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PRJEB1986: zebrafish developmental stages transcriptome

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Results for rcor1+rcor2+rcor3

Z-value: 0.83

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Transcription factors associated with rcor1+rcor2+rcor3

Gene Symbol Gene ID Gene Info
ENSDARG00000004502 REST corepressor 3
ENSDARG00000008278 REST corepressor 2
ENSDARG00000031434 REST corepressor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
rcor2dr11_v1_chr7_-_24995631_249956400.681.5e-03Click!
rcor3dr11_v1_chr22_+_38276024_382760240.652.5e-03Click!
rcor1dr11_v1_chr17_-_29271359_292713590.522.3e-02Click!

Activity profile of rcor1+rcor2+rcor3 motif

Sorted Z-values of rcor1+rcor2+rcor3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_56095275 0.86 ENSDART00000154701
si:ch211-178n15.1
chr3_+_41917499 0.80 ENSDART00000028673
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr3_-_62527675 0.78 ENSDART00000155048
ENSDART00000064500
SRY (sex determining region Y)-box 9b
chr1_-_59571758 0.71 ENSDART00000193546
ENSDART00000167087
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1
chr7_+_21752168 0.68 ENSDART00000173641
lysine (K)-specific demethylase 6B, a
chr8_-_36554675 0.68 ENSDART00000132804
ENSDART00000078746
coiled-coil domain containing 157
chr11_+_14937904 0.68 ENSDART00000185103

chr17_+_1514711 0.67 ENSDART00000165641
v-akt murine thymoma viral oncogene homolog 1
chr22_+_569565 0.66 ENSDART00000037069
ubiquitin specific peptidase 49
chr5_+_22098591 0.64 ENSDART00000143676
zinc finger CCCH-type containing 12B
chr2_+_11685742 0.62 ENSDART00000138562
growth regulation by estrogen in breast cancer-like
chr17_+_41992054 0.59 ENSDART00000182878
ENSDART00000111537
kizuna centrosomal protein
chr22_+_10215558 0.59 ENSDART00000063274
potassium channel tetramerization domain containing 6a
chr2_+_30032303 0.58 ENSDART00000151841
RNA binding motif protein 33b
chr19_+_48060464 0.57 ENSDART00000123163
zgc:85936
chr25_-_37258653 0.57 ENSDART00000131076
ring finger and WD repeat domain 3
chr16_+_29043813 0.56 ENSDART00000122681
nestin
chr4_-_19693978 0.56 ENSDART00000100974
ENSDART00000040405
staphylococcal nuclease and tudor domain containing 1
chr12_+_8003872 0.55 ENSDART00000180300
ENSDART00000126661
Rho-related BTB domain containing 1
chr3_-_38777553 0.55 ENSDART00000193045
zinc finger protein 281a
chr7_+_51103416 0.53 ENSDART00000174236
collagen, type IV, alpha 5 (Alport syndrome)
chr4_-_64703 0.53 ENSDART00000167851

chr6_+_31684 0.53 ENSDART00000188853
ENSDART00000184553

chr19_+_7559901 0.53 ENSDART00000141189
pre-B-cell leukemia homeobox interacting protein 1a
chr8_+_29749017 0.52 ENSDART00000185144
mitogen-activated protein kinase 4
chr21_-_30787414 0.52 ENSDART00000012091
ribonucleotide reductase M1 polypeptide
chr10_-_36618674 0.52 ENSDART00000135302
remodeling and spacing factor 1b, tandem duplicate 1
chr20_-_32981053 0.51 ENSDART00000138708
neuroblastoma amplified sequence
chr22_-_11724563 0.51 ENSDART00000190796
ENSDART00000184744
keratin 222
chr1_+_58990121 0.51 ENSDART00000171654

chr19_+_14352332 0.51 ENSDART00000164386
AT rich interactive domain 1Ab (SWI-like)
chr17_-_10059557 0.50 ENSDART00000092209
ENSDART00000161243
bromodomain adjacent to zinc finger domain, 1A
chr13_-_51922290 0.50 ENSDART00000168648
serum response factor b
chr22_+_22438783 0.49 ENSDART00000147825
kinesin family member 14
chr8_+_45381298 0.49 ENSDART00000149451
ENSDART00000110364
TELO2 interacting protein 2
chr19_-_2231146 0.49 ENSDART00000181909
ENSDART00000043595
twist family bHLH transcription factor 1a
chr18_+_19772874 0.49 ENSDART00000043455
SMAD family member 3b
chr12_-_49168398 0.48 ENSDART00000186608

chr7_+_36898622 0.48 ENSDART00000190773
TOX high mobility group box family member 3
chr24_-_26518972 0.48 ENSDART00000097792
TRAF2 and NCK interacting kinase b
chr14_-_1949277 0.47 ENSDART00000159435
protocadherin 2 gamma 5
chr7_+_16835218 0.46 ENSDART00000173580
neuron navigator 2a
chr17_-_23412705 0.45 ENSDART00000126995
si:ch211-149k12.3
chr17_+_26783828 0.45 ENSDART00000154921
La ribonucleoprotein domain family, member 1B
chr7_+_39720317 0.44 ENSDART00000164996
si:dkey-58i8.5
chr17_+_28624321 0.44 ENSDART00000122260
HEAT repeat containing 5a
chr3_+_60957512 0.44 ENSDART00000044096
helicase with zinc finger
chr1_+_14454663 0.44 ENSDART00000005067
recombination signal binding protein for immunoglobulin kappa J region a
chr13_+_15941850 0.43 ENSDART00000016294
fidgetin-like 1
chr5_+_59234421 0.43 ENSDART00000045518
PRKR interacting protein 1
chr14_-_2004291 0.42 ENSDART00000114039
protocadherin 2 gamma 5
chr25_-_27729046 0.42 ENSDART00000131437
zgc:153935
chr22_-_10539180 0.42 ENSDART00000131217
inositol 1,3,4,5,6-pentakisphosphate 2-kinase
chr13_-_40316367 0.41 ENSDART00000009343
pyridine nucleotide-disulphide oxidoreductase domain 2
chr12_+_14149686 0.41 ENSDART00000123741
kelch repeat and BTB (POZ) domain containing 2
chr3_+_14157090 0.41 ENSDART00000156766
si:ch211-108d22.2
chr19_+_49721 0.41 ENSDART00000160489
collagen, type XIV, alpha 1b
chr17_-_25630822 0.40 ENSDART00000126201
ENSDART00000105503
ENSDART00000151878
RAB3 GTPase activating protein subunit 2 (non-catalytic)
chr20_-_1560724 0.40 ENSDART00000179193
ENSDART00000092508
ENSDART00000133369
protein tyrosine phosphatase, receptor type, K
chr24_-_24060460 0.39 ENSDART00000142813
ATP-binding cassette, sub-family C (CFTR/MRP), member 13
chr8_+_54137350 0.39 ENSDART00000164153
bromodomain and PHD finger containing, 1
chr6_+_58543336 0.39 ENSDART00000157018
stathmin-like 3
chr6_-_60104628 0.38 ENSDART00000057463
ENSDART00000169188
prostate transmembrane protein, androgen induced 1
chr3_-_15667713 0.38 ENSDART00000026658
zgc:66474
chr14_+_14806851 0.38 ENSDART00000169235
FH2 domain containing 2
chr23_-_6722101 0.37 ENSDART00000157828
bromodomain adjacent to zinc finger domain, 2A
chr21_-_13972745 0.37 ENSDART00000143874
AT-hook transcription factor
chr19_+_43256986 0.37 ENSDART00000182336
diacylglycerol kinase delta
chr17_-_22048233 0.37 ENSDART00000155203
tau tubulin kinase 1b
chr18_+_62932 0.36 ENSDART00000052638
solute carrier family 27 (fatty acid transporter), member 2a
chr4_+_14971239 0.36 ENSDART00000005985
smoothened, frizzled class receptor
chr24_+_24170914 0.35 ENSDART00000127842
si:dkey-226l10.6
chr19_-_2029777 0.34 ENSDART00000128639

chr6_-_10788065 0.34 ENSDART00000190968
WAS/WASL interacting protein family, member 1b
chr19_-_31765615 0.34 ENSDART00000103636
si:dkeyp-120h9.1
chr5_+_24087035 0.34 ENSDART00000183644
tumor protein p53
chr25_+_2993855 0.34 ENSDART00000163009
neogenin 1b
chr3_-_24205339 0.34 ENSDART00000157135
si:dkey-110g7.8
chr2_-_43123949 0.33 ENSDART00000075347
ENSDART00000132346
leucine rich repeat containing 6
chr6_+_269204 0.33 ENSDART00000191678
activating transcription factor 4a
chr19_+_14059349 0.33 ENSDART00000166230
trophoblast glycoprotein a
chr23_-_45504991 0.33 ENSDART00000148761
collagen type XXIV alpha 1
chr1_+_45056371 0.33 ENSDART00000073689
ENSDART00000167309
bloodthirsty-related gene family, member 1
chr15_-_434503 0.33 ENSDART00000122286

chr14_+_23518110 0.32 ENSDART00000112930
si:ch211-221f10.2
chr22_+_30009926 0.32 ENSDART00000142529
si:dkey-286j15.1
chr1_+_21725821 0.32 ENSDART00000132602
paired box 5
chr10_-_641609 0.32 ENSDART00000041236
regulatory factor X, 3 (influences HLA class II expression)
chr15_-_33807758 0.32 ENSDART00000158445
PDS5 cohesin associated factor B
chr1_-_39943596 0.31 ENSDART00000149730
storkhead box 2a
chr11_+_807153 0.31 ENSDART00000173289
vestigial-like family member 4b
chr7_+_51103232 0.31 ENSDART00000073827
collagen, type IV, alpha 5 (Alport syndrome)
chr22_+_17531214 0.31 ENSDART00000161174
ENSDART00000088356
heterogeneous nuclear ribonucleoprotein M
chr12_+_16452575 0.31 ENSDART00000058665
kinesin family member 20Bb
chr22_+_17531020 0.30 ENSDART00000137689
heterogeneous nuclear ribonucleoprotein M
chr14_+_18785727 0.30 ENSDART00000184452
si:ch211-111e20.1
chr7_+_13491452 0.30 ENSDART00000053535
ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 like
chr9_-_32668928 0.30 ENSDART00000135798
granzyme 3, tandem duplicate 3
chr10_-_35177257 0.30 ENSDART00000077426
POM121 transmembrane nucleoporin
chr2_-_44282796 0.30 ENSDART00000163040
ENSDART00000166923
ENSDART00000056372
ENSDART00000109251
ENSDART00000132682
myelin protein zero
chr11_-_44999858 0.30 ENSDART00000167759
ENSDART00000126845
LIM-domain binding 1b
chr25_+_36311333 0.30 ENSDART00000190174
histone cluster 1 H2A family member 2
chr17_+_38573471 0.30 ENSDART00000040627
spectrin, beta, erythrocytic
chr11_+_12811906 0.30 ENSDART00000123445
regulator of telomere elongation helicase 1
chr23_+_2717950 0.29 ENSDART00000137641
nuclear receptor coactivator 6
chr6_+_59991076 0.29 ENSDART00000163575

chr23_+_43770149 0.29 ENSDART00000024313
ring finger protein 150b
chr1_+_55080797 0.28 ENSDART00000077390
lectin, galactoside-binding-like a
chr1_-_45584407 0.28 ENSDART00000149155
activating transcription factor 7 interacting protein
chr8_+_36554816 0.28 ENSDART00000126687
splicing factor 3a, subunit 1
chr3_-_27065477 0.27 ENSDART00000185660
activating transcription factor 7 interacting protein 2
chr7_-_56831621 0.27 ENSDART00000182912
SUMO/sentrin peptidase family member, NEDD8 specific
chr20_+_305035 0.27 ENSDART00000104807
si:dkey-119m7.4
chr2_+_1989941 0.26 ENSDART00000190814
synovial sarcoma, X breakpoint 2 interacting protein a
chr22_-_876506 0.26 ENSDART00000137522
choline/ethanolamine phosphotransferase 1b
chr5_-_32445835 0.26 ENSDART00000170919
neuronal calcium sensor 1a
chr11_+_31324335 0.26 ENSDART00000088093
signal-induced proliferation-associated 1 like 2
chr5_-_2672492 0.26 ENSDART00000192337

chr19_-_15855427 0.26 ENSDART00000133059
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4a
chr12_+_16452912 0.25 ENSDART00000192467
kinesin family member 20Bb
chr2_+_50094873 0.25 ENSDART00000132307
zinc finger, CCHC domain containing 2
chr22_-_968484 0.25 ENSDART00000105895
calcium channel, voltage-dependent, L type, alpha 1S subunit, a
chr15_-_25198107 0.25 ENSDART00000159793
MAX network transcriptional repressor a
chr7_-_29223614 0.25 ENSDART00000173598
HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
chr2_+_45374163 0.24 ENSDART00000193650
calmodulin regulated spectrin-associated protein family, member 2b
chr12_+_18744610 0.24 ENSDART00000153456
megakaryoblastic leukemia (translocation) 1b
chr1_+_6243906 0.24 ENSDART00000127329
general transcription factor IIIC, polypeptide 3
chr14_+_39156 0.24 ENSDART00000082184
transmembrane protein 107
chr2_+_49572059 0.24 ENSDART00000108861
semaphorin 4e
chr7_-_25697285 0.24 ENSDART00000082620
dysferlin, limb girdle muscular dystrophy 2B (autosomal recessive)
chr13_-_10431476 0.24 ENSDART00000133968
calmodulin-lysine N-methyltransferase
chr1_-_44928987 0.24 ENSDART00000134635
si:dkey-9i23.15
chr20_+_54333774 0.23 ENSDART00000144633
CLOCK-interacting pacemaker b
chr9_+_21535885 0.23 ENSDART00000141408
Rho guanine nucleotide exchange factor (GEF) 7a
chr9_-_30371247 0.23 ENSDART00000079068
ankyrin repeat and SOCS box containing 11
chr2_-_7185460 0.23 ENSDART00000092078
ring finger and CCCH-type domains 1b
chr10_-_7666810 0.23 ENSDART00000191479
prenylcysteine oxidase 1
chr8_-_18613948 0.23 ENSDART00000089172
coproporphyrinogen oxidase
chr8_+_26868105 0.23 ENSDART00000005337
ribosomal modification protein rimK-like family member A
chr12_+_13348918 0.23 ENSDART00000181373
ribonuclease type III, nuclear
chr4_+_63928858 0.23 ENSDART00000161958
si:dkey-179k24.2
chr21_-_15200556 0.23 ENSDART00000141809
splicing factor SWAP
chr24_-_26715174 0.23 ENSDART00000079726
phospholipase D1b
chr14_-_36325558 0.23 ENSDART00000172783
epidermal growth factor
chr5_-_32505276 0.22 ENSDART00000034705
ENSDART00000187597
N-terminal Xaa-Pro-Lys N-methyltransferase 1
chr24_+_28525507 0.22 ENSDART00000191121
Rho GTPase activating protein 29a
chr20_-_46694573 0.22 ENSDART00000182557

chr3_+_16229911 0.22 ENSDART00000121728
ribosomal protein L19
chr5_+_21225017 0.22 ENSDART00000141573
si:dkey-13n15.11
chr13_-_4367083 0.22 ENSDART00000124716
si:dkeyp-121d4.3
chr1_-_40102836 0.22 ENSDART00000147317
ciliary neurotrophic factor
chr11_+_13424116 0.21 ENSDART00000125563
homer scaffolding protein 3b
chr21_+_39941559 0.21 ENSDART00000189718
ENSDART00000160875
ENSDART00000135235
solute carrier family 47 (multidrug and toxin extrusion), member 1
chr13_+_31070181 0.21 ENSDART00000110560
ENSDART00000146088
si:ch211-223a10.1
chr14_-_23801389 0.21 ENSDART00000054264
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr14_-_237130 0.21 ENSDART00000164988
biorientation of chromosomes in cell division 1-like 1
chr18_-_17074155 0.21 ENSDART00000143304
transport and golgi organization 6 homolog (Drosophila)
chr7_-_41554047 0.21 ENSDART00000174144
plexin domain containing 2
chr6_-_43387920 0.21 ENSDART00000154434
FERM domain containing 4Ba
chr19_-_3298352 0.21 ENSDART00000147182
si:ch211-133n4.7
chr1_+_16600690 0.20 ENSDART00000162164
microtubule associated tumor suppressor 1b
chr6_-_31233696 0.20 ENSDART00000079173
leptin receptor
chr19_+_4892281 0.20 ENSDART00000150969
cyclin-dependent kinase 12
chr19_+_6938289 0.20 ENSDART00000139122
ENSDART00000178832
flotillin 1b
chr2_+_4383061 0.20 ENSDART00000163986
WW domain containing adaptor with coiled-coil b
chr21_+_25643880 0.19 ENSDART00000192392
ENSDART00000145091
transmembrane protein 151A
chr5_+_53482597 0.19 ENSDART00000180333

chr13_-_280652 0.19 ENSDART00000193627
solute carrier family 30 (zinc transporter), member 6
chr9_-_27717006 0.19 ENSDART00000146860
general transcription factor IIE, polypeptide 1, alpha
chr9_-_54344405 0.19 ENSDART00000182939

chr11_-_25734417 0.19 ENSDART00000103570
bromodomain and PHD finger containing, 3a
chr6_-_52156427 0.19 ENSDART00000082821
regulating synaptic membrane exocytosis 4
chr5_-_32505109 0.19 ENSDART00000188219
N-terminal Xaa-Pro-Lys N-methyltransferase 1
chr12_-_33893381 0.19 ENSDART00000153280
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4Gb
chr1_-_19502322 0.19 ENSDART00000181888
ENSDART00000044030
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog b
chr23_+_2825940 0.18 ENSDART00000135781
phospholipase C, gamma 1
chr18_-_17087138 0.18 ENSDART00000135597
zinc finger CCCH-type containing 18
chr11_-_42315748 0.18 ENSDART00000169853
sarcolemma associated protein a
chr12_-_37449396 0.18 ENSDART00000152951
CDC42 effector protein (Rho GTPase binding) 4b
chr17_+_49081828 0.18 ENSDART00000156492
T cell lymphoma invasion and metastasis 2a
chr25_+_336503 0.18 ENSDART00000160395

chr19_-_82504 0.17 ENSDART00000027864
ENSDART00000160560
heterogeneous nuclear ribonucleoprotein R
chr12_+_44610912 0.17 ENSDART00000179030
ENSDART00000178008
family with sequence similarity 196 member A
chr6_-_48347724 0.17 ENSDART00000046973
capping protein (actin filament) muscle Z-line, alpha 1a
chr11_+_45343245 0.17 ENSDART00000160904
si:ch73-100l22.3
chr10_-_40826657 0.17 ENSDART00000076304
proliferating cell nuclear antigen
chr10_+_34377697 0.17 ENSDART00000189441
StAR-related lipid transfer (START) domain containing 13a
chr15_+_1397811 0.17 ENSDART00000102125
schwannomin interacting protein 1
chr2_-_2642476 0.17 ENSDART00000124032
SERPINE1 mRNA binding protein 1b
chr24_-_25166416 0.17 ENSDART00000111552
ENSDART00000169495
pleckstrin homology-like domain, family B, member 2b
chr10_-_42237304 0.17 ENSDART00000140341
transcription factor 7 like 1a
chr8_+_13106760 0.17 ENSDART00000029308
integrin, beta 4
chr21_-_11646878 0.17 ENSDART00000162426
ENSDART00000135937
ENSDART00000131448
ENSDART00000148097
ENSDART00000133443
calpastatin
chr14_+_16287968 0.16 ENSDART00000106593
pre-mRNA processing factor 19
chr22_-_26524596 0.16 ENSDART00000087623
zgc:194330
chr18_-_44356656 0.16 ENSDART00000193084
PR domain containing 10
chr4_+_33537372 0.16 ENSDART00000181450
si:dkey-84h14.2
chr3_+_28502419 0.16 ENSDART00000151081
septin 12
chr24_+_18689980 0.16 ENSDART00000160941
ENSDART00000180303
ENSDART00000190435
centrosome and spindle pole associated protein 1a
chr24_-_14711597 0.16 ENSDART00000131830
junctophilin 1a

Network of associatons between targets according to the STRING database.

First level regulatory network of rcor1+rcor2+rcor3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0061032 visceral serous pericardium development(GO:0061032)
0.2 0.8 GO:0007412 axon target recognition(GO:0007412)
0.2 0.6 GO:0010610 regulation of mRNA stability involved in response to stress(GO:0010610) regulation of mRNA stability involved in response to oxidative stress(GO:2000815)
0.1 0.4 GO:0072314 glomerular visceral epithelial cell fate commitment(GO:0072149) glomerular epithelial cell fate commitment(GO:0072314)
0.1 0.6 GO:1901881 positive regulation of protein depolymerization(GO:1901881)
0.1 0.4 GO:0006480 N-terminal protein amino acid methylation(GO:0006480)
0.1 0.8 GO:0055016 hypochord development(GO:0055016)
0.1 0.5 GO:2000622 negative regulation of mRNA catabolic process(GO:1902373) regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.1 0.5 GO:0060829 negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
0.1 0.4 GO:0060844 arterial endothelial cell fate commitment(GO:0060844)
0.1 0.3 GO:1901216 regulation of transposition, RNA-mediated(GO:0010525) negative regulation of transposition, RNA-mediated(GO:0010526) transposition, RNA-mediated(GO:0032197) positive regulation of neuron apoptotic process(GO:0043525) positive regulation of neuron death(GO:1901216)
0.1 0.4 GO:0052746 inositol phosphorylation(GO:0052746)
0.1 0.2 GO:0035477 regulation of angioblast cell migration involved in selective angioblast sprouting(GO:0035477)
0.1 0.5 GO:2001106 regulation of guanyl-nucleotide exchange factor activity(GO:1905097) regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 0.7 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.1 0.3 GO:0006521 regulation of cellular amino acid metabolic process(GO:0006521) regulation of cellular amine metabolic process(GO:0033238)
0.1 0.2 GO:1901890 positive regulation of cell junction assembly(GO:1901890)
0.1 0.2 GO:0001112 DNA-templated transcriptional open complex formation(GO:0001112) transcriptional open complex formation at RNA polymerase II promoter(GO:0001113) protein-DNA complex remodeling(GO:0001120)
0.1 0.2 GO:0042117 plasma membrane repair(GO:0001778) monocyte activation(GO:0042117)
0.1 0.2 GO:0032530 regulation of microvillus organization(GO:0032530) regulation of microvillus assembly(GO:0032534)
0.1 0.3 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.1 0.4 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1 0.2 GO:0071387 cellular response to cortisol stimulus(GO:0071387) response to dexamethasone(GO:0071548)
0.1 0.5 GO:0032205 negative regulation of telomere maintenance(GO:0032205)
0.0 0.1 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.0 0.2 GO:0010693 regulation of alkaline phosphatase activity(GO:0010692) negative regulation of alkaline phosphatase activity(GO:0010693)
0.0 0.2 GO:0010332 response to gamma radiation(GO:0010332) cellular response to gamma radiation(GO:0071480)
0.0 0.5 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.0 0.2 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.2 GO:0030329 prenylated protein catabolic process(GO:0030327) prenylcysteine catabolic process(GO:0030328) prenylcysteine metabolic process(GO:0030329)
0.0 0.2 GO:0038093 Fc receptor signaling pathway(GO:0038093)
0.0 0.2 GO:1903723 negative regulation of centriole elongation(GO:1903723)
0.0 0.2 GO:0006272 leading strand elongation(GO:0006272)
0.0 0.6 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.0 0.2 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.0 0.1 GO:0097384 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) cellular lipid biosynthetic process(GO:0097384) ether biosynthetic process(GO:1901503)
0.0 0.2 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.3 GO:0060118 reflex(GO:0060004) vestibular reflex(GO:0060005) vestibular receptor cell differentiation(GO:0060114) vestibular receptor cell development(GO:0060118)
0.0 0.1 GO:1904983 transmembrane glycine transport from cytosol to mitochondrion(GO:1904983)
0.0 0.1 GO:0072156 distal tubule morphogenesis(GO:0072156)
0.0 0.2 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.2 GO:0035332 positive regulation of hippo signaling(GO:0035332)
0.0 0.1 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.3 GO:0070309 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0070059) lens fiber cell development(GO:0070307) lens fiber cell morphogenesis(GO:0070309)
0.0 0.1 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.0 0.2 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0 0.2 GO:0097340 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.0 0.1 GO:0071034 cerebellar Purkinje cell layer structural organization(GO:0021693) cerebellar cortex structural organization(GO:0021698) CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0 0.5 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.3 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.3 GO:0032264 IMP salvage(GO:0032264)
0.0 0.3 GO:0031937 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.1 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
0.0 0.2 GO:0031111 negative regulation of microtubule depolymerization(GO:0007026) negative regulation of microtubule polymerization or depolymerization(GO:0031111)
0.0 0.1 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
0.0 0.5 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0 0.1 GO:0070973 positive regulation of protein exit from endoplasmic reticulum(GO:0070863) protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.2 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.0 0.1 GO:0010801 regulation of peptidyl-threonine phosphorylation(GO:0010799) negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.0 0.2 GO:0031272 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.6 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 0.4 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.8 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 0.5 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.0 0.1 GO:0006212 uracil catabolic process(GO:0006212) beta-alanine metabolic process(GO:0019482) beta-alanine biosynthetic process(GO:0019483) uracil metabolic process(GO:0019860) 'de novo' UMP biosynthetic process(GO:0044205)
0.0 0.1 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024) CDP-diacylglycerol metabolic process(GO:0046341)
0.0 0.2 GO:0046501 protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.3 GO:0035329 hippo signaling(GO:0035329)
0.0 0.1 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 0.7 GO:0043491 protein kinase B signaling(GO:0043491)
0.0 0.3 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.0 0.5 GO:0060037 pharyngeal system development(GO:0060037)
0.0 0.3 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.3 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.2 GO:0070328 acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
0.0 1.0 GO:0031047 gene silencing by RNA(GO:0031047)
0.0 0.1 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0031213 RSF complex(GO:0031213)
0.1 0.5 GO:0070209 ASTRA complex(GO:0070209)
0.1 0.3 GO:0005592 collagen type XI trimer(GO:0005592)
0.1 0.6 GO:0031332 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.1 0.5 GO:0035060 brahma complex(GO:0035060)
0.1 0.3 GO:0008091 spectrin(GO:0008091)
0.1 0.3 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.2 GO:0016600 flotillin complex(GO:0016600)
0.0 0.6 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.0 0.2 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.2 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.0 0.7 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.2 GO:0000974 Prp19 complex(GO:0000974)
0.0 0.2 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.6 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.3 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.5 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.2 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.2 GO:0019908 cyclin/CDK positive transcription elongation factor complex(GO:0008024) nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.0 0.6 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.3 GO:0043209 myelin sheath(GO:0043209)
0.0 0.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.2 GO:0030315 T-tubule(GO:0030315)
0.0 0.2 GO:0035101 FACT complex(GO:0035101)
0.0 0.4 GO:0043186 P granule(GO:0043186)
0.0 0.3 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.8 GO:0030173 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 0.2 GO:0070187 telosome(GO:0070187)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1 0.4 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.1 0.6 GO:0019215 intermediate filament binding(GO:0019215)
0.1 0.2 GO:0072590 N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590) citrate-L-glutamate ligase activity(GO:0072591)
0.1 0.4 GO:0070412 R-SMAD binding(GO:0070412)
0.1 0.3 GO:0070182 DNA polymerase binding(GO:0070182)
0.1 0.5 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1 0.7 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.1 0.3 GO:0001223 transcription coactivator binding(GO:0001223)
0.1 0.4 GO:0008142 oxysterol binding(GO:0008142)
0.1 0.7 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.3 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.0 0.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.2 GO:0001735 prenylcysteine oxidase activity(GO:0001735)
0.0 0.2 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.3 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.6 GO:0043994 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.0 0.4 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.2 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.2 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.3 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.2 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0 0.5 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.4 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.2 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.1 GO:0001047 core promoter sequence-specific DNA binding(GO:0001046) core promoter binding(GO:0001047)
0.0 0.2 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.2 GO:0030332 cyclin binding(GO:0030332)
0.0 0.1 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0 0.2 GO:0030507 spectrin binding(GO:0030507)
0.0 0.1 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.0 0.1 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.4 GO:0004860 protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210)
0.0 1.0 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 0.1 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.3 GO:0042910 xenobiotic transporter activity(GO:0042910)
0.0 0.2 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.5 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.1 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.3 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.3 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.2 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.1 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.7 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.5 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.2 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.1 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.2 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.3 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.2 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.4 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.2 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 1.0 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.2 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.2 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.8 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.3 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.5 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 1.2 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.4 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.3 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.1 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.2 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.3 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.4 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.2 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.2 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 0.1 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.2 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.0 0.2 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.3 REACTOME RNA POL II PRE TRANSCRIPTION EVENTS Genes involved in RNA Polymerase II Pre-transcription Events
0.0 0.2 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter