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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Hic1

Z-value: 1.82

Motif logo

Transcription factors associated with Hic1

Gene Symbol Gene ID Gene Info
ENSRNOG00000046405 HIC ZBTB transcriptional repressor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hic1rn6_v1_chr10_-_62009582_620095820.612.7e-01Click!

Activity profile of Hic1 motif

Sorted Z-values of Hic1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr14_+_104191517 1.75 ENSRNOT00000006573
sprouty-related, EVH1 domain containing 2
chr1_+_226435979 1.59 ENSRNOT00000048704
ENSRNOT00000036232
ENSRNOT00000035576
ENSRNOT00000036180
ENSRNOT00000036168
ENSRNOT00000047964
ENSRNOT00000036283
ENSRNOT00000007429
synaptotagmin 7
chr20_+_4993560 1.46 ENSRNOT00000081628
ENSRNOT00000087861
ENSRNOT00000001160
valyl-tRNA synthetase
chr8_-_6203515 1.25 ENSRNOT00000087278
ENSRNOT00000031189
ENSRNOT00000008074
ENSRNOT00000085285
ENSRNOT00000007866
yes-associated protein 1
chr3_-_2803574 1.23 ENSRNOT00000040995
similar to Gene model 996
chr7_+_130498199 1.10 ENSRNOT00000092684
ENSRNOT00000092431
SH3 and multiple ankyrin repeat domains 3
chr4_-_68597586 1.09 ENSRNOT00000015921
similar to RIKEN cDNA E330009J07 gene
chr6_+_137824213 1.07 ENSRNOT00000056880
phosphofurin acidic cluster sorting protein 2
chr1_+_266953139 1.04 ENSRNOT00000054696
neuralized E3 ubiquitin protein ligase 1
chr4_-_145147397 1.03 ENSRNOT00000010347
lipoma HMGIC fusion partner-like 4
chr7_+_125649688 0.99 ENSRNOT00000017906
PHD finger protein 21B
chr9_+_17841410 0.99 ENSRNOT00000031706
transmembrane protein 151B
chr9_+_70133969 0.97 ENSRNOT00000040525
ADAM metallopeptidase domain 23
chr3_+_161433410 0.96 ENSRNOT00000024657
solute carrier family 12 member 5
chr7_-_126465723 0.95 ENSRNOT00000021196
wingless-type MMTV integration site family, member 7B
chr8_+_130749838 0.95 ENSRNOT00000079273
SNF related kinase
chr3_-_1924827 0.93 ENSRNOT00000006162
calcium voltage-gated channel subunit alpha1 B
chr3_+_124896618 0.93 ENSRNOT00000028888
CDP-diacylglycerol synthase 2
chr20_+_13044104 0.93 ENSRNOT00000066017
disco-interacting protein 2 homolog A
chr12_-_38869346 0.92 ENSRNOT00000001807
SET domain containing 1B
chr3_-_38277440 0.91 ENSRNOT00000037857
signal transducing adaptor molecule 2
chr6_-_65319527 0.88 ENSRNOT00000005618
syntaxin binding protein 6
chr14_-_78902063 0.84 ENSRNOT00000088469
protein phosphatase 2, regulatory subunit B, gamma
chr6_-_99783047 0.82 ENSRNOT00000009028
spectrin, beta, erythrocytic
chr11_-_65759581 0.81 ENSRNOT00000034334
leucine rich repeat containing 58
chr1_+_173607101 0.76 ENSRNOT00000074636
tubby bipartite transcription factor
chr14_+_81819799 0.75 ENSRNOT00000076840
Max dimerization protein 4
chr5_-_172623899 0.74 ENSRNOT00000080591
SKI proto-oncogene
chr5_-_166133491 0.74 ENSRNOT00000087739
ENSRNOT00000089099
kinesin family member 1B
chr11_-_71108184 0.73 ENSRNOT00000051989
ENSRNOT00000073865
ENSRNOT00000063883
leucine rich repeats and calponin homology domain containing 3
chr1_+_162083030 0.73 ENSRNOT00000016361
GRB2-associated binding protein 2
chr11_+_30550141 0.73 ENSRNOT00000002866
hormonally upregulated Neu-associated kinase
chr1_+_15412603 0.71 ENSRNOT00000051496
ENSRNOT00000067070
mitogen-activated protein kinase kinase kinase 5
chr3_-_164239250 0.69 ENSRNOT00000012604
spermatogenesis associated 2
chr8_-_115981910 0.69 ENSRNOT00000019867
dedicator of cyto-kinesis 3
chr7_+_11033317 0.68 ENSRNOT00000007498
guanine nucleotide binding protein, alpha 11
chr6_+_132219088 0.67 ENSRNOT00000034883
HHIP-like 1
chr19_-_53688597 0.67 ENSRNOT00000074448
zinc finger CCHC-type containing 14
chr8_+_116154736 0.67 ENSRNOT00000021218
calcium voltage-gated channel auxiliary subunit alpha2delta 2
chr10_-_63952726 0.66 ENSRNOT00000090461
double C2 domain beta
chr2_+_151685251 0.66 ENSRNOT00000019340
RAP2B, member of RAS oncogene family
chr1_+_113034227 0.64 ENSRNOT00000081831
ENSRNOT00000077877
ENSRNOT00000077594
gamma-aminobutyric acid type A receptor beta 3 subunit
chr20_+_46428124 0.64 ENSRNOT00000000327
forkhead box O3
chr10_+_70627401 0.63 ENSRNOT00000076897
RAS-like, family 10, member B
chr7_-_12393266 0.63 ENSRNOT00000021709
ephrin A2
chr17_-_10208360 0.63 ENSRNOT00000087397
unc-5 netrin receptor A
chr14_+_87312203 0.62 ENSRNOT00000088032
adenylate cyclase 1
chr14_-_82287706 0.61 ENSRNOT00000080695
fibroblast growth factor receptor 3
chr2_+_34186091 0.61 ENSRNOT00000016129
small glutamine rich tetratricopeptide repeat containing beta
chr7_-_113937941 0.60 ENSRNOT00000012408
potassium two pore domain channel subfamily K member 9
chr11_+_57207656 0.60 ENSRNOT00000038207
ENSRNOT00000085754
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr1_-_125967756 0.59 ENSRNOT00000031488
family with sequence similarity 189, member A1
chr20_+_13940877 0.59 ENSRNOT00000093587
calcineurin binding protein 1
chr10_+_67862054 0.59 ENSRNOT00000031746
cyclin-dependent kinase 5 regulatory subunit 1
chr9_+_94980409 0.58 ENSRNOT00000035338
diacylglycerol kinase, delta
chr4_+_120671489 0.57 ENSRNOT00000029125
monoglyceride lipase
chr7_+_2875909 0.56 ENSRNOT00000028244
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
chr1_+_278557792 0.55 ENSRNOT00000023414
attractin like 1
chr10_-_74298599 0.55 ENSRNOT00000007379
yippee-like 2
chr10_+_11392625 0.55 ENSRNOT00000072802
adenylate cyclase 9
chr14_+_60857989 0.55 ENSRNOT00000034411
coiled-coil domain containing 149
chr7_+_70364813 0.54 ENSRNOT00000084012
ENSRNOT00000031230
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr6_-_135939534 0.54 ENSRNOT00000052237
DIRAS family GTPase 3
chr2_-_24923128 0.53 ENSRNOT00000044087
phosphodiesterase 8B
chr12_+_28381982 0.53 ENSRNOT00000076101
Williams-Beuren syndrome chromosome region 17
chr10_-_17075139 0.52 ENSRNOT00000039398
neuralized E3 ubiquitin protein ligase 1B
chr20_-_31597830 0.52 ENSRNOT00000085877
collagen type XIII alpha 1 chain
chr6_+_144156175 0.52 ENSRNOT00000006582
extended synaptotagmin 2
chr10_+_6975244 0.51 ENSRNOT00000046232
ubiquitin specific peptidase 7
chr3_-_11885311 0.51 ENSRNOT00000021189
ENSRNOT00000021178
syntaxin binding protein 1
chr10_-_56530842 0.51 ENSRNOT00000077451

chr5_+_169259283 0.51 ENSRNOT00000084487
pleckstrin homology and RhoGEF domain containing G5
chr12_-_44520341 0.51 ENSRNOT00000066810
nitric oxide synthase 1
chr18_+_52423883 0.50 ENSRNOT00000022017
proline-rich coiled-coil 1
chr1_-_166912524 0.50 ENSRNOT00000092952
inositol polyphosphate phosphatase-like 1
chr3_+_6211789 0.50 ENSRNOT00000012892
retinoid X receptor alpha
chr5_+_139783951 0.49 ENSRNOT00000081333
regulating synaptic membrane exocytosis 3
chr20_-_8574082 0.49 ENSRNOT00000048845
MAM domain containing glycosylphosphatidylinositol anchor 1
chr7_+_11737293 0.49 ENSRNOT00000046059
leucine rich repeat and Ig domain containing 3
chr19_-_19832812 0.49 ENSRNOT00000084657
poly(A) RNA polymerase D5, non-canonical
chr15_-_43542939 0.49 ENSRNOT00000012996
dihydropyrimidinase-like 2
chr11_-_44292884 0.49 ENSRNOT00000084060
discoidin, CUB and LCCL domain containing 2
chr19_-_31942180 0.48 ENSRNOT00000024924
OTU deubiquitinase 4
chr19_+_54060622 0.48 ENSRNOT00000023607
Gse1 coiled-coil protein
chr13_+_110920830 0.47 ENSRNOT00000077014
ENSRNOT00000076362
potassium voltage-gated channel subfamily H member 1
chr3_+_8928534 0.47 ENSRNOT00000088509
ENSRNOT00000065300
mitoguardin 2
chr4_+_88695590 0.47 ENSRNOT00000087835
protein phosphatase, Mg2+/Mn2+ dependent, 1K
chr10_-_105552986 0.47 ENSRNOT00000014699
ubiquitin-conjugating enzyme E2O
chr16_-_6404957 0.47 ENSRNOT00000048459
calcium voltage-gated channel subunit alpha1 D
chr1_-_164977633 0.46 ENSRNOT00000029629
ring finger protein 169
chr8_+_117486083 0.45 ENSRNOT00000027552
ENSRNOT00000088705
protein kinase cAMP-dependent type 2 regulatory subunit alpha
chr1_-_52992213 0.44 ENSRNOT00000033528
proline rich 18
chr12_-_9331195 0.44 ENSRNOT00000044134
PAN3 poly(A) specific ribonuclease subunit
chr18_-_37819097 0.43 ENSRNOT00000025880
dihydropyrimidinase-like 3
chr7_+_97559841 0.43 ENSRNOT00000007326
zinc fingers and homeoboxes 2
chr18_-_63357194 0.43 ENSRNOT00000089408
ENSRNOT00000066103
spire-type actin nucleation factor 1
chr18_-_57114545 0.43 ENSRNOT00000026495
actin filament associated protein 1-like 1
chr4_+_9347528 0.42 ENSRNOT00000010521
reelin
chr17_+_16106137 0.42 ENSRNOT00000060568
family with sequence similarity 120A
chr6_-_27643076 0.42 ENSRNOT00000074348
GRB2 associated regulator of MAPK1 subtype 2
chr1_-_281874456 0.42 ENSRNOT00000084760
ENSRNOT00000050617
CDK2-associated, cullin domain 1
chr4_-_115157263 0.42 ENSRNOT00000015296
tet methylcytosine dioxygenase 3
chr3_+_116899878 0.42 ENSRNOT00000090802
ENSRNOT00000066101
semaphorin 6D
chr3_+_134413170 0.41 ENSRNOT00000074338

chr2_-_178334900 0.41 ENSRNOT00000090152
folliculin interacting protein 2
chr10_+_61432819 0.41 ENSRNOT00000003687
ENSRNOT00000092478
clustered mitochondria homolog
chr3_-_110492398 0.41 ENSRNOT00000056450
ankyrin repeat domain 63
chr12_+_660011 0.41 ENSRNOT00000040830
PDS5 cohesin associated factor B
chr17_-_84488480 0.41 ENSRNOT00000000158
ENSRNOT00000075983
nebulette
chr1_-_212622537 0.41 ENSRNOT00000025609
shadow of prion protein homolog (zebrafish)
chr1_+_100593892 0.41 ENSRNOT00000027062
potassium voltage-gated channel subfamily C member 3
chr10_-_14373334 0.40 ENSRNOT00000022050
cramped chromatin regulator homolog 1
chr1_-_164590562 0.40 ENSRNOT00000024157
trophoblast glycoprotein-like
chr16_-_60208462 0.40 ENSRNOT00000015203
malignant fibrous histiocytoma amplified sequence 1
chr10_+_62674561 0.40 ENSRNOT00000019946
ENSRNOT00000056110
ankyrin repeat domain 13B
chr8_-_94563760 0.40 ENSRNOT00000032792
synaptosomal-associated protein 91
chr5_+_79382096 0.39 ENSRNOT00000085461
transmembrane protein 268
chr6_-_122897997 0.39 ENSRNOT00000057601
echinoderm microtubule associated protein like 5
chr8_+_119566509 0.39 ENSRNOT00000028633
tetratricopeptide repeat and ankyrin repeat containing 1
chr1_+_263186235 0.39 ENSRNOT00000021876
cyclin and CBS domain divalent metal cation transport mediator 1
chr9_+_94425252 0.39 ENSRNOT00000064965
ENSRNOT00000076099
GRB10 interacting GYF protein 2
chr17_+_13670520 0.39 ENSRNOT00000019442
SHC adaptor protein 3
chr5_+_138470069 0.39 ENSRNOT00000076343
ENSRNOT00000064073
zinc finger, MYND-type containing 12
chr1_-_127599257 0.39 ENSRNOT00000018436
ankyrin repeat and SOCS box-containing 7
chr1_-_188101566 0.39 ENSRNOT00000092435
synaptotagmin 17
chr20_+_46429222 0.38 ENSRNOT00000076818
forkhead box O3
chr18_-_57245666 0.38 ENSRNOT00000080365
actin binding LIM protein family, member 3
chr12_-_47793534 0.38 ENSRNOT00000001588
family with sequence similarity 222, member A
chr2_+_62236577 0.38 ENSRNOT00000036633
myotubularin related protein 12
chr11_-_72378895 0.38 ENSRNOT00000058885
discs large MAGUK scaffold protein 1
chr10_-_82399484 0.38 ENSRNOT00000082972
ENSRNOT00000055582
xylosyltransferase 2
chr10_+_66942398 0.38 ENSRNOT00000018986
RAB11 family interacting protein 4
chr3_+_108795235 0.38 ENSRNOT00000007028
sprouty-related, EVH1 domain containing 1
chr4_+_120672152 0.38 ENSRNOT00000077231
monoglyceride lipase
chr4_+_122282279 0.38 ENSRNOT00000038244
ZXD family zinc finger C
chr1_-_210739600 0.38 ENSRNOT00000031734
transcription elongation regulator 1-like
chr15_-_41770112 0.37 ENSRNOT00000034400
karyopherin subunit alpha 3
chr6_-_125853461 0.37 ENSRNOT00000007505
ataxin 3
chr1_+_86873253 0.37 ENSRNOT00000071239
F-box protein 27
chr8_+_111600532 0.37 ENSRNOT00000081952
RAB6B, member RAS oncogene family
chr13_-_51076852 0.37 ENSRNOT00000078993
adenosine A1 receptor
chr12_-_39396042 0.37 ENSRNOT00000001746
purinergic receptor P2X 7
chr12_-_40417654 0.36 ENSRNOT00000072481
BRCA1 associated protein
chr12_-_25638797 0.36 ENSRNOT00000002033
GATS protein-like 2
chr1_+_222519615 0.36 ENSRNOT00000083585
REST corepressor 2
chr10_+_61685645 0.36 ENSRNOT00000003933
MAX network transcriptional repressor
chr4_+_9347779 0.35 ENSRNOT00000061858
reelin
chr1_+_100593680 0.35 ENSRNOT00000078153
ENSRNOT00000027063
potassium voltage-gated channel subfamily C member 3
chr11_+_84321078 0.35 ENSRNOT00000058043
MAP6 domain containing 1
chr10_-_88754829 0.35 ENSRNOT00000026354
signal transducer and activator of transcription 5B
chr6_-_111015598 0.35 ENSRNOT00000015046
zinc finger, DHHC-type containing 22
chr1_+_282134981 0.35 ENSRNOT00000036203
nanos C2HC-type zinc finger 1
chr15_+_19547871 0.35 ENSRNOT00000036235
G protein-coupled receptor 137C
chr12_-_38638536 0.35 ENSRNOT00000001690
MLX interacting protein
chr7_+_80713321 0.35 ENSRNOT00000091355
ENSRNOT00000078354
oxidation resistance 1
chr7_+_11152038 0.35 ENSRNOT00000006168
nuclear factor I/C
chr10_-_68517564 0.34 ENSRNOT00000086961
acid sensing ion channel subunit 2
chr19_+_46761570 0.34 ENSRNOT00000058779
WW domain-containing oxidoreductase
chr9_-_110936631 0.34 ENSRNOT00000064431
F-box and leucine-rich repeat protein 17
chr10_-_46172166 0.34 ENSRNOT00000091052
ENSRNOT00000004412
folliculin
chr3_+_147609095 0.34 ENSRNOT00000041456
sulfiredoxin 1
chr3_+_8802852 0.34 ENSRNOT00000033934
leucine rich repeat containing 8 family, member A
chr5_+_59348639 0.34 ENSRNOT00000084031
ENSRNOT00000060264
reversion-inducing-cysteine-rich protein with kazal motifs
chr7_-_123445613 0.34 ENSRNOT00000070937
shisa family member 8
chr13_+_51384562 0.34 ENSRNOT00000077928
lysine demethylase 5B
chr14_-_104375649 0.34 ENSRNOT00000006607
ARP2 actin related protein 2 homolog
chr13_-_53224768 0.33 ENSRNOT00000091015
calmodulin regulated spectrin-associated protein family, member 2
chr16_+_17538855 0.33 ENSRNOT00000014772
tetraspanin 14
chr1_+_85437780 0.33 ENSRNOT00000093740
SPT5 homolog, DSIF elongation factor subunit
chr1_+_251421596 0.32 ENSRNOT00000028143
phosphatase and tensin homolog
chr1_-_175420106 0.32 ENSRNOT00000013126
ENSRNOT00000077125
SET binding factor 2
chr2_-_232178533 0.32 ENSRNOT00000082173
ENSRNOT00000055607
adaptor-related protein complex 1 associated regulatory protein
chr7_-_123767797 0.32 ENSRNOT00000012699
transcription factor 20
chr3_+_142739781 0.31 ENSRNOT00000006181
somatostatin receptor 4
chr12_+_36871999 0.31 ENSRNOT00000001334
ENSRNOT00000084236
nuclear receptor co-repressor 2
chr5_-_154363329 0.31 ENSRNOT00000064596
elongin A
chr8_-_76940094 0.31 ENSRNOT00000082709
ENSRNOT00000084313
ring finger protein 111
chr6_-_105097054 0.31 ENSRNOT00000048606
solute carrier family 8 member A3
chr19_+_21218465 0.31 ENSRNOT00000049285
Nedd4 binding protein 1
chr9_+_82120059 0.31 ENSRNOT00000057368
cyclin-dependent kinase 5 regulatory subunit 2
chr5_+_160355833 0.30 ENSRNOT00000080721
ENSRNOT00000088523
ENSRNOT00000017972
caspase 9
chr9_-_38495126 0.30 ENSRNOT00000016933
ENSRNOT00000090385
RAB23, member RAS oncogene family
chr19_+_784618 0.30 ENSRNOT00000014749
CKLF-like MARVEL transmembrane domain containing 4
chr20_+_8285502 0.30 ENSRNOT00000081715
ring finger protein 8
chr17_-_18592750 0.30 ENSRNOT00000065742
CAP, adenylate cyclase-associated protein, 2 (yeast)
chr2_+_226900619 0.30 ENSRNOT00000019638
phosphodiesterase 5A
chr3_-_123376455 0.30 ENSRNOT00000028842
RGD1565616
chr16_+_20740826 0.30 ENSRNOT00000038057
CREB regulated transcription coactivator 1
chr19_-_40925660 0.30 ENSRNOT00000023645
MTSS1L, I-BAR domain containing
chr9_-_100592271 0.30 ENSRNOT00000086433
high density lipoprotein binding protein
chr10_-_56491715 0.30 ENSRNOT00000020970
potassium channel tetramerization domain containing 11
chr5_+_79055521 0.29 ENSRNOT00000010333
collagen type XXVII alpha 1 chain
chr9_+_53627208 0.29 ENSRNOT00000083487
major facilitator superfamily domain containing 6
chr8_+_62368998 0.29 ENSRNOT00000025885
unc-51 like kinase 3
chr3_+_177164359 0.29 ENSRNOT00000066837
RGD1561282
chr16_+_71090045 0.29 ENSRNOT00000020832
DDHD domain containing 2
chr7_+_11930135 0.29 ENSRNOT00000025391
BTB domain containing 2
chr17_-_27112820 0.29 ENSRNOT00000018359
bone morphogenetic protein 6
chr3_-_125213607 0.29 ENSRNOT00000078070
glycerophosphocholine phosphodiesterase 1
chr18_-_6082997 0.29 ENSRNOT00000086335
ENSRNOT00000032454
SS18, nBAF chromatin remodeling complex subunit

Network of associatons between targets according to the STRING database.

First level regulatory network of Hic1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:1990926 short-term synaptic potentiation(GO:1990926)
0.5 1.5 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.3 1.0 GO:0072054 renal outer medulla development(GO:0072054)
0.2 1.0 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.2 0.7 GO:0035544 negative regulation of SNARE complex assembly(GO:0035544)
0.2 1.9 GO:2000969 positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.2 0.9 GO:0021586 pons maturation(GO:0021586)
0.2 0.6 GO:0003050 regulation of systemic arterial blood pressure by atrial natriuretic peptide(GO:0003050)
0.2 0.6 GO:0021898 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898)
0.2 0.4 GO:1904170 regulation of bleb assembly(GO:1904170)
0.2 0.7 GO:0071879 positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.2 0.5 GO:1903760 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760)
0.2 0.6 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.2 1.2 GO:0072257 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.2 0.5 GO:0032242 regulation of nucleoside transport(GO:0032242)
0.2 1.1 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.2 0.3 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
0.1 0.7 GO:0010626 negative regulation of Schwann cell proliferation(GO:0010626)
0.1 1.0 GO:1990785 response to water-immersion restraint stress(GO:1990785)
0.1 0.9 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.1 0.7 GO:0019520 aldonic acid metabolic process(GO:0019520) D-gluconate metabolic process(GO:0019521)
0.1 0.4 GO:0070649 formin-nucleated actin cable assembly(GO:0070649)
0.1 0.4 GO:0044725 chromatin reprogramming in the zygote(GO:0044725)
0.1 0.4 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
0.1 0.4 GO:2000040 regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.1 0.5 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.1 0.4 GO:0003249 cell proliferation involved in heart valve morphogenesis(GO:0003249) regulation of cell proliferation involved in heart valve morphogenesis(GO:0003250)
0.1 0.4 GO:0046671 negative regulation of retinal cell programmed cell death(GO:0046671)
0.1 0.1 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909)
0.1 0.8 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.1 0.4 GO:1901856 negative regulation of cellular respiration(GO:1901856)
0.1 0.3 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.1 0.3 GO:0098749 cerebellar neuron development(GO:0098749)
0.1 0.3 GO:1903849 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.1 0.6 GO:0061144 alveolar secondary septum development(GO:0061144)
0.1 0.3 GO:1904348 eye blink reflex(GO:0060082) negative regulation of gastro-intestinal system smooth muscle contraction(GO:1904305) regulation of small intestine smooth muscle contraction(GO:1904347) negative regulation of small intestine smooth muscle contraction(GO:1904348) small intestine smooth muscle contraction(GO:1990770)
0.1 2.1 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.1 0.6 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.1 1.0 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.1 0.5 GO:0035106 operant conditioning(GO:0035106)
0.1 0.6 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.1 0.9 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.1 0.2 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.1 0.3 GO:0055118 negative regulation of cardiac muscle contraction(GO:0055118)
0.1 0.9 GO:0045634 regulation of melanocyte differentiation(GO:0045634)
0.1 0.5 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.1 0.3 GO:2000182 regulation of progesterone biosynthetic process(GO:2000182)
0.1 0.4 GO:0030210 heparin biosynthetic process(GO:0030210)
0.1 0.8 GO:0003025 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025)
0.1 0.4 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.1 0.4 GO:0046544 development of secondary male sexual characteristics(GO:0046544)
0.1 0.4 GO:1904684 negative regulation of metalloendopeptidase activity(GO:1904684)
0.1 0.3 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.1 0.3 GO:0072218 ascending thin limb development(GO:0072021) metanephric ascending thin limb development(GO:0072218)
0.1 0.5 GO:0097338 response to clozapine(GO:0097338)
0.1 0.3 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.2 GO:0048619 embryonic hindgut morphogenesis(GO:0048619)
0.1 0.3 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.1 0.9 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.1 0.2 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.1 0.1 GO:0070602 regulation of centromeric sister chromatid cohesion(GO:0070602)
0.1 0.2 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.1 1.1 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.1 0.5 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.1 0.3 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.1 0.3 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.1 0.3 GO:0038169 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.1 0.2 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.1 0.3 GO:1900625 regulation of mast cell cytokine production(GO:0032763) regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.1 0.5 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.1 0.3 GO:0031394 positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.1 0.7 GO:0033523 histone H2B ubiquitination(GO:0033523)
0.1 0.4 GO:0021960 anterior commissure morphogenesis(GO:0021960)
0.1 0.2 GO:0036394 amylase secretion(GO:0036394)
0.1 0.3 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.1 0.1 GO:0060734 regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734)
0.1 0.2 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.1 0.2 GO:0051695 actin filament uncapping(GO:0051695)
0.1 0.3 GO:2000973 regulation of pro-B cell differentiation(GO:2000973)
0.1 0.2 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.1 0.2 GO:0000912 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.1 0.4 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.1 0.2 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.1 0.5 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
0.1 0.3 GO:1902525 regulation of protein monoubiquitination(GO:1902525)
0.1 0.2 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.1 0.8 GO:0033008 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.1 0.2 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.1 GO:0034241 positive regulation of macrophage fusion(GO:0034241) PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0 0.6 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.7 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.2 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.1 GO:2000587 negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.0 0.3 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.2 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.0 0.2 GO:1904009 cellular response to monosodium glutamate(GO:1904009)
0.0 0.3 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0 0.1 GO:0021747 cochlear nucleus development(GO:0021747)
0.0 0.1 GO:0060689 cell differentiation involved in salivary gland development(GO:0060689)
0.0 0.7 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.0 0.1 GO:1902211 regulation of prolactin signaling pathway(GO:1902211)
0.0 0.5 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.2 GO:0042851 L-alanine metabolic process(GO:0042851)
0.0 0.1 GO:1990167 protein K27-linked deubiquitination(GO:1990167)
0.0 0.1 GO:0070428 regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428)
0.0 0.3 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.0 0.2 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.0 0.4 GO:0006498 N-terminal protein lipidation(GO:0006498)
0.0 0.3 GO:0002326 B cell lineage commitment(GO:0002326)
0.0 0.1 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151)
0.0 0.8 GO:0010666 positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666)
0.0 0.2 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
0.0 0.2 GO:0098881 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.0 0.5 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.0 0.2 GO:1902608 regulation of large conductance calcium-activated potassium channel activity(GO:1902606) positive regulation of large conductance calcium-activated potassium channel activity(GO:1902608)
0.0 0.1 GO:0042723 thiamine metabolic process(GO:0006772) thiamine diphosphate metabolic process(GO:0042357) thiamine-containing compound metabolic process(GO:0042723)
0.0 0.4 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.3 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.1 GO:0034971 histone H3-R17 methylation(GO:0034971)
0.0 0.4 GO:0070314 G1 to G0 transition(GO:0070314)
0.0 1.0 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.6 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.1 GO:0071579 regulation of zinc ion transport(GO:0071579)
0.0 0.2 GO:0034651 cortisol metabolic process(GO:0034650) cortisol biosynthetic process(GO:0034651)
0.0 0.3 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.0 GO:0045819 positive regulation of glycogen catabolic process(GO:0045819)
0.0 0.3 GO:0014819 regulation of skeletal muscle contraction(GO:0014819)
0.0 0.1 GO:0006435 prolyl-tRNA aminoacylation(GO:0006433) threonyl-tRNA aminoacylation(GO:0006435)
0.0 1.6 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.0 0.2 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.0 0.1 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.0 0.1 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781)
0.0 0.1 GO:2000705 regulation of dense core granule biogenesis(GO:2000705)
0.0 0.2 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.5 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.0 0.3 GO:0006968 cellular defense response(GO:0006968)
0.0 0.1 GO:0061643 chemorepulsion of axon(GO:0061643)
0.0 0.1 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.0 0.1 GO:0097401 synaptic vesicle lumen acidification(GO:0097401)
0.0 0.2 GO:0039689 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.0 0.4 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.6 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.1 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.2 GO:1901503 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.1 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.0 0.3 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.1 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.0 0.2 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.5 GO:2000780 negative regulation of double-strand break repair(GO:2000780)
0.0 0.2 GO:1904251 regulation of bile acid metabolic process(GO:1904251)
0.0 0.2 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.0 0.2 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.0 0.4 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.0 GO:0002424 T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840)
0.0 0.3 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.1 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.0 0.3 GO:0072364 regulation of cellular ketone metabolic process by regulation of transcription from RNA polymerase II promoter(GO:0072364)
0.0 0.1 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.0 0.2 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.1 GO:1902659 regulation of glucose mediated signaling pathway(GO:1902659)
0.0 0.1 GO:2000664 positive regulation of interleukin-5 secretion(GO:2000664)
0.0 0.4 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.2 GO:1903874 ferrous iron transport(GO:0015684) ferrous iron transmembrane transport(GO:1903874)
0.0 0.1 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 0.3 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.0 0.3 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.2 GO:1902414 protein localization to cell junction(GO:1902414)
0.0 0.8 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.0 0.4 GO:0032025 response to cobalt ion(GO:0032025)
0.0 0.1 GO:0010265 SCF complex assembly(GO:0010265)
0.0 1.6 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.0 0.0 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.2 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.1 GO:2000819 regulation of nucleotide-excision repair(GO:2000819)
0.0 0.1 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.1 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.0 0.1 GO:0042489 negative regulation of odontogenesis of dentin-containing tooth(GO:0042489)
0.0 0.3 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090)
0.0 0.6 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.1 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.0 0.4 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 0.1 GO:0060214 endocardium formation(GO:0060214)
0.0 0.3 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.0 GO:0089700 protein kinase D signaling(GO:0089700)
0.0 0.1 GO:0006579 amino-acid betaine catabolic process(GO:0006579)
0.0 0.5 GO:0035767 endothelial cell chemotaxis(GO:0035767)
0.0 0.1 GO:0010045 response to nickel cation(GO:0010045)
0.0 0.1 GO:0031937 positive regulation of chromatin silencing(GO:0031937)
0.0 0.3 GO:0034389 lipid particle organization(GO:0034389) positive regulation of mitochondrial fission(GO:0090141)
0.0 0.1 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.1 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 0.5 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.1 GO:0072104 glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104)
0.0 0.1 GO:0002913 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.0 0.0 GO:0031959 mineralocorticoid receptor signaling pathway(GO:0031959)
0.0 0.0 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.0 1.0 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.1 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.4 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.1 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.2 GO:0042407 cristae formation(GO:0042407)
0.0 0.1 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.7 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.3 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.0 0.2 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.1 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.0 0.1 GO:1902460 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.0 0.1 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 0.4 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
0.0 0.5 GO:0006336 DNA replication-independent nucleosome assembly(GO:0006336)
0.0 0.2 GO:0040023 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 0.1 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.0 0.5 GO:0048009 insulin-like growth factor receptor signaling pathway(GO:0048009)
0.0 0.4 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.2 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.0 0.1 GO:0048105 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
0.0 0.2 GO:0071294 cellular response to zinc ion(GO:0071294)
0.0 0.1 GO:0007263 nitric oxide mediated signal transduction(GO:0007263)
0.0 0.3 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.1 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.0 0.2 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.2 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.1 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586) regulation of gamma-delta T cell activation(GO:0046643)
0.0 0.2 GO:0021860 pyramidal neuron development(GO:0021860)
0.0 0.1 GO:0021800 cerebral cortex tangential migration(GO:0021800)
0.0 0.3 GO:0021535 cell migration in hindbrain(GO:0021535)
0.0 0.0 GO:0061744 motor behavior(GO:0061744)
0.0 0.1 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.0 0.1 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.2 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.1 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.0 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.1 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.0 0.2 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 0.2 GO:0036010 protein localization to endosome(GO:0036010)
0.0 0.0 GO:0003241 growth involved in heart morphogenesis(GO:0003241)
0.0 0.1 GO:0032494 response to peptidoglycan(GO:0032494)
0.0 0.1 GO:0090367 negative regulation of mRNA modification(GO:0090367)
0.0 0.0 GO:0071469 cellular response to alkaline pH(GO:0071469)
0.0 0.0 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.0 0.3 GO:0072112 renal filtration cell differentiation(GO:0061318) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0 0.1 GO:0090168 Golgi reassembly(GO:0090168)
0.0 0.2 GO:0035886 vascular smooth muscle cell differentiation(GO:0035886)
0.0 0.1 GO:0032310 prostaglandin secretion(GO:0032310)
0.0 0.1 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.2 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.1 GO:0042711 maternal behavior(GO:0042711)
0.0 0.1 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.0 GO:0051697 protein delipidation(GO:0051697)
0.0 0.1 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.1 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.0 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0 0.0 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.0 0.0 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.0 0.1 GO:0000012 single strand break repair(GO:0000012)
0.0 0.2 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.0 0.2 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.0 GO:1902809 regulation of skeletal muscle fiber differentiation(GO:1902809)
0.0 0.0 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0071148 TEAD-1-YAP complex(GO:0071148) TEAD-2-YAP complex(GO:0071149)
0.3 0.9 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.2 0.7 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.2 0.5 GO:0045203 intrinsic component of cell outer membrane(GO:0031230) integral component of cell outer membrane(GO:0045203)
0.1 1.6 GO:0032009 early phagosome(GO:0032009)
0.1 0.5 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.1 1.0 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 0.4 GO:0043293 apoptosome(GO:0043293)
0.1 0.8 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 0.3 GO:0032044 DSIF complex(GO:0032044)
0.1 0.7 GO:0071821 FANCM-MHF complex(GO:0071821)
0.1 0.1 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.1 0.3 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.2 GO:0098830 presynaptic endosome(GO:0098830)
0.1 0.2 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 0.2 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.1 0.4 GO:0036449 microtubule minus-end(GO:0036449)
0.1 0.2 GO:0070876 SOSS complex(GO:0070876)
0.1 1.3 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 0.3 GO:0030478 actin cap(GO:0030478)
0.1 0.2 GO:0005760 gamma DNA polymerase complex(GO:0005760)
0.1 0.6 GO:0071564 npBAF complex(GO:0071564)
0.1 0.2 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.1 0.2 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 0.9 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.1 0.5 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 1.0 GO:0043196 varicosity(GO:0043196)
0.0 0.2 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 0.1 GO:0034667 integrin alpha3-beta1 complex(GO:0034667)
0.0 1.1 GO:0000145 exocyst(GO:0000145)
0.0 0.3 GO:0035748 myelin sheath abaxonal region(GO:0035748)
0.0 0.5 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.3 GO:0070449 elongin complex(GO:0070449)
0.0 0.5 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.2 GO:0020016 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.0 1.8 GO:0032590 dendrite membrane(GO:0032590)
0.0 0.4 GO:0001940 male pronucleus(GO:0001940)
0.0 0.2 GO:0097149 centralspindlin complex(GO:0097149)
0.0 0.2 GO:0097422 tubular endosome(GO:0097422)
0.0 0.3 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 1.4 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.1 GO:0060187 cell pole(GO:0060187)
0.0 0.2 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.2 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0 0.3 GO:0032059 bleb(GO:0032059)
0.0 0.3 GO:0071437 invadopodium(GO:0071437)
0.0 0.1 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.2 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.0 0.5 GO:0001741 XY body(GO:0001741)
0.0 0.5 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 0.4 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.9 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.1 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.1 GO:1990032 parallel fiber(GO:1990032) AIP1-IRE1 complex(GO:1990597)
0.0 0.8 GO:0032589 neuron projection membrane(GO:0032589)
0.0 0.2 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.2 GO:0001739 sex chromatin(GO:0001739)
0.0 0.3 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.1 GO:0002079 inner acrosomal membrane(GO:0002079)
0.0 0.2 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.3 GO:0032279 asymmetric synapse(GO:0032279)
0.0 0.8 GO:0097440 apical dendrite(GO:0097440)
0.0 0.8 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.2 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.9 GO:0031201 SNARE complex(GO:0031201)
0.0 0.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.2 GO:0031010 ISWI-type complex(GO:0031010)
0.0 0.1 GO:0070847 core mediator complex(GO:0070847)
0.0 0.1 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 1.7 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.2 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.1 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.0 0.2 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.2 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.8 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.0 GO:0097454 Schwann cell microvillus(GO:0097454)
0.0 0.3 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.9 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.1 GO:0070522 ERCC4-ERCC1 complex(GO:0070522)
0.0 0.1 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.4 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.2 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 0.1 GO:0090576 RNA polymerase III transcription factor complex(GO:0090576)
0.0 0.0 GO:0033647 host intracellular organelle(GO:0033647) host intracellular membrane-bounded organelle(GO:0033648)
0.0 0.1 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.0 0.1 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.1 GO:0042587 glycogen granule(GO:0042587)
0.0 0.0 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.1 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.3 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.1 GO:0033263 CORVET complex(GO:0033263)
0.0 0.8 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.0 GO:0097196 Shu complex(GO:0097196)
0.0 0.2 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.2 GO:0043194 axon initial segment(GO:0043194)
0.0 2.2 GO:0030027 lamellipodium(GO:0030027)
0.0 0.6 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.3 GO:0042629 mast cell granule(GO:0042629)
0.0 0.4 GO:0016235 aggresome(GO:0016235)
0.0 0.1 GO:0043656 host cell cytoplasm(GO:0030430) host intracellular part(GO:0033646) host cell cytoplasm part(GO:0033655) intracellular region of host(GO:0043656)
0.0 0.1 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.0 0.0 GO:0005846 nuclear cap binding complex(GO:0005846)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.3 1.0 GO:1902379 chemoattractant activity involved in axon guidance(GO:1902379)
0.3 0.9 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.3 2.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.2 0.7 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.2 0.8 GO:0070644 vitamin D response element binding(GO:0070644)
0.2 1.1 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 0.8 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.1 0.4 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.1 0.6 GO:0005042 netrin receptor activity(GO:0005042)
0.1 0.7 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.1 0.8 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.1 0.3 GO:0052743 inositol tetrakisphosphate phosphatase activity(GO:0052743)
0.1 0.3 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 0.4 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 0.5 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.1 0.4 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 0.5 GO:0097016 L27 domain binding(GO:0097016)
0.1 0.7 GO:0016901 oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.1 0.6 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.1 0.3 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.1 0.7 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.1 0.2 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.1 0.3 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.1 1.0 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 0.6 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 0.6 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.1 0.6 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.1 0.2 GO:2001070 starch binding(GO:2001070)
0.1 1.0 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 0.2 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.1 0.4 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.1 0.8 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.1 0.5 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.1 0.2 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.1 0.3 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 0.5 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1 1.2 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 0.6 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.1 0.2 GO:0001847 opsonin receptor activity(GO:0001847)
0.1 0.3 GO:0004994 somatostatin receptor activity(GO:0004994)
0.1 0.2 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.1 0.4 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 0.3 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.1 0.2 GO:0004021 L-alanine:2-oxoglutarate aminotransferase activity(GO:0004021) alanine-oxo-acid transaminase activity(GO:0047635)
0.1 0.2 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.1 0.4 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 0.2 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.1 0.5 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 0.2 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.1 0.3 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.1 0.4 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 1.4 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.2 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.6 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.1 GO:0043398 HLH domain binding(GO:0043398)
0.0 0.3 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 1.1 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.3 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.1 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 0.3 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.2 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.2 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.7 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.8 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.3 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.4 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.2 GO:1904288 BAT3 complex binding(GO:1904288)
0.0 0.3 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.2 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.2 GO:0030250 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.0 0.1 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 2.3 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.1 GO:0004827 proline-tRNA ligase activity(GO:0004827) threonine-tRNA ligase activity(GO:0004829)
0.0 0.3 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.1 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.9 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.6 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 1.2 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.2 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.0 0.5 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.7 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.6 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.2 GO:0043199 sulfate binding(GO:0043199)
0.0 0.4 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.5 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.2 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.0 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.0 0.2 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.2 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.8 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.2 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.2 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.2 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.4 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.3 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.1 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.0 0.2 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.1 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0 0.2 GO:0022821 calcium, potassium:sodium antiporter activity(GO:0008273) calcium:cation antiporter activity(GO:0015368) potassium ion antiporter activity(GO:0022821)
0.0 1.0 GO:0045182 translation regulator activity(GO:0045182)
0.0 0.4 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.1 GO:0070513 death domain binding(GO:0070513)
0.0 0.2 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.3 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.1 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.2 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.4 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.2 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 0.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.0 0.2 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.1 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.1 GO:0035403 calcium-dependent protein kinase C activity(GO:0004698) histone kinase activity (H3-T6 specific)(GO:0035403)
0.0 0.1 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.3 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.3 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.2 GO:0016778 diphosphotransferase activity(GO:0016778)
0.0 0.3 GO:0032183 SUMO binding(GO:0032183)
0.0 0.1 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 0.2 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 0.3 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.6 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.1 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.1 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 0.1 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 1.3 GO:0019208 phosphatase regulator activity(GO:0019208)
0.0 0.2 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.1 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 1.2 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.1 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.0 0.1 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.0 0.1 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.4 GO:0042054 histone methyltransferase activity(GO:0042054)
0.0 0.1 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.0 0.3 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.2 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.2 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.0 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.0 0.0 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 0.3 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.3 GO:0031489 myosin V binding(GO:0031489)
0.0 0.1 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.2 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 1.0 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.1 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.1 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.2 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.3 GO:0043394 proteoglycan binding(GO:0043394)
0.0 0.3 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.1 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.0 0.0 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.0 0.9 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.1 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.1 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 0.0 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.1 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 0.2 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.3 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.0 GO:0070012 oligopeptidase activity(GO:0070012)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 1.1 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.1 1.1 PID IL3 PATHWAY IL3-mediated signaling events
0.1 3.6 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 1.5 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 1.4 PID REELIN PATHWAY Reelin signaling pathway
0.0 1.1 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 1.3 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.6 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.8 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 1.1 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.9 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.4 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.7 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.8 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.4 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.1 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 0.8 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.4 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.8 PID BMP PATHWAY BMP receptor signaling
0.0 0.6 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.1 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 1.1 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.4 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.6 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.3 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.2 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.6 PID FGF PATHWAY FGF signaling pathway
0.0 0.2 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.0 PID EPO PATHWAY EPO signaling pathway
0.0 0.4 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.2 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.7 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.5 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.1 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.4 PID FOXO PATHWAY FoxO family signaling
0.0 0.1 PID IFNG PATHWAY IFN-gamma pathway
0.0 0.1 PID CD40 PATHWAY CD40/CD40L signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 1.3 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.1 1.4 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 0.7 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 0.8 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.1 1.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 1.0 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 0.5 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 1.3 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.7 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 1.3 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.4 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.6 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.7 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.3 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.9 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.5 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.6 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.3 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.8 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.4 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.5 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.3 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.5 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.2 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.1 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.2 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.3 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.6 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.4 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.5 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.2 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.6 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.7 REACTOME IL 3 5 AND GM CSF SIGNALING Genes involved in Interleukin-3, 5 and GM-CSF signaling
0.0 1.2 REACTOME NCAM SIGNALING FOR NEURITE OUT GROWTH Genes involved in NCAM signaling for neurite out-growth
0.0 0.3 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.3 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.6 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.2 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.1 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.1 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.3 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 0.3 REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0 0.6 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.1 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.2 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.1 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 0.1 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.2 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.2 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 1.1 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.5 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins