Project
GSE53960: rat RNA-Seq transcriptomic Bodymap
Navigation
Downloads
Results for Esrrb_Esrra
Z-value: 3.14
Motif logo
Transcription factors associated with Esrrb_Esrra
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Esrra | rn6_v1_chr1_-_222177421_222177421 | 0.82 | 3.1e-78 | Click! |
| Esrrb | rn6_v1_chr6_+_110410141_110410141 | 0.56 | 1.9e-27 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr9_+_82741920 Show fit | 189.57 |
ENSRNOT00000027337
|
solute carrier family 4 member 3 |
|
| chr15_+_33606124 Show fit | 187.87 |
ENSRNOT00000065210
|
|
|
| chr8_-_130429132 Show fit | 185.75 |
ENSRNOT00000026261
|
hedgehog acyltransferase-like |
|
| chr1_-_263269762 Show fit | 184.27 |
ENSRNOT00000022309
|
glutamic-oxaloacetic transaminase 1 |
|
| chr7_-_80796670 Show fit | 177.78 |
ENSRNOT00000010539
|
actin-binding Rho activating protein |
|
| chr1_-_104157855 Show fit | 149.27 |
ENSRNOT00000019311
|
cysteine and glycine rich protein 3 |
|
| chr7_+_123102493 Show fit | 145.92 |
ENSRNOT00000038612
|
aconitase 2 |
|
| chr13_+_52625441 Show fit | 135.58 |
ENSRNOT00000012095
|
troponin I1, slow skeletal type |
|
| chr13_-_85622314 Show fit | 120.58 |
ENSRNOT00000005719
|
microsomal glutathione S-transferase 3 |
|
| chr4_-_157679962 Show fit | 119.03 |
ENSRNOT00000050443
|
glyceraldehyde-3-phosphate dehydrogenase |
Network of associatons between targets according to the STRING database.
First level regulatory network of Esrrb_Esrra
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 7.8 | 303.3 | GO:0042775 | mitochondrial ATP synthesis coupled electron transport(GO:0042775) |
| 11.7 | 281.7 | GO:0015985 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
| 46.1 | 276.8 | GO:0006102 | isocitrate metabolic process(GO:0006102) |
| 80.1 | 240.3 | GO:0006106 | fumarate metabolic process(GO:0006106) |
| 58.6 | 234.4 | GO:0042776 | mitochondrial ATP synthesis coupled proton transport(GO:0042776) |
| 5.2 | 230.5 | GO:0045214 | sarcomere organization(GO:0045214) |
| 31.0 | 185.8 | GO:1903059 | regulation of protein lipidation(GO:1903059) |
| 5.4 | 177.8 | GO:0035025 | positive regulation of Rho protein signal transduction(GO:0035025) |
| 5.0 | 161.1 | GO:0015701 | bicarbonate transport(GO:0015701) |
| 49.8 | 149.3 | GO:1903918 | regulation of actin filament severing(GO:1903918) negative regulation of actin filament severing(GO:1903919) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 4.5 | 605.8 | GO:0030018 | Z disc(GO:0030018) |
| 1.6 | 413.2 | GO:0005743 | mitochondrial inner membrane(GO:0005743) |
| 7.9 | 393.1 | GO:0030964 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
| 0.3 | 304.7 | GO:0005739 | mitochondrion(GO:0005739) |
| 16.9 | 269.8 | GO:0005751 | mitochondrial respiratory chain complex IV(GO:0005751) |
| 3.8 | 251.9 | GO:0030017 | sarcomere(GO:0030017) |
| 22.3 | 244.9 | GO:0005750 | mitochondrial respiratory chain complex III(GO:0005750) |
| 1.2 | 238.5 | GO:0043679 | axon terminus(GO:0043679) |
| 0.5 | 223.4 | GO:0005635 | nuclear envelope(GO:0005635) |
| 17.1 | 222.7 | GO:0000276 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 10.3 | 309.8 | GO:0004129 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
| 13.4 | 242.0 | GO:0046933 | proton-transporting ATP synthase activity, rotational mechanism(GO:0046933) |
| 75.6 | 226.7 | GO:0004807 | triose-phosphate isomerase activity(GO:0004807) |
| 42.9 | 214.5 | GO:0043532 | angiostatin binding(GO:0043532) |
| 65.3 | 196.0 | GO:0051538 | 3 iron, 4 sulfur cluster binding(GO:0051538) |
| 0.9 | 194.7 | GO:0003779 | actin binding(GO:0003779) |
| 61.4 | 184.3 | GO:0080130 | L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130) |
| 44.3 | 177.1 | GO:0061629 | RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629) |
| 6.4 | 173.0 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
| 6.1 | 170.9 | GO:0005452 | inorganic anion exchanger activity(GO:0005452) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.8 | 182.2 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 1.4 | 91.6 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
| 1.5 | 88.7 | PID HIF1 TFPATHWAY | HIF-1-alpha transcription factor network |
| 3.5 | 72.8 | PID LPA4 PATHWAY | LPA4-mediated signaling events |
| 2.0 | 63.4 | PID INSULIN GLUCOSE PATHWAY | Insulin-mediated glucose transport |
| 1.2 | 52.5 | SIG CD40PATHWAYMAP | Genes related to CD40 signaling |
| 0.9 | 51.1 | PID P53 REGULATION PATHWAY | p53 pathway |
| 1.1 | 48.3 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.3 | 46.6 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 1.3 | 46.5 | PID HDAC CLASSII PATHWAY | Signaling events mediated by HDAC Class II |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 15.4 | 942.3 | REACTOME RESPIRATORY ELECTRON TRANSPORT | Genes involved in Respiratory electron transport |
| 31.5 | 566.7 | REACTOME CITRIC ACID CYCLE TCA CYCLE | Genes involved in Citric acid cycle (TCA cycle) |
| 11.6 | 453.6 | REACTOME GLUCONEOGENESIS | Genes involved in Gluconeogenesis |
| 21.1 | 338.3 | REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING | Genes involved in Formation of ATP by chemiosmotic coupling |
| 8.5 | 331.6 | REACTOME STRIATED MUSCLE CONTRACTION | Genes involved in Striated Muscle Contraction |
| 5.0 | 193.3 | REACTOME MITOCHONDRIAL PROTEIN IMPORT | Genes involved in Mitochondrial Protein Import |
| 1.7 | 181.8 | REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
| 6.2 | 124.2 | REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS | Genes involved in Glycogen breakdown (glycogenolysis) |
| 4.0 | 120.6 | REACTOME GLUTATHIONE CONJUGATION | Genes involved in Glutathione conjugation |
| 5.5 | 114.5 | REACTOME PYRUVATE METABOLISM | Genes involved in Pyruvate metabolism |