avrg: GSE58827: Dynamics of the Mouse Liver
Gene Symbol | Gene ID | Gene Info |
---|---|---|
Msx2
|
ENSMUSG00000021469.8 | msh homeobox 2 |
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Msx2 | mm10_v2_chr13_-_53473074_53473074 | 0.40 | 1.7e-02 | Click! |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.2 | 4.7 | GO:0035566 | regulation of metanephros size(GO:0035566) |
1.0 | 4.2 | GO:1904395 | positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) |
0.8 | 17.9 | GO:2000251 | positive regulation of actin cytoskeleton reorganization(GO:2000251) |
0.5 | 1.6 | GO:1905000 | regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000) |
0.5 | 2.1 | GO:0043973 | histone H3-K4 acetylation(GO:0043973) |
0.4 | 1.6 | GO:0061743 | motor learning(GO:0061743) |
0.4 | 2.7 | GO:0098535 | positive regulation of centriole replication(GO:0046601) de novo centriole assembly(GO:0098535) |
0.4 | 2.2 | GO:0050916 | sensory perception of sweet taste(GO:0050916) |
0.4 | 5.4 | GO:0001778 | plasma membrane repair(GO:0001778) |
0.4 | 1.1 | GO:0031283 | negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283) |
0.3 | 0.9 | GO:2000016 | negative regulation of determination of dorsal identity(GO:2000016) |
0.3 | 0.9 | GO:1901994 | negative regulation of meiotic cell cycle phase transition(GO:1901994) |
0.3 | 1.5 | GO:1902748 | positive regulation of lens fiber cell differentiation(GO:1902748) |
0.2 | 1.1 | GO:0070171 | negative regulation of tooth mineralization(GO:0070171) |
0.2 | 0.9 | GO:0072344 | rescue of stalled ribosome(GO:0072344) |
0.2 | 1.3 | GO:0072318 | clathrin coat disassembly(GO:0072318) |
0.2 | 0.6 | GO:0090274 | positive regulation of somatostatin secretion(GO:0090274) |
0.2 | 1.5 | GO:1901164 | negative regulation of trophoblast cell migration(GO:1901164) |
0.2 | 1.3 | GO:0070294 | renal sodium ion absorption(GO:0070294) |
0.1 | 0.4 | GO:0090260 | corticospinal neuron axon guidance through spinal cord(GO:0021972) positive regulation of negative chemotaxis(GO:0050924) induction of negative chemotaxis(GO:0050929) negative regulation of mononuclear cell migration(GO:0071676) negative regulation of retinal ganglion cell axon guidance(GO:0090260) |
0.1 | 1.4 | GO:2000741 | positive regulation of mesenchymal stem cell differentiation(GO:2000741) |
0.1 | 0.4 | GO:0048690 | regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690) |
0.1 | 1.0 | GO:1903847 | regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849) |
0.1 | 1.1 | GO:0030916 | otic vesicle formation(GO:0030916) |
0.1 | 1.9 | GO:0048664 | neuron fate determination(GO:0048664) |
0.1 | 0.7 | GO:2001280 | positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280) |
0.1 | 4.9 | GO:0090162 | establishment of epithelial cell polarity(GO:0090162) |
0.1 | 0.3 | GO:0032685 | negative regulation of granulocyte macrophage colony-stimulating factor production(GO:0032685) |
0.1 | 1.7 | GO:0032060 | bleb assembly(GO:0032060) |
0.1 | 0.6 | GO:0021776 | smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776) |
0.1 | 1.3 | GO:0048739 | cardiac muscle fiber development(GO:0048739) |
0.1 | 1.1 | GO:0042541 | hemoglobin biosynthetic process(GO:0042541) |
0.1 | 0.2 | GO:0090526 | regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526) |
0.1 | 0.6 | GO:0016584 | nucleosome positioning(GO:0016584) |
0.1 | 0.4 | GO:0061641 | CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641) |
0.1 | 1.0 | GO:0048935 | peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935) |
0.1 | 1.5 | GO:0090036 | regulation of protein kinase C signaling(GO:0090036) |
0.1 | 1.8 | GO:0072520 | seminiferous tubule development(GO:0072520) |
0.1 | 4.0 | GO:0042982 | amyloid precursor protein metabolic process(GO:0042982) |
0.1 | 0.9 | GO:0001865 | NK T cell differentiation(GO:0001865) |
0.0 | 0.3 | GO:1903378 | positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378) |
0.0 | 0.2 | GO:0023016 | signal transduction by trans-phosphorylation(GO:0023016) |
0.0 | 1.4 | GO:0045109 | intermediate filament organization(GO:0045109) |
0.0 | 0.5 | GO:0019511 | peptidyl-proline hydroxylation(GO:0019511) |
0.0 | 0.5 | GO:0018231 | peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231) |
0.0 | 2.3 | GO:0016572 | histone phosphorylation(GO:0016572) |
0.0 | 0.8 | GO:0045898 | regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898) |
0.0 | 0.2 | GO:0043622 | cortical microtubule organization(GO:0043622) establishment of centrosome localization(GO:0051660) |
0.0 | 1.4 | GO:0045736 | negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030) |
0.0 | 0.7 | GO:0006999 | nuclear pore organization(GO:0006999) |
0.0 | 1.1 | GO:0046827 | positive regulation of protein export from nucleus(GO:0046827) |
0.0 | 0.2 | GO:0044828 | negative regulation by host of viral genome replication(GO:0044828) |
0.0 | 0.6 | GO:0060539 | diaphragm development(GO:0060539) |
0.0 | 1.6 | GO:0018279 | protein N-linked glycosylation via asparagine(GO:0018279) |
0.0 | 1.0 | GO:0045187 | regulation of circadian sleep/wake cycle, sleep(GO:0045187) |
0.0 | 1.3 | GO:0006730 | one-carbon metabolic process(GO:0006730) |
0.0 | 0.6 | GO:0050913 | sensory perception of bitter taste(GO:0050913) |
0.0 | 0.3 | GO:2001256 | regulation of store-operated calcium entry(GO:2001256) |
0.0 | 1.1 | GO:0019731 | antibacterial humoral response(GO:0019731) |
0.0 | 0.9 | GO:0019236 | response to pheromone(GO:0019236) |
0.0 | 0.4 | GO:0090083 | regulation of inclusion body assembly(GO:0090083) |
0.0 | 1.2 | GO:0006414 | translational elongation(GO:0006414) |
0.0 | 0.3 | GO:0046685 | response to arsenic-containing substance(GO:0046685) |
0.0 | 0.5 | GO:0060746 | parental behavior(GO:0060746) |
0.0 | 0.7 | GO:0033006 | regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304) |
0.0 | 0.3 | GO:0016973 | poly(A)+ mRNA export from nucleus(GO:0016973) |
0.0 | 0.1 | GO:0035063 | nuclear speck organization(GO:0035063) |
0.0 | 0.3 | GO:0000291 | nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) |
0.0 | 1.9 | GO:0002224 | toll-like receptor signaling pathway(GO:0002224) |
0.0 | 0.2 | GO:0035278 | miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974) |
0.0 | 0.6 | GO:0006383 | transcription from RNA polymerase III promoter(GO:0006383) |
0.0 | 0.3 | GO:0046855 | inositol phosphate dephosphorylation(GO:0046855) |
0.0 | 0.2 | GO:0002827 | positive regulation of T-helper 1 type immune response(GO:0002827) |
0.0 | 0.2 | GO:1901550 | regulation of endothelial cell development(GO:1901550) regulation of establishment of endothelial barrier(GO:1903140) |
0.0 | 0.7 | GO:0034605 | cellular response to heat(GO:0034605) |
0.0 | 0.3 | GO:0097352 | autophagosome maturation(GO:0097352) |
0.0 | 0.4 | GO:0001937 | negative regulation of endothelial cell proliferation(GO:0001937) |
0.0 | 0.7 | GO:0030819 | positive regulation of cAMP biosynthetic process(GO:0030819) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.5 | 17.9 | GO:0071439 | clathrin complex(GO:0071439) |
0.7 | 5.4 | GO:0005826 | actomyosin contractile ring(GO:0005826) |
0.5 | 2.7 | GO:0098536 | deuterosome(GO:0098536) |
0.4 | 1.6 | GO:0031523 | Myb complex(GO:0031523) |
0.3 | 2.3 | GO:0001940 | male pronucleus(GO:0001940) |
0.3 | 1.8 | GO:0005828 | kinetochore microtubule(GO:0005828) |
0.2 | 1.2 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
0.1 | 0.4 | GO:0072534 | perineuronal net(GO:0072534) |
0.1 | 0.7 | GO:0044615 | nuclear pore nuclear basket(GO:0044615) |
0.1 | 0.3 | GO:0031251 | PAN complex(GO:0031251) |
0.1 | 1.1 | GO:0044327 | dendritic spine head(GO:0044327) |
0.1 | 0.6 | GO:0000127 | transcription factor TFIIIC complex(GO:0000127) |
0.1 | 0.2 | GO:0002944 | cyclin K-CDK12 complex(GO:0002944) |
0.1 | 1.4 | GO:0030125 | clathrin vesicle coat(GO:0030125) |
0.1 | 0.3 | GO:1990452 | Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452) |
0.0 | 4.3 | GO:0031594 | neuromuscular junction(GO:0031594) |
0.0 | 2.3 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
0.0 | 0.5 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
0.0 | 0.6 | GO:0031091 | platelet alpha granule(GO:0031091) |
0.0 | 4.6 | GO:0005923 | bicellular tight junction(GO:0005923) |
0.0 | 0.7 | GO:0042588 | zymogen granule(GO:0042588) |
0.0 | 0.7 | GO:0045095 | keratin filament(GO:0045095) |
0.0 | 0.2 | GO:0035068 | micro-ribonucleoprotein complex(GO:0035068) |
0.0 | 1.6 | GO:0000786 | nucleosome(GO:0000786) |
0.0 | 0.5 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
0.0 | 0.3 | GO:0000346 | transcription export complex(GO:0000346) |
0.0 | 0.3 | GO:0005839 | proteasome core complex(GO:0005839) |
0.0 | 0.5 | GO:0043034 | costamere(GO:0043034) |
0.0 | 0.6 | GO:0032391 | photoreceptor connecting cilium(GO:0032391) |
0.0 | 0.5 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.4 | 4.2 | GO:0035373 | chondroitin sulfate proteoglycan binding(GO:0035373) |
1.2 | 4.7 | GO:0004945 | angiotensin type II receptor activity(GO:0004945) |
0.4 | 1.6 | GO:0052798 | beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798) |
0.4 | 1.1 | GO:0016748 | succinyltransferase activity(GO:0016748) |
0.3 | 1.6 | GO:0034988 | Fc-gamma receptor I complex binding(GO:0034988) |
0.2 | 1.7 | GO:0005499 | vitamin D binding(GO:0005499) |
0.2 | 1.5 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
0.2 | 2.1 | GO:0030274 | LIM domain binding(GO:0030274) |
0.2 | 1.4 | GO:0097322 | 7SK snRNA binding(GO:0097322) |
0.2 | 1.3 | GO:0004064 | arylesterase activity(GO:0004064) |
0.1 | 0.7 | GO:0004977 | melanocortin receptor activity(GO:0004977) |
0.1 | 1.8 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
0.1 | 0.9 | GO:0036122 | BMP binding(GO:0036122) BMP receptor activity(GO:0098821) |
0.1 | 0.5 | GO:0008321 | Ral guanyl-nucleotide exchange factor activity(GO:0008321) |
0.1 | 0.3 | GO:0016316 | phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) |
0.1 | 0.7 | GO:0047498 | calcium-dependent phospholipase A2 activity(GO:0047498) |
0.1 | 0.2 | GO:0016262 | protein N-acetylglucosaminyltransferase activity(GO:0016262) |
0.1 | 0.3 | GO:0050816 | phosphothreonine binding(GO:0050816) |
0.1 | 0.2 | GO:0005143 | interleukin-12 receptor binding(GO:0005143) |
0.1 | 0.4 | GO:0048495 | GTPase inhibitor activity(GO:0005095) Roundabout binding(GO:0048495) |
0.0 | 1.2 | GO:0003746 | translation elongation factor activity(GO:0003746) |
0.0 | 1.3 | GO:0051371 | muscle alpha-actinin binding(GO:0051371) |
0.0 | 2.5 | GO:0097472 | cyclin-dependent protein kinase activity(GO:0097472) |
0.0 | 1.9 | GO:0071837 | HMG box domain binding(GO:0071837) |
0.0 | 1.5 | GO:0070412 | R-SMAD binding(GO:0070412) |
0.0 | 0.9 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
0.0 | 0.6 | GO:0015197 | peptide transporter activity(GO:0015197) |
0.0 | 1.9 | GO:0043027 | cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) |
0.0 | 0.3 | GO:0031802 | type 5 metabotropic glutamate receptor binding(GO:0031802) |
0.0 | 15.2 | GO:0005543 | phospholipid binding(GO:0005543) |
0.0 | 1.1 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
0.0 | 4.9 | GO:0030674 | protein binding, bridging(GO:0030674) |
0.0 | 0.4 | GO:0046625 | sphingolipid binding(GO:0046625) |
0.0 | 0.2 | GO:0019870 | potassium channel inhibitor activity(GO:0019870) |
0.0 | 1.1 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
0.0 | 3.1 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
0.0 | 1.1 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
0.0 | 0.6 | GO:0097602 | cullin family protein binding(GO:0097602) |
0.0 | 1.0 | GO:0046875 | ephrin receptor binding(GO:0046875) |
0.0 | 0.5 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
0.0 | 4.0 | GO:0017124 | SH3 domain binding(GO:0017124) |
0.0 | 1.1 | GO:0008028 | monocarboxylic acid transmembrane transporter activity(GO:0008028) |
0.0 | 0.5 | GO:0004383 | guanylate cyclase activity(GO:0004383) |
0.0 | 0.5 | GO:0019706 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707) |
0.0 | 0.3 | GO:0004535 | poly(A)-specific ribonuclease activity(GO:0004535) |
0.0 | 1.1 | GO:0005518 | collagen binding(GO:0005518) |
0.0 | 0.2 | GO:0038036 | sphingosine-1-phosphate receptor activity(GO:0038036) |
0.0 | 0.6 | GO:0004601 | peroxidase activity(GO:0004601) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 4.2 | PID SYNDECAN 3 PATHWAY | Syndecan-3-mediated signaling events |
0.1 | 2.3 | SA REG CASCADE OF CYCLIN EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
0.1 | 6.1 | PID INTEGRIN A4B1 PATHWAY | Alpha4 beta1 integrin signaling events |
0.1 | 2.8 | ST ERK1 ERK2 MAPK PATHWAY | ERK1/ERK2 MAPK Pathway |
0.0 | 1.6 | PID WNT NONCANONICAL PATHWAY | Noncanonical Wnt signaling pathway |
0.0 | 1.0 | PID EPHB FWD PATHWAY | EPHB forward signaling |
0.0 | 0.9 | PID FAK PATHWAY | Signaling events mediated by focal adhesion kinase |
0.0 | 1.8 | PID FCER1 PATHWAY | Fc-epsilon receptor I signaling in mast cells |
0.0 | 1.5 | PID ERBB1 INTERNALIZATION PATHWAY | Internalization of ErbB1 |
0.0 | 0.8 | PID P38 MK2 PATHWAY | p38 signaling mediated by MAPKAP kinases |
0.0 | 1.5 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
0.0 | 0.9 | PID BMP PATHWAY | BMP receptor signaling |
0.0 | 3.4 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
0.0 | 0.4 | PID ALPHA SYNUCLEIN PATHWAY | Alpha-synuclein signaling |
0.0 | 0.3 | PID MYC PATHWAY | C-MYC pathway |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 2.3 | REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION | Genes involved in Cyclin A/B1 associated events during G2/M transition |
0.1 | 1.8 | REACTOME KINESINS | Genes involved in Kinesins |
0.1 | 1.6 | REACTOME PRE NOTCH PROCESSING IN GOLGI | Genes involved in Pre-NOTCH Processing in Golgi |
0.1 | 1.4 | REACTOME METABOLISM OF PORPHYRINS | Genes involved in Metabolism of porphyrins |
0.1 | 1.9 | REACTOME ERK MAPK TARGETS | Genes involved in ERK/MAPK targets |
0.1 | 1.1 | REACTOME FGFR1 LIGAND BINDING AND ACTIVATION | Genes involved in FGFR1 ligand binding and activation |
0.0 | 1.3 | REACTOME LYSOSOME VESICLE BIOGENESIS | Genes involved in Lysosome Vesicle Biogenesis |
0.0 | 2.9 | REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
0.0 | 0.7 | REACTOME PLATELET SENSITIZATION BY LDL | Genes involved in Platelet sensitization by LDL |
0.0 | 0.6 | REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION | Genes involved in Apoptosis induced DNA fragmentation |
0.0 | 1.5 | REACTOME EGFR DOWNREGULATION | Genes involved in EGFR downregulation |
0.0 | 6.0 | REACTOME PEPTIDE LIGAND BINDING RECEPTORS | Genes involved in Peptide ligand-binding receptors |
0.0 | 0.4 | REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS | Genes involved in NRIF signals cell death from the nucleus |
0.0 | 0.4 | REACTOME ACTIVATION OF RAC | Genes involved in Activation of Rac |
0.0 | 0.7 | REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS | Genes involved in Transport of Ribonucleoproteins into the Host Nucleus |
0.0 | 1.1 | REACTOME RNA POL I PROMOTER OPENING | Genes involved in RNA Polymerase I Promoter Opening |
0.0 | 0.6 | REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER | Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter |
0.0 | 0.5 | REACTOME ENOS ACTIVATION AND REGULATION | Genes involved in eNOS activation and regulation |
0.0 | 0.3 | REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE | Genes involved in Synthesis of PIPs at the early endosome membrane |
0.0 | 0.9 | REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS | Genes involved in Apoptotic cleavage of cellular proteins |
0.0 | 0.4 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
0.0 | 2.2 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |