol-binding domain containing 1
chr13_+_99335020 Show fit	8.11	ENSRNOT00000029787	AABR07021930.1 NCBI RGD Ensembl Show fit
chr10_-_15166457 Show fit	8.05	ENSRNOT00000026676	Metrn NCBI RGD Ensembl Show fit	meteorin, glial cell differentiation regulator
chr1_+_217173199 Show fit	8.03	ENSRNOT00000075078	Shank2 NCBI RGD Ensembl Show fit	SH3 and multiple ankyrin repeat domains 2
chr13_-_112099336 Show fit	8.03	ENSRNOT00000009158 ENSRNOT00000044161	Camk1g NCBI RGD Ensembl Show fit	calcium/calmodulin-dependent protein kinase IG
chrX_-_105622156 Show fit	7.97	ENSRNOT00000029511	Armcx2 NCBI RGD Ensembl Show fit	armadillo repeat containing, X-linked 2
chr7_-_83670356 Show fit	7.96	ENSRNOT00000005584	Sybu NCBI RGD Ensembl Show fit	syntabulin
chr4_-_181348038 Show fit	7.95	ENSRNOT00000082879	LOC690784 NCBI RGD Ensembl Show fit	hypothetical protein LOC690783
chr6_-_111267734 Show fit	7.90	ENSRNOT00000074037	Noxred1 NCBI RGD Ensembl Show fit	NADP-dependent oxidoreductase domain containing 1
chr7_+_144623555 Show fit	7.86	ENSRNOT00000022217	Hoxc6 NCBI RGD Ensembl Show fit	homeo box C6
chr1_+_82174451 Show fit	7.86	ENSRNOT00000027783	Tmem145 NCBI RGD Ensembl Show fit	transmembrane protein 145
chr13_-_91427575 Show fit	7.80	ENSRNOT00000012092	Apcs NCBI RGD Ensembl Show fit	amyloid P component, serum
chr1_-_89559960 Show fit	7.70	ENSRNOT00000092133	Scn1b NCBI RGD Ensembl Show fit	sodium voltage-gated channel beta subunit 1
chr1_+_72860218 Show fit	7.56	ENSRNOT00000024547	Syt5 NCBI RGD Ensembl Show fit	synaptotagmin 5
chr2_-_187668677 Show fit	7.54	ENSRNOT00000056898 ENSRNOT00000092563	Tsacc NCBI RGD Ensembl Show fit	TSSK6 activating co-chaperone
chr8_-_115274165 Show fit	7.37	ENSRNOT00000056386	LOC102550160 NCBI RGD Ensembl Show fit	IQ domain-containing protein F5-like
chr18_-_28444880 Show fit	7.24	ENSRNOT00000060696	Prob1 NCBI RGD Ensembl Show fit	proline rich basic protein 1
chrX_+_157353577 Show fit	7.19	ENSRNOT00000090596	Haus7 NCBI RGD Ensembl Show fit	HAUS augmin-like complex, subunit 7
chr1_+_219233750 Show fit	7.18	ENSRNOT00000024112	Acy3 NCBI RGD Ensembl Show fit	aminoacylase 3
chr15_-_46381967 Show fit	7.12	ENSRNOT00000014198	Neil2 NCBI RGD Ensembl Show fit	nei-like DNA glycosylase 2
chr10_-_93679974 Show fit	7.11	ENSRNOT00000009316	March10 NCBI RGD Ensembl Show fit	membrane associated ring-CH-type finger 10
chr4_+_57823411 Show fit	7.10	ENSRNOT00000030462 ENSRNOT00000088235	Ssmem1 NCBI RGD Ensembl Show fit	serine-rich single-pass membrane protein 1
chr8_-_117211170 Show fit	7.07	ENSRNOT00000071189	Ccdc36 NCBI RGD Ensembl Show fit	coiled-coil domain containing 36
chr4_+_157057601 Show fit	7.04	ENSRNOT00000040592	Zfp42l NCBI RGD Ensembl Show fit	Zinc finger protein 42-like
chr10_+_45307007 Show fit	7.03	ENSRNOT00000003885	Trim17 NCBI RGD Ensembl Show fit	tripartite motif-containing 17
chr4_-_176720012 Show fit	7.00	ENSRNOT00000017965	Ldhb NCBI RGD Ensembl Show fit	lactate dehydrogenase B
chr8_+_70603249 Show fit	6.98	ENSRNOT00000067016 ENSRNOT00000072486	Igdcc4 NCBI RGD Ensembl Show fit	immunoglobulin superfamily, DCC subclass, member 4
chr7_+_40316639 Show fit	6.96	ENSRNOT00000080150	LOC500827 NCBI RGD Ensembl Show fit	similar to hypothetical protein FLJ35821
chr5_+_60528997 Show fit	6.90	ENSRNOT00000051445	Grhpr NCBI RGD Ensembl Show fit	glyoxylate and hydroxypyruvate reductase
chr10_-_34333305 Show fit	6.87	ENSRNOT00000071365	Olr1384 NCBI RGD Ensembl Show fit	olfactory receptor gene Olr1384
chr7_+_123482255 Show fit	6.86	ENSRNOT00000064487	LOC688613 NCBI RGD Ensembl Show fit	hypothetical protein LOC688613
chr20_+_5619012 Show fit	6.85	ENSRNOT00000000577	Ggnbp1 NCBI RGD Ensembl Show fit	gametogenetin binding protein 1
chr18_-_37776453 Show fit	6.84	ENSRNOT00000087876	Dpysl3 NCBI RGD Ensembl Show fit	dihydropyrimidinase-like 3
chr15_-_26175645 Show fit	6.84	ENSRNOT00000020175	Slc35f4 NCBI RGD Ensembl Show fit	solute carrier family 35, member F4
chr8_-_30222036 Show fit	6.83	ENSRNOT00000035454	Ntm NCBI RGD Ensembl Show fit	neurotrimin
chr1_-_62191818 Show fit	6.81	ENSRNOT00000033187	AABR07001926.1 NCBI RGD Ensembl Show fit
chr7_-_136853154 Show fit	6.79	ENSRNOT00000087376	Nell2 NCBI RGD Ensembl Show fit	neural EGFL like 2
chr20_+_1749716 Show fit	6.74	ENSRNOT00000048856	Olr1735 NCBI RGD Ensembl Show fit	olfactory receptor 1735
chr1_-_193459396 Show fit	6.66	ENSRNOT00000020281	Zkscan2 NCBI RGD Ensembl Show fit	zinc finger with KRAB and SCAN domains 2
chr9_-_114152716 Show fit	6.66	ENSRNOT00000044153	AABR07068650.1 NCBI RGD Ensembl Show fit
chr1_+_82169620 Show fit	6.65	ENSRNOT00000088955 ENSRNOT00000068251	Prr19 NCBI RGD Ensembl Show fit	proline rich 19
chr19_-_34752695 Show fit	6.65	ENSRNOT00000052018	Nr3c2 NCBI RGD Ensembl Show fit	nuclear receptor subfamily 3, group C, member 2
chr8_-_62332115 Show fit	6.64	ENSRNOT00000025783	Mpi NCBI RGD Ensembl Show fit	mannose phosphate isomerase (mapped)
chr1_-_18511695 Show fit	6.61	ENSRNOT00000075402	AABR07000583.1 NCBI RGD Ensembl Show fit
chr20_+_1764794 Show fit	6.59	ENSRNOT00000075084	Olr1736 NCBI RGD Ensembl Show fit	olfactory receptor 1736
chr10_-_107539465 Show fit	6.53	ENSRNOT00000004524	Rbfox3 NCBI RGD Ensembl Show fit	RNA binding protein, fox-1 homolog 3
chr3_+_170475831 Show fit	6.53	ENSRNOT00000006949	Fam209a NCBI RGD Ensembl Show fit	family with sequence similarity 209, member A
chr15_-_57651041 Show fit	6.51	ENSRNOT00000072138	Spert NCBI RGD Ensembl Show fit	spermatid associated
chr13_-_80862963 Show fit	6.50	ENSRNOT00000004864	Fmo3 NCBI RGD Ensembl Show fit	flavin containing monooxygenase 3
chr1_-_170397191 Show fit	6.46	ENSRNOT00000090181	Apbb1 NCBI RGD Ensembl Show fit	amyloid beta precursor protein binding family B member 1
chr1_+_243477493 Show fit	6.40	ENSRNOT00000021779 ENSRNOT00000085356	Dmrt1 NCBI RGD Ensembl Show fit	doublesex and mab-3 related transcription factor 1
chr17_+_47397558 Show fit	6.39	ENSRNOT00000085923	Epdr1 NCBI RGD Ensembl Show fit	ependymin related 1
chr20_+_40769586 Show fit	6.37	ENSRNOT00000001079	Fabp7 NCBI RGD Ensembl Show fit	fatty acid binding protein 7
chr11_-_86920094 Show fit	6.36	ENSRNOT00000063878	Ccdc188 NCBI RGD Ensembl Show fit	coiled-coil domain containing 188
chr9_+_50526811 Show fit	6.35	ENSRNOT00000036990	RGD1305645 NCBI RGD Ensembl Show fit	similar to RIKEN cDNA 1500015O10
chr8_-_40883880 Show fit	6.34	ENSRNOT00000075593	LOC102550797 NCBI RGD Ensembl Show fit	disks large homolog 5-like
chr13_+_51218468 Show fit	6.33	ENSRNOT00000033636	LOC289035 NCBI RGD Ensembl Show fit	similar to UDP-N-acetylglucosamine:a-1,3-D-mannoside beta-1,4-N-acetylgluco
chr3_-_3541947 Show fit	6.32	ENSRNOT00000024786	Nacc2 NCBI RGD Ensembl Show fit	NACC family member 2
chr15_+_28894627 Show fit	6.31	ENSRNOT00000017795	Olr1643 NCBI RGD Ensembl Show fit	olfactory receptor 1643
chr10_-_98294522 Show fit	6.29	ENSRNOT00000005489	Abca8 NCBI RGD Ensembl Show fit	ATP binding cassette subfamily A member 8
chr5_-_150949931 Show fit	6.27	ENSRNOT00000067905	Smpdl3b NCBI RGD Ensembl Show fit	sphingomyelin phosphodiesterase, acid-like 3B
chr4_-_482645 Show fit	6.26	ENSRNOT00000062073 ENSRNOT00000071713	Cnpy1 NCBI RGD Ensembl Show fit	canopy FGF signaling regulator 1
chr17_-_10766253 Show fit	6.25	ENSRNOT00000000117	Cplx2 NCBI RGD Ensembl Show fit	complexin 2
chr13_+_49074644 Show fit	6.21	ENSRNOT00000000041	Klhdc8a NCBI RGD Ensembl Show fit	kelch domain containing 8A
chr10_+_103396155 Show fit	6.21	ENSRNOT00000086924	Gprc5c NCBI RGD Ensembl Show fit	G protein-coupled receptor, class C, group 5, member C
chr3_+_97723901 Show fit	6.06	ENSRNOT00000080416	Mpped2 NCBI RGD Ensembl Show fit	metallophosphoesterase domain containing 2
chr20_+_4188766 Show fit	6.02	ENSRNOT00000081438 ENSRNOT00000060378	Tesb NCBI RGD Ensembl Show fit	testis specific basic protein
chr5_-_32956159 Show fit	6.02	ENSRNOT00000078264	Cnbd1 NCBI RGD Ensembl Show fit	cyclic nucleotide binding domain containing 1
chr8_+_117836701 Show fit	6.01	ENSRNOT00000043345	Plxnb1 NCBI RGD Ensembl Show fit	plexin B1
chr10_-_8654892 Show fit	5.99	ENSRNOT00000066534	Rbfox1 NCBI RGD Ensembl Show fit	RNA binding protein, fox-1 homolog 1
chr2_-_32518643 Show fit	5.98	ENSRNOT00000061032	Mast4 NCBI RGD Ensembl Show fit	microtubule associated serine/threonine kinase family member 4
chr1_-_81596819 Show fit	5.97	ENSRNOT00000074350	RGD1564380 NCBI RGD Ensembl Show fit	similar to BC049730 protein
chr4_+_163293724 Show fit	5.94	ENSRNOT00000077356	Gabarapl1 NCBI RGD Ensembl Show fit	GABA type A receptor associated protein like 1
chr4_-_163095614 Show fit	5.94	ENSRNOT00000088759	RGD1564770 NCBI RGD Ensembl Show fit	similar to CD69 antigen (p60, early T-cell activation antigen)
chr16_+_49485256 Show fit	5.83	ENSRNOT00000059317	RGD1564308 NCBI RGD Ensembl Show fit	similar to LOC495042 protein
chr3_+_114176309 Show fit	5.80	ENSRNOT00000023350	Sord NCBI RGD Ensembl Show fit	sorbitol dehydrogenase
chrX_+_119390013 Show fit	5.79	ENSRNOT00000074269	Agtr2 NCBI RGD Ensembl Show fit	angiotensin II receptor, type 2
chr18_-_58423196 Show fit	5.79	ENSRNOT00000025556	Piezo2 NCBI RGD Ensembl Show fit	piezo-type mechanosensitive ion channel component 2
chr20_-_5037022 Show fit	5.78	ENSRNOT00000091022 ENSRNOT00000060762	Msh5 NCBI RGD Ensembl Show fit	mutS homolog 5
chr18_+_30562178 Show fit	5.74	ENSRNOT00000040998	LOC108348771 NCBI RGD Ensembl Show fit	protocadherin beta-16-like
chr19_+_6046665 Show fit	5.72	ENSRNOT00000084126	Cdh8 NCBI RGD Ensembl Show fit	cadherin 8
chr2_+_154921999 Show fit	5.69	ENSRNOT00000057620	LOC691044 NCBI RGD Ensembl Show fit	similar to GTPase activating protein testicular GAP1
chr20_+_4959294 Show fit	5.67	ENSRNOT00000074223	Hspa1l NCBI RGD Ensembl Show fit	heat shock protein family A (Hsp70) member 1 like
chr7_+_119647375 Show fit	5.66	ENSRNOT00000046563	Kctd17 NCBI RGD Ensembl Show fit	potassium channel tetramerization domain containing 17
chr16_-_81880502 Show fit	5.63	ENSRNOT00000079096	Mcf2l NCBI RGD Ensembl Show fit	MCF.2 cell line derived transforming sequence-like
chr4_-_113988246 Show fit	5.61	ENSRNOT00000013128	LOC103692166 NCBI RGD Ensembl Show fit	WD repeat-containing protein 54
chr7_-_107203897 Show fit	5.61	ENSRNOT00000086263	Lrrc6 NCBI RGD Ensembl Show fit	leucine rich repeat containing 6
chr8_-_25829569 Show fit	5.58	ENSRNOT00000071884	Dpy19l2 NCBI RGD Ensembl Show fit	dpy-19 like 2
chr4_-_40385349 Show fit	5.55	ENSRNOT00000039005	Gpr85 NCBI RGD Ensembl Show fit	G protein-coupled receptor 85

Network of associatons between targets according to the STRING database.

First level regulatory network of Hsf2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
10.7	32.0	GO:0018924	mandelate metabolic process(GO:0018924)
8.6	25.9	GO:0006710	androgen catabolic process(GO:0006710)
7.8	31.3	GO:1904204	regulation of skeletal muscle hypertrophy(GO:1904204)
6.3	25.4	GO:1903015	regulation of exo-alpha-sialidase activity(GO:1903015)
5.2	15.6	GO:2000682	positive regulation of rubidium ion transport(GO:2000682) positive regulation of rubidium ion transmembrane transporter activity(GO:2000688)
3.5	10.6	GO:1990792	response to glial cell derived neurotrophic factor(GO:1990790) cellular response to glial cell derived neurotrophic factor(GO:1990792)
3.4	13.5	GO:0046013	regulation of T cell homeostatic proliferation(GO:0046013)
3.3	9.8	GO:1902268	negative regulation of polyamine transmembrane transport(GO:1902268)
3.2	9.5	GO:2001226	negative regulation of chloride transport(GO:2001226)
3.0	9.1	GO:0010034	response to acetate(GO:0010034)
3.0	9.0	GO:1990091	sodium-dependent self proteolysis(GO:1990091)
2.9	11.4	GO:1990375	baculum development(GO:1990375)
2.5	7.6	GO:0018916	nitrobenzene metabolic process(GO:0018916)
2.5	9.9	GO:0003350	pulmonary myocardium development(GO:0003350)
2.4	12.0	GO:0060689	cell differentiation involved in salivary gland development(GO:0060689)
2.4	26.2	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
2.3	9.3	GO:0021842	directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
2.3	11.6	GO:0035106	operant conditioning(GO:0035106)
2.3	2.3	GO:0035262	gonad morphogenesis(GO:0035262)
2.3	2.3	GO:0044240	multicellular organism lipid catabolic process(GO:0044240)
2.2	6.7	GO:1902380	positive regulation of mRNA cleavage(GO:0031439) positive regulation of endoribonuclease activity(GO:1902380) positive regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904722)
2.2	13.3	GO:0002072	optic cup morphogenesis involved in camera-type eye development(GO:0002072)
2.2	6.6	GO:0031959	mineralocorticoid receptor signaling pathway(GO:0031959)
2.2	8.8	GO:0036309	protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
2.2	25.9	GO:0016081	synaptic vesicle docking(GO:0016081)
2.1	23.4	GO:0006465	signal peptide processing(GO:0006465)
2.1	10.5	GO:0060018	astrocyte fate commitment(GO:0060018)
2.1	8.3	GO:0002184	cytoplasmic translational termination(GO:0002184)
2.0	8.2	GO:0010615	positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
2.0	6.0	GO:1900220	semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
1.9	5.8	GO:0006059	hexitol metabolic process(GO:0006059)
1.9	5.8	GO:0035566	G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199) regulation of metanephros size(GO:0035566)
1.9	18.9	GO:0046684	response to pyrethroid(GO:0046684)
1.8	8.8	GO:0015793	glycerol transport(GO:0015793)
1.7	5.2	GO:0021629	muscle attachment(GO:0016203) olfactory nerve morphogenesis(GO:0021627) olfactory nerve structural organization(GO:0021629)
1.7	6.9	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
1.7	13.5	GO:0060631	regulation of meiosis I(GO:0060631)
1.6	27.8	GO:0070262	peptidyl-serine dephosphorylation(GO:0070262)
1.5	4.4	GO:0051935	amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
1.4	15.9	GO:0021902	commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
1.4	4.3	GO:0042726	flavin-containing compound metabolic process(GO:0042726)
1.4	5.6	GO:0018103	protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
1.4	4.1	GO:0098971	anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
1.3	13.4	GO:0098870	neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
1.3	6.6	GO:0009298	GDP-mannose biosynthetic process(GO:0009298)
1.3	4.0	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
1.3	5.2	GO:0072268	nephrogenic mesenchyme development(GO:0072076) pattern specification involved in metanephros development(GO:0072268)
1.3	3.9	GO:0015744	succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422)
1.2	14.9	GO:0006108	malate metabolic process(GO:0006108)
1.2	12.3	GO:0042178	xenobiotic catabolic process(GO:0042178)
1.2	3.5	GO:0019255	glucose 1-phosphate metabolic process(GO:0019255)
1.1	3.4	GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
1.1	10.0	GO:0060613	fat pad development(GO:0060613)
1.1	15.2	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
1.1	4.2	GO:0006004	fucose metabolic process(GO:0006004)
1.0	4.2	GO:0060157	urinary bladder development(GO:0060157)
1.0	5.2	GO:1900620	acetylcholine biosynthetic process(GO:0008292) acetate ester biosynthetic process(GO:1900620)
1.0	5.1	GO:2000821	regulation of grooming behavior(GO:2000821)
1.0	7.0	GO:2000653	regulation of genetic imprinting(GO:2000653)
1.0	13.1	GO:2000381	negative regulation of mesoderm development(GO:2000381)
1.0	4.0	GO:0090611	ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
1.0	4.9	GO:0061668	mitochondrial ribosome assembly(GO:0061668)
1.0	3.9	GO:1903243	negative regulation of cardiac muscle hypertrophy in response to stress(GO:1903243)
1.0	6.8	GO:0070314	G1 to G0 transition(GO:0070314)
0.9	2.8	GO:0006532	aspartate biosynthetic process(GO:0006532)
0.9	4.7	GO:0070120	ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.9	8.4	GO:0060287	epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.9	9.1	GO:0098703	calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.9	12.7	GO:0048681	negative regulation of axon regeneration(GO:0048681)
0.9	2.7	GO:0002426	immunoglobulin production in mucosal tissue(GO:0002426)
0.9	6.3	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.9	13.3	GO:0042448	progesterone metabolic process(GO:0042448)
0.9	1.8	GO:1903544	response to butyrate(GO:1903544)
0.9	5.2	GO:1903361	protein localization to basolateral plasma membrane(GO:1903361)
0.8	8.5	GO:0007343	egg activation(GO:0007343)
0.8	3.4	GO:0021586	pons maturation(GO:0021586)
0.8	2.5	GO:0090247	cell motility involved in somitogenic axis elongation(GO:0090247) regulation of cell motility involved in somitogenic axis elongation(GO:0090249)
0.8	4.1	GO:0014816	skeletal muscle satellite cell differentiation(GO:0014816)
0.8	7.4	GO:2000344	positive regulation of acrosome reaction(GO:2000344)
0.8	4.9	GO:0002678	positive regulation of chronic inflammatory response(GO:0002678)
0.8	2.4	GO:0097037	heme export(GO:0097037)
0.8	3.2	GO:0061107	seminal vesicle development(GO:0061107)
0.8	7.9	GO:0006561	proline biosynthetic process(GO:0006561)
0.8	3.2	GO:0090666	scaRNA localization to Cajal body(GO:0090666)
0.8	7.9	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.8	4.7	GO:0035166	post-embryonic hemopoiesis(GO:0035166)
0.8	3.1	GO:0001661	conditioned taste aversion(GO:0001661)
0.8	24.5	GO:0010107	potassium ion import(GO:0010107)
0.8	2.3	GO:0034499	late endosome to Golgi transport(GO:0034499)
0.7	6.7	GO:0046543	development of secondary female sexual characteristics(GO:0046543)
0.7	3.6	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.7	2.2	GO:0040032	post-embryonic body morphogenesis(GO:0040032)
0.7	2.7	GO:1904158	axonemal central apparatus assembly(GO:1904158)
0.7	3.9	GO:0008050	female courtship behavior(GO:0008050)
0.6	2.6	GO:1900377	negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.6	3.9	GO:0030718	germ-line stem cell population maintenance(GO:0030718)
0.6	12.3	GO:0021819	layer formation in cerebral cortex(GO:0021819)
0.6	7.7	GO:0048642	negative regulation of skeletal muscle tissue development(GO:0048642)
0.6	1.3	GO:0014873	response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
0.6	8.0	GO:0098880	maintenance of postsynaptic specialization structure(GO:0098880) maintenance of postsynaptic density structure(GO:0099562)
0.6	2.5	GO:1903413	cellular response to bile acid(GO:1903413)
0.6	3.1	GO:1905150	regulation of voltage-gated sodium channel activity(GO:1905150)
0.6	1.8	GO:0032053	ciliary basal body organization(GO:0032053)
0.6	6.1	GO:0014883	transition between fast and slow fiber(GO:0014883)
0.6	5.4	GO:0016024	CDP-diacylglycerol biosynthetic process(GO:0016024)
0.6	1.8	GO:0010625	positive regulation of Schwann cell proliferation(GO:0010625)
0.6	5.1	GO:0055089	fatty acid homeostasis(GO:0055089)
0.5	4.4	GO:0030321	transepithelial chloride transport(GO:0030321)
0.5	4.4	GO:0070102	interleukin-6-mediated signaling pathway(GO:0070102)
0.5	4.3	GO:0071318	cellular response to ATP(GO:0071318)
0.5	8.6	GO:0034587	piRNA metabolic process(GO:0034587)
0.5	4.2	GO:0032815	negative regulation of natural killer cell activation(GO:0032815)
0.5	6.2	GO:0031915	positive regulation of synaptic plasticity(GO:0031915)
0.5	2.1	GO:0014878	response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.5	2.6	GO:0061709	reticulophagy(GO:0061709)
0.5	27.5	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.5	1.5	GO:0034971	growth plate cartilage chondrocyte proliferation(GO:0003419) histone H3-R17 methylation(GO:0034971)
0.5	3.0	GO:0045329	carnitine biosynthetic process(GO:0045329)
0.5	11.4	GO:0001829	trophectodermal cell differentiation(GO:0001829)
0.5	6.4	GO:0060134	prepulse inhibition(GO:0060134)
0.5	4.4	GO:0016127	cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.5	2.0	GO:0046351	disaccharide biosynthetic process(GO:0046351)
0.5	16.6	GO:0009395	phospholipid catabolic process(GO:0009395)
0.5	2.4	GO:0071603	endothelial cell-cell adhesion(GO:0071603)
0.5	5.8	GO:0099612	protein localization to axon(GO:0099612)
0.5	1.4	GO:0046947	hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.5	5.2	GO:0015747	urate transport(GO:0015747)
0.5	2.8	GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.4	1.8	GO:1904640	response to methionine(GO:1904640)
0.4	22.7	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.4	4.2	GO:0032287	peripheral nervous system myelin maintenance(GO:0032287)
0.4	11.7	GO:0015812	gamma-aminobutyric acid transport(GO:0015812)
0.4	6.2	GO:0021681	cerebellar granular layer development(GO:0021681)
0.4	0.8	GO:0009826	unidimensional cell growth(GO:0009826)
0.4	2.8	GO:0000711	meiotic DNA repair synthesis(GO:0000711)
0.4	12.6	GO:0046470	phosphatidylcholine metabolic process(GO:0046470)
0.4	1.2	GO:0021817	nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration(GO:0021817) nuclear migration along microtubule(GO:0030473) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.4	3.0	GO:0006735	NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.4	4.8	GO:0046415	urate metabolic process(GO:0046415)
0.4	1.8	GO:0033383	geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384)
0.4	3.2	GO:0007000	nucleolus organization(GO:0007000)
0.3	23.5	GO:0090263	positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.3	1.7	GO:0036233	glycine import(GO:0036233)
0.3	1.0	GO:0061643	chemoattraction of axon(GO:0061642) chemorepulsion of axon(GO:0061643)
0.3	2.6	GO:0006703	estrogen biosynthetic process(GO:0006703)
0.3	2.6	GO:0090336	positive regulation of brown fat cell differentiation(GO:0090336)
0.3	1.3	GO:0021779	oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.3	9.4	GO:1904659	hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.3	8.4	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.3	4.3	GO:0001967	suckling behavior(GO:0001967)
0.3	4.3	GO:0031167	rRNA methylation(GO:0031167)
0.3	10.1	GO:1903959	regulation of anion transmembrane transport(GO:1903959)
0.3	2.6	GO:0060385	axonogenesis involved in innervation(GO:0060385)
0.3	10.5	GO:0006972	hyperosmotic response(GO:0006972)
0.3	0.8	GO:0048749	compound eye development(GO:0048749)
0.3	7.0	GO:0006089	lactate metabolic process(GO:0006089)
0.3	1.7	GO:0070459	prolactin secretion(GO:0070459)
0.3	5.5	GO:0071157	negative regulation of cell cycle arrest(GO:0071157)
0.3	2.4	GO:0033572	transferrin transport(GO:0033572)
0.3	3.1	GO:0033141	regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033139) positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.3	0.5	GO:0014827	intestine smooth muscle contraction(GO:0014827)
0.3	4.6	GO:0097062	dendritic spine maintenance(GO:0097062)
0.3	0.5	GO:0031536	positive regulation of exit from mitosis(GO:0031536)
0.3	2.3	GO:1990001	inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341) inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.2	1.0	GO:0016998	cell wall macromolecule catabolic process(GO:0016998)
0.2	2.0	GO:0046339	diacylglycerol metabolic process(GO:0046339)
0.2	1.0	GO:0051792	medium-chain fatty acid biosynthetic process(GO:0051792)
0.2	1.7	GO:0071787	endoplasmic reticulum tubular network assembly(GO:0071787)
0.2	5.1	GO:0006099	tricarboxylic acid cycle(GO:0006099)
0.2	4.7	GO:0019432	triglyceride biosynthetic process(GO:0019432)
0.2	5.7	GO:0045724	positive regulation of cilium assembly(GO:0045724)
0.2	7.1	GO:0035036	sperm-egg recognition(GO:0035036)
0.2	1.4	GO:0007042	lysosomal lumen acidification(GO:0007042)
0.2	3.3	GO:0051923	sulfation(GO:0051923)
0.2	3.1	GO:0010839	negative regulation of keratinocyte proliferation(GO:0010839)
0.2	0.7	GO:0098939	dendritic transport of mitochondrion(GO:0098939) anterograde dendritic transport of mitochondrion(GO:0098972)
0.2	11.0	GO:0060999	positive regulation of dendritic spine development(GO:0060999)
0.2	10.7	GO:0043392	negative regulation of DNA binding(GO:0043392)
0.2	7.6	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.2	1.1	GO:1900122	positive regulation of receptor binding(GO:1900122)
0.2	2.8	GO:0055015	ventricular cardiac muscle cell development(GO:0055015)
0.2	2.1	GO:0042866	pyruvate biosynthetic process(GO:0042866)
0.2	2.3	GO:0090043	regulation of tubulin deacetylation(GO:0090043)
0.2	0.6	GO:1900748	positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748) positive regulation of lymphangiogenesis(GO:1901492)
0.2	5.6	GO:0035025	positive regulation of Rho protein signal transduction(GO:0035025)
0.2	5.1	GO:0071526	semaphorin-plexin signaling pathway(GO:0071526)
0.2	5.1	GO:0072661	protein targeting to plasma membrane(GO:0072661)
0.2	5.0	GO:0006298	mismatch repair(GO:0006298)
0.2	6.9	GO:0000266	mitochondrial fission(GO:0000266)
0.2	0.7	GO:0021526	medial motor column neuron differentiation(GO:0021526)
0.2	7.2	GO:0050974	detection of mechanical stimulus involved in sensory perception(GO:0050974)
0.2	3.1	GO:0007130	synaptonemal complex assembly(GO:0007130)
0.2	0.7	GO:1900378	positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.2	3.1	GO:0043968	histone H2A acetylation(GO:0043968)
0.2	1.3	GO:0035989	tendon development(GO:0035989) integrin biosynthetic process(GO:0045112)
0.2	6.8	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
0.2	1.0	GO:1903054	negative regulation of extracellular matrix organization(GO:1903054)
0.2	1.0	GO:0038170	somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.2	2.2	GO:0043457	regulation of cellular respiration(GO:0043457)
0.2	1.1	GO:0015866	ADP transport(GO:0015866)
0.2	1.5	GO:0048280	vesicle fusion with Golgi apparatus(GO:0048280)
0.2	1.5	GO:1990834	response to odorant(GO:1990834)
0.2	7.2	GO:0007588	excretion(GO:0007588)
0.2	3.6	GO:0016242	negative regulation of macroautophagy(GO:0016242)
0.1	3.2	GO:0010667	negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.1	4.6	GO:0018345	protein palmitoylation(GO:0018345)
0.1	7.6	GO:0051865	protein autoubiquitination(GO:0051865)
0.1	3.2	GO:0060712	spongiotrophoblast layer development(GO:0060712)
0.1	4.2	GO:1900087	positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.1	0.8	GO:0046836	glycolipid transport(GO:0046836)
0.1	1.6	GO:0051044	positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1	3.2	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.1	6.1	GO:0045739	positive regulation of DNA repair(GO:0045739)
0.1	0.8	GO:0070966	nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.1	5.0	GO:0048678	response to axon injury(GO:0048678)
0.1	0.6	GO:1904424	regulation of GTP binding(GO:1904424)
0.1	1.7	GO:0090557	establishment of endothelial intestinal barrier(GO:0090557)
0.1	0.6	GO:1904781	positive regulation of protein localization to centrosome(GO:1904781)
0.1	5.3	GO:0070830	bicellular tight junction assembly(GO:0070830)
0.1	4.8	GO:0034605	cellular response to heat(GO:0034605)
0.1	1.1	GO:0018026	peptidyl-lysine monomethylation(GO:0018026)
0.1	2.8	GO:0036119	response to platelet-derived growth factor(GO:0036119) cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.1	0.5	GO:0009235	cobalamin metabolic process(GO:0009235)
0.1	15.2	GO:0007286	spermatid development(GO:0007286)
0.1	0.4	GO:0045741	positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.1	0.5	GO:0042940	D-amino acid transport(GO:0042940)
0.1	0.6	GO:0090073	positive regulation of protein homodimerization activity(GO:0090073)
0.1	4.3	GO:0050772	positive regulation of axonogenesis(GO:0050772)
0.1	3.4	GO:0006284	base-excision repair(GO:0006284)
0.1	0.5	GO:0003433	chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
0.1	5.2	GO:0000186	activation of MAPKK activity(GO:0000186)
0.1	3.1	GO:0048384	retinoic acid receptor signaling pathway(GO:0048384)
0.1	1.0	GO:0009226	nucleotide-sugar biosynthetic process(GO:0009226)
0.1	0.6	GO:1901727	positive regulation of histone deacetylase activity(GO:1901727)
0.1	2.9	GO:0030514	negative regulation of BMP signaling pathway(GO:0030514)
0.1	6.8	GO:0021549	cerebellum development(GO:0021549)
0.1	2.2	GO:0045668	negative regulation of osteoblast differentiation(GO:0045668)
0.1	10.4	GO:0021915	neural tube development(GO:0021915)
0.1	3.5	GO:0006418	tRNA aminoacylation for protein translation(GO:0006418)
0.1	2.6	GO:0017144	drug metabolic process(GO:0017144)
0.1	0.8	GO:0051382	kinetochore assembly(GO:0051382)
0.1	13.2	GO:0016358	dendrite development(GO:0016358)
0.1	1.4	GO:0051481	negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.1	3.2	GO:0042108	positive regulation of cytokine biosynthetic process(GO:0042108)
0.1	3.0	GO:0009409	response to cold(GO:0009409)
0.1	2.3	GO:0035418	protein localization to synapse(GO:0035418)
0.1	2.0	GO:0002446	neutrophil mediated immunity(GO:0002446)
0.1	0.6	GO:1901387	positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.1	3.1	GO:0022904	respiratory electron transport chain(GO:0022904)
0.1	0.6	GO:0007035	vacuolar acidification(GO:0007035)
0.1	2.1	GO:0032456	endocytic recycling(GO:0032456)
0.1	0.2	GO:0009597	detection of virus(GO:0009597)
0.1	4.6	GO:0048706	embryonic skeletal system development(GO:0048706)
0.1	2.1	GO:0009250	glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.1	5.1	GO:0006694	steroid biosynthetic process(GO:0006694)
0.1	2.2	GO:0046677	response to antibiotic(GO:0046677)
0.1	2.5	GO:0010906	regulation of glucose metabolic process(GO:0010906)
0.1	3.2	GO:0035383	acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0	1.1	GO:0048635	negative regulation of muscle organ development(GO:0048635)
0.0	0.0	GO:1904154	positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.0	0.4	GO:1903690	negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0	1.0	GO:0046856	phosphatidylinositol dephosphorylation(GO:0046856)
0.0	47.1	GO:0050911	detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0	3.0	GO:0007416	synapse assembly(GO:0007416)
0.0	2.3	GO:1901659	glycosyl compound biosynthetic process(GO:1901659)
0.0	0.9	GO:0043268	positive regulation of potassium ion transport(GO:0043268)
0.0	3.5	GO:0016579	protein deubiquitination(GO:0016579)
0.0	1.4	GO:0035914	skeletal muscle cell differentiation(GO:0035914)
0.0	0.7	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.0	1.0	GO:0015804	neutral amino acid transport(GO:0015804)
0.0	0.3	GO:0042407	cristae formation(GO:0042407)
0.0	1.8	GO:0018107	peptidyl-threonine phosphorylation(GO:0018107)
0.0	2.3	GO:1902600	hydrogen ion transmembrane transport(GO:1902600)
0.0	0.9	GO:0061077	chaperone-mediated protein folding(GO:0061077)
0.0	0.9	GO:0032543	mitochondrial translation(GO:0032543)
0.0	0.1	GO:0086100	endothelin receptor signaling pathway(GO:0086100)
0.0	0.7	GO:0006900	membrane budding(GO:0006900)
0.0	0.1	GO:0003105	negative regulation of glomerular filtration(GO:0003105)
0.0	0.3	GO:0036158	outer dynein arm assembly(GO:0036158)
0.0	0.3	GO:0006516	glycoprotein catabolic process(GO:0006516)
0.0	0.6	GO:0045103	intermediate filament-based process(GO:0045103)
0.0	0.7	GO:0016575	histone deacetylation(GO:0016575)
0.0	0.1	GO:0048227	plasma membrane to endosome transport(GO:0048227)
0.0	0.2	GO:0008631	intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631)
0.0	1.0	GO:0090174	organelle membrane fusion(GO:0090174)
0.0	0.6	GO:0006888	ER to Golgi vesicle-mediated transport(GO:0006888)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
5.2	31.3	GO:0042567	insulin-like growth factor ternary complex(GO:0042567)
3.9	23.4	GO:0005787	signal peptidase complex(GO:0005787)
2.7	13.4	GO:1990769	proximal neuron projection(GO:1990769)
2.6	25.9	GO:0008091	spectrin(GO:0008091)
2.1	8.3	GO:0018444	translation release factor complex(GO:0018444)
2.0	6.1	GO:0071148	TEAD-1-YAP complex(GO:0071148)
1.6	26.2	GO:0005916	fascia adherens(GO:0005916)
1.6	6.5	GO:1990761	growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
1.6	4.7	GO:0070110	ciliary neurotrophic factor receptor complex(GO:0070110)
1.4	4.3	GO:0032437	cuticular plate(GO:0032437)
1.4	8.6	GO:0071547	piP-body(GO:0071547)
1.3	5.2	GO:0097025	MPP7-DLG1-LIN7 complex(GO:0097025)
1.2	4.9	GO:0030485	smooth muscle contractile fiber(GO:0030485)
1.2	11.8	GO:0097550	transcriptional preinitiation complex(GO:0097550)
1.1	3.4	GO:0005859	muscle myosin complex(GO:0005859)
1.1	30.3	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
1.1	3.4	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
1.0	6.2	GO:0070033	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.9	18.9	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
0.9	17.0	GO:0001520	outer dense fiber(GO:0001520)
0.9	8.0	GO:0097433	dense body(GO:0097433)
0.8	11.0	GO:0032156	septin cytoskeleton(GO:0032156)
0.8	2.3	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
0.7	13.4	GO:0043194	axon initial segment(GO:0043194)
0.7	9.6	GO:0002199	zona pellucida receptor complex(GO:0002199)
0.7	12.5	GO:0030128	clathrin coat of endocytic vesicle(GO:0030128)
0.7	2.2	GO:0090498	extrinsic component of Golgi membrane(GO:0090498)
0.7	7.2	GO:0070652	HAUS complex(GO:0070652)
0.7	2.8	GO:0016222	procollagen-proline 4-dioxygenase complex(GO:0016222)
0.7	2.0	GO:0009328	phenylalanine-tRNA ligase complex(GO:0009328)
0.6	7.9	GO:0008385	IkappaB kinase complex(GO:0008385)
0.6	2.4	GO:0061474	phagolysosome membrane(GO:0061474)
0.6	2.3	GO:0043541	UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.6	4.0	GO:0090543	Flemming body(GO:0090543)
0.6	7.4	GO:0060091	kinocilium(GO:0060091)
0.5	2.7	GO:1990716	axonemal central apparatus(GO:1990716)
0.5	8.0	GO:0005883	neurofilament(GO:0005883)
0.5	3.2	GO:1990393	Cul7-RING ubiquitin ligase complex(GO:0031467) 3M complex(GO:1990393)
0.5	3.0	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.5	5.6	GO:0030008	TRAPP complex(GO:0030008)
0.5	11.6	GO:0005640	nuclear outer membrane(GO:0005640)
0.5	5.9	GO:0000801	central element(GO:0000801)
0.5	12.3	GO:0031430	M band(GO:0031430)
0.5	4.1	GO:1990075	periciliary membrane compartment(GO:1990075)
0.4	3.1	GO:0030061	mitochondrial crista(GO:0030061)
0.4	1.8	GO:0098574	cytoplasmic side of lysosomal membrane(GO:0098574)
0.4	9.8	GO:0016581	NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.4	2.0	GO:0000220	vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.4	5.7	GO:0043083	synaptic cleft(GO:0043083)
0.4	17.4	GO:0016235	aggresome(GO:0016235)
0.4	10.5	GO:0005921	gap junction(GO:0005921)
0.3	5.2	GO:0045334	clathrin-coated endocytic vesicle(GO:0045334)
0.3	44.1	GO:0005923	bicellular tight junction(GO:0005923)
0.3	0.6	GO:0000322	storage vacuole(GO:0000322)
0.3	21.8	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.3	1.2	GO:0034993	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.3	1.2	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.3	5.1	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.3	2.2	GO:0031314	extrinsic component of mitochondrial inner membrane(GO:0031314)
0.3	5.2	GO:0090665	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.3	2.7	GO:0030062	mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.3	3.2	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.3	37.9	GO:0031514	motile cilium(GO:0031514)
0.3	7.9	GO:0032281	AMPA glutamate receptor complex(GO:0032281)
0.3	14.8	GO:0034707	chloride channel complex(GO:0034707)
0.2	39.1	GO:0005777	peroxisome(GO:0005777) microbody(GO:0042579)
0.2	17.6	GO:0031526	brush border membrane(GO:0031526)
0.2	6.6	GO:0032839	dendrite cytoplasm(GO:0032839)
0.2	1.4	GO:0030314	junctional membrane complex(GO:0030314)
0.2	1.0	GO:0044300	cerebellar mossy fiber(GO:0044300)
0.2	9.6	GO:0000118	histone deacetylase complex(GO:0000118)
0.2	5.8	GO:0032809	neuronal cell body membrane(GO:0032809)
0.2	3.7	GO:0002080	acrosomal membrane(GO:0002080)
0.2	4.6	GO:0005763	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.2	7.6	GO:0030315	T-tubule(GO:0030315)
0.2	3.1	GO:1902562	NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.1	8.2	GO:0005762	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1	12.1	GO:0000794	condensed nuclear chromosome(GO:0000794)
0.1	3.6	GO:0030687	preribosome, large subunit precursor(GO:0030687)
0.1	7.3	GO:0017053	transcriptional repressor complex(GO:0017053)
0.1	5.6	GO:0005637	nuclear inner membrane(GO:0005637)
0.1	3.9	GO:0044295	axonal growth cone(GO:0044295)
0.1	18.2	GO:0043204	perikaryon(GO:0043204)
0.1	3.8	GO:0016529	sarcoplasmic reticulum(GO:0016529)
0.1	4.6	GO:0055038	recycling endosome membrane(GO:0055038)
0.1	14.1	GO:0016323	basolateral plasma membrane(GO:0016323)
0.1	16.0	GO:0045211	postsynaptic membrane(GO:0045211)
0.1	39.6	GO:0045177	apical part of cell(GO:0045177)
0.1	11.8	GO:0030658	transport vesicle membrane(GO:0030658)
0.1	6.3	GO:0005643	nuclear pore(GO:0005643)
0.1	0.8	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)
0.1	7.4	GO:0001669	acrosomal vesicle(GO:0001669)
0.1	2.6	GO:0031201	SNARE complex(GO:0031201)
0.1	1.4	GO:0005751	mitochondrial respiratory chain complex IV(GO:0005751)
0.1	4.3	GO:0042645	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1	2.3	GO:0042734	presynaptic membrane(GO:0042734)
0.1	11.7	GO:0005759	mitochondrial matrix(GO:0005759)
0.1	1.1	GO:0033391	chromatoid body(GO:0033391)
0.1	0.6	GO:0008290	F-actin capping protein complex(GO:0008290)
0.1	3.9	GO:0055037	recycling endosome(GO:0055037)
0.1	1.5	GO:0030867	rough endoplasmic reticulum membrane(GO:0030867)
0.1	5.5	GO:0030176	integral component of endoplasmic reticulum membrane(GO:0030176)
0.0	3.5	GO:0045202	synapse(GO:0045202)
0.0	1.3	GO:0005689	U12-type spliceosomal complex(GO:0005689)
0.0	0.6	GO:0030134	ER to Golgi transport vesicle(GO:0030134)
0.0	0.8	GO:0005614	interstitial matrix(GO:0005614)
0.0	0.3	GO:0061617	MICOS complex(GO:0061617)
0.0	1.1	GO:0005839	proteasome core complex(GO:0005839)
0.0	3.2	GO:0070382	exocytic vesicle(GO:0070382)
0.0	1.6	GO:0045171	intercellular bridge(GO:0045171)
0.0	0.8	GO:0035327	transcriptionally active chromatin(GO:0035327)
0.0	0.4	GO:0045180	basal cortex(GO:0045180)
0.0	2.5	GO:0008076	voltage-gated potassium channel complex(GO:0008076)
0.0	0.7	GO:0005790	smooth endoplasmic reticulum(GO:0005790)
0.0	2.2	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.0	46.1	GO:0005739	mitochondrion(GO:0005739)
0.0	0.9	GO:0005876	spindle microtubule(GO:0005876)
0.0	1.3	GO:0043209	myelin sheath(GO:0043209)
0.0	0.3	GO:0030914	SAGA complex(GO:0000124) STAGA complex(GO:0030914)
0.0	1.4	GO:0031461	cullin-RING ubiquitin ligase complex(GO:0031461)
0.0	4.4	GO:0005929	cilium(GO:0005929)
0.0	0.6	GO:0031594	neuromuscular junction(GO:0031594)
0.0	7.4	GO:0048471	perinuclear region of cytoplasm(GO:0048471)
0.0	1.9	GO:0030027	lamellipodium(GO:0030027)
0.0	1.7	GO:0005802	trans-Golgi network(GO:0005802)
0.0	1.8	GO:0005814	centriole(GO:0005814)
0.0	14.2	GO:0097458	neuron part(GO:0097458)
0.0	0.5	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
10.7	32.0	GO:0052854	very-long-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052852) long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity(GO:0052853) medium-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052854)
8.3	24.9	GO:0018479	benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
5.9	17.6	GO:0017042	glycosylceramidase activity(GO:0017042)
3.5	31.3	GO:0031995	insulin-like growth factor II binding(GO:0031995)
3.3	9.8	GO:0015203	ornithine decarboxylase inhibitor activity(GO:0008073) polyamine transmembrane transporter activity(GO:0015203) putrescine transmembrane transporter activity(GO:0015489)
3.2	19.1	GO:0008970	phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
2.9	8.8	GO:0015254	glycerol channel activity(GO:0015254)
2.6	7.9	GO:0004735	pyrroline-5-carboxylate reductase activity(GO:0004735)
2.5	14.9	GO:0004473	malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
2.4	7.2	GO:0004046	aminoacylase activity(GO:0004046)
2.3	11.4	GO:0031798	type 1 metabotropic glutamate receptor binding(GO:0031798)
2.2	6.7	GO:0031249	denatured protein binding(GO:0031249)
2.0	22.3	GO:0039706	co-receptor binding(GO:0039706)
2.0	11.7	GO:0005332	gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
1.9	17.1	GO:0086080	protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
1.9	9.5	GO:0004690	cyclic nucleotide-dependent protein kinase activity(GO:0004690)
1.8	10.7	GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
1.7	7.0	GO:0004459	L-lactate dehydrogenase activity(GO:0004459)
1.6	4.9	GO:0004833	tryptophan 2,3-dioxygenase activity(GO:0004833)
1.6	12.7	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
1.5	7.7	GO:0086062	voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
1.5	4.4	GO:0008396	oxysterol 7-alpha-hydroxylase activity(GO:0008396)
1.4	4.3	GO:0000179	rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
1.3	25.5	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
1.3	15.6	GO:0019869	chloride channel inhibitor activity(GO:0019869)
1.3	3.9	GO:0015141	succinate transmembrane transporter activity(GO:0015141)
1.3	5.1	GO:0004449	isocitrate dehydrogenase (NAD+) activity(GO:0004449)
1.2	3.6	GO:0016971	flavin-linked sulfhydryl oxidase activity(GO:0016971)
1.2	5.9	GO:0004945	angiotensin type II receptor activity(GO:0004945)
1.2	4.7	GO:0004897	ciliary neurotrophic factor receptor activity(GO:0004897)
1.2	15.0	GO:0030215	semaphorin receptor binding(GO:0030215)
1.1	7.8	GO:0001849	complement component C1q binding(GO:0001849)
1.1	19.9	GO:0043295	glutathione binding(GO:0043295)
1.1	4.2	GO:0042806	fucose binding(GO:0042806)
1.0	5.2	GO:0015220	choline transmembrane transporter activity(GO:0015220)
1.0	5.2	GO:0097016	L27 domain binding(GO:0097016)
1.0	5.1	GO:0004977	melanocortin receptor activity(GO:0004977)
1.0	13.3	GO:0005528	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
1.0	23.4	GO:0005242	inward rectifier potassium channel activity(GO:0005242)
1.0	10.0	GO:0019808	polyamine binding(GO:0019808)
1.0	2.9	GO:0050429	calcium-dependent phospholipase C activity(GO:0050429)
0.9	2.8	GO:0004069	L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.9	9.4	GO:0005412	glucose:sodium symporter activity(GO:0005412)
0.9	2.7	GO:0004775	succinate-CoA ligase activity(GO:0004774) succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.9	6.3	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.9	10.6	GO:0004032	alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.9	2.6	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.9	6.8	GO:0035374	chondroitin sulfate binding(GO:0035374)
0.8	22.7	GO:0031402	sodium ion binding(GO:0031402)
0.8	7.2	GO:0022833	mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.8	5.5	GO:0043426	MRF binding(GO:0043426)
0.8	9.2	GO:0102391	decanoate--CoA ligase activity(GO:0102391)
0.8	5.3	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.7	9.3	GO:0045499	chemorepellent activity(GO:0045499)
0.7	2.8	GO:0004656	procollagen-proline 4-dioxygenase activity(GO:0004656)
0.7	3.5	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.7	2.7	GO:0008109	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.7	6.6	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.7	4.0	GO:0004144	2-acylglycerol O-acyltransferase activity(GO:0003846) diacylglycerol O-acyltransferase activity(GO:0004144)
0.7	9.2	GO:0070679	inositol 1,4,5 trisphosphate binding(GO:0070679)
0.6	12.9	GO:0005328	neurotransmitter:sodium symporter activity(GO:0005328)
0.6	7.7	GO:0003747	translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.6	4.4	GO:1990226	histone methyltransferase binding(GO:1990226)
0.6	68.5	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.6	8.0	GO:0098919	structural constituent of postsynaptic specialization(GO:0098879) structural constituent of synapse(GO:0098918) structural constituent of postsynaptic density(GO:0098919)
0.6	3.6	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.6	6.9	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.6	3.3	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.5	2.7	GO:1990829	C-rich single-stranded DNA binding(GO:1990829)
0.5	2.1	GO:0004743	pyruvate kinase activity(GO:0004743)
0.5	5.2	GO:0015143	urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.5	3.0	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.5	16.1	GO:0019706	protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.5	1.4	GO:0033823	procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.5	3.3	GO:0015526	hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.5	5.5	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.5	5.0	GO:0030983	mismatched DNA binding(GO:0030983)
0.5	5.4	GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.4	7.1	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.4	13.3	GO:0004623	phospholipase A2 activity(GO:0004623)
0.4	6.2	GO:0033038	bitter taste receptor activity(GO:0033038)
0.4	1.8	GO:0044183	protein binding involved in protein folding(GO:0044183)
0.4	3.1	GO:0030957	Tat protein binding(GO:0030957)
0.4	6.9	GO:0070402	NADPH binding(GO:0070402)
0.4	14.2	GO:0017075	syntaxin-1 binding(GO:0017075)
0.4	6.0	GO:0017154	semaphorin receptor activity(GO:0017154)
0.4	30.2	GO:0019888	protein phosphatase regulator activity(GO:0019888)
0.4	4.6	GO:0005549	odorant binding(GO:0005549)
0.4	7.9	GO:0008179	adenylate cyclase binding(GO:0008179)
0.4	6.6	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.4	2.4	GO:0043237	laminin-1 binding(GO:0043237)
0.4	25.3	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
0.4	3.2	GO:0003996	acyl-CoA ligase activity(GO:0003996)
0.4	3.9	GO:0070324	thyroid hormone binding(GO:0070324)
0.4	1.2	GO:0008281	sulfonylurea receptor activity(GO:0008281)
0.4	2.2	GO:0051430	corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.4	1.4	GO:0005219	ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.4	1.8	GO:0004161	dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.3	5.1	GO:0004679	AMP-activated protein kinase activity(GO:0004679)
0.3	8.7	GO:0000062	fatty-acyl-CoA binding(GO:0000062)
0.3	5.7	GO:0097602	cullin family protein binding(GO:0097602)
0.3	2.7	GO:0003680	AT DNA binding(GO:0003680)
0.3	1.0	GO:0043812	phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.3	11.1	GO:0008536	Ran GTPase binding(GO:0008536)
0.3	1.9	GO:0090599	alpha-glucosidase activity(GO:0090599)
0.3	8.4	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.3	3.1	GO:0005132	type I interferon receptor binding(GO:0005132)
0.3	5.0	GO:0016671	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.3	1.8	GO:0047961	glycine N-acyltransferase activity(GO:0047961)
0.3	4.7	GO:0008195	phosphatidate phosphatase activity(GO:0008195)
0.3	8.1	GO:0004707	MAP kinase activity(GO:0004707)
0.3	7.2	GO:0008395	steroid hydroxylase activity(GO:0008395)
0.3	8.5	GO:0050699	WW domain binding(GO:0050699)
0.3	4.7	GO:0031996	thioesterase binding(GO:0031996)
0.3	5.2	GO:0008301	DNA binding, bending(GO:0008301)
0.3	0.5	GO:0004315	3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315)
0.3	6.1	GO:0001223	transcription coactivator binding(GO:0001223)
0.3	1.5	GO:0035242	protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.2	4.2	GO:0047617	acyl-CoA hydrolase activity(GO:0047617)
0.2	5.6	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
0.2	5.6	GO:0000030	mannosyltransferase activity(GO:0000030)
0.2	7.6	GO:0001540	beta-amyloid binding(GO:0001540)
0.2	11.2	GO:0098531	RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.2	1.8	GO:0008172	S-methyltransferase activity(GO:0008172) cobalamin binding(GO:0031419)
0.2	7.0	GO:0004407	histone deacetylase activity(GO:0004407)
0.2	0.8	GO:0017089	glycolipid transporter activity(GO:0017089)
0.2	0.8	GO:0070052	collagen V binding(GO:0070052)
0.2	5.3	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.2	1.7	GO:0015187	glycine transmembrane transporter activity(GO:0015187)
0.2	4.1	GO:0000983	transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.2	4.9	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.2	2.4	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)
0.2	3.2	GO:0017049	GTP-Rho binding(GO:0017049)
0.2	1.0	GO:0004994	somatostatin receptor activity(GO:0004994)
0.2	14.4	GO:0051082	unfolded protein binding(GO:0051082)
0.2	1.3	GO:0031432	titin binding(GO:0031432)
0.2	0.6	GO:0004784	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.2	4.5	GO:0016676	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.2	8.0	GO:0050840	extracellular matrix binding(GO:0050840)
0.1	1.3	GO:0043394	proteoglycan binding(GO:0043394)
0.1	1.9	GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1	29.9	GO:0000287	magnesium ion binding(GO:0000287)
0.1	7.0	GO:0051287	NAD binding(GO:0051287)
0.1	2.0	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.1	1.1	GO:0015217	ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.1	0.7	GO:0031781	melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.1	22.2	GO:0005516	calmodulin binding(GO:0005516)
0.1	0.8	GO:0016901	oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.1	5.3	GO:0016706	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.1	3.2	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1	7.5	GO:0051087	chaperone binding(GO:0051087)
0.1	1.6	GO:0016805	dipeptidase activity(GO:0016805)
0.1	3.1	GO:0008137	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1	3.4	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.1	2.5	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.1	7.4	GO:0008146	sulfotransferase activity(GO:0008146)
0.1	0.3	GO:0000991	transcription factor activity, core RNA polymerase II binding(GO:0000991)
0.1	0.8	GO:0015562	efflux transmembrane transporter activity(GO:0015562)
0.1	4.7	GO:0005080	protein kinase C binding(GO:0005080)
0.1	11.2	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.1	1.7	GO:0005212	structural constituent of eye lens(GO:0005212)
0.1	2.3	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1	3.4	GO:0031369	translation initiation factor binding(GO:0031369)
0.1	2.0	GO:0046961	proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1	2.0	GO:0035250	UDP-galactosyltransferase activity(GO:0035250)
0.1	8.7	GO:0016503	pheromone receptor activity(GO:0016503)
0.1	2.3	GO:0015020	glucuronosyltransferase activity(GO:0015020)
0.1	1.1	GO:0035198	miRNA binding(GO:0035198)
0.1	1.1	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.1	9.0	GO:0044325	ion channel binding(GO:0044325)
0.1	16.7	GO:0003729	mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.1	1.2	GO:0005521	lamin binding(GO:0005521)
0.1	1.0	GO:0003796	lysozyme activity(GO:0003796)
0.1	3.5	GO:0004812	aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.1	1.8	GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors(GO:0016645)
0.1	8.8	GO:0003774	motor activity(GO:0003774)
0.1	0.6	GO:0044548	S100 protein binding(GO:0044548)
0.1	2.6	GO:0001105	RNA polymerase II transcription coactivator activity(GO:0001105)
0.1	0.7	GO:0050811	GABA receptor binding(GO:0050811)
0.1	1.5	GO:0070006	metalloaminopeptidase activity(GO:0070006)
0.1	1.5	GO:0015175	neutral amino acid transmembrane transporter activity(GO:0015175)
0.1	1.7	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.1	1.9	GO:0030295	protein kinase activator activity(GO:0030295)
0.0	1.0	GO:0001106	RNA polymerase II transcription corepressor activity(GO:0001106)
0.0	0.6	GO:0051378	serotonin binding(GO:0051378)
0.0	3.5	GO:0004843	thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0	1.1	GO:0070003	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0	47.1	GO:0004984	olfactory receptor activity(GO:0004984)
0.0	1.0	GO:0005484	SNAP receptor activity(GO:0005484)
0.0	11.9	GO:0004842	ubiquitin-protein transferase activity(GO:0004842)
0.0	0.5	GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0	4.8	GO:0045296	cadherin binding(GO:0045296)
0.0	0.3	GO:0071855	neuropeptide receptor binding(GO:0071855)
0.0	0.5	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	1.1	GO:0016874	ligase activity(GO:0016874)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	27.7	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.5	5.6	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.5	9.3	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.5	11.7	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.3	11.8	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.3	5.1	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.3	11.4	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
0.3	4.4	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.3	7.4	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.3	13.8	PID ATR PATHWAY	ATR signaling pathway
0.3	3.3	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.3	12.5	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.3	23.8	ST INTEGRIN SIGNALING PATHWAY	Integrin Signaling Pathway
0.3	7.7	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.2	15.6	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.2	5.6	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.2	2.8	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.1	3.1	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1	29.2	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.1	5.2	ST JNK MAPK PATHWAY	JNK MAPK Pathway
0.1	1.8	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.1	5.1	PID LKB1 PATHWAY	LKB1 signaling events
0.1	3.1	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.1	3.3	PID CDC42 PATHWAY	CDC42 signaling events
0.1	1.6	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.1	0.8	PID FOXO PATHWAY	FoxO family signaling
0.1	2.0	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events
0.1	0.6	PID ALK2 PATHWAY	ALK2 signaling events
0.0	0.6	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
0.0	0.7	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.0	0.6	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	1.7	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.0	1.2	PID P53 REGULATION PATHWAY	p53 pathway
0.0	0.8	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.0	0.3	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.0	0.8	ST FAS SIGNALING PATHWAY	Fas Signaling Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.6	12.7	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
1.5	31.3	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
1.3	46.9	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.8	13.5	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.8	9.5	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.7	19.9	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.6	7.6	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.6	20.9	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.6	10.1	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.6	5.1	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.6	12.9	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.5	16.2	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.5	4.9	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.5	6.4	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.5	10.0	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.5	7.8	REACTOME AMYLOIDS	Genes involved in Amyloids
0.5	13.1	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS	Genes involved in CREB phosphorylation through the activation of Ras
0.5	17.6	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.4	6.8	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.4	5.3	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.4	26.5	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.3	5.2	REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.3	7.1	REACTOME CELL CELL JUNCTION ORGANIZATION	Genes involved in Cell-cell junction organization
0.3	5.1	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.3	7.0	REACTOME PYRUVATE METABOLISM	Genes involved in Pyruvate metabolism
0.3	10.0	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.3	8.7	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.3	7.0	REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS	Genes involved in Phase 1 - Functionalization of compounds
0.3	4.4	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.3	5.3	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.3	2.8	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.2	2.2	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.2	7.4	REACTOME TRIGLYCERIDE BIOSYNTHESIS	Genes involved in Triglyceride Biosynthesis
0.2	11.0	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
0.2	4.4	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.2	1.8	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.2	5.6	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.2	11.5	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.2	3.9	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.2	4.0	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.2	7.0	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.2	2.7	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.2	2.7	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.2	3.3	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.2	7.6	REACTOME REGULATION OF INSULIN SECRETION	Genes involved in Regulation of Insulin Secretion
0.1	2.0	REACTOME MEIOSIS	Genes involved in Meiosis
0.1	3.6	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1	8.7	REACTOME POTASSIUM CHANNELS	Genes involved in Potassium Channels
0.1	11.0	REACTOME SIGNALING BY PDGF	Genes involved in Signaling by PDGF
0.1	4.2	REACTOME PHASE II CONJUGATION	Genes involved in Phase II conjugation
0.1	2.0	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.1	1.7	REACTOME GLUCAGON TYPE LIGAND RECEPTORS	Genes involved in Glucagon-type ligand receptors
0.1	3.0	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.1	4.3	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.1	2.0	REACTOME TRNA AMINOACYLATION	Genes involved in tRNA Aminoacylation
0.1	1.8	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1	5.1	REACTOME G ALPHA S SIGNALLING EVENTS	Genes involved in G alpha (s) signalling events
0.1	4.2	REACTOME L1CAM INTERACTIONS	Genes involved in L1CAM interactions
0.1	1.4	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.0	1.5	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.6	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	4.7	REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES	Genes involved in Metabolism of amino acids and derivatives
0.0	1.8	REACTOME NUCLEAR SIGNALING BY ERBB4	Genes involved in Nuclear signaling by ERBB4
0.0	2.6	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0	1.0	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.4	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.0	1.4	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.0	0.3	REACTOME VIRAL MESSENGER RNA SYNTHESIS	Genes involved in Viral Messenger RNA Synthesis
0.0	0.3	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis

Results for Hsf2

Z-value: 1.04

Motif logo

Transcription factors associated with Hsf2

Activity-expression correlation:

Activity profile of Hsf2 motif

Sorted Z-values of Hsf2 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of Hsf2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: