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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Sox7

Z-value: 0.90

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Transcription factors associated with Sox7

Gene Symbol Gene ID Gene Info
ENSMUSG00000063060.5 SRY (sex determining region Y)-box 7

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Sox7mm10_v2_chr14_+_63943666_63943687-0.316.5e-02Click!

Activity profile of Sox7 motif

Sorted Z-values of Sox7 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Sox7

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0042231 interleukin-13 biosynthetic process(GO:0042231)
0.3 1.1 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.3 4.6 GO:0001865 NK T cell differentiation(GO:0001865)
0.2 1.5 GO:0061113 pancreas morphogenesis(GO:0061113)
0.1 2.2 GO:0046415 urate metabolic process(GO:0046415)
0.1 1.1 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.1 2.1 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.1 0.8 GO:0035356 cellular triglyceride homeostasis(GO:0035356)
0.1 1.3 GO:0071236 cellular response to antibiotic(GO:0071236)
0.1 0.2 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.1 2.2 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.1 0.4 GO:0061092 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.1 0.2 GO:0009753 sesquiterpenoid metabolic process(GO:0006714) response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.1 1.7 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.1 GO:0007525 somatic muscle development(GO:0007525)
0.0 2.2 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 0.9 GO:0031572 G2 DNA damage checkpoint(GO:0031572)
0.0 0.0 GO:0002304 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.0 0.4 GO:0019236 response to pheromone(GO:0019236)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 2.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 1.1 GO:0071564 npBAF complex(GO:0071564)
0.0 0.4 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.8 GO:0033270 paranode region of axon(GO:0033270)
0.0 4.6 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 1.3 GO:0032587 ruffle membrane(GO:0032587)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.5 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.3 2.2 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661)
0.3 0.8 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.1 1.3 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 0.6 GO:0016649 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.1 2.2 GO:0042166 acetylcholine binding(GO:0042166)
0.1 0.4 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.1 4.6 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 0.2 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006) delta4-3-oxosteroid 5beta-reductase activity(GO:0047787)
0.0 0.9 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.9 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.8 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 1.5 GO:0098531 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 1.1 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.2 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0 0.4 GO:0016503 pheromone receptor activity(GO:0016503)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 4.6 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 1.1 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 0.8 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.7 PID AURORA B PATHWAY Aurora B signaling
0.0 1.1 PID AR TF PATHWAY Regulation of Androgen receptor activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.6 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.2 2.2 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 1.3 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.0 1.5 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 1.1 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.2 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.8 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis