Project

GSE53960: rat RNA-Seq transcriptomic Bodymap

Navigation
Downloads

Results for Fosl2_Bach2

Z-value: 1.42

Motif logo

Transcription factors associated with Fosl2_Bach2

Gene Symbol Gene ID Gene Info
ENSRNOG00000052357 FOS like 2, AP-1 transcription factor subunit
ENSRNOG00000006170 BTB domain and CNC homolog 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Fosl2rn6_v1_chr6_-_25616995_256169950.652.8e-40Click!
Bach2rn6_v1_chr5_+_47546014_47546014-0.572.4e-29Click!

Activity profile of Fosl2_Bach2 motif

Sorted Z-values of Fosl2_Bach2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_9777465 79.64 ENSRNOT00000017413
NDRG family member 4
chr1_-_198232344 72.77 ENSRNOT00000080988
aldolase, fructose-bisphosphate A
chr7_+_59200918 64.67 ENSRNOT00000085073
protein tyrosine phosphatase, receptor type, R
chr3_+_152552822 62.09 ENSRNOT00000089719
erythrocyte membrane protein band 4.1-like 1
chr1_+_105284753 61.54 ENSRNOT00000041950
solute carrier family 6 member 5
chrX_-_142248369 60.73 ENSRNOT00000091330
fibroblast growth factor 13
chr9_+_38297322 44.89 ENSRNOT00000078157
ENSRNOT00000088824
BEN domain containing 6
chr13_-_73819896 41.52 ENSRNOT00000036392
family with sequence similarity 163, member A
chr16_-_81880502 41.51 ENSRNOT00000079096
MCF.2 cell line derived transforming sequence-like
chr1_-_42587666 41.40 ENSRNOT00000083225
ENSRNOT00000025355
regulator of G-protein signaling 17
chr7_+_3355116 39.61 ENSRNOT00000030453
ENSRNOT00000061657
integrin subunit alpha 7
chr20_+_5008508 38.75 ENSRNOT00000001153
von Willebrand factor A domain containing 7
chr17_+_13670520 37.74 ENSRNOT00000019442
SHC adaptor protein 3
chr10_-_82229140 36.91 ENSRNOT00000004400
epsin 3
chr16_-_10941414 36.49 ENSRNOT00000086627
ENSRNOT00000085414
ENSRNOT00000081631
ENSRNOT00000087521
ENSRNOT00000083623
LIM domain binding 3
chr15_-_77736892 35.75 ENSRNOT00000057924
protocadherin 9
chr1_-_100671074 35.35 ENSRNOT00000027132
myosin heavy chain 14
chr10_-_104575890 35.30 ENSRNOT00000050223
H3 histone family member 3B
chr9_-_19613360 34.35 ENSRNOT00000029593
regulator of calcineurin 2
chr13_+_89826254 33.40 ENSRNOT00000006141
F11 receptor
chr1_+_220335254 32.99 ENSRNOT00000072261
Ras and Rab interactor 1
chr5_+_164796185 32.60 ENSRNOT00000010779
natriuretic peptide B
chr1_+_89008117 30.83 ENSRNOT00000028401
heat shock protein family B (small) member 6
chrX_-_31968152 30.74 ENSRNOT00000004884
pirin
chr2_+_144861455 30.56 ENSRNOT00000093284
ENSRNOT00000019748
ENSRNOT00000072110
doublecortin-like kinase 1
chr1_+_79989019 30.44 ENSRNOT00000020428
dystrophia myotonica-protein kinase
chrX_+_17171605 30.43 ENSRNOT00000048236
nudix (nucleoside diphosphate linked moiety X)-type motif 10
chr4_-_157294047 30.01 ENSRNOT00000005601
enolase 2
chr1_+_20332371 29.85 ENSRNOT00000037259
transmembrane protein 200A
chr6_+_50528823 28.74 ENSRNOT00000008321
laminin subunit beta 1
chr1_+_220428481 28.69 ENSRNOT00000027335
ras and Rab interactor 1
chr9_+_20251521 28.59 ENSRNOT00000005535
gamma-enolase-like
chr3_+_124515978 28.58 ENSRNOT00000028881
prion protein
chr9_+_118586179 27.92 ENSRNOT00000022351
DLG associated protein 1
chr2_-_227207584 27.20 ENSRNOT00000065361
ENSRNOT00000080215
myozenin 2
chr8_-_59226597 25.82 ENSRNOT00000088208
acyl-CoA synthetase bubblegum family member 1
chr2_+_225310624 25.03 ENSRNOT00000015836
coagulation factor III, tissue factor
chr4_-_155690869 24.77 ENSRNOT00000012216
complement C3a receptor 1
chr10_-_51669297 23.74 ENSRNOT00000071595
Rho GTPase activating protein 44
chr10_+_55712043 23.41 ENSRNOT00000010141
arachidonate lipoxygenase 3
chr3_-_105512939 23.03 ENSRNOT00000011773
actin, alpha, cardiac muscle 1
chr10_-_56624526 22.21 ENSRNOT00000024973
acyl-CoA dehydrogenase, very long chain
chr2_+_240495371 22.05 ENSRNOT00000031425
solute carrier family 9 member B2
chr12_-_2568382 21.99 ENSRNOT00000035142
leucine rich repeat containing 8 family, member E
chr10_+_46018659 21.62 ENSRNOT00000040865
ENSRNOT00000004357
myosin phosphatase Rho interacting protein
chr4_-_62860446 21.42 ENSRNOT00000015752
family with sequence similarity 180, member A
chr8_+_55178289 21.16 ENSRNOT00000059127
crystallin, alpha B
chr15_-_61564695 20.96 ENSRNOT00000068216
regulator of cell cycle
chr16_+_23317953 20.68 ENSRNOT00000075287

chr20_+_25990656 20.45 ENSRNOT00000081254
leucine rich repeat transmembrane neuronal 3
chr9_-_49950093 20.09 ENSRNOT00000023014
four and a half LIM domains 2
chr2_-_45518502 19.78 ENSRNOT00000014627
heat shock protein family B (small) member 3
chr17_-_87826421 19.73 ENSRNOT00000068156
Rho GTPase activating protein 21
chr8_-_94368834 19.51 ENSRNOT00000078977
malic enzyme 1
chr10_-_85084850 19.07 ENSRNOT00000012462
TBK1 binding protein 1
chr1_-_31122093 18.96 ENSRNOT00000016712
SOGA family member 3
chr13_+_100980574 18.81 ENSRNOT00000067005
ENSRNOT00000004649
calpain 8
chr1_+_199941161 18.29 ENSRNOT00000027616
Bcl2-associated athanogene 3
chr5_+_169181418 18.24 ENSRNOT00000004508
kelch-like family member 21
chr20_+_25990304 18.19 ENSRNOT00000033980
leucine rich repeat transmembrane neuronal 3
chr6_+_42092467 18.03 ENSRNOT00000060499
E2F transcription factor 6
chr17_-_84488480 17.80 ENSRNOT00000000158
ENSRNOT00000075983
nebulette
chr13_-_88061108 17.63 ENSRNOT00000003774
regulator of G-protein signaling 4
chr1_+_84293102 17.23 ENSRNOT00000028468
SERTA domain containing 1
chr1_-_170318935 17.20 ENSRNOT00000024119
protein kinase C, delta binding protein
chr13_-_100928811 17.03 ENSRNOT00000045326
calpain 2
chr20_+_12658065 16.48 ENSRNOT00000072951
ENSRNOT00000001679
collagen type VI alpha 1 chain
chr10_-_71382058 16.37 ENSRNOT00000043148
dual specificity phosphatase 14
chr8_+_65611570 15.62 ENSRNOT00000017147
La ribonucleoprotein domain family, member 6
chr12_+_48292273 15.62 ENSRNOT00000000874
SV2 related protein
chrX_-_15627235 15.59 ENSRNOT00000013369
WD repeat domain 45
chr2_-_149417212 15.30 ENSRNOT00000018573
G protein-coupled receptor 87
chr2_-_187863503 14.96 ENSRNOT00000093036
ENSRNOT00000026705
ENSRNOT00000082174
lamin A/C
chr2_-_53811134 14.78 ENSRNOT00000020925
F-box protein 4
chr3_-_29984201 14.50 ENSRNOT00000006350
zinc finger E-box binding homeobox 2
chr7_-_124041594 14.35 ENSRNOT00000064700
cytochrome b5 reductase 3
chr1_-_89560469 14.27 ENSRNOT00000079091
sodium voltage-gated channel beta subunit 1
chr3_-_10602672 14.26 ENSRNOT00000011648
neuronal calcium sensor 1
chr2_-_26135340 14.18 ENSRNOT00000074626
coagulation factor II (thrombin) receptor
chr10_-_34333305 14.05 ENSRNOT00000071365
olfactory receptor gene Olr1384
chr1_+_114258719 13.86 ENSRNOT00000088459
ENSRNOT00000016376
cytoplasmic FMR1 interacting protein 1
chr18_+_56364620 13.69 ENSRNOT00000068535
ENSRNOT00000086033
platelet derived growth factor receptor beta
chr14_-_10395047 13.63 ENSRNOT00000002936
glycerol-3-phosphate acyltransferase 3
chr15_-_44860604 13.58 ENSRNOT00000018637
neurofilament medium
chr4_+_44573264 13.47 ENSRNOT00000080271
caveolin 2
chr4_+_118655728 13.37 ENSRNOT00000043082
AP2 associated kinase 1
chr4_-_39102807 13.11 ENSRNOT00000052063
thrombospondin type 1 domain containing 7A
chr7_-_93280009 13.08 ENSRNOT00000064877
sterile alpha motif domain containing 12
chrX_+_69730242 13.03 ENSRNOT00000075980
ENSRNOT00000076425
ectodysplasin-A
chr14_+_104250617 12.96 ENSRNOT00000079874
sprouty-related, EVH1 domain containing 2
chr7_-_11353713 12.92 ENSRNOT00000061132
zinc finger RNA binding protein 2
chr20_-_25826658 12.73 ENSRNOT00000057950
ENSRNOT00000084660
catenin alpha 3
chr20_+_3556975 12.68 ENSRNOT00000089417
discoidin domain receptor tyrosine kinase 1
chr3_-_149905944 12.68 ENSRNOT00000021715
syntrophin, alpha 1
chr8_-_49038169 12.55 ENSRNOT00000047303
pleckstrin homology-like domain, family B, member 1
chr12_-_17519954 12.42 ENSRNOT00000089418
Sad1 and UNC84 domain containing 1
chr10_+_91187593 12.41 ENSRNOT00000004163
acyl-CoA binding domain containing 4
chr4_-_98305173 12.30 ENSRNOT00000010151
interleukin 23 receptor
chr5_+_120340646 12.15 ENSRNOT00000086259
ENSRNOT00000086539
DnaJ heat shock protein family (Hsp40) member C6
chr13_+_89480058 12.09 ENSRNOT00000050804
cilia and flagella associated protein 126
chr2_+_22909569 12.09 ENSRNOT00000073871
homer scaffolding protein 1
chr2_-_186480278 12.08 ENSRNOT00000031743
kin of IRRE like (Drosophila)
chr2_-_28799266 12.05 ENSRNOT00000089293
transmembrane protein 171
chr3_-_164055561 11.89 ENSRNOT00000064849
beta-1,4-galactosyltransferase 5
chrX_+_43625169 11.87 ENSRNOT00000086311
spermidine/spermine N1-acetyl transferase 1
chrM_+_7919 11.86 ENSRNOT00000046108
mitochondrially encoded ATP synthase 6
chr8_+_69971778 11.86 ENSRNOT00000058007
ENSRNOT00000037941
ENSRNOT00000050649
multiple EGF-like-domains 11
chr14_+_89314176 11.58 ENSRNOT00000006765
uridine phosphorylase 1
chr13_+_87986240 11.58 ENSRNOT00000003705
regulator of G-protein signaling 5
chr2_-_187854363 11.35 ENSRNOT00000092993
lamin A/C
chr18_+_15467870 11.11 ENSRNOT00000091696
beta-1,4-galactosyltransferase 6
chr2_-_171196395 10.91 ENSRNOT00000013279
butyrylcholinesterase
chr10_+_104582955 10.66 ENSRNOT00000009733
unkempt family zinc finger
chr3_-_15433252 10.66 ENSRNOT00000008817
LIM homeobox 6
chr9_-_27447877 10.49 ENSRNOT00000085195
glutathione S-transferase alpha 1
chr8_-_128249538 10.43 ENSRNOT00000082892
sodium voltage-gated channel alpha subunit 5
chr10_+_15672382 10.38 ENSRNOT00000027965
rhomboid 5 homolog 1
chr1_+_25174456 10.16 ENSRNOT00000092830
clavesin 2
chr17_+_10537365 10.12 ENSRNOT00000023651
clathrin, light chain B
chr2_-_200003443 10.10 ENSRNOT00000024900
ENSRNOT00000088041
phosphodiesterase 4D interacting protein
chr18_+_81821127 10.07 ENSRNOT00000058199
F-box protein 15
chr11_+_87435185 10.02 ENSRNOT00000002558
purinergic receptor P2X 6
chr1_+_212359177 9.99 ENSRNOT00000046314
zinc finger protein 511
chr4_-_145454834 9.97 ENSRNOT00000013154
ENSRNOT00000056493
proline-rich transmembrane protein 3
chr4_+_33638709 9.93 ENSRNOT00000009888
ENSRNOT00000034719
ENSRNOT00000052333
tachykinin, precursor 1
chr2_+_187322416 9.77 ENSRNOT00000025183
cellular retinoic acid binding protein 2
chr17_-_35037076 9.61 ENSRNOT00000090946
dual specificity phosphatase 22
chrM_+_7758 9.57 ENSRNOT00000046201
mitochondrially encoded ATP synthase 8
chr1_-_101514547 9.55 ENSRNOT00000079633
protein phosphatase 1, regulatory subunit 15A
chr12_+_48598647 9.48 ENSRNOT00000000889
transmembrane protein 119
chr7_-_72328128 9.48 ENSRNOT00000008227
TSPY-like 5
chr18_-_6782757 9.18 ENSRNOT00000068150
aquaporin 4
chr9_-_37231291 9.17 ENSRNOT00000016237
protein tyrosine phosphatase type IVA, member 1
chr14_+_34727915 9.17 ENSRNOT00000085089
kinase insert domain receptor
chr1_+_220826560 9.12 ENSRNOT00000027891
FOS like 1, AP-1 transcription factor subunit
chr8_+_5676665 9.07 ENSRNOT00000012310
matrix metallopeptidase 3
chr8_-_104593625 8.93 ENSRNOT00000016625
zinc finger and BTB domain containing 38
chr13_+_84474319 8.92 ENSRNOT00000031367
ENSRNOT00000072244
ENSRNOT00000072897
ENSRNOT00000064168
ENSRNOT00000074954
ENSRNOT00000073696
immunoglobulin-like domain containing receptor 2
chr1_-_87191588 8.83 ENSRNOT00000027998
rCG54286-like
chr4_+_168615890 8.75 ENSRNOT00000009324
cAMP responsive element binding protein-like 2
chr11_+_46179940 8.62 ENSRNOT00000088152
Trk-fused gene
chr7_+_70580198 8.54 ENSRNOT00000083472
ENSRNOT00000008941
DNA-damage inducible transcript 3
chr14_+_34727623 8.50 ENSRNOT00000071405
ENSRNOT00000090183
kinase insert domain receptor
chrX_+_65566047 8.41 ENSRNOT00000092103
hephaestin
chr2_-_197860699 8.32 ENSRNOT00000028740
extracellular matrix protein 1
chr5_+_28395296 8.29 ENSRNOT00000009375
transmembrane protein 55A
chr9_+_20951260 8.28 ENSRNOT00000016906
adhesion G protein-coupled receptor F4
chr10_+_35857797 8.23 ENSRNOT00000004517
chibby family member 3
chr8_+_65733400 8.23 ENSRNOT00000089126
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr17_+_9109731 8.16 ENSRNOT00000016009
C-X-C motif chemokine ligand 14
chr18_+_27923572 8.16 ENSRNOT00000008041
catenin alpha 1
chr8_+_119228612 8.14 ENSRNOT00000078439
ENSRNOT00000043737
leucine rich repeat containing 2
chr5_+_140870140 8.12 ENSRNOT00000074347
hippocalcin-like 4
chr18_-_27749235 8.04 ENSRNOT00000026696
heat shock protein family A member 9
chr7_+_144647587 7.89 ENSRNOT00000022398
homeo box C4
chr9_+_82436458 7.85 ENSRNOT00000026467
ENSRNOT00000081958
DnaJ heat shock protein family (Hsp40) member B2
chr19_+_41968705 7.83 ENSRNOT00000020365
IST1, ESCRT-III associated factor
chr14_+_23166633 7.66 ENSRNOT00000060109
transmembrane protease, serine 11G
chr13_-_95348913 7.58 ENSRNOT00000057879
AKT serine/threonine kinase 3
chr2_-_178297172 7.57 ENSRNOT00000038543
folliculin interacting protein 2
chr6_+_64224861 7.46 ENSRNOT00000093159
ENSRNOT00000093664
patatin-like phospholipase domain containing 8
chr15_+_28295368 7.43 ENSRNOT00000013786
solute carrier family 39 member 2
chr2_+_211337271 7.34 ENSRNOT00000045155
cytochrome c oxidase subunit 6B1
chr1_+_238843338 7.33 ENSRNOT00000024583
zinc finger AN1-type containing 5
chr3_-_29993715 7.28 ENSRNOT00000085801
zinc finger E-box binding homeobox 2
chr7_+_121480723 7.24 ENSRNOT00000065304
activating transcription factor 4
chr5_+_143027977 7.18 ENSRNOT00000012702
G protein nucleolar 2
chr5_+_156613741 7.12 ENSRNOT00000076031
SH2 domain containing 5
chr3_-_81911197 7.09 ENSRNOT00000066526
PR/SET domain 11
chr6_+_135610743 7.04 ENSRNOT00000010906
Tnf receptor-associated factor 3
chr1_-_222734184 6.97 ENSRNOT00000049812
ENSRNOT00000028785
reticulon 3
chr2_+_46980976 6.94 ENSRNOT00000083668
ENSRNOT00000082990
molybdenum cofactor synthesis 2
chr4_-_166869399 6.93 ENSRNOT00000007521
taste receptor, type 2, member 121
chr19_+_41631715 6.92 ENSRNOT00000022749
carbohydrate sulfotransferase 4
chr9_+_27402381 6.88 ENSRNOT00000077372
glutathione S-transferase alpha 3
chr6_+_92057807 6.84 ENSRNOT00000006509
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B)
chr17_-_10208360 6.78 ENSRNOT00000087397
unc-5 netrin receptor A
chr1_+_89215266 6.72 ENSRNOT00000093612
ENSRNOT00000084799
dermokine
chr2_-_113345577 6.72 ENSRNOT00000034096
fibronectin type III domain containing 3B
chr6_+_136330383 6.66 ENSRNOT00000093106
ENSRNOT00000092774
ENSRNOT00000065281
ENSRNOT00000015935
kinesin light chain 1
chr8_-_39551700 6.63 ENSRNOT00000091894
ENSRNOT00000076025
PBX/knotted 1 homeobox 2
chr2_+_203200427 6.60 ENSRNOT00000020566
V-set domain containing T cell activation inhibitor 1
chr11_+_68198709 6.53 ENSRNOT00000003048
disrupted in renal carcinoma 2
chr6_-_71199110 6.52 ENSRNOT00000081883
protein kinase D1
chr4_+_97657671 6.51 ENSRNOT00000075400
G protein subunit gamma 12
chrX_+_18489597 6.51 ENSRNOT00000059744
similar to potassium channel tetramerisation domain containing 12b
chrX_-_15587419 6.46 ENSRNOT00000012829
transcription factor binding to IGHM enhancer 3
chr14_-_22009300 6.45 ENSRNOT00000088491
ENSRNOT00000087923
casein alpha s1
chr9_+_62291405 6.39 ENSRNOT00000051463
phospholipase C-like 1
chrX_+_111798233 6.36 ENSRNOT00000078582
phosphoribosyl pyrophosphate synthetase 1
chr3_+_48082935 6.35 ENSRNOT00000087711
ENSRNOT00000067545
solute carrier family 4 member 10
chr1_+_218466289 6.33 ENSRNOT00000017948
MAS related GPR family member F
chr3_+_2648885 6.24 ENSRNOT00000020339
ATP binding cassette subfamily A member 2
chr5_-_141242131 6.09 ENSRNOT00000081482
microtubule-actin crosslinking factor 1
chr16_-_14382641 5.99 ENSRNOT00000018723
growth hormone inducible transmembrane protein
chr1_-_169040725 5.97 ENSRNOT00000046616
olfactory receptor 130
chr3_-_71893600 5.97 ENSRNOT00000006787
ENSRNOT00000057685
tissue factor pathway inhibitor
chr2_-_33025271 5.84 ENSRNOT00000074941
microtubule associated serine/threonine kinase family member 4
chr3_-_92242318 5.81 ENSRNOT00000007018
tripartite motif-containing 44
chr11_-_84047497 5.73 ENSRNOT00000088821
ENSRNOT00000058092
adaptor-related protein complex 2, mu 1 subunit

Network of associatons between targets according to the STRING database.

First level regulatory network of Fosl2_Bach2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
16.2 64.7 GO:0038128 ERBB2 signaling pathway(GO:0038128)
12.3 61.5 GO:0036233 glycine import(GO:0036233)
9.6 28.7 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
9.0 27.1 GO:1904178 sterol regulatory element binding protein import into nucleus(GO:0035105) negative regulation of adipose tissue development(GO:1904178)
8.8 79.6 GO:2001135 regulation of endocytic recycling(GO:2001135)
8.7 60.7 GO:0045196 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
8.3 25.0 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
8.3 24.8 GO:0002462 tolerance induction to nonself antigen(GO:0002462)
7.6 30.3 GO:1901911 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
7.3 21.8 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
7.1 35.3 GO:0031508 pericentric heterochromatin assembly(GO:0031508) regulation of chromosome condensation(GO:0060623)
7.0 21.0 GO:0003330 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
6.8 13.6 GO:0033693 neurofilament bundle assembly(GO:0033693)
6.5 58.6 GO:0061718 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
6.1 30.4 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
6.1 72.8 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
5.9 23.7 GO:0098886 modification of dendritic spine(GO:0098886)
5.9 17.8 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
5.8 23.0 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
5.5 22.1 GO:2001206 positive regulation of osteoclast development(GO:2001206)
5.2 25.8 GO:0001552 ovarian follicle atresia(GO:0001552)
5.1 15.4 GO:0030473 nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration(GO:0021817) nuclear migration along microtubule(GO:0030473) nuclear matrix anchoring at nuclear membrane(GO:0090292)
4.9 19.7 GO:0051684 maintenance of Golgi location(GO:0051684)
4.8 28.6 GO:1900272 negative regulation of calcineurin-NFAT signaling cascade(GO:0070885) negative regulation of long-term synaptic potentiation(GO:1900272) negative regulation of dendritic spine maintenance(GO:1902951)
4.7 9.5 GO:1903012 positive regulation of bone development(GO:1903012)
4.7 14.2 GO:0099553 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
4.7 23.4 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
4.7 32.6 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
4.6 13.9 GO:1903422 negative regulation of synaptic vesicle recycling(GO:1903422)
4.6 13.7 GO:0038091 VEGF-activated platelet-derived growth factor receptor signaling pathway(GO:0038086) positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway(GO:0038091)
4.5 13.5 GO:0019065 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
4.3 13.0 GO:0061152 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
4.1 24.7 GO:0086047 membrane depolarization during Purkinje myocyte cell action potential(GO:0086047)
3.6 10.9 GO:0014016 neuroblast differentiation(GO:0014016)
3.6 7.2 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
3.5 27.9 GO:0070842 aggresome assembly(GO:0070842)
3.5 41.8 GO:1902993 positive regulation of beta-amyloid formation(GO:1902004) positive regulation of amyloid precursor protein catabolic process(GO:1902993)
3.5 24.2 GO:0038033 positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway(GO:0038033)
3.2 9.5 GO:0072703 regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734) response to methyl methanesulfonate(GO:0072702) cellular response to methyl methanesulfonate(GO:0072703) response to environmental enrichment(GO:0090648) positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
3.0 33.0 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
3.0 11.9 GO:0032919 spermine acetylation(GO:0032919)
2.9 11.5 GO:0072318 clathrin coat disassembly(GO:0072318)
2.8 22.2 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
2.7 8.2 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
2.7 21.6 GO:0035509 negative regulation of myosin-light-chain-phosphatase activity(GO:0035509)
2.7 8.0 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
2.6 15.8 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
2.6 7.9 GO:1990790 response to glial cell derived neurotrophic factor(GO:1990790) cellular response to glial cell derived neurotrophic factor(GO:1990792)
2.6 7.7 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
2.5 34.4 GO:0007614 short-term memory(GO:0007614)
2.3 9.2 GO:0060354 negative regulation of cell adhesion molecule production(GO:0060354)
2.3 6.9 GO:0046223 toxin catabolic process(GO:0009407) mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) secondary metabolite catabolic process(GO:0090487) organic heteropentacyclic compound catabolic process(GO:1901377)
2.3 9.1 GO:0007296 vitellogenesis(GO:0007296)
2.1 6.4 GO:0034418 urate biosynthetic process(GO:0034418)
2.1 17.0 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
2.1 21.2 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
2.1 6.2 GO:0032380 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
2.0 62.1 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
2.0 9.9 GO:2000851 positive regulation of saliva secretion(GO:0046878) positive regulation of glucocorticoid secretion(GO:2000851)
2.0 3.9 GO:1900186 negative regulation of clathrin-mediated endocytosis(GO:1900186)
2.0 19.5 GO:1902031 regulation of NADP metabolic process(GO:1902031)
1.9 11.6 GO:0010138 pyrimidine ribonucleotide salvage(GO:0010138) pyrimidine nucleotide salvage(GO:0032262) UMP salvage(GO:0044206)
1.9 35.8 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
1.9 7.5 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
1.8 12.7 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
1.7 6.9 GO:0042339 keratan sulfate metabolic process(GO:0042339)
1.7 8.5 GO:0071500 cellular response to nitrosative stress(GO:0071500)
1.6 12.7 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
1.6 4.7 GO:0061741 vacuolar transmembrane transport(GO:0034486) chaperone-mediated protein transport involved in chaperone-mediated autophagy(GO:0061741) negative regulation of complement-dependent cytotoxicity(GO:1903660)
1.5 13.6 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
1.4 20.1 GO:0055015 ventricular cardiac muscle cell development(GO:0055015)
1.4 2.9 GO:0051695 actin filament uncapping(GO:0051695)
1.4 41.4 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
1.4 15.7 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
1.4 5.7 GO:0051692 cellular oligosaccharide catabolic process(GO:0051692)
1.4 40.9 GO:0071625 vocalization behavior(GO:0071625)
1.4 15.3 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
1.4 4.1 GO:1901526 positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
1.4 8.2 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
1.4 44.9 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
1.3 6.7 GO:0035617 stress granule disassembly(GO:0035617)
1.3 4.0 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
1.3 10.5 GO:0043651 linoleic acid metabolic process(GO:0043651)
1.3 2.6 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
1.3 3.9 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
1.3 45.9 GO:0010664 negative regulation of striated muscle cell apoptotic process(GO:0010664)
1.3 3.8 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
1.2 65.4 GO:0030239 myofibril assembly(GO:0030239)
1.2 17.0 GO:0016540 protein autoprocessing(GO:0016540)
1.2 3.6 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
1.2 10.7 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
1.1 6.8 GO:0033564 anterior/posterior axon guidance(GO:0033564)
1.1 29.3 GO:0000188 inactivation of MAPK activity(GO:0000188)
1.1 7.8 GO:0009838 abscission(GO:0009838)
1.1 3.4 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
1.1 19.6 GO:0048875 chemical homeostasis within a tissue(GO:0048875)
1.1 4.3 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
1.1 10.7 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
1.0 9.1 GO:0010727 negative regulation of hydrogen peroxide metabolic process(GO:0010727)
1.0 14.1 GO:0002138 retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102)
1.0 5.0 GO:0009115 xanthine catabolic process(GO:0009115)
1.0 4.0 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
1.0 7.0 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
1.0 7.8 GO:0090086 negative regulation of protein deubiquitination(GO:0090086)
1.0 12.5 GO:2001197 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.9 6.6 GO:0072602 interleukin-4 secretion(GO:0072602)
0.9 30.6 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.9 1.8 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.9 7.0 GO:0008063 Toll signaling pathway(GO:0008063)
0.8 6.7 GO:0060510 Type II pneumocyte differentiation(GO:0060510)
0.8 30.7 GO:0030224 monocyte differentiation(GO:0030224)
0.8 3.8 GO:0019563 glycerol catabolic process(GO:0019563)
0.8 6.1 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.7 16.5 GO:0070208 protein heterotrimerization(GO:0070208)
0.7 11.1 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
0.7 21.4 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.7 5.0 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.7 8.4 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.7 29.2 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.7 5.4 GO:1901524 regulation of macromitophagy(GO:1901524) negative regulation of macromitophagy(GO:1901525)
0.7 2.7 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.7 17.0 GO:0010842 retina layer formation(GO:0010842)
0.6 9.6 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.6 0.6 GO:0038089 positive regulation of cell migration by vascular endothelial growth factor signaling pathway(GO:0038089)
0.6 6.9 GO:0006777 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.6 4.4 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.6 13.4 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.6 2.3 GO:0090625 siRNA loading onto RISC involved in RNA interference(GO:0035087) mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.6 17.7 GO:0034629 cellular protein complex localization(GO:0034629)
0.5 5.8 GO:0032060 bleb assembly(GO:0032060)
0.5 8.3 GO:0002827 positive regulation of T-helper 1 type immune response(GO:0002827)
0.5 3.6 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.5 2.4 GO:0009181 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.5 1.4 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.5 3.2 GO:0010529 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529) spongiotrophoblast cell proliferation(GO:0060720) cell proliferation involved in embryonic placenta development(GO:0060722)
0.4 7.6 GO:0045793 positive regulation of cell size(GO:0045793)
0.4 3.4 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.4 6.3 GO:0021860 pyramidal neuron development(GO:0021860)
0.4 8.4 GO:0006825 copper ion transport(GO:0006825)
0.4 4.3 GO:0034374 low-density lipoprotein particle remodeling(GO:0034374)
0.4 1.9 GO:0061635 regulation of protein complex stability(GO:0061635)
0.4 7.3 GO:0048745 smooth muscle tissue development(GO:0048745)
0.4 2.6 GO:0097210 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.4 35.2 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.4 4.4 GO:2000811 negative regulation of anoikis(GO:2000811)
0.4 14.3 GO:0006695 cholesterol biosynthetic process(GO:0006695)
0.3 5.2 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.3 3.4 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.3 1.6 GO:0000066 mitochondrial ornithine transport(GO:0000066)
0.3 0.3 GO:0003273 cell migration involved in endocardial cushion formation(GO:0003273)
0.3 6.4 GO:0032228 regulation of synaptic transmission, GABAergic(GO:0032228)
0.3 9.5 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.3 8.3 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.3 2.9 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.3 1.6 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.3 2.3 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.3 12.1 GO:0007588 excretion(GO:0007588)
0.2 6.9 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.2 42.4 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.2 5.4 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.2 2.3 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.2 2.4 GO:0050872 white fat cell differentiation(GO:0050872)
0.2 18.8 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.2 1.7 GO:0060717 chorion development(GO:0060717)
0.2 10.1 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.2 1.5 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.2 3.1 GO:0043248 proteasome assembly(GO:0043248)
0.2 2.5 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.2 10.2 GO:0007040 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.2 2.3 GO:0032825 positive regulation of natural killer cell differentiation(GO:0032825)
0.2 7.3 GO:0021762 substantia nigra development(GO:0021762)
0.2 6.5 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.2 4.7 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.2 8.3 GO:0001938 positive regulation of endothelial cell proliferation(GO:0001938)
0.2 11.3 GO:0045921 positive regulation of exocytosis(GO:0045921)
0.1 4.0 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.1 1.0 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.1 3.8 GO:0033344 cholesterol efflux(GO:0033344)
0.1 15.3 GO:0030308 negative regulation of cell growth(GO:0030308)
0.1 0.5 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.1 6.5 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.1 4.7 GO:0000266 mitochondrial fission(GO:0000266)
0.1 0.2 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
0.1 39.5 GO:0030900 forebrain development(GO:0030900)
0.1 11.8 GO:0007586 digestion(GO:0007586)
0.1 4.3 GO:0001578 microtubule bundle formation(GO:0001578)
0.1 3.4 GO:0045598 regulation of fat cell differentiation(GO:0045598)
0.1 3.2 GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631)
0.1 1.0 GO:0015747 urate transport(GO:0015747)
0.1 44.0 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.1 2.5 GO:0010107 potassium ion import(GO:0010107)
0.1 0.3 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 12.1 GO:0044782 cilium organization(GO:0044782)
0.1 11.7 GO:0009749 response to glucose(GO:0009749)
0.1 6.8 GO:0015992 proton transport(GO:0015992)
0.1 3.3 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.1 1.4 GO:0006301 postreplication repair(GO:0006301)
0.1 0.3 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1 0.2 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.3 GO:0061450 nail development(GO:0035878) trophoblast cell migration(GO:0061450)
0.0 1.7 GO:0051438 regulation of ubiquitin-protein transferase activity(GO:0051438)
0.0 0.9 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 49.4 GO:0007608 sensory perception of smell(GO:0007608)
0.0 0.3 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.0 2.0 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 0.2 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 2.9 GO:0007606 sensory perception of chemical stimulus(GO:0007606)
0.0 3.1 GO:0071804 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0 2.2 GO:0007018 microtubule-based movement(GO:0007018)
0.0 0.4 GO:0030204 chondroitin sulfate metabolic process(GO:0030204)
0.0 0.2 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
9.8 58.6 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
8.8 35.4 GO:0097513 myosin II filament(GO:0097513)
7.9 39.6 GO:0005927 muscle tendon junction(GO:0005927)
7.2 28.7 GO:0043259 laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259)
4.4 35.3 GO:0001740 Barr body(GO:0001740)
4.3 72.8 GO:0035686 sperm fibrous sheath(GO:0035686)
3.4 27.1 GO:0005638 lamin filament(GO:0005638)
3.3 33.4 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
2.8 8.5 GO:1990622 CHOP-C/EBP complex(GO:0036488) CHOP-ATF3 complex(GO:1990622)
2.6 18.2 GO:0005827 polar microtubule(GO:0005827)
2.4 7.2 GO:1990037 Lewy body core(GO:1990037) ATF4-CREB1 transcription factor complex(GO:1990589) ATF1-ATF4 transcription factor complex(GO:1990590)
2.4 21.2 GO:0097512 cardiac myofibril(GO:0097512)
2.2 17.7 GO:0097443 sorting endosome(GO:0097443)
2.0 14.2 GO:0031094 platelet dense tubular network(GO:0031094)
1.9 28.3 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
1.7 21.9 GO:0031143 pseudopodium(GO:0031143)
1.6 8.2 GO:0043293 apoptosome(GO:0043293)
1.5 13.9 GO:0031209 SCAR complex(GO:0031209)
1.5 16.7 GO:0097418 neurofibrillary tangle(GO:0097418)
1.3 25.5 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
1.3 13.4 GO:0071439 clathrin complex(GO:0071439)
1.3 24.7 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
1.3 3.8 GO:0098837 postsynaptic recycling endosome(GO:0098837)
1.3 6.4 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
1.2 156.7 GO:0031674 I band(GO:0031674)
1.1 18.2 GO:0031045 dense core granule(GO:0031045)
1.1 7.8 GO:0090543 Flemming body(GO:0090543)
1.1 10.9 GO:0005641 nuclear envelope lumen(GO:0005641)
1.1 30.4 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
1.1 6.3 GO:0097441 basilar dendrite(GO:0097441)
1.0 22.1 GO:0097228 sperm principal piece(GO:0097228)
0.9 84.0 GO:0044291 cell-cell contact zone(GO:0044291)
0.9 4.7 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.9 13.0 GO:0043202 lysosomal lumen(GO:0043202)
0.8 13.2 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.8 36.9 GO:0005905 clathrin-coated pit(GO:0005905)
0.8 12.5 GO:0045180 basal cortex(GO:0045180)
0.8 3.8 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.7 9.5 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.7 15.6 GO:0019013 viral nucleocapsid(GO:0019013)
0.7 13.0 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.6 29.8 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.6 7.0 GO:0035631 CD40 receptor complex(GO:0035631)
0.6 13.5 GO:0002080 acrosomal membrane(GO:0002080)
0.6 30.2 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.6 18.0 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.5 6.7 GO:0035253 ciliary rootlet(GO:0035253)
0.5 161.1 GO:0014069 postsynaptic density(GO:0014069)
0.5 54.7 GO:0045211 postsynaptic membrane(GO:0045211)
0.5 5.4 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.4 8.8 GO:0043034 costamere(GO:0043034)
0.4 9.2 GO:0005838 proteasome regulatory particle(GO:0005838)
0.4 2.3 GO:0032585 multivesicular body membrane(GO:0032585)
0.4 12.1 GO:0043198 dendritic shaft(GO:0043198)
0.3 42.5 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.3 5.6 GO:0060076 excitatory synapse(GO:0060076)
0.3 22.4 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.3 2.3 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.3 1.9 GO:0044754 autolysosome(GO:0044754)
0.3 2.9 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.3 0.3 GO:0097413 Lewy body(GO:0097413)
0.3 3.6 GO:0005796 Golgi lumen(GO:0005796)
0.3 9.2 GO:0046930 pore complex(GO:0046930)
0.3 4.1 GO:0045259 proton-transporting ATP synthase complex(GO:0045259)
0.3 64.7 GO:0031253 cell projection membrane(GO:0031253)
0.3 14.4 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.2 5.2 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.2 6.5 GO:0000421 autophagosome membrane(GO:0000421)
0.2 19.6 GO:0042383 sarcolemma(GO:0042383)
0.2 5.4 GO:0098827 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.2 10.7 GO:0005844 polysome(GO:0005844)
0.2 9.9 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.2 3.3 GO:0030131 clathrin adaptor complex(GO:0030131)
0.2 11.7 GO:0030016 myofibril(GO:0030016)
0.2 3.3 GO:0042588 zymogen granule(GO:0042588)
0.2 4.9 GO:0042734 presynaptic membrane(GO:0042734)
0.2 27.0 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.2 0.9 GO:0022624 proteasome accessory complex(GO:0022624)
0.2 2.4 GO:0035102 PRC1 complex(GO:0035102)
0.2 4.2 GO:0005771 multivesicular body(GO:0005771)
0.2 8.3 GO:0031902 late endosome membrane(GO:0031902)
0.1 6.6 GO:0045171 intercellular bridge(GO:0045171)
0.1 3.6 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.1 1.4 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.1 5.4 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 37.5 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.1 12.1 GO:0036064 ciliary basal body(GO:0036064)
0.1 4.7 GO:0030658 transport vesicle membrane(GO:0030658)
0.1 12.2 GO:0031227 intrinsic component of endoplasmic reticulum membrane(GO:0031227)
0.1 5.8 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 7.7 GO:0019898 extrinsic component of membrane(GO:0019898)
0.1 2.2 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 26.1 GO:0030425 dendrite(GO:0030425)
0.1 26.9 GO:0000139 Golgi membrane(GO:0000139)
0.1 25.6 GO:0016607 nuclear speck(GO:0016607)
0.1 2.3 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.1 5.0 GO:0005581 collagen trimer(GO:0005581)
0.1 6.7 GO:0010008 endosome membrane(GO:0010008)
0.1 4.5 GO:0030659 cytoplasmic vesicle membrane(GO:0030659)
0.1 3.8 GO:0016363 nuclear matrix(GO:0016363)
0.0 16.1 GO:0005813 centrosome(GO:0005813)
0.0 18.9 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 0.9 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.3 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 6.9 GO:0005794 Golgi apparatus(GO:0005794)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
20.5 61.5 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
10.4 72.8 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
9.8 58.6 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
8.6 34.4 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
7.6 30.3 GO:0008486 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
7.4 22.2 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
7.1 28.6 GO:1903135 cupric ion binding(GO:1903135)
6.5 19.5 GO:0008948 oxaloacetate decarboxylase activity(GO:0008948)
5.4 27.2 GO:0051373 FATZ binding(GO:0051373)
4.9 24.7 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
4.6 13.7 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
4.0 11.9 GO:0019809 spermidine binding(GO:0019809)
3.6 10.9 GO:0003990 acetylcholinesterase activity(GO:0003990)
3.6 14.3 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
3.5 17.7 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
3.5 14.1 GO:0015057 thrombin receptor activity(GO:0015057)
3.2 28.7 GO:0043208 glycosphingolipid binding(GO:0043208)
3.1 12.3 GO:0005143 interleukin-12 receptor binding(GO:0005143)
2.8 11.1 GO:0008489 UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity(GO:0008489)
2.6 25.8 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
2.6 36.0 GO:0030898 actin-dependent ATPase activity(GO:0030898)
2.5 10.1 GO:0032050 clathrin heavy chain binding(GO:0032050)
2.4 4.8 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
2.4 12.1 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
2.4 14.3 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
2.3 36.5 GO:0051371 muscle alpha-actinin binding(GO:0051371)
2.3 13.6 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
2.3 24.8 GO:0004875 complement receptor activity(GO:0004875)
2.2 15.7 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
2.1 27.9 GO:0098919 structural constituent of postsynaptic specialization(GO:0098879) structural constituent of postsynaptic density(GO:0098919)
2.1 8.3 GO:0005134 interleukin-2 receptor binding(GO:0005134)
2.0 22.1 GO:0015385 sodium:proton antiporter activity(GO:0015385)
2.0 17.7 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
1.9 54.1 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
1.9 42.2 GO:0005212 structural constituent of eye lens(GO:0005212)
1.9 13.0 GO:0005173 stem cell factor receptor binding(GO:0005173)
1.8 18.3 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
1.8 5.4 GO:0005135 erythropoietin receptor binding(GO:0005128) interleukin-3 receptor binding(GO:0005135)
1.8 10.7 GO:1990715 mRNA CDS binding(GO:1990715)
1.7 73.4 GO:0017080 sodium channel regulator activity(GO:0017080)
1.7 22.0 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
1.7 11.7 GO:0042030 ATPase inhibitor activity(GO:0042030)
1.7 41.5 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
1.7 8.3 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
1.6 4.7 GO:0002134 UTP binding(GO:0002134) sulfonylurea receptor binding(GO:0017098) pyrimidine ribonucleoside binding(GO:0032551)
1.5 36.2 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
1.5 16.5 GO:0048407 platelet-derived growth factor binding(GO:0048407)
1.5 16.1 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
1.4 5.7 GO:0052796 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
1.4 8.4 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
1.4 36.7 GO:0008157 protein phosphatase 1 binding(GO:0008157)
1.4 6.8 GO:0005042 netrin receptor activity(GO:0005042)
1.3 43.0 GO:0070412 R-SMAD binding(GO:0070412)
1.3 44.9 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
1.3 3.8 GO:0052591 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
1.3 15.3 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
1.2 15.8 GO:0043522 leucine zipper domain binding(GO:0043522)
1.2 6.9 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
1.1 19.4 GO:0005523 tropomyosin binding(GO:0005523)
1.1 10.0 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
1.1 4.4 GO:0033149 FFAT motif binding(GO:0033149)
1.1 25.8 GO:0051428 peptide hormone receptor binding(GO:0051428)
1.0 35.3 GO:0031492 nucleosomal DNA binding(GO:0031492)
1.0 13.5 GO:0031748 D1 dopamine receptor binding(GO:0031748)
1.0 13.4 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
1.0 16.4 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
1.0 4.0 GO:0032558 adenyl deoxyribonucleotide binding(GO:0032558)
1.0 5.0 GO:0004031 aldehyde oxidase activity(GO:0004031) xanthine dehydrogenase activity(GO:0004854) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623) oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor(GO:0016726)
0.9 7.5 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.9 37.4 GO:0001784 phosphotyrosine binding(GO:0001784)
0.9 15.4 GO:0005521 lamin binding(GO:0005521)
0.9 8.2 GO:0045295 gamma-catenin binding(GO:0045295)
0.9 3.6 GO:0005163 nerve growth factor receptor binding(GO:0005163)
0.9 93.1 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.9 2.6 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.8 5.8 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.8 9.8 GO:0019841 retinol binding(GO:0019841)
0.8 6.4 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.8 3.9 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.8 5.4 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.8 13.0 GO:0005123 death receptor binding(GO:0005123)
0.7 3.7 GO:0038132 neuregulin binding(GO:0038132)
0.7 3.6 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.7 13.0 GO:0043295 glutathione binding(GO:0043295)
0.7 9.2 GO:0015250 water channel activity(GO:0015250)
0.6 6.9 GO:0016783 sulfurtransferase activity(GO:0016783)
0.6 13.7 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.6 1.8 GO:0031766 galanin receptor binding(GO:0031763) type 2 galanin receptor binding(GO:0031765) type 3 galanin receptor binding(GO:0031766)
0.6 3.4 GO:0048030 disaccharide binding(GO:0048030)
0.6 3.4 GO:0045545 syndecan binding(GO:0045545)
0.5 150.3 GO:0005096 GTPase activator activity(GO:0005096)
0.5 37.4 GO:0017022 myosin binding(GO:0017022)
0.5 9.6 GO:0060590 ATPase activator activity(GO:0001671) ATPase regulator activity(GO:0060590)
0.5 30.4 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.5 1.5 GO:0003844 1,4-alpha-glucan branching enzyme activity(GO:0003844)
0.5 6.9 GO:0033038 bitter taste receptor activity(GO:0033038)
0.5 2.4 GO:0047631 adenosine-diphosphatase activity(GO:0043262) ADP-ribose diphosphatase activity(GO:0047631)
0.5 12.4 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.5 1.4 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.5 6.4 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.4 8.9 GO:0008327 methyl-CpG binding(GO:0008327)
0.4 1.8 GO:0016972 thiol oxidase activity(GO:0016972)
0.4 4.5 GO:0042301 phosphate ion binding(GO:0042301)
0.4 44.0 GO:0005178 integrin binding(GO:0005178)
0.4 7.9 GO:0071837 HMG box domain binding(GO:0071837)
0.4 34.5 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.4 5.2 GO:0016805 dipeptidase activity(GO:0016805)
0.4 3.3 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.4 4.7 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.3 6.5 GO:0004697 protein kinase C activity(GO:0004697)
0.3 8.0 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.3 29.1 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.3 34.2 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.3 36.4 GO:0030165 PDZ domain binding(GO:0030165)
0.3 4.8 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.2 8.2 GO:0008009 chemokine activity(GO:0008009)
0.2 8.1 GO:0005246 calcium channel regulator activity(GO:0005246)
0.2 3.1 GO:0051787 misfolded protein binding(GO:0051787)
0.2 23.7 GO:0002020 protease binding(GO:0002020)
0.2 2.5 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.2 4.2 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.2 1.6 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.2 3.5 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.2 9.5 GO:0005080 protein kinase C binding(GO:0005080)
0.2 4.0 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.2 4.0 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 2.5 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.1 7.6 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.1 1.6 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.1 2.8 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 3.8 GO:0015932 nucleobase-containing compound transmembrane transporter activity(GO:0015932)
0.1 1.4 GO:0004622 lysophospholipase activity(GO:0004622)
0.1 0.5 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.1 16.3 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.1 6.7 GO:0003777 microtubule motor activity(GO:0003777)
0.1 6.7 GO:0019838 growth factor binding(GO:0019838)
0.1 1.6 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.1 0.4 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.1 2.2 GO:0003774 motor activity(GO:0003774)
0.1 1.3 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 2.5 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 46.1 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.3 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 2.9 GO:0016503 pheromone receptor activity(GO:0016503)
0.0 5.3 GO:0008017 microtubule binding(GO:0008017)
0.0 3.0 GO:0047485 protein N-terminus binding(GO:0047485)
0.0 2.4 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 1.6 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0 0.2 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.5 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 6.0 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
1.6 17.7 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
1.5 55.3 PID NECTIN PATHWAY Nectin adhesion pathway
1.2 38.8 PID CDC42 REG PATHWAY Regulation of CDC42 activity
1.2 43.5 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
1.0 50.7 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
1.0 12.7 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
1.0 13.5 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
1.0 72.5 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.9 7.6 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.8 30.5 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.8 20.1 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.8 28.6 PID GLYPICAN 1PATHWAY Glypican 1 network
0.8 15.8 PID ARF 3PATHWAY Arf1 pathway
0.7 10.3 PID IL23 PATHWAY IL23-mediated signaling events
0.7 39.7 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.7 17.0 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.7 27.5 PID RAS PATHWAY Regulation of Ras family activation
0.7 11.9 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.7 7.2 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.7 9.2 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.6 17.2 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.6 7.3 PID FOXO PATHWAY FoxO family signaling
0.6 6.5 PID IGF1 PATHWAY IGF1 pathway
0.6 6.8 PID NETRIN PATHWAY Netrin-mediated signaling events
0.5 8.8 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.5 22.2 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.4 27.0 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.4 3.4 PID IL5 PATHWAY IL5-mediated signaling events
0.4 13.0 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.4 7.0 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.3 14.5 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.3 24.5 PID E2F PATHWAY E2F transcription factor network
0.3 16.5 NABA COLLAGENS Genes encoding collagen proteins
0.3 11.0 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.3 11.5 PID HNF3A PATHWAY FOXA1 transcription factor network
0.3 4.8 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.3 0.3 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.3 9.5 PID TGFBR PATHWAY TGF-beta receptor signaling
0.2 2.8 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.2 4.7 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.2 37.5 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.2 5.9 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.1 2.4 PID AP1 PATHWAY AP-1 transcription factor network
0.1 4.7 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 3.1 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.1 1.5 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.1 1.5 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 2.4 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.5 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 0.5 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 4.2 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 2.1 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 61.5 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
2.6 102.8 REACTOME GLYCOLYSIS Genes involved in Glycolysis
2.1 32.2 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
1.9 65.2 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
1.8 33.4 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
1.6 22.2 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
1.5 17.7 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
1.4 10.1 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
1.4 15.8 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
1.4 23.0 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
1.3 65.5 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
1.2 16.4 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
1.1 35.4 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
1.0 45.1 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
1.0 14.1 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
1.0 9.5 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.9 11.6 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.9 21.7 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.8 25.0 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.8 3.3 REACTOME ADP SIGNALLING THROUGH P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.8 10.9 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.8 9.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.7 26.5 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.7 27.1 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.7 11.9 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.6 57.0 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.6 11.5 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.5 6.8 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.5 11.8 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.5 9.5 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.4 12.4 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.4 4.7 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.3 5.2 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.3 6.2 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.3 5.4 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.3 8.2 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.3 30.2 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.2 2.4 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.2 2.6 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.2 4.3 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.2 6.7 REACTOME KINESINS Genes involved in Kinesins
0.2 1.6 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.2 13.7 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.2 4.5 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.2 23.5 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.2 8.0 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.1 5.7 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 6.1 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.1 7.3 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 2.5 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.1 1.0 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 5.4 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 3.2 REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
0.1 0.9 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.1 9.5 REACTOME GASTRIN CREB SIGNALLING PATHWAY VIA PKC AND MAPK Genes involved in Gastrin-CREB signalling pathway via PKC and MAPK
0.1 11.5 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1 3.8 REACTOME FATTY ACID TRIACYLGLYCEROL AND KETONE BODY METABOLISM Genes involved in Fatty acid, triacylglycerol, and ketone body metabolism
0.0 0.5 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 1.5 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.0 0.3 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.4 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 2.2 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.5 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.2 REACTOME PLATELET AGGREGATION PLUG FORMATION Genes involved in Platelet Aggregation (Plug Formation)
0.0 0.3 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions