avrg: GSE58827: Dynamics of the Mouse Liver
Gene Symbol | Gene ID | Gene Info |
---|---|---|
Ddit3
|
ENSMUSG00000025408.9 | DNA-damage inducible transcript 3 |
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Ddit3 | mm10_v2_chr10_+_127290774_127290803 | -0.75 | 1.2e-07 | Click! |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.9 | 2.7 | GO:0090341 | negative regulation of secretion of lysosomal enzymes(GO:0090341) |
0.8 | 4.9 | GO:1902998 | regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998) |
0.5 | 1.4 | GO:0015882 | L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904) |
0.5 | 1.4 | GO:0061144 | alveolar secondary septum development(GO:0061144) |
0.4 | 1.1 | GO:0019859 | pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859) |
0.3 | 1.2 | GO:0035606 | peptidyl-cysteine S-trans-nitrosylation(GO:0035606) |
0.3 | 0.8 | GO:0034334 | adherens junction maintenance(GO:0034334) |
0.2 | 2.9 | GO:0006751 | glutathione catabolic process(GO:0006751) |
0.2 | 1.3 | GO:2000124 | regulation of endocannabinoid signaling pathway(GO:2000124) |
0.2 | 0.5 | GO:0010845 | positive regulation of reciprocal meiotic recombination(GO:0010845) |
0.2 | 0.9 | GO:0033540 | fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540) |
0.2 | 0.9 | GO:1903071 | positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071) |
0.1 | 1.0 | GO:0030242 | pexophagy(GO:0030242) |
0.1 | 0.4 | GO:0071550 | death-inducing signaling complex assembly(GO:0071550) |
0.1 | 1.2 | GO:0032464 | positive regulation of protein homooligomerization(GO:0032464) |
0.1 | 1.0 | GO:0090166 | Golgi disassembly(GO:0090166) regulation of chaperone-mediated autophagy(GO:1904714) |
0.1 | 0.4 | GO:0016240 | autophagosome docking(GO:0016240) |
0.1 | 0.6 | GO:0009407 | toxin catabolic process(GO:0009407) secondary metabolite catabolic process(GO:0090487) |
0.1 | 0.4 | GO:1901475 | pyruvate transmembrane transport(GO:1901475) |
0.1 | 0.4 | GO:0071799 | response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799) |
0.1 | 0.4 | GO:0010841 | positive regulation of circadian sleep/wake cycle, wakefulness(GO:0010841) |
0.1 | 0.3 | GO:0070086 | ubiquitin-dependent endocytosis(GO:0070086) |
0.1 | 0.4 | GO:0006189 | 'de novo' IMP biosynthetic process(GO:0006189) |
0.1 | 1.7 | GO:0014049 | positive regulation of glutamate secretion(GO:0014049) |
0.1 | 0.3 | GO:2001055 | positive regulation of mesenchymal cell apoptotic process(GO:2001055) |
0.1 | 0.3 | GO:0031635 | adenylate cyclase-inhibiting opioid receptor signaling pathway(GO:0031635) |
0.1 | 0.1 | GO:0010578 | regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579) |
0.1 | 0.5 | GO:0015671 | oxygen transport(GO:0015671) |
0.1 | 0.3 | GO:0060066 | oviduct development(GO:0060066) |
0.1 | 0.2 | GO:0032468 | cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) manganese ion homeostasis(GO:0055071) |
0.1 | 0.6 | GO:0060763 | mammary duct terminal end bud growth(GO:0060763) |
0.1 | 0.4 | GO:0060054 | positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054) |
0.1 | 1.8 | GO:0015986 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
0.1 | 0.8 | GO:0070493 | thrombin receptor signaling pathway(GO:0070493) |
0.1 | 0.6 | GO:0061635 | regulation of protein complex stability(GO:0061635) |
0.0 | 2.7 | GO:0003298 | physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049) |
0.0 | 0.3 | GO:0045218 | zonula adherens maintenance(GO:0045218) |
0.0 | 0.2 | GO:0018364 | peptidyl-glutamine methylation(GO:0018364) |
0.0 | 0.6 | GO:0090336 | positive regulation of brown fat cell differentiation(GO:0090336) |
0.0 | 0.3 | GO:2000483 | negative regulation of interleukin-8 secretion(GO:2000483) |
0.0 | 1.0 | GO:0045475 | locomotor rhythm(GO:0045475) |
0.0 | 0.3 | GO:2000258 | negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258) |
0.0 | 0.2 | GO:0043152 | induction of bacterial agglutination(GO:0043152) |
0.0 | 1.3 | GO:0031424 | keratinization(GO:0031424) |
0.0 | 0.3 | GO:0032308 | positive regulation of prostaglandin secretion(GO:0032308) |
0.0 | 0.1 | GO:0060061 | Spemann organizer formation(GO:0060061) |
0.0 | 0.9 | GO:0032012 | ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012) |
0.0 | 0.1 | GO:0035481 | Notch signaling pathway involved in heart induction(GO:0003137) regulation of Notch signaling pathway involved in heart induction(GO:0035480) positive regulation of Notch signaling pathway involved in heart induction(GO:0035481) regulation of heart induction by regulation of canonical Wnt signaling pathway(GO:0090081) |
0.0 | 0.5 | GO:0015874 | norepinephrine transport(GO:0015874) |
0.0 | 1.0 | GO:0006084 | acetyl-CoA metabolic process(GO:0006084) |
0.0 | 0.4 | GO:0071732 | cellular response to nitric oxide(GO:0071732) |
0.0 | 0.6 | GO:0099517 | anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517) |
0.0 | 0.6 | GO:0042572 | retinol metabolic process(GO:0042572) |
0.0 | 1.7 | GO:0006749 | glutathione metabolic process(GO:0006749) |
0.0 | 0.6 | GO:0007252 | I-kappaB phosphorylation(GO:0007252) |
0.0 | 0.4 | GO:0016540 | protein autoprocessing(GO:0016540) |
0.0 | 0.7 | GO:0045956 | positive regulation of calcium ion-dependent exocytosis(GO:0045956) |
0.0 | 0.1 | GO:0099527 | postsynapse to nucleus signaling pathway(GO:0099527) |
0.0 | 0.1 | GO:0042275 | error-free postreplication DNA repair(GO:0042275) |
0.0 | 0.3 | GO:0090286 | cytoskeletal anchoring at nuclear membrane(GO:0090286) |
0.0 | 0.1 | GO:0060406 | positive regulation of penile erection(GO:0060406) |
0.0 | 0.2 | GO:0048207 | vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) |
0.0 | 0.6 | GO:0010107 | potassium ion import(GO:0010107) |
0.0 | 0.3 | GO:0035881 | amacrine cell differentiation(GO:0035881) |
0.0 | 0.1 | GO:0071431 | tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431) |
0.0 | 0.1 | GO:0033184 | positive regulation of histone ubiquitination(GO:0033184) |
0.0 | 0.3 | GO:0033194 | response to hydroperoxide(GO:0033194) |
0.0 | 0.3 | GO:1900037 | regulation of cellular response to hypoxia(GO:1900037) |
0.0 | 0.2 | GO:0042407 | cristae formation(GO:0042407) |
0.0 | 0.1 | GO:0060124 | positive regulation of growth hormone secretion(GO:0060124) |
0.0 | 2.1 | GO:0015718 | monocarboxylic acid transport(GO:0015718) |
0.0 | 0.4 | GO:0045663 | positive regulation of myoblast differentiation(GO:0045663) |
0.0 | 0.4 | GO:0006904 | vesicle docking involved in exocytosis(GO:0006904) |
0.0 | 0.1 | GO:0051835 | positive regulation of synapse structural plasticity(GO:0051835) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 4.9 | GO:0097418 | neurofibrillary tangle(GO:0097418) |
0.3 | 1.0 | GO:0097057 | TRAF2-GSTP1 complex(GO:0097057) |
0.2 | 0.9 | GO:1990037 | Lewy body core(GO:1990037) |
0.2 | 1.2 | GO:0097452 | GAIT complex(GO:0097452) |
0.1 | 0.4 | GO:0097629 | extrinsic component of omegasome membrane(GO:0097629) |
0.1 | 1.8 | GO:0000276 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) |
0.1 | 1.3 | GO:0043196 | varicosity(GO:0043196) |
0.0 | 0.4 | GO:1990712 | HFE-transferrin receptor complex(GO:1990712) |
0.0 | 1.3 | GO:0001533 | cornified envelope(GO:0001533) |
0.0 | 0.6 | GO:1904115 | axon cytoplasm(GO:1904115) |
0.0 | 0.6 | GO:0030008 | TRAPP complex(GO:0030008) |
0.0 | 0.2 | GO:0031428 | box C/D snoRNP complex(GO:0031428) |
0.0 | 1.3 | GO:0032809 | neuronal cell body membrane(GO:0032809) |
0.0 | 0.3 | GO:0005915 | zonula adherens(GO:0005915) |
0.0 | 0.1 | GO:0030914 | STAGA complex(GO:0030914) |
0.0 | 0.2 | GO:0061617 | MICOS complex(GO:0061617) |
0.0 | 0.5 | GO:0016514 | SWI/SNF complex(GO:0016514) |
0.0 | 0.3 | GO:0016600 | flotillin complex(GO:0016600) |
0.0 | 0.4 | GO:0031143 | pseudopodium(GO:0031143) |
0.0 | 0.6 | GO:0034364 | high-density lipoprotein particle(GO:0034364) |
0.0 | 0.1 | GO:0031372 | UBC13-MMS2 complex(GO:0031372) |
0.0 | 0.2 | GO:0005577 | fibrinogen complex(GO:0005577) |
0.0 | 1.4 | GO:0009925 | basal plasma membrane(GO:0009925) |
0.0 | 0.4 | GO:0031305 | integral component of mitochondrial inner membrane(GO:0031305) |
0.0 | 0.7 | GO:0030964 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
0.0 | 3.9 | GO:0005802 | trans-Golgi network(GO:0005802) |
0.0 | 0.9 | GO:0097610 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
0.0 | 0.4 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
0.0 | 0.8 | GO:0031941 | filamentous actin(GO:0031941) |
0.0 | 1.0 | GO:0098791 | Golgi subcompartment(GO:0098791) |
0.0 | 0.9 | GO:0005778 | peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903) |
0.0 | 2.1 | GO:0090575 | RNA polymerase II transcription factor complex(GO:0090575) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.6 | 2.9 | GO:0003839 | gamma-glutamylcyclotransferase activity(GO:0003839) |
0.5 | 2.7 | GO:0032810 | sterol response element binding(GO:0032810) |
0.5 | 1.4 | GO:0070890 | L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890) |
0.4 | 1.2 | GO:0035605 | peptidyl-cysteine S-nitrosylase activity(GO:0035605) |
0.3 | 1.3 | GO:0030280 | structural constituent of epidermis(GO:0030280) |
0.2 | 4.9 | GO:0051787 | misfolded protein binding(GO:0051787) |
0.2 | 0.6 | GO:0030614 | oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610) |
0.2 | 1.0 | GO:0003986 | acetyl-CoA hydrolase activity(GO:0003986) |
0.2 | 0.5 | GO:0005333 | norepinephrine transmembrane transporter activity(GO:0005333) |
0.2 | 1.1 | GO:0016812 | nucleobase binding(GO:0002054) hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812) |
0.2 | 0.9 | GO:0016401 | palmitoyl-CoA oxidase activity(GO:0016401) |
0.2 | 1.4 | GO:0005007 | fibroblast growth factor-activated receptor activity(GO:0005007) |
0.1 | 1.8 | GO:0046933 | proton-transporting ATP synthase activity, rotational mechanism(GO:0046933) |
0.1 | 0.5 | GO:0005250 | A-type (transient outward) potassium channel activity(GO:0005250) |
0.1 | 0.4 | GO:0050833 | pyruvate transmembrane transporter activity(GO:0050833) |
0.1 | 1.3 | GO:0047372 | acylglycerol lipase activity(GO:0047372) |
0.1 | 1.6 | GO:0016805 | dipeptidase activity(GO:0016805) |
0.1 | 0.4 | GO:0051373 | FATZ binding(GO:0051373) |
0.1 | 0.6 | GO:0035662 | Toll-like receptor 4 binding(GO:0035662) |
0.1 | 0.4 | GO:0004719 | protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719) |
0.1 | 0.2 | GO:0004947 | bradykinin receptor activity(GO:0004947) |
0.1 | 0.3 | GO:0038049 | glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051) |
0.1 | 0.5 | GO:0005344 | oxygen transporter activity(GO:0005344) |
0.1 | 0.7 | GO:0004791 | thioredoxin-disulfide reductase activity(GO:0004791) |
0.1 | 0.2 | GO:0015410 | manganese-transporting ATPase activity(GO:0015410) |
0.1 | 5.7 | GO:0008170 | N-methyltransferase activity(GO:0008170) |
0.1 | 1.3 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
0.0 | 0.7 | GO:0031386 | protein tag(GO:0031386) |
0.0 | 0.3 | GO:0004985 | opioid receptor activity(GO:0004985) |
0.0 | 0.4 | GO:0036122 | BMP binding(GO:0036122) |
0.0 | 0.4 | GO:0086080 | protein binding involved in heterotypic cell-cell adhesion(GO:0086080) |
0.0 | 2.2 | GO:0008028 | monocarboxylic acid transmembrane transporter activity(GO:0008028) |
0.0 | 0.6 | GO:0008106 | alcohol dehydrogenase (NADP+) activity(GO:0008106) |
0.0 | 1.0 | GO:0043295 | glutathione peroxidase activity(GO:0004602) glutathione binding(GO:0043295) oligopeptide binding(GO:1900750) |
0.0 | 0.2 | GO:0009019 | tRNA (guanine-N1-)-methyltransferase activity(GO:0009019) |
0.0 | 0.1 | GO:0004962 | endothelin receptor activity(GO:0004962) |
0.0 | 0.4 | GO:0004955 | prostaglandin receptor activity(GO:0004955) |
0.0 | 1.0 | GO:0000062 | fatty-acyl-CoA binding(GO:0000062) |
0.0 | 0.5 | GO:0015929 | hexosaminidase activity(GO:0015929) |
0.0 | 0.9 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
0.0 | 0.7 | GO:0008137 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
0.0 | 0.1 | GO:0045322 | unmethylated CpG binding(GO:0045322) |
0.0 | 0.3 | GO:0070097 | delta-catenin binding(GO:0070097) |
0.0 | 0.6 | GO:0005242 | inward rectifier potassium channel activity(GO:0005242) |
0.0 | 0.3 | GO:0045294 | alpha-catenin binding(GO:0045294) |
0.0 | 0.8 | GO:0003785 | actin monomer binding(GO:0003785) |
0.0 | 0.4 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
0.0 | 0.3 | GO:0004708 | MAP kinase kinase activity(GO:0004708) |
0.0 | 0.3 | GO:0043495 | protein anchor(GO:0043495) |
0.0 | 1.0 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
0.0 | 0.4 | GO:0031434 | mitogen-activated protein kinase kinase binding(GO:0031434) |
0.0 | 0.3 | GO:0005003 | ephrin receptor activity(GO:0005003) |
0.0 | 0.8 | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547) |
0.0 | 2.0 | GO:0052689 | carboxylic ester hydrolase activity(GO:0052689) |
0.0 | 0.3 | GO:0016881 | acid-amino acid ligase activity(GO:0016881) |
0.0 | 1.0 | GO:0002039 | p53 binding(GO:0002039) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 3.9 | PID MYC REPRESS PATHWAY | Validated targets of C-MYC transcriptional repression |
0.1 | 2.7 | PID RXR VDR PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
0.0 | 4.9 | PID E2F PATHWAY | E2F transcription factor network |
0.0 | 1.7 | PID FAK PATHWAY | Signaling events mediated by focal adhesion kinase |
0.0 | 0.3 | PID ANTHRAX PATHWAY | Cellular roles of Anthrax toxin |
0.0 | 1.6 | PID FGF PATHWAY | FGF signaling pathway |
0.0 | 0.6 | PID A6B1 A6B4 INTEGRIN PATHWAY | a6b1 and a6b4 Integrin signaling |
0.0 | 0.7 | ST G ALPHA I PATHWAY | G alpha i Pathway |
0.0 | 1.3 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
0.0 | 0.8 | PID HEDGEHOG GLI PATHWAY | Hedgehog signaling events mediated by Gli proteins |
0.0 | 0.3 | PID EPHA FWDPATHWAY | EPHA forward signaling |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 1.8 | REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING | Genes involved in Formation of ATP by chemiosmotic coupling |
0.1 | 1.4 | REACTOME SIGNALING BY FGFR3 MUTANTS | Genes involved in Signaling by FGFR3 mutants |
0.1 | 1.6 | REACTOME CRMPS IN SEMA3A SIGNALING | Genes involved in CRMPs in Sema3A signaling |
0.1 | 1.1 | REACTOME PYRIMIDINE CATABOLISM | Genes involved in Pyrimidine catabolism |
0.1 | 5.4 | REACTOME PHASE II CONJUGATION | Genes involved in Phase II conjugation |
0.0 | 1.1 | REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS | Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
0.0 | 5.1 | REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | Genes involved in Response to elevated platelet cytosolic Ca2+ |
0.0 | 0.9 | REACTOME ALPHA LINOLENIC ACID ALA METABOLISM | Genes involved in alpha-linolenic acid (ALA) metabolism |
0.0 | 0.9 | REACTOME ACTIVATION OF GENES BY ATF4 | Genes involved in Activation of Genes by ATF4 |
0.0 | 0.7 | REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC | Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC |
0.0 | 0.4 | REACTOME PROSTANOID LIGAND RECEPTORS | Genes involved in Prostanoid ligand receptors |
0.0 | 3.0 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
0.0 | 1.2 | REACTOME GLUCONEOGENESIS | Genes involved in Gluconeogenesis |
0.0 | 0.4 | REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
0.0 | 0.4 | REACTOME RAF MAP KINASE CASCADE | Genes involved in RAF/MAP kinase cascade |
0.0 | 0.5 | REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS | Genes involved in Na+/Cl- dependent neurotransmitter transporters |
0.0 | 1.4 | REACTOME METABOLISM OF VITAMINS AND COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
0.0 | 0.9 | REACTOME VOLTAGE GATED POTASSIUM CHANNELS | Genes involved in Voltage gated Potassium channels |
0.0 | 0.7 | REACTOME G ALPHA Z SIGNALLING EVENTS | Genes involved in G alpha (z) signalling events |
0.0 | 0.3 | REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION | Genes involved in activated TAK1 mediates p38 MAPK activation |
0.0 | 0.3 | REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS | Genes involved in Apoptotic cleavage of cell adhesion proteins |
0.0 | 0.6 | REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
0.0 | 0.6 | REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS | Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits |