avrg: GSE58827: Dynamics of the Mouse Liver
Gene Symbol | Gene ID | Gene Info |
---|---|---|
Nr4a2
|
ENSMUSG00000026826.7 | nuclear receptor subfamily 4, group A, member 2 |
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Nr4a2 | mm10_v2_chr2_-_57113053_57113072 | -0.20 | 2.5e-01 | Click! |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 1.2 | GO:0021933 | radial glia guided migration of cerebellar granule cell(GO:0021933) |
0.3 | 1.7 | GO:0032915 | positive regulation of transforming growth factor beta2 production(GO:0032915) |
0.3 | 1.2 | GO:2000158 | positive regulation of ubiquitin-specific protease activity(GO:2000158) |
0.2 | 2.5 | GO:0016554 | cytidine to uridine editing(GO:0016554) |
0.2 | 3.2 | GO:0015747 | urate transport(GO:0015747) |
0.2 | 0.9 | GO:0050787 | detoxification of mercury ion(GO:0050787) |
0.2 | 0.7 | GO:0071929 | alpha-tubulin acetylation(GO:0071929) |
0.2 | 3.2 | GO:0036158 | outer dynein arm assembly(GO:0036158) |
0.1 | 0.7 | GO:0032304 | negative regulation of icosanoid secretion(GO:0032304) |
0.1 | 0.7 | GO:0021905 | pancreatic A cell development(GO:0003322) forebrain-midbrain boundary formation(GO:0021905) somatic motor neuron fate commitment(GO:0021917) regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment(GO:0021918) sensory neuron migration(GO:1904937) |
0.1 | 1.0 | GO:0009313 | ganglioside catabolic process(GO:0006689) oligosaccharide catabolic process(GO:0009313) |
0.1 | 0.5 | GO:0036367 | adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367) |
0.1 | 0.5 | GO:0051562 | negative regulation of mitochondrial calcium ion concentration(GO:0051562) |
0.1 | 1.7 | GO:2001256 | regulation of store-operated calcium entry(GO:2001256) |
0.1 | 0.4 | GO:0003104 | positive regulation of glomerular filtration(GO:0003104) |
0.1 | 0.9 | GO:0035021 | negative regulation of Rac protein signal transduction(GO:0035021) |
0.1 | 0.3 | GO:0019405 | alditol catabolic process(GO:0019405) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166) |
0.1 | 0.3 | GO:0035964 | COPI-coated vesicle budding(GO:0035964) protein localization to endoplasmic reticulum exit site(GO:0070973) |
0.1 | 0.7 | GO:2000253 | positive regulation of feeding behavior(GO:2000253) |
0.1 | 0.7 | GO:0030718 | germ-line stem cell population maintenance(GO:0030718) |
0.1 | 1.5 | GO:0036295 | cellular response to increased oxygen levels(GO:0036295) |
0.1 | 0.2 | GO:0060382 | release from viral latency(GO:0019046) regulation of DNA strand elongation(GO:0060382) |
0.1 | 0.7 | GO:0086023 | adrenergic receptor signaling pathway involved in heart process(GO:0086023) |
0.1 | 0.4 | GO:0070672 | response to interleukin-15(GO:0070672) |
0.1 | 0.6 | GO:0090400 | stress-induced premature senescence(GO:0090400) |
0.1 | 0.8 | GO:0070842 | aggresome assembly(GO:0070842) |
0.1 | 0.5 | GO:0006685 | sphingomyelin catabolic process(GO:0006685) |
0.1 | 0.4 | GO:1903378 | positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378) |
0.1 | 0.2 | GO:0002465 | CD4-positive, CD25-positive, alpha-beta regulatory T cell lineage commitment(GO:0002362) peripheral T cell tolerance induction(GO:0002458) peripheral tolerance induction(GO:0002465) negative regulation of histone deacetylation(GO:0031064) negative regulation of interferon-gamma biosynthetic process(GO:0045077) |
0.1 | 0.3 | GO:0030920 | N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920) |
0.1 | 0.5 | GO:0070601 | centromeric sister chromatid cohesion(GO:0070601) |
0.1 | 2.1 | GO:1901522 | positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522) |
0.1 | 0.7 | GO:0098719 | sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118) |
0.1 | 0.4 | GO:0098728 | germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728) |
0.0 | 0.6 | GO:0051454 | pH elevation(GO:0045852) intracellular pH elevation(GO:0051454) |
0.0 | 0.6 | GO:0002862 | negative regulation of inflammatory response to antigenic stimulus(GO:0002862) |
0.0 | 0.6 | GO:0010839 | negative regulation of keratinocyte proliferation(GO:0010839) |
0.0 | 0.3 | GO:0006627 | protein processing involved in protein targeting to mitochondrion(GO:0006627) |
0.0 | 0.5 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
0.0 | 0.3 | GO:0048386 | positive regulation of retinoic acid receptor signaling pathway(GO:0048386) |
0.0 | 0.3 | GO:0019388 | galactose catabolic process(GO:0019388) |
0.0 | 0.3 | GO:0031642 | negative regulation of myelination(GO:0031642) |
0.0 | 0.2 | GO:1902510 | regulation of apoptotic DNA fragmentation(GO:1902510) |
0.0 | 0.2 | GO:0008065 | establishment of blood-nerve barrier(GO:0008065) |
0.0 | 0.1 | GO:0051835 | positive regulation of synapse structural plasticity(GO:0051835) |
0.0 | 0.7 | GO:0010918 | positive regulation of mitochondrial membrane potential(GO:0010918) |
0.0 | 0.8 | GO:0007602 | phototransduction(GO:0007602) |
0.0 | 0.7 | GO:2000310 | regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310) |
0.0 | 0.2 | GO:0019243 | methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727) |
0.0 | 0.4 | GO:1900119 | positive regulation of execution phase of apoptosis(GO:1900119) |
0.0 | 0.3 | GO:0033601 | positive regulation of mammary gland epithelial cell proliferation(GO:0033601) |
0.0 | 0.3 | GO:0021520 | spinal cord motor neuron cell fate specification(GO:0021520) |
0.0 | 1.4 | GO:0046847 | filopodium assembly(GO:0046847) |
0.0 | 0.1 | GO:0061002 | negative regulation of dendritic spine morphogenesis(GO:0061002) |
0.0 | 0.3 | GO:0007625 | grooming behavior(GO:0007625) |
0.0 | 0.1 | GO:0032625 | interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619) |
0.0 | 0.1 | GO:0034382 | chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830) |
0.0 | 0.6 | GO:0050892 | intestinal absorption(GO:0050892) |
0.0 | 0.8 | GO:0045668 | negative regulation of osteoblast differentiation(GO:0045668) |
0.0 | 0.4 | GO:0031424 | keratinization(GO:0031424) |
0.0 | 0.3 | GO:0006308 | DNA catabolic process(GO:0006308) |
0.0 | 0.1 | GO:0060591 | chondroblast differentiation(GO:0060591) |
0.0 | 0.8 | GO:0051341 | regulation of oxidoreductase activity(GO:0051341) |
0.0 | 0.4 | GO:0032467 | positive regulation of cytokinesis(GO:0032467) |
0.0 | 0.1 | GO:1900383 | regulation of synaptic plasticity by receptor localization to synapse(GO:1900383) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 1.5 | GO:0033180 | proton-transporting V-type ATPase, V1 domain(GO:0033180) |
0.1 | 0.5 | GO:0030868 | smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425) |
0.1 | 0.9 | GO:0031415 | NatA complex(GO:0031415) |
0.1 | 0.4 | GO:1990452 | Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452) |
0.1 | 0.7 | GO:0044233 | ER-mitochondrion membrane contact site(GO:0044233) |
0.1 | 0.7 | GO:0097427 | microtubule bundle(GO:0097427) |
0.0 | 0.7 | GO:0030122 | AP-2 adaptor complex(GO:0030122) |
0.0 | 1.7 | GO:0035861 | site of double-strand break(GO:0035861) |
0.0 | 0.6 | GO:0045179 | apical cortex(GO:0045179) |
0.0 | 1.8 | GO:0043034 | costamere(GO:0043034) |
0.0 | 0.6 | GO:0032156 | septin cytoskeleton(GO:0032156) |
0.0 | 0.3 | GO:0019907 | cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907) |
0.0 | 0.4 | GO:0046581 | intercellular canaliculus(GO:0046581) |
0.0 | 0.5 | GO:0042599 | lamellar body(GO:0042599) |
0.0 | 3.2 | GO:0005814 | centriole(GO:0005814) |
0.0 | 0.3 | GO:0005750 | mitochondrial respiratory chain complex III(GO:0005750) |
0.0 | 0.6 | GO:0097225 | sperm midpiece(GO:0097225) |
0.0 | 0.5 | GO:0030056 | hemidesmosome(GO:0030056) |
0.0 | 0.5 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
0.0 | 1.0 | GO:0030964 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
0.0 | 0.8 | GO:0001917 | photoreceptor inner segment(GO:0001917) |
0.0 | 0.8 | GO:0016235 | aggresome(GO:0016235) |
0.0 | 0.4 | GO:0030057 | desmosome(GO:0030057) |
0.0 | 0.4 | GO:0001533 | cornified envelope(GO:0001533) |
0.0 | 0.2 | GO:0061702 | inflammasome complex(GO:0061702) |
0.0 | 1.0 | GO:0005811 | lipid particle(GO:0005811) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 1.2 | GO:0035800 | deubiquitinase activator activity(GO:0035800) |
0.2 | 2.1 | GO:0004886 | 9-cis retinoic acid receptor activity(GO:0004886) |
0.2 | 3.2 | GO:0015143 | urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702) |
0.2 | 1.0 | GO:0004308 | exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796) |
0.2 | 0.5 | GO:0036470 | tyrosine 3-monooxygenase activator activity(GO:0036470) L-dopa decarboxylase activator activity(GO:0036478) |
0.2 | 1.8 | GO:0031802 | type 5 metabotropic glutamate receptor binding(GO:0031802) |
0.2 | 1.7 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
0.1 | 0.5 | GO:0072320 | volume-sensitive chloride channel activity(GO:0072320) |
0.1 | 0.7 | GO:0042030 | ATPase inhibitor activity(GO:0042030) |
0.1 | 0.7 | GO:0004468 | lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468) |
0.1 | 0.6 | GO:0001515 | opioid peptide activity(GO:0001515) |
0.1 | 0.6 | GO:0005324 | long-chain fatty acid transporter activity(GO:0005324) |
0.1 | 0.4 | GO:0050816 | phosphothreonine binding(GO:0050816) |
0.1 | 0.3 | GO:0043812 | phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812) |
0.1 | 0.7 | GO:0015386 | potassium:proton antiporter activity(GO:0015386) |
0.1 | 0.6 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
0.1 | 0.3 | GO:1990190 | peptide-glutamate-N-acetyltransferase activity(GO:1990190) |
0.1 | 0.5 | GO:0004767 | sphingomyelin phosphodiesterase activity(GO:0004767) |
0.1 | 1.5 | GO:0046961 | proton-transporting ATPase activity, rotational mechanism(GO:0046961) |
0.1 | 0.7 | GO:0031957 | very long-chain fatty acid-CoA ligase activity(GO:0031957) |
0.1 | 0.6 | GO:0008239 | dipeptidyl-peptidase activity(GO:0008239) |
0.1 | 0.5 | GO:0004596 | peptide alpha-N-acetyltransferase activity(GO:0004596) |
0.0 | 0.5 | GO:0008429 | phosphatidylethanolamine binding(GO:0008429) |
0.0 | 0.2 | GO:0016649 | electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649) |
0.0 | 0.7 | GO:0003680 | AT DNA binding(GO:0003680) |
0.0 | 0.2 | GO:0017040 | ceramidase activity(GO:0017040) |
0.0 | 0.3 | GO:0004614 | phosphoglucomutase activity(GO:0004614) |
0.0 | 0.6 | GO:0019531 | oxalate transmembrane transporter activity(GO:0019531) |
0.0 | 0.7 | GO:0032454 | histone demethylase activity (H3-K9 specific)(GO:0032454) |
0.0 | 0.4 | GO:0030296 | protein tyrosine kinase activator activity(GO:0030296) |
0.0 | 0.6 | GO:0045295 | gamma-catenin binding(GO:0045295) |
0.0 | 0.3 | GO:0016861 | intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861) |
0.0 | 0.2 | GO:0005000 | vasopressin receptor activity(GO:0005000) |
0.0 | 0.2 | GO:0004865 | protein serine/threonine phosphatase inhibitor activity(GO:0004865) |
0.0 | 0.2 | GO:0004416 | hydroxyacylglutathione hydrolase activity(GO:0004416) |
0.0 | 0.1 | GO:0016971 | flavin-linked sulfhydryl oxidase activity(GO:0016971) |
0.0 | 0.3 | GO:0035014 | phosphatidylinositol 3-kinase regulator activity(GO:0035014) |
0.0 | 0.1 | GO:0008970 | phosphatidylcholine 1-acylhydrolase activity(GO:0008970) |
0.0 | 0.6 | GO:0004115 | 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) |
0.0 | 0.2 | GO:0051525 | NFAT protein binding(GO:0051525) |
0.0 | 0.4 | GO:0008137 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
0.0 | 0.9 | GO:0030507 | spectrin binding(GO:0030507) |
0.0 | 0.5 | GO:0030506 | ankyrin binding(GO:0030506) |
0.0 | 0.8 | GO:0016651 | oxidoreductase activity, acting on NAD(P)H(GO:0016651) |
0.0 | 0.4 | GO:0035259 | glucocorticoid receptor binding(GO:0035259) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 1.3 | ST G ALPHA S PATHWAY | G alpha s Pathway |
0.0 | 1.7 | SA B CELL RECEPTOR COMPLEXES | Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases. |
0.0 | 2.1 | PID RXR VDR PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
0.0 | 0.8 | PID RHODOPSIN PATHWAY | Visual signal transduction: Rods |
0.0 | 1.1 | PID NETRIN PATHWAY | Netrin-mediated signaling events |
0.0 | 0.4 | PID IL5 PATHWAY | IL5-mediated signaling events |
0.0 | 0.6 | SIG CD40PATHWAYMAP | Genes related to CD40 signaling |
0.0 | 0.5 | PID TRAIL PATHWAY | TRAIL signaling pathway |
0.0 | 0.5 | PID ALPHA SYNUCLEIN PATHWAY | Alpha-synuclein signaling |
0.0 | 0.8 | PID NFAT TFPATHWAY | Calcineurin-regulated NFAT-dependent transcription in lymphocytes |
0.0 | 0.7 | PID RHOA PATHWAY | RhoA signaling pathway |
0.0 | 1.3 | PID REG GR PATHWAY | Glucocorticoid receptor regulatory network |
0.0 | 0.7 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
0.0 | 0.5 | PID ATF2 PATHWAY | ATF-2 transcription factor network |
0.0 | 0.1 | PID INSULIN GLUCOSE PATHWAY | Insulin-mediated glucose transport |
0.0 | 0.7 | PID CDC42 PATHWAY | CDC42 signaling events |
0.0 | 0.3 | PID ARF 3PATHWAY | Arf1 pathway |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 0.8 | REACTOME OLFACTORY SIGNALING PATHWAY | Genes involved in Olfactory Signaling Pathway |
0.1 | 1.7 | REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS | Genes involved in Activation of the AP-1 family of transcription factors |
0.1 | 1.2 | REACTOME SYNTHESIS OF PE | Genes involved in Synthesis of PE |
0.1 | 1.5 | REACTOME INSULIN RECEPTOR RECYCLING | Genes involved in Insulin receptor recycling |
0.0 | 1.2 | REACTOME TRAF6 MEDIATED IRF7 ACTIVATION | Genes involved in TRAF6 mediated IRF7 activation |
0.0 | 1.3 | REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR | Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor |
0.0 | 0.1 | REACTOME ENDOSOMAL VACUOLAR PATHWAY | Genes involved in Endosomal/Vacuolar pathway |
0.0 | 1.8 | REACTOME GLYCOSPHINGOLIPID METABOLISM | Genes involved in Glycosphingolipid metabolism |
0.0 | 0.7 | REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP | Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) |
0.0 | 2.5 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
0.0 | 0.3 | REACTOME COPI MEDIATED TRANSPORT | Genes involved in COPI Mediated Transport |
0.0 | 0.7 | REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS | Genes involved in Synthesis of very long-chain fatty acyl-CoAs |
0.0 | 0.4 | REACTOME IL 7 SIGNALING | Genes involved in Interleukin-7 signaling |
0.0 | 0.3 | REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE | Genes involved in Synthesis of PIPs at the late endosome membrane |
0.0 | 0.3 | REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS | Genes involved in Glycogen breakdown (glycogenolysis) |
0.0 | 0.5 | REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS | Genes involved in Caspase-mediated cleavage of cytoskeletal proteins |
0.0 | 0.9 | REACTOME NETRIN1 SIGNALING | Genes involved in Netrin-1 signaling |
0.0 | 2.5 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
0.0 | 0.3 | REACTOME G0 AND EARLY G1 | Genes involved in G0 and Early G1 |