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GSE80451: E.coli grown aerobically and anaerobically

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Results for NarL

Z-value: 0.27

Transcription factors associated with NarL

Gene Symbol Gene ID Gene Info
narL
narL NarL

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
narL-0.941.8e-02Click!

Activity profile of NarL motif

Sorted Z-values of NarL motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
ompW 0.60
ompW
outer membrane protein W
cydDC 0.52
cydC
cydD
glutathione / L-cysteine exporter - CydC subunit
glutathione / L-cysteine exporter - CydD subunit
dcuSR 0.34
dcuR
dcuS
DcuR transcriptional activator
DcuS sensory histidine kinase
hybOABCDEFG 0.26
hybG
hybF
hybE
hybD
hybC
hybB
hybA
hybO
hydrogenase 2 accessory protein
protein involved with the maturation of hydrogenases 1 and 2
hydrogenase 2-specific chaperone
predicted maturation peptidase for hydrogenase 2
hydrogenase 2, large subunit
hydrogenase 2 - integral membrane subunit HybB
hydrogenase 2 - [Fe-S] binding, ferredoxin-type component HybA
hydrogenase 2, small subunit
ytfE 0.23
ytfE
iron-sulfur cluster repair protein YtfE
fdnGHI 0.22
fdnH
fdnI
fdnG
formate dehydrogenase N, β subunit
formate dehydrogenase N, γ subunit
formate dehydrogenase N, α subunit
dpiBA 0.20
dpiB
dpiA
DpiB sensory histidine kinase
DpiA transcriptional dual regulator
hcp-hcr 0.17
hcr
hcp
NADH oxidoreductase
hybrid-cluster protein
norVW 0.16
norW
norV
NADH:flavorubredoxin reductase
flavorubredoxin
ubiCA 0.12
ubiC
ubiA
chorismate lyase
4-hydroxybenzoate octaprenyltransferase
nrfABCDEFG 0.11
nrfF
nrfG
nrfD
nrfE
nrfB
nrfC
nrfA
activator of formate-dependent nitrite reductase complex
NrfG
formate dependent nitrite reductase - NrfD subunit
formate-dependent nitrite reductase; possible assembly function
formate-dependent nitrite reductase - penta-heme cytochrome c
formate-dependent nitrite reductase, 4Fe-4S subunit
formate dependent nitrite reductase - NrfA subunit
hyaABCDEF 0.11
hyaB
hyaC
hyaA
hyaF
hyaD
hyaE
hydrogenase 1, large subunit
hydrogenase 1, b-type cytochrome subunit
hydrogenase 1, small subunit
protein involved in nickel incorporation into hydrogenase 1 proteins
protein involved in processing of HyaA and HyaB proteins
protein involved in quality control of HyaA
nikABCDER 0.10
nikB
nikC
nikA
nikD
nikE
nikR
nickel ABC transporter - membrane subunit
nickel ABC transporter - membrane subunit
nickel ABC transporter - periplasmic binding protein
nickel ABC transporter - ATP binding subunit
nickel ABC transporter - ATP binding subunit
NikR DNA-binding transcriptional repressor, Ni-binding
dcuB-fumB 0.06
fumB
dcuB
fumarase B
dicarboxylate transporter DcuB
ynfEFGH-dmsD 0.06
ynfG
ynfF
ynfE
dmsD
ynfH
putative selenate reductase, predicted Fe-S subunit
putative selenate reductase, oxidoreductase subunit
putative selenate reductase, oxidoreductase subunit
DMS reductase maturation protein
putative selenate reductase, predicted membrane anchor subunit
fdhF 0.04
fdhF
formate dehydrogenase H
ydhYVWXUT 0.03
ydhY
ydhX
ydhW
ydhV
ydhU
ydhT
predicted 4Fe-4S ferredoxin-type protein
predicted 4Fe-4S ferredoxin-type protein
predicted protein
predicted oxidoreductase
predicted cytochrome
conserved protein
nirBDC-cysG 0.01
nirD
cysG
nirC
nirB
nitrite reductase, small subunit
siroheme synthase subunit
nitrite transporter NirC
nitrite reductase, large subunit
yeaR-yoaG 0.01
yoaG
yeaR
predicted protein
conserved protein

Network of associatons between targets according to the STRING database.

First level regulatory network of NarL

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0006857 sulfur amino acid transport(GO:0000101) oligopeptide transport(GO:0006857) oligopeptide transmembrane transport(GO:0035672)
0.1 0.3 GO:0046209 nitric oxide metabolic process(GO:0046209) nitric oxide catabolic process(GO:0046210)
0.1 0.3 GO:0019563 glycerol catabolic process(GO:0019563)
0.1 0.2 GO:0071310 cellular response to organic substance(GO:0071310)
0.1 0.3 GO:0015942 formate metabolic process(GO:0015942)
0.1 0.2 GO:0030091 protein repair(GO:0030091)
0.0 0.1 GO:0016485 protein processing(GO:0016485)
0.0 0.1 GO:0006744 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) ketone biosynthetic process(GO:0042181) quinone metabolic process(GO:1901661) quinone biosynthetic process(GO:1901663)
0.0 0.1 GO:0018198 peptidyl-cysteine modification(GO:0018198)
0.0 0.1 GO:0042330 chemotaxis(GO:0006935) taxis(GO:0042330)
0.0 0.3 GO:0000160 phosphorelay signal transduction system(GO:0000160)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0098567 periplasmic side of plasma membrane(GO:0098567)
0.0 0.2 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.6 GO:1904949 ATP-binding cassette (ABC) transporter complex(GO:0043190) ATPase dependent transmembrane transport complex(GO:0098533) ATPase complex(GO:1904949)
0.0 0.6 GO:0044462 cell outer membrane(GO:0009279) external encapsulating structure part(GO:0044462)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0005319 lipid transporter activity(GO:0005319)
0.1 0.3 GO:1902670 carbon dioxide binding(GO:1902670)
0.0 0.3 GO:0001140 transcriptional activator activity, bacterial-type RNA polymerase core promoter proximal region sequence-specific binding(GO:0001140) bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding(GO:0001216)
0.0 0.2 GO:0000156 phosphorelay response regulator activity(GO:0000156)
0.0 0.1 GO:0015099 nickel cation transmembrane transporter activity(GO:0015099)
0.0 0.1 GO:0004659 prenyltransferase activity(GO:0004659)
0.0 0.1 GO:0016151 nickel cation binding(GO:0016151)
0.0 0.2 GO:0004601 peroxidase activity(GO:0004601) oxidoreductase activity, acting on peroxide as acceptor(GO:0016684)
0.0 0.1 GO:0004333 fumarate hydratase activity(GO:0004333)
0.0 0.4 GO:0005506 iron ion binding(GO:0005506)