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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Nfic_Nfib

Z-value: 0.78

Motif logo

Transcription factors associated with Nfic_Nfib

Gene Symbol Gene ID Gene Info
ENSRNOG00000004505 nuclear factor I/C
ENSRNOG00000009795 nuclear factor I/B

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nfibrn6_v1_chr5_-_100647298_100647298-0.424.8e-01Click!
Nficrn6_v1_chr7_+_11152038_111520380.424.8e-01Click!

Activity profile of Nfic_Nfib motif

Sorted Z-values of Nfic_Nfib motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_80416273 1.21 ENSRNOT00000023457
biogenesis of lysosomal organelles complex-1, subunit 3
chr4_-_147163467 0.68 ENSRNOT00000010748
tissue inhibitor of metalloproteinase 4
chr15_-_34550850 0.66 ENSRNOT00000027794
ENSRNOT00000090228
cerebellin 3 precursor
chr4_+_8256611 0.58 ENSRNOT00000061894

chr5_+_154522119 0.56 ENSRNOT00000072618
E2F transcription factor 2
chr20_+_5008508 0.55 ENSRNOT00000001153
von Willebrand factor A domain containing 7
chr14_+_83724933 0.47 ENSRNOT00000029848
phospholipase A2, group III
chr20_-_9855443 0.47 ENSRNOT00000090275
ENSRNOT00000066266
trefoil factor 3
chrX_-_23187341 0.46 ENSRNOT00000000180
5'-aminolevulinate synthase 2
chr4_+_7377563 0.45 ENSRNOT00000084826
potassium voltage-gated channel subfamily H member 2
chr15_-_27815261 0.43 ENSRNOT00000032992
kelch-like family member 33
chr5_-_134526089 0.42 ENSRNOT00000013321
cytochrome P450, family 4, subfamily b, polypeptide 1
chr7_-_119441487 0.37 ENSRNOT00000067635
parvalbumin
chr4_+_169161585 0.36 ENSRNOT00000079785
epithelial membrane protein 1
chr16_+_54291251 0.35 ENSRNOT00000079006
microtubule associated tumor suppressor 1
chr19_+_55669626 0.34 ENSRNOT00000033352
cadherin 15
chr1_-_124803363 0.33 ENSRNOT00000066380
Kruppel-like factor 13
chr2_-_195888216 0.31 ENSRNOT00000056436
tuftelin 1
chr4_-_85386231 0.30 ENSRNOT00000015316
indolethylamine N-methyltransferase
chr17_+_6909728 0.30 ENSRNOT00000061231
hypothetical protein LOC681410
chr10_+_56662242 0.30 ENSRNOT00000086919
asialoglycoprotein receptor 1
chr5_-_156734541 0.30 ENSRNOT00000021036
cytidine deaminase-like
chr7_-_12609694 0.30 ENSRNOT00000093287
ENSRNOT00000079485
KISS1 receptor
chr1_+_147021436 0.28 ENSRNOT00000042490
coagulation factor VIII-associated 1
chr14_+_84237520 0.27 ENSRNOT00000083580
galactose-3-O-sulfotransferase 1
chr4_+_169147243 0.26 ENSRNOT00000011580
epithelial membrane protein 1
chr17_-_61332391 0.26 ENSRNOT00000034599
SNRPN upstream reading frame protein-like
chr7_+_116632506 0.26 ENSRNOT00000009811
glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1
chr18_+_79406381 0.26 ENSRNOT00000022303
ENSRNOT00000058295
ENSRNOT00000058296
ENSRNOT00000022280
myelin basic protein
chr2_-_195908037 0.24 ENSRNOT00000079776
tuftelin 1
chr5_+_136669674 0.23 ENSRNOT00000048770
solute carrier family 6 member 9
chr4_-_100232559 0.22 ENSRNOT00000016984
vesicle-associated membrane protein 5
chr11_+_31002451 0.21 ENSRNOT00000002838
eva-1 homolog C
chr17_+_80882666 0.21 ENSRNOT00000024430
vimentin
chr9_+_117795132 0.21 ENSRNOT00000086943
A-kinase anchor inhibitor 1
chr10_-_104681377 0.21 ENSRNOT00000046026
tripartite motif-containing 65
chr2_+_95320283 0.20 ENSRNOT00000015537
hes-related family bHLH transcription factor with YRPW motif 1
chr10_-_104163634 0.20 ENSRNOT00000005198
MIF4G domain containing
chr1_-_89543967 0.19 ENSRNOT00000079631
hepsin
chr8_-_117932518 0.19 ENSRNOT00000028130
cathelicidin antimicrobial peptide
chr5_-_138697641 0.18 ENSRNOT00000012062
guanylate cyclase activator 2B
chr10_-_45534570 0.18 ENSRNOT00000058362
gap junction protein, gamma 2
chr4_+_62220736 0.18 ENSRNOT00000086377
caldesmon 1
chr3_+_14467330 0.17 ENSRNOT00000078939
gelsolin
chr10_+_49231730 0.16 ENSRNOT00000065335
tripartite motif-containing 16
chr1_+_221792221 0.16 ENSRNOT00000054828
neurexin 2
chr10_-_15166457 0.16 ENSRNOT00000026676
meteorin, glial cell differentiation regulator
chr4_-_123494742 0.15 ENSRNOT00000073268
solute carrier family 41, member 3
chr2_+_266141581 0.15 ENSRNOT00000078187
ENSRNOT00000051951
RPE65, retinoid isomerohydrolase
chr13_+_47454591 0.15 ENSRNOT00000005791
similar to specifically androgen-regulated protein
chr5_-_12526962 0.15 ENSRNOT00000092104
suppression of tumorigenicity 18
chr9_+_50526811 0.14 ENSRNOT00000036990
similar to RIKEN cDNA 1500015O10
chrX_-_106558366 0.14 ENSRNOT00000042126
brain expressed X-linked 2
chr3_-_160853650 0.14 ENSRNOT00000018844
matrilin 4
chr1_-_221281180 0.14 ENSRNOT00000028379
CDC42 effector protein 2
chr3_-_2689084 0.13 ENSRNOT00000020926
prostaglandin D2 synthase
chr12_+_24978483 0.13 ENSRNOT00000040069
elastin
chr10_-_62648844 0.13 ENSRNOT00000034282
abhydrolase domain containing 15
chr13_+_89524329 0.13 ENSRNOT00000004279
myelin protein zero
chr8_-_45375435 0.13 ENSRNOT00000010873
ubiquitin associated and SH3 domain containing, B
chr15_-_60289763 0.13 ENSRNOT00000038579
family with sequence similarity 216, member B
chr3_-_153188915 0.13 ENSRNOT00000079893
suppressor of glucose, autophagy associated 1
chr5_-_155772040 0.13 ENSRNOT00000036788
chymotrypsin-like elastase family, member 3B
chr9_+_73493027 0.12 ENSRNOT00000074427
ENSRNOT00000089478
unc-80 homolog, NALCN activator
chr5_+_162031722 0.12 ENSRNOT00000020483
leucine rich repeat containing 38
chr11_-_39448503 0.12 ENSRNOT00000047347
SH3 domain-binding glutamic acid-rich protein-like
chr1_-_188713270 0.12 ENSRNOT00000082192
ENSRNOT00000065892
G protein-coupled receptor, class C, group 5, member B
chr3_-_8766433 0.12 ENSRNOT00000021865
kynurenine aminotransferase 1
chr10_-_104575890 0.12 ENSRNOT00000050223
H3 histone family member 3B
chr16_-_74122889 0.12 ENSRNOT00000025763
plasminogen activator, tissue type
chr6_+_107245820 0.11 ENSRNOT00000012757
papilin, proteoglycan-like sulfated glycoprotein
chr14_-_8510138 0.11 ENSRNOT00000080758
Rho GTPase activating protein 24
chr1_+_219764001 0.11 ENSRNOT00000082388
pyruvate carboxylase
chr5_+_135029955 0.11 ENSRNOT00000074860
uncharacterized LOC100911669
chr18_+_70263359 0.11 ENSRNOT00000019573
cilia and flagella associated protein 53
chr3_+_63510293 0.11 ENSRNOT00000058093
deafness, autosomal recessive 59
chr5_-_160620334 0.10 ENSRNOT00000019171
transmembrane protein 51
chr9_-_80167033 0.10 ENSRNOT00000023530
insulin-like growth factor binding protein 5
chr20_+_13778178 0.10 ENSRNOT00000058314
glutathione S-transferase, theta 4
chr7_+_130296897 0.10 ENSRNOT00000044854
adrenomedullin 2
chr6_-_111222858 0.10 ENSRNOT00000074707
transmembrane p24 trafficking protein 8
chr12_+_50407843 0.10 ENSRNOT00000073763
crystallin, beta A4
chr18_+_32273770 0.10 ENSRNOT00000087408
fibroblast growth factor 1
chr3_+_109862117 0.10 ENSRNOT00000083351
ENSRNOT00000070912
thrombospondin 1
chr4_+_145427367 0.10 ENSRNOT00000037788
interleukin 17 receptor C
chr1_+_89162639 0.10 ENSRNOT00000028508
ATPase H+/K+ transporting alpha subunit
chr13_-_50497466 0.10 ENSRNOT00000076072
ethanolamine kinase 2
chr2_+_225827504 0.10 ENSRNOT00000018343
glutamate cysteine ligase, modifier subunit
chr1_-_91042230 0.10 ENSRNOT00000073107
DNA-directed RNA polymerase II subunit RPB9
chr1_+_221099998 0.10 ENSRNOT00000028262
latent transforming growth factor beta binding protein 3
chr9_+_98668231 0.10 ENSRNOT00000027528
ankyrin repeat and SOCS box-containing 1
chr4_+_117962319 0.10 ENSRNOT00000057441
transforming growth factor alpha
chr7_-_144993652 0.10 ENSRNOT00000087748
integrin subunit alpha 5
chr3_+_172195844 0.09 ENSRNOT00000034915
aminopeptidase-like 1
chr10_-_90999506 0.09 ENSRNOT00000034401
glial fibrillary acidic protein
chrX_+_63343546 0.09 ENSRNOT00000076315
kelch-like family member 15
chr10_+_13836128 0.09 ENSRNOT00000012720
phosphoglycolate phosphatase
chr1_+_154606490 0.09 ENSRNOT00000024095
coiled-coil domain containing 89
chr3_+_3788583 0.09 ENSRNOT00000084567
G-protein signaling modulator 1
chr8_-_130429132 0.09 ENSRNOT00000026261
hedgehog acyltransferase-like
chr8_+_116096458 0.09 ENSRNOT00000021188
similar to RIKEN cDNA 6430571L13 gene; similar to g20 protein
chr5_+_59008933 0.09 ENSRNOT00000023060
carbonic anhydrase 9
chr4_-_148845267 0.09 ENSRNOT00000037397
transmembrane protein 72
chr3_-_3574787 0.09 ENSRNOT00000087651
NACC family member 2
chr8_+_95968652 0.08 ENSRNOT00000015057
5' nucleotidase, ecto
chr1_+_86938138 0.08 ENSRNOT00000075601
coiled-coil glutamate-rich protein 2
chr1_-_101514547 0.08 ENSRNOT00000079633
protein phosphatase 1, regulatory subunit 15A
chr17_-_32558180 0.08 ENSRNOT00000022681
serine (or cysteine) peptidase inhibitor, clade B, member 1b
chr7_-_15225309 0.08 ENSRNOT00000075589
ENSRNOT00000066095
cytochrome P450, family 4, subfamily f, polypeptide 6
chr1_-_156327352 0.08 ENSRNOT00000074282
coiled-coil domain-containing protein 89-like
chr1_+_89008117 0.08 ENSRNOT00000028401
heat shock protein family B (small) member 6
chrX_+_106823491 0.08 ENSRNOT00000045997
brain expressed X-linked 3
chr14_+_80403001 0.08 ENSRNOT00000012109
carboxypeptidase Z
chr15_-_52210746 0.08 ENSRNOT00000046054
bone morphogenetic protein 1
chr2_+_226900619 0.08 ENSRNOT00000019638
phosphodiesterase 5A
chr2_-_187854363 0.08 ENSRNOT00000092993
lamin A/C
chr18_-_25997555 0.08 ENSRNOT00000027755
StAR-related lipid transfer domain containing 4
chr6_-_45669148 0.08 ENSRNOT00000010092
radical S-adenosyl methionine domain containing 2
chr5_-_144345531 0.08 ENSRNOT00000014721
tektin 2
chr3_+_11679530 0.08 ENSRNOT00000074562
ENSRNOT00000071801
endoglin
chr9_-_9985630 0.08 ENSRNOT00000071780
crumbs 3, cell polarity complex component
chr12_-_21761487 0.08 ENSRNOT00000082910
TSC22 domain family protein 4-like
chr15_+_28287024 0.08 ENSRNOT00000064907
methyltransferase like 17
chr4_+_55720010 0.08 ENSRNOT00000063987
fascin actin-bundling protein 3
chr13_+_89919667 0.07 ENSRNOT00000006196
intelectin 1
chr1_+_12823363 0.07 ENSRNOT00000086790
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
chr17_-_70548071 0.07 ENSRNOT00000073144
interleukin 2 receptor subunit alpha
chr1_-_142020525 0.07 ENSRNOT00000042558
calcium and integrin binding 1
chr1_-_162385575 0.07 ENSRNOT00000016540
thyroid hormone responsive
chr10_-_18942540 0.07 ENSRNOT00000007187
potassium voltage-gated channel interacting protein 1
chr14_+_10534423 0.07 ENSRNOT00000002983
heparanase
chr9_+_10941613 0.07 ENSRNOT00000070794
semaphorin 6B
chr14_+_46001849 0.07 ENSRNOT00000076611
RELT-like 1
chr7_-_70842405 0.07 ENSRNOT00000047449
neurexophilin 4
chr13_+_90723092 0.07 ENSRNOT00000010146
ATP-sensitive inward rectifier potassium channel 10
chr5_-_58950373 0.07 ENSRNOT00000060442
Cd72 molecule
chr1_+_219833299 0.06 ENSRNOT00000087432
pyruvate carboxylase
chr10_+_58875826 0.06 ENSRNOT00000020071
F-box protein 39
chr13_+_89622632 0.06 ENSRNOT00000004713
ADAM metallopeptidase with thrombospondin type 1 motif, 4
chr5_-_126395668 0.06 ENSRNOT00000010396
acyl-CoA thioesterase 11
chr8_+_64481172 0.06 ENSRNOT00000015332
pyruvate kinase, muscle
chr7_+_120465130 0.06 ENSRNOT00000016077
protein interacting with PRKCA 1
chr9_+_81655629 0.06 ENSRNOT00000088679
ENSRNOT00000057472
solute carrier family 11 member 1
chr2_+_233615739 0.06 ENSRNOT00000051009
paired-like homeodomain 2
chr7_+_18409147 0.06 ENSRNOT00000086336
ENSRNOT00000011849
ADAM metallopeptidase with thrombospondin type 1 motif, 10
chr20_-_2224463 0.06 ENSRNOT00000001019
tripartite motif-containing 26
chr12_+_22449985 0.06 ENSRNOT00000075951
solute carrier family 12, member 9
chr1_+_226993250 0.06 ENSRNOT00000054808
prostaglandin D2 receptor 2
chr4_+_144382945 0.06 ENSRNOT00000007601
caveolin 3
chr10_+_17486579 0.06 ENSRNOT00000080404
serine/threonine kinase 10
chr16_+_21282467 0.06 ENSRNOT00000065345
YjeF N-terminal domain containing 3
chr5_-_156781291 0.06 ENSRNOT00000075128
cytidine deaminase
chr13_+_112031594 0.06 ENSRNOT00000008440
laminin subunit beta 3
chr3_-_151224123 0.05 ENSRNOT00000026091
transient receptor potential cation channel, subfamily C, member 4 associated protein
chrX_+_33895769 0.05 ENSRNOT00000085993
ENSRNOT00000079365
RALBP1 associated Eps domain containing protein 2
chr16_-_83132785 0.05 ENSRNOT00000043449
Rho guanine nucleotide exchange factor 7
chr15_-_55277713 0.05 ENSRNOT00000023037
integral membrane protein 2B
chr20_-_5212624 0.05 ENSRNOT00000074261
antigen peptide transporter 2
chr5_-_155143539 0.05 ENSRNOT00000016983
Eph receptor B2
chr1_+_164380577 0.05 ENSRNOT00000055321
glycerophosphodiester phosphodiesterase domain containing 5
chr16_+_49266903 0.05 ENSRNOT00000014704
solute carrier family 25 member 4
chr3_+_3389612 0.05 ENSRNOT00000041984
ribosomal protein L8
chr12_-_22021851 0.05 ENSRNOT00000039280
TSC22 domain family, member 4
chr5_+_138300107 0.05 ENSRNOT00000047151
claudin 19
chr1_-_222177421 0.05 ENSRNOT00000078393
estrogen related receptor, alpha
chr20_+_40769586 0.05 ENSRNOT00000001079
fatty acid binding protein 7
chr5_+_152466331 0.05 ENSRNOT00000082841
uncharacterized LOC108351043
chr7_+_76980040 0.05 ENSRNOT00000050726
40S ribosomal protein S29
chr16_-_82100222 0.05 ENSRNOT00000023163
ATPase phospholipid transporting 11A
chr16_+_21178138 0.05 ENSRNOT00000027943
GATA zinc finger domain containing 2A
chr20_+_7136007 0.05 ENSRNOT00000000580
high mobility group AT-hook 1
chr18_-_62965538 0.05 ENSRNOT00000025164
metallophosphoesterase 1
chr1_-_101514974 0.05 ENSRNOT00000044788
protein phosphatase 1, regulatory subunit 15A
chr1_-_252550394 0.05 ENSRNOT00000083468
actin, alpha 2, smooth muscle, aorta
chr10_-_13051154 0.05 ENSRNOT00000033457

chr3_+_14889510 0.05 ENSRNOT00000080760
DAB2 interacting protein
chr4_+_88328061 0.05 ENSRNOT00000084775
vomeronasal 1 receptor 87
chr6_+_111076351 0.05 ENSRNOT00000089644
transmembrane protein 63c
chr20_+_1749716 0.05 ENSRNOT00000048856
olfactory receptor 1735
chr20_-_2020537 0.05 ENSRNOT00000011704
zinc finger protein 57
chr5_-_61077627 0.05 ENSRNOT00000015338
SH2 domain containing adaptor protein B
chr7_+_12487361 0.05 ENSRNOT00000077146
strawberry notch homolog 2
chr2_+_221823687 0.04 ENSRNOT00000072735
dihydropyrimidine dehydrogenase
chr2_+_61991742 0.04 ENSRNOT00000046715
LRRGT00154
chr1_-_174350196 0.04 ENSRNOT00000055158
similar to predicted gene ICRFP703B1614Q5.5
chr9_+_46962288 0.04 ENSRNOT00000082146
interleukin 1 receptor type 1
chr10_+_90988732 0.04 ENSRNOT00000003892
family with sequence similarity 187, member A
chr1_-_170318935 0.04 ENSRNOT00000024119
protein kinase C, delta binding protein
chr14_+_18983853 0.04 ENSRNOT00000003836
Ras association domain family member 6
chr4_+_55715744 0.04 ENSRNOT00000010429
ADP-ribosylation factor 5
chr17_+_32904119 0.04 ENSRNOT00000059854
serpin family B member 1A
chr1_-_8751198 0.04 ENSRNOT00000030511
adhesion G protein-coupled receptor G6
chr5_-_33182147 0.04 ENSRNOT00000080358
MAGE family member D2
chr1_-_222197252 0.04 ENSRNOT00000028707
G protein-coupled receptor 137
chr8_-_55177818 0.04 ENSRNOT00000013960
heat shock protein family B (small) member 2
chr5_+_153269526 0.04 ENSRNOT00000091494
SYF2 pre-mRNA-splicing factor
chr7_+_139698148 0.04 ENSRNOT00000078579
phosphofructokinase, muscle
chr7_-_143420027 0.04 ENSRNOT00000082863
keratin 2
chr6_-_62798384 0.04 ENSRNOT00000093200
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 10-like 1
chr8_+_32188617 0.04 ENSRNOT00000081145
zinc finger and BTB domain containing 44

Network of associatons between targets according to the STRING database.

First level regulatory network of Nfic_Nfib

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 GO:0060155 platelet dense granule organization(GO:0060155)
0.2 0.5 GO:1902303 negative regulation of potassium ion export(GO:1902303)
0.1 0.5 GO:1901423 response to benzene(GO:1901423)
0.1 0.6 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.1 0.6 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.1 0.3 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1 0.4 GO:0046087 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.1 0.3 GO:0010986 positive regulation of lipoprotein particle clearance(GO:0010986)
0.1 0.3 GO:1904209 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209) positive regulation of metalloendopeptidase activity(GO:1904685)
0.1 0.1 GO:1905072 cardiac jelly development(GO:1905072)
0.1 0.2 GO:2000820 negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)
0.1 0.2 GO:0034769 basement membrane disassembly(GO:0034769)
0.1 0.4 GO:0018879 biphenyl metabolic process(GO:0018879)
0.1 0.2 GO:1903903 protein processing in phagocytic vesicle(GO:1900756) regulation of establishment of T cell polarity(GO:1903903) regulation of protein processing in phagocytic vesicle(GO:1903921) positive regulation of protein processing in phagocytic vesicle(GO:1903923)
0.1 0.2 GO:1900147 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.1 0.2 GO:0007468 regulation of rhodopsin gene expression(GO:0007468)
0.0 0.2 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.0 0.5 GO:0019372 lipoxygenase pathway(GO:0019372)
0.0 0.1 GO:0090648 regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734) response to methyl methanesulfonate(GO:0072702) cellular response to methyl methanesulfonate(GO:0072703) response to environmental enrichment(GO:0090648) positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.0 0.1 GO:0071298 cellular response to L-ascorbic acid(GO:0071298)
0.0 0.2 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.0 0.1 GO:0010752 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) negative regulation of nitric oxide mediated signal transduction(GO:0010751) regulation of cGMP-mediated signaling(GO:0010752) negative regulation of endothelial cell chemotaxis(GO:2001027)
0.0 0.1 GO:1902462 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.0 0.2 GO:0071224 cellular response to peptidoglycan(GO:0071224)
0.0 0.1 GO:0060279 positive regulation of ovulation(GO:0060279)
0.0 0.1 GO:0097069 cellular response to thyroxine stimulus(GO:0097069)
0.0 0.1 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.0 0.1 GO:0046086 adenosine biosynthetic process(GO:0046086)
0.0 0.2 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.2 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.0 0.1 GO:1904178 sterol regulatory element binding protein import into nucleus(GO:0035105) negative regulation of adipose tissue development(GO:1904178)
0.0 0.1 GO:1904253 positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253)
0.0 0.1 GO:0034165 positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
0.0 0.1 GO:0006114 glycerol biosynthetic process(GO:0006114)
0.0 0.1 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
0.0 0.1 GO:0030200 proteoglycan catabolic process(GO:0030167) heparan sulfate proteoglycan catabolic process(GO:0030200)
0.0 0.1 GO:0097052 L-kynurenine metabolic process(GO:0097052)
0.0 0.3 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.1 GO:0060623 pericentric heterochromatin assembly(GO:0031508) regulation of chromosome condensation(GO:0060623)
0.0 0.1 GO:0051935 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.0 0.3 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.4 GO:0032060 bleb assembly(GO:0032060)
0.0 0.2 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 0.1 GO:0055073 cadmium ion homeostasis(GO:0055073)
0.0 0.1 GO:0003350 pulmonary myocardium development(GO:0003350) subthalamus development(GO:0021539) deltoid tuberosity development(GO:0035993) left lung morphogenesis(GO:0060460) pulmonary vein morphogenesis(GO:0060577)
0.0 0.1 GO:0055118 negative regulation of cardiac muscle contraction(GO:0055118)
0.0 0.1 GO:0075509 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.0 0.1 GO:0044691 tooth eruption(GO:0044691)
0.0 0.1 GO:0035995 detection of muscle stretch(GO:0035995)
0.0 0.1 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.0 0.1 GO:0061156 embryonic heart tube left/right pattern formation(GO:0060971) pulmonary artery morphogenesis(GO:0061156)
0.0 0.1 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.0 0.2 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.0 GO:0035986 senescence-associated heterochromatin focus assembly(GO:0035986)
0.0 0.1 GO:1904714 positive regulation of Schwann cell proliferation(GO:0010625) regulation of chaperone-mediated autophagy(GO:1904714)
0.0 0.0 GO:0071348 cellular response to interleukin-11(GO:0071348)
0.0 0.0 GO:0046127 thymidine catabolic process(GO:0006214) pyrimidine deoxyribonucleoside catabolic process(GO:0046127)
0.0 0.1 GO:0050748 negative regulation of lipoprotein metabolic process(GO:0050748) regulation of protein lipidation(GO:1903059)
0.0 0.1 GO:0070314 G1 to G0 transition(GO:0070314)
0.0 0.1 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 0.1 GO:0099545 trans-synaptic signaling by trans-synaptic complex(GO:0099545)
0.0 0.1 GO:2000277 positive regulation of oxidative phosphorylation uncoupler activity(GO:2000277)
0.0 0.1 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.1 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0 0.0 GO:0072144 glomerular mesangial cell development(GO:0072144)
0.0 0.0 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
0.0 0.3 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.0 0.1 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.0 0.1 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.0 0.1 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.1 GO:0009624 response to nematode(GO:0009624)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 GO:0031083 BLOC-1 complex(GO:0031083)
0.1 0.3 GO:0030478 actin cap(GO:0030478)
0.0 0.3 GO:0033269 internode region of axon(GO:0033269)
0.0 0.2 GO:0045098 type III intermediate filament(GO:0045098)
0.0 0.1 GO:0071953 elastic fiber(GO:0071953)
0.0 0.1 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
0.0 0.1 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 0.1 GO:0001740 Barr body(GO:0001740)
0.0 0.0 GO:1990032 parallel fiber(GO:1990032)
0.0 0.1 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.3 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.2 GO:0042581 specific granule(GO:0042581)
0.0 0.0 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.0 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.3 GO:0042629 mast cell granule(GO:0042629)
0.0 0.1 GO:0000322 storage vacuole(GO:0000322)
0.0 0.0 GO:0097233 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0016748 succinyltransferase activity(GO:0016748)
0.1 1.5 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.1 0.4 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 0.3 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733)
0.1 0.2 GO:0035939 microsatellite binding(GO:0035939)
0.1 0.5 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.1 0.2 GO:0004736 pyruvate carboxylase activity(GO:0004736)
0.1 0.6 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.2 GO:1990254 keratin filament binding(GO:1990254)
0.0 0.2 GO:0045159 myosin II binding(GO:0045159)
0.0 0.1 GO:0005163 nerve growth factor receptor binding(GO:0005163)
0.0 0.1 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.0 0.1 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
0.0 0.3 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.2 GO:0010853 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.0 0.1 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.0 0.1 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.0 0.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.2 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.2 GO:1901612 phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612)
0.0 0.1 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.1 GO:0070052 collagen V binding(GO:0070052)
0.0 0.1 GO:0004103 choline kinase activity(GO:0004103)
0.0 0.4 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.1 GO:0004956 prostaglandin D receptor activity(GO:0004956)
0.0 0.2 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.1 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.0 0.2 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.1 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.1 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 0.0 GO:0004159 dihydrouracil dehydrogenase (NAD+) activity(GO:0004159) dihydropyrimidine dehydrogenase (NADP+) activity(GO:0017113)
0.0 0.5 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 0.0 GO:0005333 norepinephrine transmembrane transporter activity(GO:0005333)
0.0 0.1 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.2 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.3 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.3 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.0 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.0 0.0 GO:0052723 inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.0 0.2 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.0 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.1 GO:0015440 peptide-transporting ATPase activity(GO:0015440)
0.0 0.1 GO:1990932 5.8S rRNA binding(GO:1990932)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.2 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.5 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.5 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 1.2 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.4 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.4 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.3 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.3 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.1 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.0 0.2 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly