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PRJEB1986: zebrafish developmental stages transcriptome

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Results for crx+otx1

Z-value: 1.17

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Transcription factors associated with crx+otx1

Gene Symbol Gene ID Gene Info
ENSDARG00000011989 cone-rod homeobox
ENSDARG00000094992 orthodenticle homeobox 1
ENSDARG00000113850 cone-rod homeobox

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
otx1dr11_v1_chr17_+_24320861_24320861-0.716.0e-04Click!
crxdr11_v1_chr5_+_36932718_369327180.077.7e-01Click!

Activity profile of crx+otx1 motif

Sorted Z-values of crx+otx1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr21_+_13366353 4.21 ENSDART00000151630
si:ch73-62l21.1
chr4_+_68562464 3.41 ENSDART00000192954

chr1_+_5576151 3.17 ENSDART00000109756
carboxypeptidase O
chr4_-_16853464 3.12 ENSDART00000125743
ENSDART00000164570
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3a
chr6_+_54538948 3.10 ENSDART00000149270
tubby like protein 1b
chr1_-_58766424 2.56 ENSDART00000191010

chr17_+_30448452 2.54 ENSDART00000153939
lipin 1
chr19_-_5207361 2.53 ENSDART00000174611
syntaxin 1B
chr10_+_17026870 2.51 ENSDART00000184529
ENSDART00000157480

chr6_-_16406210 2.46 ENSDART00000012023
Fas apoptotic inhibitory molecule b
chr10_-_35108683 2.42 ENSDART00000049633
zgc:110006
chr25_-_19090479 2.27 ENSDART00000027465
ENSDART00000177670
calcium channel, voltage-dependent, alpha 2/delta subunit 4b
chr7_+_19903924 2.26 ENSDART00000159112
si:ch211-285j22.3
chr8_-_46572298 2.20 ENSDART00000030470
sulfotransferase family 1, cytosolic sulfotransferase 3
chr11_-_37693019 2.20 ENSDART00000102898
zgc:158258
chr3_+_29980603 2.08 ENSDART00000151509
potassium voltage-gated channel, shaker-related subfamily, member 7
chr17_-_51202339 2.01 ENSDART00000167117
si:ch1073-469d17.2
chr7_-_39378903 2.00 ENSDART00000173659
solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
chr3_+_62000822 1.95 ENSDART00000106680
retinoic acid induced 1
chr24_+_35975398 1.92 ENSDART00000173058
obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF b
chr18_+_10784730 1.90 ENSDART00000028938
microtubule associated monooxygenase, calponin and LIM domain containing 3a
chr24_-_38079261 1.88 ENSDART00000105662
C-reactive protein 1
chr4_+_72797711 1.87 ENSDART00000190934
ENSDART00000163236
myelin regulatory factor-like
chr17_+_50701748 1.87 ENSDART00000191938
ENSDART00000183220
ENSDART00000049464
fermitin family member 2
chr18_+_50089000 1.86 ENSDART00000058936
secretory carrier membrane protein 5b
chr4_+_7841627 1.85 ENSDART00000037997
upper zone of growth plate and cartilage matrix associated a
chr22_+_17203752 1.85 ENSDART00000143376
RAB3B, member RAS oncogene family
chr5_-_69180587 1.83 ENSDART00000156681
ENSDART00000160753
zgc:171967
chr16_+_4055331 1.83 ENSDART00000128978

chr18_-_8579907 1.79 ENSDART00000147284
si:ch211-220f12.1
chr21_-_28340977 1.79 ENSDART00000141629
neurexin 2a
chr1_+_23162124 1.78 ENSDART00000188428
si:dkey-92j12.5
chr7_+_19904136 1.77 ENSDART00000173452
si:ch211-285j22.3
chr20_+_46560258 1.71 ENSDART00000122115
si:ch211-153j24.3
chr12_+_2660733 1.68 ENSDART00000152235
interphotoreceptor retinoid-binding protein like
chr23_+_7710721 1.68 ENSDART00000186852
ENSDART00000161193
kinesin family member 3B
chr3_+_15296824 1.65 ENSDART00000043801
calcium binding protein 5b
chr23_+_5465806 1.61 ENSDART00000149434
ENSDART00000148506
tubby like protein 1a
chr24_-_31140356 1.61 ENSDART00000167837
transmembrane protein 56a
chr1_-_58009216 1.60 ENSDART00000143829
nucleoredoxin like 1
chr9_-_55744713 1.58 ENSDART00000157570
acetylserotonin O-methyltransferase
chr11_+_6295370 1.55 ENSDART00000139882
RAN binding protein 3a
chr19_+_14921000 1.47 ENSDART00000144052
opioid receptor, delta 1a
chr23_+_39963599 1.45 ENSDART00000166539
FYVE and coiled-coil domain containing 1a
chr18_+_3634652 1.44 ENSDART00000159913
leucine-rich repeats and calponin homology (CH) domain containing 3
chr6_-_28980756 1.44 ENSDART00000014661
glomulin, FKBP associated protein b
chr1_-_24349759 1.42 ENSDART00000142740
ENSDART00000177989
LPS-responsive vesicle trafficking, beach and anchor containing
chr12_-_35883814 1.40 ENSDART00000177986
ENSDART00000129888
centrosomal protein 131
chr19_+_7152966 1.40 ENSDART00000080348
bromodomain containing 2a
chr2_-_51757328 1.40 ENSDART00000189286
si:ch211-9d9.1
chr7_+_67486807 1.37 ENSDART00000159989
copine VII
chr18_-_8030073 1.35 ENSDART00000151490
SH3 and multiple ankyrin repeat domains 3a
chr3_+_22327738 1.35 ENSDART00000055675
growth hormone 1
chr8_+_2656231 1.34 ENSDART00000160833
family with sequence similarity 102, member Aa
chr25_-_204019 1.30 ENSDART00000188440
ENSDART00000191735

chr11_-_3366782 1.29 ENSDART00000127982
sulfite oxidase
chr20_+_2134816 1.28 ENSDART00000039249
l(3)mbt-like 3 (Drosophila)
chr16_+_46497149 1.27 ENSDART00000135151
ENSDART00000058324
rapunzel 4
chr17_-_29194219 1.27 ENSDART00000157340
spectrin, beta, non-erythrocytic 5
chr16_+_43219363 1.25 ENSDART00000183610
ADAM metallopeptidase domain 22
chr5_-_69180227 1.24 ENSDART00000154816
zgc:171967
chr13_-_40499296 1.24 ENSDART00000158338
Danio rerio cyclin and CBS domain divalent metal cation transport mediator 1 (cnnm1), mRNA.
chr1_-_43712120 1.22 ENSDART00000074600
si:dkey-162b23.4
chr2_+_20430366 1.22 ENSDART00000155108
si:ch211-153l6.6
chr3_-_3366590 1.22 ENSDART00000109428
ENSDART00000175329
si:dkey-46g23.1
chr2_-_26499842 1.21 ENSDART00000186929

chr10_+_4875262 1.21 ENSDART00000165942
paralemmin 2
chr11_+_29770966 1.19 ENSDART00000088624
ENSDART00000124471
retinitis pigmentosa GTPase regulator b
chr14_+_11909966 1.19 ENSDART00000171829
FERM and PDZ domain containing 3
chr21_-_39058490 1.15 ENSDART00000114885
aldehyde dehydrogenase 3 family, member A2b
chr17_-_7371564 1.15 ENSDART00000060336
RAB32b, member RAS oncogene family
chr2_+_49417900 1.13 ENSDART00000122742
ENSDART00000160783
RAR-related orphan receptor C b
chr20_+_13969414 1.07 ENSDART00000049864
retinal degeneration 3
chr21_+_31838386 1.06 ENSDART00000135591
si:ch211-12m10.1
chr9_-_1459985 1.05 ENSDART00000124777
oxysterol binding protein-like 6
chr10_+_40235959 1.05 ENSDART00000145862
GRAM domain containing 1Ba
chr9_+_10014817 1.04 ENSDART00000132065
neurexophilin 2a
chr23_+_1181248 1.02 ENSDART00000170942
utrophin
chr24_+_9475809 1.02 ENSDART00000132688
si:ch211-285f17.1
chr13_-_36050303 1.02 ENSDART00000134955
ENSDART00000139087
legumain
chr12_+_23850661 1.01 ENSDART00000152921
supervillin a
chr22_+_5176693 1.00 ENSDART00000160927
ceramide synthase 1
chr22_+_5176255 0.98 ENSDART00000092647
ceramide synthase 1
chr11_-_15090564 0.95 ENSDART00000162079
solute carrier family 1 (glutamate transporter), member 8a
chr19_+_48176745 0.95 ENSDART00000164963
PR domain containing 1b, with ZNF domain
chr17_-_31058900 0.95 ENSDART00000134998
ENSDART00000104307
ENSDART00000172721
echinoderm microtubule associated protein like 1
chr8_-_19649617 0.90 ENSDART00000189033
family with sequence similarity 78, member B b
chr9_+_10014514 0.90 ENSDART00000185590
neurexophilin 2a
chr3_-_13068189 0.88 ENSDART00000167180
protein kinase, cAMP-dependent, regulatory, type I, beta
chr8_-_51806584 0.85 ENSDART00000146976
si:ch73-313l22.2
chr9_+_17982737 0.82 ENSDART00000192569
A kinase (PRKA) anchor protein 11
chr21_-_40562705 0.80 ENSDART00000158289
ENSDART00000171997
TAO kinase 1b
chr14_-_6402769 0.79 ENSDART00000121552
solute carrier family 44 (choline transporter), member 1b
chr5_+_9434288 0.78 ENSDART00000162089
UDP glucuronosyltransferase 2 family, polypeptide A7
chr13_+_733027 0.78 ENSDART00000149547
neurexin 1b
chr8_+_28724692 0.78 ENSDART00000140115
coiled-coil serine-rich protein 1
chr3_-_30218504 0.77 ENSDART00000103487
zgc:195001
chr23_+_45512825 0.77 ENSDART00000064846
PRELI domain containing 1b
chr13_+_2442841 0.75 ENSDART00000114456
ENSDART00000137124
ENSDART00000193737
ENSDART00000189722
ENSDART00000187485
ARFGEF family member 3
chr14_-_31694274 0.75 ENSDART00000173353
MAP7 domain containing 3
chr2_+_30721070 0.74 ENSDART00000099052
si:dkey-94e7.2
chr14_+_2487672 0.72 ENSDART00000170629
ENSDART00000123063
fibroblast growth factor 18a
chr7_-_38340674 0.72 ENSDART00000075782
solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10a
chr10_-_42898220 0.72 ENSDART00000099270

chr15_+_46605482 0.71 ENSDART00000184449

chr22_+_30047245 0.71 ENSDART00000142857
ENSDART00000141247
ENSDART00000140015
ENSDART00000040538
adducin 3 (gamma) a
chr21_-_2209012 0.69 ENSDART00000158345
zgc:162971
chr4_+_33537372 0.69 ENSDART00000181450
si:dkey-84h14.2
chr9_-_5318873 0.69 ENSDART00000129308
activin A receptor type 1C
chr9_-_46276626 0.69 ENSDART00000165238
histone deacetylase 4
chr12_+_49100365 0.68 ENSDART00000171905

chr25_-_10629940 0.67 ENSDART00000154483
ENSDART00000155231
protein phosphatase 6, regulatory subunit 3
chr6_-_10168822 0.66 ENSDART00000151016
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1a
chr9_-_135774 0.66 ENSDART00000160435

chr4_+_12111154 0.66 ENSDART00000036779
transmembrane protein 178B
chr4_-_908821 0.66 ENSDART00000168266
melanocortin 2 receptor accessory protein 2b
chr25_-_4733008 0.65 ENSDART00000191884
dopamine receptor D4a
chr21_-_20765338 0.64 ENSDART00000135940
growth hormone receptor b
chr9_-_2945008 0.63 ENSDART00000183452
sterile alpha motif and leucine zipper containing kinase AZK
chr1_+_55264712 0.62 ENSDART00000193162

chr18_+_19006063 0.60 ENSDART00000135729
solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
chr9_+_1313418 0.59 ENSDART00000191361
caspase 8, apoptosis-related cysteine peptidase, like 2
chr19_+_34169055 0.58 ENSDART00000135592
ENSDART00000186043
POC1 centriolar protein homolog B (Chlamydomonas), like
chr25_+_35891342 0.58 ENSDART00000147093
LSM14A mRNA processing body assembly factor a
chr5_-_40910749 0.58 ENSDART00000083467
ENSDART00000133183
poly (ADP-ribose) polymerase family, member 8
chr2_-_37537887 0.57 ENSDART00000143496
ENSDART00000025841
rho/rac guanine nucleotide exchange factor (GEF) 18a
chr13_+_12528043 0.56 ENSDART00000057761
retinal pigment epithelium-derived rhodopsin homolog
chr23_-_42810664 0.56 ENSDART00000102328
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2a
chr19_-_35340027 0.56 ENSDART00000146394
microtubule-actin crosslinking factor 1a
chr15_-_26931541 0.55 ENSDART00000027563
coiled-coil domain containing 9
chr2_-_32551178 0.55 ENSDART00000145603
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3a
chr10_+_39476600 0.54 ENSDART00000135756
kirre like nephrin family adhesion molecule 3a
chr13_+_1015749 0.53 ENSDART00000190982
prokineticin receptor 1b
chr13_-_8815530 0.53 ENSDART00000122498
si:ch73-105b23.6
chr4_+_28442223 0.53 ENSDART00000150879
zinc finger protein 1067
chr17_+_10593398 0.52 ENSDART00000168897
ENSDART00000193989
ENSDART00000191664
ENSDART00000167188
mitogen-activated protein kinase binding protein 1
chr21_+_45496442 0.51 ENSDART00000164880
si:dkey-223p19.1
chr21_+_36581384 0.51 ENSDART00000183924

chr3_+_23063718 0.50 ENSDART00000140225
ENSDART00000184431
beta-1,4-N-acetyl-galactosaminyl transferase 2, tandem duplicate 1
chr12_-_33659328 0.49 ENSDART00000153457
transmembrane protein 94
chr7_+_22330466 0.49 ENSDART00000187347
ENSDART00000174483
fibroblast growth factor 11a
chr10_+_39476432 0.48 ENSDART00000190375
ENSDART00000183954
kirre like nephrin family adhesion molecule 3a
chr10_-_40968095 0.47 ENSDART00000184104
neuropeptide FF receptor 1 like 1
chr18_-_6975175 0.47 ENSDART00000134194
si:dkey-266m15.6
chr16_+_54592907 0.46 ENSDART00000172113
DENN/MADD domain containing 4B
chr8_+_4838114 0.45 ENSDART00000146667
es1 protein
chr7_+_20030888 0.45 ENSDART00000192808
solute carrier family 16, member 13 (monocarboxylic acid transporter 13)
chr20_-_30920356 0.44 ENSDART00000022951
kinesin family member 25
chr23_+_16935494 0.43 ENSDART00000143120
si:dkey-147f3.4
chr24_-_21689146 0.43 ENSDART00000105917
ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase
chr14_+_52413846 0.43 ENSDART00000160952
nitric oxide associated 1
chr7_+_39011852 0.41 ENSDART00000093009
diacylglycerol kinase, zeta a
chr10_-_322769 0.40 ENSDART00000165244
v-akt murine thymoma viral oncogene homolog 2, like
chr4_-_49133107 0.39 ENSDART00000150806
zinc finger protein 1146
chr20_+_53577502 0.39 ENSDART00000126983
myosin, heavy chain 6, cardiac muscle, alpha
chr25_+_35913614 0.39 ENSDART00000022437
glucose-6-phosphate isomerase a
chr18_+_27439680 0.38 ENSDART00000014726
tumor protein p53 inducible protein 11b
chr11_+_19080400 0.38 ENSDART00000044423
membrane associated guanylate kinase, WW and PDZ domain containing 1b
chr5_-_23715027 0.37 ENSDART00000139020
globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 1
chr9_-_394088 0.37 ENSDART00000169014
si:dkey-11f4.7
chr9_+_7030016 0.36 ENSDART00000148047
ENSDART00000148181
inositol polyphosphate-4-phosphatase type I Aa
chr15_-_34468599 0.35 ENSDART00000192984
mesenchyme homeobox 2a
chr11_-_15090118 0.35 ENSDART00000171118
solute carrier family 1 (glutamate transporter), member 8a
chr20_-_35012093 0.35 ENSDART00000062761
consortin, connexin sorting protein b
chr14_+_30340251 0.34 ENSDART00000148448
microtubule associated tumor suppressor 1a
chr15_+_25683069 0.33 ENSDART00000148190
hypermethylated in cancer 1
chr23_-_437467 0.33 ENSDART00000192106
tetraspanin 2b
chr10_+_6013076 0.32 ENSDART00000167613
ENSDART00000159216
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr9_+_1365747 0.31 ENSDART00000140917
ENSDART00000036605
protein kinase, interferon-inducible double stranded RNA dependent activator
chr6_-_39218609 0.28 ENSDART00000133305
osteosarcoma amplified 9, endoplasmic reticulum lectin
chr23_-_35064785 0.28 ENSDART00000172240

chr20_+_54666222 0.27 ENSDART00000166592

chr15_+_887032 0.27 ENSDART00000156395
si:dkey-7i4.9
chr21_-_38853737 0.25 ENSDART00000184100
toll-like receptor 22
chr4_+_50401133 0.25 ENSDART00000150644
si:dkey-156k2.7
chr5_-_27994679 0.24 ENSDART00000132740
protein phosphatase 3, catalytic subunit, gamma isozyme, a
chr2_+_30721466 0.24 ENSDART00000128982
si:dkey-94e7.2
chr19_+_43884120 0.23 ENSDART00000139684
ENSDART00000142312
lysophospholipase II
chr15_+_20355465 0.23 ENSDART00000143092
ENSDART00000062666
interleukin 15, like
chr4_-_73561848 0.22 ENSDART00000174210

chr1_+_52633367 0.21 ENSDART00000134658
solute carrier family 44 (choline transporter), member 1a
chr4_+_22480169 0.20 ENSDART00000146272
ENSDART00000066904
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2
chr7_+_39011355 0.20 ENSDART00000173855
diacylglycerol kinase, zeta a
chr24_+_10039165 0.20 ENSDART00000144186
POU class 6 homeobox 2
chr7_+_13702248 0.19 ENSDART00000172811
programmed cell death 7
chr7_-_54320088 0.18 ENSDART00000172396
Fas (tnfrsf6)-associated via death domain
chr25_+_16731802 0.18 ENSDART00000188715

chr3_-_20058417 0.17 ENSDART00000165695
upstream binding transcription factor, RNA polymerase I
chr20_-_2134620 0.17 ENSDART00000064375
transmembrane protein 244
chr23_-_45501177 0.15 ENSDART00000150103
collagen type XXIV alpha 1
chr4_+_11053301 0.15 ENSDART00000140362
coiled-coil domain containing 59
chr13_-_29406534 0.14 ENSDART00000100877
zgc:153142
chr14_-_36412473 0.12 ENSDART00000128244
ENSDART00000138376
ankyrin repeat and SOCS box containing 5a
chr13_+_30228077 0.12 ENSDART00000100813
ENSDART00000147729
ENSDART00000133404
ribosomal protein S24
chr17_+_14886828 0.11 ENSDART00000010507
ENSDART00000131052
prostaglandin E receptor 2a (subtype EP2)
chr16_+_53519048 0.10 ENSDART00000124691
sphingomyelin phosphodiesterase 5
chr10_+_8690936 0.09 ENSDART00000144218
si:dkey-27b3.4
chr18_-_24989580 0.07 ENSDART00000163449
chromodomain helicase DNA binding protein 2
chr9_-_3519253 0.06 ENSDART00000169586
ddb1 and cul4 associated factor 17
chr2_+_24080694 0.05 ENSDART00000024058
potassium voltage-gated channel, subfamily H (eag-related), member 2a

Network of associatons between targets according to the STRING database.

First level regulatory network of crx+otx1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0030186 melatonin metabolic process(GO:0030186)
0.5 2.5 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.4 1.5 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.3 1.4 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.3 1.3 GO:0050996 positive regulation of lipid catabolic process(GO:0050996)
0.3 1.0 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.2 0.7 GO:0042941 D-amino acid transport(GO:0042940) D-alanine transport(GO:0042941) D-serine transport(GO:0042942)
0.2 3.8 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.2 2.5 GO:1902042 regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902041) negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
0.2 1.7 GO:0043584 nose development(GO:0043584)
0.2 0.6 GO:0060292 long term synaptic depression(GO:0060292)
0.2 1.4 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.2 0.7 GO:0090299 regulation of neural crest formation(GO:0090299)
0.2 1.9 GO:0045667 regulation of osteoblast differentiation(GO:0045667)
0.1 0.4 GO:0046415 urate catabolic process(GO:0019628) urate metabolic process(GO:0046415)
0.1 2.3 GO:0046549 retinal cone cell development(GO:0046549)
0.1 1.6 GO:0006611 protein export from nucleus(GO:0006611)
0.1 3.1 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.1 0.5 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1 2.2 GO:0006584 catecholamine metabolic process(GO:0006584) catechol-containing compound metabolic process(GO:0009712)
0.1 1.2 GO:0046548 retinal rod cell development(GO:0046548)
0.1 0.3 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.1 0.3 GO:0010142 farnesyl diphosphate biosynthetic process, mevalonate pathway(GO:0010142) isoprenoid biosynthetic process via mevalonate(GO:1902767)
0.1 4.7 GO:0061512 protein localization to cilium(GO:0061512)
0.1 0.6 GO:0060832 oocyte animal/vegetal axis specification(GO:0060832)
0.1 0.9 GO:0036368 cone photoresponse recovery(GO:0036368)
0.1 1.2 GO:0040033 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.1 2.5 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.1 0.6 GO:0034063 stress granule assembly(GO:0034063)
0.1 0.9 GO:0006336 DNA replication-independent nucleosome assembly(GO:0006336)
0.1 1.4 GO:0002574 thrombocyte differentiation(GO:0002574)
0.1 0.4 GO:0055014 atrial cardiac muscle cell development(GO:0055014)
0.1 0.5 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.1 0.5 GO:0006337 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.1 0.7 GO:0097009 energy homeostasis(GO:0097009)
0.1 4.9 GO:0030042 actin filament depolymerization(GO:0030042)
0.1 1.1 GO:0032438 melanosome organization(GO:0032438)
0.1 1.9 GO:0055008 cardiac muscle tissue morphogenesis(GO:0055008)
0.1 0.3 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.1 0.9 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.1 0.6 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) response to growth hormone(GO:0060416) cellular response to growth hormone stimulus(GO:0071378)
0.1 0.5 GO:0030431 sleep(GO:0030431)
0.1 0.7 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 1.6 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 0.7 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.2 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.0 0.3 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.0 1.9 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 0.4 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.0 1.7 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.3 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.6 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.5 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.8 GO:0097194 execution phase of apoptosis(GO:0097194)
0.0 2.1 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 0.5 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.6 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.1 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.0 1.4 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.1 GO:0034695 response to prostaglandin E(GO:0034695) cellular response to prostaglandin E stimulus(GO:0071380)
0.0 1.2 GO:0006081 cellular aldehyde metabolic process(GO:0006081)
0.0 0.2 GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.0 1.8 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.4 GO:0051156 glucose 6-phosphate metabolic process(GO:0051156)
0.0 0.4 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.2 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.0 0.7 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 2.1 GO:0051260 protein homooligomerization(GO:0051260)
0.0 0.6 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.6 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.8 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.0 GO:0070257 regulation of mucus secretion(GO:0070255) positive regulation of mucus secretion(GO:0070257)
0.0 1.5 GO:0030239 myofibril assembly(GO:0030239)
0.0 0.8 GO:0007416 synapse assembly(GO:0007416)
0.0 0.2 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.9 GO:0031258 lamellipodium membrane(GO:0031258)
0.2 0.6 GO:0070195 growth hormone receptor complex(GO:0070195)
0.1 1.4 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 3.2 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 2.5 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 0.9 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 1.9 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 1.9 GO:0031430 M band(GO:0031430)
0.1 1.1 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 0.6 GO:0032019 mitochondrial cloud(GO:0032019)
0.0 0.1 GO:0005592 collagen type XI trimer(GO:0005592)
0.0 2.2 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 2.1 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.6 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.5 GO:0071564 npBAF complex(GO:0071564)
0.0 2.3 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 1.1 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 2.1 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 2.1 GO:0005871 kinesin complex(GO:0005871)
0.0 1.4 GO:0005776 autophagosome(GO:0005776)
0.0 0.9 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 1.7 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 2.1 GO:0014069 postsynaptic density(GO:0014069)
0.0 0.2 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.8 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0038046 enkephalin receptor activity(GO:0038046)
0.5 1.4 GO:0055105 ubiquitin-protein transferase inhibitor activity(GO:0055105)
0.4 1.3 GO:0005131 growth hormone receptor binding(GO:0005131) growth hormone activity(GO:0070186)
0.2 2.2 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.2 3.1 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.2 1.4 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.2 0.5 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.2 0.7 GO:0031782 type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.2 0.6 GO:0004903 growth hormone receptor activity(GO:0004903)
0.2 2.0 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 2.0 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 0.9 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1 3.2 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 1.2 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.1 0.8 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.1 0.3 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.1 1.3 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.1 0.7 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 0.3 GO:0071253 connexin binding(GO:0071253)
0.1 2.5 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 1.7 GO:0019840 retinoid binding(GO:0005501) isoprenoid binding(GO:0019840)
0.1 0.6 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.1 0.4 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.0 0.7 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.7 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 0.7 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.6 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 1.1 GO:0015248 sterol transporter activity(GO:0015248)
0.0 2.5 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 1.9 GO:0071949 FAD binding(GO:0071949)
0.0 1.9 GO:0005178 integrin binding(GO:0005178)
0.0 0.4 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 2.3 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.6 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.8 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.6 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 1.0 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.9 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 2.1 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.5 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.7 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.9 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.5 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.0 2.7 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.0 5.5 GO:0051015 actin filament binding(GO:0051015)
0.0 2.1 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 0.2 GO:0002020 protease binding(GO:0002020)
0.0 0.8 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.6 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.4 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.2 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.6 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.1 GO:0004957 prostaglandin E receptor activity(GO:0004957)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.7 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.9 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.6 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.3 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.5 PID CERAMIDE PATHWAY Ceramide signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.5 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 2.5 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 1.9 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 1.3 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 0.6 REACTOME OPSINS Genes involved in Opsins
0.1 1.0 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.1 1.7 REACTOME KINESINS Genes involved in Kinesins
0.1 1.3 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 0.7 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 2.1 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 0.8 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.1 1.3 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.2 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.7 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.4 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.2 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.3 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis