avrg: GSE58827: Dynamics of the Mouse Liver
Gene Symbol | Gene ID | Gene Info |
---|---|---|
Tead1
|
ENSMUSG00000055320.10 | TEA domain family member 1 |
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Tead1 | mm10_v2_chr7_+_112679327_112679373 | 0.12 | 4.9e-01 | Click! |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.6 | 1.9 | GO:0032849 | positive regulation of cellular pH reduction(GO:0032849) |
0.6 | 1.7 | GO:0070104 | negative regulation of interleukin-6-mediated signaling pathway(GO:0070104) |
0.6 | 2.8 | GO:0006189 | 'de novo' IMP biosynthetic process(GO:0006189) |
0.5 | 3.7 | GO:2000124 | regulation of endocannabinoid signaling pathway(GO:2000124) |
0.4 | 2.0 | GO:0070318 | positive regulation of G0 to G1 transition(GO:0070318) |
0.4 | 1.5 | GO:0051562 | negative regulation of mitochondrial calcium ion concentration(GO:0051562) |
0.3 | 0.9 | GO:1904395 | positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) |
0.3 | 1.6 | GO:0090038 | negative regulation of protein kinase C signaling(GO:0090038) |
0.3 | 1.4 | GO:0042360 | vitamin E metabolic process(GO:0042360) |
0.3 | 0.8 | GO:0046710 | GDP metabolic process(GO:0046710) |
0.3 | 1.3 | GO:0035426 | extracellular matrix-cell signaling(GO:0035426) |
0.3 | 1.5 | GO:0098734 | protein depalmitoylation(GO:0002084) negative regulation of Golgi to plasma membrane protein transport(GO:0042997) negative regulation of establishment of protein localization to plasma membrane(GO:0090005) macromolecule depalmitoylation(GO:0098734) |
0.3 | 0.8 | GO:0061348 | canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) planar cell polarity pathway involved in outflow tract morphogenesis(GO:0061347) planar cell polarity pathway involved in ventricular septum morphogenesis(GO:0061348) planar cell polarity pathway involved in cardiac right atrium morphogenesis(GO:0061349) planar cell polarity pathway involved in cardiac muscle tissue morphogenesis(GO:0061350) planar cell polarity pathway involved in pericardium morphogenesis(GO:0061354) receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118) |
0.2 | 1.2 | GO:0072719 | cellular response to cisplatin(GO:0072719) |
0.2 | 0.8 | GO:0006481 | C-terminal protein methylation(GO:0006481) |
0.2 | 0.6 | GO:0021530 | spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) |
0.2 | 2.6 | GO:0055059 | asymmetric neuroblast division(GO:0055059) |
0.2 | 2.4 | GO:0010839 | negative regulation of keratinocyte proliferation(GO:0010839) |
0.2 | 1.1 | GO:0002528 | regulation of vascular permeability involved in acute inflammatory response(GO:0002528) |
0.2 | 2.3 | GO:0035845 | photoreceptor cell outer segment organization(GO:0035845) |
0.2 | 0.9 | GO:1902732 | positive regulation of chondrocyte proliferation(GO:1902732) |
0.2 | 1.1 | GO:1990573 | potassium ion import across plasma membrane(GO:1990573) |
0.1 | 0.3 | GO:0050883 | musculoskeletal movement, spinal reflex action(GO:0050883) |
0.1 | 1.6 | GO:0072307 | metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307) |
0.1 | 8.1 | GO:0003301 | physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049) |
0.1 | 0.6 | GO:1900085 | negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609) |
0.1 | 0.6 | GO:0060298 | positive regulation of sarcomere organization(GO:0060298) |
0.1 | 5.0 | GO:0006890 | retrograde vesicle-mediated transport, Golgi to ER(GO:0006890) |
0.1 | 0.6 | GO:0038018 | Wnt receptor catabolic process(GO:0038018) |
0.1 | 1.4 | GO:0060052 | neurofilament cytoskeleton organization(GO:0060052) |
0.1 | 4.3 | GO:0050891 | multicellular organismal water homeostasis(GO:0050891) |
0.1 | 0.6 | GO:0019348 | dolichol metabolic process(GO:0019348) GDP-mannose metabolic process(GO:0019673) |
0.1 | 0.9 | GO:0010572 | positive regulation of platelet activation(GO:0010572) |
0.1 | 2.5 | GO:0042219 | cellular modified amino acid catabolic process(GO:0042219) |
0.1 | 0.7 | GO:0061366 | behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368) |
0.1 | 0.4 | GO:0003406 | retinal pigment epithelium development(GO:0003406) |
0.1 | 3.1 | GO:0046621 | negative regulation of organ growth(GO:0046621) |
0.1 | 0.6 | GO:0044791 | modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791) |
0.1 | 0.2 | GO:0044339 | canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339) |
0.1 | 5.1 | GO:0030032 | lamellipodium assembly(GO:0030032) |
0.1 | 0.3 | GO:0003219 | cardiac right ventricle formation(GO:0003219) |
0.1 | 0.6 | GO:0090557 | establishment of endothelial intestinal barrier(GO:0090557) |
0.0 | 0.5 | GO:0031274 | positive regulation of pseudopodium assembly(GO:0031274) |
0.0 | 4.4 | GO:0032760 | positive regulation of tumor necrosis factor production(GO:0032760) |
0.0 | 0.7 | GO:1900454 | positive regulation of long term synaptic depression(GO:1900454) |
0.0 | 1.4 | GO:0045104 | intermediate filament cytoskeleton organization(GO:0045104) |
0.0 | 1.1 | GO:0000132 | establishment of mitotic spindle orientation(GO:0000132) |
0.0 | 0.3 | GO:1904259 | regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197) |
0.0 | 0.9 | GO:0006607 | NLS-bearing protein import into nucleus(GO:0006607) |
0.0 | 2.3 | GO:0006940 | regulation of smooth muscle contraction(GO:0006940) |
0.0 | 1.6 | GO:0015914 | phospholipid transport(GO:0015914) |
0.0 | 0.8 | GO:0018345 | protein palmitoylation(GO:0018345) |
0.0 | 1.3 | GO:0050873 | brown fat cell differentiation(GO:0050873) |
0.0 | 0.7 | GO:0010971 | positive regulation of G2/M transition of mitotic cell cycle(GO:0010971) |
0.0 | 0.8 | GO:0090200 | positive regulation of release of cytochrome c from mitochondria(GO:0090200) |
0.0 | 0.2 | GO:0021894 | cerebral cortex GABAergic interneuron development(GO:0021894) |
0.0 | 1.2 | GO:0007520 | myoblast fusion(GO:0007520) |
0.0 | 0.3 | GO:0071688 | striated muscle myosin thick filament assembly(GO:0071688) |
0.0 | 0.2 | GO:0048739 | cardiac muscle fiber development(GO:0048739) |
0.0 | 0.3 | GO:0001946 | lymphangiogenesis(GO:0001946) |
0.0 | 0.3 | GO:0002089 | lens morphogenesis in camera-type eye(GO:0002089) |
0.0 | 0.4 | GO:0070536 | protein K63-linked deubiquitination(GO:0070536) |
0.0 | 0.4 | GO:0048240 | sperm capacitation(GO:0048240) |
0.0 | 0.4 | GO:0007205 | protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205) |
0.0 | 0.3 | GO:0010842 | retina layer formation(GO:0010842) |
0.0 | 0.3 | GO:0007026 | negative regulation of microtubule depolymerization(GO:0007026) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.6 | 1.7 | GO:0005900 | oncostatin-M receptor complex(GO:0005900) |
0.3 | 1.3 | GO:0005610 | laminin-5 complex(GO:0005610) |
0.3 | 2.3 | GO:0030478 | actin cap(GO:0030478) |
0.2 | 1.4 | GO:0000938 | GARP complex(GO:0000938) |
0.2 | 0.8 | GO:1990851 | Wnt-Frizzled-LRP5/6 complex(GO:1990851) |
0.2 | 4.3 | GO:0034706 | sodium channel complex(GO:0034706) |
0.2 | 0.5 | GO:0071149 | TEAD-2-YAP complex(GO:0071149) |
0.1 | 0.6 | GO:0033185 | dolichol-phosphate-mannose synthase complex(GO:0033185) |
0.1 | 0.4 | GO:0097598 | sperm cytoplasmic droplet(GO:0097598) |
0.1 | 0.6 | GO:0005863 | striated muscle myosin thick filament(GO:0005863) |
0.1 | 0.4 | GO:0000308 | cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308) |
0.1 | 0.8 | GO:0030991 | intraciliary transport particle A(GO:0030991) |
0.1 | 1.1 | GO:0016600 | flotillin complex(GO:0016600) |
0.1 | 1.1 | GO:0030877 | beta-catenin destruction complex(GO:0030877) |
0.1 | 2.0 | GO:0043196 | varicosity(GO:0043196) |
0.1 | 0.7 | GO:0097197 | tetraspanin-enriched microdomain(GO:0097197) |
0.1 | 4.4 | GO:0005871 | kinesin complex(GO:0005871) |
0.0 | 4.7 | GO:0001750 | photoreceptor outer segment(GO:0001750) |
0.0 | 1.4 | GO:0045095 | keratin filament(GO:0045095) |
0.0 | 0.6 | GO:0046581 | intercellular canaliculus(GO:0046581) |
0.0 | 0.6 | GO:0034098 | VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) |
0.0 | 0.6 | GO:0030126 | COPI vesicle coat(GO:0030126) |
0.0 | 2.0 | GO:0005801 | cis-Golgi network(GO:0005801) |
0.0 | 10.8 | GO:0014069 | postsynaptic density(GO:0014069) |
0.0 | 0.3 | GO:0045180 | basal cortex(GO:0045180) |
0.0 | 0.3 | GO:0071564 | npBAF complex(GO:0071564) |
0.0 | 0.3 | GO:0033391 | chromatoid body(GO:0033391) |
0.0 | 0.9 | GO:0001772 | immunological synapse(GO:0001772) |
0.0 | 1.0 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.6 | 1.7 | GO:0004923 | interleukin-6 receptor activity(GO:0004915) leukemia inhibitory factor receptor activity(GO:0004923) interleukin-6 binding(GO:0019981) |
0.5 | 2.5 | GO:0003839 | gamma-glutamylcyclotransferase activity(GO:0003839) |
0.5 | 1.9 | GO:0031893 | vasopressin receptor binding(GO:0031893) |
0.4 | 4.3 | GO:0015280 | ligand-gated sodium channel activity(GO:0015280) |
0.4 | 1.5 | GO:0035276 | ethanol binding(GO:0035276) |
0.3 | 1.4 | GO:1990254 | keratin filament binding(GO:1990254) |
0.3 | 0.8 | GO:0044715 | 8-oxo-dGDP phosphatase activity(GO:0044715) |
0.3 | 0.8 | GO:0071936 | coreceptor activity involved in Wnt signaling pathway(GO:0071936) |
0.2 | 3.7 | GO:0047372 | acylglycerol lipase activity(GO:0047372) |
0.2 | 1.6 | GO:0004556 | alpha-amylase activity(GO:0004556) |
0.2 | 0.8 | GO:0003880 | protein C-terminal carboxyl O-methyltransferase activity(GO:0003880) |
0.2 | 1.1 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
0.2 | 1.5 | GO:0098599 | palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599) |
0.1 | 1.3 | GO:0043237 | laminin-1 binding(GO:0043237) |
0.1 | 0.6 | GO:0004582 | dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582) |
0.1 | 3.3 | GO:0045295 | gamma-catenin binding(GO:0045295) |
0.1 | 2.3 | GO:0043855 | cyclic nucleotide-gated ion channel activity(GO:0043855) |
0.1 | 0.6 | GO:0070320 | inward rectifier potassium channel inhibitor activity(GO:0070320) |
0.1 | 0.5 | GO:0032450 | maltose alpha-glucosidase activity(GO:0032450) |
0.1 | 1.1 | GO:0070016 | armadillo repeat domain binding(GO:0070016) |
0.1 | 1.2 | GO:0005375 | copper ion transmembrane transporter activity(GO:0005375) |
0.1 | 2.8 | GO:0016881 | acid-amino acid ligase activity(GO:0016881) |
0.1 | 0.6 | GO:0030368 | interleukin-17 receptor activity(GO:0030368) |
0.1 | 1.9 | GO:0005520 | insulin-like growth factor binding(GO:0005520) |
0.1 | 0.5 | GO:0015379 | potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820) |
0.1 | 0.6 | GO:0071253 | connexin binding(GO:0071253) |
0.1 | 0.6 | GO:0031433 | telethonin binding(GO:0031433) |
0.1 | 1.1 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
0.1 | 1.6 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
0.0 | 1.2 | GO:0008327 | methyl-CpG binding(GO:0008327) |
0.0 | 0.9 | GO:0008510 | sodium:bicarbonate symporter activity(GO:0008510) |
0.0 | 0.4 | GO:0045294 | alpha-catenin binding(GO:0045294) |
0.0 | 0.2 | GO:0030899 | calcium-dependent ATPase activity(GO:0030899) |
0.0 | 0.5 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
0.0 | 0.8 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
0.0 | 0.9 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
0.0 | 2.4 | GO:0032947 | protein complex scaffold(GO:0032947) |
0.0 | 0.8 | GO:0019707 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707) |
0.0 | 0.3 | GO:0097493 | structural molecule activity conferring elasticity(GO:0097493) |
0.0 | 0.4 | GO:0003708 | retinoic acid receptor activity(GO:0003708) |
0.0 | 0.5 | GO:0070064 | proline-rich region binding(GO:0070064) |
0.0 | 0.2 | GO:0016175 | superoxide-generating NADPH oxidase activity(GO:0016175) |
0.0 | 0.7 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
0.0 | 4.5 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
0.0 | 0.7 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
0.0 | 0.4 | GO:0035497 | cAMP response element binding(GO:0035497) |
0.0 | 1.3 | GO:0004722 | protein serine/threonine phosphatase activity(GO:0004722) |
0.0 | 1.7 | GO:0019905 | syntaxin binding(GO:0019905) |
0.0 | 0.5 | GO:0071837 | HMG box domain binding(GO:0071837) |
0.0 | 0.6 | GO:0005109 | frizzled binding(GO:0005109) |
0.0 | 0.2 | GO:0038191 | neuropilin binding(GO:0038191) |
0.0 | 0.4 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
0.0 | 0.3 | GO:0016922 | ligand-dependent nuclear receptor binding(GO:0016922) |
0.0 | 1.8 | GO:0001085 | RNA polymerase II transcription factor binding(GO:0001085) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 1.2 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
0.1 | 2.3 | PID RHODOPSIN PATHWAY | Visual signal transduction: Rods |
0.1 | 1.5 | PID LPA4 PATHWAY | LPA4-mediated signaling events |
0.1 | 2.5 | NABA BASEMENT MEMBRANES | Genes encoding structural components of basement membranes |
0.1 | 0.4 | ST INTERFERON GAMMA PATHWAY | Interferon gamma pathway. |
0.0 | 1.7 | PID IL27 PATHWAY | IL27-mediated signaling events |
0.0 | 0.7 | PID FAK PATHWAY | Signaling events mediated by focal adhesion kinase |
0.0 | 1.4 | PID WNT CANONICAL PATHWAY | Canonical Wnt signaling pathway |
0.0 | 2.4 | PID NFAT TFPATHWAY | Calcineurin-regulated NFAT-dependent transcription in lymphocytes |
0.0 | 1.1 | ST MYOCYTE AD PATHWAY | Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway. |
0.0 | 1.9 | PID RAC1 REG PATHWAY | Regulation of RAC1 activity |
0.0 | 1.6 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
0.0 | 0.8 | ST ERK1 ERK2 MAPK PATHWAY | ERK1/ERK2 MAPK Pathway |
0.0 | 1.0 | PID HDAC CLASSII PATHWAY | Signaling events mediated by HDAC Class II |
0.0 | 0.9 | PID VEGFR1 2 PATHWAY | Signaling events mediated by VEGFR1 and VEGFR2 |
0.0 | 0.4 | PID RETINOIC ACID PATHWAY | Retinoic acid receptors-mediated signaling |
0.0 | 0.7 | PID REG GR PATHWAY | Glucocorticoid receptor regulatory network |
0.0 | 0.6 | PID ECADHERIN NASCENT AJ PATHWAY | E-cadherin signaling in the nascent adherens junction |
0.0 | 1.1 | PID BETA CATENIN NUC PATHWAY | Regulation of nuclear beta catenin signaling and target gene transcription |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 2.8 | REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
0.2 | 4.3 | REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS | Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
0.1 | 1.7 | REACTOME IL 6 SIGNALING | Genes involved in Interleukin-6 signaling |
0.1 | 5.6 | REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION | Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression |
0.1 | 1.6 | REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK | Genes involved in Negative regulation of the PI3K/AKT network |
0.1 | 2.7 | REACTOME DCC MEDIATED ATTRACTIVE SIGNALING | Genes involved in DCC mediated attractive signaling |
0.1 | 1.4 | REACTOME HDL MEDIATED LIPID TRANSPORT | Genes involved in HDL-mediated lipid transport |
0.1 | 1.5 | REACTOME ENOS ACTIVATION AND REGULATION | Genes involved in eNOS activation and regulation |
0.1 | 1.0 | REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY | Genes involved in Post-chaperonin tubulin folding pathway |
0.1 | 0.6 | REACTOME COPI MEDIATED TRANSPORT | Genes involved in COPI Mediated Transport |
0.0 | 1.3 | REACTOME NETRIN1 SIGNALING | Genes involved in Netrin-1 signaling |
0.0 | 1.5 | REACTOME EFFECTS OF PIP2 HYDROLYSIS | Genes involved in Effects of PIP2 hydrolysis |
0.0 | 1.1 | REACTOME SIGNALING BY HIPPO | Genes involved in Signaling by Hippo |
0.0 | 0.6 | REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS | Genes involved in Synthesis of substrates in N-glycan biosythesis |
0.0 | 1.2 | REACTOME METAL ION SLC TRANSPORTERS | Genes involved in Metal ion SLC transporters |
0.0 | 1.2 | REACTOME MYOGENESIS | Genes involved in Myogenesis |
0.0 | 1.1 | REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS | Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits |
0.0 | 3.3 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
0.0 | 1.9 | REACTOME G ALPHA Q SIGNALLING EVENTS | Genes involved in G alpha (q) signalling events |
0.0 | 0.4 | REACTOME GROWTH HORMONE RECEPTOR SIGNALING | Genes involved in Growth hormone receptor signaling |
0.0 | 0.9 | REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES | Genes involved in Antiviral mechanism by IFN-stimulated genes |
0.0 | 1.3 | REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |