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GSE49485: Hypoxia transcriptome sequencing of rat brain.
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Results for Hbp1
Z-value: 0.66
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Transcription factors associated with Hbp1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Hbp1 | rn6_v1_chr6_-_51257625_51257625 | -0.20 | 7.4e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr7_+_20262680 Show fit | 0.29 |
ENSRNOT00000046378
|
similar to hypothetical protein 4930509O22 |
|
| chr8_-_104155775 Show fit | 0.28 |
ENSRNOT00000042885
|
60S ribosomal protein L31-like |
|
| chr14_-_46153212 Show fit | 0.23 |
ENSRNOT00000079269
|
NACHT and WD repeat domain containing 2 |
|
| chr17_-_32783427 Show fit | 0.22 |
ENSRNOT00000059921
|
serine (or cysteine) peptidase inhibitor, clade B, member 6b |
|
| chr2_+_149899836 Show fit | 0.21 |
ENSRNOT00000086481
|
similar to hypothetical protein C130079G13 |
|
| chr7_-_120882392 Show fit | 0.21 |
ENSRNOT00000056179
ENSRNOT00000056178 |
family with sequence similarity 227, member A |
|
| chr14_+_63405408 Show fit | 0.20 |
ENSRNOT00000086658
|
|
|
| chr16_+_35116440 Show fit | 0.19 |
ENSRNOT00000074353
|
|
|
| chr6_+_127941526 Show fit | 0.19 |
ENSRNOT00000033897
|
Ab1-233 |
|
| chr12_+_24148567 Show fit | 0.19 |
ENSRNOT00000077378
ENSRNOT00000045157 |
C-C motif chemokine ligand 24 |
Network of associatons between targets according to the STRING database.
First level regulatory network of Hbp1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.2 | GO:0051933 | amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935) |
| 0.1 | 0.2 | GO:0006713 | glucocorticoid catabolic process(GO:0006713) |
| 0.0 | 0.2 | GO:2000418 | positive regulation of eosinophil migration(GO:2000418) |
| 0.0 | 0.1 | GO:0002215 | defense response to nematode(GO:0002215) |
| 0.0 | 0.1 | GO:0019276 | UDP-N-acetylgalactosamine metabolic process(GO:0019276) |
| 0.0 | 0.1 | GO:0002296 | T-helper 1 cell lineage commitment(GO:0002296) |
| 0.0 | 0.1 | GO:0048003 | antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007) |
| 0.0 | 0.1 | GO:0035261 | external genitalia morphogenesis(GO:0035261) gall bladder development(GO:0061010) |
| 0.0 | 0.1 | GO:0033512 | L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512) |
| 0.0 | 0.1 | GO:0002803 | positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antibacterial peptide production(GO:0002803) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.2 | GO:1990454 | L-type voltage-gated calcium channel complex(GO:1990454) |
| 0.0 | 0.1 | GO:0036117 | hyaluranon cable(GO:0036117) |
| 0.0 | 0.1 | GO:0071914 | prominosome(GO:0071914) |
| 0.0 | 0.1 | GO:0000120 | RNA polymerase I transcription factor complex(GO:0000120) |
| 0.0 | 0.1 | GO:0009331 | glycerol-3-phosphate dehydrogenase complex(GO:0009331) |
| 0.0 | 0.1 | GO:0035867 | alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867) |
| 0.0 | 0.1 | GO:0072534 | perineuronal net(GO:0072534) |
| 0.0 | 0.1 | GO:0020005 | symbiont-containing vacuole membrane(GO:0020005) |
| 0.0 | 0.1 | GO:0070436 | Grb2-EGFR complex(GO:0070436) |
| 0.0 | 0.1 | GO:0005579 | membrane attack complex(GO:0005579) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.2 | GO:0003845 | 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845) |
| 0.0 | 0.2 | GO:1990226 | histone methyltransferase binding(GO:1990226) |
| 0.0 | 0.2 | GO:0048018 | receptor agonist activity(GO:0048018) |
| 0.0 | 0.1 | GO:0047237 | glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237) |
| 0.0 | 0.1 | GO:0052591 | sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591) |
| 0.0 | 0.1 | GO:0016212 | kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137) |
| 0.0 | 0.1 | GO:0000829 | inositol heptakisphosphate kinase activity(GO:0000829) |
| 0.0 | 0.1 | GO:0005136 | interleukin-4 receptor binding(GO:0005136) |
| 0.0 | 0.1 | GO:0023030 | MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030) |
| 0.0 | 0.1 | GO:0016726 | xanthine dehydrogenase activity(GO:0004854) oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor(GO:0016726) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.2 | PID CIRCADIAN PATHWAY | Circadian rhythm pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.1 | REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION | Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression |
| 0.0 | 0.1 | REACTOME VEGF LIGAND RECEPTOR INTERACTIONS | Genes involved in VEGF ligand-receptor interactions |
| 0.0 | 0.1 | REACTOME TRYPTOPHAN CATABOLISM | Genes involved in Tryptophan catabolism |