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GSE49485: Hypoxia transcriptome sequencing of rat brain.
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Results for Prdm1
Z-value: 0.91
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Transcription factors associated with Prdm1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Prdm1 | rn6_v1_chr20_-_49486550_49486552 | -0.97 | 6.0e-03 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr3_+_177397892 Show fit | 0.53 |
ENSRNOT00000078261
|
|
|
| chr12_-_17186679 Show fit | 0.52 |
ENSRNOT00000001730
|
UNC homeobox |
|
| chr5_+_161889342 Show fit | 0.33 |
ENSRNOT00000040481
|
ribosomal protein S20-like |
|
| chr9_-_1012450 Show fit | 0.33 |
ENSRNOT00000051449
|
ribosomal protein S20-like |
|
| chr7_+_124460358 Show fit | 0.31 |
ENSRNOT00000014089
|
translocator protein |
|
| chr5_-_16706909 Show fit | 0.31 |
ENSRNOT00000011314
|
ribosomal protein S20 |
|
| chr13_+_89480058 Show fit | 0.30 |
ENSRNOT00000050804
|
cilia and flagella associated protein 126 |
|
| chr3_-_7498555 Show fit | 0.30 |
ENSRNOT00000017725
|
BarH-like homeobox 1 |
|
| chr20_+_8484311 Show fit | 0.29 |
ENSRNOT00000050041
|
ribosomal protein S20-like |
|
| chr2_+_29598344 Show fit | 0.28 |
ENSRNOT00000088580
ENSRNOT00000023286 |
mitochondrial ribosomal protein S27 |
Network of associatons between targets according to the STRING database.
First level regulatory network of Prdm1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.5 | GO:0035726 | common myeloid progenitor cell proliferation(GO:0035726) |
| 0.1 | 0.3 | GO:0045629 | negative regulation of T-helper 2 cell differentiation(GO:0045629) |
| 0.1 | 0.3 | GO:0010266 | response to vitamin B1(GO:0010266) maintenance of protein location in mitochondrion(GO:0072656) |
| 0.0 | 0.3 | GO:0045475 | locomotor rhythm(GO:0045475) |
| 0.0 | 0.3 | GO:1900027 | regulation of ruffle assembly(GO:1900027) |
| 0.1 | 0.2 | GO:1901492 | positive regulation of lymphangiogenesis(GO:1901492) |
| 0.1 | 0.2 | GO:0035425 | autocrine signaling(GO:0035425) |
| 0.0 | 0.2 | GO:2000195 | negative regulation of female gonad development(GO:2000195) |
| 0.0 | 0.2 | GO:0021759 | globus pallidus development(GO:0021759) Clara cell differentiation(GO:0060486) |
| 0.0 | 0.2 | GO:0030421 | defecation(GO:0030421) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.3 | GO:1990111 | spermatoproteasome complex(GO:1990111) |
| 0.0 | 0.3 | GO:0016272 | prefoldin complex(GO:0016272) |
| 0.0 | 0.3 | GO:0000940 | condensed chromosome outer kinetochore(GO:0000940) |
| 0.1 | 0.2 | GO:0032173 | septin collar(GO:0032173) |
| 0.0 | 0.2 | GO:0033269 | internode region of axon(GO:0033269) |
| 0.0 | 0.2 | GO:0002080 | acrosomal membrane(GO:0002080) |
| 0.0 | 0.1 | GO:0008537 | proteasome activator complex(GO:0008537) |
| 0.0 | 0.1 | GO:1990622 | CHOP-ATF3 complex(GO:1990622) |
| 0.0 | 0.1 | GO:0034388 | Pwp2p-containing subcomplex of 90S preribosome(GO:0034388) |
| 0.0 | 0.1 | GO:0034715 | pICln-Sm protein complex(GO:0034715) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.4 | GO:0070003 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
| 0.0 | 0.2 | GO:0008970 | phosphatidylcholine 1-acylhydrolase activity(GO:0008970) |
| 0.0 | 0.2 | GO:0008503 | benzodiazepine receptor activity(GO:0008503) |
| 0.0 | 0.2 | GO:0008428 | ribonuclease inhibitor activity(GO:0008428) |
| 0.0 | 0.2 | GO:0001161 | intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) |
| 0.0 | 0.2 | GO:0005172 | vascular endothelial growth factor receptor binding(GO:0005172) |
| 0.0 | 0.2 | GO:0010314 | phosphatidylinositol-5-phosphate binding(GO:0010314) |
| 0.0 | 0.2 | GO:0005242 | inward rectifier potassium channel activity(GO:0005242) |
| 0.0 | 0.1 | GO:0004478 | methionine adenosyltransferase activity(GO:0004478) |
| 0.0 | 0.1 | GO:0004574 | oligo-1,6-glucosidase activity(GO:0004574) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.2 | PID VEGF VEGFR PATHWAY | VEGF and VEGFR signaling network |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.5 | REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES | Genes involved in Cross-presentation of soluble exogenous antigens (endosomes) |
| 0.0 | 0.2 | REACTOME VEGF LIGAND RECEPTOR INTERACTIONS | Genes involved in VEGF ligand-receptor interactions |