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avrg: GSE58827: Dynamics of the Mouse Liver
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Results for Tbp
Z-value: 2.41
Motif logo
Transcription factors associated with Tbp
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
Tbp
|
ENSMUSG00000014767.10 | TATA box binding protein |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Tbp | mm10_v2_chr17_+_15499888_15499960 | 0.50 | 1.8e-03 | Click! |
Activity profile of Tbp motif
Sorted Z-values of Tbp motif
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr16_-_36455378 | 41.31 |
ENSMUST00000068182.2
|
Stfa3
|
stefin A3 |
| chr16_-_36367623 | 38.93 |
ENSMUST00000096089.2
|
BC100530
|
cDNA sequence BC100530 |
| chr16_+_36184082 | 33.68 |
ENSMUST00000114858.1
|
Gm5483
|
predicted gene 5483 |
| chr16_+_36156801 | 32.28 |
ENSMUST00000079184.4
|
Stfa2l1
|
stefin A2 like 1 |
| chr16_+_36277145 | 30.44 |
ENSMUST00000042097.9
|
Stfa1
|
stefin A1 |
| chr14_+_80000292 | 28.31 |
ENSMUST00000088735.3
|
Olfm4
|
olfactomedin 4 |
| chr9_+_98490522 | 26.57 |
ENSMUST00000035029.2
|
Rbp2
|
retinol binding protein 2, cellular |
| chr11_+_87793470 | 26.45 |
ENSMUST00000020779.4
|
Mpo
|
myeloperoxidase |
| chr6_-_41314700 | 25.87 |
ENSMUST00000064324.5
|
Try5
|
trypsin 5 |
| chr3_-_106167564 | 25.61 |
ENSMUST00000063062.8
|
Chi3l3
|
chitinase 3-like 3 |
| chr3_-_90695706 | 24.84 |
ENSMUST00000069960.5
ENSMUST00000117167.1 |
S100a9
|
S100 calcium binding protein A9 (calgranulin B) |
| chr16_+_36210403 | 24.43 |
ENSMUST00000089628.3
|
Gm5416
|
predicted gene 5416 |
| chr6_-_41377604 | 22.86 |
ENSMUST00000096003.5
|
Prss3
|
protease, serine, 3 |
| chr3_-_106149761 | 21.62 |
ENSMUST00000149836.1
|
Chi3l3
|
chitinase 3-like 3 |
| chr14_-_56102458 | 20.61 |
ENSMUST00000015583.1
|
Ctsg
|
cathepsin G |
| chr6_+_142298419 | 19.94 |
ENSMUST00000041993.2
|
Iapp
|
islet amyloid polypeptide |
| chr11_-_55185029 | 19.92 |
ENSMUST00000039305.5
|
Slc36a2
|
solute carrier family 36 (proton/amino acid symporter), member 2 |
| chr11_-_99438143 | 19.61 |
ENSMUST00000017743.2
|
Krt20
|
keratin 20 |
| chr9_-_67832325 | 17.67 |
ENSMUST00000054500.5
|
C2cd4a
|
C2 calcium-dependent domain containing 4A |
| chr7_-_103853199 | 17.50 |
ENSMUST00000033229.3
|
Hbb-y
|
hemoglobin Y, beta-like embryonic chain |
| chr3_-_20275659 | 16.48 |
ENSMUST00000011607.5
|
Cpb1
|
carboxypeptidase B1 (tissue) |
| chr1_+_134182404 | 15.57 |
ENSMUST00000153856.1
ENSMUST00000082060.3 ENSMUST00000133701.1 ENSMUST00000132873.1 |
Chi3l1
|
chitinase 3-like 1 |
| chr1_+_134182150 | 15.31 |
ENSMUST00000156873.1
|
Chi3l1
|
chitinase 3-like 1 |
| chr6_+_41354105 | 15.31 |
ENSMUST00000072103.5
|
Try10
|
trypsin 10 |
| chr13_+_21717626 | 15.16 |
ENSMUST00000091754.2
|
Hist1h3h
|
histone cluster 1, H3h |
| chr11_-_102107822 | 14.08 |
ENSMUST00000177304.1
ENSMUST00000017455.8 |
Pyy
|
peptide YY |
| chr7_-_103843154 | 14.02 |
ENSMUST00000063957.4
|
Hbb-bh1
|
hemoglobin Z, beta-like embryonic chain |
| chr4_+_34893772 | 13.93 |
ENSMUST00000029975.3
ENSMUST00000135871.1 ENSMUST00000108130.1 |
Cga
|
glycoprotein hormones, alpha subunit |
| chr4_+_120666562 | 13.91 |
ENSMUST00000094814.4
|
Cited4
|
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4 |
| chr7_-_103813913 | 13.20 |
ENSMUST00000098192.3
|
Hbb-bt
|
hemoglobin, beta adult t chain |
| chr6_-_41035501 | 13.15 |
ENSMUST00000031931.5
|
2210010C04Rik
|
RIKEN cDNA 2210010C04 gene |
| chr14_+_56042123 | 12.91 |
ENSMUST00000015576.4
|
Mcpt2
|
mast cell protease 2 |
| chr6_+_41392356 | 12.76 |
ENSMUST00000049079.7
|
Gm5771
|
predicted gene 5771 |
| chr8_+_94179089 | 12.74 |
ENSMUST00000034215.6
|
Mt1
|
metallothionein 1 |
| chr18_-_78123324 | 12.63 |
ENSMUST00000160292.1
ENSMUST00000091813.5 |
Slc14a1
|
solute carrier family 14 (urea transporter), member 1 |
| chr2_-_114052804 | 12.40 |
ENSMUST00000090269.6
|
Actc1
|
actin, alpha, cardiac muscle 1 |
| chr6_-_67535783 | 12.36 |
ENSMUST00000058178.4
|
Tacstd2
|
tumor-associated calcium signal transducer 2 |
| chr3_+_103832562 | 12.18 |
ENSMUST00000062945.5
|
Bcl2l15
|
BCLl2-like 15 |
| chr11_+_67277124 | 12.16 |
ENSMUST00000019625.5
|
Myh8
|
myosin, heavy polypeptide 8, skeletal muscle, perinatal |
| chr2_-_62483637 | 12.16 |
ENSMUST00000136686.1
ENSMUST00000102733.3 |
Gcg
|
glucagon |
| chr3_-_20242173 | 12.12 |
ENSMUST00000001921.1
|
Cpa3
|
carboxypeptidase A3, mast cell |
| chr7_-_45526146 | 11.83 |
ENSMUST00000167273.1
ENSMUST00000042105.8 |
Ppp1r15a
|
protein phosphatase 1, regulatory (inhibitor) subunit 15A |
| chr7_-_103827922 | 11.62 |
ENSMUST00000023934.6
ENSMUST00000153218.1 |
Hbb-bs
|
hemoglobin, beta adult s chain |
| chr17_-_31129602 | 11.36 |
ENSMUST00000024827.4
|
Tff3
|
trefoil factor 3, intestinal |
| chr10_+_43579161 | 10.97 |
ENSMUST00000058714.8
|
Cd24a
|
CD24a antigen |
| chr11_-_69948145 | 10.94 |
ENSMUST00000179298.1
ENSMUST00000018710.6 ENSMUST00000135437.1 ENSMUST00000141837.2 ENSMUST00000142500.1 |
Slc2a4
|
solute carrier family 2 (facilitated glucose transporter), member 4 |
| chr6_+_4747306 | 10.46 |
ENSMUST00000175823.1
ENSMUST00000176204.1 ENSMUST00000166678.1 |
Peg10
|
paternally expressed 10 |
| chr7_-_143502515 | 10.34 |
ENSMUST00000010904.4
|
Phlda2
|
pleckstrin homology-like domain, family A, member 2 |
| chr15_-_101491509 | 10.13 |
ENSMUST00000023718.7
|
5430421N21Rik
|
RIKEN cDNA 5430421N21 gene |
| chr7_-_44532064 | 9.94 |
ENSMUST00000098483.2
ENSMUST00000035323.4 |
Spib
|
Spi-B transcription factor (Spi-1/PU.1 related) |
| chr11_-_99024179 | 9.93 |
ENSMUST00000068031.7
|
Top2a
|
topoisomerase (DNA) II alpha |
| chr11_+_76998595 | 9.84 |
ENSMUST00000108402.2
ENSMUST00000021195.4 |
Slc6a4
|
solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 |
| chr13_-_21780616 | 9.83 |
ENSMUST00000080511.2
|
Hist1h1b
|
histone cluster 1, H1b |
| chr11_-_102897123 | 9.82 |
ENSMUST00000067444.3
|
Gfap
|
glial fibrillary acidic protein |
| chr4_-_41098174 | 9.77 |
ENSMUST00000055327.7
|
Aqp3
|
aquaporin 3 |
| chr11_-_120551126 | 9.76 |
ENSMUST00000026121.2
|
Ppp1r27
|
protein phosphatase 1, regulatory subunit 27 |
| chr11_+_120949053 | 9.60 |
ENSMUST00000154187.1
ENSMUST00000100130.3 ENSMUST00000129473.1 ENSMUST00000168579.1 |
Slc16a3
|
solute carrier family 16 (monocarboxylic acid transporters), member 3 |
| chr13_-_73700721 | 9.11 |
ENSMUST00000022048.5
|
Slc6a19
|
solute carrier family 6 (neurotransmitter transporter), member 19 |
| chr2_-_164356067 | 9.06 |
ENSMUST00000165980.1
|
Slpi
|
secretory leukocyte peptidase inhibitor |
| chr8_-_105933832 | 9.03 |
ENSMUST00000034368.6
|
Ctrl
|
chymotrypsin-like |
| chr13_+_23763660 | 8.88 |
ENSMUST00000055770.1
|
Hist1h1a
|
histone cluster 1, H1a |
| chr11_-_100121558 | 8.77 |
ENSMUST00000007275.2
|
Krt13
|
keratin 13 |
| chr6_-_87981482 | 8.75 |
ENSMUST00000056403.5
|
H1fx
|
H1 histone family, member X |
| chr2_-_164356507 | 8.67 |
ENSMUST00000109367.3
|
Slpi
|
secretory leukocyte peptidase inhibitor |
| chr11_-_102897146 | 8.55 |
ENSMUST00000077902.4
|
Gfap
|
glial fibrillary acidic protein |
| chr4_-_119658781 | 8.54 |
ENSMUST00000106309.2
ENSMUST00000044426.7 |
Guca2b
|
guanylate cyclase activator 2b (retina) |
| chr10_-_88605017 | 8.52 |
ENSMUST00000119185.1
ENSMUST00000121629.1 |
Mybpc1
|
myosin binding protein C, slow-type |
| chr19_-_3414464 | 8.49 |
ENSMUST00000025842.6
|
Gal
|
galanin |
| chr7_-_4812351 | 8.46 |
ENSMUST00000079496.7
|
Ube2s
|
ubiquitin-conjugating enzyme E2S |
| chr14_-_56062307 | 8.35 |
ENSMUST00000043249.8
|
Mcpt4
|
mast cell protease 4 |
| chr8_+_84969824 | 8.28 |
ENSMUST00000125893.1
|
Prdx2
|
peroxiredoxin 2 |
| chr2_+_119618717 | 8.23 |
ENSMUST00000028771.7
|
Nusap1
|
nucleolar and spindle associated protein 1 |
| chr4_+_123282778 | 8.16 |
ENSMUST00000106243.1
ENSMUST00000106241.1 ENSMUST00000080178.6 |
Pabpc4
|
poly(A) binding protein, cytoplasmic 4 |
| chr18_+_34625009 | 7.96 |
ENSMUST00000166044.1
|
Kif20a
|
kinesin family member 20A |
| chr8_+_84969767 | 7.85 |
ENSMUST00000109733.1
|
Prdx2
|
peroxiredoxin 2 |
| chr13_+_23575753 | 7.80 |
ENSMUST00000105105.1
|
Hist1h3d
|
histone cluster 1, H3d |
| chr19_+_60755947 | 7.74 |
ENSMUST00000088237.4
|
Nanos1
|
nanos homolog 1 (Drosophila) |
| chr6_+_78425973 | 7.70 |
ENSMUST00000079926.5
|
Reg1
|
regenerating islet-derived 1 |
| chr18_+_34624621 | 7.45 |
ENSMUST00000167161.1
|
Kif20a
|
kinesin family member 20A |
| chr11_-_100135928 | 7.33 |
ENSMUST00000107411.2
|
Krt15
|
keratin 15 |
| chr8_+_84969587 | 7.24 |
ENSMUST00000109734.1
ENSMUST00000005292.8 |
Prdx2
|
peroxiredoxin 2 |
| chr6_+_78370877 | 7.19 |
ENSMUST00000096904.3
|
Reg3b
|
regenerating islet-derived 3 beta |
| chr15_+_79895017 | 7.10 |
ENSMUST00000023054.7
|
Apobec3
|
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3 |
| chr7_+_131032061 | 6.90 |
ENSMUST00000084509.3
|
Dmbt1
|
deleted in malignant brain tumors 1 |
| chr7_-_16259185 | 6.84 |
ENSMUST00000168818.1
|
C5ar1
|
complement component 5a receptor 1 |
| chr13_-_23745511 | 6.69 |
ENSMUST00000091752.2
|
Hist1h3c
|
histone cluster 1, H3c |
| chr15_-_101712891 | 6.65 |
ENSMUST00000023709.5
|
Krt5
|
keratin 5 |
| chr13_+_23544052 | 6.61 |
ENSMUST00000075558.2
|
Hist1h3f
|
histone cluster 1, H3f |
| chr4_-_140810646 | 6.61 |
ENSMUST00000026377.2
|
Padi3
|
peptidyl arginine deiminase, type III |
| chr10_+_88091070 | 6.59 |
ENSMUST00000048621.7
|
Pmch
|
pro-melanin-concentrating hormone |
| chr18_+_36528145 | 6.47 |
ENSMUST00000074298.6
ENSMUST00000115694.2 |
Slc4a9
|
solute carrier family 4, sodium bicarbonate cotransporter, member 9 |
| chr7_-_141655319 | 6.25 |
ENSMUST00000062451.7
|
Muc6
|
mucin 6, gastric |
| chr2_-_119618455 | 6.23 |
ENSMUST00000123818.1
|
Oip5
|
Opa interacting protein 5 |
| chr6_-_78378851 | 6.16 |
ENSMUST00000089667.1
ENSMUST00000167492.1 |
Reg3d
|
regenerating islet-derived 3 delta |
| chr19_-_34255325 | 5.91 |
ENSMUST00000039631.8
|
Acta2
|
actin, alpha 2, smooth muscle, aorta |
| chr4_-_42853888 | 5.91 |
ENSMUST00000107979.1
|
Gm12429
|
predicted gene 12429 |
| chr15_-_101694299 | 5.85 |
ENSMUST00000023788.6
|
Krt6a
|
keratin 6A |
| chr10_+_79777261 | 5.84 |
ENSMUST00000020575.4
|
Fstl3
|
follistatin-like 3 |
| chr17_-_24251382 | 5.78 |
ENSMUST00000115390.3
|
Ccnf
|
cyclin F |
| chr1_-_134079114 | 5.73 |
ENSMUST00000020692.6
|
Btg2
|
B cell translocation gene 2, anti-proliferative |
| chr13_+_23752267 | 5.72 |
ENSMUST00000091703.2
|
Hist1h3b
|
histone cluster 1, H3b |
| chr7_-_109781538 | 5.52 |
ENSMUST00000033331.6
|
Nrip3
|
nuclear receptor interacting protein 3 |
| chr3_-_92458715 | 5.47 |
ENSMUST00000058142.3
|
Sprr3
|
small proline-rich protein 3 |
| chr8_+_15057646 | 5.43 |
ENSMUST00000033842.3
|
Myom2
|
myomesin 2 |
| chr3_-_106219477 | 5.40 |
ENSMUST00000082219.5
|
Chi3l4
|
chitinase 3-like 4 |
| chr6_-_72958097 | 5.38 |
ENSMUST00000114049.1
|
Tmsb10
|
thymosin, beta 10 |
| chr11_-_115514374 | 5.32 |
ENSMUST00000021083.6
|
Hn1
|
hematological and neurological expressed sequence 1 |
| chr15_-_98482683 | 5.31 |
ENSMUST00000023726.3
|
Lalba
|
lactalbumin, alpha |
| chr13_-_23762378 | 5.25 |
ENSMUST00000091701.2
|
Hist1h3a
|
histone cluster 1, H3a |
| chrX_+_164438039 | 5.22 |
ENSMUST00000033755.5
|
Asb11
|
ankyrin repeat and SOCS box-containing 11 |
| chr6_-_125494754 | 5.20 |
ENSMUST00000032492.8
|
Cd9
|
CD9 antigen |
| chr7_-_30612731 | 5.18 |
ENSMUST00000006476.4
|
Upk1a
|
uroplakin 1A |
| chr9_+_121777607 | 5.12 |
ENSMUST00000098272.2
|
Klhl40
|
kelch-like 40 |
| chr5_-_114823460 | 5.05 |
ENSMUST00000140374.1
ENSMUST00000100850.4 |
Gm20499
2610524H06Rik
|
predicted gene 20499 RIKEN cDNA 2610524H06 gene |
| chr11_-_100261021 | 5.04 |
ENSMUST00000080893.6
|
Krt17
|
keratin 17 |
| chr6_-_113719880 | 5.03 |
ENSMUST00000064993.5
|
Ghrl
|
ghrelin |
| chrX_+_164140447 | 5.02 |
ENSMUST00000073973.4
|
Ace2
|
angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 |
| chr2_+_13573927 | 5.00 |
ENSMUST00000141365.1
ENSMUST00000028062.2 |
Vim
|
vimentin |
| chr4_-_132353605 | 4.96 |
ENSMUST00000155129.1
|
Rcc1
|
regulator of chromosome condensation 1 |
| chrX_+_73774397 | 4.93 |
ENSMUST00000002081.5
|
Srpk3
|
serine/arginine-rich protein specific kinase 3 |
| chr13_-_21783391 | 4.90 |
ENSMUST00000099704.3
|
Hist1h3i
|
histone cluster 1, H3i |
| chr11_+_82101836 | 4.77 |
ENSMUST00000000194.3
|
Ccl12
|
chemokine (C-C motif) ligand 12 |
| chr8_-_13254154 | 4.72 |
ENSMUST00000033825.4
|
Adprhl1
|
ADP-ribosylhydrolase like 1 |
| chr17_-_33824346 | 4.71 |
ENSMUST00000173879.1
ENSMUST00000166693.2 ENSMUST00000173019.1 ENSMUST00000087342.6 ENSMUST00000173844.1 |
Rps28
|
ribosomal protein S28 |
| chr12_+_81631369 | 4.61 |
ENSMUST00000036116.5
|
Ttc9
|
tetratricopeptide repeat domain 9 |
| chr13_+_21716385 | 4.59 |
ENSMUST00000070124.3
|
Hist1h2ai
|
histone cluster 1, H2ai |
| chr10_-_93589621 | 4.55 |
ENSMUST00000020203.6
|
Snrpf
|
small nuclear ribonucleoprotein polypeptide F |
| chr6_-_72958465 | 4.51 |
ENSMUST00000114050.1
|
Tmsb10
|
thymosin, beta 10 |
| chr5_-_99978914 | 4.38 |
ENSMUST00000112939.3
ENSMUST00000171786.1 ENSMUST00000072750.6 ENSMUST00000019128.8 ENSMUST00000172361.1 |
Hnrnpd
|
heterogeneous nuclear ribonucleoprotein D |
| chr17_-_33955658 | 4.26 |
ENSMUST00000174609.2
ENSMUST00000008812.7 |
Rps18
|
ribosomal protein S18 |
| chr6_+_48895243 | 4.24 |
ENSMUST00000031835.7
|
Aoc1
|
amine oxidase, copper-containing 1 |
| chr13_-_23683941 | 4.23 |
ENSMUST00000171127.1
|
Hist1h2ac
|
histone cluster 1, H2ac |
| chr17_+_23726336 | 4.21 |
ENSMUST00000024701.7
|
Pkmyt1
|
protein kinase, membrane associated tyrosine/threonine 1 |
| chr4_-_133967296 | 4.20 |
ENSMUST00000105893.1
|
Hmgn2
|
high mobility group nucleosomal binding domain 2 |
| chr15_-_80083374 | 4.17 |
ENSMUST00000081650.7
|
Rpl3
|
ribosomal protein L3 |
| chr5_+_76809964 | 4.12 |
ENSMUST00000120818.1
|
C530008M17Rik
|
RIKEN cDNA C530008M17 gene |
| chr11_+_3289880 | 4.06 |
ENSMUST00000110043.1
ENSMUST00000094471.3 |
Patz1
|
POZ (BTB) and AT hook containing zinc finger 1 |
| chr11_-_33163072 | 4.04 |
ENSMUST00000093201.6
ENSMUST00000101375.4 ENSMUST00000109354.3 ENSMUST00000075641.3 |
Npm1
|
nucleophosmin 1 |
| chr13_-_21787218 | 3.97 |
ENSMUST00000091751.2
|
Hist1h2an
|
histone cluster 1, H2an |
| chr9_-_95815389 | 3.97 |
ENSMUST00000119760.1
|
Pls1
|
plastin 1 (I-isoform) |
| chr15_-_101850778 | 3.89 |
ENSMUST00000023790.3
|
Krt1
|
keratin 1 |
| chr19_+_55180799 | 3.88 |
ENSMUST00000025936.5
|
Tectb
|
tectorin beta |
| chr16_-_36131156 | 3.88 |
ENSMUST00000161638.1
ENSMUST00000096090.2 |
Csta
|
cystatin A |
| chr13_+_23581563 | 3.87 |
ENSMUST00000102968.1
|
Hist1h4d
|
histone cluster 1, H4d |
| chr11_-_57832142 | 3.77 |
ENSMUST00000036917.2
|
Hand1
|
heart and neural crest derivatives expressed transcript 1 |
| chr6_-_112696604 | 3.77 |
ENSMUST00000113182.1
ENSMUST00000113180.1 ENSMUST00000068487.5 ENSMUST00000077088.4 |
Rad18
|
RAD18 homolog (S. cerevisiae) |
| chr13_-_23622502 | 3.65 |
ENSMUST00000062045.2
|
Hist1h1e
|
histone cluster 1, H1e |
| chr11_+_94936224 | 3.61 |
ENSMUST00000001547.7
|
Col1a1
|
collagen, type I, alpha 1 |
| chr15_-_101680281 | 3.60 |
ENSMUST00000023786.5
|
Krt6b
|
keratin 6B |
| chr4_+_127021311 | 3.49 |
ENSMUST00000030623.7
|
Sfpq
|
splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated) |
| chr3_-_92485886 | 3.45 |
ENSMUST00000054599.7
|
Sprr1a
|
small proline-rich protein 1A |
| chr2_+_167062934 | 3.41 |
ENSMUST00000125674.1
|
1500012F01Rik
|
RIKEN cDNA 1500012F01 gene |
| chr6_-_87672142 | 3.19 |
ENSMUST00000032130.2
ENSMUST00000065997.2 |
Aplf
|
aprataxin and PNKP like factor |
| chr9_+_95637601 | 3.17 |
ENSMUST00000015498.8
|
Pcolce2
|
procollagen C-endopeptidase enhancer 2 |
| chr19_-_4283033 | 3.14 |
ENSMUST00000167215.1
ENSMUST00000056888.6 |
Ankrd13d
|
ankyrin repeat domain 13 family, member D |
| chr9_+_108508005 | 3.11 |
ENSMUST00000006838.8
ENSMUST00000134939.1 |
Qars
|
glutaminyl-tRNA synthetase |
| chr14_+_56017964 | 2.95 |
ENSMUST00000022836.4
|
Mcpt1
|
mast cell protease 1 |
| chr1_+_63176818 | 2.95 |
ENSMUST00000129339.1
|
Eef1b2
|
eukaryotic translation elongation factor 1 beta 2 |
| chr4_-_116627478 | 2.93 |
ENSMUST00000081182.4
ENSMUST00000030457.5 |
Nasp
|
nuclear autoantigenic sperm protein (histone-binding) |
| chr9_+_30942541 | 2.93 |
ENSMUST00000068135.6
|
Adamts8
|
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 8 |
| chr13_-_113663670 | 2.93 |
ENSMUST00000054650.4
|
Hspb3
|
heat shock protein 3 |
| chr8_+_94137197 | 2.88 |
ENSMUST00000034207.6
|
Mt4
|
metallothionein 4 |
| chr19_-_53589067 | 2.86 |
ENSMUST00000095978.3
|
Nutf2-ps1
|
nuclear transport factor 2, pseudogene 1 |
| chr17_+_24720063 | 2.84 |
ENSMUST00000170715.1
ENSMUST00000054289.6 ENSMUST00000146867.1 |
Rps2
|
ribosomal protein S2 |
| chr13_-_23571151 | 2.81 |
ENSMUST00000102969.3
|
Hist1h2ae
|
histone cluster 1, H2ae |
| chr2_+_153918391 | 2.81 |
ENSMUST00000109760.1
|
Bpifb3
|
BPI fold containing family B, member 3 |
| chr2_+_153938218 | 2.80 |
ENSMUST00000109757.1
|
Bpifb4
|
BPI fold containing family B, member 4 |
| chr7_-_30457515 | 2.76 |
ENSMUST00000045817.7
|
Kirrel2
|
kin of IRRE like 2 (Drosophila) |
| chr9_+_44334685 | 2.76 |
ENSMUST00000052686.2
|
H2afx
|
H2A histone family, member X |
| chr17_-_80207299 | 2.76 |
ENSMUST00000063417.9
|
Srsf7
|
serine/arginine-rich splicing factor 7 |
| chr19_+_8723478 | 2.75 |
ENSMUST00000180819.1
ENSMUST00000181422.1 |
Snhg1
|
small nucleolar RNA host gene (non-protein coding) 1 |
| chr14_-_56778301 | 2.73 |
ENSMUST00000022507.5
ENSMUST00000163924.1 |
Pspc1
|
paraspeckle protein 1 |
| chr2_+_152736244 | 2.73 |
ENSMUST00000038368.8
ENSMUST00000109824.1 |
Id1
|
inhibitor of DNA binding 1 |
| chr11_-_106301801 | 2.72 |
ENSMUST00000103071.3
|
Gh
|
growth hormone |
| chr17_-_35074485 | 2.71 |
ENSMUST00000007259.3
|
Ly6g6d
|
lymphocyte antigen 6 complex, locus G6D |
| chr13_+_23574381 | 2.69 |
ENSMUST00000090776.4
|
Hist1h2ad
|
histone cluster 1, H2ad |
| chr10_+_79988584 | 2.69 |
ENSMUST00000004784.4
ENSMUST00000105374.1 |
Cnn2
|
calponin 2 |
| chr10_-_40302186 | 2.66 |
ENSMUST00000099945.4
|
Amd1
|
S-adenosylmethionine decarboxylase 1 |
| chr14_+_67745229 | 2.66 |
ENSMUST00000111095.2
|
Gnrh1
|
gonadotropin releasing hormone 1 |
| chr14_+_68083853 | 2.64 |
ENSMUST00000022639.7
|
Nefl
|
neurofilament, light polypeptide |
| chr17_-_6827990 | 2.59 |
ENSMUST00000181895.1
|
Gm2885
|
predicted gene 2885 |
| chr5_+_115559467 | 2.58 |
ENSMUST00000086519.5
|
Rplp0
|
ribosomal protein, large, P0 |
| chr17_+_29032664 | 2.57 |
ENSMUST00000130216.1
|
Srsf3
|
serine/arginine-rich splicing factor 3 |
| chr5_+_115559505 | 2.57 |
ENSMUST00000156359.1
ENSMUST00000152976.1 |
Rplp0
|
ribosomal protein, large, P0 |
| chr9_+_55541148 | 2.57 |
ENSMUST00000034869.4
|
Isl2
|
insulin related protein 2 (islet 2) |
| chr10_-_128626464 | 2.56 |
ENSMUST00000026420.5
|
Rps26
|
ribosomal protein S26 |
| chr9_-_88522876 | 2.56 |
ENSMUST00000180563.2
ENSMUST00000183030.1 ENSMUST00000182232.1 |
Snhg5
|
small nucleolar RNA host gene 5 |
| chr7_-_142899985 | 2.56 |
ENSMUST00000000219.3
|
Th
|
tyrosine hydroxylase |
| chr8_-_13254068 | 2.56 |
ENSMUST00000168498.1
|
Adprhl1
|
ADP-ribosylhydrolase like 1 |
| chr8_-_13254096 | 2.55 |
ENSMUST00000171619.1
|
Adprhl1
|
ADP-ribosylhydrolase like 1 |
| chr18_-_36766198 | 2.50 |
ENSMUST00000061522.7
|
Dnd1
|
dead end homolog 1 (zebrafish) |
| chr8_-_70839720 | 2.46 |
ENSMUST00000002989.9
|
Arrdc2
|
arrestin domain containing 2 |
| chr4_+_86930691 | 2.44 |
ENSMUST00000164590.1
|
Acer2
|
alkaline ceramidase 2 |
| chr13_-_21750505 | 2.43 |
ENSMUST00000102983.1
|
Hist1h4k
|
histone cluster 1, H4k |
| chr12_+_85473883 | 2.41 |
ENSMUST00000021674.6
|
Fos
|
FBJ osteosarcoma oncogene |
| chr4_+_41966058 | 2.40 |
ENSMUST00000108026.2
|
Gm20938
|
predicted gene, 20938 |
| chrX_+_74270812 | 2.40 |
ENSMUST00000008826.7
ENSMUST00000151702.1 ENSMUST00000074085.5 ENSMUST00000135690.1 |
Rpl10
|
ribosomal protein L10 |
| chr4_-_116627921 | 2.39 |
ENSMUST00000030456.7
|
Nasp
|
nuclear autoantigenic sperm protein (histone-binding) |
| chr19_+_39113898 | 2.35 |
ENSMUST00000087234.2
|
Cyp2c66
|
cytochrome P450, family 2, subfamily c, polypeptide 66 |
| chr14_-_79771305 | 2.35 |
ENSMUST00000039568.5
|
Pcdh8
|
protocadherin 8 |
Network of associatons between targets according to the STRING database.
First level regulatory network of Tbp
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 8.8 | 26.4 | GO:0002148 | hypochlorous acid metabolic process(GO:0002148) hypochlorous acid biosynthetic process(GO:0002149) |
| 8.3 | 24.8 | GO:0070488 | neutrophil aggregation(GO:0070488) |
| 5.0 | 19.9 | GO:0035524 | proline transmembrane transport(GO:0035524) glycine import(GO:0036233) |
| 4.5 | 13.5 | GO:0051464 | positive regulation of cortisol secretion(GO:0051464) |
| 4.2 | 12.6 | GO:0071918 | urea transmembrane transport(GO:0071918) |
| 3.9 | 11.8 | GO:1902310 | positive regulation of peptidyl-serine dephosphorylation(GO:1902310) |
| 3.9 | 31.5 | GO:0015671 | oxygen transport(GO:0015671) |
| 3.7 | 11.0 | GO:0002842 | positive regulation of T cell mediated immune response to tumor cell(GO:0002842) |
| 3.4 | 10.3 | GO:0060722 | spongiotrophoblast cell proliferation(GO:0060720) cell proliferation involved in embryonic placenta development(GO:0060722) |
| 3.3 | 26.6 | GO:0006776 | vitamin A metabolic process(GO:0006776) |
| 3.3 | 9.8 | GO:0090649 | response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650) |
| 2.5 | 19.9 | GO:0097647 | calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647) |
| 2.5 | 9.9 | GO:0045091 | regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091) |
| 2.5 | 12.4 | GO:0090191 | negative regulation of branching involved in ureteric bud morphogenesis(GO:0090191) |
| 2.5 | 9.8 | GO:0021941 | negative regulation of cerebellar granule cell precursor proliferation(GO:0021941) |
| 2.3 | 21.1 | GO:0070944 | neutrophil mediated killing of bacterium(GO:0070944) |
| 2.3 | 18.4 | GO:0010624 | regulation of Schwann cell proliferation(GO:0010624) |
| 2.2 | 6.6 | GO:0046005 | positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005) |
| 2.1 | 8.5 | GO:0035519 | protein K29-linked ubiquitination(GO:0035519) |
| 2.0 | 4.0 | GO:0006407 | rRNA export from nucleus(GO:0006407) |
| 2.0 | 25.5 | GO:0002002 | regulation of angiotensin levels in blood(GO:0002002) |
| 1.9 | 23.4 | GO:0002679 | respiratory burst involved in defense response(GO:0002679) |
| 1.9 | 5.8 | GO:0000320 | re-entry into mitotic cell cycle(GO:0000320) |
| 1.8 | 12.7 | GO:0010273 | detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169) |
| 1.7 | 12.2 | GO:0035948 | positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) |
| 1.6 | 4.8 | GO:2000402 | negative regulation of lymphocyte migration(GO:2000402) |
| 1.5 | 40.2 | GO:0045109 | intermediate filament organization(GO:0045109) |
| 1.5 | 4.4 | GO:1901355 | response to rapamycin(GO:1901355) |
| 1.5 | 46.5 | GO:0006335 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) |
| 1.4 | 9.8 | GO:0051725 | protein de-ADP-ribosylation(GO:0051725) |
| 1.3 | 5.3 | GO:0046351 | disaccharide biosynthetic process(GO:0046351) |
| 1.3 | 6.6 | GO:0036414 | protein citrullination(GO:0018101) histone citrullination(GO:0036414) |
| 1.3 | 24.6 | GO:0033275 | actin-myosin filament sliding(GO:0033275) |
| 1.3 | 3.8 | GO:0003218 | cardiac left ventricle formation(GO:0003218) |
| 1.2 | 7.2 | GO:0036476 | neuron death in response to hydrogen peroxide(GO:0036476) regulation of hydrogen peroxide-induced neuron death(GO:1903207) negative regulation of hydrogen peroxide-induced neuron death(GO:1903208) |
| 1.2 | 3.5 | GO:0007439 | ectodermal digestive tract development(GO:0007439) embryonic ectodermal digestive tract development(GO:0048611) |
| 1.1 | 6.8 | GO:0002430 | complement receptor mediated signaling pathway(GO:0002430) |
| 1.0 | 6.2 | GO:0061641 | CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641) |
| 1.0 | 5.1 | GO:0098528 | skeletal muscle fiber differentiation(GO:0098528) |
| 1.0 | 4.0 | GO:1902896 | terminal web assembly(GO:1902896) |
| 1.0 | 9.6 | GO:0035873 | lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879) |
| 1.0 | 13.4 | GO:0046884 | follicle-stimulating hormone secretion(GO:0046884) |
| 0.9 | 14.4 | GO:0032096 | negative regulation of response to food(GO:0032096) |
| 0.9 | 2.7 | GO:0006597 | spermine biosynthetic process(GO:0006597) |
| 0.9 | 14.0 | GO:0071688 | striated muscle myosin thick filament assembly(GO:0071688) |
| 0.9 | 5.2 | GO:0030913 | paranodal junction assembly(GO:0030913) |
| 0.9 | 2.6 | GO:0021524 | visceral motor neuron differentiation(GO:0021524) |
| 0.9 | 2.6 | GO:0042414 | epinephrine metabolic process(GO:0042414) |
| 0.8 | 5.9 | GO:2000491 | positive regulation of hepatic stellate cell activation(GO:2000491) |
| 0.8 | 2.4 | GO:0090285 | negative regulation of protein glycosylation in Golgi(GO:0090285) |
| 0.8 | 15.4 | GO:0000920 | cell separation after cytokinesis(GO:0000920) |
| 0.7 | 2.2 | GO:0046333 | octopamine biosynthetic process(GO:0006589) octopamine metabolic process(GO:0046333) |
| 0.7 | 14.1 | GO:1900151 | regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153) |
| 0.7 | 5.2 | GO:0016584 | nucleosome positioning(GO:0016584) |
| 0.6 | 3.2 | GO:0090027 | negative regulation of monocyte chemotaxis(GO:0090027) |
| 0.6 | 1.8 | GO:0071462 | cellular response to mercury ion(GO:0071288) cellular response to water stimulus(GO:0071462) |
| 0.6 | 8.2 | GO:0007076 | mitotic chromosome condensation(GO:0007076) |
| 0.6 | 2.3 | GO:0032696 | negative regulation of interleukin-13 production(GO:0032696) |
| 0.5 | 3.2 | GO:0051105 | regulation of DNA ligation(GO:0051105) positive regulation of DNA ligation(GO:0051106) |
| 0.5 | 3.6 | GO:0036072 | intramembranous ossification(GO:0001957) direct ossification(GO:0036072) |
| 0.5 | 7.1 | GO:0010529 | regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529) |
| 0.5 | 3.5 | GO:0045876 | positive regulation of sister chromatid cohesion(GO:0045876) |
| 0.5 | 2.5 | GO:0043137 | DNA replication, removal of RNA primer(GO:0043137) |
| 0.5 | 0.9 | GO:0071442 | positive regulation of histone H3-K14 acetylation(GO:0071442) |
| 0.4 | 5.8 | GO:0032926 | negative regulation of activin receptor signaling pathway(GO:0032926) |
| 0.4 | 2.7 | GO:2000354 | regulation of ovarian follicle development(GO:2000354) |
| 0.4 | 1.2 | GO:1903279 | regulation of calcium:sodium antiporter activity(GO:1903279) |
| 0.4 | 55.6 | GO:0007586 | digestion(GO:0007586) |
| 0.4 | 7.6 | GO:0000028 | ribosomal small subunit assembly(GO:0000028) |
| 0.4 | 2.7 | GO:1903026 | negative regulation of protein homodimerization activity(GO:0090074) negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026) |
| 0.4 | 3.9 | GO:0001867 | complement activation, lectin pathway(GO:0001867) |
| 0.4 | 22.0 | GO:1900026 | positive regulation of substrate adhesion-dependent cell spreading(GO:1900026) |
| 0.4 | 4.2 | GO:0071280 | cellular response to copper ion(GO:0071280) |
| 0.4 | 1.1 | GO:0009414 | hexitol metabolic process(GO:0006059) response to water deprivation(GO:0009414) inner medullary collecting duct development(GO:0072061) |
| 0.4 | 1.1 | GO:1900738 | positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738) |
| 0.4 | 6.9 | GO:0001833 | inner cell mass cell proliferation(GO:0001833) |
| 0.4 | 1.4 | GO:0071638 | negative regulation of monocyte chemotactic protein-1 production(GO:0071638) |
| 0.4 | 10.9 | GO:0071470 | cellular response to osmotic stress(GO:0071470) |
| 0.3 | 10.0 | GO:0031424 | keratinization(GO:0031424) |
| 0.3 | 3.6 | GO:0061469 | regulation of type B pancreatic cell proliferation(GO:0061469) |
| 0.3 | 2.1 | GO:1904798 | positive regulation of core promoter binding(GO:1904798) |
| 0.3 | 2.3 | GO:0071816 | maintenance of unfolded protein(GO:0036506) tail-anchored membrane protein insertion into ER membrane(GO:0071816) maintenance of unfolded protein involved in ERAD pathway(GO:1904378) |
| 0.3 | 9.3 | GO:0071353 | cellular response to interleukin-4(GO:0071353) |
| 0.3 | 2.0 | GO:0030644 | cellular chloride ion homeostasis(GO:0030644) |
| 0.3 | 12.8 | GO:0045071 | negative regulation of viral genome replication(GO:0045071) |
| 0.2 | 3.2 | GO:0002043 | blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043) |
| 0.2 | 3.9 | GO:0051984 | positive regulation of chromosome segregation(GO:0051984) |
| 0.2 | 0.7 | GO:0021590 | cerebellum maturation(GO:0021590) cerebellar Purkinje cell layer maturation(GO:0021691) cerebellar cortex maturation(GO:0021699) |
| 0.2 | 1.7 | GO:1900034 | regulation of cellular response to heat(GO:1900034) |
| 0.2 | 7.4 | GO:0015804 | neutral amino acid transport(GO:0015804) |
| 0.2 | 1.3 | GO:0021886 | hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888) |
| 0.2 | 1.5 | GO:2000344 | positive regulation of acrosome reaction(GO:2000344) |
| 0.2 | 1.5 | GO:0060837 | blood vessel endothelial cell differentiation(GO:0060837) |
| 0.2 | 6.1 | GO:0000387 | spliceosomal snRNP assembly(GO:0000387) |
| 0.2 | 0.5 | GO:0070213 | protein auto-ADP-ribosylation(GO:0070213) |
| 0.2 | 8.3 | GO:0006182 | cGMP biosynthetic process(GO:0006182) |
| 0.2 | 0.6 | GO:0034124 | regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124) |
| 0.2 | 14.0 | GO:0010923 | negative regulation of phosphatase activity(GO:0010923) |
| 0.2 | 2.2 | GO:0035970 | peptidyl-threonine dephosphorylation(GO:0035970) |
| 0.2 | 11.2 | GO:0006334 | nucleosome assembly(GO:0006334) |
| 0.2 | 5.0 | GO:0051290 | protein heterotetramerization(GO:0051290) |
| 0.1 | 6.1 | GO:0033119 | negative regulation of RNA splicing(GO:0033119) |
| 0.1 | 0.6 | GO:0006556 | S-adenosylmethionine biosynthetic process(GO:0006556) |
| 0.1 | 1.2 | GO:0014807 | regulation of somitogenesis(GO:0014807) |
| 0.1 | 5.5 | GO:0030225 | macrophage differentiation(GO:0030225) |
| 0.1 | 4.2 | GO:0040034 | regulation of development, heterochronic(GO:0040034) |
| 0.1 | 2.7 | GO:0050765 | negative regulation of phagocytosis(GO:0050765) |
| 0.1 | 2.5 | GO:0060965 | negative regulation of gene silencing by miRNA(GO:0060965) |
| 0.1 | 2.7 | GO:0090031 | positive regulation of steroid hormone biosynthetic process(GO:0090031) |
| 0.1 | 0.6 | GO:2000609 | regulation of thyroid hormone generation(GO:2000609) |
| 0.1 | 1.8 | GO:0007175 | negative regulation of epidermal growth factor-activated receptor activity(GO:0007175) |
| 0.1 | 18.4 | GO:0010951 | negative regulation of endopeptidase activity(GO:0010951) |
| 0.1 | 11.9 | GO:0043627 | response to estrogen(GO:0043627) |
| 0.1 | 12.6 | GO:0006342 | chromatin silencing(GO:0006342) |
| 0.1 | 8.3 | GO:0030512 | negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) |
| 0.1 | 2.4 | GO:0045672 | positive regulation of osteoclast differentiation(GO:0045672) |
| 0.1 | 0.6 | GO:0048686 | regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690) |
| 0.1 | 0.8 | GO:2000253 | positive regulation of feeding behavior(GO:2000253) |
| 0.1 | 8.2 | GO:0061515 | myeloid cell development(GO:0061515) |
| 0.1 | 1.6 | GO:0048672 | positive regulation of collateral sprouting(GO:0048672) |
| 0.1 | 2.7 | GO:1905144 | acetylcholine receptor signaling pathway(GO:0095500) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145) |
| 0.1 | 0.6 | GO:2000271 | positive regulation of fibroblast apoptotic process(GO:2000271) |
| 0.1 | 4.9 | GO:0000245 | spliceosomal complex assembly(GO:0000245) |
| 0.1 | 0.5 | GO:0007000 | nucleolus organization(GO:0007000) |
| 0.1 | 1.8 | GO:0001580 | detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580) |
| 0.1 | 0.5 | GO:0051459 | corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461) |
| 0.1 | 1.0 | GO:0043968 | histone H2A acetylation(GO:0043968) |
| 0.1 | 0.6 | GO:0030823 | regulation of cGMP metabolic process(GO:0030823) |
| 0.1 | 1.3 | GO:0031280 | negative regulation of adenylate cyclase activity(GO:0007194) negative regulation of cyclase activity(GO:0031280) |
| 0.1 | 1.8 | GO:0002026 | regulation of the force of heart contraction(GO:0002026) |
| 0.1 | 1.4 | GO:0032332 | positive regulation of chondrocyte differentiation(GO:0032332) |
| 0.1 | 2.4 | GO:0000027 | ribosomal large subunit assembly(GO:0000027) |
| 0.1 | 0.4 | GO:1901907 | diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911) |
| 0.1 | 0.7 | GO:0007342 | fusion of sperm to egg plasma membrane(GO:0007342) |
| 0.1 | 1.2 | GO:0035414 | negative regulation of catenin import into nucleus(GO:0035414) |
| 0.1 | 0.6 | GO:0060689 | cell differentiation involved in salivary gland development(GO:0060689) |
| 0.1 | 0.4 | GO:0086073 | bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073) |
| 0.1 | 1.2 | GO:0007625 | grooming behavior(GO:0007625) |
| 0.1 | 5.2 | GO:0046546 | male gonad development(GO:0008584) development of primary male sexual characteristics(GO:0046546) |
| 0.0 | 0.4 | GO:0099590 | neurotransmitter receptor internalization(GO:0099590) |
| 0.0 | 1.5 | GO:0019236 | response to pheromone(GO:0019236) |
| 0.0 | 2.3 | GO:0002181 | cytoplasmic translation(GO:0002181) |
| 0.0 | 1.8 | GO:0006414 | translational elongation(GO:0006414) |
| 0.0 | 0.3 | GO:0035457 | cellular response to interferon-alpha(GO:0035457) |
| 0.0 | 0.2 | GO:2000051 | negative regulation of non-canonical Wnt signaling pathway(GO:2000051) |
| 0.0 | 0.4 | GO:0070884 | regulation of calcineurin-NFAT signaling cascade(GO:0070884) |
| 0.0 | 0.3 | GO:0043653 | mitochondrial fragmentation involved in apoptotic process(GO:0043653) |
| 0.0 | 2.0 | GO:0051965 | positive regulation of synapse assembly(GO:0051965) |
| 0.0 | 1.2 | GO:0007585 | respiratory gaseous exchange(GO:0007585) |
| 0.0 | 2.6 | GO:0051028 | mRNA transport(GO:0051028) |
| 0.0 | 0.9 | GO:0021591 | ventricular system development(GO:0021591) |
| 0.0 | 0.7 | GO:0009268 | response to pH(GO:0009268) |
| 0.0 | 0.7 | GO:0035690 | cellular response to drug(GO:0035690) |
| 0.0 | 0.1 | GO:0042255 | ribosome assembly(GO:0042255) |
| 0.0 | 2.1 | GO:0002244 | hematopoietic progenitor cell differentiation(GO:0002244) |
| 0.0 | 1.4 | GO:0072332 | intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332) |
| 0.0 | 0.1 | GO:0030259 | lipid glycosylation(GO:0030259) |
| 0.0 | 0.1 | GO:0006172 | ADP biosynthetic process(GO:0006172) |
| 0.0 | 2.2 | GO:0016331 | morphogenesis of embryonic epithelium(GO:0016331) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 7.0 | 56.4 | GO:0005833 | hemoglobin complex(GO:0005833) |
| 4.6 | 18.4 | GO:0097450 | astrocyte end-foot(GO:0097450) |
| 2.6 | 26.4 | GO:0005766 | primary lysosome(GO:0005766) azurophil granule(GO:0042582) |
| 1.8 | 28.3 | GO:0042581 | specific granule(GO:0042581) |
| 1.2 | 3.6 | GO:0005584 | collagen type I trimer(GO:0005584) |
| 1.2 | 6.9 | GO:0030670 | phagocytic vesicle membrane(GO:0030670) |
| 1.1 | 2.2 | GO:0060205 | secretory granule lumen(GO:0034774) cytoplasmic membrane-bounded vesicle lumen(GO:0060205) |
| 1.1 | 12.2 | GO:0032982 | myosin filament(GO:0032982) |
| 1.0 | 36.4 | GO:0000788 | nuclear nucleosome(GO:0000788) |
| 0.9 | 4.5 | GO:0034715 | U7 snRNP(GO:0005683) pICln-Sm protein complex(GO:0034715) |
| 0.9 | 2.6 | GO:0033596 | TSC1-TSC2 complex(GO:0033596) |
| 0.8 | 11.8 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
| 0.8 | 5.9 | GO:0030485 | smooth muscle contractile fiber(GO:0030485) |
| 0.8 | 6.2 | GO:0042382 | paraspeckles(GO:0042382) |
| 0.8 | 33.1 | GO:0000786 | nucleosome(GO:0000786) |
| 0.7 | 3.5 | GO:1990745 | EARP complex(GO:1990745) |
| 0.6 | 10.9 | GO:0032593 | insulin-responsive compartment(GO:0032593) |
| 0.6 | 5.0 | GO:0045098 | type III intermediate filament(GO:0045098) |
| 0.6 | 14.9 | GO:0042588 | zymogen granule(GO:0042588) |
| 0.6 | 4.0 | GO:1990357 | terminal web(GO:1990357) |
| 0.6 | 2.2 | GO:0032021 | NELF complex(GO:0032021) |
| 0.5 | 14.0 | GO:0005859 | muscle myosin complex(GO:0005859) |
| 0.5 | 54.2 | GO:0005882 | intermediate filament(GO:0005882) |
| 0.5 | 1.6 | GO:0071007 | U2-type catalytic step 2 spliceosome(GO:0071007) |
| 0.5 | 2.9 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
| 0.5 | 11.0 | GO:0031362 | anchored component of external side of plasma membrane(GO:0031362) |
| 0.5 | 1.4 | GO:0031074 | nucleocytoplasmic shuttling complex(GO:0031074) |
| 0.4 | 1.8 | GO:0031310 | integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310) |
| 0.4 | 2.5 | GO:0032299 | ribonuclease H2 complex(GO:0032299) |
| 0.4 | 2.4 | GO:0035976 | AP1 complex(GO:0035976) |
| 0.4 | 2.6 | GO:0033162 | melanosome membrane(GO:0033162) chitosome(GO:0045009) |
| 0.4 | 3.2 | GO:0016012 | sarcoglycan complex(GO:0016012) |
| 0.3 | 8.6 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
| 0.3 | 2.3 | GO:0071818 | BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379) |
| 0.3 | 16.6 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 0.3 | 2.7 | GO:0098554 | cytoplasmic side of endoplasmic reticulum membrane(GO:0098554) |
| 0.3 | 2.1 | GO:0097550 | transcriptional preinitiation complex(GO:0097550) |
| 0.3 | 1.1 | GO:0097454 | Schwann cell microvillus(GO:0097454) |
| 0.3 | 4.0 | GO:0031616 | spindle pole centrosome(GO:0031616) |
| 0.3 | 3.8 | GO:0042405 | nuclear inclusion body(GO:0042405) |
| 0.2 | 6.2 | GO:0010369 | chromocenter(GO:0010369) |
| 0.2 | 15.4 | GO:0005871 | kinesin complex(GO:0005871) |
| 0.2 | 1.1 | GO:0072357 | PTW/PP1 phosphatase complex(GO:0072357) |
| 0.2 | 2.2 | GO:0097208 | alveolar lamellar body(GO:0097208) |
| 0.2 | 6.9 | GO:0001533 | cornified envelope(GO:0001533) |
| 0.2 | 0.6 | GO:0072534 | perineuronal net(GO:0072534) |
| 0.2 | 3.1 | GO:0017101 | aminoacyl-tRNA synthetase multienzyme complex(GO:0017101) |
| 0.2 | 1.9 | GO:0045298 | tubulin complex(GO:0045298) |
| 0.2 | 0.6 | GO:0048269 | methionine adenosyltransferase complex(GO:0048269) |
| 0.2 | 2.8 | GO:0036057 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
| 0.2 | 11.9 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.1 | 14.0 | GO:0005814 | centriole(GO:0005814) |
| 0.1 | 8.2 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
| 0.1 | 10.7 | GO:0016328 | lateral plasma membrane(GO:0016328) |
| 0.1 | 1.2 | GO:0090533 | cation-transporting ATPase complex(GO:0090533) |
| 0.1 | 34.4 | GO:0030141 | secretory granule(GO:0030141) |
| 0.1 | 4.2 | GO:0005876 | spindle microtubule(GO:0005876) |
| 0.1 | 1.0 | GO:0000812 | Swr1 complex(GO:0000812) |
| 0.1 | 2.0 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 0.1 | 7.5 | GO:0001750 | photoreceptor outer segment(GO:0001750) |
| 0.1 | 3.2 | GO:0035861 | site of double-strand break(GO:0035861) |
| 0.1 | 10.2 | GO:0042641 | actomyosin(GO:0042641) |
| 0.1 | 0.5 | GO:0017071 | intracellular cyclic nucleotide activated cation channel complex(GO:0017071) |
| 0.1 | 0.4 | GO:0005916 | fascia adherens(GO:0005916) |
| 0.1 | 4.9 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.1 | 2.4 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
| 0.0 | 9.7 | GO:0043209 | myelin sheath(GO:0043209) |
| 0.0 | 0.7 | GO:0005922 | connexon complex(GO:0005922) |
| 0.0 | 6.8 | GO:0098857 | membrane raft(GO:0045121) membrane microdomain(GO:0098857) |
| 0.0 | 1.8 | GO:0016459 | myosin complex(GO:0016459) |
| 0.0 | 14.9 | GO:0005774 | vacuolar membrane(GO:0005774) |
| 0.0 | 15.9 | GO:0000790 | nuclear chromatin(GO:0000790) |
| 0.0 | 4.2 | GO:0005923 | bicellular tight junction(GO:0005923) |
| 0.0 | 0.6 | GO:0005736 | DNA-directed RNA polymerase I complex(GO:0005736) |
| 0.0 | 0.5 | GO:0000242 | pericentriolar material(GO:0000242) |
| 0.0 | 8.3 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
| 0.0 | 8.8 | GO:0043025 | neuronal cell body(GO:0043025) |
| 0.0 | 0.7 | GO:0000118 | histone deacetylase complex(GO:0000118) |
| 0.0 | 0.4 | GO:0030131 | clathrin adaptor complex(GO:0030131) |
| 0.0 | 14.2 | GO:0030054 | cell junction(GO:0030054) |
| 0.0 | 3.1 | GO:0098590 | plasma membrane region(GO:0098590) |
| 0.0 | 9.0 | GO:0005730 | nucleolus(GO:0005730) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 14.1 | 56.4 | GO:0031721 | hemoglobin alpha binding(GO:0031721) |
| 9.8 | 9.8 | GO:0015254 | glycerol channel activity(GO:0015254) |
| 6.6 | 19.9 | GO:0005302 | L-tyrosine transmembrane transporter activity(GO:0005302) |
| 3.3 | 9.8 | GO:0005330 | dopamine:sodium symporter activity(GO:0005330) |
| 3.1 | 24.8 | GO:0050786 | Toll-like receptor 4 binding(GO:0035662) RAGE receptor binding(GO:0050786) |
| 2.5 | 9.8 | GO:0003875 | ADP-ribosylarginine hydrolase activity(GO:0003875) |
| 2.2 | 10.9 | GO:0055056 | D-glucose transmembrane transporter activity(GO:0055056) |
| 2.1 | 10.7 | GO:0010853 | cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250) |
| 2.1 | 12.6 | GO:0015265 | urea channel activity(GO:0015265) |
| 2.0 | 9.9 | GO:0003918 | DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505) |
| 2.0 | 27.5 | GO:0016918 | retinal binding(GO:0016918) |
| 1.9 | 23.4 | GO:0008430 | selenium binding(GO:0008430) |
| 1.8 | 7.1 | GO:0047844 | deoxycytidine deaminase activity(GO:0047844) |
| 1.8 | 5.3 | GO:0004461 | lactose synthase activity(GO:0004461) |
| 1.7 | 6.8 | GO:0001847 | opsonin receptor activity(GO:0001847) |
| 1.7 | 8.5 | GO:0004966 | galanin receptor activity(GO:0004966) |
| 1.7 | 5.0 | GO:0016608 | growth hormone-releasing hormone activity(GO:0016608) |
| 1.5 | 7.3 | GO:0030280 | structural constituent of epidermis(GO:0030280) |
| 1.4 | 9.6 | GO:0015129 | lactate transmembrane transporter activity(GO:0015129) |
| 1.3 | 6.6 | GO:0004668 | protein-arginine deiminase activity(GO:0004668) |
| 1.2 | 4.8 | GO:0031727 | CCR2 chemokine receptor binding(GO:0031727) |
| 1.1 | 53.4 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
| 1.1 | 33.6 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
| 1.0 | 5.0 | GO:1990254 | keratin filament binding(GO:1990254) |
| 0.9 | 1.8 | GO:0015168 | glycerol transmembrane transporter activity(GO:0015168) |
| 0.9 | 2.6 | GO:0034617 | tetrahydrobiopterin binding(GO:0034617) |
| 0.8 | 2.4 | GO:0071633 | dihydroceramidase activity(GO:0071633) |
| 0.7 | 2.2 | GO:0004500 | dopamine beta-monooxygenase activity(GO:0004500) |
| 0.7 | 14.0 | GO:0097493 | structural molecule activity conferring elasticity(GO:0097493) |
| 0.7 | 5.0 | GO:0042289 | MHC class II protein binding(GO:0042289) |
| 0.6 | 9.4 | GO:0030296 | protein tyrosine kinase activator activity(GO:0030296) |
| 0.6 | 14.3 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
| 0.6 | 122.6 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.5 | 3.8 | GO:0000403 | Y-form DNA binding(GO:0000403) |
| 0.5 | 4.2 | GO:0008131 | primary amine oxidase activity(GO:0008131) |
| 0.5 | 1.5 | GO:0050253 | retinyl-palmitate esterase activity(GO:0050253) |
| 0.5 | 2.3 | GO:0019834 | phospholipase A2 inhibitor activity(GO:0019834) |
| 0.5 | 12.2 | GO:0000146 | microfilament motor activity(GO:0000146) |
| 0.4 | 4.0 | GO:0043023 | ribosomal large subunit binding(GO:0043023) |
| 0.4 | 23.0 | GO:0004601 | peroxidase activity(GO:0004601) |
| 0.4 | 2.2 | GO:0004724 | magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724) |
| 0.4 | 1.3 | GO:0035373 | chondroitin sulfate proteoglycan binding(GO:0035373) |
| 0.4 | 5.8 | GO:0048185 | activin binding(GO:0048185) |
| 0.4 | 2.7 | GO:0019808 | polyamine binding(GO:0019808) |
| 0.4 | 1.8 | GO:0008390 | testosterone 16-alpha-hydroxylase activity(GO:0008390) |
| 0.4 | 12.9 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
| 0.4 | 5.0 | GO:0035925 | mRNA 3'-UTR AU-rich region binding(GO:0035925) |
| 0.4 | 2.5 | GO:0004523 | RNA-DNA hybrid ribonuclease activity(GO:0004523) |
| 0.3 | 2.7 | GO:0005131 | growth hormone receptor binding(GO:0005131) |
| 0.3 | 8.2 | GO:0008143 | poly(A) binding(GO:0008143) |
| 0.3 | 2.0 | GO:0004111 | creatine kinase activity(GO:0004111) |
| 0.3 | 6.5 | GO:0008510 | sodium:bicarbonate symporter activity(GO:0008510) |
| 0.3 | 4.2 | GO:0008097 | 5S rRNA binding(GO:0008097) |
| 0.3 | 9.8 | GO:0004864 | protein phosphatase inhibitor activity(GO:0004864) |
| 0.3 | 2.7 | GO:0030550 | acetylcholine receptor inhibitor activity(GO:0030550) |
| 0.3 | 9.0 | GO:0008236 | serine-type peptidase activity(GO:0008236) |
| 0.3 | 1.4 | GO:0004720 | protein-lysine 6-oxidase activity(GO:0004720) |
| 0.3 | 3.6 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
| 0.3 | 17.4 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
| 0.3 | 11.7 | GO:0003785 | actin monomer binding(GO:0003785) |
| 0.3 | 15.5 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
| 0.2 | 1.7 | GO:0048495 | Roundabout binding(GO:0048495) |
| 0.2 | 5.7 | GO:0071855 | neuropeptide receptor binding(GO:0071855) |
| 0.2 | 5.5 | GO:0004190 | aspartic-type endopeptidase activity(GO:0004190) |
| 0.2 | 1.3 | GO:0004969 | histamine receptor activity(GO:0004969) |
| 0.2 | 2.6 | GO:1990825 | sequence-specific mRNA binding(GO:1990825) |
| 0.2 | 1.4 | GO:0003810 | protein-glutamine gamma-glutamyltransferase activity(GO:0003810) |
| 0.2 | 8.5 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
| 0.2 | 3.2 | GO:0003906 | DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906) |
| 0.2 | 6.9 | GO:0005044 | scavenger receptor activity(GO:0005044) |
| 0.2 | 1.1 | GO:0004032 | alditol:NADP+ 1-oxidoreductase activity(GO:0004032) |
| 0.2 | 3.6 | GO:0016208 | AMP binding(GO:0016208) |
| 0.2 | 7.4 | GO:0015175 | neutral amino acid transmembrane transporter activity(GO:0015175) |
| 0.2 | 12.4 | GO:0017022 | myosin binding(GO:0017022) |
| 0.1 | 15.4 | GO:0003777 | microtubule motor activity(GO:0003777) |
| 0.1 | 13.2 | GO:0000980 | RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980) |
| 0.1 | 17.7 | GO:0005178 | integrin binding(GO:0005178) |
| 0.1 | 22.4 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 0.1 | 2.7 | GO:0070628 | proteasome binding(GO:0070628) |
| 0.1 | 10.4 | GO:0097110 | scaffold protein binding(GO:0097110) |
| 0.1 | 1.5 | GO:0005068 | transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068) |
| 0.1 | 1.2 | GO:0015386 | potassium:proton antiporter activity(GO:0015386) |
| 0.1 | 2.5 | GO:0017091 | AU-rich element binding(GO:0017091) |
| 0.1 | 2.0 | GO:0001190 | transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811) |
| 0.1 | 5.3 | GO:0051879 | Hsp90 protein binding(GO:0051879) |
| 0.1 | 1.8 | GO:0003746 | translation elongation factor activity(GO:0003746) |
| 0.1 | 1.2 | GO:0070097 | delta-catenin binding(GO:0070097) |
| 0.1 | 0.7 | GO:0097157 | pre-mRNA intronic binding(GO:0097157) |
| 0.1 | 1.6 | GO:0017070 | U6 snRNA binding(GO:0017070) |
| 0.1 | 3.2 | GO:0016504 | peptidase activator activity(GO:0016504) |
| 0.1 | 0.5 | GO:0005052 | peroxisome matrix targeting signal-1 binding(GO:0005052) |
| 0.1 | 3.8 | GO:0043425 | bHLH transcription factor binding(GO:0043425) |
| 0.1 | 2.4 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.1 | 2.2 | GO:0046966 | thyroid hormone receptor binding(GO:0046966) |
| 0.1 | 0.4 | GO:0034432 | endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) |
| 0.1 | 0.4 | GO:0008597 | calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597) |
| 0.1 | 2.0 | GO:0043274 | phospholipase binding(GO:0043274) |
| 0.1 | 24.4 | GO:0045296 | cadherin binding(GO:0045296) |
| 0.1 | 1.4 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
| 0.1 | 7.7 | GO:0019903 | protein phosphatase binding(GO:0019903) |
| 0.1 | 7.2 | GO:0019838 | growth factor binding(GO:0019838) |
| 0.1 | 1.5 | GO:0016503 | pheromone receptor activity(GO:0016503) |
| 0.1 | 3.2 | GO:0005507 | copper ion binding(GO:0005507) |
| 0.1 | 2.3 | GO:0032266 | phosphatidylinositol-3-phosphate binding(GO:0032266) |
| 0.1 | 3.2 | GO:0019905 | syntaxin binding(GO:0019905) |
| 0.1 | 2.8 | GO:0003684 | damaged DNA binding(GO:0003684) |
| 0.0 | 9.5 | GO:0003729 | mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822) |
| 0.0 | 0.7 | GO:0005243 | gap junction channel activity(GO:0005243) |
| 0.0 | 0.1 | GO:0001962 | alpha-1,3-galactosyltransferase activity(GO:0001962) |
| 0.0 | 0.9 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
| 0.0 | 1.8 | GO:0004812 | aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876) |
| 0.0 | 0.9 | GO:0070888 | E-box binding(GO:0070888) |
| 0.0 | 0.6 | GO:0001054 | RNA polymerase I activity(GO:0001054) |
| 0.0 | 0.9 | GO:0001786 | phosphatidylserine binding(GO:0001786) |
| 0.0 | 5.7 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
| 0.0 | 10.2 | GO:0005198 | structural molecule activity(GO:0005198) |
| 0.0 | 2.2 | GO:0051087 | chaperone binding(GO:0051087) |
| 0.0 | 5.1 | GO:0008017 | microtubule binding(GO:0008017) |
| 0.0 | 3.0 | GO:0051015 | actin filament binding(GO:0051015) |
| 0.0 | 0.5 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
| 0.0 | 0.1 | GO:0004342 | glucosamine-6-phosphate deaminase activity(GO:0004342) |
| 0.0 | 0.6 | GO:0000979 | RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979) |
| 0.0 | 0.6 | GO:0031490 | chromatin DNA binding(GO:0031490) |
| 0.0 | 0.1 | GO:0016018 | cyclosporin A binding(GO:0016018) |
| 0.0 | 0.4 | GO:0030276 | clathrin binding(GO:0030276) |
| 0.0 | 0.1 | GO:0034450 | ubiquitin-ubiquitin ligase activity(GO:0034450) |
| 0.0 | 5.4 | GO:0003682 | chromatin binding(GO:0003682) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 25.7 | PID IL23 PATHWAY | IL23-mediated signaling events |
| 0.5 | 24.5 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.3 | 10.9 | PID INSULIN GLUCOSE PATHWAY | Insulin-mediated glucose transport |
| 0.2 | 12.7 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 0.2 | 23.0 | PID RB 1PATHWAY | Regulation of retinoblastoma protein |
| 0.2 | 16.9 | PID REG GR PATHWAY | Glucocorticoid receptor regulatory network |
| 0.2 | 3.6 | PID LYMPH ANGIOGENESIS PATHWAY | VEGFR3 signaling in lymphatic endothelium |
| 0.2 | 43.1 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.1 | 11.8 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
| 0.1 | 10.3 | PID HIF1 TFPATHWAY | HIF-1-alpha transcription factor network |
| 0.1 | 2.7 | PID IL3 PATHWAY | IL3-mediated signaling events |
| 0.1 | 8.0 | PID ECADHERIN STABILIZATION PATHWAY | Stabilization and expansion of the E-cadherin adherens junction |
| 0.1 | 12.2 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.1 | 3.2 | PID DNA PK PATHWAY | DNA-PK pathway in nonhomologous end joining |
| 0.1 | 4.3 | PID A6B1 A6B4 INTEGRIN PATHWAY | a6b1 and a6b4 Integrin signaling |
| 0.1 | 2.8 | PID ATM PATHWAY | ATM pathway |
| 0.1 | 2.6 | PID ATF2 PATHWAY | ATF-2 transcription factor network |
| 0.1 | 2.7 | PID AR NONGENOMIC PATHWAY | Nongenotropic Androgen signaling |
| 0.1 | 1.5 | SA B CELL RECEPTOR COMPLEXES | Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases. |
| 0.1 | 1.7 | PID GLYPICAN 1PATHWAY | Glypican 1 network |
| 0.1 | 2.0 | PID INTEGRIN A4B1 PATHWAY | Alpha4 beta1 integrin signaling events |
| 0.1 | 11.1 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.1 | 5.7 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
| 0.0 | 3.3 | PID BETA CATENIN NUC PATHWAY | Regulation of nuclear beta catenin signaling and target gene transcription |
| 0.0 | 2.2 | PID P53 REGULATION PATHWAY | p53 pathway |
| 0.0 | 0.6 | PID HDAC CLASSIII PATHWAY | Signaling events mediated by HDAC Class III |
| 0.0 | 1.2 | PID RHOA PATHWAY | RhoA signaling pathway |
| 0.0 | 2.1 | PID CXCR4 PATHWAY | CXCR4-mediated signaling events |
| 0.0 | 2.6 | PID PDGFRB PATHWAY | PDGFR-beta signaling pathway |
| 0.0 | 7.2 | NABA SECRETED FACTORS | Genes encoding secreted soluble factors |
| 0.0 | 2.9 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.0 | 0.4 | PID TCR CALCIUM PATHWAY | Calcium signaling in the CD4+ TCR pathway |
| 0.0 | 0.3 | PID P38 ALPHA BETA PATHWAY | Regulation of p38-alpha and p38-beta |
| 0.0 | 0.6 | PID SMAD2 3NUCLEAR PATHWAY | Regulation of nuclear SMAD2/3 signaling |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.1 | 17.2 | REACTOME HORMONE LIGAND BINDING RECEPTORS | Genes involved in Hormone ligand-binding receptors |
| 1.5 | 24.0 | REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION | Genes involved in Apoptosis induced DNA fragmentation |
| 1.0 | 51.7 | REACTOME RNA POL I PROMOTER OPENING | Genes involved in RNA Polymerase I Promoter Opening |
| 1.0 | 20.6 | REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
| 0.8 | 9.7 | REACTOME PASSIVE TRANSPORT BY AQUAPORINS | Genes involved in Passive Transport by Aquaporins |
| 0.7 | 10.9 | REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS | Genes involved in Facilitative Na+-independent glucose transporters |
| 0.7 | 11.9 | REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN | Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin |
| 0.6 | 9.6 | REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
| 0.6 | 15.4 | REACTOME KINESINS | Genes involved in Kinesins |
| 0.5 | 27.5 | REACTOME STRIATED MUSCLE CONTRACTION | Genes involved in Striated Muscle Contraction |
| 0.5 | 16.0 | REACTOME AMINE COMPOUND SLC TRANSPORTERS | Genes involved in Amine compound SLC transporters |
| 0.5 | 18.2 | REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
| 0.4 | 14.8 | REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS | Genes involved in Regulation of gene expression in beta cells |
| 0.4 | 10.3 | REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
| 0.4 | 16.2 | REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D | Genes involved in Metabolism of steroid hormones and vitamins A and D |
| 0.4 | 4.5 | REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS | Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs |
| 0.4 | 11.8 | REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING | Genes involved in Downregulation of TGF-beta receptor signaling |
| 0.3 | 18.6 | REACTOME NUCLEAR SIGNALING BY ERBB4 | Genes involved in Nuclear signaling by ERBB4 |
| 0.3 | 16.6 | REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
| 0.3 | 6.8 | REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS | Genes involved in Termination of O-glycan biosynthesis |
| 0.3 | 4.2 | REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION | Genes involved in Cyclin A/B1 associated events during G2/M transition |
| 0.3 | 4.8 | REACTOME AMINE DERIVED HORMONES | Genes involved in Amine-derived hormones |
| 0.2 | 3.6 | REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN | Genes involved in Platelet Adhesion to exposed collagen |
| 0.2 | 5.9 | REACTOME MUSCLE CONTRACTION | Genes involved in Muscle contraction |
| 0.2 | 10.6 | REACTOME PEPTIDE CHAIN ELONGATION | Genes involved in Peptide chain elongation |
| 0.2 | 2.4 | REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS | Genes involved in Activation of the AP-1 family of transcription factors |
| 0.1 | 3.1 | REACTOME MITOCHONDRIAL TRNA AMINOACYLATION | Genes involved in Mitochondrial tRNA aminoacylation |
| 0.1 | 2.6 | REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII | Genes involved in CREB phosphorylation through the activation of CaMKII |
| 0.1 | 5.3 | REACTOME CLEAVAGE OF GROWING TRANSCRIPT IN THE TERMINATION REGION | Genes involved in Cleavage of Growing Transcript in the Termination Region |
| 0.1 | 1.1 | REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 | Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1) |
| 0.1 | 1.2 | REACTOME HYALURONAN UPTAKE AND DEGRADATION | Genes involved in Hyaluronan uptake and degradation |
| 0.1 | 1.7 | REACTOME ACTIVATION OF RAC | Genes involved in Activation of Rac |
| 0.1 | 2.1 | REACTOME OTHER SEMAPHORIN INTERACTIONS | Genes involved in Other semaphorin interactions |
| 0.1 | 2.1 | REACTOME G ALPHA I SIGNALLING EVENTS | Genes involved in G alpha (i) signalling events |
| 0.1 | 5.1 | REACTOME MRNA SPLICING | Genes involved in mRNA Splicing |
| 0.1 | 7.0 | REACTOME LATE PHASE OF HIV LIFE CYCLE | Genes involved in Late Phase of HIV Life Cycle |
| 0.1 | 0.5 | REACTOME RNA POL I TRANSCRIPTION TERMINATION | Genes involved in RNA Polymerase I Transcription Termination |
| 0.1 | 3.2 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
| 0.1 | 14.2 | REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
| 0.1 | 2.4 | REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
| 0.1 | 0.6 | REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING | Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling |
| 0.1 | 1.5 | REACTOME REGULATION OF SIGNALING BY CBL | Genes involved in Regulation of signaling by CBL |
| 0.0 | 1.1 | REACTOME NEPHRIN INTERACTIONS | Genes involved in Nephrin interactions |
| 0.0 | 0.7 | REACTOME GAP JUNCTION ASSEMBLY | Genes involved in Gap junction assembly |
| 0.0 | 1.5 | REACTOME GLUCAGON TYPE LIGAND RECEPTORS | Genes involved in Glucagon-type ligand receptors |
| 0.0 | 0.9 | REACTOME MYOGENESIS | Genes involved in Myogenesis |
| 0.0 | 2.0 | REACTOME SIGNALING BY PDGF | Genes involved in Signaling by PDGF |
| 0.0 | 0.1 | REACTOME BINDING AND ENTRY OF HIV VIRION | Genes involved in Binding and entry of HIV virion |
| 0.0 | 0.4 | REACTOME RETROGRADE NEUROTROPHIN SIGNALLING | Genes involved in Retrograde neurotrophin signalling |