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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for E2f1

Z-value: 1.00

Motif logo

Transcription factors associated with E2f1

Gene Symbol Gene ID Gene Info
ENSRNOG00000016708 E2F transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
E2f1rn6_v1_chr3_-_150062311_150062311-0.375.4e-01Click!

Activity profile of E2f1 motif

Sorted Z-values of E2f1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_33885495 1.43 ENSRNOT00000086633
syndecan 1
chr7_-_12221330 1.02 ENSRNOT00000042204
polo-like kinase 5
chr2_+_155555840 0.48 ENSRNOT00000080951

chr1_-_184188911 0.47 ENSRNOT00000055124
ENSRNOT00000014948
calcitonin-related polypeptide alpha
chr2_+_27107318 0.44 ENSRNOT00000019553
Rho guanine nucleotide exchange factor 26
chr18_-_63394690 0.44 ENSRNOT00000090078
ENSRNOT00000029431
centrosomal protein 76
chr11_+_89511191 0.43 ENSRNOT00000002510
minichromosome maintenance complex component 4
chr16_+_7303578 0.39 ENSRNOT00000025656
semaphorin 3G
chr16_-_73827488 0.38 ENSRNOT00000064070
ankyrin 1
chr10_-_56558487 0.38 ENSRNOT00000023256
solute carrier family 2 member 4
chr10_-_40953651 0.34 ENSRNOT00000063889
glycine receptor, alpha 1
chr10_+_72909550 0.33 ENSRNOT00000004540
protein phosphatase, Mg2+/Mn2+ dependent, 1D
chr10_-_18131562 0.33 ENSRNOT00000006676
T-cell leukemia, homeobox 3
chr19_+_14523554 0.30 ENSRNOT00000084271
ENSRNOT00000064731
minichromosome maintenance complex component 5
chr6_-_99783047 0.27 ENSRNOT00000009028
spectrin, beta, erythrocytic
chr20_+_4967194 0.27 ENSRNOT00000070846
LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated
chr1_-_31777070 0.26 ENSRNOT00000020711
solute carrier family 9 member A3
chr7_+_2435553 0.26 ENSRNOT00000065593
primase (DNA) subunit 1
chr4_+_145264462 0.26 ENSRNOT00000011246
bromodomain and PHD finger containing, 1
chr10_+_36098051 0.25 ENSRNOT00000083971
ADAM metallopeptidase with thrombospondin type 1 motif, 2
chr3_+_37599728 0.25 ENSRNOT00000090575
replication timing regulatory factor 1
chr10_-_40953467 0.25 ENSRNOT00000092189
glycine receptor, alpha 1
chr3_-_60795951 0.23 ENSRNOT00000002174
activating transcription factor 2
chr10_-_39373437 0.23 ENSRNOT00000058907
solute carrier family 22 member 5
chr17_+_88215834 0.23 ENSRNOT00000034098
G protein-coupled receptor 158
chr2_+_241029693 0.22 ENSRNOT00000033413
solute carrier family 39 member 8
chr14_+_87312203 0.22 ENSRNOT00000088032
adenylate cyclase 1
chr6_+_144291974 0.21 ENSRNOT00000035255
non-SMC condensin II complex, subunit G2
chr7_-_58219790 0.21 ENSRNOT00000067907
TBC1 domain family, member 15
chr7_-_93826665 0.21 ENSRNOT00000011344
TNF receptor superfamily member 11B
chr6_+_104340206 0.20 ENSRNOT00000058301
pleckstrin homology and coiled-coil domain containing D1
chr13_-_25262469 0.20 ENSRNOT00000019921
ring finger protein 152
chr6_-_111222858 0.20 ENSRNOT00000074707
transmembrane p24 trafficking protein 8
chr10_+_14373679 0.20 ENSRNOT00000022063
intraflagellar transport 140
chr5_-_109621170 0.20 ENSRNOT00000093007
ELAV like RNA binding protein 2
chr5_-_104980641 0.19 ENSRNOT00000071192
HAUS augmin-like complex, subunit 6
chr12_+_28381982 0.19 ENSRNOT00000076101
Williams-Beuren syndrome chromosome region 17
chr4_+_57019941 0.19 ENSRNOT00000011356
smoothened, frizzled class receptor
chr11_-_31847490 0.19 ENSRNOT00000061304
downstream neighbor of SON
chr1_+_214454090 0.19 ENSRNOT00000049448
tetraspanin 4
chr4_+_153217782 0.19 ENSRNOT00000015499
CECR2, histone acetyl-lysine reader
chrX_+_158835811 0.19 ENSRNOT00000071888
ENSRNOT00000080110
integrator complex subunit 6 like
chr5_+_154522119 0.18 ENSRNOT00000072618
E2F transcription factor 2
chr13_-_45068077 0.18 ENSRNOT00000004969
minichromosome maintenance complex component 6
chr10_-_72235888 0.18 ENSRNOT00000039481
zinc finger, HIT-type containing 3
chr4_+_57823411 0.18 ENSRNOT00000030462
ENSRNOT00000088235
serine-rich single-pass membrane protein 1
chr10_-_83128297 0.18 ENSRNOT00000082160
lysine acetyltransferase 7
chr5_+_24410863 0.17 ENSRNOT00000010591
tumor protein p53 inducible nuclear protein 1
chr20_-_8574082 0.17 ENSRNOT00000048845
MAM domain containing glycosylphosphatidylinositol anchor 1
chrX_+_15098904 0.17 ENSRNOT00000007367
ENSRNOT00000087033
RNA binding motif (RNP1, RRM) protein 3
chr14_+_33580541 0.17 ENSRNOT00000002905
phosphoribosyl pyrophosphate amidotransferase
chr9_-_9912276 0.17 ENSRNOT00000071515
tumor necrosis factor superfamily member 9
chr3_-_159802952 0.17 ENSRNOT00000011610
oxidative stress responsive serine-rich 1
chr16_-_74072541 0.17 ENSRNOT00000089722

chr1_+_228337767 0.17 ENSRNOT00000066247
PAT1 homolog 1, processing body mRNA decay factor
chr1_-_281756159 0.17 ENSRNOT00000013170
prolactin releasing hormone receptor
chr5_-_169658875 0.17 ENSRNOT00000015840
potassium voltage-gated channel subfamily A regulatory beta subunit 2
chr10_-_19652898 0.17 ENSRNOT00000009648
spindle apparatus coiled-coil protein 1
chr1_+_145770135 0.17 ENSRNOT00000015320
StAR-related lipid transfer domain containing 5
chr10_+_27973681 0.17 ENSRNOT00000004970
gamma-aminobutyric acid type A receptor beta 2 subunit
chr17_-_1085885 0.17 ENSRNOT00000026287
patched 1
chr8_-_132753145 0.17 ENSRNOT00000007467
ENSRNOT00000008172
similar to Solute carrier family 6 (neurotransmitter transporter), member 20
chr17_-_24182425 0.17 ENSRNOT00000024206
mitochondrial calcium uniporter regulator 1
chr3_-_5975734 0.17 ENSRNOT00000081376
vav guanine nucleotide exchange factor 2
chr10_-_82887301 0.16 ENSRNOT00000035894
integrin subunit alpha 3
chr4_-_57823283 0.16 ENSRNOT00000032772
ENSRNOT00000091255
transmembrane protein 209
chr7_+_53630621 0.16 ENSRNOT00000067011
ENSRNOT00000080598
cysteine and glycine-rich protein 2
chr18_-_16497886 0.16 ENSRNOT00000021624
regulation of nuclear pre-mRNA domain containing 1A
chr16_+_27399467 0.16 ENSRNOT00000065642
tolloid-like 1
chr7_+_78092037 0.16 ENSRNOT00000050753
regulating synaptic membrane exocytosis 2
chr4_-_148803988 0.16 ENSRNOT00000018101
Ras association domain family member 4
chr10_+_47282208 0.15 ENSRNOT00000057953
potassium voltage-gated channel subfamily J member 12
chr9_-_10757954 0.15 ENSRNOT00000075265
ubiquitin-like with PHD and ring finger domains 1
chr5_-_152762165 0.15 ENSRNOT00000022921
selenoprotein N
chr3_-_7422738 0.15 ENSRNOT00000088339
general transcription factor IIIC subunit 4
chr10_-_53037816 0.15 ENSRNOT00000057509
shisa family member 6
chr5_+_114940053 0.15 ENSRNOT00000012396
hook microtubule-tethering protein 1
chr1_+_263186235 0.15 ENSRNOT00000021876
cyclin and CBS domain divalent metal cation transport mediator 1
chr7_-_47586137 0.15 ENSRNOT00000006086
transmembrane and tetratricopeptide repeat containing 2
chr11_-_83867203 0.15 ENSRNOT00000002394
chordin
chr1_+_101541266 0.15 ENSRNOT00000028436
hydroxysteroid (17-beta) dehydrogenase 14
chr1_+_211423022 0.15 ENSRNOT00000029587
dihydropyrimidinase-like 4
chr1_+_221710670 0.15 ENSRNOT00000064798
mitogen activated protein kinase kinase kinase kinase 2
chr20_+_12944786 0.15 ENSRNOT00000048218
pericentrin
chr7_+_125649688 0.15 ENSRNOT00000017906
PHD finger protein 21B
chrX_-_75566481 0.14 ENSRNOT00000003714
zinc finger, DHHC-type containing 15
chr10_-_64202380 0.14 ENSRNOT00000008982
refilin B
chr4_-_68597586 0.14 ENSRNOT00000015921
similar to RIKEN cDNA E330009J07 gene
chr5_-_135663284 0.14 ENSRNOT00000087237
ENSRNOT00000066869
target of EGR1, member 1 (nuclear)
chr15_-_24056073 0.14 ENSRNOT00000015100
WD repeat and HMG-box DNA binding protein 1
chr5_-_129352886 0.14 ENSRNOT00000012088
cyclin-dependent kinase inhibitor 2C
chr1_+_241594565 0.14 ENSRNOT00000020123
amyloid beta precursor protein binding family A member 1
chrX_+_63343724 0.14 ENSRNOT00000076530
ENSRNOT00000008558
kelch-like family member 15
chrX_+_104882704 0.14 ENSRNOT00000079572
ENSRNOT00000074330
ENSRNOT00000082983
cleavage stimulation factor subunit 2
chr7_-_123088819 0.14 ENSRNOT00000056077

chr1_+_15412603 0.14 ENSRNOT00000051496
ENSRNOT00000067070
mitogen-activated protein kinase kinase kinase 5
chr13_+_97838361 0.14 ENSRNOT00000003641
consortin, connexin sorting protein
chr4_-_152380023 0.14 ENSRNOT00000012397
ELKS/RAB6-interacting/CAST family member 1
chr1_-_182140570 0.14 ENSRNOT00000060098
YTH domain containing 2
chr10_+_104582955 0.14 ENSRNOT00000009733
unkempt family zinc finger
chr2_+_58462949 0.13 ENSRNOT00000080618
NAD kinase 2, mitochondrial
chr1_+_167539036 0.13 ENSRNOT00000093112
ribonucleotide reductase catalytic subunit M1
chr1_+_101884019 0.13 ENSRNOT00000028650
transmembrane protein 143
chr6_+_99402360 0.13 ENSRNOT00000078498
zinc finger and BTB domain containing 1
chr5_-_133709712 0.13 ENSRNOT00000010201
forkhead box D2
chr9_+_10013854 0.13 ENSRNOT00000077653
ENSRNOT00000072033
KH-type splicing regulatory protein
chr10_-_57638485 0.13 ENSRNOT00000009468
DEAH-box helicase 33
chr14_+_82356916 0.13 ENSRNOT00000040229
stem-loop binding protein
chr1_+_198214797 0.13 ENSRNOT00000068543
T-box 6
chrX_+_31140960 0.13 ENSRNOT00000084395
ENSRNOT00000004494
motile sperm domain containing 2
chr17_-_10640548 0.13 ENSRNOT00000064274
SUMO-interacting motifs containing 1
chr1_+_85386470 0.13 ENSRNOT00000093332
ENSRNOT00000044326
pleckstrin homology and RhoGEF domain containing G2
chr8_+_114866768 0.13 ENSRNOT00000076731
WD repeat domain 82
chr10_+_11206226 0.13 ENSRNOT00000006979
transcription factor AP-4
chr12_+_38345456 0.12 ENSRNOT00000001685
CAP-GLY domain containing linker protein 1
chr4_-_82258765 0.12 ENSRNOT00000008523
homeo box A5
chrX_+_157353730 0.12 ENSRNOT00000080691
HAUS augmin-like complex, subunit 7
chr14_-_82287706 0.12 ENSRNOT00000080695
fibroblast growth factor receptor 3
chr16_+_20555395 0.12 ENSRNOT00000026652
growth differentiation factor 15
chr11_+_87522971 0.12 ENSRNOT00000043545
sphingomyelin phosphodiesterase 4
chr10_-_14373334 0.12 ENSRNOT00000022050
cramped chromatin regulator homolog 1
chr16_+_48863418 0.12 ENSRNOT00000029868
primase and DNA directed polymerase
chr8_-_48619592 0.12 ENSRNOT00000012534
ATP binding cassette subfamily G member 4
chr2_+_127686925 0.12 ENSRNOT00000086653
ENSRNOT00000016946
polo-like kinase 4
chr3_+_176865156 0.12 ENSRNOT00000019084
zinc finger CCCH-type and G-patch domain containing
chr3_-_163477715 0.12 ENSRNOT00000009517
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
chr3_+_124896618 0.12 ENSRNOT00000028888
CDP-diacylglycerol synthase 2
chr6_-_122897997 0.12 ENSRNOT00000057601
echinoderm microtubule associated protein like 5
chr19_-_19832812 0.12 ENSRNOT00000084657
poly(A) RNA polymerase D5, non-canonical
chr8_-_79119720 0.12 ENSRNOT00000086562
testis expressed 9
chr5_+_135663371 0.12 ENSRNOT00000024375
mutY DNA glycosylase
chr12_-_44279002 0.12 ENSRNOT00000064900
F-box protein 21
chr15_+_59216705 0.12 ENSRNOT00000030097
coiled-coil domain containing 122
chr8_-_13909061 0.12 ENSRNOT00000078372
ENSRNOT00000083011
centrosomal protein 295
chr2_+_184600721 0.12 ENSRNOT00000075823
glutamyl-tRNA amidotransferase subunit B
chr2_-_252691886 0.12 ENSRNOT00000068739
protein kinase cAMP-activated catalytic subunit beta
chr1_+_201981357 0.12 ENSRNOT00000027999
acyl-CoA dehydrogenase, short/branched chain
chr19_-_914880 0.12 ENSRNOT00000017127
chemokine-like factor
chr9_-_65387169 0.12 ENSRNOT00000051843
origin recognition complex, subunit 2
chr14_+_71533063 0.12 ENSRNOT00000004231
prominin 1
chr6_+_126636491 0.12 ENSRNOT00000089601
ubiquitin protein ligase E3 component n-recognin 7 (putative)
chr5_-_150609352 0.12 ENSRNOT00000074374
phosphatase and actin regulator 4
chr16_+_37177443 0.12 ENSRNOT00000014083
centrosomal protein 44
chr6_+_99433550 0.11 ENSRNOT00000079359
ENSRNOT00000008504
heat shock protein family A member 2
chr3_+_154507035 0.11 ENSRNOT00000017265
regulation of nuclear pre-mRNA domain containing 1B
chr7_-_123088279 0.11 ENSRNOT00000071998
transducer of ERBB2, 2
chr1_+_126749508 0.11 ENSRNOT00000015845
proprotein convertase subtilisin/kexin type 6
chr16_-_71319449 0.11 ENSRNOT00000029284
Fibroblast growth factor receptor 1
chr6_+_86651196 0.11 ENSRNOT00000034756
hypothetical LOC314168
chr20_+_13940877 0.11 ENSRNOT00000093587
calcineurin binding protein 1
chr1_-_190370499 0.11 ENSRNOT00000084389

chr13_-_48284990 0.11 ENSRNOT00000086928
SLIT-ROBO Rho GTPase activating protein 2
chr1_-_188713270 0.11 ENSRNOT00000082192
ENSRNOT00000065892
G protein-coupled receptor, class C, group 5, member B
chr7_-_12673659 0.11 ENSRNOT00000091650
ENSRNOT00000041277
ENSRNOT00000044865
polypyrimidine tract binding protein 1
chr7_+_37812831 0.11 ENSRNOT00000005910
BTG anti-proliferation factor 1
chr3_-_12007570 0.11 ENSRNOT00000060186
leucine rich repeat and sterile alpha motif containing 1
chr5_+_139783951 0.11 ENSRNOT00000081333
regulating synaptic membrane exocytosis 3
chr5_-_60559533 0.11 ENSRNOT00000092899
zinc finger and BTB domain containing 5
chr1_+_280103695 0.11 ENSRNOT00000065289
enolase family member 4
chr9_+_43049587 0.11 ENSRNOT00000021434
ENSRNOT00000079234
cyclin and CBS domain divalent metal cation transport mediator 4
chr5_+_47853818 0.11 ENSRNOT00000009228
ENSRNOT00000079656
caspase 8 associated protein 2
chr8_+_108958046 0.11 ENSRNOT00000079618
ENSRNOT00000066917
stromal antigen 1
chr1_-_163129641 0.11 ENSRNOT00000083055
calpain 5
chr11_-_61294022 0.11 ENSRNOT00000064385
spindle and centriole associated protein 1
chr1_+_173607101 0.11 ENSRNOT00000074636
tubby bipartite transcription factor
chr13_-_73704480 0.11 ENSRNOT00000005296
torsin 1A interacting protein 1
chr5_+_122647281 0.11 ENSRNOT00000066041
mesoderm induction early response 1, transcriptional regulator
chr17_+_36334147 0.10 ENSRNOT00000050261
E2F transcription factor 3
chrX_-_63291371 0.10 ENSRNOT00000082421
eukaryotic translation initiation factor 2 subunit gamma
chr10_-_31041626 0.10 ENSRNOT00000007267
LSM11, U7 small nuclear RNA associated
chr1_-_219682287 0.10 ENSRNOT00000026092
ras homolog family member D
chr1_+_264670841 0.10 ENSRNOT00000034814
ENSRNOT00000082412
SMC5-SMC6 complex localization factor 2
chr10_+_17421075 0.10 ENSRNOT00000047011
serine/threonine kinase 10
chr5_+_79382096 0.10 ENSRNOT00000085461
transmembrane protein 268
chr18_-_65768781 0.10 ENSRNOT00000016189
DNA polymerase iota
chr4_+_95884743 0.10 ENSRNOT00000008585
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1`
chr2_-_116413873 0.10 ENSRNOT00000010344
myoneurin
chr12_-_30033357 0.10 ENSRNOT00000001198
potassium channel tetramerization domain containing 7
chr7_+_140742418 0.10 ENSRNOT00000089211
peripherin
chr3_-_3691972 0.10 ENSRNOT00000061735
quiescin sulfhydryl oxidase 2
chr10_-_84881190 0.10 ENSRNOT00000073746
pyridoxamine 5'-phosphate oxidase
chr5_+_152721940 0.10 ENSRNOT00000039322
aurora kinase A and ninein interacting protein
chr11_-_27080701 0.10 ENSRNOT00000002180
listerin E3 ubiquitin protein ligase 1
chr7_+_97984862 0.10 ENSRNOT00000008508
ATPase family, AAA domain containing 2
chr10_-_15228235 0.10 ENSRNOT00000027121
WD repeat domain 90
chr7_+_2643288 0.10 ENSRNOT00000047241
timeless circadian clock
chr3_+_170354141 0.10 ENSRNOT00000005901
family with sequence similarity 210, member B
chr10_-_14324170 0.10 ENSRNOT00000035513
ENSRNOT00000090587
hematological and neurological expressed 1-like
chr2_-_219741886 0.10 ENSRNOT00000085122
solute carrier family 35 member A3
chr1_-_43884267 0.10 ENSRNOT00000024418
Cnksr family member 3
chr8_-_78655856 0.10 ENSRNOT00000081185
transcription factor 12
chr4_-_159482869 0.10 ENSRNOT00000088333
RAD51 associated protein 1
chr4_-_116278615 0.10 ENSRNOT00000020505
cytochrome P450, family 26, subfamily b, polypeptide 1
chr5_+_147185474 0.10 ENSRNOT00000000134
adenylate kinase 2
chr9_-_10757720 0.10 ENSRNOT00000083848
ubiquitin-like with PHD and ring finger domains 1
chr9_+_61823531 0.10 ENSRNOT00000070844
methionyl-tRNA synthetase 2, mitochondrial
chr2_-_124149621 0.10 ENSRNOT00000023448
ENSRNOT00000084825
ENSRNOT00000023437
nudix hydrolase 6
chr10_+_64360390 0.10 ENSRNOT00000010168
family with sequence similarity 57, member A
chr5_-_160619650 0.10 ENSRNOT00000089981
transmembrane protein 51
chr3_+_108944141 0.10 ENSRNOT00000034950
family with sequence similarity 98, member B

Network of associatons between targets according to the STRING database.

First level regulatory network of E2f1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.4 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.2 0.5 GO:0001983 baroreceptor response to increased systemic arterial blood pressure(GO:0001983)
0.1 0.7 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 0.6 GO:2000344 positive regulation of acrosome reaction(GO:2000344)
0.1 0.3 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.1 0.2 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.1 0.3 GO:0042891 antibiotic transport(GO:0042891)
0.1 0.2 GO:0036446 myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760)
0.1 0.2 GO:0042489 negative regulation of odontogenesis of dentin-containing tooth(GO:0042489)
0.1 0.2 GO:0006543 glutamine catabolic process(GO:0006543)
0.1 0.3 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.1 0.2 GO:0072720 response to dithiothreitol(GO:0072720)
0.1 0.2 GO:0045065 cytotoxic T cell differentiation(GO:0045065)
0.1 0.2 GO:0021997 epidermal cell fate specification(GO:0009957) response to chlorate(GO:0010157) neural plate axis specification(GO:0021997)
0.1 1.0 GO:0002347 response to tumor cell(GO:0002347)
0.1 0.2 GO:0014873 response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
0.1 0.4 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.1 0.2 GO:0016598 protein arginylation(GO:0016598)
0.0 0.1 GO:1900158 regulation of chondrocyte development(GO:0061181) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.0 0.1 GO:0048372 ventricular zone neuroblast division(GO:0021847) fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development(GO:0035607) lateral mesodermal cell fate commitment(GO:0048372) lateral mesodermal cell fate specification(GO:0048377) regulation of lateral mesodermal cell fate specification(GO:0048378)
0.0 0.1 GO:1990166 protein localization to site of double-strand break(GO:1990166)
0.0 0.2 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
0.0 0.1 GO:0046601 positive regulation of centriole replication(GO:0046601)
0.0 0.1 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.0 0.6 GO:0046599 regulation of centriole replication(GO:0046599)
0.0 0.2 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.1 GO:0060764 cell-cell signaling involved in mammary gland development(GO:0060764)
0.0 0.3 GO:0010216 maintenance of DNA methylation(GO:0010216)
0.0 0.1 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.0 0.2 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.1 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 0.1 GO:0003363 lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
0.0 0.4 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.1 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
0.0 0.1 GO:0042822 pyridoxal phosphate metabolic process(GO:0042822)
0.0 0.1 GO:0032066 nucleolus to nucleoplasm transport(GO:0032066)
0.0 0.1 GO:1904976 cellular response to bleomycin(GO:1904976)
0.0 0.1 GO:1902809 regulation of skeletal muscle fiber differentiation(GO:1902809)
0.0 0.1 GO:1904882 telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
0.0 0.1 GO:0006431 methionyl-tRNA aminoacylation(GO:0006431)
0.0 0.4 GO:1990403 embryonic brain development(GO:1990403)
0.0 0.2 GO:0070574 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0 0.1 GO:0002572 pro-T cell differentiation(GO:0002572)
0.0 0.2 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.2 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.0 0.1 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.0 0.1 GO:0042148 strand invasion(GO:0042148)
0.0 0.2 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.0 0.2 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0 0.1 GO:0010825 positive regulation of centrosome duplication(GO:0010825)
0.0 0.1 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.0 0.1 GO:0072139 glomerular parietal epithelial cell differentiation(GO:0072139)
0.0 0.1 GO:0060821 inactivation of X chromosome by DNA methylation(GO:0060821)
0.0 0.1 GO:1905245 regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902959) positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963) regulation of aspartic-type peptidase activity(GO:1905245) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.0 0.1 GO:0014043 negative regulation of neuron maturation(GO:0014043)
0.0 0.3 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.1 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.0 0.1 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.0 0.1 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.0 0.1 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781)
0.0 0.1 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.0 0.1 GO:0090172 microtubule cytoskeleton organization involved in homologous chromosome segregation(GO:0090172)
0.0 0.1 GO:1905168 positive regulation of double-strand break repair via homologous recombination(GO:1905168) replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.0 0.1 GO:0009992 cellular water homeostasis(GO:0009992)
0.0 0.1 GO:0006172 ADP biosynthetic process(GO:0006172)
0.0 0.1 GO:1901896 positive regulation of calcium-transporting ATPase activity(GO:1901896)
0.0 0.1 GO:0035986 senescence-associated heterochromatin focus assembly(GO:0035986)
0.0 0.4 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.1 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0 0.1 GO:0070827 chromatin maintenance(GO:0070827)
0.0 0.1 GO:0014826 vein smooth muscle contraction(GO:0014826)
0.0 0.1 GO:0019065 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.0 0.1 GO:0007354 zygotic determination of anterior/posterior axis, embryo(GO:0007354)
0.0 0.1 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.0 0.1 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0 0.2 GO:0001842 neural fold formation(GO:0001842)
0.0 0.1 GO:0036337 Fas signaling pathway(GO:0036337)
0.0 0.1 GO:0060014 granulosa cell differentiation(GO:0060014)
0.0 0.1 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.0 0.2 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.6 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.0 0.1 GO:0006713 glucocorticoid catabolic process(GO:0006713)
0.0 0.1 GO:1904354 negative regulation of telomere capping(GO:1904354)
0.0 0.1 GO:1903999 negative regulation of eating behavior(GO:1903999)
0.0 0.1 GO:0097338 response to clozapine(GO:0097338)
0.0 0.1 GO:0090625 mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.0 0.2 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.1 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.1 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 0.1 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.0 0.2 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.0 0.1 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.0 0.3 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.0 0.1 GO:0043570 maintenance of DNA repeat elements(GO:0043570)
0.0 0.1 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.5 GO:0044381 glucose import in response to insulin stimulus(GO:0044381)
0.0 0.1 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.1 GO:2000327 positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
0.0 0.1 GO:0031053 primary miRNA processing(GO:0031053)
0.0 0.1 GO:0046351 disaccharide biosynthetic process(GO:0046351)
0.0 0.2 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.1 GO:1901994 negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.0 0.1 GO:0072697 protein localization to cell cortex(GO:0072697)
0.0 0.2 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.0 GO:0010045 response to nickel cation(GO:0010045)
0.0 0.2 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.0 0.1 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.0 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.0 0.1 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.0 GO:0071930 negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.0 0.1 GO:0035188 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.0 0.1 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.0 0.1 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.0 0.1 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.0 0.2 GO:0035376 sterol import(GO:0035376) cholesterol import(GO:0070508)
0.0 0.3 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.0 0.3 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.1 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.1 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.0 0.1 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.0 0.1 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.1 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.1 GO:0002326 B cell lineage commitment(GO:0002326)
0.0 0.1 GO:0072675 osteoclast fusion(GO:0072675)
0.0 0.0 GO:0015864 pyrimidine nucleoside transport(GO:0015864)
0.0 0.1 GO:0031937 positive regulation of chromatin silencing(GO:0031937)
0.0 0.1 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.0 0.2 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.1 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.1 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 0.1 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.0 0.1 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.2 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.0 0.0 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.1 GO:0046061 dATP catabolic process(GO:0046061)
0.0 0.1 GO:0070417 cellular response to cold(GO:0070417)
0.0 0.1 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 0.1 GO:0044691 tooth eruption(GO:0044691)
0.0 0.2 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.1 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 0.1 GO:0089700 protein kinase D signaling(GO:0089700)
0.0 0.1 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.1 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.0 0.1 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.2 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.2 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.0 0.0 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 0.1 GO:0071494 cellular response to UV-C(GO:0071494)
0.0 0.0 GO:0045054 constitutive secretory pathway(GO:0045054)
0.0 0.1 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.1 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.1 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 0.0 GO:0061744 motor behavior(GO:0061744)
0.0 0.1 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.0 0.1 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.0 0.1 GO:0032439 endosome localization(GO:0032439)
0.0 0.0 GO:0048341 apoptotic process involved in outflow tract morphogenesis(GO:0003275) paraxial mesoderm formation(GO:0048341) negative regulation of lymphangiogenesis(GO:1901491) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
0.0 0.1 GO:0072423 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)
0.0 0.4 GO:0030517 negative regulation of axon extension(GO:0030517)
0.0 0.0 GO:1905071 proepicardium development(GO:0003342) septum transversum development(GO:0003343) occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075)
0.0 0.1 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.1 GO:0000492 small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.0 0.0 GO:0019676 ammonia assimilation cycle(GO:0019676)
0.0 0.1 GO:0006353 DNA-templated transcription, termination(GO:0006353)
0.0 0.1 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.0 0.1 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 0.1 GO:2000781 positive regulation of double-strand break repair(GO:2000781)
0.0 0.1 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.0 GO:0015960 diadenosine polyphosphate biosynthetic process(GO:0015960) diadenosine tetraphosphate metabolic process(GO:0015965) diadenosine tetraphosphate biosynthetic process(GO:0015966)
0.0 0.1 GO:0050434 positive regulation of viral transcription(GO:0050434)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0042555 MCM complex(GO:0042555)
0.1 0.7 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 0.3 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.1 0.2 GO:0034667 integrin alpha3-beta1 complex(GO:0034667)
0.0 0.2 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.1 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.0 0.3 GO:0000796 condensin complex(GO:0000796)
0.0 0.3 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.1 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 0.2 GO:0070695 FHF complex(GO:0070695)
0.0 0.4 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.4 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.2 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.3 GO:0001940 male pronucleus(GO:0001940)
0.0 0.2 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.2 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.1 GO:0044299 C-fiber(GO:0044299)
0.0 0.1 GO:0098536 deuterosome(GO:0098536)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.1 GO:1990423 RZZ complex(GO:1990423)
0.0 0.2 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.0 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
0.0 0.1 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
0.0 0.3 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.1 GO:0071914 prominosome(GO:0071914)
0.0 0.3 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.1 GO:0036128 CatSper complex(GO:0036128)
0.0 0.2 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.1 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.1 GO:0035363 histone locus body(GO:0035363)
0.0 0.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.1 GO:0030690 Noc1p-Noc2p complex(GO:0030690)
0.0 0.1 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.1 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.2 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.6 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.1 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.0 GO:0032301 MutSalpha complex(GO:0032301)
0.0 0.8 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.1 GO:0031010 ISWI-type complex(GO:0031010)
0.0 0.1 GO:0070847 core mediator complex(GO:0070847)
0.0 0.1 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.1 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.0 GO:1990590 ATF1-ATF4 transcription factor complex(GO:1990590)
0.0 0.1 GO:0002079 inner acrosomal membrane(GO:0002079)
0.0 0.1 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.2 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.1 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.1 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.0 0.2 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.1 GO:0030893 meiotic cohesin complex(GO:0030893)
0.0 0.1 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.1 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.3 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.0 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0 0.2 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.1 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.0 GO:0005688 U6 snRNP(GO:0005688)
0.0 0.0 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.0 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.0 0.1 GO:0032300 mismatch repair complex(GO:0032300)
0.0 0.0 GO:0031308 intrinsic component of nuclear outer membrane(GO:0031308) integral component of nuclear outer membrane(GO:0031309)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0030977 taurine binding(GO:0030977)
0.1 0.3 GO:0042895 antibiotic transporter activity(GO:0042895)
0.1 0.4 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.3 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.1 0.4 GO:0003896 DNA primase activity(GO:0003896)
0.1 0.2 GO:0005119 smoothened binding(GO:0005119)
0.0 0.1 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0 0.1 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.0 0.6 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.1 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.0 0.1 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.0 0.1 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.0 0.2 GO:0000700 mismatch base pair DNA N-glycosylase activity(GO:0000700)
0.0 0.1 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.2 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0 0.1 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 0.1 GO:0071209 U7 snRNA binding(GO:0071209)
0.0 0.3 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.3 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.3 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.1 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.1 GO:0004825 methionine-tRNA ligase activity(GO:0004825)
0.0 0.2 GO:0005113 patched binding(GO:0005113)
0.0 0.2 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.2 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.9 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.1 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.1 GO:1990715 mRNA CDS binding(GO:1990715)
0.0 0.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0032142 single guanine insertion binding(GO:0032142)
0.0 0.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.1 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.0 0.1 GO:0008142 oxysterol binding(GO:0008142)
0.0 1.4 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.1 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.0 0.1 GO:0015292 uniporter activity(GO:0015292)
0.0 0.1 GO:0004736 pyruvate carboxylase activity(GO:0004736)
0.0 0.1 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.1 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.2 GO:0045545 syndecan binding(GO:0045545)
0.0 0.2 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 0.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.1 GO:0036033 mediator complex binding(GO:0036033)
0.0 0.1 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.0 0.1 GO:0055105 ubiquitin-protein transferase inhibitor activity(GO:0055105)
0.0 0.1 GO:0032551 UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
0.0 0.1 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.1 GO:0071253 connexin binding(GO:0071253)
0.0 0.1 GO:0031750 D3 dopamine receptor binding(GO:0031750)
0.0 0.1 GO:0032296 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0 0.0 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.1 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.0 0.1 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.1 GO:0032052 bile acid binding(GO:0032052)
0.0 0.3 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.1 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.0 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.1 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0 0.2 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.0 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.0 0.0 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.0 0.0 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.0 0.0 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.0 0.2 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.0 0.2 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.1 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.0 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.2 GO:0031005 filamin binding(GO:0031005)
0.0 0.0 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.1 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.1 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.1 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.1 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.1 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.1 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.3 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.1 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.1 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.0 0.1 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.0 0.1 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.1 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.1 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 1.0 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.3 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.1 GO:0032554 purine deoxyribonucleotide binding(GO:0032554)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.4 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.3 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.6 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.3 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.0 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 0.3 PID ATM PATHWAY ATM pathway
0.0 0.2 PID IL1 PATHWAY IL1-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 0.1 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.1 0.7 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.8 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.4 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.5 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.0 0.2 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.1 REACTOME LAGGING STRAND SYNTHESIS Genes involved in Lagging Strand Synthesis
0.0 0.7 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.3 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.3 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.2 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.2 REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the multiple-nucleotide patch replacement pathway
0.0 0.2 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.2 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.1 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.1 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.2 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.1 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.2 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits