avrg: GSE58827: Dynamics of the Mouse Liver
Gene Symbol | Gene ID | Gene Info |
---|---|---|
Nr2c1
|
ENSMUSG00000005897.8 | nuclear receptor subfamily 2, group C, member 1 |
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Nr2c1 | mm10_v2_chr10_+_94147982_94148023 | 0.03 | 8.8e-01 | Click! |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.6 | 1.8 | GO:0010710 | regulation of collagen catabolic process(GO:0010710) negative regulation of extracellular matrix disassembly(GO:0010716) |
0.6 | 6.1 | GO:0030240 | skeletal muscle thin filament assembly(GO:0030240) |
0.5 | 1.4 | GO:2000097 | regulation of smooth muscle cell-matrix adhesion(GO:2000097) |
0.4 | 1.2 | GO:0010133 | proline catabolic process to glutamate(GO:0010133) |
0.4 | 1.2 | GO:0045204 | MAPK export from nucleus(GO:0045204) |
0.4 | 3.4 | GO:0032264 | IMP salvage(GO:0032264) |
0.3 | 1.4 | GO:0014846 | esophagus smooth muscle contraction(GO:0014846) |
0.3 | 1.6 | GO:0015793 | glycerol transport(GO:0015793) renal water absorption(GO:0070295) |
0.3 | 1.8 | GO:0045110 | intermediate filament bundle assembly(GO:0045110) |
0.2 | 1.1 | GO:0060578 | subthalamic nucleus development(GO:0021763) superior vena cava morphogenesis(GO:0060578) |
0.2 | 2.1 | GO:0098935 | dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937) |
0.2 | 4.2 | GO:0031115 | negative regulation of microtubule polymerization(GO:0031115) |
0.2 | 1.3 | GO:1904923 | negative regulation of macromitophagy(GO:1901525) regulation of mitophagy in response to mitochondrial depolarization(GO:1904923) |
0.2 | 3.9 | GO:0048172 | regulation of short-term neuronal synaptic plasticity(GO:0048172) |
0.2 | 0.5 | GO:0009173 | UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049) |
0.2 | 0.8 | GO:0060313 | negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313) |
0.1 | 0.5 | GO:0000415 | negative regulation of histone H3-K36 methylation(GO:0000415) |
0.1 | 0.7 | GO:0001830 | trophectodermal cell fate commitment(GO:0001830) |
0.1 | 0.7 | GO:1990928 | response to amino acid starvation(GO:1990928) |
0.1 | 0.4 | GO:0003365 | establishment of cell polarity involved in ameboidal cell migration(GO:0003365) |
0.1 | 2.1 | GO:0032060 | bleb assembly(GO:0032060) |
0.1 | 0.9 | GO:0032286 | central nervous system myelin maintenance(GO:0032286) |
0.1 | 0.5 | GO:0032485 | regulation of Ral protein signal transduction(GO:0032485) |
0.1 | 0.4 | GO:0061295 | regulation of pronephros size(GO:0035565) mesonephros morphogenesis(GO:0061206) mesonephric nephron development(GO:0061215) mesonephric nephron morphogenesis(GO:0061228) mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis(GO:0061235) regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061295) negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061296) mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:1901146) |
0.1 | 1.5 | GO:0006744 | ubiquinone biosynthetic process(GO:0006744) |
0.1 | 0.8 | GO:0080009 | mRNA methylation(GO:0080009) |
0.1 | 0.8 | GO:0090527 | actin filament reorganization(GO:0090527) |
0.1 | 1.1 | GO:0051574 | positive regulation of histone H3-K9 methylation(GO:0051574) |
0.1 | 0.8 | GO:0035871 | protein K11-linked deubiquitination(GO:0035871) |
0.1 | 0.7 | GO:0019372 | lipoxygenase pathway(GO:0019372) |
0.1 | 0.5 | GO:0045196 | establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200) |
0.1 | 0.8 | GO:0075522 | IRES-dependent viral translational initiation(GO:0075522) |
0.1 | 0.5 | GO:0042760 | very long-chain fatty acid catabolic process(GO:0042760) |
0.1 | 0.3 | GO:0018343 | protein farnesylation(GO:0018343) |
0.1 | 0.5 | GO:0045084 | positive regulation of interleukin-12 biosynthetic process(GO:0045084) |
0.0 | 0.1 | GO:0014873 | response to muscle activity involved in regulation of muscle adaptation(GO:0014873) |
0.0 | 1.2 | GO:0097094 | craniofacial suture morphogenesis(GO:0097094) |
0.0 | 0.3 | GO:1990481 | mRNA pseudouridine synthesis(GO:1990481) |
0.0 | 0.9 | GO:0060218 | hematopoietic stem cell differentiation(GO:0060218) |
0.0 | 0.2 | GO:0035359 | negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359) monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522) |
0.0 | 0.8 | GO:0007095 | mitotic G2 DNA damage checkpoint(GO:0007095) |
0.0 | 0.7 | GO:0043374 | CD8-positive, alpha-beta T cell differentiation(GO:0043374) |
0.0 | 0.9 | GO:0030033 | microvillus assembly(GO:0030033) |
0.0 | 0.6 | GO:0045899 | positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899) |
0.0 | 0.3 | GO:0015879 | carnitine transport(GO:0015879) |
0.0 | 0.5 | GO:0048096 | chromatin-mediated maintenance of transcription(GO:0048096) |
0.0 | 0.8 | GO:0000289 | nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289) |
0.0 | 0.8 | GO:0048268 | clathrin coat assembly(GO:0048268) |
0.0 | 2.2 | GO:0015909 | long-chain fatty acid transport(GO:0015909) |
0.0 | 0.1 | GO:1900149 | positive regulation of Schwann cell migration(GO:1900149) |
0.0 | 0.6 | GO:0001553 | luteinization(GO:0001553) |
0.0 | 1.2 | GO:0050919 | negative chemotaxis(GO:0050919) |
0.0 | 0.3 | GO:0090110 | cargo loading into COPII-coated vesicle(GO:0090110) |
0.0 | 0.5 | GO:0071803 | positive regulation of podosome assembly(GO:0071803) |
0.0 | 0.4 | GO:0045199 | maintenance of epithelial cell apical/basal polarity(GO:0045199) |
0.0 | 0.0 | GO:0090403 | oxidative stress-induced premature senescence(GO:0090403) |
0.0 | 0.8 | GO:0000387 | spliceosomal snRNP assembly(GO:0000387) |
0.0 | 0.2 | GO:0071044 | histone mRNA catabolic process(GO:0071044) |
0.0 | 0.5 | GO:0048025 | negative regulation of mRNA splicing, via spliceosome(GO:0048025) |
0.0 | 0.6 | GO:0043001 | Golgi to plasma membrane protein transport(GO:0043001) |
0.0 | 0.1 | GO:0070601 | centromeric sister chromatid cohesion(GO:0070601) |
0.0 | 0.1 | GO:1900364 | negative regulation of mRNA 3'-end processing(GO:0031441) negative regulation of mRNA polyadenylation(GO:1900364) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 1.4 | GO:0042583 | chromaffin granule(GO:0042583) |
0.2 | 1.8 | GO:0071438 | invadopodium membrane(GO:0071438) |
0.2 | 0.8 | GO:0036396 | MIS complex(GO:0036396) |
0.2 | 0.8 | GO:0034715 | U7 snRNP(GO:0005683) pICln-Sm protein complex(GO:0034715) |
0.1 | 5.2 | GO:0005865 | striated muscle thin filament(GO:0005865) |
0.1 | 0.8 | GO:0071541 | eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541) |
0.1 | 1.3 | GO:0035631 | CD40 receptor complex(GO:0035631) |
0.1 | 0.7 | GO:0005850 | eukaryotic translation initiation factor 2 complex(GO:0005850) |
0.1 | 1.8 | GO:0045095 | keratin filament(GO:0045095) |
0.0 | 0.4 | GO:0061574 | ASAP complex(GO:0061574) |
0.0 | 0.9 | GO:0017146 | NMDA selective glutamate receptor complex(GO:0017146) |
0.0 | 1.1 | GO:0071565 | nBAF complex(GO:0071565) |
0.0 | 4.6 | GO:0031594 | neuromuscular junction(GO:0031594) |
0.0 | 4.2 | GO:0043198 | dendritic shaft(GO:0043198) |
0.0 | 1.1 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
0.0 | 0.2 | GO:0000308 | cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308) |
0.0 | 1.1 | GO:0032839 | dendrite cytoplasm(GO:0032839) |
0.0 | 0.1 | GO:0072534 | perineuronal net(GO:0072534) |
0.0 | 0.1 | GO:0032021 | NELF complex(GO:0032021) |
0.0 | 4.7 | GO:0005903 | brush border(GO:0005903) |
0.0 | 0.4 | GO:0005686 | U2 snRNP(GO:0005686) |
0.0 | 0.3 | GO:0030127 | COPII vesicle coat(GO:0030127) |
0.0 | 3.8 | GO:0005741 | mitochondrial outer membrane(GO:0005741) |
0.0 | 0.8 | GO:0030131 | clathrin adaptor complex(GO:0030131) |
0.0 | 0.5 | GO:0001891 | phagocytic cup(GO:0001891) |
0.0 | 0.7 | GO:0031519 | PcG protein complex(GO:0031519) |
0.0 | 0.7 | GO:0005720 | nuclear heterochromatin(GO:0005720) |
0.0 | 0.5 | GO:0005721 | pericentric heterochromatin(GO:0005721) |
0.0 | 1.2 | GO:0030864 | cortical actin cytoskeleton(GO:0030864) |
0.0 | 0.5 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
0.0 | 5.7 | GO:0005667 | transcription factor complex(GO:0005667) |
0.0 | 0.4 | GO:0008180 | COP9 signalosome(GO:0008180) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.4 | 4.2 | GO:0052658 | inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) |
0.8 | 4.2 | GO:0004095 | carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416) |
0.4 | 1.5 | GO:0050347 | trans-hexaprenyltranstransferase activity(GO:0000010) trans-octaprenyltranstransferase activity(GO:0050347) |
0.4 | 3.4 | GO:0047623 | AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623) |
0.4 | 1.8 | GO:1990254 | keratin filament binding(GO:1990254) |
0.3 | 1.6 | GO:0015254 | glycerol channel activity(GO:0015254) |
0.3 | 1.4 | GO:0008449 | N-acetylglucosamine-6-sulfatase activity(GO:0008449) |
0.2 | 0.9 | GO:0051373 | FATZ binding(GO:0051373) |
0.2 | 1.8 | GO:0008239 | dipeptidyl-peptidase activity(GO:0008239) |
0.1 | 2.1 | GO:0050811 | GABA receptor binding(GO:0050811) |
0.1 | 0.5 | GO:0004849 | uridine kinase activity(GO:0004849) |
0.1 | 0.8 | GO:0008889 | glycerophosphodiester phosphodiesterase activity(GO:0008889) |
0.1 | 1.0 | GO:0005225 | volume-sensitive anion channel activity(GO:0005225) |
0.1 | 0.9 | GO:0017151 | DEAD/H-box RNA helicase binding(GO:0017151) |
0.1 | 1.2 | GO:0032036 | myosin heavy chain binding(GO:0032036) |
0.1 | 0.3 | GO:0005124 | scavenger receptor binding(GO:0005124) |
0.0 | 0.3 | GO:0004311 | farnesyltranstransferase activity(GO:0004311) |
0.0 | 1.2 | GO:0071949 | FAD binding(GO:0071949) |
0.0 | 0.8 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
0.0 | 0.5 | GO:1990825 | sequence-specific mRNA binding(GO:1990825) |
0.0 | 0.1 | GO:0016971 | flavin-linked sulfhydryl oxidase activity(GO:0016971) |
0.0 | 0.8 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
0.0 | 1.1 | GO:0032452 | histone demethylase activity(GO:0032452) |
0.0 | 0.2 | GO:0004652 | polynucleotide adenylyltransferase activity(GO:0004652) |
0.0 | 1.4 | GO:0003743 | translation initiation factor activity(GO:0003743) |
0.0 | 0.2 | GO:0008526 | phosphatidylinositol transporter activity(GO:0008526) |
0.0 | 0.5 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
0.0 | 0.6 | GO:0017025 | TBP-class protein binding(GO:0017025) |
0.0 | 1.0 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
0.0 | 0.3 | GO:0009982 | pseudouridine synthase activity(GO:0009982) |
0.0 | 0.9 | GO:0001540 | beta-amyloid binding(GO:0001540) |
0.0 | 0.5 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
0.0 | 1.4 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 5.2 | PID RHOA PATHWAY | RhoA signaling pathway |
0.0 | 3.3 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
0.0 | 2.5 | SIG CHEMOTAXIS | Genes related to chemotaxis |
0.0 | 1.8 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
0.0 | 1.4 | PID UPA UPAR PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
0.0 | 0.8 | PID P38 MKK3 6PATHWAY | p38 MAPK signaling pathway |
0.0 | 0.8 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
0.0 | 0.7 | PID CERAMIDE PATHWAY | Ceramide signaling pathway |
0.0 | 2.4 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
0.0 | 0.8 | PID RAC1 REG PATHWAY | Regulation of RAC1 activity |
0.0 | 0.7 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 3.4 | REACTOME PURINE SALVAGE | Genes involved in Purine salvage |
0.1 | 1.6 | REACTOME PASSIVE TRANSPORT BY AQUAPORINS | Genes involved in Passive Transport by Aquaporins |
0.1 | 3.5 | REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE | Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle |
0.1 | 4.2 | REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE | Genes involved in Synthesis of PIPs at the plasma membrane |
0.1 | 0.8 | REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS | Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs |
0.1 | 0.8 | REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION | Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression |
0.1 | 0.8 | REACTOME ACTIVATION OF RAC | Genes involved in Activation of Rac |
0.0 | 1.4 | REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION | Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription |
0.0 | 0.8 | REACTOME DEADENYLATION OF MRNA | Genes involved in Deadenylation of mRNA |
0.0 | 1.3 | REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
0.0 | 0.3 | REACTOME PROSTANOID LIGAND RECEPTORS | Genes involved in Prostanoid ligand receptors |
0.0 | 0.9 | REACTOME STRIATED MUSCLE CONTRACTION | Genes involved in Striated Muscle Contraction |
0.0 | 0.7 | REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION | Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression |
0.0 | 0.4 | REACTOME SIGNALING BY HIPPO | Genes involved in Signaling by Hippo |
0.0 | 0.5 | REACTOME PYRIMIDINE METABOLISM | Genes involved in Pyrimidine metabolism |
0.0 | 0.5 | REACTOME MRNA 3 END PROCESSING | Genes involved in mRNA 3'-end processing |