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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Sox30

Z-value: 1.10

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Transcription factors associated with Sox30

Gene Symbol Gene ID Gene Info
ENSMUSG00000040489.5 SRY (sex determining region Y)-box 30

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Sox30mm10_v2_chr11_+_45980309_459803370.401.5e-02Click!

Activity profile of Sox30 motif

Sorted Z-values of Sox30 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Sox30

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 4.3 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
0.6 1.7 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.2 2.2 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.2 5.2 GO:0097435 fibril organization(GO:0097435)
0.1 2.5 GO:0070307 lens fiber cell development(GO:0070307)
0.1 0.8 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.3 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.1 2.0 GO:0014823 response to activity(GO:0014823)
0.0 2.4 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.0 0.1 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.0 0.8 GO:0008272 sulfate transport(GO:0008272)
0.0 2.0 GO:0001541 ovarian follicle development(GO:0001541)
0.0 1.6 GO:0030819 positive regulation of cyclic nucleotide biosynthetic process(GO:0030804) positive regulation of cAMP biosynthetic process(GO:0030819)
0.0 5.9 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 1.0 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.7 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.0 0.3 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.2 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.3 GO:0046321 positive regulation of fatty acid oxidation(GO:0046321)
0.0 0.1 GO:0044821 nuclear matrix organization(GO:0043578) meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) nuclear matrix anchoring at nuclear membrane(GO:0090292) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 0.3 GO:0003351 epithelial cilium movement(GO:0003351)
0.0 0.3 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.1 GO:0038203 TORC2 signaling(GO:0038203)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 5.8 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.3 1.7 GO:0042583 chromaffin granule(GO:0042583)
0.1 1.0 GO:0001739 sex chromatin(GO:0001739)
0.1 2.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 1.2 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 1.6 GO:0031430 M band(GO:0031430)
0.0 3.6 GO:0005882 intermediate filament(GO:0005882)
0.0 0.5 GO:0032982 myosin filament(GO:0032982)
0.0 2.6 GO:0031225 anchored component of membrane(GO:0031225)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 17.3 GO:0004556 alpha-amylase activity(GO:0004556)
1.3 5.0 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.5 2.2 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733)
0.4 2.0 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.3 4.3 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.3 1.6 GO:0004977 melanocortin receptor activity(GO:0004977)
0.1 2.4 GO:0015643 toxic substance binding(GO:0015643)
0.1 2.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 1.3 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 2.9 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.1 0.3 GO:0032896 palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.1 1.6 GO:0005523 tropomyosin binding(GO:0005523)
0.1 0.2 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 7.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.8 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 0.3 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.0 0.6 GO:0070330 aromatase activity(GO:0070330)
0.0 0.3 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 1.2 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 1.8 GO:0019905 syntaxin binding(GO:0019905)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 4.8 PID NOTCH PATHWAY Notch signaling pathway
0.0 1.7 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 5.3 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 3.2 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.3 PID SHP2 PATHWAY SHP2 signaling
0.0 0.6 PID ARF6 PATHWAY Arf6 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.9 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.1 1.3 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 2.0 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.1 0.9 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 2.2 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 1.7 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.2 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling