avrg: GSE58827: Dynamics of the Mouse Liver
Gene Symbol | Gene ID | Gene Info |
---|---|---|
Gli1
|
ENSMUSG00000025407.6 | GLI-Kruppel family member GLI1 |
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Gli1 | mm10_v2_chr10_-_127341583_127341614 | 0.02 | 9.1e-01 | Click! |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.7 | 2.0 | GO:0010751 | negative regulation of nitric oxide mediated signal transduction(GO:0010751) |
0.3 | 1.4 | GO:0046898 | response to cycloheximide(GO:0046898) |
0.3 | 0.8 | GO:1904980 | regulation of endosome organization(GO:1904978) positive regulation of endosome organization(GO:1904980) |
0.2 | 0.8 | GO:0061146 | Peyer's patch morphogenesis(GO:0061146) |
0.2 | 0.6 | GO:0045226 | extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379) |
0.2 | 1.4 | GO:0045196 | establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200) |
0.2 | 0.5 | GO:2000331 | regulation of terminal button organization(GO:2000331) |
0.2 | 0.6 | GO:0006015 | 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391) |
0.2 | 0.8 | GO:0002554 | serotonin secretion by platelet(GO:0002554) |
0.1 | 0.6 | GO:0021941 | negative regulation of cerebellar granule cell precursor proliferation(GO:0021941) |
0.1 | 0.6 | GO:0050960 | detection of temperature stimulus involved in thermoception(GO:0050960) response to capsazepine(GO:1901594) |
0.1 | 0.1 | GO:0000821 | regulation of arginine metabolic process(GO:0000821) |
0.1 | 0.6 | GO:0051697 | protein delipidation(GO:0051697) |
0.1 | 0.9 | GO:2000672 | negative regulation of motor neuron apoptotic process(GO:2000672) |
0.1 | 2.2 | GO:0045605 | negative regulation of epidermal cell differentiation(GO:0045605) |
0.1 | 1.7 | GO:0046541 | saliva secretion(GO:0046541) |
0.1 | 0.8 | GO:2000491 | positive regulation of hepatic stellate cell activation(GO:2000491) |
0.1 | 0.4 | GO:0032290 | peripheral nervous system myelin formation(GO:0032290) |
0.1 | 0.5 | GO:0071985 | multivesicular body sorting pathway(GO:0071985) |
0.1 | 0.3 | GO:2001074 | negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302) regulation of metanephric ureteric bud development(GO:2001074) positive regulation of metanephric ureteric bud development(GO:2001076) |
0.1 | 0.7 | GO:1990035 | calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035) |
0.1 | 0.4 | GO:0051142 | regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142) |
0.1 | 0.3 | GO:0040030 | regulation of molecular function, epigenetic(GO:0040030) |
0.1 | 0.3 | GO:0031120 | snRNA pseudouridine synthesis(GO:0031120) |
0.1 | 0.4 | GO:1990481 | mRNA pseudouridine synthesis(GO:1990481) |
0.1 | 0.2 | GO:0070682 | proteasome regulatory particle assembly(GO:0070682) |
0.1 | 0.6 | GO:2000582 | positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582) |
0.1 | 0.3 | GO:0021993 | initiation of neural tube closure(GO:0021993) |
0.1 | 0.8 | GO:0006751 | glutathione catabolic process(GO:0006751) |
0.1 | 0.3 | GO:0034421 | post-translational protein acetylation(GO:0034421) |
0.1 | 1.3 | GO:0043486 | histone exchange(GO:0043486) |
0.1 | 0.5 | GO:2000348 | regulation of CD40 signaling pathway(GO:2000348) |
0.0 | 0.6 | GO:1901844 | regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844) negative regulation of relaxation of cardiac muscle(GO:1901898) |
0.0 | 1.1 | GO:0021516 | dorsal spinal cord development(GO:0021516) |
0.0 | 0.7 | GO:0046543 | development of secondary female sexual characteristics(GO:0046543) |
0.0 | 0.2 | GO:0002018 | renin-angiotensin regulation of aldosterone production(GO:0002018) |
0.0 | 0.1 | GO:0070375 | ERK5 cascade(GO:0070375) |
0.0 | 0.2 | GO:0010760 | negative regulation of macrophage chemotaxis(GO:0010760) |
0.0 | 1.0 | GO:1900017 | positive regulation of cytokine production involved in inflammatory response(GO:1900017) |
0.0 | 0.7 | GO:0051574 | positive regulation of histone H3-K9 methylation(GO:0051574) |
0.0 | 1.2 | GO:0015701 | bicarbonate transport(GO:0015701) |
0.0 | 0.3 | GO:0007296 | vitellogenesis(GO:0007296) |
0.0 | 0.3 | GO:1900262 | regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264) |
0.0 | 0.2 | GO:0045876 | positive regulation of sister chromatid cohesion(GO:0045876) |
0.0 | 0.6 | GO:1903818 | positive regulation of voltage-gated potassium channel activity(GO:1903818) |
0.0 | 0.4 | GO:0034625 | fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) |
0.0 | 0.4 | GO:0034501 | protein localization to kinetochore(GO:0034501) |
0.0 | 2.5 | GO:1902017 | regulation of cilium assembly(GO:1902017) |
0.0 | 0.1 | GO:0031118 | rRNA pseudouridine synthesis(GO:0031118) |
0.0 | 0.6 | GO:1903861 | positive regulation of dendrite extension(GO:1903861) |
0.0 | 0.3 | GO:0043568 | positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568) |
0.0 | 0.1 | GO:0060709 | glycogen cell differentiation involved in embryonic placenta development(GO:0060709) |
0.0 | 0.4 | GO:0060272 | embryonic skeletal joint morphogenesis(GO:0060272) |
0.0 | 0.2 | GO:0051490 | negative regulation of filopodium assembly(GO:0051490) |
0.0 | 0.6 | GO:0097320 | membrane tubulation(GO:0097320) |
0.0 | 0.1 | GO:0061086 | negative regulation of histone H3-K27 methylation(GO:0061086) |
0.0 | 0.2 | GO:1900827 | positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827) |
0.0 | 0.1 | GO:0045204 | MAPK export from nucleus(GO:0045204) |
0.0 | 0.1 | GO:0042414 | epinephrine metabolic process(GO:0042414) |
0.0 | 0.1 | GO:0001180 | transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180) |
0.0 | 0.4 | GO:0071108 | protein K48-linked deubiquitination(GO:0071108) |
0.0 | 0.1 | GO:1902775 | mitochondrial large ribosomal subunit assembly(GO:1902775) |
0.0 | 0.4 | GO:1903077 | negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376) |
0.0 | 0.7 | GO:0007520 | myoblast fusion(GO:0007520) |
0.0 | 0.1 | GO:0045162 | clustering of voltage-gated sodium channels(GO:0045162) |
0.0 | 0.1 | GO:0050917 | sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917) |
0.0 | 0.1 | GO:0040032 | post-embryonic body morphogenesis(GO:0040032) |
0.0 | 0.1 | GO:1901097 | negative regulation of autophagosome maturation(GO:1901097) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 0.8 | GO:0030312 | external encapsulating structure(GO:0030312) |
0.2 | 2.7 | GO:0097539 | ciliary transition fiber(GO:0097539) |
0.2 | 0.7 | GO:0097058 | CRLF-CLCF1 complex(GO:0097058) |
0.2 | 0.6 | GO:0002189 | ribose phosphate diphosphokinase complex(GO:0002189) |
0.1 | 1.4 | GO:0097136 | Bcl-2 family protein complex(GO:0097136) |
0.1 | 0.5 | GO:0032585 | multivesicular body membrane(GO:0032585) |
0.1 | 0.7 | GO:0005577 | fibrinogen complex(GO:0005577) |
0.1 | 0.3 | GO:0090661 | box H/ACA telomerase RNP complex(GO:0090661) |
0.0 | 1.3 | GO:0097228 | sperm principal piece(GO:0097228) |
0.0 | 0.6 | GO:1904115 | axon cytoplasm(GO:1904115) |
0.0 | 0.4 | GO:0000940 | condensed chromosome outer kinetochore(GO:0000940) |
0.0 | 0.2 | GO:0000798 | nuclear cohesin complex(GO:0000798) |
0.0 | 0.3 | GO:0031390 | Ctf18 RFC-like complex(GO:0031390) |
0.0 | 0.8 | GO:0030132 | clathrin coat of coated pit(GO:0030132) |
0.0 | 0.2 | GO:0071203 | WASH complex(GO:0071203) |
0.0 | 2.7 | GO:0014704 | intercalated disc(GO:0014704) |
0.0 | 0.2 | GO:0031466 | Cul5-RING ubiquitin ligase complex(GO:0031466) |
0.0 | 0.4 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
0.0 | 0.7 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
0.0 | 0.8 | GO:0060077 | inhibitory synapse(GO:0060077) |
0.0 | 0.6 | GO:0001891 | phagocytic cup(GO:0001891) |
0.0 | 0.4 | GO:0016580 | Sin3 complex(GO:0016580) |
0.0 | 0.1 | GO:0031595 | nuclear proteasome complex(GO:0031595) |
0.0 | 0.2 | GO:0008540 | proteasome regulatory particle, base subcomplex(GO:0008540) |
0.0 | 0.6 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
0.0 | 0.1 | GO:0045009 | melanosome membrane(GO:0033162) chitosome(GO:0045009) |
0.0 | 0.3 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
0.0 | 0.1 | GO:0000120 | RNA polymerase I transcription factor complex(GO:0000120) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 1.4 | GO:0016286 | small conductance calcium-activated potassium channel activity(GO:0016286) |
0.2 | 0.6 | GO:0005330 | dopamine:sodium symporter activity(GO:0005330) |
0.2 | 0.7 | GO:0070052 | collagen V binding(GO:0070052) |
0.2 | 0.8 | GO:0043812 | phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812) |
0.2 | 0.5 | GO:0008192 | RNA guanylyltransferase activity(GO:0008192) |
0.2 | 0.6 | GO:0004749 | ribose phosphate diphosphokinase activity(GO:0004749) |
0.2 | 0.8 | GO:0003839 | gamma-glutamylcyclotransferase activity(GO:0003839) |
0.2 | 0.6 | GO:0050501 | hyaluronan synthase activity(GO:0050501) |
0.2 | 0.8 | GO:0004966 | galanin receptor activity(GO:0004966) |
0.1 | 1.4 | GO:0051434 | BH3 domain binding(GO:0051434) |
0.1 | 2.0 | GO:0030235 | nitric-oxide synthase regulator activity(GO:0030235) |
0.1 | 0.8 | GO:0035381 | extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381) |
0.1 | 0.6 | GO:0097603 | temperature-gated ion channel activity(GO:0097603) |
0.1 | 0.4 | GO:0043515 | kinetochore binding(GO:0043515) |
0.1 | 0.7 | GO:0005127 | ciliary neurotrophic factor receptor binding(GO:0005127) |
0.1 | 1.2 | GO:0008510 | sodium:bicarbonate symporter activity(GO:0008510) |
0.1 | 0.3 | GO:0031781 | melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782) |
0.1 | 0.3 | GO:0030280 | structural constituent of epidermis(GO:0030280) |
0.1 | 0.3 | GO:0004994 | somatostatin receptor activity(GO:0004994) |
0.1 | 0.3 | GO:0003986 | acetyl-CoA hydrolase activity(GO:0003986) |
0.0 | 0.3 | GO:0034513 | box H/ACA snoRNA binding(GO:0034513) |
0.0 | 0.3 | GO:0044729 | hemi-methylated DNA-binding(GO:0044729) |
0.0 | 0.3 | GO:0005111 | type 2 fibroblast growth factor receptor binding(GO:0005111) |
0.0 | 0.5 | GO:0009982 | pseudouridine synthase activity(GO:0009982) |
0.0 | 0.4 | GO:0102336 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
0.0 | 1.7 | GO:0043027 | cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) |
0.0 | 0.1 | GO:0031751 | D4 dopamine receptor binding(GO:0031751) |
0.0 | 0.1 | GO:0034617 | tetrahydrobiopterin binding(GO:0034617) |
0.0 | 0.4 | GO:0008349 | MAP kinase kinase kinase kinase activity(GO:0008349) |
0.0 | 2.9 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
0.0 | 0.3 | GO:0005522 | profilin binding(GO:0005522) |
0.0 | 1.4 | GO:0048487 | beta-tubulin binding(GO:0048487) |
0.0 | 0.3 | GO:0033170 | DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170) |
0.0 | 0.7 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
0.0 | 1.3 | GO:0019212 | phosphatase inhibitor activity(GO:0019212) |
0.0 | 0.5 | GO:0042043 | neurexin family protein binding(GO:0042043) |
0.0 | 2.4 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
0.0 | 0.1 | GO:0004724 | magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724) |
0.0 | 0.2 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
0.0 | 0.5 | GO:0070182 | DNA polymerase binding(GO:0070182) |
0.0 | 0.2 | GO:0015379 | potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820) |
0.0 | 0.5 | GO:0031489 | myosin V binding(GO:0031489) |
0.0 | 0.6 | GO:0004115 | 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) |
0.0 | 1.0 | GO:0005160 | transforming growth factor beta receptor binding(GO:0005160) |
0.0 | 0.6 | GO:0032452 | histone demethylase activity(GO:0032452) |
0.0 | 0.2 | GO:0048038 | quinone binding(GO:0048038) |
0.0 | 1.1 | GO:0004197 | cysteine-type endopeptidase activity(GO:0004197) |
0.0 | 0.1 | GO:0048185 | activin binding(GO:0048185) |
0.0 | 0.1 | GO:0086080 | protein binding involved in heterotypic cell-cell adhesion(GO:0086080) |
0.0 | 0.6 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
0.0 | 0.1 | GO:0004594 | pantothenate kinase activity(GO:0004594) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 1.4 | SA PROGRAMMED CELL DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
0.0 | 2.6 | PID PLK1 PATHWAY | PLK1 signaling events |
0.0 | 1.7 | SA B CELL RECEPTOR COMPLEXES | Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases. |
0.0 | 0.4 | PID TCR JNK PATHWAY | JNK signaling in the CD4+ TCR pathway |
0.0 | 0.7 | PID MAPK TRK PATHWAY | Trk receptor signaling mediated by the MAPK pathway |
0.0 | 0.8 | PID EPHB FWD PATHWAY | EPHB forward signaling |
0.0 | 0.7 | PID SYNDECAN 4 PATHWAY | Syndecan-4-mediated signaling events |
0.0 | 0.5 | PID BARD1 PATHWAY | BARD1 signaling events |
0.0 | 0.7 | PID PTP1B PATHWAY | Signaling events mediated by PTP1B |
0.0 | 4.4 | NABA SECRETED FACTORS | Genes encoding secreted soluble factors |
0.0 | 0.3 | PID INSULIN GLUCOSE PATHWAY | Insulin-mediated glucose transport |
0.0 | 0.5 | NABA BASEMENT MEMBRANES | Genes encoding structural components of basement membranes |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 0.8 | REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS | Genes involved in Elevation of cytosolic Ca2+ levels |
0.1 | 1.4 | REACTOME INFLAMMASOMES | Genes involved in Inflammasomes |
0.1 | 1.8 | REACTOME ERK MAPK TARGETS | Genes involved in ERK/MAPK targets |
0.0 | 0.5 | REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY | Genes involved in Regulation of the Fanconi anemia pathway |
0.0 | 0.6 | REACTOME HYALURONAN METABOLISM | Genes involved in Hyaluronan metabolism |
0.0 | 0.7 | REACTOME ACTIVATION OF BH3 ONLY PROTEINS | Genes involved in Activation of BH3-only proteins |
0.0 | 1.0 | REACTOME MYOGENESIS | Genes involved in Myogenesis |
0.0 | 0.6 | REACTOME DARPP 32 EVENTS | Genes involved in DARPP-32 events |
0.0 | 0.8 | REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE | Genes involved in Synthesis of PIPs at the plasma membrane |
0.0 | 0.3 | REACTOME PHOSPHORYLATION OF THE APC C | Genes involved in Phosphorylation of the APC/C |
0.0 | 0.4 | REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS | Genes involved in Synthesis of very long-chain fatty acyl-CoAs |
0.0 | 0.1 | REACTOME PLATELET CALCIUM HOMEOSTASIS | Genes involved in Platelet calcium homeostasis |