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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Gcm2

Z-value: 1.98

Motif logo

Transcription factors associated with Gcm2

Gene Symbol Gene ID Gene Info
ENSRNOG00000015008 glial cells missing homolog 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Gcm2rn6_v1_chr17_+_21490402_214904020.511.7e-22Click!

Activity profile of Gcm2 motif

Sorted Z-values of Gcm2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr14_-_78707861 136.52 ENSRNOT00000091927
protein phosphatase 2, regulatory subunit B, gamma
chr14_-_86297623 134.39 ENSRNOT00000067162
ENSRNOT00000081607
ENSRNOT00000085265
calcium/calmodulin-dependent protein kinase II beta
chr3_-_11382004 71.94 ENSRNOT00000047921
ENSRNOT00000064039
dynamin 1
chr14_+_77380262 69.39 ENSRNOT00000008030
neuron specific gene family member 1
chr1_-_73753128 66.58 ENSRNOT00000068459
tweety family member 1
chr8_+_49441106 61.03 ENSRNOT00000030152
sodium voltage-gated channel beta subunit 4
chr6_+_92229686 58.48 ENSRNOT00000046085
atlastin GTPase 1
chr8_-_116893057 56.80 ENSRNOT00000082113
bassoon (presynaptic cytomatrix protein)
chr8_-_59226597 56.33 ENSRNOT00000088208
acyl-CoA synthetase bubblegum family member 1
chr5_+_140870140 52.34 ENSRNOT00000074347
hippocalcin-like 4
chr19_+_41482728 50.91 ENSRNOT00000022943
calbindin 2
chr18_+_79406381 49.51 ENSRNOT00000022303
ENSRNOT00000058295
ENSRNOT00000058296
ENSRNOT00000022280
myelin basic protein
chr10_-_15166457 48.55 ENSRNOT00000026676
meteorin, glial cell differentiation regulator
chr17_+_47397558 47.99 ENSRNOT00000085923
ependymin related 1
chr18_+_27632786 47.97 ENSRNOT00000073564
ENSRNOT00000078969
receptor accessory protein 2
chr17_-_27969433 46.57 ENSRNOT00000073967
neuritin 1
chr1_-_81881549 44.64 ENSRNOT00000027497
ATPase Na+/K+ transporting subunit alpha 3
chr1_-_103256823 44.54 ENSRNOT00000018860
protein tyrosine phosphatase, non-receptor type 5
chr2_+_198721724 44.13 ENSRNOT00000043535
ankyrin repeat domain 34A
chr20_-_1980101 43.71 ENSRNOT00000084582
ENSRNOT00000085050
ENSRNOT00000082545
ENSRNOT00000088396
gamma-aminobutyric acid type B receptor subunit 1
chr10_-_18574710 43.47 ENSRNOT00000079031
potassium voltage-gated channel interacting protein 1
chr17_-_18592750 43.22 ENSRNOT00000065742
CAP, adenylate cyclase-associated protein, 2 (yeast)
chr11_+_75905443 43.15 ENSRNOT00000002650
fibroblast growth factor 12
chr7_+_141346398 43.04 ENSRNOT00000077175
acid sensing ion channel subunit 1
chr10_-_18574909 42.92 ENSRNOT00000083090
potassium voltage-gated channel interacting protein 1
chr13_-_82753438 42.77 ENSRNOT00000075948
ATPase Na+/K+ transporting subunit beta 1
chr4_-_157078130 41.76 ENSRNOT00000015570
calsyntenin 3
chr3_-_168033457 40.47 ENSRNOT00000055111
breast carcinoma amplified sequence 1
chr16_-_79973735 39.77 ENSRNOT00000057845
ENSRNOT00000086896
DLG associated protein 2
chr12_+_14021727 39.30 ENSRNOT00000060608
monocyte to macrophage differentiation-associated 2
chr9_-_82477136 38.92 ENSRNOT00000026753
ENSRNOT00000089555
regulated endocrine-specific protein 18
chr13_+_77485113 38.61 ENSRNOT00000080254
tenascin R
chr3_-_102151489 38.59 ENSRNOT00000006349
anoctamin 3
chr1_-_198454914 38.35 ENSRNOT00000049044
proline-rich transmembrane protein 2
chr14_+_60764409 38.23 ENSRNOT00000005168
leucine-rich repeat LGI family, member 2
chr1_+_266952561 37.75 ENSRNOT00000076452
neuralized E3 ubiquitin protein ligase 1
chr1_+_81372650 36.88 ENSRNOT00000088829
zinc finger protein 428
chr5_-_105582375 36.79 ENSRNOT00000083373
solute carrier family 24 member 2
chr19_+_56220755 36.21 ENSRNOT00000023452
tubulin, beta 3 class III
chr12_+_47551935 36.15 ENSRNOT00000056932
RGD1560398
chr3_-_176816114 35.83 ENSRNOT00000079262
ENSRNOT00000018697
stathmin 3
chr10_-_61361250 35.54 ENSRNOT00000092203
RAP1 GTPase activating protein 2
chr3_+_177225737 35.33 ENSRNOT00000045845
opioid related nociceptin receptor 1
chr2_+_143475323 35.24 ENSRNOT00000044028
ENSRNOT00000015437
transient receptor potential cation channel, subfamily C, member 4
chr3_+_113319456 35.14 ENSRNOT00000051354
creatine kinase, mitochondrial 1
chr5_+_128501847 34.95 ENSRNOT00000010645
RAB3B, member RAS oncogene family
chr2_+_115678344 34.90 ENSRNOT00000036717
solute carrier family 7, member 14
chr16_+_20691978 34.89 ENSRNOT00000038139
ENSRNOT00000082319
transmembrane protein 59-like
chr4_-_89151184 34.83 ENSRNOT00000010263
nucleosome assembly protein 1-like 5
chrX_-_39956841 34.79 ENSRNOT00000050708
kelch-like family member 34
chr3_+_51687809 34.32 ENSRNOT00000087242
sodium voltage-gated channel alpha subunit 2
chr19_-_56311991 34.15 ENSRNOT00000014090
dysbindin domain containing 1
chr1_-_212548730 33.98 ENSRNOT00000089729
calcyon neuron-specific vesicular protein
chr3_-_105279462 33.33 ENSRNOT00000010679
secretogranin V
chr7_-_119441487 32.97 ENSRNOT00000067635
parvalbumin
chr1_+_214927172 32.91 ENSRNOT00000027134
BR serine/threonine kinase 2
chr8_-_40023193 32.37 ENSRNOT00000014404
neurogranin
chr4_+_22859622 32.32 ENSRNOT00000073501
ENSRNOT00000068410
ADAM metallopeptidase domain 22
chr8_-_58542844 32.29 ENSRNOT00000012041
ELMO domain containing 1
chr14_+_17534412 32.24 ENSRNOT00000079304
ENSRNOT00000046771
cyclin dependent kinase like 2
chr10_-_63952726 32.13 ENSRNOT00000090461
double C2 domain beta
chr14_+_6994190 32.12 ENSRNOT00000020357
SPARC like 1
chr15_-_37410848 32.10 ENSRNOT00000081757
gap junction protein, beta 6
chr5_+_164972480 31.77 ENSRNOT00000012670
F-box protein 2
chr7_+_139698148 31.43 ENSRNOT00000078579
phosphofructokinase, muscle
chr3_+_117416345 31.26 ENSRNOT00000056054
cortexin 2
chr7_-_29701586 30.99 ENSRNOT00000009084
ENSRNOT00000089269
anoctamin 4
chr4_-_71713063 30.95 ENSRNOT00000059447
family with sequence similarity 131, member B
chr3_+_177226417 30.73 ENSRNOT00000031328
opioid related nociceptin receptor 1
chr12_+_48316143 30.52 ENSRNOT00000084511
SV2 related protein
chr16_+_21061237 30.27 ENSRNOT00000092136
neurocan
chr16_+_67350539 30.12 ENSRNOT00000085659
ENSRNOT00000015879
unc-5 netrin receptor D
chr9_-_55673704 30.06 ENSRNOT00000066231
ENSRNOT00000081677
transmembrane protein with EGF-like and two follistatin-like domains 2
chr14_-_3389943 30.00 ENSRNOT00000037101
epoxide hydrolase 4
chr15_+_52148379 29.81 ENSRNOT00000074912
phytanoyl-CoA 2-hydroxylase interacting protein
chr7_-_117151256 29.72 ENSRNOT00000078846
nuclear receptor binding protein 2
chr13_+_90692666 29.69 ENSRNOT00000010028
immunoglobulin superfamily, member 8
chr2_+_144646308 29.59 ENSRNOT00000078337
ENSRNOT00000093407
doublecortin-like kinase 1
chr5_+_103479767 29.34 ENSRNOT00000008999
SH3 domain-containing GRB2-like 2
chr1_+_125367280 29.28 ENSRNOT00000022049
amyloid beta precursor protein binding family A member 2
chr1_+_72860218 29.19 ENSRNOT00000024547
synaptotagmin 5
chr10_+_80790168 28.83 ENSRNOT00000073315
ENSRNOT00000075163
carbonic anhydrase 10
chr18_+_73564247 28.83 ENSRNOT00000077679
ENSRNOT00000035317
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
chr8_+_56179816 28.64 ENSRNOT00000059078
Rho GTPase activating protein 20
chr8_-_98738446 28.62 ENSRNOT00000019860
Zic family member 1
chr13_-_52197205 28.52 ENSRNOT00000009712
shisa family member 4
chr3_+_58632476 28.48 ENSRNOT00000010630
Rap guanine nucleotide exchange factor 4
chr4_+_35279063 28.17 ENSRNOT00000011833
neurexophilin 1
chr2_+_121165137 27.96 ENSRNOT00000016236
SRY box 2
chr10_+_39655455 27.95 ENSRNOT00000058817
acyl-CoA synthetase long-chain family member 6
chr16_-_21089508 27.85 ENSRNOT00000072565
hyaluronan and proteoglycan link protein 4
chr4_-_108008484 27.56 ENSRNOT00000007971
catenin alpha 2
chr10_+_92191718 27.53 ENSRNOT00000006764
ENSRNOT00000032941
corticotropin releasing hormone receptor 1
chr1_-_42587666 27.50 ENSRNOT00000083225
ENSRNOT00000025355
regulator of G-protein signaling 17
chr3_+_110574417 27.49 ENSRNOT00000031231
dispatched RND transporter family member 2
chr4_-_4473307 27.32 ENSRNOT00000045773
dipeptidyl peptidase like 6
chr17_-_48562838 27.24 ENSRNOT00000017102
ENSRNOT00000084702
amphiphysin
chr2_+_228544418 27.22 ENSRNOT00000013030
translocation associated membrane protein 1-like 1
chr4_-_146016325 26.89 ENSRNOT00000067931
ATPase plasma membrane Ca2+ transporting 2
chr1_+_36185916 26.73 ENSRNOT00000041762
ubiquitin-conjugating enzyme E2Q family-like 1
chr16_-_59366824 26.46 ENSRNOT00000015062
similar to 6430573F11Rik protein
chr9_+_82647071 26.39 ENSRNOT00000027135
acid sensing ion channel subunit family member 4
chr7_-_126461658 26.25 ENSRNOT00000081032
wingless-type MMTV integration site family, member 7B
chr18_+_31094965 26.22 ENSRNOT00000026526
RELT-like 2
chr7_-_141185710 26.21 ENSRNOT00000085033
Fas apoptotic inhibitory molecule 2
chr2_-_172459165 26.10 ENSRNOT00000057473
schwannomin interacting protein 1
chr1_+_256955652 26.08 ENSRNOT00000020411
leucine-rich, glioma inactivated 1
chr19_+_6046665 26.07 ENSRNOT00000084126
cadherin 8
chr4_-_147163467 25.97 ENSRNOT00000010748
tissue inhibitor of metalloproteinase 4
chr12_+_41073824 25.90 ENSRNOT00000001844
rabphilin 3A
chr4_-_179307095 25.82 ENSRNOT00000021193
branched chain amino acid transaminase 1
chr14_+_66631690 25.50 ENSRNOT00000079658
potassium voltage-gated channel interacting protein 4
chr9_-_44237117 25.46 ENSRNOT00000068496
similar to putative protein (5S487)
chr4_-_64330996 25.38 ENSRNOT00000016088
pleiotrophin
chr13_+_101181994 25.25 ENSRNOT00000052407
sushi domain containing 4
chrX_+_23081125 25.23 ENSRNOT00000071639

chr5_-_40237591 25.21 ENSRNOT00000011393
fucosyltransferase 9
chr14_+_8182383 25.10 ENSRNOT00000092719
mitogen activated protein kinase 10
chrX_+_17171605 25.07 ENSRNOT00000048236
nudix (nucleoside diphosphate linked moiety X)-type motif 10
chr1_+_78029555 25.00 ENSRNOT00000047289
solute carrier family 8 member A2
chrX_+_105134498 24.89 ENSRNOT00000002058
transmembrane protein 35
chr3_-_52447622 24.89 ENSRNOT00000083552
sodium voltage-gated channel alpha subunit 1
chr6_+_79254339 24.75 ENSRNOT00000073970
somatostatin receptor 1
chr6_+_83083740 24.47 ENSRNOT00000007600
leucine rich repeat and fibronectin type III domain containing 5
chr10_+_102136283 24.27 ENSRNOT00000003735
somatostatin receptor 2
chr1_-_88908750 24.20 ENSRNOT00000028297
amyloid beta precursor like protein 1
chr9_+_17841410 24.17 ENSRNOT00000031706
transmembrane protein 151B
chr1_-_220502272 23.87 ENSRNOT00000041238
kinesin light chain 2
chr4_+_438668 23.83 ENSRNOT00000008951
engrailed homeobox 2
chr3_+_56861396 23.72 ENSRNOT00000000008
ENSRNOT00000084375
glutamate decarboxylase 1
chr5_-_82168347 23.72 ENSRNOT00000084959
ENSRNOT00000084147
astrotactin 2
chr2_+_220298245 23.70 ENSRNOT00000022625
phospholipid phosphatase related 4
chr12_-_35979193 23.68 ENSRNOT00000071104
transmembrane protein 132B
chr18_-_86878142 23.60 ENSRNOT00000058139
docking protein 6
chrX_+_62727755 23.54 ENSRNOT00000077055
phosphate cytidylyltransferase 1, choline, beta
chr3_+_48106099 23.50 ENSRNOT00000007218
solute carrier family 4 member 10
chr8_+_56179637 23.31 ENSRNOT00000035989
Rho GTPase activating protein 20
chr12_-_22680630 23.30 ENSRNOT00000041808
VGF nerve growth factor inducible
chr13_+_67351087 23.27 ENSRNOT00000003567
prostaglandin-endoperoxide synthase 2
chrX_+_39711201 23.26 ENSRNOT00000080512
ENSRNOT00000009802
connector enhancer of kinase suppressor of Ras 2
chr2_+_115337439 23.08 ENSRNOT00000015779
eukaryotic translation initiation factor 5A2
chr8_-_117382715 23.02 ENSRNOT00000027466
prolyl 4-hydroxylase, transmembrane
chr13_+_84474319 23.00 ENSRNOT00000031367
ENSRNOT00000072244
ENSRNOT00000072897
ENSRNOT00000064168
ENSRNOT00000074954
ENSRNOT00000073696
immunoglobulin-like domain containing receptor 2
chr2_+_27905535 22.84 ENSRNOT00000022120
family with sequence similarity 169, member A
chr14_-_78377825 22.81 ENSRNOT00000068104

chr8_+_118333706 22.67 ENSRNOT00000028278
chondroitin sulfate proteoglycan 5
chr2_-_198184739 22.64 ENSRNOT00000028751
vacuolar protein sorting 45
chr1_-_52544450 22.62 ENSRNOT00000043474
phosphodiesterase 10A
chr16_-_7007287 22.58 ENSRNOT00000041216
inter-alpha trypsin inhibitor, heavy chain 3
chr8_-_84632817 22.50 ENSRNOT00000076942
muscular LMNA-interacting protein
chr20_+_7279820 22.48 ENSRNOT00000090820
protein kinase C and casein kinase substrate in neurons 1
chr20_+_5815837 22.48 ENSRNOT00000036999
lipoma HMGIC fusion partner-like 5
chr10_+_75055020 22.44 ENSRNOT00000010755
TSPO associated protein 1
chr12_-_10391270 21.99 ENSRNOT00000092340
WAS protein family, member 3
chr3_-_147849875 21.87 ENSRNOT00000081153
neurensin 2
chr6_+_107596782 21.80 ENSRNOT00000076882
dynein, axonemal, light chain 1
chr8_+_65611570 21.71 ENSRNOT00000017147
La ribonucleoprotein domain family, member 6
chr16_-_7007051 21.65 ENSRNOT00000023984
inter-alpha trypsin inhibitor, heavy chain 3
chr11_+_86512797 21.65 ENSRNOT00000051680
glycoprotein Ib platelet beta subunit
chr5_-_170679315 21.63 ENSRNOT00000071459
adherens junctions associated protein 1
chr5_-_109651730 21.53 ENSRNOT00000093032
ELAV like RNA binding protein 2
chr6_+_26797126 21.46 ENSRNOT00000010586
cell growth regulator with EF hand domain 1
chr2_-_188561267 21.45 ENSRNOT00000089781
ENSRNOT00000092093
tripartite motif-containing 46
chr9_-_114619711 21.44 ENSRNOT00000050012
microtubule crosslinking factor 1
chr5_+_139790395 21.43 ENSRNOT00000015033
regulating synaptic membrane exocytosis 3
chr16_+_20297414 21.39 ENSRNOT00000025576
solute carrier family 5 member 5
chr12_-_29743705 21.24 ENSRNOT00000001185
calneuron 1
chr10_-_103340922 21.04 ENSRNOT00000004191
BTB domain containing 17
chr10_+_58342393 21.03 ENSRNOT00000010358
WSC domain containing 1
chr7_-_72328128 21.02 ENSRNOT00000008227
TSPY-like 5
chr6_-_98157087 21.01 ENSRNOT00000013275
potassium voltage-gated channel subfamily H member 5
chr5_-_138267601 20.99 ENSRNOT00000008726
transmembrane protein 269
chr13_-_80379929 20.96 ENSRNOT00000067653
ENSRNOT00000075938
dynamin 3
chr16_+_54765325 20.85 ENSRNOT00000065327
ENSRNOT00000086899
myotubularin related protein 7
chrX_+_127562660 20.75 ENSRNOT00000029031
ENSRNOT00000010367
glutamate ionotropic receptor AMPA type subunit 3
chr14_-_82055290 20.64 ENSRNOT00000058062
RGD1560394
chr8_-_91338843 20.56 ENSRNOT00000012999
ELOVL fatty acid elongase 4
chrX_+_157150655 20.50 ENSRNOT00000090795
pregnancy up-regulated nonubiquitous CaM kinase
chr4_-_43096399 20.49 ENSRNOT00000087167
cortactin binding protein 2
chr4_-_55407922 20.47 ENSRNOT00000031714
glutamate metabotropic receptor 8
chr4_+_168976859 20.38 ENSRNOT00000068663
family with sequence similarity 234, member B
chr15_-_47442664 20.31 ENSRNOT00000072994
protease, serine, 55
chr1_-_125967756 20.30 ENSRNOT00000031488
family with sequence similarity 189, member A1
chr10_-_51576376 20.27 ENSRNOT00000004829
Rho GTPase activating protein 44
chr8_-_47094352 20.26 ENSRNOT00000048347
glutamate ionotropic receptor kainate type subunit 4
chr7_+_141326950 20.15 ENSRNOT00000084075
acid sensing ion channel subunit 1
chrX_+_106523278 20.06 ENSRNOT00000070802
similar to Microsomal signal peptidase 23 kDa subunit (SPase 22 kDa subunit) (SPC22/23)
chr5_+_146337491 20.00 ENSRNOT00000029395
UPF0500 protein C1orf216 homolog
chr7_-_13751271 19.90 ENSRNOT00000009931
solute carrier family 1 member 6
chr6_+_97110158 19.85 ENSRNOT00000088430
synaptotagmin 16
chr12_+_28381982 19.78 ENSRNOT00000076101
Williams-Beuren syndrome chromosome region 17
chr10_-_36322356 19.72 ENSRNOT00000000248
zinc finger protein 354C
chr2_-_96668222 19.64 ENSRNOT00000016567
cAMP-dependent protein kinase inhibitor alpha
chr1_-_263269762 19.64 ENSRNOT00000022309
glutamic-oxaloacetic transaminase 1
chr18_+_62852303 19.64 ENSRNOT00000087673
G protein subunit alpha L
chr10_+_59585072 19.64 ENSRNOT00000025009
calcium/calmodulin-dependent protein kinase kinase 1
chr8_+_82288705 19.58 ENSRNOT00000012409
BCL2 like 10
chr5_-_85123829 19.48 ENSRNOT00000007578
BMP/retinoic acid inducible neural specific 1
chr10_+_55940533 19.47 ENSRNOT00000012061
similar to RIKEN cDNA A030009H04
chr11_+_34598492 19.35 ENSRNOT00000065600
tetratricopeptide repeat domain 3

Network of associatons between targets according to the STRING database.

First level regulatory network of Gcm2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
44.8 134.4 GO:0032430 positive regulation of phospholipase A2 activity(GO:0032430)
16.5 66.1 GO:1904059 regulation of locomotor rhythm(GO:1904059)
16.5 49.5 GO:1904207 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209) positive regulation of metalloendopeptidase activity(GO:1904685)
15.2 91.3 GO:0098887 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887)
14.3 42.8 GO:1903281 positive regulation of calcium:sodium antiporter activity(GO:1903281)
13.3 92.9 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
13.2 79.1 GO:0099526 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
11.6 69.6 GO:0061588 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
11.3 56.3 GO:0001552 ovarian follicle atresia(GO:0001552)
10.2 61.2 GO:0014053 negative regulation of gamma-aminobutyric acid secretion(GO:0014053)
9.3 27.9 GO:0010747 positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747)
9.2 27.5 GO:0051867 general adaptation syndrome, behavioral process(GO:0051867)
9.2 55.0 GO:0038170 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
9.0 63.2 GO:0050915 sensory perception of sour taste(GO:0050915)
8.9 151.5 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
8.8 35.0 GO:1904373 response to kainic acid(GO:1904373)
8.7 26.2 GO:0072054 renal outer medulla development(GO:0072054)
8.7 35.0 GO:0051582 positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
8.6 43.2 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
8.6 25.8 GO:0009098 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
8.4 25.3 GO:0045959 negative regulation of complement activation, classical pathway(GO:0045959)
7.9 31.4 GO:0061622 glycolytic process through glucose-1-phosphate(GO:0061622)
7.8 23.3 GO:0035633 maintenance of blood-brain barrier(GO:0035633)
7.4 44.5 GO:2001025 positive regulation of response to drug(GO:2001025)
7.1 28.5 GO:1901423 response to benzene(GO:1901423)
7.0 28.0 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
6.5 19.6 GO:0006532 fumarate metabolic process(GO:0006106) aspartate biosynthetic process(GO:0006532) aspartate catabolic process(GO:0006533)
6.3 19.0 GO:0002086 diaphragm contraction(GO:0002086)
6.3 37.7 GO:0048686 regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)
6.3 25.1 GO:1901908 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
6.1 60.9 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)
6.0 6.0 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
5.9 23.7 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
5.9 52.8 GO:0071436 sodium ion export(GO:0071436)
5.8 17.4 GO:0021629 muscle attachment(GO:0016203) olfactory nerve morphogenesis(GO:0021627) olfactory nerve structural organization(GO:0021629)
5.8 17.3 GO:0006713 glucocorticoid catabolic process(GO:0006713)
5.7 17.0 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
5.7 17.0 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
5.5 71.9 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
5.5 33.2 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
5.3 48.0 GO:0032596 protein transport into membrane raft(GO:0032596) sensory perception of sweet taste(GO:0050916)
5.3 42.6 GO:0031547 brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
5.2 15.7 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
5.2 15.5 GO:2000681 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
5.2 15.5 GO:0034635 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
5.1 15.2 GO:1900453 negative regulation of long term synaptic depression(GO:1900453)
5.0 15.1 GO:0055129 L-proline biosynthetic process(GO:0055129)
5.0 30.1 GO:0045113 regulation of integrin biosynthetic process(GO:0045113)
4.9 24.3 GO:0019521 aldonic acid metabolic process(GO:0019520) D-gluconate metabolic process(GO:0019521)
4.8 14.5 GO:0001546 preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162)
4.7 18.8 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
4.6 13.9 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
4.6 18.4 GO:0051643 endoplasmic reticulum localization(GO:0051643)
4.6 13.8 GO:0018201 peptidyl-glycine modification(GO:0018201)
4.6 18.4 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)
4.5 45.2 GO:0046710 GDP metabolic process(GO:0046710)
4.5 17.8 GO:0043179 rhythmic excitation(GO:0043179)
4.4 26.6 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
4.3 13.0 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
4.3 21.4 GO:2000574 regulation of microtubule motor activity(GO:2000574)
4.2 29.4 GO:0000160 phosphorelay signal transduction system(GO:0000160)
4.1 20.6 GO:0034626 fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
4.1 16.3 GO:0051081 membrane disassembly(GO:0030397) nuclear envelope disassembly(GO:0051081)
4.0 83.5 GO:0050884 neuromuscular process controlling posture(GO:0050884)
4.0 51.5 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
3.9 11.8 GO:0002877 regulation of acute inflammatory response to non-antigenic stimulus(GO:0002877)
3.9 11.6 GO:1904708 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748) granulosa cell apoptotic process(GO:1904700) regulation of granulosa cell apoptotic process(GO:1904708)
3.8 23.1 GO:0045901 regulation of translational termination(GO:0006449) positive regulation of translational elongation(GO:0045901)
3.8 11.5 GO:0003050 regulation of systemic arterial blood pressure by atrial natriuretic peptide(GO:0003050)
3.8 19.1 GO:0071930 negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
3.8 3.8 GO:0035262 gonad morphogenesis(GO:0035262)
3.8 56.9 GO:0007288 sperm axoneme assembly(GO:0007288)
3.7 29.3 GO:0016191 synaptic vesicle uncoating(GO:0016191)
3.7 11.0 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
3.6 3.6 GO:1902956 regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902956)
3.6 18.2 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
3.6 18.1 GO:0043400 cortisol secretion(GO:0043400) regulation of cortisol secretion(GO:0051462)
3.6 17.9 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
3.6 14.2 GO:0003219 cardiac right ventricle formation(GO:0003219)
3.5 10.6 GO:0046952 ketone body catabolic process(GO:0046952)
3.5 14.2 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
3.5 59.2 GO:0045760 positive regulation of action potential(GO:0045760)
3.4 20.4 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
3.4 61.0 GO:0086027 AV node cell action potential(GO:0086016) AV node cell to bundle of His cell signaling(GO:0086027)
3.4 13.5 GO:0033227 dsRNA transport(GO:0033227)
3.4 13.5 GO:1902514 regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
3.3 36.4 GO:0099612 protein localization to axon(GO:0099612)
3.3 13.1 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
3.3 9.8 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
3.2 26.0 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
3.2 32.0 GO:0042866 pyruvate biosynthetic process(GO:0042866)
3.2 16.0 GO:0006564 L-serine biosynthetic process(GO:0006564)
3.1 9.4 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
3.0 30.5 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
3.0 9.1 GO:0072061 inner medullary collecting duct development(GO:0072061)
3.0 59.1 GO:0021859 pyramidal neuron differentiation(GO:0021859)
2.9 29.1 GO:0002098 tRNA wobble uridine modification(GO:0002098)
2.9 11.6 GO:0016103 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
2.9 31.8 GO:0006465 signal peptide processing(GO:0006465)
2.9 17.3 GO:0032286 central nervous system myelin maintenance(GO:0032286)
2.9 23.0 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
2.9 8.6 GO:0051977 lysophospholipid transport(GO:0051977)
2.9 14.3 GO:0035934 corticosterone secretion(GO:0035934)
2.9 5.7 GO:0060024 rhythmic synaptic transmission(GO:0060024)
2.8 19.6 GO:0009405 pathogenesis(GO:0009405)
2.8 25.0 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
2.8 11.1 GO:0052651 monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
2.8 11.1 GO:2000277 positive regulation of oxidative phosphorylation uncoupler activity(GO:2000277)
2.8 5.5 GO:0006114 glycerol biosynthetic process(GO:0006114) alditol biosynthetic process(GO:0019401)
2.8 13.8 GO:0006868 glutamine transport(GO:0006868)
2.7 13.6 GO:0001579 medium-chain fatty acid transport(GO:0001579)
2.7 13.5 GO:0043985 histone H4-R3 methylation(GO:0043985)
2.7 2.7 GO:0097324 melanocyte migration(GO:0097324)
2.6 5.2 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
2.6 23.5 GO:1904116 response to vasopressin(GO:1904116)
2.6 10.4 GO:0002035 brain renin-angiotensin system(GO:0002035)
2.6 7.8 GO:0003330 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
2.6 147.5 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
2.6 28.4 GO:0007258 JUN phosphorylation(GO:0007258)
2.5 10.2 GO:0000966 RNA 5'-end processing(GO:0000966)
2.5 22.7 GO:0015705 iodide transport(GO:0015705)
2.5 7.4 GO:0060060 post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
2.5 7.4 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
2.5 24.6 GO:0060013 righting reflex(GO:0060013)
2.4 19.3 GO:1901620 regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901620)
2.4 4.8 GO:0014057 positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
2.4 16.7 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
2.4 11.8 GO:0030311 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
2.3 9.4 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
2.3 35.2 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
2.3 14.0 GO:0006572 tyrosine catabolic process(GO:0006572)
2.3 9.2 GO:2000813 negative regulation of barbed-end actin filament capping(GO:2000813)
2.3 18.4 GO:0015808 L-alanine transport(GO:0015808)
2.3 11.5 GO:0044571 [2Fe-2S] cluster assembly(GO:0044571)
2.3 6.9 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
2.3 16.0 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
2.3 4.6 GO:0051012 microtubule sliding(GO:0051012)
2.3 6.8 GO:0006382 adenosine to inosine editing(GO:0006382) regulation of RNA interference(GO:1900368)
2.3 25.0 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
2.3 4.5 GO:0072076 nephrogenic mesenchyme development(GO:0072076)
2.2 4.5 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
2.1 34.0 GO:0048268 clathrin coat assembly(GO:0048268)
2.1 6.3 GO:0010070 zygote asymmetric cell division(GO:0010070)
2.1 4.2 GO:0035607 ventricular zone neuroblast division(GO:0021847) fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development(GO:0035607)
2.1 6.2 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
2.1 33.1 GO:1900273 positive regulation of long-term synaptic potentiation(GO:1900273)
2.0 26.5 GO:0046069 cGMP catabolic process(GO:0046069)
2.0 6.1 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
2.0 16.1 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
2.0 8.0 GO:1904220 regulation of serine C-palmitoyltransferase activity(GO:1904220)
2.0 4.0 GO:0021836 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836)
1.9 5.8 GO:0001880 Mullerian duct regression(GO:0001880)
1.9 17.3 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
1.9 20.7 GO:0007614 short-term memory(GO:0007614)
1.9 26.2 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694)
1.9 7.5 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
1.9 16.8 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
1.9 20.5 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
1.9 3.7 GO:0038108 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
1.9 5.6 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
1.9 20.4 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
1.9 5.6 GO:0071896 protein localization to adherens junction(GO:0071896)
1.8 9.2 GO:0090261 positive regulation of inclusion body assembly(GO:0090261)
1.8 9.2 GO:0060080 inhibitory postsynaptic potential(GO:0060080)
1.8 16.4 GO:0042756 drinking behavior(GO:0042756)
1.8 5.4 GO:0019389 glucuronoside metabolic process(GO:0019389)
1.8 16.3 GO:0045636 positive regulation of melanocyte differentiation(GO:0045636)
1.8 70.1 GO:0046839 phospholipid dephosphorylation(GO:0046839)
1.8 10.6 GO:0033564 anterior/posterior axon guidance(GO:0033564)
1.7 8.7 GO:1904781 positive regulation of protein localization to centrosome(GO:1904781)
1.7 29.5 GO:0006516 glycoprotein catabolic process(GO:0006516)
1.7 51.6 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
1.7 49.8 GO:0060292 long term synaptic depression(GO:0060292)
1.7 18.6 GO:1901538 DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
1.7 6.7 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
1.7 6.7 GO:2000630 positive regulation of miRNA metabolic process(GO:2000630)
1.7 23.3 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
1.7 19.9 GO:0001964 startle response(GO:0001964)
1.6 1.6 GO:1905232 cellular response to L-glutamate(GO:1905232)
1.6 21.0 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
1.6 41.7 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
1.6 8.0 GO:0009972 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
1.6 6.3 GO:0036438 maintenance of lens transparency(GO:0036438)
1.6 117.4 GO:0050772 positive regulation of axonogenesis(GO:0050772)
1.6 4.7 GO:0032066 nucleolus to nucleoplasm transport(GO:0032066)
1.5 3.1 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
1.5 6.1 GO:0052422 modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
1.5 19.9 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
1.5 4.5 GO:0036112 medium-chain fatty-acyl-CoA metabolic process(GO:0036112) fatty-acyl-CoA catabolic process(GO:0036115)
1.5 1.5 GO:1903044 protein localization to membrane raft(GO:1903044)
1.5 31.5 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
1.5 12.0 GO:0060717 chorion development(GO:0060717)
1.5 16.4 GO:0016486 peptide hormone processing(GO:0016486)
1.5 14.8 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
1.5 2.9 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
1.5 13.2 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
1.4 7.2 GO:0090258 negative regulation of mitochondrial fission(GO:0090258) response to hypobaric hypoxia(GO:1990910)
1.4 4.3 GO:0090669 telomerase RNA stabilization(GO:0090669)
1.4 15.8 GO:1990403 embryonic brain development(GO:1990403)
1.4 7.1 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719)
1.4 4.3 GO:0003357 noradrenergic neuron differentiation(GO:0003357)
1.4 7.1 GO:0090494 catecholamine uptake(GO:0090493) dopamine uptake(GO:0090494)
1.4 7.1 GO:0010529 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
1.4 11.0 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
1.4 5.5 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
1.3 4.0 GO:0019541 acetate metabolic process(GO:0006083) propionate metabolic process(GO:0019541)
1.3 36.2 GO:0045761 regulation of adenylate cyclase activity(GO:0045761)
1.3 23.3 GO:0043084 penile erection(GO:0043084)
1.3 3.9 GO:1990022 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
1.3 25.5 GO:0008210 estrogen metabolic process(GO:0008210)
1.3 17.8 GO:0034587 piRNA metabolic process(GO:0034587)
1.3 1.3 GO:0006408 snRNA export from nucleus(GO:0006408)
1.3 10.1 GO:0060591 chondroblast differentiation(GO:0060591)
1.2 15.0 GO:2000009 negative regulation of protein localization to cell surface(GO:2000009)
1.2 5.0 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
1.2 17.2 GO:0036065 fucosylation(GO:0036065)
1.2 4.9 GO:0031642 negative regulation of myelination(GO:0031642)
1.2 2.4 GO:0051866 general adaptation syndrome(GO:0051866)
1.2 8.4 GO:0006598 polyamine catabolic process(GO:0006598)
1.2 6.0 GO:0006842 tricarboxylic acid transport(GO:0006842)
1.2 2.4 GO:0045634 regulation of melanocyte differentiation(GO:0045634)
1.2 21.3 GO:0010107 potassium ion import(GO:0010107)
1.2 7.0 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
1.2 4.7 GO:0046379 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
1.2 18.6 GO:0045475 locomotor rhythm(GO:0045475)
1.2 2.3 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
1.1 26.1 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
1.1 10.2 GO:0043031 negative regulation of macrophage activation(GO:0043031)
1.1 7.9 GO:0033572 transferrin transport(GO:0033572)
1.1 4.5 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
1.1 10.1 GO:0008090 retrograde axonal transport(GO:0008090)
1.1 3.3 GO:0014827 intestine smooth muscle contraction(GO:0014827)
1.1 11.1 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
1.1 7.7 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
1.1 4.4 GO:0071468 cellular response to acidic pH(GO:0071468)
1.1 3.3 GO:1902512 positive regulation of apoptotic DNA fragmentation(GO:1902512) positive regulation of DNA catabolic process(GO:1903626)
1.1 16.4 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
1.1 16.4 GO:0021680 cerebellar Purkinje cell layer development(GO:0021680)
1.1 2.2 GO:1904350 regulation of protein catabolic process in the vacuole(GO:1904350)
1.1 3.3 GO:1903719 regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
1.1 1.1 GO:0009182 purine deoxyribonucleoside diphosphate metabolic process(GO:0009182) dGDP metabolic process(GO:0046066)
1.1 3.2 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
1.0 3.1 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
1.0 55.0 GO:1901379 regulation of potassium ion transmembrane transport(GO:1901379)
1.0 3.0 GO:0034643 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
1.0 11.1 GO:0090051 negative regulation of cell migration involved in sprouting angiogenesis(GO:0090051)
1.0 8.0 GO:0042135 neurotransmitter catabolic process(GO:0042135)
1.0 43.8 GO:0007029 endoplasmic reticulum organization(GO:0007029)
1.0 7.8 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
1.0 49.5 GO:0046579 positive regulation of Ras protein signal transduction(GO:0046579)
1.0 2.9 GO:0009794 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
1.0 2.9 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
1.0 10.6 GO:0033139 regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033139) positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
1.0 12.5 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
1.0 5.7 GO:0032264 IMP salvage(GO:0032264)
0.9 2.8 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.9 2.8 GO:2001038 regulation of cellular response to drug(GO:2001038)
0.9 6.5 GO:1901374 acetate ester transport(GO:1901374)
0.9 3.7 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.9 13.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.9 0.9 GO:1901079 positive regulation of relaxation of muscle(GO:1901079)
0.9 20.8 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.9 19.9 GO:0097503 sialylation(GO:0097503)
0.9 5.4 GO:0016559 peroxisome fission(GO:0016559)
0.9 9.7 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.9 2.6 GO:0000965 mitochondrial RNA 3'-end processing(GO:0000965)
0.9 3.5 GO:0044778 meiotic DNA integrity checkpoint(GO:0044778)
0.9 4.4 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.9 6.1 GO:0030818 negative regulation of cAMP biosynthetic process(GO:0030818)
0.9 3.4 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.8 11.0 GO:0031643 positive regulation of myelination(GO:0031643)
0.8 7.5 GO:0045945 positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.8 5.8 GO:0045631 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.8 51.6 GO:0050806 positive regulation of synaptic transmission(GO:0050806)
0.8 2.5 GO:0051697 protein delipidation(GO:0051697)
0.8 6.6 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.8 6.6 GO:0006670 sphingosine metabolic process(GO:0006670)
0.8 47.9 GO:0008589 regulation of smoothened signaling pathway(GO:0008589)
0.8 21.7 GO:1990138 neuron projection extension(GO:1990138)
0.8 2.4 GO:0009158 ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.8 4.8 GO:0090385 regulation of lysosomal lumen pH(GO:0035751) phagosome-lysosome fusion(GO:0090385)
0.8 2.4 GO:0060689 cell differentiation involved in salivary gland development(GO:0060689)
0.8 12.5 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.8 8.6 GO:0071625 vocalization behavior(GO:0071625)
0.8 23.2 GO:2001240 negative regulation of signal transduction in absence of ligand(GO:1901099) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.8 10.0 GO:0042407 cristae formation(GO:0042407)
0.8 1.5 GO:0032917 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918) spermine acetylation(GO:0032919)
0.8 1.5 GO:0009249 protein lipoylation(GO:0009249)
0.7 5.2 GO:0005513 detection of calcium ion(GO:0005513)
0.7 4.4 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.7 2.2 GO:0006788 heme oxidation(GO:0006788)
0.7 2.1 GO:0033026 negative regulation of mast cell apoptotic process(GO:0033026)
0.7 3.5 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.7 5.5 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.7 10.4 GO:0043496 regulation of protein homodimerization activity(GO:0043496)
0.7 34.5 GO:0046847 filopodium assembly(GO:0046847)
0.7 4.1 GO:0046836 glycolipid transport(GO:0046836)
0.7 17.7 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.7 2.7 GO:0031179 peptide modification(GO:0031179)
0.7 2.7 GO:0061370 testosterone biosynthetic process(GO:0061370)
0.7 2.0 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.7 0.7 GO:0034724 DNA replication-independent nucleosome organization(GO:0034724)
0.6 21.4 GO:0021762 substantia nigra development(GO:0021762)
0.6 3.8 GO:0014010 Schwann cell proliferation(GO:0014010)
0.6 1.9 GO:1900095 random inactivation of X chromosome(GO:0060816) regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.6 4.4 GO:0042118 endothelial cell activation(GO:0042118)
0.6 1.9 GO:0042350 GDP-L-fucose biosynthetic process(GO:0042350) GDP-L-fucose metabolic process(GO:0046368)
0.6 16.3 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.6 4.4 GO:0018095 protein polyglutamylation(GO:0018095)
0.6 25.9 GO:0008333 endosome to lysosome transport(GO:0008333)
0.6 6.2 GO:0002857 positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.6 5.5 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.6 1.8 GO:0070947 neutrophil mediated killing of gram-positive bacterium(GO:0070946) neutrophil mediated killing of fungus(GO:0070947)
0.6 2.4 GO:0032099 negative regulation of appetite(GO:0032099)
0.6 2.4 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.6 1.8 GO:2000118 regulation of sodium-dependent phosphate transport(GO:2000118)
0.6 25.5 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.6 8.9 GO:1901663 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.6 8.8 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.6 18.0 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.6 10.4 GO:0006450 regulation of translational fidelity(GO:0006450)
0.6 2.9 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.6 15.0 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.6 8.0 GO:0001675 acrosome assembly(GO:0001675)
0.6 21.6 GO:0031103 axon regeneration(GO:0031103)
0.6 1.1 GO:0007418 ventral midline development(GO:0007418)
0.6 20.2 GO:0008088 axo-dendritic transport(GO:0008088)
0.6 5.0 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.6 2.8 GO:0039689 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.6 23.7 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.5 2.7 GO:0035063 nuclear speck organization(GO:0035063)
0.5 17.6 GO:0018345 protein palmitoylation(GO:0018345)
0.5 11.9 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.5 9.7 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.5 9.1 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.5 3.2 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.5 1.6 GO:0030920 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.5 4.6 GO:0008063 Toll signaling pathway(GO:0008063)
0.5 2.6 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.5 6.1 GO:0051382 kinetochore assembly(GO:0051382)
0.5 5.5 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086)
0.5 34.1 GO:0032091 negative regulation of protein binding(GO:0032091)
0.5 45.1 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.5 2.0 GO:1901318 negative regulation of sperm motility(GO:1901318)
0.5 3.5 GO:0045650 negative regulation of macrophage differentiation(GO:0045650)
0.5 6.8 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.5 15.0 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.5 7.1 GO:0010667 negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.5 6.6 GO:0060122 inner ear receptor stereocilium organization(GO:0060122)
0.5 36.0 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.5 9.6 GO:0048588 developmental cell growth(GO:0048588)
0.5 2.3 GO:0030953 astral microtubule organization(GO:0030953)
0.4 2.6 GO:0007341 penetration of zona pellucida(GO:0007341)
0.4 3.0 GO:0032288 myelin assembly(GO:0032288)
0.4 1.3 GO:0035128 post-embryonic appendage morphogenesis(GO:0035120) post-embryonic limb morphogenesis(GO:0035127) post-embryonic forelimb morphogenesis(GO:0035128) telomeric repeat-containing RNA transcription(GO:0097393) telomeric repeat-containing RNA transcription from RNA pol II promoter(GO:0097394) regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901580) negative regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901581) positive regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901582)
0.4 12.7 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.4 2.1 GO:0071386 cellular response to corticosterone stimulus(GO:0071386)
0.4 4.6 GO:0051481 negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.4 4.2 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.4 2.5 GO:0022417 protein maturation by protein folding(GO:0022417)
0.4 2.0 GO:0022007 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.4 1.2 GO:0071376 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.4 1.6 GO:0046519 sphingoid metabolic process(GO:0046519)
0.4 12.6 GO:0051693 actin filament capping(GO:0051693)
0.4 3.1 GO:0061734 parkin-mediated mitophagy in response to mitochondrial depolarization(GO:0061734)
0.4 6.9 GO:0046621 negative regulation of organ growth(GO:0046621)
0.4 3.0 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.4 12.8 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.4 0.7 GO:1990839 response to endothelin(GO:1990839) cellular response to endothelin(GO:1990859)
0.4 2.2 GO:0034184 positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.4 31.2 GO:0048813 dendrite morphogenesis(GO:0048813)
0.4 2.2 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.4 14.0 GO:0007416 synapse assembly(GO:0007416)
0.4 15.3 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.4 1.4 GO:0052314 phytoalexin metabolic process(GO:0052314)
0.3 1.4 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
0.3 0.7 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.3 1.7 GO:0001927 exocyst assembly(GO:0001927)
0.3 2.7 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.3 11.7 GO:0006695 cholesterol biosynthetic process(GO:0006695)
0.3 1.7 GO:0060023 soft palate development(GO:0060023)
0.3 1.0 GO:0090481 pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.3 2.3 GO:0043097 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.3 1.6 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.3 3.1 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.3 5.9 GO:0061098 positive regulation of protein tyrosine kinase activity(GO:0061098)
0.3 1.5 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.3 2.1 GO:0035608 protein deglutamylation(GO:0035608)
0.3 0.9 GO:0046061 dATP catabolic process(GO:0046061)
0.3 1.8 GO:0015874 norepinephrine transport(GO:0015874) norepinephrine secretion(GO:0048243)
0.3 17.0 GO:0022900 electron transport chain(GO:0022900)
0.3 2.0 GO:0016139 glycoside catabolic process(GO:0016139)
0.3 0.9 GO:0031989 bombesin receptor signaling pathway(GO:0031989)
0.3 2.8 GO:0031507 heterochromatin assembly(GO:0031507)
0.3 7.0 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.3 0.8 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.3 2.2 GO:0090267 positive regulation of spindle checkpoint(GO:0090232) positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.3 2.1 GO:0006527 arginine catabolic process(GO:0006527)
0.3 10.2 GO:0030521 androgen receptor signaling pathway(GO:0030521)
0.3 1.0 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.3 2.0 GO:1904869 protein localization to nuclear body(GO:1903405) positive regulation of establishment of protein localization to telomere(GO:1904851) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) protein localization to nucleoplasm(GO:1990173)
0.3 2.3 GO:0006198 cAMP catabolic process(GO:0006198) cyclic nucleotide catabolic process(GO:0009214)
0.3 14.0 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.3 23.8 GO:0006334 nucleosome assembly(GO:0006334)
0.2 1.9 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.2 0.2 GO:0016576 histone dephosphorylation(GO:0016576)
0.2 1.6 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.2 1.9 GO:0061635 regulation of protein complex stability(GO:0061635)
0.2 17.4 GO:0008361 regulation of cell size(GO:0008361)
0.2 0.2 GO:0070948 regulation of neutrophil mediated cytotoxicity(GO:0070948) regulation of neutrophil mediated killing of symbiont cell(GO:0070949)
0.2 3.3 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.2 4.1 GO:0031577 mitotic spindle assembly checkpoint(GO:0007094) spindle checkpoint(GO:0031577) spindle assembly checkpoint(GO:0071173) mitotic spindle checkpoint(GO:0071174)
0.2 2.1 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.2 3.4 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.2 2.8 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.2 1.7 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.2 0.6 GO:0006431 methionyl-tRNA aminoacylation(GO:0006431)
0.2 0.4 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.2 1.0 GO:0015889 cobalamin transport(GO:0015889)
0.2 5.0 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.2 0.4 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.2 1.3 GO:0060613 fat pad development(GO:0060613)
0.2 1.3 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.2 6.1 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.2 7.3 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.2 3.1 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.2 26.3 GO:0007409 axonogenesis(GO:0007409)
0.2 1.9 GO:0015868 purine nucleotide transport(GO:0015865) purine ribonucleotide transport(GO:0015868)
0.2 3.3 GO:0001522 pseudouridine synthesis(GO:0001522)
0.2 3.3 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.1 1.2 GO:0000012 single strand break repair(GO:0000012)
0.1 3.2 GO:0030901 midbrain development(GO:0030901)
0.1 1.9 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 1.1 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.1 5.7 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.1 3.3 GO:0070741 response to interleukin-6(GO:0070741)
0.1 4.7 GO:0045454 cell redox homeostasis(GO:0045454)
0.1 6.6 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.1 1.2 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.1 1.3 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.1 0.3 GO:0045337 geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384) farnesyl diphosphate biosynthetic process(GO:0045337) farnesyl diphosphate metabolic process(GO:0045338)
0.1 1.1 GO:0035404 histone-serine phosphorylation(GO:0035404)
0.1 6.5 GO:0071805 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.1 2.4 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.1 1.9 GO:0051602 response to electrical stimulus(GO:0051602)
0.1 0.2 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
0.1 2.0 GO:0060976 coronary vasculature development(GO:0060976)
0.1 0.8 GO:0044821 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.1 0.5 GO:1902031 regulation of NADP metabolic process(GO:1902031)
0.1 0.4 GO:2000171 negative regulation of dendrite development(GO:2000171)
0.1 0.3 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.1 0.7 GO:0021591 ventricular system development(GO:0021591)
0.1 0.6 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.1 0.3 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.0 0.0 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.0 0.6 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.7 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.7 GO:0000154 rRNA modification(GO:0000154)
0.0 0.7 GO:0032011 ARF protein signal transduction(GO:0032011)
0.0 0.6 GO:0048240 sperm capacitation(GO:0048240)
0.0 46.3 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.8 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.8 GO:0006270 DNA replication initiation(GO:0006270)
0.0 1.6 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0 0.4 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.0 GO:0016598 protein arginylation(GO:0016598)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
24.8 74.4 GO:1990257 piccolo-bassoon transport vesicle(GO:1990257)
14.6 43.7 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
13.9 69.4 GO:0098845 postsynaptic endosome(GO:0098845)
13.3 66.6 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
13.1 65.6 GO:1990769 proximal neuron projection(GO:1990769)
10.5 31.4 GO:0005945 6-phosphofructokinase complex(GO:0005945)
9.8 58.8 GO:0044326 dendritic spine neck(GO:0044326)
9.7 48.7 GO:0072534 perineuronal net(GO:0072534)
9.4 65.6 GO:0000137 Golgi cis cisterna(GO:0000137)
8.3 49.5 GO:0033269 internode region of axon(GO:0033269)
7.9 23.7 GO:0060187 cell pole(GO:0060187)
7.8 38.9 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
6.7 53.3 GO:0044327 dendritic spine head(GO:0044327)
6.1 18.4 GO:0042642 actomyosin, myosin complex part(GO:0042642)
6.0 120.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
5.7 28.5 GO:0044316 cone cell pedicle(GO:0044316)
5.6 151.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
5.3 31.8 GO:0005787 signal peptidase complex(GO:0005787)
4.9 19.4 GO:0097427 microtubule bundle(GO:0097427)
4.8 19.2 GO:0045298 tubulin complex(GO:0045298)
4.6 161.7 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
4.5 27.0 GO:0097441 basilar dendrite(GO:0097441)
4.5 44.8 GO:1990635 proximal dendrite(GO:1990635)
4.3 17.3 GO:0070436 Grb2-EGFR complex(GO:0070436)
3.9 42.8 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
3.7 18.5 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
3.4 10.2 GO:1990923 PET complex(GO:1990923)
3.4 20.3 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
3.4 67.1 GO:0043196 varicosity(GO:0043196)
3.3 45.8 GO:0043083 synaptic cleft(GO:0043083)
3.2 19.1 GO:0035189 Rb-E2F complex(GO:0035189)
3.1 86.6 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
3.0 26.9 GO:0098839 postsynaptic density membrane(GO:0098839)
2.8 14.2 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
2.7 24.3 GO:0071821 FANCM-MHF complex(GO:0071821)
2.7 43.0 GO:0005883 neurofilament(GO:0005883)
2.6 7.8 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
2.6 10.3 GO:0097196 Shu complex(GO:0097196)
2.5 7.6 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
2.4 64.1 GO:0043204 perikaryon(GO:0043204)
2.2 6.5 GO:0030121 AP-1 adaptor complex(GO:0030121)
2.2 8.7 GO:0044308 axonal spine(GO:0044308)
2.1 6.4 GO:0005668 RNA polymerase transcription factor SL1 complex(GO:0005668)
2.1 6.4 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
2.1 94.2 GO:0048786 presynaptic active zone(GO:0048786)
2.1 12.5 GO:0071547 piP-body(GO:0071547)
2.0 16.3 GO:0005869 dynactin complex(GO:0005869)
2.0 209.2 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
1.9 11.1 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
1.8 5.5 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
1.8 16.1 GO:0032591 dendritic spine membrane(GO:0032591)
1.7 6.8 GO:0044393 microspike(GO:0044393)
1.7 18.5 GO:0030673 axolemma(GO:0030673)
1.7 16.5 GO:0008290 F-actin capping protein complex(GO:0008290)
1.6 8.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
1.6 3.3 GO:0000322 storage vacuole(GO:0000322)
1.6 16.2 GO:0008091 spectrin(GO:0008091)
1.6 22.5 GO:0032426 stereocilium tip(GO:0032426)
1.6 23.9 GO:0035253 ciliary rootlet(GO:0035253)
1.6 4.7 GO:0030690 Noc1p-Noc2p complex(GO:0030690)
1.5 10.7 GO:0061617 MICOS complex(GO:0061617)
1.5 11.8 GO:0030915 Smc5-Smc6 complex(GO:0030915)
1.5 113.6 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
1.5 45.1 GO:0005921 gap junction(GO:0005921)
1.4 4.3 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
1.4 7.0 GO:0071203 WASH complex(GO:0071203)
1.4 5.6 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
1.4 9.7 GO:0031045 dense core granule(GO:0031045)
1.3 15.8 GO:0060091 kinocilium(GO:0060091)
1.3 67.0 GO:0034704 calcium channel complex(GO:0034704)
1.3 14.2 GO:0071564 npBAF complex(GO:0071564)
1.3 52.3 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
1.2 79.6 GO:0005881 cytoplasmic microtubule(GO:0005881)
1.2 601.7 GO:0098794 postsynapse(GO:0098794)
1.2 2.4 GO:0010009 cytoplasmic side of endosome membrane(GO:0010009)
1.2 22.9 GO:0044295 axonal growth cone(GO:0044295)
1.2 7.0 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
1.1 5.7 GO:0044530 supraspliceosomal complex(GO:0044530)
1.1 3.4 GO:0005962 mitochondrial isocitrate dehydrogenase complex (NAD+)(GO:0005962) isocitrate dehydrogenase complex (NAD+)(GO:0045242)
1.1 5.5 GO:0002142 stereocilia ankle link complex(GO:0002142)
1.1 7.7 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
1.1 5.5 GO:0070695 FHF complex(GO:0070695)
1.0 5.2 GO:0097452 GAIT complex(GO:0097452)
1.0 3.1 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
1.0 9.4 GO:0000813 ESCRT I complex(GO:0000813)
1.0 53.2 GO:0043195 terminal bouton(GO:0043195)
0.9 9.3 GO:0016600 flotillin complex(GO:0016600)
0.8 3.3 GO:0070761 pre-snoRNP complex(GO:0070761)
0.8 6.4 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.8 5.5 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.8 10.9 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.8 9.2 GO:0032589 neuron projection membrane(GO:0032589)
0.8 3.0 GO:0035339 SPOTS complex(GO:0035339)
0.8 3.8 GO:0005828 kinetochore microtubule(GO:0005828)
0.8 248.0 GO:0045202 synapse(GO:0045202)
0.7 3.7 GO:1990716 axonemal central apparatus(GO:1990716)
0.7 16.1 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.7 7.3 GO:0030008 TRAPP complex(GO:0030008)
0.7 66.5 GO:0030427 site of polarized growth(GO:0030427)
0.7 15.4 GO:0019013 viral nucleocapsid(GO:0019013)
0.7 50.9 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.7 15.0 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.6 7.1 GO:0035631 CD40 receptor complex(GO:0035631)
0.6 7.9 GO:0000124 SAGA complex(GO:0000124)
0.6 7.2 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.6 11.7 GO:0043679 axon terminus(GO:0043679)
0.6 3.5 GO:0030896 checkpoint clamp complex(GO:0030896)
0.6 1.7 GO:0045025 mitochondrial degradosome(GO:0045025)
0.6 3.9 GO:0030991 intraciliary transport particle A(GO:0030991)
0.5 1.6 GO:0042585 germinal vesicle(GO:0042585)
0.5 11.4 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.5 12.4 GO:0030992 intraciliary transport particle B(GO:0030992)
0.5 7.9 GO:0036038 MKS complex(GO:0036038)
0.5 251.6 GO:0043005 neuron projection(GO:0043005)
0.5 2.8 GO:0071565 nBAF complex(GO:0071565)
0.4 2.2 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.4 6.6 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.4 5.6 GO:0034709 methylosome(GO:0034709)
0.4 1.3 GO:1990707 subtelomeric heterochromatin(GO:1990421) nuclear subtelomeric heterochromatin(GO:1990707)
0.4 6.3 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.4 5.3 GO:0045495 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.4 7.6 GO:0000145 exocyst(GO:0000145)
0.4 2.8 GO:0045179 apical cortex(GO:0045179)
0.4 2.8 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.4 3.5 GO:0033391 chromatoid body(GO:0033391)
0.4 4.2 GO:0043202 lysosomal lumen(GO:0043202)
0.4 5.7 GO:0005682 U5 snRNP(GO:0005682)
0.4 2.2 GO:0034464 BBSome(GO:0034464)
0.4 8.0 GO:0002080 acrosomal membrane(GO:0002080)
0.4 16.5 GO:0016592 mediator complex(GO:0016592)
0.4 2.8 GO:0005677 chromatin silencing complex(GO:0005677)
0.3 1.7 GO:0034455 t-UTP complex(GO:0034455)
0.3 15.0 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.3 4.2 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.3 14.6 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.3 5.1 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.3 1.9 GO:0044754 autolysosome(GO:0044754)
0.3 6.6 GO:0034451 centriolar satellite(GO:0034451)
0.3 20.3 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.3 2.3 GO:0030891 VCB complex(GO:0030891)
0.2 1.2 GO:1990130 Iml1 complex(GO:1990130)
0.2 1.6 GO:0031415 NatA complex(GO:0031415)
0.2 1.7 GO:0005732 small nucleolar ribonucleoprotein complex(GO:0005732)
0.2 4.5 GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.2 6.4 GO:0008180 COP9 signalosome(GO:0008180)
0.2 4.4 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.2 3.1 GO:0031201 SNARE complex(GO:0031201)
0.2 2.8 GO:0000421 autophagosome membrane(GO:0000421)
0.2 22.3 GO:0005802 trans-Golgi network(GO:0005802)
0.2 2.0 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.2 3.2 GO:0035686 sperm fibrous sheath(GO:0035686)
0.2 52.6 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.2 1.8 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.2 5.1 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.2 1.8 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.2 3.6 GO:0042629 mast cell granule(GO:0042629)
0.1 1.4 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.1 1.2 GO:0000439 core TFIIH complex(GO:0000439)
0.1 1.3 GO:0043218 compact myelin(GO:0043218)
0.1 25.4 GO:0030141 secretory granule(GO:0030141)
0.1 0.8 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 1.0 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 1.5 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.1 0.8 GO:0000815 ESCRT III complex(GO:0000815)
0.1 2.1 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 5.3 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 7.0 GO:0043209 myelin sheath(GO:0043209)
0.1 2.2 GO:0005876 spindle microtubule(GO:0005876)
0.1 1.7 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 0.6 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.1 0.4 GO:0016282 eukaryotic 43S preinitiation complex(GO:0016282) eukaryotic 48S preinitiation complex(GO:0033290)
0.0 0.3 GO:0005655 nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.0 2.5 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.8 GO:1902562 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 2.0 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 1.7 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.1 GO:0035363 histone locus body(GO:0035363)
0.0 0.1 GO:0005675 holo TFIIH complex(GO:0005675)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
22.2 66.6 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
21.1 63.2 GO:0044736 acid-sensing ion channel activity(GO:0044736)
17.2 103.4 GO:0032051 clathrin light chain binding(GO:0032051)
13.6 81.6 GO:0031749 D2 dopamine receptor binding(GO:0031749)
11.0 66.1 GO:0004985 opioid receptor activity(GO:0004985)
10.9 43.7 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
10.6 74.4 GO:0045503 dynein light chain binding(GO:0045503)
9.6 28.8 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
9.2 55.0 GO:0004994 somatostatin receptor activity(GO:0004994)
8.7 26.2 GO:1902379 chemoattractant activity involved in axon guidance(GO:1902379)
8.6 25.8 GO:0004084 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
8.0 32.0 GO:0004743 pyruvate kinase activity(GO:0004743)
7.9 31.4 GO:0003872 6-phosphofructokinase activity(GO:0003872)
7.6 61.0 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
7.5 22.4 GO:0030156 benzodiazepine receptor binding(GO:0030156)
7.4 29.6 GO:0015056 corticotrophin-releasing factor receptor activity(GO:0015056) corticotropin-releasing hormone receptor activity(GO:0043404)
7.3 29.1 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
7.1 49.5 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
6.8 33.9 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
6.7 26.9 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
6.7 46.9 GO:0004111 creatine kinase activity(GO:0004111)
6.5 19.6 GO:0080130 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
6.5 149.9 GO:0043274 phospholipase binding(GO:0043274)
6.3 25.4 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
6.3 25.1 GO:0034431 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
6.2 87.4 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
6.1 18.4 GO:0008281 sulfonylurea receptor activity(GO:0008281)
6.1 72.8 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
6.0 24.2 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
6.0 18.0 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
5.9 23.7 GO:0004351 glutamate decarboxylase activity(GO:0004351)
5.9 23.7 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
5.3 21.4 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
5.1 20.5 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
5.0 15.1 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
5.0 15.0 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
4.9 48.7 GO:0042577 lipid phosphatase activity(GO:0042577)
4.8 14.5 GO:0005302 L-tyrosine transmembrane transporter activity(GO:0005302)
4.8 19.2 GO:0099609 microtubule lateral binding(GO:0099609)
4.7 23.7 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
4.7 33.1 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
4.7 61.5 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
4.7 23.5 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
4.6 18.5 GO:0055100 adiponectin binding(GO:0055100)
4.3 42.6 GO:0004385 guanylate kinase activity(GO:0004385)
4.2 29.4 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
4.1 20.7 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
4.0 72.1 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
3.9 19.6 GO:0089720 caspase binding(GO:0089720)
3.8 26.6 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
3.8 26.5 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
3.7 52.4 GO:0008179 adenylate cyclase binding(GO:0008179)
3.7 11.0 GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
3.6 43.8 GO:0019911 structural constituent of myelin sheath(GO:0019911)
3.5 10.5 GO:0097363 protein O-GlcNAc transferase activity(GO:0097363)
3.5 59.2 GO:0031402 sodium ion binding(GO:0031402)
3.5 10.4 GO:0102390 mycophenolic acid acyl-glucuronide esterase activity(GO:0102390)
3.4 13.8 GO:0000293 ferric-chelate reductase activity(GO:0000293)
3.4 13.8 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
3.4 20.5 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
3.4 20.3 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
3.3 9.9 GO:0042610 CD8 receptor binding(GO:0042610)
3.1 9.2 GO:0031531 thyrotropin-releasing hormone receptor binding(GO:0031531)
3.1 12.2 GO:0008489 UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity(GO:0008489)
3.0 11.8 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
2.9 38.0 GO:0050321 tau-protein kinase activity(GO:0050321)
2.9 20.3 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
2.9 17.2 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
2.8 28.4 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
2.7 46.6 GO:0070300 phosphatidic acid binding(GO:0070300)
2.7 76.7 GO:0005540 hyaluronic acid binding(GO:0005540)
2.7 13.5 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
2.6 21.1 GO:0004966 galanin receptor activity(GO:0004966)
2.6 21.0 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
2.6 18.3 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
2.6 10.4 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
2.6 141.1 GO:0015459 potassium channel regulator activity(GO:0015459)
2.5 10.2 GO:0034584 piRNA binding(GO:0034584)
2.5 9.9 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
2.4 23.5 GO:0022821 potassium ion antiporter activity(GO:0022821)
2.3 21.0 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
2.3 13.8 GO:0004308 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
2.3 4.5 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
2.2 17.8 GO:0016413 O-acetyltransferase activity(GO:0016413)
2.2 20.1 GO:0051022 Rho GDP-dissociation inhibitor binding(GO:0051022)
2.2 143.0 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
2.2 6.5 GO:1901375 acetylcholine transmembrane transporter activity(GO:0005277) acetate ester transmembrane transporter activity(GO:1901375)
2.1 10.7 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
2.1 10.6 GO:0005042 netrin receptor activity(GO:0005042)
2.1 16.8 GO:0005095 GTPase inhibitor activity(GO:0005095)
2.1 20.6 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
2.1 8.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
2.1 8.2 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
2.0 24.4 GO:0004000 adenosine deaminase activity(GO:0004000)
2.0 4.0 GO:0003987 acetate-CoA ligase activity(GO:0003987)
2.0 8.0 GO:0043495 protein anchor(GO:0043495)
1.9 62.3 GO:0017080 sodium channel regulator activity(GO:0017080)
1.9 9.6 GO:0004969 histamine receptor activity(GO:0004969)
1.9 7.5 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
1.8 7.4 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
1.8 16.6 GO:0050998 nitric-oxide synthase binding(GO:0050998)
1.8 7.3 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
1.8 10.9 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
1.8 7.1 GO:0050682 AF-2 domain binding(GO:0050682)
1.7 12.1 GO:0001595 angiotensin receptor activity(GO:0001595)
1.7 46.2 GO:0030742 GTP-dependent protein binding(GO:0030742)
1.7 20.4 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
1.6 4.9 GO:0052724 inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
1.6 9.7 GO:0070061 fructose binding(GO:0070061)
1.6 4.8 GO:0022841 potassium ion leak channel activity(GO:0022841)
1.6 6.3 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
1.6 9.5 GO:0015651 quaternary ammonium group transmembrane transporter activity(GO:0015651)
1.6 103.2 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
1.6 7.8 GO:0005329 dopamine transmembrane transporter activity(GO:0005329) dopamine:sodium symporter activity(GO:0005330)
1.5 15.4 GO:0042923 neuropeptide binding(GO:0042923)
1.5 16.6 GO:0008046 axon guidance receptor activity(GO:0008046)
1.5 6.0 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
1.5 3.0 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
1.5 17.8 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
1.5 4.4 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
1.5 58.0 GO:0005246 calcium channel regulator activity(GO:0005246)
1.4 5.7 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
1.4 22.7 GO:0035198 miRNA binding(GO:0035198)
1.4 11.3 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
1.4 9.7 GO:0016901 oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
1.3 5.4 GO:0015057 thrombin receptor activity(GO:0015057)
1.3 6.7 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
1.3 5.4 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
1.3 21.4 GO:0016918 retinal binding(GO:0016918)
1.3 8.0 GO:0004126 cytidine deaminase activity(GO:0004126)
1.3 19.9 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313)
1.3 4.0 GO:0015180 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
1.3 5.2 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
1.3 2.6 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
1.3 37.5 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
1.3 32.0 GO:0030552 cAMP binding(GO:0030552)
1.3 21.5 GO:0043008 ATP-dependent protein binding(GO:0043008)
1.2 16.1 GO:0008061 chitin binding(GO:0008061)
1.2 11.1 GO:0005347 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
1.2 22.1 GO:0052866 phosphatidylinositol phosphate phosphatase activity(GO:0052866)
1.2 7.3 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
1.2 6.0 GO:0015142 tricarboxylic acid transmembrane transporter activity(GO:0015142)
1.2 4.7 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
1.2 7.0 GO:0003923 GPI-anchor transamidase activity(GO:0003923) GPI anchor binding(GO:0034235)
1.2 10.6 GO:0005132 type I interferon receptor binding(GO:0005132)
1.2 3.5 GO:0042296 ISG15 transferase activity(GO:0042296)
1.2 8.1 GO:0071532 ankyrin repeat binding(GO:0071532)
1.2 31.2 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
1.1 9.2 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
1.1 4.6 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
1.1 13.6 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
1.1 7.8 GO:0005173 stem cell factor receptor binding(GO:0005173)
1.1 21.3 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
1.1 36.8 GO:0001540 beta-amyloid binding(GO:0001540)
1.1 32.1 GO:0005184 neuropeptide hormone activity(GO:0005184)
1.1 5.5 GO:0004477 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
1.1 10.9 GO:0004526 ribonuclease P activity(GO:0004526)
1.1 8.6 GO:0034603 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
1.1 5.3 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
1.1 7.4 GO:0045504 dynein heavy chain binding(GO:0045504)
1.1 3.2 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
1.0 4.2 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
1.0 13.5 GO:0004089 carbonate dehydratase activity(GO:0004089)
1.0 7.1 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
1.0 3.0 GO:0016403 dimethylargininase activity(GO:0016403)
1.0 11.9 GO:0042809 vitamin D receptor binding(GO:0042809)
1.0 7.9 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
1.0 6.7 GO:0001163 RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
1.0 11.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.9 17.0 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.9 2.8 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263)
0.9 45.7 GO:0035254 glutamate receptor binding(GO:0035254)
0.9 4.7 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.9 5.6 GO:0030957 Tat protein binding(GO:0030957)
0.9 22.2 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.9 5.5 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.9 5.5 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.9 11.8 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.9 42.2 GO:0045182 translation regulator activity(GO:0045182)
0.9 4.4 GO:0070739 protein-glutamic acid ligase activity(GO:0070739)
0.9 26.7 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.9 16.3 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.8 3.4 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.8 32.8 GO:0005158 insulin receptor binding(GO:0005158)
0.8 15.9 GO:0051010 microtubule plus-end binding(GO:0051010)
0.8 5.0 GO:0071253 connexin binding(GO:0071253)
0.8 12.0 GO:0032794 GTPase activating protein binding(GO:0032794)
0.8 5.5 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.8 10.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.8 17.3 GO:0003746 translation elongation factor activity(GO:0003746)
0.8 3.1 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.7 7.4 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.7 6.6 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.7 2.2 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.7 2.1 GO:0005135 interleukin-3 receptor binding(GO:0005135)
0.7 70.7 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.7 12.1 GO:0001671 ATPase activator activity(GO:0001671)
0.7 2.8 GO:0017089 glycolipid transporter activity(GO:0017089)
0.7 5.0 GO:0031685 adenosine receptor binding(GO:0031685)
0.7 9.7 GO:0051378 serotonin binding(GO:0051378)
0.7 2.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.7 2.7 GO:0016842 amidine-lyase activity(GO:0016842)
0.6 9.7 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.6 4.5 GO:0008422 beta-glucosidase activity(GO:0008422)
0.6 2.6 GO:0010465 nerve growth factor receptor activity(GO:0010465) G-protein coupled neurotensin receptor activity(GO:0016492)
0.6 17.2 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.6 3.8 GO:0017040 ceramidase activity(GO:0017040)
0.6 3.2 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.6 21.0 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.6 3.1 GO:0001155 TFIIIA-class transcription factor binding(GO:0001155)
0.6 3.0 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.6 5.5 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.6 2.4 GO:0043262 adenosine-diphosphatase activity(GO:0043262)
0.6 7.0 GO:0030215 semaphorin receptor binding(GO:0030215)
0.6 12.9 GO:0070840 dynein complex binding(GO:0070840)
0.6 7.0 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.6 4.1 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.6 4.6 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.6 15.9 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.6 12.3 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.5 15.2 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.5 8.7 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.5 9.1 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.5 3.2 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.5 3.2 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.5 8.5 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.5 1.6 GO:1990190 peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.5 6.3 GO:0015215 nucleotide transmembrane transporter activity(GO:0015215)
0.5 6.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.5 2.1 GO:0035673 lipid-transporting ATPase activity(GO:0034040) oligopeptide transmembrane transporter activity(GO:0035673)
0.5 6.2 GO:0017154 semaphorin receptor activity(GO:0017154)
0.5 5.7 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.5 2.6 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.5 1.5 GO:0008254 3'-nucleotidase activity(GO:0008254)
0.5 5.0 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.5 14.8 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.5 6.9 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.5 7.3 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.5 1.4 GO:0004058 aromatic-L-amino-acid decarboxylase activity(GO:0004058) L-dopa decarboxylase activity(GO:0036468)
0.5 8.0 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.5 1.4 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.5 0.9 GO:0050659 N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659)
0.5 1.4 GO:0015101 organic cation transmembrane transporter activity(GO:0015101)
0.5 1.4 GO:0033142 progesterone receptor binding(GO:0033142)
0.5 2.7 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.5 3.2 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.5 4.1 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.5 2.3 GO:0004849 uridine kinase activity(GO:0004849)
0.5 1.4 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.4 3.1 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.4 7.1 GO:0070403 NAD+ binding(GO:0070403)
0.4 2.2 GO:1990459 transferrin receptor binding(GO:1990459)
0.4 1.7 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.4 3.3 GO:0015925 galactosidase activity(GO:0015925)
0.4 2.5 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.4 6.1 GO:0005522 profilin binding(GO:0005522)
0.4 7.7 GO:0008171 O-methyltransferase activity(GO:0008171)
0.4 1.2 GO:0032564 dATP binding(GO:0032564)
0.4 5.1 GO:0070097 delta-catenin binding(GO:0070097)
0.4 10.5 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.4 208.5 GO:0005509 calcium ion binding(GO:0005509)
0.4 5.7 GO:0097602 cullin family protein binding(GO:0097602)
0.4 6.0 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.4 6.0 GO:0004659 prenyltransferase activity(GO:0004659)
0.4 8.6 GO:0043015 gamma-tubulin binding(GO:0043015)
0.4 9.4 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.4 16.7 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.4 6.6 GO:0005212 structural constituent of eye lens(GO:0005212)
0.4 90.4 GO:0005096 GTPase activator activity(GO:0005096)
0.4 6.2 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.4 6.9 GO:0004623 phospholipase A2 activity(GO:0004623)
0.4 24.3 GO:0044325 ion channel binding(GO:0044325)
0.4 1.1 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
0.4 1.1 GO:0031013 troponin I binding(GO:0031013)
0.3 12.7 GO:0008081 phosphoric diester hydrolase activity(GO:0008081)
0.3 5.1 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.3 14.2 GO:0019894 kinesin binding(GO:0019894)
0.3 3.6 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.3 72.8 GO:0015631 tubulin binding(GO:0015631)
0.3 1.3 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.3 32.3 GO:0005178 integrin binding(GO:0005178)
0.3 4.1 GO:0003796 lysozyme activity(GO:0003796)
0.3 30.9 GO:0016503 pheromone receptor activity(GO:0016503)
0.3 1.8 GO:0097322 7SK snRNA binding(GO:0097322)
0.3 0.9 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.3 1.5 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
0.3 7.8 GO:0070412 R-SMAD binding(GO:0070412)
0.3 6.0 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.3 1.6 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.3 9.2 GO:0009055 electron carrier activity(GO:0009055)
0.3 1.8 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.3 0.8 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.3 1.3 GO:0015616 DNA translocase activity(GO:0015616)
0.3 1.8 GO:0008430 selenium binding(GO:0008430)
0.2 4.4 GO:0008483 transaminase activity(GO:0008483)
0.2 4.4 GO:0099589 G-protein coupled serotonin receptor activity(GO:0004993) serotonin receptor activity(GO:0099589)
0.2 7.3 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.2 4.0 GO:0070034 telomerase RNA binding(GO:0070034)
0.2 0.6 GO:0004825 methionine-tRNA ligase activity(GO:0004825)
0.2 0.8 GO:0042289 MHC class II protein binding(GO:0042289)
0.2 1.2 GO:1990226 histone methyltransferase binding(GO:1990226)
0.2 1.0 GO:0031419 cobalamin binding(GO:0031419)
0.2 2.0 GO:0017136 NAD-dependent histone deacetylase activity(GO:0017136) histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) NAD-dependent protein deacetylase activity(GO:0034979)
0.2 0.8 GO:0002046 opsin binding(GO:0002046)
0.2 2.1 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.2 1.7 GO:0015266 protein channel activity(GO:0015266)
0.2 1.2 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.2 0.5 GO:0008948 oxaloacetate decarboxylase activity(GO:0008948)
0.2 1.0 GO:0016936 galactoside binding(GO:0016936)
0.2 1.0 GO:0004549 tRNA-specific ribonuclease activity(GO:0004549)
0.2 4.6 GO:0051018 protein kinase A binding(GO:0051018)
0.1 1.6 GO:0042165 neurotransmitter binding(GO:0042165)
0.1 2.9 GO:0050681 androgen receptor binding(GO:0050681)
0.1 2.3 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.1 0.7 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 28.7 GO:0003924 GTPase activity(GO:0003924)
0.1 12.0 GO:0005496 steroid binding(GO:0005496)
0.1 1.9 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 9.5 GO:0051082 unfolded protein binding(GO:0051082)
0.1 1.7 GO:0017160 Ral GTPase binding(GO:0017160)
0.1 1.7 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.1 0.8 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 3.5 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.1 0.4 GO:0016595 glutamate binding(GO:0016595)
0.1 0.6 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 1.6 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.1 2.3 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 0.9 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 2.4 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 1.6 GO:0005272 sodium channel activity(GO:0005272)
0.1 1.4 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 1.2 GO:0005123 death receptor binding(GO:0005123)
0.1 1.1 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.1 4.2 GO:0008013 beta-catenin binding(GO:0008013)
0.1 1.8 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 1.7 GO:0030515 snoRNA binding(GO:0030515)
0.1 27.2 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.1 0.9 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.1 0.8 GO:0035497 cAMP response element binding(GO:0035497)
0.1 1.2 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 0.6 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
0.1 2.4 GO:0005267 potassium channel activity(GO:0005267)
0.1 1.6 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.4 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.0 0.8 GO:0030332 cyclin binding(GO:0030332)
0.0 47.5 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.7 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.1 GO:0005113 patched binding(GO:0005113)
0.0 0.1 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 1.3 GO:0015179 L-amino acid transmembrane transporter activity(GO:0015179)
0.0 0.8 GO:0032947 protein complex scaffold(GO:0032947)
0.0 0.2 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 1.3 GO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191)
0.0 0.3 GO:0004890 GABA-A receptor activity(GO:0004890)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
5.2 134.4 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
3.0 66.9 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
2.8 147.1 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
1.6 37.3 ST ADRENERGIC Adrenergic Pathway
1.5 19.2 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
1.4 7.1 PID CERAMIDE PATHWAY Ceramide signaling pathway
1.3 5.4 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
1.2 20.9 ST G ALPHA I PATHWAY G alpha i Pathway
1.2 10.5 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
1.1 32.1 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
1.0 42.8 NABA PROTEOGLYCANS Genes encoding proteoglycans
1.0 23.8 PID NETRIN PATHWAY Netrin-mediated signaling events
1.0 2.0 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
1.0 25.4 PID CONE PATHWAY Visual signal transduction: Cones
1.0 16.6 PID IGF1 PATHWAY IGF1 pathway
1.0 20.4 PID NCADHERIN PATHWAY N-cadherin signaling events
1.0 9.6 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
1.0 20.1 PID S1P S1P1 PATHWAY S1P1 pathway
0.9 14.8 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.9 36.8 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.9 49.2 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.9 10.7 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.9 30.8 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.8 20.7 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.7 9.9 PID ALK2 PATHWAY ALK2 signaling events
0.6 28.7 PID CDC42 PATHWAY CDC42 signaling events
0.6 11.0 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.6 14.3 PID FAS PATHWAY FAS (CD95) signaling pathway
0.6 9.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.5 19.5 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.5 22.2 PID LKB1 PATHWAY LKB1 signaling events
0.5 4.2 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.5 6.4 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.4 87.2 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.4 4.1 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.4 7.0 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.4 19.1 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.3 2.3 PID BARD1 PATHWAY BARD1 signaling events
0.3 4.5 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.3 6.5 PID WNT SIGNALING PATHWAY Wnt signaling network
0.2 0.8 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.2 4.0 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.2 3.0 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.2 1.3 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.1 2.7 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.1 4.6 NABA CORE MATRISOME Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans
0.1 1.7 PID INSULIN PATHWAY Insulin Pathway
0.1 3.4 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.1 3.3 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.1 0.6 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.4 PID ARF 3PATHWAY Arf1 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
8.6 155.1 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
8.0 71.9 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
3.6 61.6 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
3.3 19.6 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
3.0 60.0 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
3.0 65.5 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
2.8 50.7 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
2.8 78.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
2.7 35.2 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
2.6 49.3 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
2.5 22.4 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
2.4 29.3 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
2.4 38.6 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
2.3 31.5 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
2.2 6.7 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
2.1 39.6 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
2.1 37.0 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
2.0 30.2 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
2.0 22.1 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
2.0 19.9 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
1.9 41.1 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
1.8 30.5 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
1.8 28.4 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
1.6 25.7 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
1.6 23.7 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
1.6 44.2 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
1.6 26.7 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
1.5 20.1 REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS Genes involved in Post NMDA receptor activation events
1.5 50.5 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
1.5 47.0 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
1.4 22.8 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
1.4 40.8 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
1.4 31.4 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
1.3 66.2 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
1.3 11.4 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
1.3 17.6 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
1.2 19.6 REACTOME GAP JUNCTION TRAFFICKING Genes involved in Gap junction trafficking
1.0 23.5 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
1.0 16.1 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
1.0 17.3 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.9 166.2 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.9 11.7 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.9 23.5 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.9 9.5 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.9 68.8 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.9 25.6 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.8 13.5 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.8 9.7 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.8 6.4 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.7 13.3 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.7 20.5 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.7 11.5 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.7 18.3 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.7 11.8 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.7 23.9 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.7 8.7 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.6 8.6 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.6 26.8 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.6 25.4 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.6 2.4 REACTOME ADP SIGNALLING THROUGH P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.6 12.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.5 6.5 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.5 15.6 REACTOME KINESINS Genes involved in Kinesins
0.5 7.1 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.5 8.0 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.5 4.8 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.5 6.6 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.5 13.1 REACTOME REGULATION OF INSULIN SECRETION Genes involved in Regulation of Insulin Secretion
0.5 1.9 REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.4 17.3 REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES Genes involved in Transmission across Chemical Synapses
0.4 4.2 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.4 3.6 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.4 10.7 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.4 19.7 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.4 9.6 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.3 12.0 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.3 2.8 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.3 11.3 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.3 7.5 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.2 3.7 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.2 2.2 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.2 4.7 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.2 4.1 REACTOME TRNA AMINOACYLATION Genes involved in tRNA Aminoacylation
0.2 14.8 REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE Genes involved in NGF signalling via TRKA from the plasma membrane
0.2 2.7 REACTOME ACYL CHAIN REMODELLING OF PC Genes involved in Acyl chain remodelling of PC
0.2 4.4 REACTOME MYOGENESIS Genes involved in Myogenesis
0.2 0.9 REACTOME SIGNALING BY FGFR Genes involved in Signaling by FGFR
0.1 2.9 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 1.4 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.1 5.7 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 0.7 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.1 1.4 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 1.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.3 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription