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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Fosl2_Bach2

Z-value: 0.92

Motif logo

Transcription factors associated with Fosl2_Bach2

Gene Symbol Gene ID Gene Info
ENSRNOG00000052357 FOS like 2, AP-1 transcription factor subunit
ENSRNOG00000006170 BTB domain and CNC homolog 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Bach2rn6_v1_chr5_+_47546014_47546014-0.721.7e-01Click!
Fosl2rn6_v1_chr6_-_25616995_25616995-0.622.7e-01Click!

Activity profile of Fosl2_Bach2 motif

Sorted Z-values of Fosl2_Bach2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_187863503 0.85 ENSRNOT00000093036
ENSRNOT00000026705
ENSRNOT00000082174
lamin A/C
chr10_-_82229140 0.70 ENSRNOT00000004400
epsin 3
chr10_-_90312386 0.65 ENSRNOT00000028445
solute carrier family 4 member 1
chr7_+_28654733 0.55 ENSRNOT00000006174
pro-melanin-concentrating hormone
chr1_+_198690794 0.53 ENSRNOT00000023999
zinc finger protein 771
chr1_-_24191908 0.51 ENSRNOT00000061157
serum/glucocorticoid regulated kinase 1
chr10_-_104575890 0.50 ENSRNOT00000050223
H3 histone family member 3B
chr17_+_6909728 0.48 ENSRNOT00000061231
hypothetical protein LOC681410
chr3_+_147609095 0.47 ENSRNOT00000041456
sulfiredoxin 1
chr1_+_218466289 0.46 ENSRNOT00000017948
MAS related GPR family member F
chr8_+_48571323 0.44 ENSRNOT00000059776
coiled-coil domain containing 153
chr20_+_5008508 0.43 ENSRNOT00000001153
von Willebrand factor A domain containing 7
chr7_+_59200918 0.41 ENSRNOT00000085073
protein tyrosine phosphatase, receptor type, R
chr1_+_199941161 0.41 ENSRNOT00000027616
Bcl2-associated athanogene 3
chr4_+_33638709 0.40 ENSRNOT00000009888
ENSRNOT00000034719
ENSRNOT00000052333
tachykinin, precursor 1
chr1_-_87191588 0.39 ENSRNOT00000027998
rCG54286-like
chr1_+_220826560 0.35 ENSRNOT00000027891
FOS like 1, AP-1 transcription factor subunit
chr8_+_117117430 0.35 ENSRNOT00000073247
glutathione peroxidase 1
chr8_+_75687100 0.35 ENSRNOT00000038677
annexin A2
chr13_+_89480058 0.32 ENSRNOT00000050804
cilia and flagella associated protein 126
chr20_+_5040337 0.32 ENSRNOT00000068435
chloride intracellular channel 1
chr10_+_35537977 0.31 ENSRNOT00000071917
ring finger protein 130
chr11_+_87435185 0.29 ENSRNOT00000002558
purinergic receptor P2X 6
chr13_-_50499060 0.29 ENSRNOT00000065347
ENSRNOT00000076924
ethanolamine kinase 2
chr3_+_1452644 0.26 ENSRNOT00000007949
interleukin 1 receptor antagonist
chr3_-_105512939 0.25 ENSRNOT00000011773
actin, alpha, cardiac muscle 1
chr1_+_105284753 0.25 ENSRNOT00000041950
solute carrier family 6 member 5
chr15_-_61564695 0.24 ENSRNOT00000068216
regulator of cell cycle
chr1_+_89008117 0.24 ENSRNOT00000028401
heat shock protein family B (small) member 6
chr20_-_3818045 0.24 ENSRNOT00000091622
hydroxysteroid (17-beta) dehydrogenase 8
chr8_+_55178289 0.24 ENSRNOT00000059127
crystallin, alpha B
chr1_+_72636959 0.22 ENSRNOT00000023489
interleukin 11
chr4_+_169147243 0.22 ENSRNOT00000011580
epithelial membrane protein 1
chr7_+_3355116 0.21 ENSRNOT00000030453
ENSRNOT00000061657
integrin subunit alpha 7
chr2_-_187854363 0.21 ENSRNOT00000092993
lamin A/C
chr1_-_88193346 0.21 ENSRNOT00000078600
immortalization up-regulated protein-like
chr7_+_144647587 0.21 ENSRNOT00000022398
homeo box C4
chr4_+_71740532 0.20 ENSRNOT00000023537
zyxin
chr15_-_34444244 0.20 ENSRNOT00000027612
cell death-inducing DFFA-like effector b
chr2_-_187863349 0.20 ENSRNOT00000084455
lamin A/C
chr1_-_101514547 0.20 ENSRNOT00000079633
protein phosphatase 1, regulatory subunit 15A
chr12_+_24761210 0.20 ENSRNOT00000002003
claudin 4
chr7_-_115981731 0.19 ENSRNOT00000036549
similar to secreted Ly6/uPAR related protein 2
chr14_-_10395047 0.19 ENSRNOT00000002936
glycerol-3-phosphate acyltransferase 3
chr1_-_124803363 0.18 ENSRNOT00000066380
Kruppel-like factor 13
chr16_+_23317953 0.18 ENSRNOT00000075287

chr5_+_59008933 0.18 ENSRNOT00000023060
carbonic anhydrase 9
chr11_+_27364916 0.18 ENSRNOT00000002151
BTB domain and CNC homolog 1
chr18_+_31094965 0.17 ENSRNOT00000026526
RELT-like 2
chr4_+_97657671 0.17 ENSRNOT00000075400
G protein subunit gamma 12
chr3_-_2444281 0.17 ENSRNOT00000013863
tubulin, beta 4B class IVb
chrM_+_7758 0.17 ENSRNOT00000046201
mitochondrially encoded ATP synthase 8
chr1_-_170318935 0.17 ENSRNOT00000024119
protein kinase C, delta binding protein
chr10_+_95706685 0.17 ENSRNOT00000004283
proteasome 26S subunit, non-ATPase 12
chr2_-_196207560 0.16 ENSRNOT00000028589
proteasome 26S subunit, non-ATPase 4
chr5_-_16706909 0.16 ENSRNOT00000011314
ribosomal protein S20
chr19_+_55381565 0.16 ENSRNOT00000018923
chromatin licensing and DNA replication factor 1
chr4_+_66276835 0.16 ENSRNOT00000007544
formation of mitochondrial complex V assembly factor 1
chr2_-_26135340 0.15 ENSRNOT00000074626
coagulation factor II (thrombin) receptor
chr3_+_2648885 0.15 ENSRNOT00000020339
ATP binding cassette subfamily A member 2
chr9_+_15166118 0.15 ENSRNOT00000020432
MyoD family inhibitor
chr1_-_89068348 0.15 ENSRNOT00000033621
uroplakin 1A
chr1_-_165680176 0.15 ENSRNOT00000025245
ENSRNOT00000082697
pleckstrin homology domain containing B1
chr3_-_10371240 0.15 ENSRNOT00000012075
argininosuccinate synthase 1
chr7_+_121480723 0.15 ENSRNOT00000065304
activating transcription factor 4
chrX_-_10413984 0.15 ENSRNOT00000039551
ENSRNOT00000091448
DEAD-box helicase 3, X-linked
chr14_+_34354503 0.15 ENSRNOT00000002941
neuromedin U
chr10_-_87232723 0.15 ENSRNOT00000015150
keratin 25
chr1_-_89560469 0.14 ENSRNOT00000079091
sodium voltage-gated channel beta subunit 1
chr7_+_70580198 0.14 ENSRNOT00000083472
ENSRNOT00000008941
DNA-damage inducible transcript 3
chr2_+_211337271 0.14 ENSRNOT00000045155
cytochrome c oxidase subunit 6B1
chr2_-_19808937 0.13 ENSRNOT00000044237
ATPase H+ transporting accessory protein 1 like
chr7_+_125576327 0.13 ENSRNOT00000016679
proline rich 5
chr2_+_93792601 0.13 ENSRNOT00000014701
ENSRNOT00000077311
fatty acid binding protein 4
chr4_-_155401480 0.13 ENSRNOT00000020735
apolipoprotein B mRNA editing enzyme catalytic subunit 1
chr19_-_37938857 0.13 ENSRNOT00000026730
solute carrier family 12 member 4
chr4_+_169161585 0.13 ENSRNOT00000079785
epithelial membrane protein 1
chr1_+_72635267 0.13 ENSRNOT00000090636
interleukin 11
chr7_-_93280009 0.13 ENSRNOT00000064877
sterile alpha motif domain containing 12
chr8_-_128665988 0.13 ENSRNOT00000050543
cysteine and serine rich nuclear protein 1
chr15_+_45834302 0.13 ENSRNOT00000051307
serpin family E member 3
chr1_+_91152635 0.13 ENSRNOT00000073438
dermokine-like
chr9_-_82154266 0.12 ENSRNOT00000024283
crystallin, beta A2
chr17_-_35037076 0.12 ENSRNOT00000090946
dual specificity phosphatase 22
chr4_-_157294047 0.12 ENSRNOT00000005601
enolase 2
chr20_+_3556975 0.12 ENSRNOT00000089417
discoidin domain receptor tyrosine kinase 1
chr10_+_10889488 0.12 ENSRNOT00000071746
UBA-like domain containing 1
chr18_-_27206777 0.12 ENSRNOT00000090569

chr3_+_22964230 0.12 ENSRNOT00000041813
ribosomal protein S20-like
chr5_+_161889342 0.12 ENSRNOT00000040481
ribosomal protein S20-like
chr1_+_89215266 0.12 ENSRNOT00000093612
ENSRNOT00000084799
dermokine
chr10_-_35716260 0.11 ENSRNOT00000004308
ENSRNOT00000059255
sequestosome 1
chr18_-_81539065 0.11 ENSRNOT00000021400
CNDP dipeptidase 2 (metallopeptidase M20 family)
chr18_-_74688551 0.11 ENSRNOT00000078016
solute carrier family 14 member 2
chr3_+_2642531 0.11 ENSRNOT00000081798
fucosyltransferase 7
chr4_-_97784842 0.11 ENSRNOT00000007698
growth arrest and DNA-damage-inducible, alpha
chr15_-_44860604 0.11 ENSRNOT00000018637
neurofilament medium
chrX_+_28593405 0.11 ENSRNOT00000071708
thymosin beta 4, X-linked
chr1_-_221917901 0.11 ENSRNOT00000092270
solute carrier family 22 member 12
chr17_+_12261102 0.11 ENSRNOT00000015525
nuclear factor, interleukin 3 regulated
chr7_-_144993652 0.11 ENSRNOT00000087748
integrin subunit alpha 5
chr11_-_83944763 0.11 ENSRNOT00000002358
proteasome 26S subunit, non-ATPase 2
chr9_+_20251521 0.11 ENSRNOT00000005535
gamma-enolase-like
chr11_-_84037938 0.11 ENSRNOT00000002327
ATP binding cassette subfamily F member 3
chr2_-_149417212 0.11 ENSRNOT00000018573
G protein-coupled receptor 87
chr17_+_10537365 0.10 ENSRNOT00000023651
clathrin, light chain B
chr5_+_137357674 0.10 ENSRNOT00000092813
similar to RIKEN cDNA 2610528J11
chr2_-_198339130 0.10 ENSRNOT00000028767
bolA family member 1
chr3_+_23290819 0.10 ENSRNOT00000018921
WD repeat domain 38
chr7_-_11648322 0.10 ENSRNOT00000026871
growth arrest and DNA-damage-inducible, beta
chr9_+_82436458 0.10 ENSRNOT00000026467
ENSRNOT00000081958
DnaJ heat shock protein family (Hsp40) member B2
chr1_+_225048149 0.10 ENSRNOT00000036454
LRRN4 C-terminal like
chr18_+_27923572 0.10 ENSRNOT00000008041
catenin alpha 1
chr5_+_153845094 0.09 ENSRNOT00000041600
sperm-tail PG-rich repeat containing 1
chr2_+_46980976 0.09 ENSRNOT00000083668
ENSRNOT00000082990
molybdenum cofactor synthesis 2
chr10_+_55712043 0.09 ENSRNOT00000010141
arachidonate lipoxygenase 3
chr2_-_148891900 0.09 ENSRNOT00000018488
siah E3 ubiquitin protein ligase 2
chr10_+_11338306 0.09 ENSRNOT00000033695
protein FAM100A-like
chr2_-_227207584 0.09 ENSRNOT00000065361
ENSRNOT00000080215
myozenin 2
chr3_-_91370167 0.09 ENSRNOT00000006291
proline rich 5 like
chr9_-_37231291 0.09 ENSRNOT00000016237
protein tyrosine phosphatase type IVA, member 1
chr4_+_176994129 0.09 ENSRNOT00000018734
cytidine monophosphate N-acetylneuraminic acid synthetase
chr1_-_198232344 0.09 ENSRNOT00000080988
aldolase, fructose-bisphosphate A
chr5_-_151824633 0.09 ENSRNOT00000043959
stratifin
chr8_+_69971778 0.09 ENSRNOT00000058007
ENSRNOT00000037941
ENSRNOT00000050649
multiple EGF-like-domains 11
chr1_+_78671121 0.09 ENSRNOT00000021310
adaptor-related protein complex 2, sigma 1 subunit
chr10_-_45923829 0.08 ENSRNOT00000035285
olfactory receptor 1462
chr13_+_105408179 0.08 ENSRNOT00000003378
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
chr14_+_89314176 0.08 ENSRNOT00000006765
uridine phosphorylase 1
chr1_+_212359177 0.08 ENSRNOT00000046314
zinc finger protein 511
chr14_-_7054548 0.08 ENSRNOT00000002973
nudix hydrolase 9
chr1_+_125124743 0.08 ENSRNOT00000021530
myotubularin related protein 10
chr10_-_29367865 0.08 ENSRNOT00000005304
tetratricopeptide repeat domain 1
chr2_-_197860699 0.08 ENSRNOT00000028740
extracellular matrix protein 1
chr1_-_225128740 0.08 ENSRNOT00000026897
retinal outer segment membrane protein 1
chr12_+_16988136 0.08 ENSRNOT00000078925
ENSRNOT00000036744
MICAL-like 2
chr10_+_49299125 0.08 ENSRNOT00000074853
trans-golgi network vesicle protein 23 homolog B
chr13_-_99287887 0.08 ENSRNOT00000004780
epoxide hydrolase 1
chr9_+_17817721 0.08 ENSRNOT00000086986
ENSRNOT00000026920
heat shock protein 90 alpha family class B member 1
chr13_+_92264231 0.08 ENSRNOT00000066509
ENSRNOT00000004716
spectrin, alpha, erythrocytic 1
chr1_-_266086299 0.08 ENSRNOT00000026609
CUE domain containing 2
chr11_+_73015387 0.08 ENSRNOT00000090978
glycoprotein V (platelet)
chr8_+_65733400 0.08 ENSRNOT00000089126
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr8_-_13513337 0.07 ENSRNOT00000071532
lysine-specific demethylase 4D
chr11_+_68198709 0.07 ENSRNOT00000003048
disrupted in renal carcinoma 2
chr5_+_168019058 0.07 ENSRNOT00000077202
TNF receptor superfamily member 9
chr12_+_7865938 0.07 ENSRNOT00000061229
ubiquitin-like 3
chr2_+_198040536 0.07 ENSRNOT00000028744
acidic nuclear phosphoprotein 32 family member E
chr11_+_82415995 0.07 ENSRNOT00000051772

chr13_-_100928811 0.07 ENSRNOT00000045326
calpain 2
chr13_+_88557860 0.07 ENSRNOT00000058547
SH2 domain containing 1B2
chr11_+_46179940 0.07 ENSRNOT00000088152
Trk-fused gene
chr19_+_52077109 0.07 ENSRNOT00000020225
oxidative stress induced growth inhibitor 1
chr11_+_30363280 0.07 ENSRNOT00000002885
superoxide dismutase 1, soluble
chr11_+_87374690 0.07 ENSRNOT00000086117
apoptosis inducing factor, mitochondria associated 3
chr10_-_89958805 0.07 ENSRNOT00000084266
membrane palmitoylated protein 3
chr19_-_39646693 0.07 ENSRNOT00000019104
proteasome 26S subunit, non-ATPase 7
chr4_-_147742114 0.07 ENSRNOT00000041464
EF-hand calcium binding domain 12
chr3_-_143192408 0.07 ENSRNOT00000006885
similar to cystatin E2
chr12_-_22006533 0.07 ENSRNOT00000059593
Uncharacterized protein C7orf61 homolog
chr8_+_5522739 0.07 ENSRNOT00000011507
matrix metallopeptidase 13
chr1_-_206394346 0.07 ENSRNOT00000038122
hypothetical LOC100302465
chrX_+_43625169 0.07 ENSRNOT00000086311
spermidine/spermine N1-acetyl transferase 1
chr13_+_83681322 0.07 ENSRNOT00000004206
mitochondrial pyruvate carrier 2
chr12_-_21746236 0.07 ENSRNOT00000001869
TSC22 domain family protein 4-like
chr9_-_19613360 0.07 ENSRNOT00000029593
regulator of calcineurin 2
chr1_-_219294147 0.07 ENSRNOT00000024601
glutathione S-transferase pi 1
chr4_+_78618737 0.07 ENSRNOT00000043790
diamine oxidase-like protein 2
chr20_+_295250 0.06 ENSRNOT00000000955
chloride intracellular channel 2
chr20_-_1099336 0.06 ENSRNOT00000071766
olfactory receptor-like protein-like
chr2_+_9526209 0.06 ENSRNOT00000021818
LysM domain containing 3
chr5_+_153835821 0.06 ENSRNOT00000077610
sperm-tail PG-rich repeat containing 1
chr6_+_72461977 0.06 ENSRNOT00000007887
ENSRNOT00000090716
adaptor-related protein complex 4, sigma 1 subunit
chr8_-_85840818 0.06 ENSRNOT00000013608
eukaryotic translation elongation factor 1 alpha 1
chr10_-_14703668 0.06 ENSRNOT00000024767
tryptase alpha/beta 1
chr4_+_45000973 0.06 ENSRNOT00000084736
ENSRNOT00000080880
suppression of tumorigenicity 7
chr13_-_90075144 0.06 ENSRNOT00000088884
SLAM family member 7
chr4_+_44573264 0.06 ENSRNOT00000080271
caveolin 2
chr9_+_71398710 0.06 ENSRNOT00000049411
cyclin Y-like 1
chr1_-_162533893 0.06 ENSRNOT00000016783
adipogenesis associated, Mth938 domain containing
chr3_-_71893600 0.06 ENSRNOT00000006787
ENSRNOT00000057685
tissue factor pathway inhibitor
chr10_+_59831241 0.05 ENSRNOT00000026596
transient receptor potential cation channel, subfamily V, member 3
chr1_+_87066289 0.05 ENSRNOT00000027645
calpain 12
chr5_+_135687538 0.05 ENSRNOT00000091664

chr2_-_45518502 0.05 ENSRNOT00000014627
heat shock protein family B (small) member 3
chr17_+_72160735 0.05 ENSRNOT00000038817
inter-alpha-trypsin inhibitor heavy chain 2
chr11_-_33003021 0.05 ENSRNOT00000084134
runt-related transcription factor 1
chr10_-_13168217 0.05 ENSRNOT00000087768
elongin B
chr15_+_36898195 0.05 ENSRNOT00000076266
poly (ADP-ribose) polymerase family, member 4
chr2_+_203200427 0.05 ENSRNOT00000020566
V-set domain containing T cell activation inhibitor 1
chr12_+_23463157 0.05 ENSRNOT00000044841
cut-like homeobox 1
chr11_+_47200029 0.05 ENSRNOT00000079598
neurexophilin and PC-esterase domain family, member 3
chr1_+_72810545 0.05 ENSRNOT00000092117
protein tyrosine phosphatase, receptor type, H
chr1_+_226258417 0.05 ENSRNOT00000081839

chrX_-_71121034 0.05 ENSRNOT00000076590
sorting nexin 12
chr12_+_30165694 0.05 ENSRNOT00000001211
argininosuccinate lyase
chr3_-_82756953 0.05 ENSRNOT00000044121
1-aminocyclopropane-1-carboxylate synthase homolog
chr3_-_22951711 0.05 ENSRNOT00000016876
ENSRNOT00000085981
proteasome subunit beta 7
chr7_+_13913929 0.05 ENSRNOT00000009833
coiled-coil domain containing 105
chr20_+_21316826 0.05 ENSRNOT00000000785
similar to RIKEN cDNA 1700040L02

Network of associatons between targets according to the STRING database.

First level regulatory network of Fosl2_Bach2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:1904178 sterol regulatory element binding protein import into nucleus(GO:0035105) negative regulation of adipose tissue development(GO:1904178)
0.1 0.6 GO:0010037 response to carbon dioxide(GO:0010037)
0.1 0.4 GO:2000645 negative regulation of receptor catabolic process(GO:2000645)
0.1 0.4 GO:0009609 response to symbiotic bacterium(GO:0009609)
0.1 0.5 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.1 0.4 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.1 0.5 GO:0060623 pericentric heterochromatin assembly(GO:0031508) regulation of chromosome condensation(GO:0060623)
0.1 0.3 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.1 0.4 GO:0007296 vitellogenesis(GO:0007296)
0.1 0.2 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.1 0.4 GO:0046878 positive regulation of saliva secretion(GO:0046878) positive regulation of glucocorticoid secretion(GO:2000851)
0.1 0.1 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.1 0.2 GO:1990790 response to glial cell derived neurotrophic factor(GO:1990790) cellular response to glial cell derived neurotrophic factor(GO:1990792)
0.1 0.2 GO:0000053 argininosuccinate metabolic process(GO:0000053)
0.1 0.2 GO:0072703 regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734) response to methyl methanesulfonate(GO:0072702) cellular response to methyl methanesulfonate(GO:0072703) response to environmental enrichment(GO:0090648) positive regulation of peptidyl-serine dephosphorylation(GO:1902310) response to methamphetamine hydrochloride(GO:1904313)
0.1 0.3 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.1 0.2 GO:1903575 cornified envelope assembly(GO:1903575)
0.1 0.4 GO:1903659 regulation of complement-dependent cytotoxicity(GO:1903659)
0.1 0.5 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.1 0.2 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163) regulation of DNA replication origin binding(GO:1902595)
0.1 0.2 GO:0099553 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.1 0.2 GO:0032377 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.1 0.3 GO:0036233 glycine import(GO:0036233)
0.0 0.1 GO:0033693 neurofilament bundle assembly(GO:0033693)
0.0 0.2 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.1 GO:2000015 regulation of determination of dorsal identity(GO:2000015)
0.0 0.2 GO:0046133 pyrimidine ribonucleoside catabolic process(GO:0046133)
0.0 0.5 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.2 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.1 GO:2000468 regulation of peroxidase activity(GO:2000468)
0.0 0.1 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 0.3 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.1 GO:0021966 corticospinal neuron axon guidance(GO:0021966)
0.0 0.1 GO:0071918 urea transmembrane transport(GO:0071918)
0.0 0.2 GO:0061621 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 0.1 GO:2001183 negative regulation of interleukin-12 secretion(GO:2001183)
0.0 0.1 GO:0051121 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.4 GO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
0.0 0.1 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.1 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.4 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0 0.1 GO:0042256 mature ribosome assembly(GO:0042256) protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.2 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 0.1 GO:0075509 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.0 0.3 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.1 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.0 0.1 GO:2000872 positive regulation of progesterone secretion(GO:2000872)
0.0 0.1 GO:0090187 positive regulation of pancreatic juice secretion(GO:0090187)
0.0 0.1 GO:0032919 spermine acetylation(GO:0032919)
0.0 0.1 GO:0009181 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.0 0.1 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.0 0.0 GO:0061152 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.0 0.1 GO:0010482 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.0 0.1 GO:0097332 response to antipsychotic drug(GO:0097332)
0.0 0.1 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.0 0.0 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.0 0.2 GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418)
0.0 0.2 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.1 GO:0072602 interleukin-4 secretion(GO:0072602)
0.0 0.2 GO:0032060 bleb assembly(GO:0032060)
0.0 0.2 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.2 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.0 0.0 GO:1901526 positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.0 0.1 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.1 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
0.0 0.1 GO:0015747 urate transport(GO:0015747)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.3 GO:0005638 lamin filament(GO:0005638)
0.1 0.5 GO:0097413 Lewy body(GO:0097413)
0.1 0.5 GO:0001740 Barr body(GO:0001740)
0.0 0.1 GO:0036488 CHOP-C/EBP complex(GO:0036488) CHOP-ATF3 complex(GO:1990622)
0.0 0.2 GO:0005927 muscle tendon junction(GO:0005927)
0.0 0.3 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.0 0.2 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.2 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.2 GO:0031094 platelet dense tubular network(GO:0031094)
0.0 0.5 GO:0005838 proteasome regulatory particle(GO:0005838)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.2 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.1 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.1 GO:0043293 apoptosome(GO:0043293)
0.0 0.2 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.1 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.2 GO:0070852 cell body fiber(GO:0070852)
0.0 0.1 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.0 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 0.0 GO:0005896 interleukin-6 receptor complex(GO:0005896)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.1 0.3 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.1 0.2 GO:0047025 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
0.1 0.5 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.1 0.3 GO:0004103 choline kinase activity(GO:0004103)
0.1 1.5 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.3 GO:0048019 receptor antagonist activity(GO:0048019)
0.0 0.4 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.2 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.3 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.2 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 1.1 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.6 GO:0015106 bicarbonate transmembrane transporter activity(GO:0015106)
0.0 0.1 GO:0002134 UTP binding(GO:0002134) sulfonylurea receptor binding(GO:0017098) pyrimidine ribonucleoside binding(GO:0032551)
0.0 0.1 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.1 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.0 0.3 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:0019809 spermidine binding(GO:0019809)
0.0 0.1 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.5 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.1 GO:0033592 RNA strand annealing activity(GO:0033592)
0.0 0.5 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.1 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 0.1 GO:0051373 FATZ binding(GO:0051373)
0.0 0.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.1 GO:0043262 adenosine-diphosphatase activity(GO:0043262) ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.1 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.2 GO:0042301 phosphate ion binding(GO:0042301)
0.0 0.1 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.0 0.2 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.0 GO:0016882 cyclo-ligase activity(GO:0016882)
0.0 0.5 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.3 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.1 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.1 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.0 0.2 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.1 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.0 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.1 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.1 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.1 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.0 GO:1990254 keratin filament binding(GO:1990254)
0.0 0.2 GO:0005247 voltage-gated chloride channel activity(GO:0005247)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.3 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.1 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.4 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.7 PID FOXO PATHWAY FoxO family signaling
0.0 0.3 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 1.3 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.3 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.5 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.3 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.0 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.3 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.7 REACTOME CDT1 ASSOCIATION WITH THE CDC6 ORC ORIGIN COMPLEX Genes involved in CDT1 association with the CDC6:ORC:origin complex
0.0 0.1 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport