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PRJEB1986: zebrafish developmental stages transcriptome

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Results for fli1b

Z-value: 1.28

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Transcription factors associated with fli1b

Gene Symbol Gene ID Gene Info
ENSDARG00000040080 Fli-1 proto-oncogene, ETS transcription factor b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
fli1bdr11_v1_chr16_+_42018367_420183670.652.7e-03Click!

Activity profile of fli1b motif

Sorted Z-values of fli1b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_8129536 3.73 ENSDART00000158112
ENSDART00000011183
protein kinase, cAMP-dependent, catalytic, beta a
chr15_-_4528326 2.91 ENSDART00000158122
ENSDART00000155619
ENSDART00000128602
transcription factor Dp-2
chr5_-_54712159 2.89 ENSDART00000149207
cyclin B1
chr13_+_33651416 2.79 ENSDART00000180221

chr10_+_22775253 2.56 ENSDART00000190141
transmembrane protein 88 a
chr19_-_2231146 2.53 ENSDART00000181909
ENSDART00000043595
twist family bHLH transcription factor 1a
chr5_+_46424437 2.38 ENSDART00000186511
versican a
chr18_+_40381102 2.31 ENSDART00000136588
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D, like
chr20_-_36800002 2.24 ENSDART00000015190
peptidyl-tRNA hydrolase domain containing 1
chr12_+_28955766 2.12 ENSDART00000123417
ENSDART00000139347
zinc finger protein 668
chr1_-_13968153 2.11 ENSDART00000103383
E74-like factor 2b (ets domain transcription factor)
chr22_+_10163901 2.10 ENSDART00000190468
ribonuclease P/MRP 14 subunit
chr7_+_22981909 2.07 ENSDART00000122449
cyclin B3
chr16_-_42013858 2.04 ENSDART00000045403
ets variant 2
chr14_-_41478265 2.03 ENSDART00000149886
ENSDART00000016002
tetraspanin 7
chr16_+_40043673 1.94 ENSDART00000102552
ENSDART00000125484
tRNA methyltransferase 11 homolog (S. cerevisiae)
chr12_-_48312647 1.93 ENSDART00000114415
activating signal cointegrator 1 complex subunit 1
chr7_+_41340520 1.91 ENSDART00000005127
GRB2 associated, regulator of MAPK1
chr20_+_35282682 1.90 ENSDART00000187199
family with sequence similarity 49, member A
chr12_-_35830625 1.88 ENSDART00000180028

chr16_-_34195002 1.85 ENSDART00000054026
regulator of chromosome condensation 1
chr17_+_10242166 1.81 ENSDART00000170420
C-type lectin domain containing 14A
chr24_-_20192996 1.79 ENSDART00000011143
myeloid differentiation primary response 88
chr8_-_25814263 1.75 ENSDART00000143397
TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr6_+_21202639 1.74 ENSDART00000083126
cell death-inducing DFFA-like effector c
chr7_+_20017211 1.74 ENSDART00000100808
B-cell CLL/lymphoma 6, member B
chr2_-_15040345 1.72 ENSDART00000109657
si:dkey-10f21.4
chr8_-_31107537 1.71 ENSDART00000098925
vestigial like 4 like
chr13_-_33700461 1.71 ENSDART00000160520
MAD2L1 binding protein
chr23_-_28025943 1.71 ENSDART00000181146
Sp5 transcription factor-like
chr9_-_24218059 1.70 ENSDART00000007914
nucleic acid binding protein 1a
chr22_-_16291041 1.66 ENSDART00000021666
RNA 3'-terminal phosphate cyclase
chr14_-_26482096 1.65 ENSDART00000187280
SMAD family member 5
chr22_-_23748284 1.61 ENSDART00000162005
complement factor H like 2
chr23_-_21535040 1.61 ENSDART00000010647
regulator of chromosome condensation 2
chr7_+_41314862 1.60 ENSDART00000185198
zgc:165532
chr16_+_42018041 1.60 ENSDART00000134010
ENSDART00000102789
Fli-1 proto-oncogene, ETS transcription factor b
chr18_+_38288877 1.59 ENSDART00000134247
LIM domain only 2 (rhombotin-like 1)
chr6_-_33924883 1.59 ENSDART00000132762
ENSDART00000148142
ENSDART00000142213
aldo-keto reductase family 1, member A1b (aldehyde reductase)
chr1_-_45213565 1.59 ENSDART00000145757
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39Aa
chr19_-_33274978 1.59 ENSDART00000020301
ENSDART00000114714
family with sequence similarity 92, member A1
chr12_+_27462225 1.58 ENSDART00000105661
mesenchyme homeobox 1
chr7_+_16509201 1.57 ENSDART00000173777
zinc finger, DHHC-type containing 13
chr5_-_69716501 1.56 ENSDART00000158956
MOB kinase activator 1A
chr4_+_13909398 1.55 ENSDART00000187959
ENSDART00000184926
periphilin 1
chr7_-_38689562 1.55 ENSDART00000167209
apelin receptor 2
chr9_-_24218367 1.55 ENSDART00000135356
nucleic acid binding protein 1a
chr7_-_66133786 1.54 ENSDART00000154961
BTB (POZ) domain containing 10b
chr18_+_17021391 1.53 ENSDART00000100160
CTF8, chromosome transmission fidelity factor 8 homolog (S. cerevisiae)
chr8_-_7093507 1.52 ENSDART00000045669
si:dkey-222n6.2
chr8_+_18010978 1.50 ENSDART00000039887
ENSDART00000144532
single stranded DNA binding protein 3b
chr3_+_19665319 1.50 ENSDART00000007857
ENSDART00000193509
methyltransferase like 2A
chr9_+_2041535 1.50 ENSDART00000093187
limb and neural patterns a
chr11_-_36350876 1.50 ENSDART00000146495
ENSDART00000020655
proteasome subunit alpha 5
chr8_+_26373149 1.50 ENSDART00000132787
hyaluronoglucosaminidase 3
chr7_-_69025306 1.49 ENSDART00000180796

chr19_-_22843480 1.47 ENSDART00000052503
NudC domain containing 1
chr1_+_43686251 1.44 ENSDART00000074604
ENSDART00000137791
CDGSH iron sulfur domain 2
chr21_+_5080789 1.44 ENSDART00000024199
ATP synthase F1 subunit alpha
chr9_-_31524907 1.44 ENSDART00000142904
ENSDART00000127214
ENSDART00000133427
ENSDART00000146268
ENSDART00000182541
ENSDART00000184736
transmembrane and tetratricopeptide repeat containing 4
chr25_+_18556588 1.42 ENSDART00000073726
caveolin 2
chr1_+_49686408 1.42 ENSDART00000140824
si:ch211-149l1.2
chr1_+_22851261 1.42 ENSDART00000193925
general transcription factor IIE, polypeptide 2, beta
chr20_+_35255403 1.41 ENSDART00000002773
ENSDART00000137915
family with sequence similarity 49, member A
chr12_+_27232173 1.41 ENSDART00000193714
transmembrane protein 106A
chr6_-_40851499 1.39 ENSDART00000182591
RFT1 homolog
chr19_+_1873059 1.39 ENSDART00000145246
small nuclear ribonucleoprotein D1 polypeptide
chr15_-_18176694 1.38 ENSDART00000189840
transmembrane protease, serine 5
chr7_+_41812636 1.38 ENSDART00000174333
origin recognition complex, subunit 6
chr23_+_44374041 1.38 ENSDART00000136056
eph receptor B4b
chr6_-_33925381 1.37 ENSDART00000137268
ENSDART00000145019
ENSDART00000141822
aldo-keto reductase family 1, member A1b (aldehyde reductase)
chr8_+_48943009 1.37 ENSDART00000180763
retention in endoplasmic reticulum sorting receptor 1
chr19_+_10661520 1.36 ENSDART00000091813
ENSDART00000165653
argonaute RISC catalytic component 3b
chr20_-_2619316 1.35 ENSDART00000185777
BUB1 mitotic checkpoint serine/threonine kinase
chr5_-_39171302 1.35 ENSDART00000020808
progestin and adipoQ receptor family member IIIa
chr7_+_22981441 1.34 ENSDART00000182887
cyclin B3
chr7_-_17816175 1.34 ENSDART00000091272
ENSDART00000173757
ECSIT signalling integrator
chr7_+_19374683 1.34 ENSDART00000162700
small nuclear ribonucleoprotein polypeptide F
chr13_+_39532050 1.34 ENSDART00000019379
MARVEL domain containing 1
chr1_-_52498146 1.34 ENSDART00000122217
aspartoacylase (aminocyclase) 3, tandem duplicate 2
chr13_+_5978809 1.33 ENSDART00000102563
ENSDART00000121598
PHD finger protein 10
chr8_-_52715911 1.32 ENSDART00000168241
tubulin, beta 2b
chr2_-_22363460 1.32 ENSDART00000158486
selenoprotein F
chr8_+_18010568 1.32 ENSDART00000121984
single stranded DNA binding protein 3b
chr6_-_10728057 1.32 ENSDART00000002247
Sp3b transcription factor
chr4_-_13973213 1.31 ENSDART00000067177
ENSDART00000144127
prickle homolog 1b
chr2_-_25140022 1.31 ENSDART00000134543
neutral cholesterol ester hydrolase 1a
chr11_+_30647545 1.30 ENSDART00000114792
expressed sequence EH507706
chr5_+_69716458 1.30 ENSDART00000159594
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
chr10_-_40826657 1.29 ENSDART00000076304
proliferating cell nuclear antigen
chr22_+_5135884 1.28 ENSDART00000141276
myeloid-derived growth factor
chr5_+_15495351 1.28 ENSDART00000111646
ENSDART00000114446
SDS3 homolog, SIN3A corepressor complex component
chr16_+_11818126 1.28 ENSDART00000145727
chemokine (C-X-C motif) receptor 3, tandem duplicate 2
chr1_-_22851481 1.26 ENSDART00000054386
quinoid dihydropteridine reductase b1
chr14_-_3381303 1.26 ENSDART00000171601
im:7150988
chr21_-_4793686 1.25 ENSDART00000158232
notch 1a
chr10_+_8875195 1.25 ENSDART00000141045
integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor), tandem duplicate 3
chr23_+_30730121 1.25 ENSDART00000134141
additional sex combs like transcriptional regulator 1
chr3_+_17939828 1.23 ENSDART00000185047
2',3'-cyclic nucleotide 3' phosphodiesterase
chr1_-_44484 1.22 ENSDART00000171547
ENSDART00000164075
ENSDART00000168091
transmembrane protein 39A
chr7_+_56453646 1.22 ENSDART00000112483
solute carrier family 22, member 31
chr13_-_35908275 1.21 ENSDART00000013961
MYCL proto-oncogene, bHLH transcription factor a
chr2_+_38271392 1.21 ENSDART00000042100
homeobox and leucine zipper encoding a
chr5_-_7513082 1.20 ENSDART00000158913
bone morphogenetic protein receptor, type IBa
chr6_+_40775800 1.20 ENSDART00000085090
si:ch211-157b11.8
chr9_+_54179306 1.20 ENSDART00000189829
thymosin, beta 4 x
chr10_+_9553935 1.20 ENSDART00000028855
si:ch211-243g18.2
chr16_+_35401543 1.20 ENSDART00000171608
RAB42, member RAS oncogene family
chr25_+_5015019 1.19 ENSDART00000127600
histone deacetylase 10
chr10_-_11012000 1.19 ENSDART00000132995
adenylate kinase 3
chr12_-_49168398 1.19 ENSDART00000186608

chr19_-_18152407 1.19 ENSDART00000193264
ENSDART00000016135
nuclear factor, erythroid 2-like 3
chr13_+_30903816 1.18 ENSDART00000191727
excision repair cross-complementation group 6
chr13_-_35459928 1.18 ENSDART00000144109
SLX4 interacting protein
chr5_+_37087583 1.18 ENSDART00000049900
transgelin 2
chr13_+_28495419 1.18 ENSDART00000025583
fibroblast growth factor 8a
chr2_+_48288461 1.18 ENSDART00000141495
hes family bHLH transcription factor 6
chr1_+_59146298 1.18 ENSDART00000191885
ENSDART00000152747
G protein-coupled receptor 108
chr20_+_25340814 1.17 ENSDART00000063028
connective tissue growth factor a
chr13_+_32144370 1.17 ENSDART00000020270
odd-skipped related transciption factor 1
chr6_+_3717613 1.17 ENSDART00000184330
Sjogren syndrome antigen B (autoantigen La)
chr21_+_29077509 1.17 ENSDART00000128561
endothelial cell surface expressed chemotaxis and apoptosis regulator
chr21_+_8239544 1.17 ENSDART00000122773
nuclear receptor subfamily 6, group A, member 1b
chr14_+_41345175 1.16 ENSDART00000086104
NADPH oxidase 1
chr2_+_3823813 1.16 ENSDART00000103596
ENSDART00000161880
ENSDART00000185408
Niemann-Pick disease, type C1
chr15_+_30310843 1.16 ENSDART00000112784
LYR motif containing 9
chr21_+_19834072 1.15 ENSDART00000147555
coiled-coil domain containing 80 like 2
chr19_+_1872794 1.15 ENSDART00000013217
small nuclear ribonucleoprotein D1 polypeptide
chr8_-_17997845 1.15 ENSDART00000121660
acyl-CoA thioesterase 11b
chr19_-_34742440 1.14 ENSDART00000122625
ENSDART00000175621
elongator acetyltransferase complex subunit 2
chr16_+_38201840 1.14 ENSDART00000044971
myosin IE, b
chr5_+_30741730 1.14 ENSDART00000098246
ENSDART00000186992
ENSDART00000182533
finTRIM family, member 83
chr18_+_41527877 1.14 ENSDART00000146972
selenoprotein T, 1b
chr12_+_27536270 1.14 ENSDART00000133719
ets variant 4
chr12_+_27537357 1.14 ENSDART00000136212
ets variant 4
chr19_+_47476908 1.13 ENSDART00000157886
zgc:114119
chr16_-_31435020 1.13 ENSDART00000138508
zgc:194210
chr25_-_25575717 1.13 ENSDART00000067138
hypermethylated in cancer 1 like
chr24_-_2423791 1.13 ENSDART00000190402
ras responsive element binding protein 1a
chr7_+_41812817 1.12 ENSDART00000174165
origin recognition complex, subunit 6
chr18_+_7543347 1.11 ENSDART00000103467
ADP-ribosylation factor 5
chr14_-_38828057 1.10 ENSDART00000186088
spindle apparatus coiled-coil protein 1
chr14_-_11456724 1.10 ENSDART00000110424
si:ch211-153b23.4
chr23_-_45318760 1.10 ENSDART00000166883
coiled-coil domain containing 171
chr6_+_40554551 1.10 ENSDART00000017859
ENSDART00000155928
DNA-damage inducible protein 2
chr21_+_11923701 1.09 ENSDART00000109292
ubiquitin associated protein 2a
chr3_-_23512285 1.09 ENSDART00000159151

chr25_-_21031007 1.09 ENSDART00000138985
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide a
chr22_-_23668356 1.09 ENSDART00000167106
ENSDART00000159622
ENSDART00000163228
complement factor H
chr5_+_22133153 1.09 ENSDART00000016214
moesin a
chr4_-_5826320 1.09 ENSDART00000165354
forkhead box M1
chr21_-_22325124 1.09 ENSDART00000142100
glycerophosphodiester phosphodiesterase domain containing 4b
chr5_-_30704390 1.07 ENSDART00000016709
intraflagellar transport 22 homolog (Chlamydomonas)
chr17_-_19535328 1.07 ENSDART00000077809
cytochrome P450, family 26, subfamily C, polypeptide 1
chr14_-_26436951 1.07 ENSDART00000140173
si:dkeyp-110e4.6
chr16_+_40563533 1.06 ENSDART00000190368
tumor protein p53 inducible nuclear protein 1
chr20_+_13883131 1.06 ENSDART00000003248
ENSDART00000152611
NIMA-related kinase 2
chr15_-_23475051 1.06 ENSDART00000152460
NLR family member X1
chr3_-_40528333 1.06 ENSDART00000193047
actin, beta 2
chr21_+_30470809 1.05 ENSDART00000171648
ENSDART00000126678
ENSDART00000003335
ENSDART00000133478
ENSDART00000140811
ENSDART00000147375
sorting nexin 12
chr17_+_24809221 1.05 ENSDART00000082251
ENSDART00000147871
ENSDART00000130871
speedy/RINGO cell cycle regulator family member A
chr17_-_10000339 1.05 ENSDART00000162893
sorting nexin 6
chr5_-_32396929 1.04 ENSDART00000023977
F-box and WD repeat domain containing 2
chr3_-_45281350 1.04 ENSDART00000020168
potassium channel tetramerization domain containing 5a
chr13_-_35765028 1.04 ENSDART00000157391
endoplasmic reticulum lectin 1
chr17_+_24064014 1.04 ENSDART00000182782
ENSDART00000139063
ENSDART00000132755
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2b
chr7_-_26601307 1.04 ENSDART00000188934
phospholipid scramblase 3b
chr13_-_42749916 1.02 ENSDART00000140019
calpain 2, (m/II) large subunit a
chr13_-_7575216 1.02 ENSDART00000159443
paired-like homeodomain 3
chr17_-_33716688 1.02 ENSDART00000043651
dynein, axonemal, light chain 1
chr19_+_42086862 1.02 ENSDART00000151605
nuclear transcription factor Y, gamma
chr8_+_19489854 1.01 ENSDART00000184671
ENSDART00000011258
N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
chr7_+_17543487 1.01 ENSDART00000126652
Danio rerio novel immune-type receptor 1l (nitr1l), mRNA.
chr3_-_36839115 1.01 ENSDART00000154553
receptor (G protein-coupled) activity modifying protein 2
chr15_+_20239141 1.01 ENSDART00000101152
ENSDART00000152473
serine peptidase inhibitor, Kunitz type, 2
chr8_+_30117297 1.01 ENSDART00000077554
Fanconi anemia, complementation group C
chr24_-_31090948 1.01 ENSDART00000176799
holocytochrome c synthase b
chr22_-_14115292 1.01 ENSDART00000105717
ENSDART00000165670
aldehyde oxidase 5
chr10_-_23099809 1.01 ENSDART00000148333
ENSDART00000079703
ENSDART00000162444
notchless homolog 1 (Drosophila)
chr12_-_4301234 1.00 ENSDART00000152377
ENSDART00000152521
carbonic anhydrase XVb
chr9_+_48819280 1.00 ENSDART00000112555
SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr13_-_18195942 1.00 ENSDART00000079902
solute carrier family 25 (mitochondrial carrier; Graves disease autoantigen), member 16
chr21_-_34972872 1.00 ENSDART00000023838
lipase, member Ia
chr1_+_36194761 0.99 ENSDART00000053773
ENSDART00000147458
LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated
chr6_-_55423220 0.98 ENSDART00000158929
cathepsin A
chr20_+_19066858 0.98 ENSDART00000192086
SRY (sex determining region Y)-box 7
chr1_+_16127825 0.98 ENSDART00000122503
tumor suppressor candidate 3
chr1_+_22851745 0.98 ENSDART00000138235
ENSDART00000016488
general transcription factor IIE, polypeptide 2, beta
chr9_+_56232548 0.97 ENSDART00000099276
CCR4-NOT transcription complex, subunit 11
chr10_+_5954787 0.97 ENSDART00000161887
ENSDART00000160345
ENSDART00000190046
mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
chr9_+_34952203 0.97 ENSDART00000121828
ENSDART00000142347
transcription factor Dp-1, a
chr18_-_24988645 0.97 ENSDART00000136434
ENSDART00000085735
chromodomain helicase DNA binding protein 2
chr21_+_27340682 0.96 ENSDART00000011305
dipeptidyl-peptidase 3
chr23_-_9859989 0.95 ENSDART00000005015
protein kinase C binding protein 1, like
chr13_+_24402406 0.94 ENSDART00000043002
RAB1A, member RAS oncogene family b
chr5_-_31875645 0.94 ENSDART00000098160
transmembrane protein 119b
chr7_-_17816921 0.94 ENSDART00000149821
ECSIT signalling integrator
chr19_+_46222918 0.94 ENSDART00000158703
vacuolar protein sorting 28 (yeast)
chr4_-_11064073 0.94 ENSDART00000150760
si:dkey-21h14.8
chr6_+_27992886 0.93 ENSDART00000160354
angiomotin like 2a

Network of associatons between targets according to the STRING database.

First level regulatory network of fli1b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:1905208 negative regulation of striated muscle cell differentiation(GO:0051154) negative regulation of cardiac muscle tissue development(GO:0055026) cardiac muscle cell fate commitment(GO:0060923) canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:0061317) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901296) negative regulation of cardiocyte differentiation(GO:1905208) negative regulation of cardiac muscle cell differentiation(GO:2000726)
0.8 2.4 GO:0003093 renal system process involved in regulation of blood volume(GO:0001977) renal system process involved in regulation of systemic arterial blood pressure(GO:0003071) regulation of glomerular filtration(GO:0003093)
0.6 2.4 GO:0042117 monocyte activation(GO:0042117)
0.5 1.6 GO:2000425 regulation of apoptotic cell clearance(GO:2000425)
0.5 1.5 GO:1903373 regulation of endoplasmic reticulum tubular network organization(GO:1903371) positive regulation of endoplasmic reticulum tubular network organization(GO:1903373)
0.5 0.9 GO:0051148 negative regulation of muscle cell differentiation(GO:0051148)
0.4 4.0 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.4 1.3 GO:0002522 leukocyte migration involved in immune response(GO:0002522)
0.4 1.3 GO:0021531 spinal cord radial glial cell differentiation(GO:0021531)
0.4 1.6 GO:0034087 establishment of mitotic sister chromatid cohesion(GO:0034087) mitotic sister chromatid cohesion, centromeric(GO:0071962)
0.4 2.8 GO:0061635 regulation of protein complex stability(GO:0061635)
0.4 1.6 GO:2000383 ectodermal cell fate commitment(GO:0001712) ectodermal cell fate specification(GO:0001715) ectodermal cell differentiation(GO:0010668) regulation of ectodermal cell fate specification(GO:0042665) regulation of ectoderm development(GO:2000383)
0.4 1.2 GO:0048389 intermediate mesoderm development(GO:0048389)
0.4 1.4 GO:0010259 multicellular organism aging(GO:0010259)
0.3 3.1 GO:0055011 atrial cardiac muscle cell differentiation(GO:0055011)
0.3 1.0 GO:0006043 glucosamine metabolic process(GO:0006041) glucosamine catabolic process(GO:0006043)
0.3 1.0 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.3 1.3 GO:0006272 leading strand elongation(GO:0006272)
0.3 1.6 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.3 1.6 GO:0097355 protein localization to heterochromatin(GO:0097355)
0.3 0.9 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.3 1.5 GO:0031062 positive regulation of histone methylation(GO:0031062)
0.3 0.9 GO:1903173 fatty alcohol metabolic process(GO:1903173)
0.3 1.2 GO:0009447 polyamine catabolic process(GO:0006598) putrescine catabolic process(GO:0009447)
0.3 0.9 GO:1990120 messenger ribonucleoprotein complex assembly(GO:1990120)
0.3 0.3 GO:0071788 endoplasmic reticulum tubular network maintenance(GO:0071788)
0.3 1.7 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.3 0.8 GO:1901890 positive regulation of cell junction assembly(GO:1901890)
0.3 1.6 GO:0051561 positive regulation of mitochondrial calcium ion concentration(GO:0051561)
0.3 0.8 GO:0033690 positive regulation of osteoblast proliferation(GO:0033690)
0.3 1.1 GO:0048211 Golgi vesicle docking(GO:0048211)
0.3 1.8 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
0.3 1.3 GO:0048245 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.2 0.7 GO:0050666 regulation of sulfur amino acid metabolic process(GO:0031335) regulation of homocysteine metabolic process(GO:0050666)
0.2 1.2 GO:0030219 megakaryocyte differentiation(GO:0030219)
0.2 2.3 GO:0061056 sclerotome development(GO:0061056)
0.2 1.6 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.2 0.9 GO:0042779 tRNA 3'-trailer cleavage(GO:0042779)
0.2 1.4 GO:0001937 negative regulation of endothelial cell proliferation(GO:0001937)
0.2 1.0 GO:0017003 protein-heme linkage(GO:0017003) protein-tetrapyrrole linkage(GO:0017006) cytochrome c-heme linkage(GO:0018063)
0.2 0.8 GO:0018343 protein farnesylation(GO:0018343)
0.2 1.4 GO:0006621 protein retention in ER lumen(GO:0006621)
0.2 1.4 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.2 0.6 GO:0021563 glossopharyngeal nerve development(GO:0021563)
0.2 1.5 GO:0042554 superoxide anion generation(GO:0042554)
0.2 0.7 GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732) negative regulation of protein tyrosine kinase activity(GO:0061099)
0.2 1.6 GO:0006465 signal peptide processing(GO:0006465)
0.2 3.9 GO:0010737 protein kinase A signaling(GO:0010737)
0.2 0.9 GO:0019388 galactose catabolic process(GO:0019388) galactose catabolic process via UDP-galactose(GO:0033499)
0.2 6.7 GO:0010389 regulation of G2/M transition of mitotic cell cycle(GO:0010389)
0.2 1.2 GO:0006172 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180)
0.2 1.2 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.2 1.7 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.2 0.8 GO:0048320 axial mesoderm formation(GO:0048320)
0.2 3.3 GO:0045580 regulation of T cell differentiation(GO:0045580)
0.2 1.5 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.2 2.4 GO:0035108 limb morphogenesis(GO:0035108)
0.2 0.6 GO:0042308 regulation of protein import into nucleus(GO:0042306) negative regulation of protein import into nucleus(GO:0042308) negative regulation of nucleocytoplasmic transport(GO:0046823) negative regulation of protein localization to nucleus(GO:1900181) regulation of protein import(GO:1904589) negative regulation of protein import(GO:1904590)
0.2 0.5 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.2 2.4 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.2 4.8 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.1 1.6 GO:2000223 regulation of BMP signaling pathway involved in heart jogging(GO:2000223)
0.1 0.4 GO:0000066 mitochondrial ornithine transport(GO:0000066) mitochondrial L-ornithine transmembrane transport(GO:1990575)
0.1 0.7 GO:1901841 regulation of high voltage-gated calcium channel activity(GO:1901841) negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 2.2 GO:0043248 proteasome assembly(GO:0043248)
0.1 0.6 GO:0016038 absorption of visible light(GO:0016038)
0.1 0.6 GO:0015919 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.1 1.4 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1 2.1 GO:0061055 myotome development(GO:0061055)
0.1 0.5 GO:1900060 regulation of sphingolipid biosynthetic process(GO:0090153) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
0.1 1.4 GO:0072091 regulation of stem cell proliferation(GO:0072091)
0.1 0.5 GO:0015868 intracellular nucleoside transport(GO:0015859) purine nucleoside transmembrane transport(GO:0015860) purine nucleotide transport(GO:0015865) ATP transport(GO:0015867) purine ribonucleotide transport(GO:0015868) adenine nucleotide transport(GO:0051503) mitochondrial ATP transmembrane transport(GO:1990544)
0.1 0.5 GO:0072116 kidney rudiment formation(GO:0072003) pronephros formation(GO:0072116)
0.1 1.4 GO:0046548 retinal rod cell development(GO:0046548)
0.1 0.4 GO:0051177 meiosis II(GO:0007135) meiotic sister chromatid segregation(GO:0045144) meiotic sister chromatid cohesion(GO:0051177)
0.1 0.9 GO:0035627 ceramide transport(GO:0035627)
0.1 1.2 GO:0042989 sequestering of actin monomers(GO:0042989)
0.1 0.5 GO:0046324 regulation of glucose import(GO:0046324)
0.1 1.3 GO:0021535 cell migration in hindbrain(GO:0021535)
0.1 1.5 GO:0043951 regulation of cAMP-mediated signaling(GO:0043949) negative regulation of cAMP-mediated signaling(GO:0043951)
0.1 0.9 GO:0035909 aorta morphogenesis(GO:0035909) dorsal aorta morphogenesis(GO:0035912)
0.1 1.7 GO:0051127 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 1.5 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.1 1.9 GO:0015693 magnesium ion transport(GO:0015693)
0.1 0.4 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.1 1.1 GO:0006450 regulation of translational fidelity(GO:0006450)
0.1 0.9 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.1 0.6 GO:0097101 blood vessel endothelial cell fate specification(GO:0097101)
0.1 1.3 GO:1902101 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.1 0.2 GO:0003097 renal water homeostasis(GO:0003091) renal water transport(GO:0003097)
0.1 0.8 GO:0021550 medulla oblongata development(GO:0021550) dorsal motor nucleus of vagus nerve development(GO:0021744)
0.1 0.7 GO:0006741 NADP biosynthetic process(GO:0006741)
0.1 1.1 GO:0071156 regulation of cell cycle arrest(GO:0071156)
0.1 1.1 GO:0006611 protein export from nucleus(GO:0006611)
0.1 0.6 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.1 0.7 GO:0046070 dGTP catabolic process(GO:0006203) purine nucleoside triphosphate catabolic process(GO:0009146) purine deoxyribonucleoside triphosphate catabolic process(GO:0009217) dGTP metabolic process(GO:0046070)
0.1 2.5 GO:0006270 DNA replication initiation(GO:0006270)
0.1 1.5 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.1 0.9 GO:1902624 positive regulation of neutrophil migration(GO:1902624)
0.1 0.6 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.1 1.3 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.1 2.9 GO:0060037 pharyngeal system development(GO:0060037)
0.1 1.6 GO:0021984 adenohypophysis development(GO:0021984)
0.1 0.6 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.1 0.3 GO:0036336 dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.1 0.4 GO:2001223 negative regulation of neuron migration(GO:2001223)
0.1 0.5 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.1 0.6 GO:0042116 macrophage activation(GO:0042116)
0.1 0.5 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.1 0.5 GO:0071800 podosome assembly(GO:0071800)
0.1 0.2 GO:0097510 base-excision repair, AP site formation via deaminated base removal(GO:0097510)
0.1 1.3 GO:0001936 regulation of endothelial cell proliferation(GO:0001936) positive regulation of endothelial cell proliferation(GO:0001938)
0.1 0.6 GO:0043584 nose development(GO:0043584)
0.1 1.0 GO:0030311 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.1 0.4 GO:0048011 neurotrophin TRK receptor signaling pathway(GO:0048011)
0.1 1.1 GO:0061154 endothelial tube morphogenesis(GO:0061154) blood vessel lumenization(GO:0072554)
0.1 0.5 GO:0090497 mesenchymal cell migration(GO:0090497)
0.1 1.2 GO:0043535 regulation of blood vessel endothelial cell migration(GO:0043535)
0.1 1.0 GO:0036158 outer dynein arm assembly(GO:0036158)
0.1 0.3 GO:0099563 modification of synaptic structure(GO:0099563)
0.1 1.7 GO:0009214 cyclic nucleotide catabolic process(GO:0009214)
0.1 0.4 GO:0035479 angioblast cell migration from lateral mesoderm to midline(GO:0035479)
0.1 1.9 GO:0060840 artery development(GO:0060840)
0.1 0.2 GO:0070166 enamel mineralization(GO:0070166)
0.1 1.4 GO:0002097 tRNA wobble base modification(GO:0002097)
0.1 0.5 GO:0048208 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.1 1.2 GO:0060324 face development(GO:0060324)
0.1 1.6 GO:0045454 cell redox homeostasis(GO:0045454)
0.1 1.4 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1 1.4 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.1 2.8 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.1 2.5 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.1 0.2 GO:0002637 regulation of immunoglobulin production(GO:0002637) positive regulation of immunoglobulin production(GO:0002639)
0.1 0.1 GO:0021501 prechordal plate formation(GO:0021501)
0.1 0.3 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498) protein ufmylation(GO:0071569) protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.1 0.2 GO:1903537 meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.1 0.6 GO:0060021 palate development(GO:0060021)
0.0 0.3 GO:1900028 negative regulation of Rac protein signal transduction(GO:0035021) wound healing, spreading of epidermal cells(GO:0035313) negative regulation of ruffle assembly(GO:1900028)
0.0 0.7 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.5 GO:0031269 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.3 GO:0097534 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
0.0 0.7 GO:0046051 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.0 0.4 GO:0006449 regulation of translational termination(GO:0006449)
0.0 1.4 GO:0006406 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 1.1 GO:0071910 determination of liver left/right asymmetry(GO:0071910)
0.0 1.5 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 1.2 GO:0048263 determination of dorsal identity(GO:0048263)
0.0 0.2 GO:2001046 positive regulation of integrin-mediated signaling pathway(GO:2001046)
0.0 0.8 GO:0008354 germ cell migration(GO:0008354)
0.0 0.2 GO:1903523 negative regulation of heart contraction(GO:0045822) negative regulation of blood circulation(GO:1903523)
0.0 0.3 GO:0031179 peptide modification(GO:0031179)
0.0 0.7 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 2.4 GO:0016575 histone deacetylation(GO:0016575)
0.0 1.0 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.3 GO:1902038 positive regulation of hematopoietic stem cell differentiation(GO:1902038)
0.0 0.7 GO:0033077 T cell differentiation in thymus(GO:0033077) thymocyte aggregation(GO:0071594)
0.0 0.2 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.9 GO:1902653 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.0 0.3 GO:0055090 acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
0.0 0.6 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.0 0.7 GO:0051351 positive regulation of ligase activity(GO:0051351)
0.0 1.0 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 1.0 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.0 0.3 GO:0032099 negative regulation of response to food(GO:0032096) negative regulation of appetite(GO:0032099)
0.0 0.3 GO:0010889 regulation of sequestering of triglyceride(GO:0010889) positive regulation of sequestering of triglyceride(GO:0010890) sequestering of triglyceride(GO:0030730)
0.0 0.8 GO:0030518 intracellular steroid hormone receptor signaling pathway(GO:0030518)
0.0 1.9 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 0.2 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.0 0.7 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.0 1.7 GO:0006352 DNA-templated transcription, initiation(GO:0006352)
0.0 0.1 GO:0000390 spliceosomal complex disassembly(GO:0000390)
0.0 0.1 GO:0042560 10-formyltetrahydrofolate metabolic process(GO:0009256) 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
0.0 1.0 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 1.8 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.2 GO:0032218 riboflavin transport(GO:0032218)
0.0 0.7 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.3 GO:0031577 mitotic spindle assembly checkpoint(GO:0007094) spindle checkpoint(GO:0031577) negative regulation of mitotic metaphase/anaphase transition(GO:0045841) spindle assembly checkpoint(GO:0071173) mitotic spindle checkpoint(GO:0071174)
0.0 0.8 GO:0051294 establishment of spindle orientation(GO:0051294)
0.0 0.8 GO:0070831 basement membrane assembly(GO:0070831)
0.0 0.4 GO:0045740 positive regulation of DNA replication(GO:0045740)
0.0 0.7 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 2.1 GO:0071559 transforming growth factor beta receptor signaling pathway(GO:0007179) response to transforming growth factor beta(GO:0071559) cellular response to transforming growth factor beta stimulus(GO:0071560)
0.0 0.2 GO:0035476 angioblast cell migration(GO:0035476)
0.0 0.2 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.6 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.3 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 2.8 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0 0.1 GO:0046632 alpha-beta T cell differentiation(GO:0046632)
0.0 1.1 GO:0031647 regulation of protein stability(GO:0031647)
0.0 1.1 GO:0070830 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.0 1.3 GO:0035825 reciprocal DNA recombination(GO:0035825)
0.0 0.5 GO:0042953 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.0 0.4 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.6 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.8 GO:0001706 endoderm formation(GO:0001706)
0.0 1.0 GO:0007173 epidermal growth factor receptor signaling pathway(GO:0007173)
0.0 2.5 GO:0008033 tRNA processing(GO:0008033)
0.0 1.1 GO:0010842 retina layer formation(GO:0010842)
0.0 0.5 GO:1904894 positive regulation of JAK-STAT cascade(GO:0046427) positive regulation of STAT cascade(GO:1904894)
0.0 2.1 GO:0008285 negative regulation of cell proliferation(GO:0008285)
0.0 0.3 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.0 0.5 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.0 0.3 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 0.1 GO:0042364 water-soluble vitamin biosynthetic process(GO:0042364)
0.0 0.9 GO:0035082 axoneme assembly(GO:0035082)
0.0 0.4 GO:0048010 vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.0 0.1 GO:0061316 canonical Wnt signaling pathway involved in heart development(GO:0061316) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
0.0 0.1 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
0.0 0.2 GO:0030878 thyroid gland development(GO:0030878)
0.0 0.2 GO:0051121 lipoxygenase pathway(GO:0019372) linoleic acid metabolic process(GO:0043651) hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.1 GO:0019563 glycerol catabolic process(GO:0019563)
0.0 1.0 GO:0031623 receptor internalization(GO:0031623)
0.0 0.9 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 0.3 GO:0021988 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.0 0.1 GO:0032119 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.0 0.4 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.4 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.0 0.3 GO:0016203 muscle attachment(GO:0016203)
0.0 0.4 GO:0007568 aging(GO:0007568)
0.0 0.2 GO:0002574 thrombocyte differentiation(GO:0002574)
0.0 0.4 GO:0048332 mesoderm morphogenesis(GO:0048332)
0.0 0.3 GO:0006144 purine nucleobase metabolic process(GO:0006144)
0.0 0.3 GO:0030500 regulation of bone mineralization(GO:0030500) regulation of biomineral tissue development(GO:0070167)
0.0 1.6 GO:0071466 cellular response to xenobiotic stimulus(GO:0071466)
0.0 0.5 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.1 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 3.1 GO:0000122 negative regulation of transcription from RNA polymerase II promoter(GO:0000122)
0.0 0.4 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.1 GO:0006116 NADH oxidation(GO:0006116) glycerol-3-phosphate catabolic process(GO:0046168)
0.0 0.1 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.0 0.9 GO:0031018 endocrine pancreas development(GO:0031018)
0.0 0.4 GO:0001570 vasculogenesis(GO:0001570)
0.0 0.3 GO:0050727 regulation of inflammatory response(GO:0050727)
0.0 0.3 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.7 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 2.8 GO:0032259 methylation(GO:0032259)
0.0 2.8 GO:0045892 negative regulation of transcription, DNA-templated(GO:0045892)
0.0 0.2 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.5 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.2 GO:0090481 pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.0 0.1 GO:0046512 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0 0.4 GO:0030917 midbrain-hindbrain boundary development(GO:0030917)
0.0 0.7 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.0 3.2 GO:0046777 protein autophosphorylation(GO:0046777)
0.0 0.2 GO:0030851 granulocyte differentiation(GO:0030851)
0.0 0.3 GO:0030322 stabilization of membrane potential(GO:0030322)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 2.9 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.5 3.2 GO:0070876 SOSS complex(GO:0070876)
0.5 1.5 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.5 1.5 GO:0098826 endoplasmic reticulum tubular network membrane(GO:0098826)
0.5 3.5 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.5 2.4 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.4 1.6 GO:0005787 signal peptidase complex(GO:0005787)
0.3 1.6 GO:0031415 NatA complex(GO:0031415)
0.3 1.2 GO:0035301 Hedgehog signaling complex(GO:0035301)
0.3 0.9 GO:0042382 paraspeckles(GO:0042382)
0.3 1.3 GO:0097433 dense body(GO:0097433)
0.2 1.7 GO:0072487 MSL complex(GO:0072487)
0.2 2.5 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.2 1.4 GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.2 0.6 GO:0097361 CIA complex(GO:0097361)
0.2 0.8 GO:0016600 flotillin complex(GO:0016600)
0.2 0.8 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.2 1.5 GO:0043020 NADPH oxidase complex(GO:0043020)
0.2 0.9 GO:1990131 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.2 1.3 GO:0035517 PR-DUB complex(GO:0035517)
0.2 0.5 GO:0042709 succinate-CoA ligase complex(GO:0042709)
0.2 1.9 GO:0045095 keratin filament(GO:0045095)
0.2 1.4 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.2 1.7 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.2 1.0 GO:0031262 Ndc80 complex(GO:0031262)
0.2 1.3 GO:0001772 immunological synapse(GO:0001772)
0.2 1.6 GO:0005688 U6 snRNP(GO:0005688)
0.2 0.9 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 1.5 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 0.4 GO:1990879 CST complex(GO:1990879)
0.1 0.5 GO:0035339 SPOTS complex(GO:0035339)
0.1 1.5 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.1 1.9 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 2.2 GO:0005685 U1 snRNP(GO:0005685)
0.1 0.5 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1 1.3 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 1.1 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 0.3 GO:1902560 GMP reductase complex(GO:1902560)
0.1 0.4 GO:0032584 growth cone membrane(GO:0032584)
0.1 1.2 GO:0030904 retromer complex(GO:0030904)
0.1 1.0 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 1.0 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 0.5 GO:0070390 transcription export complex 2(GO:0070390)
0.1 4.7 GO:0030496 midbody(GO:0030496)
0.1 0.9 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1 0.6 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.1 1.2 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 1.3 GO:0071564 npBAF complex(GO:0071564)
0.1 1.6 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 1.1 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 1.1 GO:0002102 podosome(GO:0002102)
0.1 1.1 GO:0044545 NSL complex(GO:0044545)
0.1 1.4 GO:0000780 condensed nuclear chromosome kinetochore(GO:0000778) condensed nuclear chromosome, centromeric region(GO:0000780)
0.1 1.6 GO:0070822 Sin3-type complex(GO:0070822)
0.1 0.7 GO:0070449 elongin complex(GO:0070449)
0.1 0.6 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1 1.2 GO:0000813 ESCRT I complex(GO:0000813)
0.1 0.7 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 0.9 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 0.2 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
0.1 1.0 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 0.4 GO:0034990 nuclear cohesin complex(GO:0000798) mitotic cohesin complex(GO:0030892) nuclear mitotic cohesin complex(GO:0034990) nuclear meiotic cohesin complex(GO:0034991)
0.1 1.0 GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.1 0.5 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.8 GO:0031209 SCAR complex(GO:0031209)
0.0 1.5 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 1.6 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.9 GO:0034399 nuclear periphery(GO:0034399)
0.0 2.1 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 1.3 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.7 GO:0030315 T-tubule(GO:0030315)
0.0 5.9 GO:0016324 apical plasma membrane(GO:0016324)
0.0 1.0 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 1.4 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 0.4 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.7 GO:0005838 proteasome regulatory particle(GO:0005838)
0.0 1.1 GO:0005940 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.3 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 1.2 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.6 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.6 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.3 GO:0032021 NELF complex(GO:0032021)
0.0 0.6 GO:0005605 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.0 0.5 GO:0043209 myelin sheath(GO:0043209)
0.0 1.2 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.4 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.6 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 3.2 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 1.9 GO:0032592 integral component of mitochondrial membrane(GO:0032592)
0.0 1.6 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.5 GO:0016282 eukaryotic 43S preinitiation complex(GO:0016282)
0.0 0.3 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 2.4 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.1 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 1.5 GO:0005814 centriole(GO:0005814)
0.0 0.4 GO:0044327 dendritic spine head(GO:0044327)
0.0 5.7 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.1 GO:0016460 myosin II complex(GO:0016460)
0.0 1.1 GO:0030286 dynein complex(GO:0030286)
0.0 0.1 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 1.2 GO:0031228 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 1.7 GO:0005795 Golgi stack(GO:0005795)
0.0 0.1 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.3 GO:0032039 integrator complex(GO:0032039)
0.0 0.2 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.5 GO:0016605 PML body(GO:0016605)
0.0 0.6 GO:0005811 lipid particle(GO:0005811)
0.0 0.6 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.2 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.2 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.3 GO:0032040 small-subunit processome(GO:0032040)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.7 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.7 2.0 GO:0004113 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity(GO:0004113)
0.6 1.8 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.6 3.0 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.5 1.9 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.4 1.5 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.4 1.4 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.3 1.7 GO:0001223 transcription coactivator binding(GO:0001223)
0.3 1.0 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.3 1.0 GO:0016623 aldehyde oxidase activity(GO:0004031) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.3 1.7 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
0.3 2.2 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.3 1.5 GO:0060182 apelin receptor activity(GO:0060182)
0.3 1.2 GO:0047611 acetylspermidine deacetylase activity(GO:0047611)
0.3 2.4 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.3 1.1 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.3 3.0 GO:0004046 aminoacylase activity(GO:0004046)
0.3 1.3 GO:0008430 selenium binding(GO:0008430)
0.3 1.3 GO:0098973 structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.3 1.3 GO:0019863 IgE binding(GO:0019863) immunoglobulin binding(GO:0019865)
0.3 2.0 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.3 1.3 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.2 1.7 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.2 0.9 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.2 1.3 GO:0061133 endopeptidase activator activity(GO:0061133)
0.2 1.0 GO:0004408 holocytochrome-c synthase activity(GO:0004408)
0.2 0.6 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.2 1.8 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.2 0.8 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.2 0.6 GO:0045545 syndecan binding(GO:0045545)
0.2 0.5 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.2 0.5 GO:0004774 succinate-CoA ligase activity(GO:0004774) succinate-CoA ligase (ADP-forming) activity(GO:0004775) succinate-CoA ligase (GDP-forming) activity(GO:0004776)
0.2 0.9 GO:1902387 ceramide transporter activity(GO:0035620) ceramide 1-phosphate binding(GO:1902387) ceramide 1-phosphate transporter activity(GO:1902388)
0.2 2.1 GO:0004526 ribonuclease P activity(GO:0004526)
0.2 1.7 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.2 1.2 GO:0019809 spermidine binding(GO:0019809)
0.2 1.4 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.2 1.7 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 0.4 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.1 0.4 GO:0043621 protein self-association(GO:0043621)
0.1 0.6 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1 1.3 GO:0004488 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
0.1 0.9 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.1 0.7 GO:0004122 cystathionine beta-synthase activity(GO:0004122)
0.1 1.4 GO:0035198 miRNA binding(GO:0035198)
0.1 0.9 GO:0030274 LIM domain binding(GO:0030274)
0.1 0.5 GO:0005471 ATP:ADP antiporter activity(GO:0005471)
0.1 0.8 GO:1903924 estradiol binding(GO:1903924)
0.1 2.5 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 0.7 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.1 1.1 GO:0043515 kinetochore binding(GO:0043515)
0.1 1.8 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 0.8 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 1.5 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.1 0.3 GO:0003920 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.1 0.3 GO:0015462 protein-transmembrane transporting ATPase activity(GO:0015462)
0.1 0.7 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.1 1.4 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 1.0 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.1 1.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 0.7 GO:0001727 lipid kinase activity(GO:0001727)
0.1 0.5 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 0.3 GO:0052717 tRNA-specific adenosine-34 deaminase activity(GO:0052717)
0.1 0.3 GO:0001635 adrenomedullin receptor activity(GO:0001605) calcitonin gene-related peptide receptor activity(GO:0001635)
0.1 0.8 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.1 1.3 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1 1.2 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 1.2 GO:0005537 mannose binding(GO:0005537)
0.1 0.3 GO:0071568 UFM1 transferase activity(GO:0071568)
0.1 0.9 GO:0017091 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 1.0 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 0.8 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.1 1.6 GO:0070411 I-SMAD binding(GO:0070411)
0.1 0.2 GO:0004394 heparan sulfate 2-O-sulfotransferase activity(GO:0004394)
0.1 1.0 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.1 0.7 GO:0008172 S-methyltransferase activity(GO:0008172)
0.1 0.4 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.1 0.3 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.1 1.8 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.1 0.8 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.1 6.4 GO:0003697 single-stranded DNA binding(GO:0003697)
0.1 0.7 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.1 1.6 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.1 4.1 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 1.4 GO:0005003 ephrin receptor activity(GO:0005003)
0.1 0.9 GO:0051117 ATPase binding(GO:0051117)
0.1 1.1 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1 0.5 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.2 GO:0030331 estrogen receptor binding(GO:0030331)
0.1 0.2 GO:0052855 ATP-dependent NAD(P)H-hydrate dehydratase activity(GO:0047453) ADP-dependent NAD(P)H-hydrate dehydratase activity(GO:0052855)
0.1 0.8 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 1.0 GO:0015026 coreceptor activity(GO:0015026)
0.1 1.0 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 0.9 GO:0045159 myosin II binding(GO:0045159)
0.1 0.2 GO:0000996 core DNA-dependent RNA polymerase binding promoter specificity activity(GO:0000996) mitochondrial RNA polymerase binding promoter specificity activity(GO:0034246)
0.1 0.3 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.1 1.0 GO:0097602 cullin family protein binding(GO:0097602)
0.1 0.7 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.1 1.3 GO:0005112 Notch binding(GO:0005112)
0.0 0.4 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.2 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 1.4 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 1.6 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 0.6 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 1.3 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.7 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.6 GO:0055102 phospholipase inhibitor activity(GO:0004859) lipase inhibitor activity(GO:0055102)
0.0 1.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 2.8 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 4.0 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.3 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.7 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.5 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.4 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.3 GO:0000048 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.0 6.3 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.7 GO:0003785 actin monomer binding(GO:0003785)
0.0 1.0 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.2 GO:0032217 riboflavin transporter activity(GO:0032217)
0.0 0.7 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.1 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.4 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.5 GO:0002039 p53 binding(GO:0002039)
0.0 1.0 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.2 GO:0046592 polyamine oxidase activity(GO:0046592)
0.0 0.5 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.6 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.2 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.2 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.8 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.0 0.1 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.0 0.6 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.5 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.0 1.3 GO:0051536 iron-sulfur cluster binding(GO:0051536) metal cluster binding(GO:0051540)
0.0 0.7 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 1.1 GO:0000049 tRNA binding(GO:0000049)
0.0 0.2 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 0.5 GO:0004860 protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210)
0.0 0.3 GO:0005522 profilin binding(GO:0005522)
0.0 0.6 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.7 GO:0008378 galactosyltransferase activity(GO:0008378)
0.0 0.5 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.5 GO:0033549 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) MAP kinase phosphatase activity(GO:0033549)
0.0 0.5 GO:0031369 translation initiation factor binding(GO:0031369)
0.0 0.8 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.2 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.4 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 1.1 GO:0005347 ATP transmembrane transporter activity(GO:0005347)
0.0 0.1 GO:0043185 vascular endothelial growth factor receptor 3 binding(GO:0043185)
0.0 0.1 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.9 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
0.0 2.9 GO:0004386 helicase activity(GO:0004386)
0.0 0.3 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.3 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.5 GO:0004697 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.0 5.6 GO:0003682 chromatin binding(GO:0003682)
0.0 0.2 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.1 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.1 GO:0051920 peroxiredoxin activity(GO:0051920)
0.0 0.2 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.0 0.4 GO:0031543 peptidyl-proline dioxygenase activity(GO:0031543)
0.0 0.2 GO:0043028 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.0 0.5 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.3 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0 0.8 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.1 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0 2.3 GO:0060090 binding, bridging(GO:0060090)
0.0 0.2 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.5 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.2 GO:0004844 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0 0.1 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.6 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.6 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 24.3 GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
0.0 0.6 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.6 GO:0005507 copper ion binding(GO:0005507)
0.0 1.1 GO:0042393 histone binding(GO:0042393)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 0.4 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.2 2.5 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.2 2.8 PID ALK2 PATHWAY ALK2 signaling events
0.1 1.0 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 4.2 PID PLK1 PATHWAY PLK1 signaling events
0.1 1.8 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 1.7 PID MYC PATHWAY C-MYC pathway
0.1 3.3 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 2.5 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.1 0.7 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 2.1 PID BARD1 PATHWAY BARD1 signaling events
0.1 4.4 PID E2F PATHWAY E2F transcription factor network
0.1 0.4 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 0.2 PID IFNG PATHWAY IFN-gamma pathway
0.0 1.2 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.8 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 1.5 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 1.9 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.2 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 1.2 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.6 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.5 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.6 PID ARF 3PATHWAY Arf1 pathway
0.0 0.4 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 1.0 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.7 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.5 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.5 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.9 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.4 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 1.0 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.4 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.9 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.3 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 1.4 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.3 PID ATM PATHWAY ATM pathway
0.0 0.2 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.2 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.9 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.2 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.4 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.2 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.3 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.2 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.1 PID CD40 PATHWAY CD40/CD40L signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 5.4 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.3 1.1 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.2 0.6 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.2 1.8 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.1 1.6 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.1 1.5 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.1 1.6 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 1.9 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.1 4.1 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.1 1.3 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.1 0.9 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 0.4 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 2.0 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.1 1.3 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.1 0.5 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.1 2.8 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.1 0.8 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 1.6 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 0.4 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.1 1.7 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.1 1.0 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 0.4 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 0.5 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 2.0 REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.1 1.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 4.8 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 3.2 REACTOME RIG I MDA5 MEDIATED INDUCTION OF IFN ALPHA BETA PATHWAYS Genes involved in RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
0.1 1.0 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 1.0 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.1 2.2 REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.1 0.5 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 1.7 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.1 1.0 REACTOME LATE PHASE OF HIV LIFE CYCLE Genes involved in Late Phase of HIV Life Cycle
0.0 0.6 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.7 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 0.4 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 0.3 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.2 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.7 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.7 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.5 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.7 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.6 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 1.0 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.5 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.6 REACTOME FGFR LIGAND BINDING AND ACTIVATION Genes involved in FGFR ligand binding and activation
0.0 0.7 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 1.5 REACTOME TRAF6 MEDIATED INDUCTION OF NFKB AND MAP KINASES UPON TLR7 8 OR 9 ACTIVATION Genes involved in TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation
0.0 1.0 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.3 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.6 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.3 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.4 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 0.4 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.2 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.7 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.1 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.1 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.2 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.7 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.2 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.2 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 1.0 REACTOME ASPARAGINE N LINKED GLYCOSYLATION Genes involved in Asparagine N-linked glycosylation
0.0 0.3 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.2 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.2 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.6 REACTOME DNA REPAIR Genes involved in DNA Repair