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PRJEB1986: zebrafish developmental stages transcriptome

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Results for pou4f2

Z-value: 1.10

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Transcription factors associated with pou4f2

Gene Symbol Gene ID Gene Info
pou4f2
ENSDARG00000069737 POU class 4 homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
pou4f2dr11_v1_chr1_+_36437585_364375850.724.8e-04Click!

Activity profile of pou4f2 motif

Sorted Z-values of pou4f2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_31079186 4.15 ENSDART00000145636
ENSDART00000140569
ELOB (1 of many)
elob
elongin B
elongin B
chr21_+_25226558 4.11 ENSDART00000168480
sycn.2
syncollin, tandem duplicate 2
chr17_-_37395460 3.75 ENSDART00000148160
ENSDART00000075975
crip1
cysteine-rich protein 1
chr8_-_40555340 3.62 ENSDART00000163348
NPC1L1
NPC1 like intracellular cholesterol transporter 1
chr10_-_17159761 3.45 ENSDART00000080449
slc5a1
solute carrier family 5 (sodium/glucose cotransporter), member 1
chr8_-_4327473 3.22 ENSDART00000134378
cux2b
cut-like homeobox 2b
chr4_-_1360495 3.02 ENSDART00000164623
ptn
pleiotrophin
chr12_-_35787801 2.87 ENSDART00000171682
aatkb
apoptosis-associated tyrosine kinase b
chr1_-_22512063 2.84 ENSDART00000031546
ENSDART00000190987
chrna6
cholinergic receptor, nicotinic, alpha 6
chr5_-_38155005 2.69 ENSDART00000097770
gucy2d
guanylate cyclase 2D, retinal
chr9_-_23944470 2.51 ENSDART00000138754
col6a3
collagen, type VI, alpha 3
chr5_+_26248380 2.51 ENSDART00000079049
si:ch211-214j8.1
si:ch211-214j8.1
chr17_+_51499789 2.47 ENSDART00000187701
CABZ01067581.1

chr16_-_12173554 2.46 ENSDART00000110567
ENSDART00000155935
clstn3
calsyntenin 3
chr7_+_49862837 2.37 ENSDART00000174315
slc1a2a
solute carrier family 1 (glial high affinity glutamate transporter), member 2a
chr5_+_51443009 2.31 ENSDART00000083350
rasgrf2b
Ras protein-specific guanine nucleotide-releasing factor 2b
chr16_-_12173399 2.22 ENSDART00000142574
clstn3
calsyntenin 3
chr1_-_50859053 2.11 ENSDART00000132779
ENSDART00000137648
si:dkeyp-123h10.2
si:dkeyp-123h10.2
chr6_+_27146671 2.10 ENSDART00000156792
kif1aa
kinesin family member 1Aa
chr3_-_32169754 2.08 ENSDART00000179010
tnnt1
troponin T type 1 (skeletal, slow)
chr16_-_26074529 2.04 ENSDART00000148653
ENSDART00000148923
tmem145
transmembrane protein 145
chr13_+_1089942 1.98 ENSDART00000054322
cnrip1b
cannabinoid receptor interacting protein 1b
chr8_+_44714336 1.73 ENSDART00000145801
elmod3
ELMO/CED-12 domain containing 3
chr19_-_31402429 1.71 ENSDART00000137292
tmem106bb
transmembrane protein 106Bb
chr7_+_73630751 1.65 ENSDART00000159745
PCP4L1
si:dkey-46i9.1
chr11_+_38280454 1.65 ENSDART00000171496
CDK18
si:dkey-166c18.1
chr11_+_14937904 1.63 ENSDART00000185103
CR550302.3

chr2_-_30734098 1.61 ENSDART00000133769
rp1
retinitis pigmentosa 1 (autosomal dominant)
chr10_-_35103208 1.54 ENSDART00000192734
zgc:110006
zgc:110006
chr3_-_30434016 1.54 ENSDART00000150958
lrrc4ba
leucine rich repeat containing 4Ba
chr13_+_31180084 1.52 ENSDART00000133774
ptpn20
protein tyrosine phosphatase, non-receptor type 20
chr11_+_3585934 1.51 ENSDART00000055694
cdab
cytidine deaminase b
chr18_-_2433011 1.50 ENSDART00000181922
ENSDART00000193276
CR769778.1

chr23_-_28141419 1.48 ENSDART00000133039
tac3a
tachykinin 3a
chr22_+_10698549 1.46 ENSDART00000081228
abhd14a
abhydrolase domain containing 14A
chr8_+_16025554 1.46 ENSDART00000110171
elavl4
ELAV like neuron-specific RNA binding protein 4
chr21_+_28958471 1.45 ENSDART00000144331
ENSDART00000005929
ppp3ca
protein phosphatase 3, catalytic subunit, alpha isozyme
chr17_+_8183393 1.45 ENSDART00000155957
tulp4b
tubby like protein 4b
chr14_-_7306983 1.43 ENSDART00000158914
si:ch211-51f19.1
si:ch211-51f19.1
chr16_-_40043322 1.39 ENSDART00000145278
si:dkey-29b11.3
si:dkey-29b11.3
chr19_-_5103313 1.37 ENSDART00000037007
tpi1a
triosephosphate isomerase 1a
chr11_-_37509001 1.35 ENSDART00000109753
bsnb
bassoon (presynaptic cytomatrix protein) b
chr9_-_19699728 1.27 ENSDART00000166780
si:ch211-141e20.2
si:ch211-141e20.2
chr7_+_25059845 1.25 ENSDART00000077215
ppp2r5b
protein phosphatase 2, regulatory subunit B', beta
chr13_+_31177934 1.19 ENSDART00000144568
ptpn20
protein tyrosine phosphatase, non-receptor type 20
chr5_+_44064764 1.16 ENSDART00000143843
si:dkey-84j12.1
si:dkey-84j12.1
chr14_-_31465905 1.16 ENSDART00000173108
gpc3
glypican 3
chr10_+_38775408 1.15 ENSDART00000125045
dscama
Down syndrome cell adhesion molecule a
chr16_-_22294265 1.15 ENSDART00000124718
aqp10a
aquaporin 10a
chr15_+_45994123 1.14 ENSDART00000124704
lrfn1
leucine rich repeat and fibronectin type III domain containing 1
chr23_-_15284757 1.13 ENSDART00000139135
sulf2b
sulfatase 2b
chr25_+_6186823 1.09 ENSDART00000153526
oaz2a
ornithine decarboxylase antizyme 2a
chr17_-_29194219 1.09 ENSDART00000157340
sptbn5
spectrin, beta, non-erythrocytic 5
chr18_+_783936 1.08 ENSDART00000193357
rpp25b
ribonuclease P and MRP subunit p25, b
chr11_-_44498975 1.06 ENSDART00000173066
ENSDART00000189976
si:ch1073-365p7.2
si:ch1073-365p7.2
chr10_+_38526496 1.06 ENSDART00000144329
acer3
alkaline ceramidase 3
chr12_+_32729470 1.05 ENSDART00000175712
rbfox3a
RNA binding fox-1 homolog 3a
chr17_+_15433518 1.05 ENSDART00000026180
fabp7a
fatty acid binding protein 7, brain, a
chr20_-_38617766 1.04 ENSDART00000050474
slc30a2
solute carrier family 30 (zinc transporter), member 2
chr8_+_6576940 1.02 ENSDART00000138135
vsig8b
V-set and immunoglobulin domain containing 8b
chr14_+_25817628 1.02 ENSDART00000047680
glra1
glycine receptor, alpha 1
chr17_-_12926456 0.98 ENSDART00000044126
INSM2
INSM transcriptional repressor 2
chr21_-_20733615 0.97 ENSDART00000145544
si:ch211-22d5.2
si:ch211-22d5.2
chr15_-_16121496 0.97 ENSDART00000128624
sgk494a
uncharacterized serine/threonine-protein kinase SgK494a
chr3_-_23406964 0.96 ENSDART00000114723
rapgefl1
Rap guanine nucleotide exchange factor (GEF)-like 1
chr16_+_30301539 0.96 ENSDART00000186018
LO017848.1

chr11_-_42918971 0.95 ENSDART00000052912
pcdh20
protocadherin 20
chr3_-_33574576 0.94 ENSDART00000184881
CR847537.1

chr18_-_1185772 0.93 ENSDART00000143245
nptnb
neuroplastin b
chr13_+_36622100 0.91 ENSDART00000133198
si:ch211-67f24.7
si:ch211-67f24.7
chr3_-_30384353 0.89 ENSDART00000186832
lrrc4ba
leucine rich repeat containing 4Ba
chr14_+_45883687 0.88 ENSDART00000114790
flrt1b
fibronectin leucine rich transmembrane protein 1b
chr17_+_11675362 0.88 ENSDART00000157911
kif26ba
kinesin family member 26Ba
chr1_-_53756851 0.85 ENSDART00000122445
akt3b
v-akt murine thymoma viral oncogene homolog 3b
chr17_+_15433671 0.83 ENSDART00000149568
fabp7a
fatty acid binding protein 7, brain, a
chr19_-_5103141 0.82 ENSDART00000150952
tpi1a
triosephosphate isomerase 1a
chr8_+_52314542 0.82 ENSDART00000013059
ENSDART00000125241
dbnlb
drebrin-like b
chr9_-_50001606 0.80 ENSDART00000161648
ENSDART00000168514
scn1a
sodium channel, voltage-gated, type I, alpha
chr25_-_13842618 0.80 ENSDART00000160258
mapk8ip1a
mitogen-activated protein kinase 8 interacting protein 1a
chr10_+_38775959 0.79 ENSDART00000192990
dscama
Down syndrome cell adhesion molecule a
chr3_+_56276346 0.78 ENSDART00000157770
PRKCA
si:ch73-374l24.1
chr22_-_13042992 0.77 ENSDART00000028787
ahr1b
aryl hydrocarbon receptor 1b
chr21_-_7035599 0.76 ENSDART00000139777
si:ch211-93g21.1
si:ch211-93g21.1
chr3_+_45687266 0.75 ENSDART00000131652
gpr146
G protein-coupled receptor 146
chr19_+_42470396 0.75 ENSDART00000191679
si:dkey-166k12.1
si:dkey-166k12.1
chr21_+_36623162 0.69 ENSDART00000027459
grk6
G protein-coupled receptor kinase 6
chr2_+_50608099 0.65 ENSDART00000185805
ENSDART00000111135
neurod6b
neuronal differentiation 6b
chr20_-_18736281 0.65 ENSDART00000142837
enpp5
ectonucleotide pyrophosphatase/phosphodiesterase 5
chr2_-_30784198 0.64 ENSDART00000182523
ENSDART00000147355
rgs20
regulator of G protein signaling 20
chr7_-_18416741 0.64 ENSDART00000097882
sstr1b
somatostatin receptor 1b
chr11_-_2478374 0.64 ENSDART00000173205
si:ch73-267c23.10
si:ch73-267c23.10
chr16_+_29303971 0.63 ENSDART00000087149
hapln2
hyaluronan and proteoglycan link protein 2
chr9_-_29003245 0.63 ENSDART00000183391
ENSDART00000188836
ptpn4a
protein tyrosine phosphatase, non-receptor type 4a
chr13_-_37109987 0.61 ENSDART00000136750
syne2b
spectrin repeat containing, nuclear envelope 2b
chr6_+_39184236 0.61 ENSDART00000156187
tac3b
tachykinin 3b
chr3_-_58798815 0.58 ENSDART00000082920
si:ch73-281f12.4
si:ch73-281f12.4
chr1_+_25801648 0.58 ENSDART00000129471
gucy1b1
guanylate cyclase 1 soluble subunit beta 1
chr10_+_2582254 0.52 ENSDART00000016103
nxnl2
nucleoredoxin like 2
chr13_-_14487524 0.51 ENSDART00000141103
gfra4a
GDNF family receptor alpha 4a
chr9_+_38088331 0.51 ENSDART00000123749
cacnb4a
calcium channel, voltage-dependent, beta 4a subunit
chr13_-_42400647 0.48 ENSDART00000043069
march5
membrane-associated ring finger (C3HC4) 5
chr9_-_32158288 0.48 ENSDART00000037182
ankrd44
ankyrin repeat domain 44
chr7_-_69185124 0.45 ENSDART00000182217
ENSDART00000191359
usp10
ubiquitin specific peptidase 10
chr10_+_40284003 0.44 ENSDART00000062795
ENSDART00000193825
ENSDART00000113582
git2b
G protein-coupled receptor kinase interacting ArfGAP 2b
chr10_+_2899108 0.43 ENSDART00000147031
erap1a
endoplasmic reticulum aminopeptidase 1a
chr1_-_17715493 0.42 ENSDART00000133027
si:dkey-256e7.8
si:dkey-256e7.8
chr18_+_2228737 0.42 ENSDART00000165301
rab27a
RAB27A, member RAS oncogene family
chr8_+_17069577 0.41 ENSDART00000131847
si:dkey-190g11.3
si:dkey-190g11.3
chr5_+_42381273 0.41 ENSDART00000142387
pimr58
Pim proto-oncogene, serine/threonine kinase, related 58
chr2_+_23006792 0.41 ENSDART00000027782
mknk2a
MAP kinase interacting serine/threonine kinase 2a
chr21_-_25612658 0.39 ENSDART00000115276
fibpb
fibroblast growth factor (acidic) intracellular binding protein b
chr5_-_26247973 0.39 ENSDART00000098527
erap1b
endoplasmic reticulum aminopeptidase 1b
chr21_-_38853737 0.37 ENSDART00000184100
tlr22
toll-like receptor 22
chr9_-_43538328 0.36 ENSDART00000140526
znf385b
zinc finger protein 385B
chr20_-_31743553 0.36 ENSDART00000087405
sash1a
SAM and SH3 domain containing 1a
chr14_+_46287296 0.35 ENSDART00000183620
cabp2b
calcium binding protein 2b
chr3_-_1970820 0.29 ENSDART00000136467
si:ch211-254c8.3
si:ch211-254c8.3
chr3_+_33341640 0.28 ENSDART00000186352
pyya
peptide YYa
chr11_-_31226578 0.26 ENSDART00000109698
nacc1b
nucleus accumbens associated 1, BEN and BTB (POZ) domain containing b
chr4_-_23908802 0.26 ENSDART00000138873
celf2
cugbp, Elav-like family member 2
chr19_+_1688727 0.25 ENSDART00000115136
ENSDART00000166744
dennd3a
DENN/MADD domain containing 3a
chr5_+_17624463 0.25 ENSDART00000183869
ENSDART00000081064
fbrsl1
fibrosin-like 1
chr18_+_34362608 0.23 ENSDART00000131478
kcnab1a
potassium voltage-gated channel, shaker-related subfamily, beta member 1 a
chr8_-_17167819 0.21 ENSDART00000135042
ENSDART00000143920
mrps36
mitochondrial ribosomal protein S36
chr17_-_29902187 0.20 ENSDART00000009104
esrrb
estrogen-related receptor beta
chr13_-_16066997 0.19 ENSDART00000184790
SPATA48
spermatogenesis associated 48
chr14_+_29941445 0.19 ENSDART00000181761
fam149a
family with sequence similarity 149 member A
chr11_+_1575435 0.18 ENSDART00000155713
ENSDART00000156562
si:dkey-40c23.1
si:dkey-40c23.1
chr2_+_29249561 0.18 ENSDART00000099157
cdh18a
cadherin 18, type 2a
chr24_+_24808955 0.17 ENSDART00000080963
dnajc5b
DnaJ (Hsp40) homolog, subfamily C, member 5 beta
chr6_-_40466861 0.15 ENSDART00000062724
crbn
cereblon
chr20_+_41756996 0.15 ENSDART00000186393
fam184a
family with sequence similarity 184, member A
chr17_-_6765877 0.14 ENSDART00000193102
CR352340.1

chr24_-_40700596 0.13 ENSDART00000162635
smyhc2
slow myosin heavy chain 2
chr4_+_9836465 0.13 ENSDART00000004879
hsp90b1
heat shock protein 90, beta (grp94), member 1
chr4_-_2637689 0.10 ENSDART00000192550
ENSDART00000021953
ENSDART00000150344
cog5
component of oligomeric golgi complex 5
chr23_+_1276006 0.09 ENSDART00000162294
utrn
utrophin
chr20_+_18325556 0.09 ENSDART00000123559
znf521
zinc finger protein 521
chr5_-_72415578 0.09 ENSDART00000029014
pax8
paired box 8
chr11_-_45138857 0.08 ENSDART00000166501
cant1b
calcium activated nucleotidase 1b
chr18_-_48550426 0.07 ENSDART00000145189
kcnj1a.1
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 1
chr15_+_5280858 0.06 ENSDART00000174242
or121-1
odorant receptor, family E, subfamily 121, member 1
chr2_-_9818640 0.04 ENSDART00000139499
ENSDART00000165548
ENSDART00000012442
ENSDART00000046587
ap2m1b
adaptor-related protein complex 2, mu 1 subunit, b
chr5_+_37966505 0.04 ENSDART00000127648
pafah1b2
platelet-activating factor acetylhydrolase 1b, catalytic subunit 2
chr13_+_35339182 0.03 ENSDART00000019323
jag1b
jagged 1b
chr2_+_29249204 0.01 ENSDART00000168957
cdh18a
cadherin 18, type 2a
chr11_+_44502410 0.01 ENSDART00000172998
ero1b
endoplasmic reticulum oxidoreductase beta
chr7_-_33960170 0.00 ENSDART00000180766
skor1a
SKI family transcriptional corepressor 1a
chr7_-_7764287 0.00 ENSDART00000173021
ENSDART00000113131
intu
inturned planar cell polarity protein

Network of associatons between targets according to the STRING database.

First level regulatory network of pou4f2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.8 GO:0071236 cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237)
0.5 2.2 GO:0019242 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.5 2.1 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.5 4.7 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.5 1.5 GO:0006216 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.5 2.9 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.3 1.0 GO:0071361 cellular response to ethanol(GO:0071361)
0.3 2.2 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.2 2.0 GO:2000272 negative regulation of receptor activity(GO:2000272)
0.2 1.0 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.2 0.8 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.1 1.2 GO:0060976 coronary vasculature development(GO:0060976)
0.1 0.6 GO:0099543 trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by nitric oxide(GO:0099548)
0.1 1.5 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.1 1.4 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.1 1.1 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.1 2.7 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1 1.7 GO:0032418 lysosome localization(GO:0032418)
0.1 2.9 GO:0070593 dendrite self-avoidance(GO:0070593)
0.1 1.5 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.1 1.1 GO:0046520 sphingoid biosynthetic process(GO:0046520)
0.1 1.1 GO:0035860 esophagus smooth muscle contraction(GO:0014846) glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.1 4.1 GO:0006368 transcription elongation from RNA polymerase II promoter(GO:0006368)
0.1 0.8 GO:0019885 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.1 1.3 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.1 2.7 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.1 0.2 GO:1902260 negative regulation of potassium ion transmembrane transporter activity(GO:1901017) negative regulation of potassium ion transmembrane transport(GO:1901380) negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.0 3.0 GO:0051781 positive regulation of cell division(GO:0051781)
0.0 1.1 GO:0007020 microtubule nucleation(GO:0007020)
0.0 1.1 GO:0006595 polyamine metabolic process(GO:0006595)
0.0 0.6 GO:0071385 cellular response to corticosteroid stimulus(GO:0071384) cellular response to glucocorticoid stimulus(GO:0071385)
0.0 1.3 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 1.4 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.6 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.0 2.5 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 1.0 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 1.6 GO:0035082 axoneme assembly(GO:0035082)
0.0 0.1 GO:0035889 otolith tethering(GO:0035889)
0.0 0.4 GO:0018023 peptidyl-lysine trimethylation(GO:0018023)
0.0 0.4 GO:0030330 DNA damage response, signal transduction by p53 class mediator(GO:0030330)
0.0 1.1 GO:0051693 actin filament capping(GO:0051693)
0.0 0.3 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.5 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 4.5 GO:0006887 exocytosis(GO:0006887)
0.0 1.3 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.8 GO:0046328 regulation of JNK cascade(GO:0046328)
0.0 2.1 GO:0030705 cytoskeleton-dependent intracellular transport(GO:0030705)
0.0 0.5 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 2.4 GO:0042391 regulation of membrane potential(GO:0042391)
0.0 2.8 GO:0006814 sodium ion transport(GO:0006814)
0.0 0.8 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.0 0.4 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 0.3 GO:0007631 feeding behavior(GO:0007631)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 GO:0044316 cone cell pedicle(GO:0044316)
0.7 4.1 GO:0030891 VCB complex(GO:0030891)
0.3 1.1 GO:0008274 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.2 1.5 GO:0005955 calcineurin complex(GO:0005955)
0.2 4.1 GO:0030667 secretory granule membrane(GO:0030667)
0.2 1.1 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.1 1.4 GO:0098982 GABA-ergic synapse(GO:0098982)
0.1 3.3 GO:0043204 perikaryon(GO:0043204)
0.1 0.2 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.1 0.8 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 2.1 GO:0005861 troponin complex(GO:0005861)
0.0 1.2 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 1.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 3.0 GO:0005871 kinesin complex(GO:0005871)
0.0 2.5 GO:0005581 collagen trimer(GO:0005581)
0.0 6.4 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 0.2 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 1.6 GO:0005930 axoneme(GO:0005930)
0.0 0.2 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 1.1 GO:0031902 late endosome membrane(GO:0031902)
0.0 1.1 GO:0005795 Golgi stack(GO:0005795)
0.0 0.4 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.4 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.5 2.2 GO:0008929 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.3 1.2 GO:0015105 arsenite transmembrane transporter activity(GO:0015105)
0.3 1.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.3 1.5 GO:0004126 cytidine deaminase activity(GO:0004126)
0.2 1.5 GO:0033192 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.2 2.7 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.2 3.3 GO:0004383 guanylate cyclase activity(GO:0004383)
0.2 1.1 GO:0017040 ceramidase activity(GO:0017040)
0.1 1.9 GO:0005504 fatty acid binding(GO:0005504)
0.1 1.0 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1 2.4 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 2.1 GO:0005523 tropomyosin binding(GO:0005523)
0.1 2.9 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.1 0.6 GO:0004994 somatostatin receptor activity(GO:0004994)
0.1 1.4 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.1 1.1 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 1.1 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 1.3 GO:0019211 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.1 2.1 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 2.5 GO:0004180 carboxypeptidase activity(GO:0004180)
0.1 0.3 GO:0031843 neuropeptide Y receptor binding(GO:0031841) type 2 neuropeptide Y receptor binding(GO:0031843)
0.0 0.7 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 1.0 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 3.0 GO:0008201 heparin binding(GO:0008201)
0.0 0.8 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 2.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 3.8 GO:0042277 peptide binding(GO:0042277)
0.0 0.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.4 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.5 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 2.4 GO:0015293 symporter activity(GO:0015293)
0.0 0.2 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.0 0.9 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.4 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.0 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.2 2.7 PID CONE PATHWAY Visual signal transduction: Cones
0.1 1.5 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 2.5 NABA COLLAGENS Genes encoding collagen proteins
0.1 0.8 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.6 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 1.2 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.4 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 1.5 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 1.3 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.1 0.8 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 1.2 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 2.1 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 1.0 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 2.5 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 1.1 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 3.4 REACTOME TRANSPORT OF GLUCOSE AND OTHER SUGARS BILE SALTS AND ORGANIC ACIDS METAL IONS AND AMINE COMPOUNDS Genes involved in Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
0.0 1.0 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 1.1 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.6 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.1 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha