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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Atf5

Z-value: 0.39

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Transcription factors associated with Atf5

Gene Symbol Gene ID Gene Info
ENSRNOG00000020060 activating transcription factor 5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Atf5rn6_v1_chr1_-_100810522_100810522-0.108.7e-01Click!

Activity profile of Atf5 motif

Sorted Z-values of Atf5 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_-_21345805 0.39 ENSRNOT00000081296
ENSRNOT00000007802
carbonic anhydrase 8
chr10_-_88551056 0.28 ENSRNOT00000032737
zinc finger protein 385C
chr5_-_150167077 0.21 ENSRNOT00000088493
ENSRNOT00000013761
ENSRNOT00000067349
ENSRNOT00000051097
ENSRNOT00000067189
erythrocyte membrane protein band 4.1
chr1_-_255815733 0.10 ENSRNOT00000047387
cytoplasmic polyadenylation element binding protein 3
chr7_+_79638046 0.09 ENSRNOT00000029419
zinc finger protein, multitype 2
chr10_+_84131495 0.09 ENSRNOT00000009986
homeo box B8
chr8_+_81766041 0.08 ENSRNOT00000032280
one cut homeobox 1
chr16_+_27399467 0.08 ENSRNOT00000065642
tolloid-like 1
chrX_-_29648359 0.07 ENSRNOT00000086721
ENSRNOT00000006777
glycoprotein m6b
chr3_-_11417546 0.07 ENSRNOT00000018776
lipocalin 2
chr1_-_7480825 0.07 ENSRNOT00000048754
phosphatase and actin regulator 2
chr11_-_31180616 0.07 ENSRNOT00000065535
ENSRNOT00000052033
ENSRNOT00000002812
synaptojanin 1
chr5_+_79055521 0.06 ENSRNOT00000010333
collagen type XXVII alpha 1 chain
chr7_-_142348232 0.06 ENSRNOT00000078848
polypeptide N-acetylgalactosaminyltransferase 6
chr3_-_80601410 0.06 ENSRNOT00000022841
autophagy related 13
chr20_-_14193690 0.06 ENSRNOT00000058237
beta-ureidopropionase 1
chr4_+_60549197 0.05 ENSRNOT00000071249
ENSRNOT00000075621
exocyst complex component 4
chr7_+_80750725 0.05 ENSRNOT00000079962
oxidation resistance 1
chr3_+_116899878 0.05 ENSRNOT00000090802
ENSRNOT00000066101
semaphorin 6D
chr8_-_131899023 0.05 ENSRNOT00000034690
zinc finger protein 445
chr9_-_45206427 0.05 ENSRNOT00000042227
AF4/FMR2 family, member 3
chr8_+_52751854 0.04 ENSRNOT00000072518
neurexophilin and PC-esterase domain family, member 1
chr9_-_60672246 0.04 ENSRNOT00000017761
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
chr6_-_100011226 0.04 ENSRNOT00000083286
ENSRNOT00000041442
MYC associated factor X
chr9_+_121802673 0.04 ENSRNOT00000086534
YES proto-oncogene 1, Src family tyrosine kinase
chr14_-_87701884 0.04 ENSRNOT00000079338
motile sperm domain containing 1
chr20_-_5020150 0.04 ENSRNOT00000001146
suppressor APC domain containing 1
chr19_+_9668186 0.04 ENSRNOT00000016563
CCR4-NOT transcription complex, subunit 1
chr7_-_118332577 0.04 ENSRNOT00000090370
RNA binding protein, fox-1 homolog 2
chr9_-_28972835 0.03 ENSRNOT00000086967
ENSRNOT00000079684
regulating synaptic membrane exocytosis 1
chr6_-_102472926 0.03 ENSRNOT00000079351
zinc finger FYVE-type containing 26
chr16_-_7007287 0.03 ENSRNOT00000041216
inter-alpha trypsin inhibitor, heavy chain 3
chr1_-_57815038 0.02 ENSRNOT00000075401
repulsive guidance molecule family member B
chr1_+_245237736 0.02 ENSRNOT00000035814
very low density lipoprotein receptor
chr2_+_188141350 0.02 ENSRNOT00000078913
gon-4 like
chr5_+_129052043 0.02 ENSRNOT00000013459
tetratricopeptide repeat protein 39A
chr9_+_49479023 0.02 ENSRNOT00000050922
ENSRNOT00000077111
POU class 3 homeobox 3
chr1_+_192379543 0.02 ENSRNOT00000078705
protein kinase C, beta
chrX_-_159841072 0.02 ENSRNOT00000001158
Rac/Cdc42 guanine nucleotide exchange factor 6
chr13_+_43818010 0.02 ENSRNOT00000005532
centrosomal protein of 170 kDa-like
chrX_+_5549419 0.02 ENSRNOT00000004676
FUN14 domain containing 1
chr15_-_51834030 0.02 ENSRNOT00000024895
cell cycle and apoptosis regulator 2
chr5_-_138462864 0.02 ENSRNOT00000011325
coiled-coil domain containing 30
chr8_+_117679278 0.02 ENSRNOT00000042114
ubiquinol-cytochrome c reductase core protein I
chr18_-_86279680 0.02 ENSRNOT00000006169
hypothetical protein LOC689166
chr3_+_172510874 0.01 ENSRNOT00000073634
negative elongation factor complex member C/D
chr13_-_94859390 0.01 ENSRNOT00000005467
ENSRNOT00000079763

chr1_+_106998623 0.01 ENSRNOT00000022383
solute carrier family 17 member 6
chr7_-_121943121 0.01 ENSRNOT00000046460
ribosomal protein L26, pseudogene 1
chr5_-_173209768 0.01 ENSRNOT00000045053
ATPase family, AAA domain containing 3A
chr9_-_16643182 0.01 ENSRNOT00000024266
cullin-7
chr9_-_63637677 0.01 ENSRNOT00000049259
SATB homeobox 2
chr6_+_27768943 0.01 ENSRNOT00000015820
kinesin family member 3C
chr13_-_89291371 0.01 ENSRNOT00000004181
Fc receptor-like B
chr4_-_129569470 0.01 ENSRNOT00000008893
ubiquitin-like modifier activating enzyme 3
chr19_+_34139997 0.01 ENSRNOT00000017867
Rho GTPase activating protein 10
chr1_+_200037749 0.01 ENSRNOT00000027630
inositol polyphosphate-5-phosphatase F
chr1_+_199495298 0.00 ENSRNOT00000086003
ENSRNOT00000026748
integrin subunit alpha D
chr5_+_151211342 0.00 ENSRNOT00000067939
AT hook, DNA binding motif, containing 1
chr20_+_1889652 0.00 ENSRNOT00000068508
ENSRNOT00000000996
olfactory receptor 1746
chr9_-_71788281 0.00 ENSRNOT00000020078
crystallin, gamma C
chr19_+_41631715 0.00 ENSRNOT00000022749
carbohydrate sulfotransferase 4

Network of associatons between targets according to the STRING database.

First level regulatory network of Atf5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0045900 negative regulation of translational elongation(GO:0045900)
0.0 0.1 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.0 0.1 GO:2000195 negative regulation of female gonad development(GO:2000195)
0.0 0.1 GO:0019483 beta-alanine biosynthetic process(GO:0019483)
0.0 0.1 GO:0051612 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.1 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.0 0.0 GO:0031632 positive regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031632)
0.0 0.1 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.0 0.4 GO:0006730 one-carbon metabolic process(GO:0006730)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.1 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)