avrg: GSE58827: Dynamics of the Mouse Liver
Gene Symbol | Gene ID | Gene Info |
---|---|---|
Smad3
|
ENSMUSG00000032402.6 | SMAD family member 3 |
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Smad3 | mm10_v2_chr9_-_63711969_63711994 | -0.25 | 1.4e-01 | Click! |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.7 | 2.9 | GO:0050960 | detection of temperature stimulus involved in thermoception(GO:0050960) response to capsazepine(GO:1901594) |
0.6 | 12.1 | GO:0045653 | negative regulation of megakaryocyte differentiation(GO:0045653) |
0.5 | 1.8 | GO:0046898 | response to cycloheximide(GO:0046898) |
0.2 | 1.0 | GO:0010040 | response to iron(II) ion(GO:0010040) |
0.1 | 1.0 | GO:0015722 | canalicular bile acid transport(GO:0015722) |
0.1 | 0.4 | GO:0046101 | germinal center B cell differentiation(GO:0002314) adenosine catabolic process(GO:0006154) purine nucleobase salvage(GO:0043096) hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101) purine deoxyribonucleoside metabolic process(GO:0046122) |
0.1 | 2.7 | GO:0002227 | innate immune response in mucosa(GO:0002227) |
0.1 | 0.4 | GO:0001180 | transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180) |
0.1 | 0.5 | GO:0038109 | response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109) positive regulation of gastro-intestinal system smooth muscle contraction(GO:1904306) |
0.1 | 0.3 | GO:1902630 | regulation of membrane hyperpolarization(GO:1902630) |
0.1 | 1.3 | GO:0034242 | negative regulation of syncytium formation by plasma membrane fusion(GO:0034242) |
0.1 | 0.3 | GO:0060618 | nipple development(GO:0060618) |
0.1 | 0.8 | GO:0071394 | cellular response to testosterone stimulus(GO:0071394) |
0.1 | 9.1 | GO:0006342 | chromatin silencing(GO:0006342) |
0.1 | 0.3 | GO:0051122 | hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122) |
0.1 | 0.2 | GO:1902226 | regulation of macrophage colony-stimulating factor signaling pathway(GO:1902226) regulation of response to macrophage colony-stimulating factor(GO:1903969) regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903972) |
0.1 | 0.2 | GO:0021691 | cerebellar Purkinje cell layer maturation(GO:0021691) |
0.1 | 0.5 | GO:0051025 | negative regulation of immunoglobulin secretion(GO:0051025) |
0.0 | 0.4 | GO:2000659 | regulation of interleukin-1-mediated signaling pathway(GO:2000659) |
0.0 | 0.2 | GO:0018197 | peptidyl-aspartic acid modification(GO:0018197) |
0.0 | 4.1 | GO:0006334 | nucleosome assembly(GO:0006334) |
0.0 | 0.4 | GO:0045631 | regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980) |
0.0 | 0.2 | GO:0015015 | heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015) |
0.0 | 0.2 | GO:0097428 | protein maturation by iron-sulfur cluster transfer(GO:0097428) |
0.0 | 0.3 | GO:0002862 | negative regulation of inflammatory response to antigenic stimulus(GO:0002862) |
0.0 | 0.7 | GO:0035634 | response to stilbenoid(GO:0035634) |
0.0 | 0.5 | GO:0031340 | positive regulation of vesicle fusion(GO:0031340) |
0.0 | 0.1 | GO:0070294 | renal sodium ion absorption(GO:0070294) |
0.0 | 0.6 | GO:1902042 | negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042) |
0.0 | 0.7 | GO:0042246 | tissue regeneration(GO:0042246) |
0.0 | 0.2 | GO:1900037 | regulation of cellular response to hypoxia(GO:1900037) |
0.0 | 0.4 | GO:0046325 | negative regulation of glucose import(GO:0046325) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 1.0 | GO:0046691 | intracellular canaliculus(GO:0046691) |
0.3 | 11.2 | GO:0000788 | nuclear nucleosome(GO:0000788) |
0.2 | 9.0 | GO:0000786 | nucleosome(GO:0000786) |
0.2 | 1.8 | GO:0097136 | Bcl-2 family protein complex(GO:0097136) |
0.1 | 0.2 | GO:1990682 | CSF1-CSF1R complex(GO:1990682) |
0.0 | 0.2 | GO:0031310 | integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310) |
0.0 | 0.4 | GO:0005736 | DNA-directed RNA polymerase I complex(GO:0005736) |
0.0 | 0.1 | GO:1990667 | PCSK9-AnxA2 complex(GO:1990667) |
0.0 | 0.2 | GO:0005869 | dynactin complex(GO:0005869) |
0.0 | 1.3 | GO:0032993 | protein-DNA complex(GO:0032993) |
0.0 | 0.1 | GO:0016593 | Cdc73/Paf1 complex(GO:0016593) |
0.0 | 0.1 | GO:0001520 | outer dense fiber(GO:0001520) |
0.0 | 4.9 | GO:0000790 | nuclear chromatin(GO:0000790) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 2.9 | GO:0097603 | temperature-gated ion channel activity(GO:0097603) |
0.3 | 0.8 | GO:0005009 | insulin-activated receptor activity(GO:0005009) pheromone activity(GO:0005186) |
0.2 | 1.8 | GO:0051434 | BH3 domain binding(GO:0051434) |
0.2 | 1.0 | GO:0008422 | beta-glucosidase activity(GO:0008422) |
0.1 | 0.8 | GO:0008568 | microtubule-severing ATPase activity(GO:0008568) |
0.1 | 0.3 | GO:0004052 | arachidonate 12-lipoxygenase activity(GO:0004052) |
0.1 | 0.4 | GO:0001179 | RNA polymerase I transcription factor binding(GO:0001179) |
0.1 | 1.0 | GO:0015250 | water channel activity(GO:0015250) |
0.1 | 0.2 | GO:0005157 | macrophage colony-stimulating factor receptor binding(GO:0005157) |
0.1 | 0.5 | GO:0004716 | receptor signaling protein tyrosine kinase activity(GO:0004716) |
0.0 | 12.1 | GO:0042393 | histone binding(GO:0042393) |
0.0 | 0.2 | GO:0017095 | heparan sulfate 6-O-sulfotransferase activity(GO:0017095) |
0.0 | 0.4 | GO:0004000 | adenosine deaminase activity(GO:0004000) |
0.0 | 0.3 | GO:0001640 | adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) |
0.0 | 1.3 | GO:0050699 | WW domain binding(GO:0050699) |
0.0 | 0.2 | GO:1990380 | Lys48-specific deubiquitinase activity(GO:1990380) |
0.0 | 0.3 | GO:0015279 | store-operated calcium channel activity(GO:0015279) |
0.0 | 0.7 | GO:0008392 | arachidonic acid epoxygenase activity(GO:0008392) |
0.0 | 0.3 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
0.0 | 0.1 | GO:0019834 | phospholipase A2 inhibitor activity(GO:0019834) |
0.0 | 0.3 | GO:0004602 | glutathione peroxidase activity(GO:0004602) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 1.8 | SA PROGRAMMED CELL DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
0.1 | 2.9 | PID MAPK TRK PATHWAY | Trk receptor signaling mediated by the MAPK pathway |
0.0 | 0.2 | SA MMP CYTOKINE CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
0.0 | 0.8 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 17.3 | REACTOME PACKAGING OF TELOMERE ENDS | Genes involved in Packaging Of Telomere Ends |
0.3 | 1.0 | REACTOME DIGESTION OF DIETARY CARBOHYDRATE | Genes involved in Digestion of dietary carbohydrate |
0.1 | 1.8 | REACTOME INFLAMMASOMES | Genes involved in Inflammasomes |
0.1 | 1.0 | REACTOME PASSIVE TRANSPORT BY AQUAPORINS | Genes involved in Passive Transport by Aquaporins |
0.0 | 0.3 | REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING | Genes involved in Role of second messengers in netrin-1 signaling |
0.0 | 0.4 | REACTOME PURINE SALVAGE | Genes involved in Purine salvage |
0.0 | 0.5 | REACTOME REGULATION OF KIT SIGNALING | Genes involved in Regulation of KIT signaling |
0.0 | 0.3 | REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |