avrg: GSE58827: Dynamics of the Mouse Liver
Gene Symbol | Gene ID | Gene Info |
---|---|---|
Klf15
|
ENSMUSG00000030087.5 | Kruppel-like factor 15 |
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Klf15 | mm10_v2_chr6_+_90462562_90462587 | 0.65 | 1.9e-05 | Click! |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.7 | 5.1 | GO:0045014 | carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014) |
1.4 | 4.3 | GO:0048627 | myoblast development(GO:0048627) |
0.8 | 2.5 | GO:0010133 | proline catabolic process to glutamate(GO:0010133) |
0.8 | 3.3 | GO:0090472 | dibasic protein processing(GO:0090472) |
0.8 | 3.2 | GO:0007621 | negative regulation of female receptivity(GO:0007621) |
0.7 | 2.1 | GO:1904760 | myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760) |
0.6 | 5.1 | GO:0006004 | fucose metabolic process(GO:0006004) |
0.6 | 1.8 | GO:1905051 | regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053) |
0.6 | 4.0 | GO:0016480 | negative regulation of transcription from RNA polymerase III promoter(GO:0016480) |
0.4 | 1.3 | GO:0061300 | cerebellum vasculature development(GO:0061300) |
0.4 | 3.0 | GO:0051725 | protein de-ADP-ribosylation(GO:0051725) |
0.4 | 1.2 | GO:0097101 | arterial endothelial cell fate commitment(GO:0060844) blood vessel endothelial cell fate commitment(GO:0060846) Notch signaling pathway involved in arterial endothelial cell fate commitment(GO:0060853) blood vessel endothelial cell fate specification(GO:0097101) |
0.3 | 1.4 | GO:2000383 | regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384) |
0.3 | 1.3 | GO:0002023 | reduction of food intake in response to dietary excess(GO:0002023) |
0.3 | 0.9 | GO:0090285 | negative regulation of protein glycosylation in Golgi(GO:0090285) |
0.3 | 1.2 | GO:0002302 | CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302) |
0.3 | 2.7 | GO:0060267 | positive regulation of respiratory burst(GO:0060267) |
0.3 | 0.8 | GO:0071707 | immunoglobulin heavy chain V-D-J recombination(GO:0071707) |
0.3 | 1.1 | GO:0071596 | ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596) |
0.2 | 0.2 | GO:0090283 | regulation of protein glycosylation in Golgi(GO:0090283) |
0.2 | 1.2 | GO:0021914 | negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914) |
0.2 | 0.7 | GO:1905223 | epicardium morphogenesis(GO:1905223) |
0.2 | 1.1 | GO:0033092 | positive regulation of immature T cell proliferation in thymus(GO:0033092) |
0.2 | 1.2 | GO:0098963 | dendritic transport of ribonucleoprotein complex(GO:0098961) dendritic transport of messenger ribonucleoprotein complex(GO:0098963) anterograde dendritic transport of messenger ribonucleoprotein complex(GO:0098964) |
0.2 | 3.8 | GO:0072189 | ureter development(GO:0072189) |
0.2 | 2.9 | GO:0006957 | complement activation, alternative pathway(GO:0006957) |
0.2 | 0.5 | GO:0030573 | bile acid catabolic process(GO:0030573) |
0.2 | 1.4 | GO:0036444 | calcium ion transmembrane import into mitochondrion(GO:0036444) |
0.2 | 1.0 | GO:0060596 | mammary placode formation(GO:0060596) |
0.2 | 2.5 | GO:0030322 | stabilization of membrane potential(GO:0030322) |
0.2 | 1.1 | GO:0010991 | regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991) |
0.2 | 1.7 | GO:2000535 | entry of bacterium into host cell(GO:0035635) regulation of entry of bacterium into host cell(GO:2000535) |
0.2 | 4.0 | GO:0016339 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339) |
0.1 | 5.4 | GO:0010758 | regulation of macrophage chemotaxis(GO:0010758) |
0.1 | 1.3 | GO:0001574 | ganglioside biosynthetic process(GO:0001574) |
0.1 | 0.4 | GO:0018894 | dibenzo-p-dioxin metabolic process(GO:0018894) endothelial cell-cell adhesion(GO:0071603) |
0.1 | 0.4 | GO:0072277 | cell migration involved in vasculogenesis(GO:0035441) metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277) |
0.1 | 0.7 | GO:0045716 | positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716) |
0.1 | 1.6 | GO:0045607 | regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980) |
0.1 | 1.3 | GO:0061366 | behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368) |
0.1 | 0.5 | GO:1900740 | regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740) |
0.1 | 0.5 | GO:0072272 | proximal/distal pattern formation involved in metanephric nephron development(GO:0072272) |
0.1 | 0.7 | GO:0051684 | maintenance of Golgi location(GO:0051684) |
0.1 | 0.5 | GO:0035106 | operant conditioning(GO:0035106) |
0.1 | 0.4 | GO:0021998 | neural plate mediolateral regionalization(GO:0021998) mesoderm structural organization(GO:0048338) paraxial mesoderm structural organization(GO:0048352) regulation of cardiac ventricle development(GO:1904412) positive regulation of cardiac ventricle development(GO:1904414) |
0.1 | 1.3 | GO:0051045 | negative regulation of membrane protein ectodomain proteolysis(GO:0051045) |
0.1 | 0.4 | GO:1902868 | cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871) |
0.1 | 1.1 | GO:0070345 | negative regulation of fat cell proliferation(GO:0070345) |
0.1 | 2.5 | GO:0006491 | N-glycan processing(GO:0006491) |
0.1 | 0.7 | GO:0042276 | error-prone translesion synthesis(GO:0042276) |
0.1 | 1.0 | GO:0090043 | regulation of tubulin deacetylation(GO:0090043) |
0.1 | 0.3 | GO:2001184 | positive regulation of interleukin-12 secretion(GO:2001184) |
0.1 | 0.3 | GO:0000715 | nucleotide-excision repair, DNA damage recognition(GO:0000715) |
0.1 | 0.5 | GO:0007217 | tachykinin receptor signaling pathway(GO:0007217) |
0.1 | 1.1 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
0.1 | 0.4 | GO:0043152 | induction of bacterial agglutination(GO:0043152) |
0.1 | 0.6 | GO:1900170 | negative regulation of glucocorticoid mediated signaling pathway(GO:1900170) |
0.1 | 0.5 | GO:0033140 | negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140) |
0.1 | 0.4 | GO:0072137 | cell migration involved in endocardial cushion formation(GO:0003273) condensed mesenchymal cell proliferation(GO:0072137) |
0.1 | 0.5 | GO:0061086 | negative regulation of histone H3-K27 methylation(GO:0061086) |
0.1 | 3.2 | GO:0019373 | epoxygenase P450 pathway(GO:0019373) |
0.1 | 0.8 | GO:0051561 | positive regulation of mitochondrial calcium ion concentration(GO:0051561) |
0.1 | 0.8 | GO:0043587 | tongue morphogenesis(GO:0043587) |
0.1 | 0.4 | GO:0060598 | dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis(GO:0060598) |
0.1 | 1.9 | GO:0042297 | vocal learning(GO:0042297) imitative learning(GO:0098596) |
0.1 | 0.4 | GO:0045358 | N-terminal peptidyl-lysine acetylation(GO:0018076) negative regulation of interferon-beta biosynthetic process(GO:0045358) |
0.1 | 1.3 | GO:0071236 | cellular response to antibiotic(GO:0071236) |
0.1 | 0.4 | GO:0010726 | positive regulation of hydrogen peroxide metabolic process(GO:0010726) |
0.1 | 2.3 | GO:0006691 | leukotriene metabolic process(GO:0006691) |
0.1 | 1.8 | GO:0030325 | adrenal gland development(GO:0030325) |
0.1 | 1.0 | GO:0021902 | commitment of neuronal cell to specific neuron type in forebrain(GO:0021902) |
0.1 | 0.8 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
0.1 | 1.3 | GO:0038063 | collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) |
0.1 | 0.6 | GO:0071321 | cellular response to cGMP(GO:0071321) potassium ion import across plasma membrane(GO:1990573) |
0.1 | 0.2 | GO:0036092 | phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092) regulation of zinc ion transport(GO:0071579) |
0.1 | 2.5 | GO:0061099 | negative regulation of protein tyrosine kinase activity(GO:0061099) |
0.1 | 0.5 | GO:0014053 | negative regulation of gamma-aminobutyric acid secretion(GO:0014053) |
0.1 | 0.7 | GO:0035280 | miRNA loading onto RISC involved in gene silencing by miRNA(GO:0035280) |
0.1 | 3.2 | GO:0036075 | endochondral ossification(GO:0001958) replacement ossification(GO:0036075) |
0.1 | 0.7 | GO:0035507 | regulation of myosin-light-chain-phosphatase activity(GO:0035507) |
0.1 | 1.0 | GO:0048387 | negative regulation of retinoic acid receptor signaling pathway(GO:0048387) |
0.1 | 1.3 | GO:0031987 | locomotion involved in locomotory behavior(GO:0031987) |
0.1 | 0.3 | GO:0051012 | microtubule sliding(GO:0051012) |
0.1 | 1.0 | GO:0070050 | neuron cellular homeostasis(GO:0070050) |
0.1 | 0.5 | GO:0070294 | renal sodium ion absorption(GO:0070294) |
0.1 | 0.1 | GO:0021913 | regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913) |
0.1 | 0.8 | GO:2000507 | positive regulation of energy homeostasis(GO:2000507) |
0.1 | 0.4 | GO:0045200 | establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200) |
0.1 | 0.5 | GO:0045162 | clustering of voltage-gated sodium channels(GO:0045162) |
0.1 | 0.5 | GO:0061002 | negative regulation of dendritic spine morphogenesis(GO:0061002) |
0.1 | 0.2 | GO:1901492 | positive regulation of lymphangiogenesis(GO:1901492) |
0.1 | 0.5 | GO:0098532 | histone H3-K27 trimethylation(GO:0098532) |
0.1 | 0.2 | GO:0003430 | growth plate cartilage chondrocyte growth(GO:0003430) |
0.1 | 0.3 | GO:0072368 | regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter(GO:0072368) |
0.1 | 0.7 | GO:0002862 | negative regulation of inflammatory response to antigenic stimulus(GO:0002862) |
0.1 | 1.0 | GO:0032927 | positive regulation of activin receptor signaling pathway(GO:0032927) |
0.0 | 1.2 | GO:0045671 | negative regulation of osteoclast differentiation(GO:0045671) |
0.0 | 0.7 | GO:0032780 | negative regulation of ATPase activity(GO:0032780) |
0.0 | 0.3 | GO:0051534 | negative regulation of NFAT protein import into nucleus(GO:0051534) |
0.0 | 0.1 | GO:1905077 | negative regulation of interleukin-17 secretion(GO:1905077) |
0.0 | 0.2 | GO:0016584 | nucleosome positioning(GO:0016584) |
0.0 | 1.0 | GO:0042347 | negative regulation of NF-kappaB import into nucleus(GO:0042347) |
0.0 | 0.2 | GO:0060019 | radial glial cell differentiation(GO:0060019) |
0.0 | 0.6 | GO:2001223 | negative regulation of neuron migration(GO:2001223) |
0.0 | 0.3 | GO:0033153 | somatic diversification of T cell receptor genes(GO:0002568) somatic recombination of T cell receptor gene segments(GO:0002681) T cell receptor V(D)J recombination(GO:0033153) |
0.0 | 0.4 | GO:0033353 | S-adenosylmethionine cycle(GO:0033353) |
0.0 | 1.4 | GO:0015986 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
0.0 | 0.9 | GO:0051044 | regulation of membrane protein ectodomain proteolysis(GO:0051043) positive regulation of membrane protein ectodomain proteolysis(GO:0051044) |
0.0 | 0.0 | GO:0097168 | mesenchymal stem cell proliferation(GO:0097168) regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462) |
0.0 | 2.2 | GO:0007520 | myoblast fusion(GO:0007520) |
0.0 | 0.8 | GO:0007190 | activation of adenylate cyclase activity(GO:0007190) |
0.0 | 0.4 | GO:2000303 | regulation of ceramide biosynthetic process(GO:2000303) |
0.0 | 0.1 | GO:0007161 | calcium-independent cell-matrix adhesion(GO:0007161) |
0.0 | 1.7 | GO:0008333 | endosome to lysosome transport(GO:0008333) |
0.0 | 0.8 | GO:0030574 | collagen catabolic process(GO:0030574) |
0.0 | 0.2 | GO:0016338 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338) |
0.0 | 0.3 | GO:2000301 | negative regulation of synaptic vesicle exocytosis(GO:2000301) |
0.0 | 1.1 | GO:0061036 | positive regulation of cartilage development(GO:0061036) |
0.0 | 0.3 | GO:1990118 | sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118) |
0.0 | 2.4 | GO:0042147 | retrograde transport, endosome to Golgi(GO:0042147) |
0.0 | 0.9 | GO:0071108 | protein K48-linked deubiquitination(GO:0071108) |
0.0 | 0.3 | GO:0071285 | cellular response to lithium ion(GO:0071285) |
0.0 | 0.8 | GO:0009303 | rRNA transcription(GO:0009303) |
0.0 | 0.3 | GO:0051151 | negative regulation of smooth muscle cell differentiation(GO:0051151) |
0.0 | 0.4 | GO:0043011 | myeloid dendritic cell differentiation(GO:0043011) |
0.0 | 0.1 | GO:0032667 | interleukin-23 production(GO:0032627) regulation of interleukin-23 production(GO:0032667) |
0.0 | 0.3 | GO:1900383 | regulation of synaptic plasticity by receptor localization to synapse(GO:1900383) |
0.0 | 0.6 | GO:1902236 | retrograde protein transport, ER to cytosol(GO:0030970) negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236) |
0.0 | 0.1 | GO:0046946 | hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947) |
0.0 | 0.8 | GO:0034243 | regulation of transcription elongation from RNA polymerase II promoter(GO:0034243) |
0.0 | 0.2 | GO:0036065 | fucosylation(GO:0036065) |
0.0 | 0.1 | GO:0006369 | termination of RNA polymerase II transcription(GO:0006369) |
0.0 | 0.5 | GO:0050908 | detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962) |
0.0 | 0.3 | GO:1903818 | positive regulation of voltage-gated potassium channel activity(GO:1903818) |
0.0 | 0.1 | GO:0018242 | protein O-linked glycosylation via serine(GO:0018242) |
0.0 | 0.4 | GO:1900452 | regulation of long term synaptic depression(GO:1900452) |
0.0 | 0.5 | GO:0032012 | ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012) |
0.0 | 0.5 | GO:0018345 | protein palmitoylation(GO:0018345) |
0.0 | 0.4 | GO:0043486 | histone exchange(GO:0043486) |
0.0 | 0.3 | GO:0021794 | thalamus development(GO:0021794) |
0.0 | 0.3 | GO:0032287 | peripheral nervous system myelin maintenance(GO:0032287) |
0.0 | 0.2 | GO:0035878 | nail development(GO:0035878) |
0.0 | 0.4 | GO:0051639 | actin filament network formation(GO:0051639) |
0.0 | 0.8 | GO:0035019 | somatic stem cell population maintenance(GO:0035019) |
0.0 | 0.1 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
0.0 | 0.6 | GO:0032981 | NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031) |
0.0 | 0.2 | GO:0098743 | cell aggregation(GO:0098743) |
0.0 | 0.7 | GO:0017145 | stem cell division(GO:0017145) |
0.0 | 0.7 | GO:0033209 | tumor necrosis factor-mediated signaling pathway(GO:0033209) |
0.0 | 0.1 | GO:0009597 | detection of virus(GO:0009597) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 1.3 | GO:0042720 | mitochondrial inner membrane peptidase complex(GO:0042720) |
0.3 | 1.4 | GO:1990246 | uniplex complex(GO:1990246) |
0.3 | 2.9 | GO:0005579 | membrane attack complex(GO:0005579) |
0.2 | 1.0 | GO:0043293 | apoptosome(GO:0043293) |
0.2 | 1.7 | GO:0070695 | FHF complex(GO:0070695) |
0.2 | 3.7 | GO:0012510 | trans-Golgi network transport vesicle membrane(GO:0012510) |
0.2 | 1.3 | GO:0098642 | collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651) |
0.2 | 0.6 | GO:0098855 | HCN channel complex(GO:0098855) |
0.2 | 1.7 | GO:0032584 | growth cone membrane(GO:0032584) |
0.1 | 0.6 | GO:0000839 | Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839) |
0.1 | 0.9 | GO:0097413 | Lewy body(GO:0097413) |
0.1 | 0.7 | GO:0016035 | zeta DNA polymerase complex(GO:0016035) |
0.1 | 3.9 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
0.1 | 0.5 | GO:0038039 | G-protein coupled receptor heterodimeric complex(GO:0038039) |
0.1 | 0.9 | GO:0000137 | Golgi cis cisterna(GO:0000137) |
0.1 | 1.7 | GO:0000124 | SAGA complex(GO:0000124) |
0.1 | 1.4 | GO:0000276 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) |
0.1 | 0.8 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
0.1 | 0.3 | GO:0071942 | XPC complex(GO:0071942) |
0.1 | 0.7 | GO:0070578 | RISC-loading complex(GO:0070578) |
0.1 | 0.6 | GO:0000127 | transcription factor TFIIIC complex(GO:0000127) |
0.1 | 0.5 | GO:0008091 | spectrin(GO:0008091) |
0.1 | 0.3 | GO:0034388 | Pwp2p-containing subcomplex of 90S preribosome(GO:0034388) |
0.1 | 0.8 | GO:0031011 | Ino80 complex(GO:0031011) |
0.1 | 0.8 | GO:0005662 | DNA replication factor A complex(GO:0005662) |
0.0 | 1.2 | GO:1990124 | messenger ribonucleoprotein complex(GO:1990124) |
0.0 | 0.4 | GO:0005577 | fibrinogen complex(GO:0005577) |
0.0 | 2.8 | GO:0005793 | endoplasmic reticulum-Golgi intermediate compartment(GO:0005793) |
0.0 | 1.4 | GO:0055038 | recycling endosome membrane(GO:0055038) |
0.0 | 2.4 | GO:0045335 | phagocytic vesicle(GO:0045335) |
0.0 | 0.3 | GO:0035749 | myelin sheath adaxonal region(GO:0035749) |
0.0 | 0.3 | GO:0032937 | SREBP-SCAP-Insig complex(GO:0032937) |
0.0 | 1.1 | GO:0034364 | high-density lipoprotein particle(GO:0034364) |
0.0 | 0.8 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
0.0 | 0.4 | GO:0000940 | condensed chromosome outer kinetochore(GO:0000940) |
0.0 | 1.2 | GO:0031901 | early endosome membrane(GO:0031901) |
0.0 | 1.5 | GO:0001772 | immunological synapse(GO:0001772) |
0.0 | 0.8 | GO:0097440 | apical dendrite(GO:0097440) |
0.0 | 2.7 | GO:0030175 | filopodium(GO:0030175) |
0.0 | 1.6 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
0.0 | 1.3 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
0.0 | 0.5 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
0.0 | 1.8 | GO:0032587 | ruffle membrane(GO:0032587) |
0.0 | 1.4 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
0.0 | 1.0 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
0.0 | 2.1 | GO:0001650 | fibrillar center(GO:0001650) |
0.0 | 0.3 | GO:0030673 | axolemma(GO:0030673) |
0.0 | 0.6 | GO:0030964 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
0.0 | 4.1 | GO:0009897 | external side of plasma membrane(GO:0009897) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.3 | 5.1 | GO:0042806 | fucose binding(GO:0042806) |
1.1 | 3.2 | GO:0031752 | D4 dopamine receptor binding(GO:0031751) D5 dopamine receptor binding(GO:0031752) |
0.3 | 2.8 | GO:0004571 | mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) |
0.2 | 3.3 | GO:0048406 | nerve growth factor binding(GO:0048406) |
0.2 | 1.3 | GO:0008597 | calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597) |
0.2 | 2.9 | GO:0019841 | retinol binding(GO:0019841) |
0.2 | 0.8 | GO:0032422 | purine-rich negative regulatory element binding(GO:0032422) |
0.2 | 0.6 | GO:0004968 | gonadotropin-releasing hormone receptor activity(GO:0004968) |
0.2 | 2.5 | GO:0022841 | potassium ion leak channel activity(GO:0022841) |
0.1 | 1.3 | GO:0001665 | alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665) |
0.1 | 1.2 | GO:0045545 | syndecan binding(GO:0045545) |
0.1 | 1.3 | GO:0047498 | calcium-dependent phospholipase A2 activity(GO:0047498) |
0.1 | 0.5 | GO:0004703 | G-protein coupled receptor kinase activity(GO:0004703) |
0.1 | 0.6 | GO:0038049 | glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051) |
0.1 | 0.7 | GO:1990829 | C-rich single-stranded DNA binding(GO:1990829) |
0.1 | 2.5 | GO:0004029 | aldehyde dehydrogenase (NAD) activity(GO:0004029) |
0.1 | 1.4 | GO:0070097 | delta-catenin binding(GO:0070097) |
0.1 | 1.5 | GO:0008349 | MAP kinase kinase kinase kinase activity(GO:0008349) |
0.1 | 1.1 | GO:0097027 | ubiquitin-protein transferase activator activity(GO:0097027) |
0.1 | 0.6 | GO:0005222 | intracellular cAMP activated cation channel activity(GO:0005222) |
0.1 | 1.1 | GO:0015093 | ferrous iron transmembrane transporter activity(GO:0015093) |
0.1 | 0.5 | GO:0004965 | G-protein coupled GABA receptor activity(GO:0004965) |
0.1 | 0.4 | GO:0038085 | vascular endothelial growth factor binding(GO:0038085) |
0.1 | 3.2 | GO:0008392 | arachidonic acid epoxygenase activity(GO:0008392) |
0.1 | 0.7 | GO:0034711 | inhibin binding(GO:0034711) |
0.1 | 0.7 | GO:0005114 | type II transforming growth factor beta receptor binding(GO:0005114) |
0.1 | 1.2 | GO:0030957 | Tat protein binding(GO:0030957) |
0.1 | 0.9 | GO:0019855 | calcium channel inhibitor activity(GO:0019855) |
0.1 | 0.2 | GO:0017150 | tRNA dihydrouridine synthase activity(GO:0017150) |
0.1 | 0.8 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) |
0.1 | 0.3 | GO:0033188 | sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493) |
0.1 | 0.4 | GO:0008467 | [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467) |
0.1 | 1.3 | GO:0008327 | methyl-CpG binding(GO:0008327) |
0.1 | 1.1 | GO:0070412 | R-SMAD binding(GO:0070412) |
0.1 | 0.4 | GO:0016802 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
0.1 | 0.8 | GO:0004016 | adenylate cyclase activity(GO:0004016) |
0.0 | 2.8 | GO:0001205 | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205) |
0.0 | 0.4 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
0.0 | 0.4 | GO:0001093 | TFIIB-class transcription factor binding(GO:0001093) |
0.0 | 1.6 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
0.0 | 1.6 | GO:0005246 | calcium channel regulator activity(GO:0005246) |
0.0 | 0.5 | GO:0000182 | rDNA binding(GO:0000182) |
0.0 | 2.6 | GO:0004712 | protein serine/threonine/tyrosine kinase activity(GO:0004712) |
0.0 | 0.4 | GO:0008494 | translation activator activity(GO:0008494) |
0.0 | 0.5 | GO:0008239 | dipeptidyl-peptidase activity(GO:0008239) |
0.0 | 0.8 | GO:0000400 | four-way junction DNA binding(GO:0000400) |
0.0 | 0.4 | GO:0098821 | BMP receptor activity(GO:0098821) |
0.0 | 1.0 | GO:0070410 | co-SMAD binding(GO:0070410) |
0.0 | 2.4 | GO:0019003 | GDP binding(GO:0019003) |
0.0 | 0.7 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
0.0 | 0.6 | GO:1904264 | ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264) |
0.0 | 0.9 | GO:0097602 | cullin family protein binding(GO:0097602) |
0.0 | 0.9 | GO:0070530 | K63-linked polyubiquitin binding(GO:0070530) |
0.0 | 0.5 | GO:0038191 | neuropilin binding(GO:0038191) |
0.0 | 0.3 | GO:0015386 | potassium:proton antiporter activity(GO:0015386) |
0.0 | 0.1 | GO:0046964 | 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964) |
0.0 | 1.9 | GO:0019213 | deacetylase activity(GO:0019213) |
0.0 | 0.9 | GO:0004683 | calmodulin-dependent protein kinase activity(GO:0004683) |
0.0 | 0.3 | GO:0004707 | MAP kinase activity(GO:0004707) |
0.0 | 0.2 | GO:0046920 | alpha-(1->3)-fucosyltransferase activity(GO:0046920) |
0.0 | 1.0 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
0.0 | 1.4 | GO:0005109 | frizzled binding(GO:0005109) |
0.0 | 1.2 | GO:0051019 | mitogen-activated protein kinase binding(GO:0051019) |
0.0 | 0.4 | GO:0016712 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712) aromatase activity(GO:0070330) |
0.0 | 1.9 | GO:0035064 | methylated histone binding(GO:0035064) |
0.0 | 0.7 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
0.0 | 1.0 | GO:0016922 | ligand-dependent nuclear receptor binding(GO:0016922) |
0.0 | 1.2 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
0.0 | 0.8 | GO:0017091 | AU-rich element binding(GO:0017091) |
0.0 | 0.7 | GO:0071889 | 14-3-3 protein binding(GO:0071889) |
0.0 | 0.5 | GO:0008395 | steroid hydroxylase activity(GO:0008395) |
0.0 | 0.2 | GO:0038132 | neuregulin binding(GO:0038132) |
0.0 | 0.1 | GO:0008475 | procollagen-lysine 5-dioxygenase activity(GO:0008475) |
0.0 | 1.2 | GO:0001102 | RNA polymerase II activating transcription factor binding(GO:0001102) |
0.0 | 0.7 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
0.0 | 0.7 | GO:0051059 | NF-kappaB binding(GO:0051059) |
0.0 | 0.7 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
0.0 | 0.3 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
0.0 | 0.1 | GO:0034450 | ubiquitin-ubiquitin ligase activity(GO:0034450) |
0.0 | 0.6 | GO:0004115 | 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) |
0.0 | 0.5 | GO:0019707 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707) |
0.0 | 2.6 | GO:0008083 | growth factor activity(GO:0008083) |
0.0 | 0.7 | GO:0003785 | actin monomer binding(GO:0003785) |
0.0 | 0.2 | GO:0035005 | 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005) |
0.0 | 0.3 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
0.0 | 1.1 | GO:0020037 | heme binding(GO:0020037) |
0.0 | 0.7 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
0.0 | 0.6 | GO:0008188 | neuropeptide receptor activity(GO:0008188) |
0.0 | 1.4 | GO:0015078 | hydrogen ion transmembrane transporter activity(GO:0015078) |
0.0 | 0.2 | GO:0003708 | retinoic acid receptor activity(GO:0003708) |
0.0 | 0.3 | GO:0031593 | polyubiquitin binding(GO:0031593) |
0.0 | 0.8 | GO:0030971 | receptor tyrosine kinase binding(GO:0030971) |
0.0 | 0.5 | GO:0030506 | ankyrin binding(GO:0030506) |
0.0 | 0.1 | GO:0051021 | GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022) |
0.0 | 0.9 | GO:0005249 | voltage-gated potassium channel activity(GO:0005249) |
0.0 | 0.3 | GO:0004385 | guanylate kinase activity(GO:0004385) |
0.0 | 0.3 | GO:0031434 | mitogen-activated protein kinase kinase binding(GO:0031434) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 5.0 | PID INTEGRIN5 PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
0.2 | 13.6 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
0.1 | 2.9 | PID NECTIN PATHWAY | Nectin adhesion pathway |
0.1 | 4.1 | PID LKB1 PATHWAY | LKB1 signaling events |
0.1 | 1.0 | PID ERBB NETWORK PATHWAY | ErbB receptor signaling network |
0.1 | 1.3 | PID ARF6 DOWNSTREAM PATHWAY | Arf6 downstream pathway |
0.0 | 2.4 | PID BMP PATHWAY | BMP receptor signaling |
0.0 | 4.9 | PID NOTCH PATHWAY | Notch signaling pathway |
0.0 | 0.8 | PID LPA4 PATHWAY | LPA4-mediated signaling events |
0.0 | 1.5 | PID TCR CALCIUM PATHWAY | Calcium signaling in the CD4+ TCR pathway |
0.0 | 1.9 | PID ARF6 TRAFFICKING PATHWAY | Arf6 trafficking events |
0.0 | 1.0 | PID SYNDECAN 4 PATHWAY | Syndecan-4-mediated signaling events |
0.0 | 1.2 | PID INTEGRIN3 PATHWAY | Beta3 integrin cell surface interactions |
0.0 | 2.8 | PID REG GR PATHWAY | Glucocorticoid receptor regulatory network |
0.0 | 2.4 | PID MTOR 4PATHWAY | mTOR signaling pathway |
0.0 | 0.7 | PID ALK1 PATHWAY | ALK1 signaling events |
0.0 | 1.3 | PID FANCONI PATHWAY | Fanconi anemia pathway |
0.0 | 0.2 | PID AVB3 INTEGRIN PATHWAY | Integrins in angiogenesis |
0.0 | 1.0 | PID A6B1 A6B4 INTEGRIN PATHWAY | a6b1 and a6b4 Integrin signaling |
0.0 | 0.4 | PID PI3K PLC TRK PATHWAY | Trk receptor signaling mediated by PI3K and PLC-gamma |
0.0 | 0.4 | PID ERBB2 ERBB3 PATHWAY | ErbB2/ErbB3 signaling events |
0.0 | 0.3 | PID PDGFRA PATHWAY | PDGFR-alpha signaling pathway |
0.0 | 1.2 | PID IL12 2PATHWAY | IL12-mediated signaling events |
0.0 | 1.4 | PID RB 1PATHWAY | Regulation of retinoblastoma protein |
0.0 | 1.2 | PID RAC1 REG PATHWAY | Regulation of RAC1 activity |
0.0 | 0.9 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
0.0 | 0.7 | PID MET PATHWAY | Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) |
0.0 | 0.3 | SA CASPASE CASCADE | Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade. |
0.0 | 0.2 | PID RETINOIC ACID PATHWAY | Retinoic acid receptors-mediated signaling |
0.0 | 0.4 | PID ALPHA SYNUCLEIN PATHWAY | Alpha-synuclein signaling |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 3.3 | REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS | Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins |
0.2 | 2.5 | REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS | Genes involved in Tandem pore domain potassium channels |
0.2 | 4.3 | REACTOME HS GAG DEGRADATION | Genes involved in HS-GAG degradation |
0.1 | 4.9 | REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS | Genes involved in Regulation of gene expression in beta cells |
0.1 | 1.2 | REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR | Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor |
0.1 | 0.9 | REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION | Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation |
0.1 | 2.9 | REACTOME COMPLEMENT CASCADE | Genes involved in Complement cascade |
0.1 | 1.1 | REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX | Genes involved in CDC6 association with the ORC:origin complex |
0.1 | 1.4 | REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING | Genes involved in Formation of ATP by chemiosmotic coupling |
0.1 | 3.2 | REACTOME DARPP 32 EVENTS | Genes involved in DARPP-32 events |
0.1 | 1.0 | REACTOME ENDOGENOUS STEROLS | Genes involved in Endogenous sterols |
0.1 | 2.4 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
0.1 | 1.3 | REACTOME ACYL CHAIN REMODELLING OF PI | Genes involved in Acyl chain remodelling of PI |
0.1 | 0.8 | REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB | Genes involved in PKA-mediated phosphorylation of CREB |
0.1 | 1.5 | REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING | Genes involved in Downregulation of TGF-beta receptor signaling |
0.1 | 1.1 | REACTOME HDL MEDIATED LIPID TRANSPORT | Genes involved in HDL-mediated lipid transport |
0.1 | 0.7 | REACTOME P2Y RECEPTORS | Genes involved in P2Y receptors |
0.0 | 0.8 | REACTOME MTORC1 MEDIATED SIGNALLING | Genes involved in mTORC1-mediated signalling |
0.0 | 0.8 | REACTOME SIGNALING BY NODAL | Genes involved in Signaling by NODAL |
0.0 | 0.7 | REACTOME DSCAM INTERACTIONS | Genes involved in DSCAM interactions |
0.0 | 1.0 | REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY | Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity |
0.0 | 0.5 | REACTOME ACTIVATION OF BH3 ONLY PROTEINS | Genes involved in Activation of BH3-only proteins |
0.0 | 0.4 | REACTOME DOWNSTREAM SIGNAL TRANSDUCTION | Genes involved in Downstream signal transduction |
0.0 | 0.4 | REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS | Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins |
0.0 | 0.4 | REACTOME CA DEPENDENT EVENTS | Genes involved in Ca-dependent events |
0.0 | 0.4 | REACTOME NOTCH HLH TRANSCRIPTION PATHWAY | Genes involved in Notch-HLH transcription pathway |
0.0 | 0.5 | REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |
0.0 | 0.3 | REACTOME SPRY REGULATION OF FGF SIGNALING | Genes involved in Spry regulation of FGF signaling |
0.0 | 1.2 | REACTOME VOLTAGE GATED POTASSIUM CHANNELS | Genes involved in Voltage gated Potassium channels |
0.0 | 1.7 | REACTOME NRAGE SIGNALS DEATH THROUGH JNK | Genes involved in NRAGE signals death through JNK |
0.0 | 0.4 | REACTOME SIGNALING BY BMP | Genes involved in Signaling by BMP |
0.0 | 0.6 | REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER | Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter |
0.0 | 1.5 | REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES | Genes involved in Antiviral mechanism by IFN-stimulated genes |
0.0 | 0.2 | REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE | Genes involved in Synthesis of PIPs at the late endosome membrane |
0.0 | 0.4 | REACTOME HS GAG BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
0.0 | 0.1 | REACTOME ACYL CHAIN REMODELLING OF PE | Genes involved in Acyl chain remodelling of PE |
0.0 | 0.7 | REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION | Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression |
0.0 | 0.3 | REACTOME FORMATION OF INCISION COMPLEX IN GG NER | Genes involved in Formation of incision complex in GG-NER |
0.0 | 0.2 | REACTOME FGFR4 LIGAND BINDING AND ACTIVATION | Genes involved in FGFR4 ligand binding and activation |
0.0 | 0.6 | REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S | Genes involved in Activation of Chaperone Genes by XBP1(S) |
0.0 | 0.4 | REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING | Genes involved in p75 NTR receptor-mediated signalling |
0.0 | 0.3 | REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS | Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus |
0.0 | 0.5 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
0.0 | 0.2 | REACTOME MEIOSIS | Genes involved in Meiosis |
0.0 | 2.5 | REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES | Genes involved in Metabolism of amino acids and derivatives |