gadE-mdtEF | -0.453 | 5.389 | 0.969 | gadE (GadE DNA-binding transcriptional activator), mdtE (MdtEF-TolC multidrug efflux pump - membrane fusion protein), mdtF (MdtEF-TolC multidrug efflux pump - permease subunit) |
norVW | -0.182 | 5.909 | 0.957 | norW (NADH:flavorubredoxin reductase), norV (flavorubredoxin) |
gadW | -0.825 | 6.385 | 0.954 | gadW (GadW DNA-binding transcriptional dual regulator) |
cyoABCDE | 6.199 | 12.510 | 0.935 | cyoB (cytochrome bo terminal oxidase subunit I), cyoA (cytochrome bo terminal oxidase subunit II), cyoD (cytochrome bo terminal oxidase subunit IV), cyoC (cytochrome bo terminal oxidase subunit III), cyoE (heme O synthase) |
eno | 4.288 | 10.018 | 0.929 | eno (enolase) |
gadXW | -0.629 | 5.665 | 0.923 | gadW (GadW DNA-binding transcriptional dual regulator), gadX (GadX DNA-binding transcriptional dual regulator) |
edd-eda | 2.013 | 4.572 | 0.920 | edd (phosphogluconate dehydratase), eda (multifunctional 2-keto-3-deoxygluconate 6-phosphate aldolase and 2-keto-4-hydroxyglutarate aldolase and oxaloacetate decarboxylase) |
aroP | 3.737 | 6.744 | 0.918 | aroP (aromatic amino acid:H+ symporter AroP) |
gadX | -0.764 | 6.099 | 0.908 | gadX (GadX DNA-binding transcriptional dual regulator) |
ydeP | -0.351 | 5.750 | 0.905 | ydeP (acid resistance protein) |
dnaAN-recF | 2.129 | 4.581 | 0.899 | dnaA (chromosomal replication initiator protein DnaA; DNA-binding transcriptional dual regulator), dnaN (DNA polymerase III, β subunit), recF (ssDNA and dsDNA binding, ATP binding) |
gapA | 4.870 | 12.694 | 0.899 | gapA (glyceraldehyde 3-phosphate dehydrogenase) |
yciG | -0.960 | 7.056 | 0.899 | yciG (predicted protein) |
hflD-purB | 2.122 | 5.026 | 0.896 | hflD (lysogenization regulator), purB (adenylosuccinate lyase) |
ssrS | 13.699 | 14.191 | 0.890 | ssrS (6S RNA) |
ssrS-fau | 13.700 | 14.186 | 0.890 | ssrS (6S RNA), fau (5-formyltetrahydrofolate cyclo-ligase) |
zwf | 2.676 | 7.625 | 0.889 | zwf (glucose-6-phosphate dehydrogenase (NADP+)) |
asnC-mioC | 1.569 | 3.920 | 0.878 | asnC (AsnC DNA-binding transcriptional dual regulator), mioC (flavoprotein involved in biotin synthesis) |
yhiM | -0.671 | 7.268 | 0.874 | yhiM (inner membrane protein with a role in acid resistance) |
cadBA | -0.661 | 6.264 | 0.870 | cadA (lysine decarboxylase 1), cadB (lysine:cadaverine antiporter) |
yciGFE | -0.558 | 6.577 | 0.855 | yciG (predicted protein), yciF (conserved protein), yciE (conserved protein) |
hdeAB-yhiD | -0.343 | 6.320 | 0.854 | hdeB (HdeB monomer), yhiD (inner membrane protein YhiD), hdeA (HdeA monomer, chaperone active form) |
ydhYVWXUT | -0.027 | 4.805 | 0.852 | ydhY (predicted 4Fe-4S ferredoxin-type protein), ydhU (predicted cytochrome), ydhV (predicted oxidoreductase), ydhW (predicted protein), ydhX (predicted 4Fe-4S ferredoxin-type protein), ydhT (conserved protein) |
slp-dctR | 0.005 | 7.390 | 0.849 | dctR (predicted DNA-binding transcriptional regulator), slp (starvation lipoprotein) |
nikABCDER | 0.308 | 3.469 | 0.843 | nikB (nickel ABC transporter - membrane subunit), nikC (nickel ABC transporter - membrane subunit), nikD (nickel ABC transporter - ATP binding subunit), nikE (nickel ABC transporter - ATP binding subunit), nikA (nickel ABC transporter - periplasmic binding protein), nikR (NikR DNA-binding transcriptional repressor, Ni-binding) |
rpiR-alsBACE | 2.256 | 4.363 | 0.839 | alsE (allulose-6-phosphate 3-epimerase), rpiR (AlsR DNA-binding transcriptional repressor), alsB (D-allose ABC transporter - periplasmic binding protein), alsC (D-allose ABC transporter - membrane subunit), alsA (D-allose ABC transporter - ATP binding subunit) |
ptsHI-crr | 6.634 | 7.141 | 0.837 | ptsI (PTS enzyme I), crr (Enzyme IIAGlc; Crr), ptsH (HPr) |
xylAB | 0.785 | 6.318 | 0.834 | xylB (xylulokinase), xylA (xylose isomerase) |
hlyE | -0.926 | 7.230 | 0.832 | hlyE (hemolysin E) |
hypABCDE-fhlA | 0.464 | 3.804 | 0.831 | hypB (accessory protein for nickel incorporation into hydrogenase isoenzymes), hypA (accessory protein for nickel incorporation into hydrogenase 3), fhlA (FhlA transcriptional activator), hypC (HypC, protein involved in hydrogenase 3 maturation), hypE (hydrogenase maturation protein, carbamoyl dehydratase), hypD (HypD, scaffold protein for assembly of the Fe-(CN)2CO cofactor) |
aslB | -0.502 | 5.266 | 0.829 | aslB (predicted anaerobic sulfatase maturation enzyme) |
pepA | 2.797 | 5.906 | 0.827 | pepA (aminopeptidase A/I) |
acrAB | 3.167 | 7.986 | 0.821 | acrB (AcrAB-TolC multidrug efflux pump - permease subunit), acrA (AcrAB-TolC multidrug efflux pump - membrane fusion protein) |
purA | 4.387 | 9.837 | 0.810 | purA (adenylosuccinate synthetase) |
pfkA | 3.330 | 6.049 | 0.806 | pfkA (6-phosphofructokinase I) |
crfC-yjcZ | -0.137 | 4.247 | 0.804 | yjcZ (conserved protein), crfC (clamp-binding sister replication fork colocalization protein) |
gcvTHP | 2.807 | 9.325 | 0.804 | gcvT (aminomethyltransferase), gcvP (glycine decarboxylase), gcvH (glycine cleavage system H protein) |
yggE | 0.978 | 4.770 | 0.803 | yggE (conserved protein) |
hyaABCDEF | 1.041 | 6.252 | 0.802 | hyaE (protein involved in quality control of HyaA), hyaA (hydrogenase 1, small subunit), hyaD (protein involved in processing of HyaA and HyaB proteins), hyaB (hydrogenase 1, large subunit), hyaF (protein involved in nickel incorporation into hydrogenase 1 proteins), hyaC (hydrogenase 1, b-type cytochrome subunit) |
codBA | 1.283 | 4.103 | 0.794 | codA (cytosine deaminase), codB (cytosine transporter) |
hchA | -0.273 | 5.731 | 0.792 | hchA (amino acid deglycase Hsp31) |
atoDAEB | 0.015 | 6.067 | 0.789 | atoE (predicted short chain fatty acid transporter), atoB (acetyl-CoA acetyltransferase), atoA (acetyl-CoA:acetoacetyl-CoA transferase, β subunit), atoD (acetyl-CoA:acetoacetyl-CoA transferase, α subunit) |
fadL | 1.988 | 3.936 | 0.789 | fadL (long-chain fatty acid outer membrane porin; bacteriophage T2 receptor) |
glpFKX | 3.530 | 7.969 | 0.789 | glpF (glycerol channel GlpF), glpK (glycerol kinase), glpX (fructose 1,6-bisphosphatase II) |
asnC-mioC-mnmG | 2.112 | 5.129 | 0.788 | asnC (AsnC DNA-binding transcriptional dual regulator), mioC (flavoprotein involved in biotin synthesis), mnmG (protein involved in modification of U34 in tRNA) |
leuO | -0.222 | 6.056 | 0.787 | leuO (LeuO DNA-binding transcriptional dual regulator) |
otsBA | 1.193 | 4.017 | 0.780 | otsA (trehalose-6-phosphate synthase), otsB (trehalose-6-phosphate phosphatase) |
tktB | -0.009 | 4.625 | 0.778 | tktB (transketolase II) |
gltBDF | 4.285 | 14.862 | 0.773 | gltF (periplasmic protein), gltB (glutamate synthase, large subunit), gltD (glutamate synthase, small subunit) |
uxuAB | 1.674 | 5.800 | 0.770 | uxuA (D-mannonate dehydratase), uxuB (D-mannonate oxidoreductase) |
cvpA-purF-ubiX | 2.389 | 6.502 | 0.769 | purF (amidophosphoribosyl transferase), ubiX (3-octaprenyl-4-hydroxybenzoate carboxy-lyase partner protein), cvpA (membrane protein required for colicin V production) |
deoCABD | 3.827 | 4.300 | 0.768 | deoB (phosphopentomutase), deoC (deoxyribose-phosphate aldolase), deoD (purine nucleoside phosphorylase), deoA (thymidine phosphorylase / uracil phosphorylase) |
pdhR-aceEF-lpd | 5.413 | 9.472 | 0.767 | lpd (lipoamide dehydrogenase), pdhR (PdhR DNA-binding transcriptional dual regulator), aceF (pyruvate dehydrogenase, E2 subunit), aceE (subunit of E1p component of pyruvate dehydrogenase complex) |
araFGH | 1.830 | 6.271 | 0.767 | araG (arabinose ABC transporter - ATP binding subunit), araH (arabinose ABC transporter - membrane subunit), araF (arabinose ABC transporter - periplasmic binding protein) |
bglG | -0.932 | 6.778 | 0.765 | bglG (BglG transcriptional antiterminator) |
metNIQ | 3.795 | 10.196 | 0.763 | metN (L-methionine / D-methionine ABC transporter - ATP binding subunit), metQ (L-methionine / D-methionine ABC transporter - periplasmic binding protein), metI (L-methionine / D-methionine ABC transporter - membrane subunit) |
hypABCDE | 0.187 | 3.742 | 0.755 | hypB (accessory protein for nickel incorporation into hydrogenase isoenzymes), hypA (accessory protein for nickel incorporation into hydrogenase 3), hypC (HypC, protein involved in hydrogenase 3 maturation), hypE (hydrogenase maturation protein, carbamoyl dehydratase), hypD (HypD, scaffold protein for assembly of the Fe-(CN)2CO cofactor) |
lysC | 2.136 | 6.377 | 0.754 | lysC (aspartate kinase III) |
fabB | 3.184 | 4.478 | 0.754 | fabB (β-ketoacyl-ACP synthase I) |
dapD | 1.838 | 4.706 | 0.752 | dapD (tetrahydrodipicolinate succinylase) |
malZ | 1.694 | 5.808 | 0.752 | malZ (maltodextrin glucosidase) |
xylFGHR | 0.541 | 4.129 | 0.751 | xylG (xylose ABC transporter - ATP binding subunit), xylR (XylR transcriptional dual regulator), xylH (xylose ABC transporter - membrane subunit), xylF (xylose ABC transporter - periplasmic binding protein) |
betIBA | 2.604 | 4.660 | 0.750 | betB (betaine aldehyde dehydrogenase), betA (choline dehydrogenase), betI (BetI DNA-binding transcriptional repressor) |
araE-ygeA | 0.193 | 3.885 | 0.746 | araE (arabinose:H+ symporter), ygeA (predicted racemase) |
uidABC | 0.497 | 6.213 | 0.744 | uidA (β-D-glucuronidase), uidB (glucuronide:H+ symporter), uidC (outer membrane-associated protein) |
lysP | 1.782 | 4.489 | 0.741 | lysP (lysine:H+ symporter) |
gnd | 2.737 | 7.374 | 0.739 | gnd (6-phosphogluconate dehydrogenase, decarboxylating) |
yjjP | -0.229 | 5.580 | 0.738 | yjjP (predicted inner membrane structural protein) |
purHD | 2.539 | 10.518 | 0.737 | purD (phosphoribosylamine-glycine ligase), purH (AICAR transformylase/IMP cyclohydrolase) |
safA-ydeO | -0.854 | 7.323 | 0.736 | ydeO (YdeO DNA-binding transcriptional dual regulator), safA (two-component system connector protein) |
gdhA | 2.370 | 9.187 | 0.733 | gdhA (glutamate dehydrogenase) |
nfsB | 1.455 | 3.379 | 0.732 | nfsB (NAD(P)H nitroreductase NfsB) |
cbl | 1.504 | 5.483 | 0.730 | cbl (Cbl DNA-binding transcriptional activator) |
yhjC | -0.218 | 4.876 | 0.728 | yhjC (predicted DNA-binding transcriptional regulator) |
appY | -0.398 | 5.222 | 0.726 | appY (AppY DNA-binding transcriptional activator) |
exuT | 0.228 | 5.555 | 0.725 | exuT (hexuronate transporter) |
glpTQ | 2.189 | 9.815 | 0.725 | glpQ (glycerophosphoryl diester phosphodiesterase, periplasmic), glpT (glycerol-3-phosphate:phosphate antiporter) |
yeaR-yoaG | -0.544 | 8.523 | 0.725 | yeaR (conserved protein), yoaG (predicted protein) |
cydAB | 4.000 | 5.706 | 0.724 | cydA (cytochrome bd-I terminal oxidase subunit I), cydB (cytochrome bd-I terminal oxidase subunit II) |
trg | 0.114 | 6.161 | 0.720 | |
fecABCDE | 4.492 | 13.139 | 0.715 | fecB (ferric citrate ABC transporter - periplasmic binding protein), fecE (ferric citrate ABC transporter - ATP binding subunit), fecD (ferric citrate ABC transporter - membrane subunit), fecC (ferric citrate ABC transporter - membrane subunit), fecA (ferric citrate outer membrane porin FecA) |
araE | -0.226 | 5.450 | 0.715 | araE (arabinose:H+ symporter) |
ygfK-ssnA | -0.441 | 6.096 | 0.713 | ssnA (predicted chlorohydrolase/aminohydrolase), ygfK (predicted oxidoreductase, Fe-S subunit) |
purC | 2.491 | 8.988 | 0.711 | purC (phosphoribosylaminoimidazole-succinocarboxamide synthase) |
murQP | 0.841 | 2.297 | 0.708 | murP (N-acetylmuramic acid PTS permease / anhydro-N-acetylmuramic acid permease), murQ (N-acetylmuramic acid 6-phosphate etherase) |
nanCMS | -0.421 | 6.740 | 0.703 | nanC (N-acetylneuraminic acid outer membrane channel), nanS (probable 9-O-acetyl-N-acetylneuraminate esterase), nanM (N-acetylneuraminate mutarotase) |
dadAX | 4.322 | 5.416 | 0.703 | dadX (alanine racemase 2, PLP-binding), dadA (D-amino acid dehydrogenase) |
talA-tktB | 0.635 | 4.214 | 0.699 | talA (transaldolase A), tktB (transketolase II) |
carAB | 2.721 | 9.580 | 0.699 | carB (carbamoyl phosphate synthetase, β chain), carA (carbamoyl phosphate synthetase, α chain) |
rpoH | 4.559 | 5.433 | 0.694 | rpoH (RNA polymerase, sigma 32 (sigma H) factor) |
speAB | 3.752 | 5.005 | 0.694 | speA (arginine decarboxylase, biosynthetic), speB (agmatinase) |
purL | 1.816 | 8.406 | 0.690 | purL (phosphoribosylformylglycinamide synthetase) |
ynjI | -0.049 | 3.472 | 0.688 | ynjI (predicted inner membrane protein) |
malK-lamB-malM | 4.672 | 10.880 | 0.685 | malK (maltose ABC transporter - ATP binding subunit), lamB (maltose outer membrane porin / phage lambda receptor protein), malM (maltose regulon periplasmic protein) |
rtcBA | 0.243 | 6.003 | 0.683 | rtcB (RNA-splicing ligase RtcB), rtcA (RNA 3'-terminal phosphate cyclase) |
dapB | 1.429 | 3.752 | 0.682 | dapB (4-hydroxy-tetrahydrodipicolinate reductase) |
yciW | 1.260 | 5.876 | 0.675 | yciW (predicted oxidoreductase) |
purEK | 1.537 | 8.030 | 0.674 | purK (N5-carboxyaminoimidazole ribonucleotide synthetase), purE (N5-carboxyaminoimidazole ribonucleotide mutase) |
emrD | -0.412 | 6.640 | 0.673 | emrD (multidrug efflux pump EmrD) |
malS | 1.503 | 4.605 | 0.664 | malS (α-amylase) |