avrg: GSE58827: Dynamics of the Mouse Liver
Gene Symbol | Gene ID | Gene Info |
---|---|---|
Runx3
|
ENSMUSG00000070691.4 | runt related transcription factor 3 |
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Runx3 | mm10_v2_chr4_+_135120640_135120660 | 0.52 | 1.1e-03 | Click! |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.0 | 3.1 | GO:0002215 | defense response to nematode(GO:0002215) |
0.6 | 13.0 | GO:0045653 | negative regulation of megakaryocyte differentiation(GO:0045653) |
0.5 | 1.9 | GO:1900220 | semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220) |
0.4 | 1.3 | GO:0046077 | dUDP biosynthetic process(GO:0006227) pyrimidine nucleoside diphosphate metabolic process(GO:0009138) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) dUDP metabolic process(GO:0046077) |
0.4 | 2.8 | GO:0045110 | intermediate filament bundle assembly(GO:0045110) |
0.2 | 1.4 | GO:0097428 | protein maturation by iron-sulfur cluster transfer(GO:0097428) |
0.2 | 1.3 | GO:0042126 | nitrate metabolic process(GO:0042126) |
0.2 | 1.5 | GO:0051409 | response to nitrosative stress(GO:0051409) |
0.2 | 1.5 | GO:0001867 | complement activation, lectin pathway(GO:0001867) |
0.1 | 3.0 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
0.1 | 0.7 | GO:0046600 | negative regulation of centriole replication(GO:0046600) |
0.1 | 1.4 | GO:0046036 | CTP biosynthetic process(GO:0006241) CTP metabolic process(GO:0046036) |
0.1 | 1.1 | GO:0006271 | DNA strand elongation involved in DNA replication(GO:0006271) |
0.1 | 0.4 | GO:0003221 | right ventricular cardiac muscle tissue morphogenesis(GO:0003221) |
0.1 | 4.8 | GO:0006284 | base-excision repair(GO:0006284) |
0.1 | 1.0 | GO:0033631 | cell-cell adhesion mediated by integrin(GO:0033631) |
0.1 | 0.5 | GO:1903378 | positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378) |
0.1 | 0.5 | GO:0017196 | N-terminal peptidyl-methionine acetylation(GO:0017196) |
0.1 | 0.4 | GO:0034773 | histone H4-K20 trimethylation(GO:0034773) |
0.1 | 0.8 | GO:0002903 | negative regulation of B cell apoptotic process(GO:0002903) |
0.1 | 1.2 | GO:2000810 | regulation of bicellular tight junction assembly(GO:2000810) |
0.1 | 0.9 | GO:0009437 | carnitine metabolic process(GO:0009437) |
0.0 | 1.4 | GO:0000413 | protein peptidyl-prolyl isomerization(GO:0000413) |
0.0 | 2.1 | GO:0090162 | establishment of epithelial cell polarity(GO:0090162) |
0.0 | 0.1 | GO:0021893 | cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871) |
0.0 | 0.1 | GO:0090071 | negative regulation of ribosome biogenesis(GO:0090071) |
0.0 | 0.2 | GO:1902416 | positive regulation of mRNA binding(GO:1902416) |
0.0 | 0.1 | GO:0075525 | viral translational termination-reinitiation(GO:0075525) |
0.0 | 1.3 | GO:2000272 | negative regulation of receptor activity(GO:2000272) |
0.0 | 0.2 | GO:0006083 | acetate metabolic process(GO:0006083) short-chain fatty acid biosynthetic process(GO:0051790) |
0.0 | 0.6 | GO:0015693 | magnesium ion transport(GO:0015693) |
0.0 | 0.9 | GO:0000470 | maturation of LSU-rRNA(GO:0000470) |
0.0 | 1.9 | GO:0002181 | cytoplasmic translation(GO:0002181) |
0.0 | 1.1 | GO:0050435 | beta-amyloid metabolic process(GO:0050435) |
0.0 | 0.9 | GO:0070897 | DNA-templated transcriptional preinitiation complex assembly(GO:0070897) |
0.0 | 0.4 | GO:0006335 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) |
0.0 | 0.1 | GO:0035441 | cell migration involved in vasculogenesis(GO:0035441) |
0.0 | 0.1 | GO:0061090 | positive regulation of sequestering of zinc ion(GO:0061090) |
0.0 | 0.7 | GO:0071391 | cellular response to estrogen stimulus(GO:0071391) |
0.0 | 0.6 | GO:0007080 | mitotic metaphase plate congression(GO:0007080) protein K11-linked ubiquitination(GO:0070979) |
0.0 | 0.2 | GO:0070072 | vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072) |
0.0 | 0.8 | GO:0043330 | response to exogenous dsRNA(GO:0043330) |
0.0 | 0.1 | GO:1903691 | positive regulation of wound healing, spreading of epidermal cells(GO:1903691) |
0.0 | 0.4 | GO:0019373 | epoxygenase P450 pathway(GO:0019373) |
0.0 | 0.8 | GO:1902653 | cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653) |
0.0 | 2.3 | GO:0015718 | monocarboxylic acid transport(GO:0015718) |
0.0 | 0.1 | GO:0006933 | negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 4.8 | GO:0035985 | senescence-associated heterochromatin focus(GO:0035985) |
0.5 | 1.5 | GO:0017109 | glutamate-cysteine ligase complex(GO:0017109) |
0.4 | 1.1 | GO:0043625 | delta DNA polymerase complex(GO:0043625) |
0.3 | 11.3 | GO:0000788 | nuclear nucleosome(GO:0000788) |
0.1 | 1.9 | GO:0042788 | polysomal ribosome(GO:0042788) |
0.1 | 0.8 | GO:0005672 | transcription factor TFIIA complex(GO:0005672) |
0.1 | 4.0 | GO:0045095 | keratin filament(GO:0045095) |
0.1 | 1.0 | GO:0044294 | dendritic growth cone(GO:0044294) |
0.0 | 0.5 | GO:0097136 | Bcl-2 family protein complex(GO:0097136) |
0.0 | 0.5 | GO:0031414 | N-terminal protein acetyltransferase complex(GO:0031414) |
0.0 | 1.6 | GO:0000786 | nucleosome(GO:0000786) |
0.0 | 0.7 | GO:0097431 | mitotic spindle pole(GO:0097431) |
0.0 | 0.7 | GO:0035327 | transcriptionally active chromatin(GO:0035327) |
0.0 | 1.3 | GO:0016592 | mediator complex(GO:0016592) |
0.0 | 0.6 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
0.0 | 0.9 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
0.0 | 1.7 | GO:0005811 | lipid particle(GO:0005811) |
0.0 | 0.1 | GO:0070652 | HAUS complex(GO:0070652) |
0.0 | 0.1 | GO:1990130 | Iml1 complex(GO:1990130) |
0.0 | 0.9 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
0.0 | 2.1 | GO:0005923 | bicellular tight junction(GO:0005923) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.6 | 2.8 | GO:1990254 | keratin filament binding(GO:1990254) |
0.5 | 1.5 | GO:0004357 | glutamate-cysteine ligase activity(GO:0004357) |
0.5 | 4.8 | GO:0051575 | 5'-deoxyribose-5-phosphate lyase activity(GO:0051575) |
0.4 | 1.3 | GO:0098809 | nitrite reductase activity(GO:0098809) |
0.4 | 3.0 | GO:0016936 | galactoside binding(GO:0016936) |
0.4 | 1.3 | GO:0009041 | uridylate kinase activity(GO:0009041) |
0.4 | 1.4 | GO:0003883 | CTP synthase activity(GO:0003883) |
0.3 | 1.5 | GO:0030280 | structural constituent of epidermis(GO:0030280) |
0.2 | 1.2 | GO:0038181 | bile acid receptor activity(GO:0038181) |
0.2 | 3.0 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
0.2 | 0.9 | GO:0016416 | carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416) |
0.1 | 1.0 | GO:0033691 | sialic acid binding(GO:0033691) |
0.1 | 0.5 | GO:0061575 | cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575) |
0.1 | 0.8 | GO:0097322 | 7SK snRNA binding(GO:0097322) |
0.1 | 1.1 | GO:0008242 | omega peptidase activity(GO:0008242) |
0.1 | 1.3 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
0.1 | 0.2 | GO:0003987 | acetate-CoA ligase activity(GO:0003987) |
0.1 | 13.4 | GO:0042393 | histone binding(GO:0042393) |
0.1 | 3.4 | GO:0008028 | monocarboxylic acid transmembrane transporter activity(GO:0008028) |
0.1 | 1.7 | GO:0016866 | intramolecular transferase activity(GO:0016866) |
0.0 | 3.1 | GO:0004601 | peroxidase activity(GO:0004601) |
0.0 | 0.5 | GO:0051434 | BH3 domain binding(GO:0051434) |
0.0 | 1.4 | GO:0051537 | 2 iron, 2 sulfur cluster binding(GO:0051537) |
0.0 | 1.1 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
0.0 | 0.5 | GO:0004596 | peptide alpha-N-acetyltransferase activity(GO:0004596) |
0.0 | 1.3 | GO:0046966 | thyroid hormone receptor binding(GO:0046966) |
0.0 | 1.4 | GO:0003755 | peptidyl-prolyl cis-trans isomerase activity(GO:0003755) |
0.0 | 0.6 | GO:0015095 | magnesium ion transmembrane transporter activity(GO:0015095) |
0.0 | 0.1 | GO:0001032 | RNA polymerase III type 3 promoter DNA binding(GO:0001032) |
0.0 | 0.8 | GO:0017025 | TBP-class protein binding(GO:0017025) |
0.0 | 0.1 | GO:0004311 | farnesyltranstransferase activity(GO:0004311) |
0.0 | 0.2 | GO:1990715 | mRNA CDS binding(GO:1990715) |
0.0 | 0.2 | GO:0070181 | small ribosomal subunit rRNA binding(GO:0070181) |
0.0 | 0.8 | GO:0071889 | 14-3-3 protein binding(GO:0071889) |
0.0 | 0.4 | GO:0070628 | proteasome binding(GO:0070628) |
0.0 | 2.5 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
0.0 | 0.1 | GO:0043532 | angiostatin binding(GO:0043532) |
0.0 | 0.4 | GO:0070330 | aromatase activity(GO:0070330) |
0.0 | 0.1 | GO:0046975 | histone methyltransferase activity (H3-K36 specific)(GO:0046975) |
0.0 | 0.4 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
0.0 | 1.9 | GO:0030674 | protein binding, bridging(GO:0030674) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 3.0 | PID P38 ALPHA BETA PATHWAY | Regulation of p38-alpha and p38-beta |
0.1 | 5.6 | PID IL4 2PATHWAY | IL4-mediated signaling events |
0.0 | 2.8 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
0.0 | 4.2 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
0.0 | 1.0 | PID INTEGRIN3 PATHWAY | Beta3 integrin cell surface interactions |
0.0 | 0.7 | PID AR NONGENOMIC PATHWAY | Nongenotropic Androgen signaling |
0.0 | 1.8 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
0.0 | 0.9 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
0.0 | 0.5 | PID IL6 7 PATHWAY | IL6-mediated signaling events |
0.0 | 1.5 | PID BETA CATENIN NUC PATHWAY | Regulation of nuclear beta catenin signaling and target gene transcription |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.6 | 4.8 | REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION | Genes involved in APOBEC3G mediated resistance to HIV-1 infection |
0.3 | 11.3 | REACTOME PACKAGING OF TELOMERE ENDS | Genes involved in Packaging Of Telomere Ends |
0.1 | 1.1 | REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND | Genes involved in Removal of the Flap Intermediate from the C-strand |
0.1 | 1.8 | REACTOME CHOLESTEROL BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
0.1 | 1.9 | REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |
0.1 | 1.4 | REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
0.1 | 1.5 | REACTOME SULFUR AMINO ACID METABOLISM | Genes involved in Sulfur amino acid metabolism |
0.0 | 0.8 | REACTOME SOS MEDIATED SIGNALLING | Genes involved in SOS-mediated signalling |
0.0 | 0.2 | REACTOME ETHANOL OXIDATION | Genes involved in Ethanol oxidation |
0.0 | 1.0 | REACTOME BASIGIN INTERACTIONS | Genes involved in Basigin interactions |
0.0 | 0.6 | REACTOME PHOSPHORYLATION OF THE APC C | Genes involved in Phosphorylation of the APC/C |
0.0 | 2.8 | REACTOME PEPTIDE CHAIN ELONGATION | Genes involved in Peptide chain elongation |
0.0 | 0.4 | REACTOME FGFR1 LIGAND BINDING AND ACTIVATION | Genes involved in FGFR1 ligand binding and activation |
0.0 | 0.8 | REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING | Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening |
0.0 | 0.4 | REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE | Genes involved in Cytochrome P450 - arranged by substrate type |