ISMARA results: Dlx1

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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Dlx1

Z-value: 1.48

Motif logo

Transcription factors associated with Dlx1

Gene Symbol	Gene ID	Gene Info
Dlx1 NCBI RGD Ensembl	ENSRNOG00000001520	distal-less homeobox 1

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Dlx1	rn6_v1_chr3_+_58164931_58164931	-0.57	2.2e-28	Click!

Activity profile of Dlx1 motif

Sorted Z-values of Dlx1 motif

Top targets:

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr2_-_216348194 Show fit	83.83	ENSRNOT00000087839	LOC103689940 NCBI RGD Ensembl Show fit	pancreatic alpha-amylase-like
chr2_-_216382244 Show fit	71.50	ENSRNOT00000086695 ENSRNOT00000087259	LOC103689940 NCBI RGD Ensembl Show fit	pancreatic alpha-amylase-like
chr11_+_85532526 Show fit	66.86	ENSRNOT00000036565	AABR07034730.2 NCBI RGD Ensembl Show fit
chr3_-_16999720 Show fit	58.80	ENSRNOT00000074382	RGD1563231 NCBI RGD Ensembl Show fit	similar to immunoglobulin kappa-chain VK-1
chr4_-_163049084 Show fit	58.30	ENSRNOT00000091644	Cd69 NCBI RGD Ensembl Show fit	Cd69 molecule
chr6_-_142903440 Show fit	57.57	ENSRNOT00000075707	AABR07065823.2 NCBI RGD Ensembl Show fit
chr3_+_19045214 Show fit	55.75	ENSRNOT00000070878	AABR07051670.1 NCBI RGD Ensembl Show fit
chr18_+_55666027 Show fit	55.36	ENSRNOT00000045950	RGD1305184 NCBI RGD Ensembl Show fit	similar to CDNA sequence BC023105
chr10_-_34242985 Show fit	50.99	ENSRNOT00000046438	RGD1559575 NCBI RGD Ensembl Show fit	similar to novel protein
chr10_-_56506446 Show fit	50.98	ENSRNOT00000021357	Acap1 NCBI RGD Ensembl Show fit	ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
chr9_-_23493081 Show fit	45.97	ENSRNOT00000072144	Rhag NCBI RGD Ensembl Show fit	Rh-associated glycoprotein
chr13_+_48426820 Show fit	45.88	ENSRNOT00000048391	Ctse NCBI RGD Ensembl Show fit	cathepsin E
chr3_+_18970574 Show fit	45.35	ENSRNOT00000088394	AABR07051665.1 NCBI RGD Ensembl Show fit
chr13_+_82369493 Show fit	44.97	ENSRNOT00000003733	Sell NCBI RGD Ensembl Show fit	selectin L
chr6_-_143195445 Show fit	44.88	ENSRNOT00000078672	AABR07065837.1 NCBI RGD Ensembl Show fit
chr3_+_16753703 Show fit	44.16	ENSRNOT00000077741	AABR07051548.2 NCBI RGD Ensembl Show fit
chrX_+_78372257 Show fit	42.97	ENSRNOT00000046164	Gpr174 NCBI RGD Ensembl Show fit	G protein-coupled receptor 174
chr4_+_98481520 Show fit	40.53	ENSRNOT00000078381 ENSRNOT00000048493	AABR07060886.1 NCBI RGD Ensembl Show fit
chr3_+_72395218 Show fit	40.35	ENSRNOT00000057616	Prg3 NCBI RGD Ensembl Show fit	proteoglycan 3, pro eosinophil major basic protein 2
chr3_-_160802433 Show fit	38.13	ENSRNOT00000076191	Slpi NCBI RGD Ensembl Show fit	secretory leukocyte peptidase inhibitor
chr3_+_16846412 Show fit	37.37	ENSRNOT00000074266	AABR07051551.1 NCBI RGD Ensembl Show fit
chr18_+_55463308 Show fit	36.90	ENSRNOT00000073388	LOC100910979 NCBI RGD Ensembl Show fit	interferon-inducible GTPase 1-like
chr4_+_93791054 Show fit	36.84	ENSRNOT00000042300	AABR07060788.1 NCBI RGD Ensembl Show fit
chr18_+_55505993 Show fit	35.96	ENSRNOT00000043736	RGD1309362 NCBI RGD Ensembl Show fit	similar to interferon-inducible GTPase
chr7_-_18793289 Show fit	35.63	ENSRNOT00000036375	AABR07056026.1 NCBI RGD Ensembl Show fit
chr3_+_17889972 Show fit	35.46	ENSRNOT00000073021	AABR07051611.1 NCBI RGD Ensembl Show fit
chr18_+_55391388 Show fit	34.90	ENSRNOT00000071612	LOC100910934 NCBI RGD Ensembl Show fit	interferon-inducible GTPase 1-like
chr3_+_20303979 Show fit	33.60	ENSRNOT00000058331	AABR07051730.1 NCBI RGD Ensembl Show fit
chr11_+_85561460 Show fit	33.29	ENSRNOT00000075455	AABR07072262.1 NCBI RGD Ensembl Show fit
chr3_-_20695952 Show fit	33.20	ENSRNOT00000072306	AABR07051746.1 NCBI RGD Ensembl Show fit
chr3_+_20375699 Show fit	33.04	ENSRNOT00000088492	AABR07051731.1 NCBI RGD Ensembl Show fit
chr16_-_31301880 Show fit	32.71	ENSRNOT00000084847 ENSRNOT00000083943	AABR07025272.1 NCBI RGD Ensembl Show fit
chr3_-_20419417 Show fit	32.65	ENSRNOT00000077772	AABR07051733.3 NCBI RGD Ensembl Show fit
chr6_-_139911839 Show fit	32.64	ENSRNOT00000077113 ENSRNOT00000084547	AABR07065714.1 NCBI RGD Ensembl Show fit
chr4_+_69386698 Show fit	32.51	ENSRNOT00000091655	Trbv13-2 NCBI RGD Ensembl Show fit	T cell receptor beta, variable 13-2
chr6_-_140880070 Show fit	32.30	ENSRNOT00000073779	LOC691828 NCBI RGD Ensembl Show fit	uncharacterized LOC691828
chr13_+_48427038 Show fit	32.20	ENSRNOT00000009241	Ctse NCBI RGD Ensembl Show fit	cathepsin E
chr4_-_164453171 Show fit	31.67	ENSRNOT00000077539 ENSRNOT00000083610 ENSRNOT00000079975	Ly49s6 NCBI RGD Ensembl Show fit	Ly49 stimulatory receptor 6
chr4_-_167202106 Show fit	31.64	ENSRNOT00000038581	Tas2r140 NCBI RGD Ensembl Show fit	taste receptor, type 2, member 140
chr6_-_141147264 Show fit	31.14	ENSRNOT00000042900	LOC100361105 NCBI RGD Ensembl Show fit	Igh protein-like
chr4_+_93959152 Show fit	31.10	ENSRNOT00000058437	AABR07060795.1 NCBI RGD Ensembl Show fit
chr7_-_107392972 Show fit	30.82	ENSRNOT00000093425	Tmem71 NCBI RGD Ensembl Show fit	transmembrane protein 71
chr4_+_101687327 Show fit	30.50	ENSRNOT00000082501	AABR07060957.1 NCBI RGD Ensembl Show fit
chr2_+_187447501 Show fit	30.04	ENSRNOT00000038589	Iqgap3 NCBI RGD Ensembl Show fit	IQ motif containing GTPase activating protein 3
chr1_-_227932603 Show fit	29.86	ENSRNOT00000033795	Ms4a6a NCBI RGD Ensembl Show fit	membrane spanning 4-domains A6A
chr8_-_114617466 Show fit	29.79	ENSRNOT00000082992 ENSRNOT00000038160	Col6a5 NCBI RGD Ensembl Show fit	collagen type VI alpha 5 chain
chr6_+_139405966 Show fit	29.01	ENSRNOT00000088974	AABR07065693.3 NCBI RGD Ensembl Show fit
chr15_-_59215803 Show fit	28.87	ENSRNOT00000032301	Lacc1 NCBI RGD Ensembl Show fit	laccase domain containing 1
chr3_-_148057523 Show fit	28.52	ENSRNOT00000055408	Defb24 NCBI RGD Ensembl Show fit	defensin beta 24
chr14_+_5928737 Show fit	28.46	ENSRNOT00000071877 ENSRNOT00000040985 ENSRNOT00000074889	Mpa2l NCBI RGD Ensembl Show fit	macrophage activation 2 like
chr2_+_223121410 Show fit	28.34	ENSRNOT00000087559	AABR07013116.1 NCBI RGD Ensembl Show fit
chr8_-_104155775 Show fit	28.30	ENSRNOT00000042885	LOC102550734 NCBI RGD Ensembl Show fit	60S ribosomal protein L31-like
chr3_+_19174027 Show fit	27.79	ENSRNOT00000074445	AABR07051678.1 NCBI RGD Ensembl Show fit
chr20_-_1339488 Show fit	27.75	ENSRNOT00000041074	RT1-M2 NCBI RGD Ensembl Show fit	RT1 class Ib, locus M2
chr4_+_102665529 Show fit	27.73	ENSRNOT00000082333	AABR07061005.1 NCBI RGD Ensembl Show fit
chr4_+_22898527 Show fit	27.53	ENSRNOT00000072455 ENSRNOT00000076123	Dbf4 NCBI RGD Ensembl Show fit	DBF4 zinc finger
chr6_-_138852571 Show fit	27.11	ENSRNOT00000081803	AABR07065656.8 NCBI RGD Ensembl Show fit
chr4_+_102262007 Show fit	26.79	ENSRNOT00000079328	AABR07060992.2 NCBI RGD Ensembl Show fit
chr19_+_3325893 Show fit	26.73	ENSRNOT00000048879	RGD1565617 NCBI RGD Ensembl Show fit	similar to Ig variable region, light chain
chr4_-_163463718 Show fit	26.73	ENSRNOT00000085671	Klrc1 NCBI RGD Ensembl Show fit	killer cell lectin like receptor C1
chr2_+_88217188 Show fit	26.65	ENSRNOT00000014267	Car1 NCBI RGD Ensembl Show fit	carbonic anhydrase I
chr15_-_28081465 Show fit	26.43	ENSRNOT00000033739	Rnase6 NCBI RGD Ensembl Show fit	ribonuclease, RNase A family, 6
chr3_-_20479999 Show fit	26.42	ENSRNOT00000050573	AABR07051733.2 NCBI RGD Ensembl Show fit
chr14_-_5859581 Show fit	26.11	ENSRNOT00000052308	AABR07014241.1 NCBI RGD Ensembl Show fit
chr3_-_19320915 Show fit	25.68	ENSRNOT00000043673	RGD1565617 NCBI RGD Ensembl Show fit	similar to Ig variable region, light chain
chr8_+_2604962 Show fit	25.38	ENSRNOT00000009993	Casp1 NCBI RGD Ensembl Show fit	caspase 1
chr3_-_153114520 Show fit	24.70	ENSRNOT00000008254	Dsn1 NCBI RGD Ensembl Show fit	DSN1 homolog, MIS12 kinetochore complex component
chr6_-_141291347 Show fit	24.38	ENSRNOT00000008333	AABR07065789.1 NCBI RGD Ensembl Show fit
chr6_-_143206772 Show fit	24.35	ENSRNOT00000073713	AABR07065839.1 NCBI RGD Ensembl Show fit
chr4_+_101949285 Show fit	23.71	ENSRNOT00000058446	AABR07060963.3 NCBI RGD Ensembl Show fit
chr3_-_166993940 Show fit	23.61	ENSRNOT00000034669	Zfp217 NCBI RGD Ensembl Show fit	zinc finger protein 217
chr9_+_92681078 Show fit	23.29	ENSRNOT00000034152	Sp100 NCBI RGD Ensembl Show fit	SP100 nuclear antigen
chr4_-_163762434 Show fit	23.06	ENSRNOT00000081854	Ly49si1 NCBI RGD Ensembl Show fit	immunoreceptor Ly49si1
chr6_-_139747737 Show fit	23.03	ENSRNOT00000090626	AABR07065705.3 NCBI RGD Ensembl Show fit
chr17_+_24416651 Show fit	23.02	ENSRNOT00000024458	Cd83 NCBI RGD Ensembl Show fit	CD83 molecule
chr3_-_94808861 Show fit	22.99	ENSRNOT00000038464	Prrg4 NCBI RGD Ensembl Show fit	proline rich and Gla domain 4
chr3_+_16571602 Show fit	22.85	ENSRNOT00000048351	LOC100361705 NCBI RGD Ensembl Show fit	rCG64259-like
chr3_-_166994286 Show fit	22.78	ENSRNOT00000081593	Zfp217 NCBI RGD Ensembl Show fit	zinc finger protein 217
chr4_-_164211819 Show fit	22.24	ENSRNOT00000084796	LOC497796 NCBI RGD Ensembl Show fit	hypothetical protein LOC497796
chr10_-_110232843 Show fit	22.16	ENSRNOT00000054934	Cd7 NCBI RGD Ensembl Show fit	Cd7 molecule
chrX_-_135250519 Show fit	21.99	ENSRNOT00000044487	Elf4 NCBI RGD Ensembl Show fit	E74 like ETS transcription factor 4
chr20_+_4020317 Show fit	21.94	ENSRNOT00000000526	RT1-DOb NCBI RGD Ensembl Show fit	RT1 class II, locus DOb
chr2_-_173668555 Show fit	21.44	ENSRNOT00000013452	Serpini2 NCBI RGD Ensembl Show fit	serpin family I member 2
chr15_+_32828165 Show fit	21.34	ENSRNOT00000060253	AABR07017902.1 NCBI RGD Ensembl Show fit
chr1_-_252461461 Show fit	21.33	ENSRNOT00000026093	Ankrd22 NCBI RGD Ensembl Show fit	ankyrin repeat domain 22
chr20_+_4106189 Show fit	21.26	ENSRNOT00000042571	RT1-Db2 NCBI RGD Ensembl Show fit	RT1 class II, locus Db2
chr14_-_21299068 Show fit	21.18	ENSRNOT00000065778	Amtn NCBI RGD Ensembl Show fit	amelotin
chr2_+_240396152 Show fit	21.13	ENSRNOT00000034565	Cenpe NCBI RGD Ensembl Show fit	centromere protein E
chr17_-_12669573 Show fit	21.10	ENSRNOT00000016942 ENSRNOT00000041726	Syk NCBI RGD Ensembl Show fit	spleen associated tyrosine kinase
chr20_+_3155652 Show fit	21.09	ENSRNOT00000042882	RT1-S2 NCBI RGD Ensembl Show fit	RT1 class Ib, locus S2
chr1_-_189182306 Show fit	21.05	ENSRNOT00000021249	Gp2 NCBI RGD Ensembl Show fit	glycoprotein 2
chr4_+_14001761 Show fit	21.02	ENSRNOT00000076519	Cd36 NCBI RGD Ensembl Show fit	CD36 molecule
chr4_-_163849618 Show fit	20.79	ENSRNOT00000086363 ENSRNOT00000077637	Ly49si1 NCBI RGD Ensembl Show fit	immunoreceptor Ly49si1
chr13_-_50916982 Show fit	20.78	ENSRNOT00000004408	Btg2 NCBI RGD Ensembl Show fit	BTG anti-proliferation factor 2
chr6_-_142353308 Show fit	20.76	ENSRNOT00000066416	AABR07065814.2 NCBI RGD Ensembl Show fit
chr11_-_43022565 Show fit	20.75	ENSRNOT00000002285	Riox2 NCBI RGD Ensembl Show fit	ribosomal oxygenase 2
chr8_-_133128290 Show fit	20.49	ENSRNOT00000008783	Ccr1l1 NCBI RGD Ensembl Show fit	chemokine (C-C motif) receptor 1-like 1
chr17_-_28191436 Show fit	20.47	ENSRNOT00000000149	Ly86 NCBI RGD Ensembl Show fit	lymphocyte antigen 86
chr3_-_16753987 Show fit	20.29	ENSRNOT00000091257	AABR07051548.1 NCBI RGD Ensembl Show fit
chr14_+_1937041 Show fit	20.26	ENSRNOT00000000040	Tmed11 NCBI RGD Ensembl Show fit	transmembrane emp24 protein transport domain containing 11
chr6_-_143702033 Show fit	20.23	ENSRNOT00000051410	AABR07065886.1 NCBI RGD Ensembl Show fit
chr3_+_20163337 Show fit	20.18	ENSRNOT00000075136	AABR07051726.1 NCBI RGD Ensembl Show fit
chr2_+_80269661 Show fit	19.98	ENSRNOT00000015975	AABR07008940.1 NCBI RGD Ensembl Show fit
chr9_-_95362014 Show fit	19.95	ENSRNOT00000051065	Hjurp NCBI RGD Ensembl Show fit	Holliday junction recognition protein
chr3_+_19366370 Show fit	19.85	ENSRNOT00000086557	AABR07051689.1 NCBI RGD Ensembl Show fit
chr2_+_206342066 Show fit	19.84	ENSRNOT00000026556	Ptpn22 NCBI RGD Ensembl Show fit	protein tyrosine phosphatase, non-receptor type 22
chr3_+_16817051 Show fit	19.83	ENSRNOT00000071666	AABR07051550.1 NCBI RGD Ensembl Show fit
chr14_+_44889287 Show fit	19.76	ENSRNOT00000091312 ENSRNOT00000032273	Tmem156 NCBI RGD Ensembl Show fit	transmembrane protein 156
chr7_-_143324536 Show fit	19.75	ENSRNOT00000011644	Krt5 NCBI RGD Ensembl Show fit	keratin 5
chr7_-_107385528 Show fit	19.63	ENSRNOT00000093352	Tmem71 NCBI RGD Ensembl Show fit	transmembrane protein 71
chr4_+_102794168 Show fit	19.63	ENSRNOT00000048400	AABR07061022.1 NCBI RGD Ensembl Show fit
chr6_-_142372031 Show fit	19.62	ENSRNOT00000063929	AABR07065814.3 NCBI RGD Ensembl Show fit
chr6_-_125723732 Show fit	19.57	ENSRNOT00000084815	Fbln5 NCBI RGD Ensembl Show fit	fibulin 5
chr3_-_153001309 Show fit	19.43	ENSRNOT00000027581	Sla2 NCBI RGD Ensembl Show fit	Src-like-adaptor 2
chr11_-_14304603 Show fit	19.34	ENSRNOT00000040202 ENSRNOT00000082143	Samsn1 NCBI RGD Ensembl Show fit	SAM domain, SH3 domain and nuclear localization signals, 1
chr5_-_151459037 Show fit	19.23	ENSRNOT00000064472 ENSRNOT00000087836	Sytl1 NCBI RGD Ensembl Show fit	synaptotagmin-like 1
chr8_+_22559098 Show fit	19.00	ENSRNOT00000041091	LOC691141 NCBI RGD Ensembl Show fit	hypothetical protein LOC691141
chr1_+_22332090 Show fit	18.78	ENSRNOT00000091252	AABR07000663.1 NCBI RGD Ensembl Show fit	trace amine-associated receptor 8c (Taar8c), mRNA
chr5_+_24410863 Show fit	18.76	ENSRNOT00000010591	Tp53inp1 NCBI RGD Ensembl Show fit	tumor protein p53 inducible nuclear protein 1
chr6_-_142585188 Show fit	18.68	ENSRNOT00000067437	AABR07065815.1 NCBI RGD Ensembl Show fit
chr14_+_76732650 Show fit	18.61	ENSRNOT00000088197	Clnk NCBI RGD Ensembl Show fit	cytokine-dependent hematopoietic cell linker
chr4_-_164406146 Show fit	18.60	ENSRNOT00000090110	Klra22 NCBI RGD Ensembl Show fit	killer cell lectin-like receptor subfamily A, member 22
chr1_+_196095214 Show fit	18.52	ENSRNOT00000080741	LOC691716 NCBI RGD Ensembl Show fit	similar to ribosomal protein S15a
chr11_+_85042348 Show fit	18.50	ENSRNOT00000042220	AABR07034718.1 NCBI RGD Ensembl Show fit
chr10_+_34277993 Show fit	18.34	ENSRNOT00000055872 ENSRNOT00000003343	Ifi47 NCBI RGD Ensembl Show fit	interferon gamma inducible protein 47
chr10_-_67401836 Show fit	18.16	ENSRNOT00000073071	Crlf3 NCBI RGD Ensembl Show fit	cytokine receptor-like factor 3
chr13_+_82438697 Show fit	18.14	ENSRNOT00000003759	Selp NCBI RGD Ensembl Show fit	selectin P
chr4_+_101531378 Show fit	18.12	ENSRNOT00000087546	AABR07060944.1 NCBI RGD Ensembl Show fit
chr9_+_71915421 Show fit	17.99	ENSRNOT00000020447	Pikfyve NCBI RGD Ensembl Show fit	phosphoinositide kinase, FYVE-type zinc finger containing
chr9_+_67774150 Show fit	17.94	ENSRNOT00000091060	Icos NCBI RGD Ensembl Show fit	inducible T-cell co-stimulator
chr16_+_2634603 Show fit	17.94	ENSRNOT00000019113	Hesx1 NCBI RGD Ensembl Show fit	HESX homeobox 1
chr4_-_163954817 Show fit	17.79	ENSRNOT00000079951	Ly49si3 NCBI RGD Ensembl Show fit	immunoreceptor Ly49si3
chr2_-_149432106 Show fit	17.64	ENSRNOT00000051027	P2ry13 NCBI RGD Ensembl Show fit	purinergic receptor P2Y13
chr1_+_15834779 Show fit	17.54	ENSRNOT00000079069 ENSRNOT00000083012	Bclaf1 NCBI RGD Ensembl Show fit	BCL2-associated transcription factor 1
chr15_-_29446332 Show fit	17.51	ENSRNOT00000082901	AABR07017634.1 NCBI RGD Ensembl Show fit
chr10_-_29026002 Show fit	17.31	ENSRNOT00000005070	Pttg1 NCBI RGD Ensembl Show fit	pituitary tumor-transforming 1
chr4_-_103761881 Show fit	17.18	ENSRNOT00000084103	AABR07061087.1 NCBI RGD Ensembl Show fit
chr11_-_28900376 Show fit	17.08	ENSRNOT00000061606	Krtap16-5 NCBI RGD Ensembl Show fit	keratin associated protein 16-5
chr2_-_60657712 Show fit	17.05	ENSRNOT00000040348	Rai14 NCBI RGD Ensembl Show fit	retinoic acid induced 14
chr1_+_227240383 Show fit	16.99	ENSRNOT00000074127	Ms4a6e NCBI RGD Ensembl Show fit	membrane spanning 4-domains A6E
chr3_+_18787606 Show fit	16.86	ENSRNOT00000090508	AABR07051658.1 NCBI RGD Ensembl Show fit
chr4_+_162077188 Show fit	16.82	ENSRNOT00000090431	LOC100910725 NCBI RGD Ensembl Show fit	C-type lectin domain family 2 member D-related protein-like
chr10_-_90307658 Show fit	16.67	ENSRNOT00000092102	Slc4a1 NCBI RGD Ensembl Show fit	solute carrier family 4 member 1
chr16_+_29674793 Show fit	16.53	ENSRNOT00000059724	Anxa10 NCBI RGD Ensembl Show fit	annexin A10
chr10_-_87564327 Show fit	16.42	ENSRNOT00000064760 ENSRNOT00000068237	LOC680160 NCBI RGD Ensembl Show fit	similar to keratin associated protein 4-7
chr6_-_138764901 Show fit	16.31	ENSRNOT00000075175	AABR07065651.2 NCBI RGD Ensembl Show fit
chrX_+_105011489 Show fit	16.28	ENSRNOT00000085068	Arl13a NCBI RGD Ensembl Show fit	ADP ribosylation factor like GTPase 13A
chr20_+_3176107 Show fit	16.26	ENSRNOT00000001036	RT1-S3 NCBI RGD Ensembl Show fit	RT1 class Ib, locus S3
chr3_+_17139670 Show fit	16.25	ENSRNOT00000073316	AABR07051564.1 NCBI RGD Ensembl Show fit
chr15_+_61826937 Show fit	16.12	ENSRNOT00000084005 ENSRNOT00000079417	Elf1 NCBI RGD Ensembl Show fit	E74-like factor 1
chr9_+_91001828 Show fit	16.05	ENSRNOT00000080956	AABR07068214.1 NCBI RGD Ensembl Show fit
chr4_+_169147243 Show fit	16.04	ENSRNOT00000011580	Emp1 NCBI RGD Ensembl Show fit	epithelial membrane protein 1
chr1_+_141767940 Show fit	15.96	ENSRNOT00000064034	Zfp710 NCBI RGD Ensembl Show fit	zinc finger protein 710
chr10_-_56270640 Show fit	15.91	ENSRNOT00000056918	Cd68 NCBI RGD Ensembl Show fit	Cd68 molecule
chr4_-_164049599 Show fit	15.91	ENSRNOT00000078267	AABR07062183.1 NCBI RGD Ensembl Show fit
chr5_+_126668689 Show fit	15.75	ENSRNOT00000036072	Cyb5rl NCBI RGD Ensembl Show fit	cytochrome b5 reductase-like
chr11_+_31539016 Show fit	15.66	ENSRNOT00000072856	Ifnar2 NCBI RGD Ensembl Show fit	interferon alpha and beta receptor subunit 2
chr1_-_198450047 Show fit	15.53	ENSRNOT00000027360	Mvp NCBI RGD Ensembl Show fit	major vault protein
chr1_+_201660042 Show fit	15.52	ENSRNOT00000093289 ENSRNOT00000054910	Dmbt1 NCBI RGD Ensembl Show fit	deleted in malignant brain tumors 1
chr4_+_93888502 Show fit	15.45	ENSRNOT00000090783	AABR07060792.1 NCBI RGD Ensembl Show fit
chr1_+_86938138 Show fit	15.44	ENSRNOT00000075601	Ccer2 NCBI RGD Ensembl Show fit	coiled-coil glutamate-rich protein 2
chr18_+_16330615 Show fit	15.26	ENSRNOT00000049689	RGD1559877 NCBI RGD Ensembl Show fit	similar to 60S ribosomal protein L29 (P23)
chr9_+_65614142 Show fit	15.19	ENSRNOT00000016613	Casp8 NCBI RGD Ensembl Show fit	caspase 8
chr1_+_253221812 Show fit	15.05	ENSRNOT00000085880 ENSRNOT00000054753	Kif20b NCBI RGD Ensembl Show fit	kinesin family member 20B
chr2_-_182846061 Show fit	15.02	ENSRNOT00000013025	Tlr2 NCBI RGD Ensembl Show fit	toll-like receptor 2
chr4_-_162230859 Show fit	14.97	ENSRNOT00000042872	LOC689757 NCBI RGD Ensembl Show fit	similar to osteoclast inhibitory lectin
chrX_-_157200981 Show fit	14.96	ENSRNOT00000087364	AABR07071935.1 NCBI RGD Ensembl Show fit
chr1_-_99587205 Show fit	14.83	ENSRNOT00000048947	Siglec8 NCBI RGD Ensembl Show fit	sialic acid binding Ig-like lectin 8
chr3_+_17180411 Show fit	14.80	ENSRNOT00000058260	AABR07051565.1 NCBI RGD Ensembl Show fit
chr6_-_140215907 Show fit	14.78	ENSRNOT00000086370	AABR07065750.1 NCBI RGD Ensembl Show fit
chr8_+_22368745 Show fit	14.71	ENSRNOT00000049973	Slc44a2 NCBI RGD Ensembl Show fit	solute carrier family 44 member 2
chr20_+_3246739 Show fit	14.71	ENSRNOT00000061299	RT1-T24-2 NCBI RGD Ensembl Show fit	RT1 class I, locus T24, gene 2
chr10_+_31880918 Show fit	14.68	ENSRNOT00000059448	Timd4 NCBI RGD Ensembl Show fit	T-cell immunoglobulin and mucin domain containing 4
chr10_+_69412017 Show fit	14.64	ENSRNOT00000009448	Ccl2 NCBI RGD Ensembl Show fit	C-C motif chemokine ligand 2
chr11_+_88131960 Show fit	14.58	ENSRNOT00000046664	RGD1308065 NCBI RGD Ensembl Show fit	hypothetical LOC287935
chr5_-_12172009 Show fit	14.49	ENSRNOT00000061903	Pcmtd1 NCBI RGD Ensembl Show fit	protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1
chr9_-_82345262 Show fit	14.43	ENSRNOT00000024975	Cnppd1 NCBI RGD Ensembl Show fit	cyclin Pas1/PHO80 domain containing 1
chr4_+_169161585 Show fit	14.35	ENSRNOT00000079785	Emp1 NCBI RGD Ensembl Show fit	epithelial membrane protein 1
chr13_-_83457888 Show fit	14.18	ENSRNOT00000076289 ENSRNOT00000004065	Sft2d2 NCBI RGD Ensembl Show fit	SFT2 domain containing 2
chr16_+_90613870 Show fit	14.16	ENSRNOT00000079334	Shcbp1 NCBI RGD Ensembl Show fit	SHC binding and spindle associated 1
chr7_+_140608434 Show fit	14.14	ENSRNOT00000001163	AC114446.1 NCBI RGD Ensembl Show fit
chr4_-_163810403 Show fit	14.08	ENSRNOT00000079704	AABR07062170.1 NCBI RGD Ensembl Show fit
chr1_-_43638161 Show fit	13.93	ENSRNOT00000024460	Ipcef1 NCBI RGD Ensembl Show fit	interaction protein for cytohesin exchange factors 1
chr20_-_6257604 Show fit	13.88	ENSRNOT00000092489	Stk38 NCBI RGD Ensembl Show fit	serine/threonine kinase 38
chr7_+_16404755 Show fit	13.86	ENSRNOT00000044977	LOC108349290 NCBI RGD Ensembl Show fit	olfactory receptor 6C70-like
chr1_-_189181901 Show fit	13.70	ENSRNOT00000092022	Gp2 NCBI RGD Ensembl Show fit	glycoprotein 2
chr4_-_70659252 Show fit	13.70	ENSRNOT00000048049	Try10 NCBI RGD Ensembl Show fit	trypsin 10
chr5_+_50381244 Show fit	13.62	ENSRNOT00000012385	Cga NCBI RGD Ensembl Show fit	glycoprotein hormones, alpha polypeptide
chr14_-_21252538 Show fit	13.58	ENSRNOT00000005003	Ambn NCBI RGD Ensembl Show fit	ameloblastin
chr18_+_79773608 Show fit	13.53	ENSRNOT00000088484	Zfp516 NCBI RGD Ensembl Show fit	zinc finger protein 516
chr4_-_164691405 Show fit	13.42	ENSRNOT00000090979 ENSRNOT00000091932 ENSRNOT00000078219	Ly49s4 NCBI RGD Ensembl Show fit Ly49i2 NCBI RGD Ensembl Show fit	Ly49 stimulatory receptor 4 Ly49 inhibitory receptor 2
chr10_-_56962161 Show fit	13.41	ENSRNOT00000026038	Alox15 NCBI RGD Ensembl Show fit	arachidonate 15-lipoxygenase
chr10_+_55626741 Show fit	13.36	ENSRNOT00000008492	Aurkb NCBI RGD Ensembl Show fit	aurora kinase B
chr13_-_91735361 Show fit	13.33	ENSRNOT00000058090	Fcer1a NCBI RGD Ensembl Show fit	Fc fragment of IgE receptor Ia
chr3_+_18805220 Show fit	13.30	ENSRNOT00000071216	Igkv4-86 NCBI RGD Ensembl Show fit	immunoglobulin kappa variable 4-86
chr8_+_22648323 Show fit	13.20	ENSRNOT00000013165	Smarca4 NCBI RGD Ensembl Show fit	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
chr13_-_99101208 Show fit	13.05	ENSRNOT00000004329	H3f3a NCBI RGD Ensembl Show fit	H3 histone family member 3A
chr17_+_25082056 Show fit	13.04	ENSRNOT00000037041	AABR07027339.1 NCBI RGD Ensembl Show fit
chr7_+_144865608 Show fit	13.04	ENSRNOT00000091596 ENSRNOT00000055285	Hnrnpa1 NCBI RGD Ensembl Show fit	heterogeneous nuclear ribonucleoprotein A1
chr13_+_89386023 Show fit	13.04	ENSRNOT00000086223	Fcgr3a NCBI RGD Ensembl Show fit	Fc fragment of IgG receptor IIIa

Network of associatons between targets according to the STRING database.

First level regulatory network of Dlx1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
13.5	40.4	GO:0045575	basophil activation(GO:0045575)
11.5	34.4	GO:0045425	positive regulation of interleukin-3 production(GO:0032752) interleukin-3 biosynthetic process(GO:0042223) regulation of interleukin-3 biosynthetic process(GO:0045399) positive regulation of interleukin-3 biosynthetic process(GO:0045401) positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425)
8.7	34.8	GO:0002386	immune response in mucosal-associated lymphoid tissue(GO:0002386)
7.8	23.3	GO:1902044	regulation of Fas signaling pathway(GO:1902044)
7.3	66.0	GO:0070543	response to linoleic acid(GO:0070543)
7.3	21.9	GO:0002581	negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
7.3	21.8	GO:0070175	positive regulation of enamel mineralization(GO:0070175)
7.2	36.1	GO:2000566	positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566)
6.6	6.6	GO:0032672	regulation of interleukin-3 production(GO:0032672)
6.6	46.0	GO:0015670	carbon dioxide transport(GO:0015670)
6.3	25.4	GO:0050717	positive regulation of interleukin-1 alpha secretion(GO:0050717)
6.3	18.8	GO:0036446	myofibroblast differentiation(GO:0036446) response to methyl methanesulfonate(GO:0072702) cellular response to methyl methanesulfonate(GO:0072703) regulation of myofibroblast differentiation(GO:1904760)
5.5	16.4	GO:0098507	polynucleotide 5' dephosphorylation(GO:0098507)
5.5	32.9	GO:1902101	positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
5.2	78.1	GO:0016540	protein autoprocessing(GO:0016540)
5.0	15.1	GO:0033123	positive regulation of purine nucleotide catabolic process(GO:0033123)
5.0	15.1	GO:1902412	regulation of mitotic cytokinesis(GO:1902412)
5.0	15.0	GO:0042496	central nervous system myelin formation(GO:0032289) positive regulation of interleukin-18 production(GO:0032741) detection of diacyl bacterial lipopeptide(GO:0042496) detection of bacterial lipopeptide(GO:0070340)
5.0	20.0	GO:0061641	CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
4.9	14.8	GO:0060101	negative regulation of phagocytosis, engulfment(GO:0060101)
4.9	14.6	GO:2000502	negative regulation of natural killer cell chemotaxis(GO:2000502)
4.4	13.2	GO:1902659	regulation of glucose mediated signaling pathway(GO:1902659)
4.3	12.8	GO:1903595	pancreatic amylase secretion(GO:0036395) regulation of pancreatic amylase secretion(GO:1902276) positive regulation of histamine secretion by mast cell(GO:1903595)
4.2	16.7	GO:0010037	response to carbon dioxide(GO:0010037)
4.2	153.9	GO:0035458	cellular response to interferon-beta(GO:0035458)
4.1	56.8	GO:0001867	complement activation, lectin pathway(GO:0001867)
4.0	24.3	GO:0001866	NK T cell proliferation(GO:0001866)
3.7	37.1	GO:0048251	elastic fiber assembly(GO:0048251)
3.6	10.8	GO:2000424	regulation of eosinophil chemotaxis(GO:2000422) positive regulation of eosinophil chemotaxis(GO:2000424)
3.6	10.8	GO:1902167	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902167)
3.4	20.5	GO:0031666	positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
3.3	23.0	GO:0032713	negative regulation of interleukin-4 production(GO:0032713)
3.3	13.0	GO:1903936	cellular response to sodium arsenite(GO:1903936)
3.2	9.5	GO:0072344	rescue of stalled ribosome(GO:0072344)
3.2	15.8	GO:0060623	regulation of chromosome condensation(GO:0060623)
3.1	15.6	GO:0060478	acrosomal vesicle exocytosis(GO:0060478)
3.0	11.8	GO:0032661	regulation of interleukin-18 production(GO:0032661)
2.9	11.7	GO:1900245	positive regulation of MDA-5 signaling pathway(GO:1900245)
2.9	11.5	GO:0043988	histone H3-S28 phosphorylation(GO:0043988)
2.8	16.6	GO:1901898	negative regulation of relaxation of cardiac muscle(GO:1901898)
2.7	13.4	GO:0051122	hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
2.6	7.8	GO:0060383	positive regulation of DNA strand elongation(GO:0060383)
2.6	18.0	GO:0030916	otic vesicle formation(GO:0030916)
2.5	24.5	GO:0070544	histone H3-K36 demethylation(GO:0070544)
2.3	6.9	GO:2000464	positive regulation of astrocyte chemotaxis(GO:2000464)
2.3	6.8	GO:1901726	negative regulation of histone deacetylase activity(GO:1901726)
2.2	11.1	GO:0061743	motor learning(GO:0061743)
2.2	6.5	GO:2000259	activation of membrane attack complex(GO:0001905) regulation of activation of membrane attack complex(GO:0001969) positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
2.1	8.6	GO:1900170	negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
2.1	4.3	GO:0060003	copper ion export(GO:0060003)
2.1	16.8	GO:0042270	protection from natural killer cell mediated cytotoxicity(GO:0042270)
2.1	16.7	GO:0010606	positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
2.0	10.2	GO:0019371	cyclooxygenase pathway(GO:0019371)
2.0	22.4	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
2.0	4.0	GO:0000294	nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294)
2.0	12.1	GO:2000483	negative regulation of interleukin-8 secretion(GO:2000483)
1.9	11.7	GO:0031087	deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
1.9	5.8	GO:0009099	branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
1.9	3.8	GO:2000328	regulation of T-helper 17 cell lineage commitment(GO:2000328)
1.9	20.8	GO:0060211	regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
1.9	9.4	GO:0031119	tRNA pseudouridine synthesis(GO:0031119)
1.9	22.2	GO:0033601	positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
1.8	9.1	GO:0060327	cytoplasmic actin-based contraction involved in cell motility(GO:0060327)
1.8	25.4	GO:0038094	Fc-gamma receptor signaling pathway(GO:0038094)
1.8	7.1	GO:0071802	negative regulation of podosome assembly(GO:0071802)
1.7	10.3	GO:0061737	leukotriene signaling pathway(GO:0061737)
1.6	6.5	GO:0097680	double-strand break repair via classical nonhomologous end joining(GO:0097680)
1.6	4.9	GO:1904976	cellular response to bleomycin(GO:1904976)
1.6	26.1	GO:0032060	bleb assembly(GO:0032060)
1.6	4.9	GO:0060488	orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
1.6	4.8	GO:0006933	negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
1.6	4.8	GO:0060435	branchiomeric skeletal muscle development(GO:0014707) bronchiole development(GO:0060435)
1.6	15.7	GO:0035456	response to interferon-beta(GO:0035456)
1.6	15.5	GO:0031953	negative regulation of protein autophosphorylation(GO:0031953)
1.5	4.5	GO:0006663	platelet activating factor biosynthetic process(GO:0006663)
1.5	19.4	GO:0050849	negative regulation of calcium-mediated signaling(GO:0050849)
1.5	14.9	GO:0090070	positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
1.5	20.5	GO:0090026	positive regulation of monocyte chemotaxis(GO:0090026)
1.4	8.6	GO:0043305	negative regulation of mast cell degranulation(GO:0043305)
1.4	4.3	GO:0018199	peptidyl-glutamine modification(GO:0018199)
1.4	4.3	GO:0002540	leukotriene production involved in inflammatory response(GO:0002540)
1.4	7.0	GO:1900194	negative regulation of oocyte maturation(GO:1900194)
1.4	9.6	GO:0000459	exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467)
1.3	6.6	GO:0010032	meiotic chromosome condensation(GO:0010032)
1.3	8.0	GO:0071460	cellular response to cell-matrix adhesion(GO:0071460)
1.3	4.0	GO:0014908	myotube differentiation involved in skeletal muscle regeneration(GO:0014908)
1.3	5.3	GO:0009181	purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
1.3	6.5	GO:0038145	macrophage colony-stimulating factor signaling pathway(GO:0038145)
1.3	18.1	GO:0033623	regulation of integrin activation(GO:0033623)
1.3	5.2	GO:2000354	regulation of ovarian follicle development(GO:2000354)
1.3	6.4	GO:0032020	ISG15-protein conjugation(GO:0032020)
1.3	10.0	GO:0031848	protection from non-homologous end joining at telomere(GO:0031848)
1.2	7.5	GO:0042908	xenobiotic transport(GO:0042908)
1.2	9.9	GO:0097264	self proteolysis(GO:0097264)
1.2	3.7	GO:0032910	transforming growth factor beta3 production(GO:0032907) regulation of transforming growth factor beta3 production(GO:0032910) positive regulation of transforming growth factor beta3 production(GO:0032916)
1.2	9.8	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
1.2	20.7	GO:0006590	thyroid hormone generation(GO:0006590)
1.2	3.5	GO:1901367	response to L-cysteine(GO:1901367)
1.2	15.2	GO:0036462	TRAIL-activated apoptotic signaling pathway(GO:0036462)
1.2	12.8	GO:0045059	positive thymic T cell selection(GO:0045059)
1.2	4.7	GO:1903334	positive regulation of protein folding(GO:1903334)
1.2	9.3	GO:0051136	regulation of NK T cell differentiation(GO:0051136)
1.1	16.1	GO:0002517	T cell tolerance induction(GO:0002517)
1.1	5.7	GO:0035617	stress granule disassembly(GO:0035617)
1.1	37.1	GO:0019731	antibacterial humoral response(GO:0019731)
1.1	5.6	GO:0035188	blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
1.1	40.5	GO:0002474	antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
1.0	6.2	GO:0002729	positive regulation of natural killer cell cytokine production(GO:0002729)
1.0	5.1	GO:0010571	positive regulation of nuclear cell cycle DNA replication(GO:0010571)
1.0	21.3	GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504)
1.0	19.8	GO:0001833	inner cell mass cell proliferation(GO:0001833)
1.0	4.8	GO:0006311	meiotic gene conversion(GO:0006311) gene conversion(GO:0035822)
1.0	11.6	GO:0014029	neural crest formation(GO:0014029)
1.0	9.6	GO:1900017	positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.9	7.4	GO:0061087	positive regulation of histone H3-K27 methylation(GO:0061087)
0.9	9.0	GO:0016266	O-glycan processing(GO:0016266)
0.9	4.4	GO:1903251	multi-ciliated epithelial cell differentiation(GO:1903251)
0.9	2.6	GO:0042222	interleukin-1 biosynthetic process(GO:0042222) thymocyte migration(GO:0072679)
0.9	5.2	GO:0031584	activation of phospholipase D activity(GO:0031584)
0.8	6.8	GO:0000395	mRNA 5'-splice site recognition(GO:0000395)
0.8	1.7	GO:0044565	dendritic cell proliferation(GO:0044565)
0.8	16.1	GO:0050860	negative regulation of T cell receptor signaling pathway(GO:0050860)
0.8	2.4	GO:0039533	regulation of MDA-5 signaling pathway(GO:0039533) negative regulation of MDA-5 signaling pathway(GO:0039534)
0.8	9.5	GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.8	7.0	GO:0032790	ribosome disassembly(GO:0032790)
0.8	28.7	GO:0006730	one-carbon metabolic process(GO:0006730)
0.8	2.3	GO:0006438	valyl-tRNA aminoacylation(GO:0006438)
0.8	36.8	GO:0050830	defense response to Gram-positive bacterium(GO:0050830)
0.7	2.2	GO:1902963	regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902959) positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963) regulation of aspartic-type peptidase activity(GO:1905245) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.7	6.0	GO:0051694	pointed-end actin filament capping(GO:0051694)
0.7	1.5	GO:0071393	cellular response to progesterone stimulus(GO:0071393)
0.7	3.7	GO:0000270	peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.7	2.9	GO:0032962	positive regulation of inositol trisphosphate biosynthetic process(GO:0032962)
0.7	4.3	GO:0014732	skeletal muscle atrophy(GO:0014732)
0.7	12.2	GO:0048026	positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.7	7.8	GO:0032674	regulation of interleukin-5 production(GO:0032674)
0.7	2.8	GO:0055005	ventricular cardiac myofibril assembly(GO:0055005)
0.7	4.2	GO:1902035	positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.7	19.3	GO:0002820	negative regulation of adaptive immune response(GO:0002820)
0.7	17.9	GO:0007064	mitotic sister chromatid cohesion(GO:0007064)
0.7	4.1	GO:0006681	galactosylceramide metabolic process(GO:0006681)
0.7	3.9	GO:0097039	protein linear polyubiquitination(GO:0097039)
0.6	10.4	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.6	4.5	GO:1904749	regulation of protein localization to nucleolus(GO:1904749)
0.6	1.3	GO:0051660	establishment of centrosome localization(GO:0051660)
0.6	1.9	GO:0003220	left ventricular cardiac muscle tissue morphogenesis(GO:0003220) cell proliferation involved in heart valve morphogenesis(GO:0003249) regulation of cell proliferation involved in heart valve morphogenesis(GO:0003250) gonad morphogenesis(GO:0035262) nephrogenic mesenchyme morphogenesis(GO:0072134)
0.6	4.7	GO:2000253	positive regulation of feeding behavior(GO:2000253)
0.6	8.3	GO:0035634	response to stilbenoid(GO:0035634)
0.6	15.8	GO:0031572	mitotic G2 DNA damage checkpoint(GO:0007095) G2 DNA damage checkpoint(GO:0031572)
0.6	1.8	GO:1901873	negative regulation of cellular respiration(GO:1901856) regulation of post-translational protein modification(GO:1901873) negative regulation of ATP biosynthetic process(GO:2001170)
0.6	18.0	GO:0046854	phosphatidylinositol phosphorylation(GO:0046854)
0.6	2.8	GO:1903401	L-lysine transmembrane transport(GO:1903401)
0.6	8.9	GO:0002675	positive regulation of acute inflammatory response(GO:0002675)
0.5	5.5	GO:2000042	negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.5	23.4	GO:0048873	homeostasis of number of cells within a tissue(GO:0048873)
0.5	4.3	GO:0019388	galactose catabolic process(GO:0019388)
0.5	4.3	GO:0008616	queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.5	18.2	GO:0046427	positive regulation of JAK-STAT cascade(GO:0046427) positive regulation of STAT cascade(GO:1904894)
0.5	6.8	GO:0010310	regulation of hydrogen peroxide metabolic process(GO:0010310)
0.5	3.7	GO:2000389	regulation of neutrophil extravasation(GO:2000389)
0.5	1.5	GO:0046356	coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034) acetyl-CoA catabolic process(GO:0046356)
0.5	2.6	GO:0032049	cardiolipin biosynthetic process(GO:0032049)
0.5	20.8	GO:0043029	T cell homeostasis(GO:0043029)
0.5	5.1	GO:0035562	negative regulation of chromatin binding(GO:0035562)
0.5	6.0	GO:0006353	DNA-templated transcription, termination(GO:0006353)
0.5	4.5	GO:0071028	nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.5	4.9	GO:0045647	negative regulation of erythrocyte differentiation(GO:0045647)
0.5	2.4	GO:0000706	meiotic DNA double-strand break processing(GO:0000706)
0.5	5.4	GO:0006337	nucleosome disassembly(GO:0006337)
0.4	0.9	GO:0016078	tRNA catabolic process(GO:0016078)
0.4	2.2	GO:0007197	adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.4	6.8	GO:0060218	hematopoietic stem cell differentiation(GO:0060218)
0.4	5.0	GO:1900363	regulation of mRNA polyadenylation(GO:1900363)
0.4	11.8	GO:0030866	cortical actin cytoskeleton organization(GO:0030866)
0.4	5.2	GO:0051988	regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.4	1.2	GO:0090247	cell motility involved in somitogenic axis elongation(GO:0090247) regulation of cell motility involved in somitogenic axis elongation(GO:0090249)
0.4	1.9	GO:0032252	secretory granule localization(GO:0032252)
0.4	1.5	GO:0006564	L-serine biosynthetic process(GO:0006564)
0.4	6.7	GO:0015695	organic cation transport(GO:0015695)
0.4	11.1	GO:0033119	negative regulation of RNA splicing(GO:0033119)
0.4	0.7	GO:0019883	antigen processing and presentation of endogenous antigen(GO:0019883)
0.4	5.7	GO:0030150	protein import into mitochondrial matrix(GO:0030150)
0.4	2.1	GO:0045086	positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.4	2.1	GO:0030397	membrane disassembly(GO:0030397) nuclear envelope disassembly(GO:0051081)
0.4	6.0	GO:0006825	copper ion transport(GO:0006825)
0.3	8.0	GO:0046827	positive regulation of protein export from nucleus(GO:0046827)
0.3	1.0	GO:0010034	response to acetate(GO:0010034)
0.3	1.7	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.3	2.7	GO:0040033	miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.3	1.9	GO:0046836	glycolipid transport(GO:0046836)
0.3	10.3	GO:0000387	spliceosomal snRNP assembly(GO:0000387)
0.3	2.5	GO:0010835	regulation of protein ADP-ribosylation(GO:0010835)
0.3	13.5	GO:0050873	brown fat cell differentiation(GO:0050873)
0.3	1.5	GO:0010841	positive regulation of circadian sleep/wake cycle, wakefulness(GO:0010841)
0.3	3.3	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
0.3	3.9	GO:0001778	plasma membrane repair(GO:0001778)
0.3	1.2	GO:1903758	negative regulation of histone H4 acetylation(GO:0090241) regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.3	0.9	GO:2001201	regulation of transforming growth factor-beta secretion(GO:2001201)
0.3	8.4	GO:0000028	ribosomal small subunit assembly(GO:0000028)
0.3	4.2	GO:0046339	diacylglycerol metabolic process(GO:0046339)
0.3	1.7	GO:0051001	negative regulation of nitric-oxide synthase activity(GO:0051001)
0.3	1.7	GO:0000711	meiotic DNA repair synthesis(GO:0000711)
0.3	12.4	GO:0033344	cholesterol efflux(GO:0033344)
0.3	4.8	GO:0006895	Golgi to endosome transport(GO:0006895)
0.3	1.3	GO:2000741	positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.3	8.4	GO:0043044	ATP-dependent chromatin remodeling(GO:0043044)
0.3	6.4	GO:0051443	positive regulation of ubiquitin-protein transferase activity(GO:0051443)
0.3	2.3	GO:0009048	dosage compensation by inactivation of X chromosome(GO:0009048)
0.3	1.8	GO:0061484	hematopoietic stem cell homeostasis(GO:0061484)
0.3	4.0	GO:0001675	acrosome assembly(GO:0001675)
0.3	4.5	GO:0010960	magnesium ion homeostasis(GO:0010960)
0.3	2.5	GO:1904153	negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.3	3.3	GO:0042407	cristae formation(GO:0042407)
0.2	3.0	GO:0048733	sebaceous gland development(GO:0048733)
0.2	2.5	GO:1904177	regulation of adipose tissue development(GO:1904177)
0.2	15.9	GO:0008543	fibroblast growth factor receptor signaling pathway(GO:0008543)
0.2	6.4	GO:0035025	positive regulation of Rho protein signal transduction(GO:0035025)
0.2	5.2	GO:0042119	neutrophil activation(GO:0042119)
0.2	4.4	GO:0060216	definitive hemopoiesis(GO:0060216)
0.2	4.9	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.2	0.9	GO:0045839	negative regulation of mitotic nuclear division(GO:0045839)
0.2	11.2	GO:0007004	RNA-dependent DNA biosynthetic process(GO:0006278) telomere maintenance via telomerase(GO:0007004)
0.2	2.1	GO:0042118	endothelial cell activation(GO:0042118)
0.2	3.6	GO:0043586	tongue development(GO:0043586)
0.2	1.1	GO:0002726	positive regulation of T cell cytokine production(GO:0002726) ripoptosome assembly(GO:0097343) ripoptosome assembly involved in necroptotic process(GO:1901026)
0.2	1.5	GO:0034983	peptidyl-lysine deacetylation(GO:0034983)
0.2	14.7	GO:2001022	positive regulation of response to DNA damage stimulus(GO:2001022)
0.2	3.2	GO:0060294	cilium movement involved in cell motility(GO:0060294)
0.2	1.0	GO:0035948	positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.2	19.9	GO:0090501	RNA phosphodiester bond hydrolysis(GO:0090501)
0.2	14.8	GO:0043484	regulation of RNA splicing(GO:0043484)
0.2	10.2	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.2	10.5	GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
0.2	3.9	GO:0071539	protein localization to centrosome(GO:0071539)
0.2	4.3	GO:0019835	cytolysis(GO:0019835)
0.2	5.1	GO:0045747	positive regulation of Notch signaling pathway(GO:0045747)
0.2	9.0	GO:0002181	cytoplasmic translation(GO:0002181)
0.2	3.7	GO:0000245	spliceosomal complex assembly(GO:0000245)
0.2	7.1	GO:0051225	spindle assembly(GO:0051225)
0.2	1.2	GO:0035855	megakaryocyte development(GO:0035855)
0.1	0.4	GO:0061357	positive regulation of Wnt protein secretion(GO:0061357)
0.1	2.7	GO:0031581	hemidesmosome assembly(GO:0031581)
0.1	1.6	GO:0007342	fusion of sperm to egg plasma membrane(GO:0007342)
0.1	5.3	GO:0019882	antigen processing and presentation(GO:0019882)
0.1	1.0	GO:0033591	response to L-ascorbic acid(GO:0033591)
0.1	1.0	GO:0060285	cilium or flagellum-dependent cell motility(GO:0001539) cilium-dependent cell motility(GO:0060285)
0.1	11.4	GO:0007229	integrin-mediated signaling pathway(GO:0007229)
0.1	5.4	GO:0006493	protein O-linked glycosylation(GO:0006493)
0.1	5.0	GO:0007274	neuromuscular synaptic transmission(GO:0007274)
0.1	1.2	GO:0048280	vesicle fusion with Golgi apparatus(GO:0048280)
0.1	4.0	GO:0035825	reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.1	1.4	GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.1	1.6	GO:0034389	lipid particle organization(GO:0034389)
0.1	0.7	GO:0051151	negative regulation of smooth muscle cell differentiation(GO:0051151)
0.1	10.7	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.1	5.7	GO:0045103	intermediate filament-based process(GO:0045103)
0.1	3.3	GO:0036075	endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.1	3.8	GO:0001954	positive regulation of cell-matrix adhesion(GO:0001954)
0.1	6.1	GO:0007040	lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.1	2.0	GO:0006613	cotranslational protein targeting to membrane(GO:0006613)
0.1	0.2	GO:0060382	regulation of DNA strand elongation(GO:0060382)
0.1	3.2	GO:0070527	platelet aggregation(GO:0070527)
0.1	12.8	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.1	0.8	GO:0046882	negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.1	3.2	GO:0032008	positive regulation of TOR signaling(GO:0032008)
0.1	2.3	GO:0060259	regulation of feeding behavior(GO:0060259)
0.1	3.0	GO:1904659	hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.1	1.0	GO:0036315	cellular response to sterol(GO:0036315)
0.1	18.3	GO:0007059	chromosome segregation(GO:0007059)
0.1	0.3	GO:0019730	antimicrobial humoral response(GO:0019730)
0.1	1.1	GO:0034285	response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.1	0.6	GO:1903527	positive regulation of membrane tubulation(GO:1903527)
0.1	0.6	GO:0051096	regulation of helicase activity(GO:0051095) positive regulation of helicase activity(GO:0051096)
0.1	1.3	GO:0043248	proteasome assembly(GO:0043248)
0.1	0.7	GO:0006283	transcription-coupled nucleotide-excision repair(GO:0006283)
0.1	11.2	GO:0006479	protein methylation(GO:0006479) protein alkylation(GO:0008213)
0.1	0.7	GO:0090043	tubulin deacetylation(GO:0090042) regulation of tubulin deacetylation(GO:0090043)
0.1	2.7	GO:0006611	protein export from nucleus(GO:0006611)
0.1	2.1	GO:0048384	retinoic acid receptor signaling pathway(GO:0048384)
0.1	3.0	GO:0032088	negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.1	0.3	GO:0048752	semicircular canal morphogenesis(GO:0048752)
0.1	4.1	GO:0042273	ribosomal large subunit biogenesis(GO:0042273)
0.1	0.7	GO:0046931	pore complex assembly(GO:0046931) nuclear pore complex assembly(GO:0051292)
0.1	1.2	GO:0071108	protein K48-linked deubiquitination(GO:0071108)
0.1	2.7	GO:0043966	histone H3 acetylation(GO:0043966)
0.1	1.1	GO:0034204	lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.1	1.0	GO:0006450	regulation of translational fidelity(GO:0006450)
0.1	6.2	GO:0042113	B cell activation(GO:0042113)
0.1	0.4	GO:0046834	lipid phosphorylation(GO:0046834)
0.0	2.7	GO:0006367	transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0	0.4	GO:0009083	branched-chain amino acid catabolic process(GO:0009083)
0.0	0.3	GO:0090214	spongiotrophoblast layer developmental growth(GO:0090214)
0.0	1.8	GO:0051865	protein autoubiquitination(GO:0051865)
0.0	0.2	GO:0060707	trophoblast giant cell differentiation(GO:0060707)
0.0	0.7	GO:1900003	regulation of serine-type endopeptidase activity(GO:1900003) negative regulation of serine-type endopeptidase activity(GO:1900004) regulation of serine-type peptidase activity(GO:1902571) negative regulation of serine-type peptidase activity(GO:1902572)
0.0	19.6	GO:0000122	negative regulation of transcription from RNA polymerase II promoter(GO:0000122)
0.0	0.8	GO:0010172	embryonic body morphogenesis(GO:0010172)
0.0	2.8	GO:0030901	midbrain development(GO:0030901)
0.0	0.4	GO:0006515	misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.0	1.7	GO:0031338	regulation of vesicle fusion(GO:0031338)
0.0	1.8	GO:0042177	negative regulation of protein catabolic process(GO:0042177)
0.0	0.2	GO:0019370	leukotriene biosynthetic process(GO:0019370)
0.0	0.9	GO:0033138	positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0	0.3	GO:0007195	adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0	0.6	GO:0002279	mast cell activation involved in immune response(GO:0002279) mast cell mediated immunity(GO:0002448) mast cell degranulation(GO:0043303)
0.0	2.5	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.0	1.5	GO:0008645	hexose transport(GO:0008645)
0.0	8.0	GO:0030155	regulation of cell adhesion(GO:0030155)
0.0	0.3	GO:0030970	retrograde protein transport, ER to cytosol(GO:0030970)
0.0	0.6	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0	1.1	GO:0030216	keratinocyte differentiation(GO:0030216)
0.0	0.1	GO:0014886	transition between slow and fast fiber(GO:0014886)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
6.2	24.7	GO:0000444	MIS12/MIND type complex(GO:0000444)
6.2	30.8	GO:0071953	elastic fiber(GO:0071953)
5.4	16.3	GO:0032398	MHC class Ib protein complex(GO:0032398)
5.3	21.1	GO:0019815	B cell receptor complex(GO:0019815)
5.1	25.4	GO:0072558	IPAF inflammasome complex(GO:0072557) NLRP1 inflammasome complex(GO:0072558) AIM2 inflammasome complex(GO:0097169)
5.1	15.2	GO:0030690	Noc1p-Noc2p complex(GO:0030690)
5.0	15.0	GO:0035355	Toll-like receptor 2-Toll-like receptor 6 protein complex(GO:0035355)
4.5	18.1	GO:0031092	platelet alpha granule membrane(GO:0031092)
4.3	13.0	GO:1990826	nucleoplasmic periphery of the nuclear pore complex(GO:1990826)
3.7	14.6	GO:0044299	C-fiber(GO:0044299)
3.5	24.6	GO:0030870	Mre11 complex(GO:0030870)
3.3	16.7	GO:0030015	CCR4-NOT core complex(GO:0030015)
3.2	47.7	GO:1990023	mitotic spindle midzone(GO:1990023)
2.7	43.2	GO:0042613	MHC class II protein complex(GO:0042613)
2.7	10.6	GO:1990630	IRE1-RACK1-PP2A complex(GO:1990630)
2.4	12.2	GO:0034455	t-UTP complex(GO:0034455)
2.3	9.1	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
2.2	6.5	GO:1990682	CSF1-CSF1R complex(GO:1990682)
2.2	6.5	GO:0032807	DNA ligase IV complex(GO:0032807)
2.0	11.7	GO:0035189	Rb-E2F complex(GO:0035189)
1.9	5.8	GO:0035577	azurophil granule membrane(GO:0035577)
1.9	7.6	GO:0020005	symbiont-containing vacuole membrane(GO:0020005)
1.7	10.0	GO:0070419	nonhomologous end joining complex(GO:0070419)
1.6	13.1	GO:0001740	Barr body(GO:0001740)
1.6	4.9	GO:0060187	cell pole(GO:0060187)
1.6	8.1	GO:0044530	supraspliceosomal complex(GO:0044530)
1.5	19.9	GO:0032593	insulin-responsive compartment(GO:0032593)
1.4	17.1	GO:0071564	npBAF complex(GO:0071564)
1.3	5.2	GO:0044307	germinal vesicle(GO:0042585) dendritic branch(GO:0044307)
1.3	5.2	GO:1990005	granular vesicle(GO:1990005)
1.3	5.1	GO:0036156	inner dynein arm(GO:0036156)
1.2	3.7	GO:0071008	U2-type post-mRNA release spliceosomal complex(GO:0071008)
1.2	7.4	GO:0030681	nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
1.2	3.7	GO:1990589	ATF4-CREB1 transcription factor complex(GO:1990589)
1.2	25.7	GO:0019013	viral nucleocapsid(GO:0019013)
1.2	8.5	GO:0036128	CatSper complex(GO:0036128)
1.1	9.6	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
1.0	7.8	GO:0070187	telosome(GO:0070187)
0.9	6.6	GO:0000796	condensin complex(GO:0000796)
0.9	12.2	GO:0000801	central element(GO:0000801)
0.9	4.4	GO:0098536	deuterosome(GO:0098536)
0.8	12.7	GO:0001931	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.8	62.3	GO:0045095	keratin filament(GO:0045095)
0.8	5.8	GO:0097504	Gemini of coiled bodies(GO:0097504)
0.8	16.6	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.8	15.5	GO:0042589	zymogen granule membrane(GO:0042589)
0.8	4.9	GO:0034388	Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.8	12.3	GO:0005685	U1 snRNP(GO:0005685)
0.8	6.8	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.8	11.3	GO:0035102	PRC1 complex(GO:0035102)
0.7	6.8	GO:0043020	NADPH oxidase complex(GO:0043020)
0.6	45.9	GO:0000118	histone deacetylase complex(GO:0000118)
0.6	24.1	GO:0019897	extrinsic component of plasma membrane(GO:0019897)
0.6	57.7	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.6	5.7	GO:0005744	mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.6	4.5	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.6	2.8	GO:1990726	Lsm1-7-Pat1 complex(GO:1990726)
0.6	1.7	GO:0009328	phenylalanine-tRNA ligase complex(GO:0009328)
0.5	181.5	GO:0009897	external side of plasma membrane(GO:0009897)
0.5	4.9	GO:0031390	Ctf18 RFC-like complex(GO:0031390)
0.5	7.4	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.5	2.1	GO:0097524	sperm plasma membrane(GO:0097524)
0.5	5.5	GO:0005686	U2 snRNP(GO:0005686)
0.5	3.3	GO:0061617	MICOS complex(GO:0061617)
0.5	9.3	GO:0000930	gamma-tubulin complex(GO:0000930)
0.5	2.7	GO:0005672	transcription factor TFIIA complex(GO:0005672)
0.5	2.7	GO:0005608	laminin-3 complex(GO:0005608)
0.4	4.7	GO:0005796	Golgi lumen(GO:0005796)
0.4	4.3	GO:0005641	nuclear envelope lumen(GO:0005641)
0.4	4.0	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.4	2.7	GO:0035068	micro-ribonucleoprotein complex(GO:0035068)
0.4	1.9	GO:0002189	ribose phosphate diphosphokinase complex(GO:0002189)
0.4	4.4	GO:0033276	transcription factor TFTC complex(GO:0033276)
0.4	2.2	GO:0071598	neuronal ribonucleoprotein granule(GO:0071598)
0.4	5.7	GO:0005845	mRNA cap binding complex(GO:0005845)
0.3	21.8	GO:0016328	lateral plasma membrane(GO:0016328)
0.3	7.0	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.3	1.9	GO:0032444	activin responsive factor complex(GO:0032444)
0.3	3.7	GO:0042581	specific granule(GO:0042581)
0.3	3.3	GO:0042405	nuclear inclusion body(GO:0042405)
0.3	20.8	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.3	17.1	GO:0000777	condensed chromosome kinetochore(GO:0000777)
0.3	4.5	GO:0005751	mitochondrial respiratory chain complex IV(GO:0005751)
0.3	20.4	GO:0005811	lipid particle(GO:0005811)
0.3	4.0	GO:0030122	AP-2 adaptor complex(GO:0030122)
0.3	7.1	GO:0001772	immunological synapse(GO:0001772)
0.2	7.2	GO:0034451	centriolar satellite(GO:0034451)
0.2	7.8	GO:0009925	basal plasma membrane(GO:0009925)
0.2	0.7	GO:1990836	lysosomal matrix(GO:1990836)
0.2	6.2	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.2	3.9	GO:0097038	perinuclear endoplasmic reticulum(GO:0097038)
0.2	2.4	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.2	14.6	GO:0031225	anchored component of membrane(GO:0031225)
0.2	4.5	GO:0005605	basal lamina(GO:0005605)
0.2	40.9	GO:0009898	cytoplasmic side of plasma membrane(GO:0009898)
0.2	2.3	GO:0044666	MLL3/4 complex(GO:0044666)
0.2	0.7	GO:0034274	Atg12-Atg5-Atg16 complex(GO:0034274)
0.2	4.8	GO:0080008	Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.2	0.8	GO:0035061	interchromatin granule(GO:0035061)
0.2	10.5	GO:0005581	collagen trimer(GO:0005581)
0.2	1.7	GO:0043205	microfibril(GO:0001527) fibril(GO:0043205)
0.1	12.2	GO:0005776	autophagosome(GO:0005776)
0.1	1.0	GO:0000124	SAGA complex(GO:0000124)
0.1	5.7	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.1	1.3	GO:0097539	ciliary transition fiber(GO:0097539)
0.1	2.0	GO:0045334	clathrin-coated endocytic vesicle(GO:0045334)
0.1	1.0	GO:0000275	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.1	4.6	GO:0016235	aggresome(GO:0016235)
0.1	0.9	GO:0005964	phosphorylase kinase complex(GO:0005964)
0.1	8.9	GO:0005902	microvillus(GO:0005902)
0.1	0.3	GO:1990707	subtelomeric heterochromatin(GO:1990421) nuclear subtelomeric heterochromatin(GO:1990707)
0.1	0.6	GO:0071821	FANCM-MHF complex(GO:0071821)
0.1	0.3	GO:0000839	Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.1	0.5	GO:0033588	Elongator holoenzyme complex(GO:0033588)
0.1	3.1	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.1	0.7	GO:0008385	IkappaB kinase complex(GO:0008385)
0.1	0.4	GO:0005947	mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.1	6.8	GO:0071013	catalytic step 2 spliceosome(GO:0071013)
0.1	19.4	GO:0098852	lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.1	3.1	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.1	6.3	GO:0000792	heterochromatin(GO:0000792)
0.1	2.0	GO:0002080	acrosomal membrane(GO:0002080)
0.1	3.2	GO:0031201	SNARE complex(GO:0031201)
0.1	1.3	GO:0000800	lateral element(GO:0000800)
0.1	2.5	GO:0015030	Cajal body(GO:0015030)
0.1	3.1	GO:0005876	spindle microtubule(GO:0005876)
0.1	1.1	GO:0030140	trans-Golgi network transport vesicle(GO:0030140)
0.1	22.1	GO:0005667	transcription factor complex(GO:0005667)
0.1	0.9	GO:0031229	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.1	2.9	GO:0005871	kinesin complex(GO:0005871)
0.1	9.3	GO:0005840	ribosome(GO:0005840)
0.1	1.4	GO:0030992	intraciliary transport particle B(GO:0030992)
0.0	33.6	GO:0005773	vacuole(GO:0005773)
0.0	1.2	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	1.0	GO:0002102	podosome(GO:0002102)
0.0	2.1	GO:0016363	nuclear matrix(GO:0016363)
0.0	2.5	GO:0001669	acrosomal vesicle(GO:0001669)
0.0	1.0	GO:0017053	transcriptional repressor complex(GO:0017053)
0.0	0.5	GO:0001533	cornified envelope(GO:0001533)
0.0	1.8	GO:0001650	fibrillar center(GO:0001650)
0.0	0.2	GO:0032040	small-subunit processome(GO:0032040)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
51.8	155.3	GO:0004556	alpha-amylase activity(GO:0004556)
5.7	46.0	GO:0022840	leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842)
5.5	16.4	GO:0004651	polynucleotide 5'-phosphatase activity(GO:0004651)
5.2	15.7	GO:0019961	interferon binding(GO:0019961)
5.1	25.4	GO:0019770	IgG receptor activity(GO:0019770)
5.1	20.3	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
5.0	15.0	GO:0042498	diacyl lipopeptide binding(GO:0042498)
5.0	30.0	GO:0032027	myosin light chain binding(GO:0032027)
4.9	24.5	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
4.5	18.1	GO:0042806	fucose binding(GO:0042806)
4.5	31.6	GO:0004064	arylesterase activity(GO:0004064)
4.2	21.0	GO:0070892	lipoteichoic acid receptor activity(GO:0070892)
4.2	16.7	GO:0001226	RNA polymerase II transcription corepressor binding(GO:0001226)
3.8	15.2	GO:0035877	death effector domain binding(GO:0035877)
3.6	21.5	GO:0031727	CCR2 chemokine receptor binding(GO:0031727)
3.5	10.4	GO:0016316	phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
3.4	13.6	GO:0030021	extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
3.4	13.4	GO:0004052	arachidonate 12-lipoxygenase activity(GO:0004052)
3.3	13.3	GO:0019767	IgE receptor activity(GO:0019767)
3.2	12.9	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
3.0	9.1	GO:0008281	sulfonylurea receptor activity(GO:0008281)
3.0	23.6	GO:0070087	chromo shadow domain binding(GO:0070087)
2.8	25.4	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
2.8	45.1	GO:0045125	bioactive lipid receptor activity(GO:0045125)
2.7	16.3	GO:0030881	beta-2-microglobulin binding(GO:0030881)
2.6	67.2	GO:0004190	aspartic-type endopeptidase activity(GO:0004190)
2.6	7.8	GO:0001847	opsonin receptor activity(GO:0001847)
2.4	12.2	GO:1990932	5.8S rRNA binding(GO:1990932)
2.4	16.8	GO:0046703	natural killer cell lectin-like receptor binding(GO:0046703)
2.3	11.7	GO:0061676	importin-alpha family protein binding(GO:0061676)
2.3	21.1	GO:0043515	kinetochore binding(GO:0043515)
2.3	21.1	GO:0004716	receptor signaling protein tyrosine kinase activity(GO:0004716)
2.2	18.0	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
2.1	20.8	GO:0098505	G-rich strand telomeric DNA binding(GO:0098505)
2.1	10.3	GO:0004974	leukotriene receptor activity(GO:0004974)
2.1	26.7	GO:1990405	protein antigen binding(GO:1990405)
2.0	46.9	GO:0051861	glycolipid binding(GO:0051861)
1.9	5.8	GO:0004084	branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
1.9	7.6	GO:0019002	GMP binding(GO:0019002)
1.9	13.1	GO:0035375	zymogen binding(GO:0035375)
1.9	20.5	GO:0016493	C-C chemokine receptor activity(GO:0016493)
1.8	5.5	GO:0030620	U2 snRNA binding(GO:0030620)
1.8	8.8	GO:0050309	glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
1.6	13.2	GO:0001164	RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
1.6	14.7	GO:0004875	complement receptor activity(GO:0004875)
1.6	11.3	GO:0070181	small ribosomal subunit rRNA binding(GO:0070181)
1.5	6.2	GO:0005134	interleukin-2 receptor binding(GO:0005134)
1.5	16.9	GO:0000014	single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
1.4	4.3	GO:0004051	arachidonate 5-lipoxygenase activity(GO:0004051)
1.4	38.2	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
1.4	15.4	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
1.4	19.2	GO:0042043	neurexin family protein binding(GO:0042043)
1.3	10.6	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
1.3	11.8	GO:1990446	U1 snRNA binding(GO:0030619) U1 snRNP binding(GO:1990446)
1.3	9.0	GO:0035252	UDP-xylosyltransferase activity(GO:0035252)
1.3	96.6	GO:0003823	antigen binding(GO:0003823)
1.3	6.3	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
1.2	3.7	GO:1990763	arrestin family protein binding(GO:1990763)
1.2	3.5	GO:0003921	GMP synthase activity(GO:0003921) GMP synthase (glutamine-hydrolyzing) activity(GO:0003922)
1.1	6.8	GO:0034647	histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
1.1	12.8	GO:0019869	chloride channel inhibitor activity(GO:0019869)
1.1	5.3	GO:0043262	adenosine-diphosphatase activity(GO:0043262)
1.0	14.3	GO:0003688	DNA replication origin binding(GO:0003688)
0.9	15.1	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.9	16.6	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.9	4.5	GO:0009019	tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.9	4.5	GO:0001054	RNA polymerase I activity(GO:0001054)
0.9	4.3	GO:0043682	copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682)
0.9	128.1	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.9	2.6	GO:0004605	phosphatidate cytidylyltransferase activity(GO:0004605)
0.8	7.5	GO:0008559	xenobiotic-transporting ATPase activity(GO:0008559)
0.8	8.9	GO:0008131	primary amine oxidase activity(GO:0008131)
0.8	2.4	GO:0089720	caspase binding(GO:0089720)
0.8	9.5	GO:0001608	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.8	6.1	GO:0004630	phospholipase D activity(GO:0004630)
0.8	2.3	GO:0004832	valine-tRNA ligase activity(GO:0004832)
0.8	2.3	GO:0004574	oligo-1,6-glucosidase activity(GO:0004574)
0.8	6.0	GO:0001055	RNA polymerase II activity(GO:0001055)
0.7	18.7	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.7	7.4	GO:0004526	ribonuclease P activity(GO:0004526)
0.7	3.7	GO:0008745	N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.7	17.7	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
0.7	6.5	GO:0003909	DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.7	218.2	GO:0030246	carbohydrate binding(GO:0030246)
0.7	21.5	GO:0031492	nucleosomal DNA binding(GO:0031492)
0.7	2.1	GO:0005171	hepatocyte growth factor receptor binding(GO:0005171)
0.7	6.8	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.7	37.8	GO:0005507	copper ion binding(GO:0005507)
0.7	2.6	GO:0031731	CCR6 chemokine receptor binding(GO:0031731)
0.6	5.7	GO:0015450	protein channel activity(GO:0015266) P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.6	9.4	GO:0009982	pseudouridine synthase activity(GO:0009982)
0.6	12.4	GO:0017127	cholesterol transporter activity(GO:0017127)
0.6	31.5	GO:0001786	phosphatidylserine binding(GO:0001786)
0.6	13.9	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.6	12.1	GO:0015106	bicarbonate transmembrane transporter activity(GO:0015106)
0.6	2.9	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.6	2.3	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.6	11.2	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.6	15.6	GO:0042169	SH2 domain binding(GO:0042169)
0.6	2.2	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
0.6	6.7	GO:0005451	monovalent cation:proton antiporter activity(GO:0005451)
0.6	3.3	GO:0061578	Lys63-specific deubiquitinase activity(GO:0061578)
0.6	9.4	GO:0097602	cullin family protein binding(GO:0097602)
0.5	8.7	GO:0019843	rRNA binding(GO:0019843)
0.5	4.3	GO:0008479	queuine tRNA-ribosyltransferase activity(GO:0008479)
0.5	3.2	GO:0000099	sulfur amino acid transmembrane transporter activity(GO:0000099)
0.5	2.0	GO:0004487	methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.5	4.0	GO:0047134	protein-disulfide reductase activity(GO:0047134)
0.5	4.5	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
0.5	208.8	GO:0005525	GTP binding(GO:0005525)
0.5	12.2	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.5	2.4	GO:0008823	cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.5	4.3	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.5	3.3	GO:0004065	arylsulfatase activity(GO:0004065)
0.5	1.9	GO:0043199	sulfate binding(GO:0043199)
0.5	2.8	GO:0015189	L-lysine transmembrane transporter activity(GO:0015189)
0.5	5.1	GO:0042609	CD4 receptor binding(GO:0042609)
0.5	48.7	GO:0005178	integrin binding(GO:0005178)
0.5	17.4	GO:0001784	phosphotyrosine binding(GO:0001784)
0.4	13.6	GO:0030515	snoRNA binding(GO:0030515)
0.4	11.1	GO:0001106	RNA polymerase II transcription corepressor activity(GO:0001106)
0.4	2.5	GO:0008970	phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.4	8.8	GO:0032183	SUMO binding(GO:0032183)
0.4	11.1	GO:0004129	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.4	4.4	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.3	19.9	GO:0035064	methylated histone binding(GO:0035064)
0.3	7.1	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.3	24.1	GO:0033613	activating transcription factor binding(GO:0033613)
0.3	4.2	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.3	78.8	GO:0003735	structural constituent of ribosome(GO:0003735)
0.3	11.8	GO:0004712	protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.3	1.9	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
0.3	3.0	GO:0005412	glucose:sodium symporter activity(GO:0005412)
0.3	4.5	GO:0008409	5'-3' exonuclease activity(GO:0008409)
0.3	8.7	GO:0003785	actin monomer binding(GO:0003785)
0.3	34.9	GO:0042393	histone binding(GO:0042393)
0.3	26.4	GO:0004540	ribonuclease activity(GO:0004540)
0.3	1.7	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.3	15.0	GO:0003743	translation initiation factor activity(GO:0003743)
0.3	2.1	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.3	5.2	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.3	30.0	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.2	4.0	GO:0016864	protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.2	1.4	GO:0048039	ubiquinone binding(GO:0048039)
0.2	0.4	GO:0031852	mu-type opioid receptor binding(GO:0031852)
0.2	1.7	GO:0035612	AP-2 adaptor complex binding(GO:0035612)
0.2	4.8	GO:0070840	dynein complex binding(GO:0070840)
0.2	15.0	GO:0016209	antioxidant activity(GO:0016209)
0.2	1.0	GO:0043532	angiostatin binding(GO:0043532)
0.2	7.0	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.2	1.5	GO:0017151	DEAD/H-box RNA helicase binding(GO:0017151)
0.2	0.7	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.2	4.0	GO:0042162	telomeric DNA binding(GO:0042162)
0.2	1.5	GO:0031078	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.2	0.7	GO:0019776	Atg8 ligase activity(GO:0019776)
0.2	5.7	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631)
0.2	1.6	GO:0086080	protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.2	13.9	GO:0004896	cytokine receptor activity(GO:0004896)
0.2	2.8	GO:0017160	Ral GTPase binding(GO:0017160)
0.2	1.6	GO:0008641	small protein activating enzyme activity(GO:0008641)
0.2	16.0	GO:0017124	SH3 domain binding(GO:0017124)
0.2	0.8	GO:0048185	activin binding(GO:0048185)
0.1	2.8	GO:0000993	RNA polymerase II core binding(GO:0000993)
0.1	5.3	GO:0005080	protein kinase C binding(GO:0005080)
0.1	9.0	GO:0003777	microtubule motor activity(GO:0003777)
0.1	10.9	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity(GO:0036459)
0.1	2.7	GO:0001103	RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1	5.6	GO:0032813	tumor necrosis factor receptor superfamily binding(GO:0032813)
0.1	0.9	GO:0004689	phosphorylase kinase activity(GO:0004689)
0.1	4.3	GO:0005160	transforming growth factor beta receptor binding(GO:0005160)
0.1	5.6	GO:0019955	cytokine binding(GO:0019955)
0.1	2.7	GO:0008536	Ran GTPase binding(GO:0008536)
0.1	1.3	GO:0016805	dipeptidase activity(GO:0016805)
0.1	26.0	GO:0001077	transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.1	1.9	GO:0000146	microfilament motor activity(GO:0000146)
0.1	1.1	GO:0015379	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1	1.0	GO:0002161	aminoacyl-tRNA editing activity(GO:0002161)
0.1	0.4	GO:0001729	ceramide kinase activity(GO:0001729)
0.1	5.8	GO:0003697	single-stranded DNA binding(GO:0003697)
0.1	2.3	GO:0071855	neuropeptide receptor binding(GO:0071855)
0.1	1.1	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.1	13.5	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.1	3.3	GO:0003725	double-stranded RNA binding(GO:0003725)
0.0	4.1	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553)
0.0	1.4	GO:0030331	estrogen receptor binding(GO:0030331)
0.0	0.2	GO:0036374	gamma-glutamyltransferase activity(GO:0003840) glutathione hydrolase activity(GO:0036374)
0.0	0.8	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0	0.3	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0	1.4	GO:0097110	scaffold protein binding(GO:0097110)
0.0	0.5	GO:0001594	trace-amine receptor activity(GO:0001594)
0.0	0.6	GO:0043015	gamma-tubulin binding(GO:0043015)
0.0	0.6	GO:0042923	neuropeptide binding(GO:0042923)
0.0	1.5	GO:0051287	NAD binding(GO:0051287)
0.0	0.9	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.2	58.0	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
1.7	5.2	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
1.4	63.5	PID ARF6 PATHWAY	Arf6 signaling events
1.4	15.2	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
1.2	16.6	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
1.2	18.9	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
1.1	21.7	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
1.1	8.6	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.9	34.5	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.8	13.2	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.6	14.9	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.6	14.6	PID GMCSF PATHWAY	GMCSF-mediated signaling events
0.6	7.8	PID IL5 PATHWAY	IL5-mediated signaling events
0.6	7.8	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.6	46.7	PID RB 1PATHWAY	Regulation of retinoblastoma protein
0.6	5.8	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.5	14.3	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.5	4.8	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.5	1.1	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.5	10.1	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.5	18.1	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
0.5	11.5	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.5	12.7	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.5	14.9	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.5	8.1	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.4	19.7	ST FAS SIGNALING PATHWAY	Fas Signaling Pathway
0.4	6.5	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.4	24.8	PID TELOMERASE PATHWAY	Regulation of Telomerase
0.4	18.7	PID PLK1 PATHWAY	PLK1 signaling events
0.4	6.5	PID PTP1B PATHWAY	Signaling events mediated by PTP1B
0.4	21.1	PID REG GR PATHWAY	Glucocorticoid receptor regulatory network
0.4	17.6	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.4	11.0	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.4	42.7	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
0.4	11.7	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.4	84.2	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.4	20.7	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.3	7.1	PID REELIN PATHWAY	Reelin signaling pathway
0.3	12.9	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.3	59.2	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.3	5.9	PID BARD1 PATHWAY	BARD1 signaling events
0.3	4.8	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.2	3.9	PID MYC PATHWAY	C-MYC pathway
0.2	4.2	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.2	6.9	PID IL12 2PATHWAY	IL12-mediated signaling events
0.2	7.5	PID IL4 2PATHWAY	IL4-mediated signaling events
0.2	3.8	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.2	2.3	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.2	2.3	PID IL23 PATHWAY	IL23-mediated signaling events
0.2	1.8	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.2	3.9	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
0.2	1.2	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.2	8.1	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
0.2	2.8	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.2	2.8	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.1	6.3	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.1	6.0	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
0.1	0.5	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
0.1	0.9	ST GAQ PATHWAY	G alpha q Pathway
0.1	1.8	PID FANCONI PATHWAY	Fanconi anemia pathway
0.0	0.6	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.0	0.7	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.0	0.5	PID RAC1 PATHWAY	RAC1 signaling pathway
0.0	0.3	PID AURORA B PATHWAY	Aurora B signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.8	15.0	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
2.1	25.4	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
1.9	97.4	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
1.9	26.7	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
1.7	18.3	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
1.6	19.8	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
1.4	15.2	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
1.4	6.9	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
1.3	6.6	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
1.3	27.6	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
1.2	11.7	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
1.0	21.4	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
1.0	7.8	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.8	20.0	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.8	28.8	REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX	Genes involved in Activation of the pre-replicative complex
0.8	10.3	REACTOME EICOSANOID LIGAND BINDING RECEPTORS	Genes involved in Eicosanoid ligand-binding receptors
0.8	19.1	REACTOME ANTIGEN PROCESSING CROSS PRESENTATION	Genes involved in Antigen processing-Cross presentation
0.7	6.5	REACTOME INTEGRATION OF PROVIRUS	Genes involved in Integration of provirus
0.7	16.7	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.7	25.6	REACTOME AMINE COMPOUND SLC TRANSPORTERS	Genes involved in Amine compound SLC transporters
0.6	15.0	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.6	13.5	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.5	13.5	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.5	36.1	REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1	Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.5	14.6	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.5	13.1	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.5	4.5	REACTOME RNA POL I TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase I Transcription Termination
0.5	55.8	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.4	18.3	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.4	7.0	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.4	16.6	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.4	40.4	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.4	10.3	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
0.4	3.2	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.4	7.1	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.4	2.3	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
0.4	1.5	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.3	16.1	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
0.3	31.2	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.3	3.7	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII	Genes involved in CREB phosphorylation through the activation of CaMKII
0.3	16.8	REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS	Genes involved in Phase 1 - Functionalization of compounds
0.3	8.5	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.3	3.3	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.3	7.8	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.3	5.8	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.3	2.7	REACTOME REGULATORY RNA PATHWAYS	Genes involved in Regulatory RNA pathways
0.3	3.5	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.3	7.1	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.2	17.9	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.2	5.0	REACTOME MEIOSIS	Genes involved in Meiosis
0.2	3.8	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.2	1.1	REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX	Genes involved in TRAF6 mediated induction of TAK1 complex
0.1	2.8	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.1	4.1	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.1	6.7	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.1	6.4	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.1	3.6	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.1	1.0	REACTOME REGULATION OF APOPTOSIS	Genes involved in Regulation of Apoptosis
0.1	8.6	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.1	1.7	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.1	4.5	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1	1.5	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.1	2.0	REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE	Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.1	2.2	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.1	1.9	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.1	2.5	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1	0.9	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.1	2.2	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.1	2.6	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.1	0.3	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.1	4.1	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	1.5	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	0.6	REACTOME SIGNAL TRANSDUCTION BY L1	Genes involved in Signal transduction by L1
0.0	0.3	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	0.5	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling

Results for Dlx1

Z-value: 1.48

Motif logo

Transcription factors associated with Dlx1

Activity-expression correlation:

Activity profile of Dlx1 motif

Sorted Z-values of Dlx1 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of Dlx1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: