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GSE49485: Hypoxia transcriptome sequencing of rat brain.
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Results for Gfi1_Gfi1b
Z-value: 0.44
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Transcription factors associated with Gfi1_Gfi1b
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Gfi1b | rn6_v1_chr3_-_7203420_7203420 | -0.32 | 6.0e-01 | Click! |
| Gfi1 | rn6_v1_chr14_+_3058993_3058993 | -0.11 | 8.6e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr14_+_43694183 Show fit | 0.45 |
ENSRNOT00000046342
|
similar to ribosomal protein S23 |
|
| chr14_-_18745457 Show fit | 0.34 |
ENSRNOT00000003778
|
C-X-C motif chemokine ligand 1 |
|
| chr3_-_123119460 Show fit | 0.32 |
ENSRNOT00000028833
|
arginine vasopressin |
|
| chr17_-_22143324 Show fit | 0.29 |
ENSRNOT00000019361
|
endothelin 1 |
|
| chr1_-_227047290 Show fit | 0.26 |
ENSRNOT00000037226
|
membrane spanning 4-domains A15 |
|
| chr4_-_44136815 Show fit | 0.18 |
ENSRNOT00000086810
|
transcription factor EC |
|
| chr10_-_70871066 Show fit | 0.15 |
ENSRNOT00000015139
|
C-C motif chemokine ligand 3 |
|
| chr14_-_42221225 Show fit | 0.15 |
ENSRNOT00000036103
|
shisa family member 3 |
|
| chr8_-_55491152 Show fit | 0.15 |
ENSRNOT00000014965
|
rCG58364-like |
|
| chr8_-_55194692 Show fit | 0.14 |
ENSRNOT00000068366
|
similar to RIKEN cDNA 1110032A03 |
Network of associatons between targets according to the STRING database.
First level regulatory network of Gfi1_Gfi1b
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.3 | GO:0070948 | regulation of neutrophil mediated cytotoxicity(GO:0070948) regulation of neutrophil mediated killing of symbiont cell(GO:0070949) |
| 0.1 | 0.3 | GO:0031583 | phospholipase D-activating G-protein coupled receptor signaling pathway(GO:0031583) |
| 0.1 | 0.3 | GO:0002125 | maternal aggressive behavior(GO:0002125) |
| 0.1 | 0.3 | GO:2000503 | positive regulation of natural killer cell chemotaxis(GO:2000503) |
| 0.1 | 0.2 | GO:0002188 | translation reinitiation(GO:0002188) |
| 0.0 | 0.1 | GO:0070173 | regulation of enamel mineralization(GO:0070173) |
| 0.0 | 0.1 | GO:0090158 | endoplasmic reticulum membrane organization(GO:0090158) |
| 0.0 | 0.1 | GO:0060160 | negative regulation of dopamine receptor signaling pathway(GO:0060160) |
| 0.0 | 0.1 | GO:0002018 | angiotensin maturation(GO:0002003) renin-angiotensin regulation of aldosterone production(GO:0002018) |
| 0.0 | 0.1 | GO:0002572 | pro-T cell differentiation(GO:0002572) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.3 | GO:0048237 | rough endoplasmic reticulum lumen(GO:0048237) |
| 0.0 | 0.1 | GO:0014701 | junctional sarcoplasmic reticulum membrane(GO:0014701) |
| 0.0 | 0.1 | GO:0033256 | I-kappaB/NF-kappaB complex(GO:0033256) |
| 0.0 | 0.1 | GO:0000214 | tRNA-intron endonuclease complex(GO:0000214) |
| 0.0 | 0.1 | GO:0005947 | mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) |
| 0.0 | 0.1 | GO:0042788 | polysomal ribosome(GO:0042788) |
| 0.0 | 0.0 | GO:0098982 | glycine-gated chloride channel complex(GO:0016935) GABA-ergic synapse(GO:0098982) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.3 | GO:0031893 | vasopressin receptor binding(GO:0031893) |
| 0.1 | 0.3 | GO:0031708 | endothelin B receptor binding(GO:0031708) |
| 0.1 | 0.3 | GO:0031726 | CCR1 chemokine receptor binding(GO:0031726) |
| 0.0 | 0.3 | GO:0045236 | CXCR chemokine receptor binding(GO:0045236) |
| 0.0 | 0.1 | GO:0001591 | dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591) |
| 0.0 | 0.1 | GO:0019767 | IgE receptor activity(GO:0019767) |
| 0.0 | 0.1 | GO:0070905 | serine binding(GO:0070905) |
| 0.0 | 0.1 | GO:0003922 | GMP synthase activity(GO:0003921) GMP synthase (glutamine-hydrolyzing) activity(GO:0003922) |
| 0.0 | 0.1 | GO:0004731 | purine-nucleoside phosphorylase activity(GO:0004731) |
| 0.0 | 0.1 | GO:0086057 | voltage-gated calcium channel activity involved in bundle of His cell action potential(GO:0086057) |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.7 | REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
| 0.0 | 0.3 | REACTOME TRANSPORT OF ORGANIC ANIONS | Genes involved in Transport of organic anions |