avrg: GSE58827: Dynamics of the Mouse Liver
Gene Symbol | Gene ID | Gene Info |
---|---|---|
Prdm1
|
ENSMUSG00000038151.6 | PR domain containing 1, with ZNF domain |
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Prdm1 | mm10_v2_chr10_-_44458715_44458751 | -0.56 | 4.1e-04 | Click! |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
5.1 | 20.5 | GO:0009744 | fructose catabolic process(GO:0006001) response to sucrose(GO:0009744) response to disaccharide(GO:0034285) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) glycolytic process through fructose-1-phosphate(GO:0061625) |
3.3 | 10.0 | GO:1990166 | protein localization to site of double-strand break(GO:1990166) |
2.7 | 8.2 | GO:2000547 | regulation of dendritic cell dendrite assembly(GO:2000547) |
1.7 | 5.2 | GO:0019442 | tryptophan catabolic process to acetyl-CoA(GO:0019442) |
1.6 | 4.7 | GO:0018900 | dichloromethane metabolic process(GO:0018900) |
1.5 | 7.4 | GO:0051594 | detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594) |
1.1 | 4.3 | GO:1903964 | monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966) |
1.0 | 2.9 | GO:0002014 | vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure(GO:0002014) |
0.9 | 2.7 | GO:2000485 | positive regulation of transcription from RNA polymerase II promoter in response to acidic pH(GO:0061402) regulation of glutamine transport(GO:2000485) |
0.9 | 0.9 | GO:0002589 | regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) |
0.8 | 3.2 | GO:0006556 | S-adenosylmethionine biosynthetic process(GO:0006556) |
0.7 | 3.0 | GO:0032379 | positive regulation of intracellular lipid transport(GO:0032379) positive regulation of intracellular sterol transport(GO:0032382) positive regulation of intracellular cholesterol transport(GO:0032385) lipid hydroperoxide transport(GO:1901373) |
0.7 | 2.9 | GO:0070212 | protein poly-ADP-ribosylation(GO:0070212) |
0.7 | 4.1 | GO:0003383 | apical constriction(GO:0003383) |
0.7 | 2.0 | GO:0006553 | lysine metabolic process(GO:0006553) |
0.6 | 2.5 | GO:1903416 | response to glycoside(GO:1903416) |
0.6 | 1.8 | GO:0035928 | rRNA import into mitochondrion(GO:0035928) |
0.6 | 2.3 | GO:0042270 | protection from natural killer cell mediated cytotoxicity(GO:0042270) |
0.6 | 1.7 | GO:1902524 | positive regulation of protein K48-linked ubiquitination(GO:1902524) |
0.6 | 2.2 | GO:1903237 | negative regulation of leukocyte tethering or rolling(GO:1903237) |
0.5 | 1.6 | GO:0006542 | glutamine biosynthetic process(GO:0006542) |
0.5 | 3.0 | GO:0006083 | acetate metabolic process(GO:0006083) |
0.5 | 2.0 | GO:0051790 | short-chain fatty acid biosynthetic process(GO:0051790) |
0.5 | 1.5 | GO:0039521 | lysosomal microautophagy(GO:0016237) piecemeal microautophagy of nucleus(GO:0034727) suppression by virus of host autophagy(GO:0039521) negative regulation of sphingolipid biosynthesis involved in cellular sphingolipid homeostasis(GO:0090157) |
0.4 | 3.1 | GO:0060266 | negative regulation of respiratory burst involved in inflammatory response(GO:0060266) |
0.4 | 1.3 | GO:0060523 | prostate epithelial cord elongation(GO:0060523) |
0.4 | 1.3 | GO:0043181 | vacuolar sequestering(GO:0043181) |
0.4 | 2.3 | GO:0002317 | plasma cell differentiation(GO:0002317) |
0.4 | 1.5 | GO:1901026 | ripoptosome assembly(GO:0097343) ripoptosome assembly involved in necroptotic process(GO:1901026) |
0.3 | 1.7 | GO:1904721 | regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721) |
0.3 | 1.0 | GO:1905051 | regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053) |
0.3 | 1.0 | GO:1902162 | regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) |
0.3 | 6.1 | GO:0021707 | cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707) |
0.3 | 2.7 | GO:0045345 | MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343) positive regulation of MHC class I biosynthetic process(GO:0045345) |
0.3 | 3.9 | GO:0019885 | antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885) |
0.3 | 3.5 | GO:0005513 | detection of calcium ion(GO:0005513) |
0.3 | 2.5 | GO:0018916 | nitrobenzene metabolic process(GO:0018916) |
0.3 | 0.6 | GO:0060330 | regulation of response to interferon-gamma(GO:0060330) |
0.3 | 2.7 | GO:0006977 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977) |
0.3 | 1.6 | GO:0006499 | N-terminal protein myristoylation(GO:0006499) |
0.3 | 5.3 | GO:0006516 | glycoprotein catabolic process(GO:0006516) |
0.3 | 1.3 | GO:0045716 | positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716) |
0.3 | 2.0 | GO:0060594 | mammary gland specification(GO:0060594) |
0.2 | 0.7 | GO:0000966 | RNA 5'-end processing(GO:0000966) mitochondrial tRNA processing(GO:0090646) |
0.2 | 1.2 | GO:0090290 | positive regulation of osteoclast proliferation(GO:0090290) |
0.2 | 1.9 | GO:0042126 | nitrate metabolic process(GO:0042126) |
0.2 | 1.2 | GO:0045354 | interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354) |
0.2 | 5.1 | GO:0061051 | positive regulation of cell growth involved in cardiac muscle cell development(GO:0061051) |
0.2 | 2.2 | GO:1900038 | negative regulation of cellular response to hypoxia(GO:1900038) |
0.2 | 3.0 | GO:0070842 | aggresome assembly(GO:0070842) |
0.2 | 2.4 | GO:0035457 | cellular response to interferon-alpha(GO:0035457) |
0.2 | 3.0 | GO:0046485 | ether lipid metabolic process(GO:0046485) |
0.2 | 1.7 | GO:0045919 | positive regulation of cytolysis(GO:0045919) |
0.2 | 1.1 | GO:0090370 | negative regulation of cholesterol efflux(GO:0090370) |
0.2 | 0.7 | GO:1903984 | positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984) |
0.2 | 7.8 | GO:0032728 | positive regulation of interferon-beta production(GO:0032728) |
0.2 | 11.8 | GO:0071346 | cellular response to interferon-gamma(GO:0071346) |
0.2 | 0.7 | GO:0070268 | cornification(GO:0070268) |
0.2 | 0.5 | GO:2000616 | negative regulation of histone H3-K9 acetylation(GO:2000616) |
0.2 | 2.2 | GO:0015747 | urate transport(GO:0015747) |
0.2 | 1.7 | GO:2001269 | positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269) |
0.2 | 0.8 | GO:0070366 | regulation of hepatocyte differentiation(GO:0070366) |
0.2 | 0.9 | GO:0051490 | negative regulation of filopodium assembly(GO:0051490) |
0.2 | 2.0 | GO:0048280 | vesicle fusion with Golgi apparatus(GO:0048280) |
0.2 | 1.2 | GO:0006451 | selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451) |
0.1 | 1.2 | GO:0018401 | peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) |
0.1 | 0.4 | GO:0019626 | short-chain fatty acid catabolic process(GO:0019626) |
0.1 | 1.4 | GO:0019243 | methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727) |
0.1 | 2.5 | GO:0046519 | sphingoid metabolic process(GO:0046519) |
0.1 | 0.6 | GO:0010636 | positive regulation of mitochondrial fusion(GO:0010636) |
0.1 | 0.5 | GO:0009992 | cellular water homeostasis(GO:0009992) |
0.1 | 1.2 | GO:1900194 | negative regulation of oocyte development(GO:0060283) negative regulation of oocyte maturation(GO:1900194) |
0.1 | 0.9 | GO:0045065 | cytotoxic T cell differentiation(GO:0045065) |
0.1 | 0.5 | GO:0045726 | positive regulation of integrin biosynthetic process(GO:0045726) |
0.1 | 0.5 | GO:1904430 | negative regulation of t-circle formation(GO:1904430) |
0.1 | 0.4 | GO:0035694 | mitochondrial protein catabolic process(GO:0035694) |
0.1 | 0.4 | GO:2000864 | estradiol secretion(GO:0035938) regulation of estradiol secretion(GO:2000864) |
0.1 | 0.4 | GO:0038095 | Fc-epsilon receptor signaling pathway(GO:0038095) regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625) |
0.1 | 3.3 | GO:0050892 | intestinal absorption(GO:0050892) |
0.1 | 0.1 | GO:1904742 | regulation of telomeric DNA binding(GO:1904742) |
0.1 | 0.3 | GO:0060126 | somatotropin secreting cell differentiation(GO:0060126) |
0.1 | 0.5 | GO:0007341 | penetration of zona pellucida(GO:0007341) |
0.1 | 0.3 | GO:2000836 | epithelial cell proliferation involved in salivary gland morphogenesis(GO:0060664) regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899) positive regulation of androgen secretion(GO:2000836) |
0.1 | 1.1 | GO:0006614 | SRP-dependent cotranslational protein targeting to membrane(GO:0006614) |
0.1 | 1.2 | GO:0007250 | activation of NF-kappaB-inducing kinase activity(GO:0007250) |
0.1 | 0.6 | GO:0043568 | positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568) |
0.1 | 0.4 | GO:0010701 | positive regulation of norepinephrine secretion(GO:0010701) |
0.1 | 2.6 | GO:0035456 | response to interferon-beta(GO:0035456) |
0.1 | 0.3 | GO:0010796 | regulation of multivesicular body size(GO:0010796) |
0.1 | 0.9 | GO:0070932 | histone H3 deacetylation(GO:0070932) |
0.1 | 0.5 | GO:0000492 | box C/D snoRNP assembly(GO:0000492) |
0.1 | 0.3 | GO:0033132 | negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300) |
0.1 | 1.0 | GO:1990403 | embryonic brain development(GO:1990403) |
0.1 | 0.8 | GO:0000712 | resolution of meiotic recombination intermediates(GO:0000712) |
0.1 | 1.4 | GO:0015813 | L-glutamate transport(GO:0015813) |
0.0 | 0.4 | GO:0003373 | dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374) |
0.0 | 1.3 | GO:0010172 | embryonic body morphogenesis(GO:0010172) |
0.0 | 7.1 | GO:0009636 | response to toxic substance(GO:0009636) |
0.0 | 0.3 | GO:0043974 | histone H3-K27 acetylation(GO:0043974) leukemia inhibitory factor signaling pathway(GO:0048861) regulation of histone H3-K27 acetylation(GO:1901674) |
0.0 | 1.4 | GO:0003416 | endochondral bone growth(GO:0003416) |
0.0 | 8.1 | GO:0008654 | phospholipid biosynthetic process(GO:0008654) |
0.0 | 1.2 | GO:0002360 | T cell lineage commitment(GO:0002360) |
0.0 | 0.6 | GO:0016926 | protein desumoylation(GO:0016926) |
0.0 | 0.7 | GO:0006353 | DNA-templated transcription, termination(GO:0006353) |
0.0 | 0.1 | GO:1903972 | regulation of macrophage colony-stimulating factor signaling pathway(GO:1902226) regulation of response to macrophage colony-stimulating factor(GO:1903969) regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903972) |
0.0 | 0.8 | GO:0010818 | T cell chemotaxis(GO:0010818) |
0.0 | 0.9 | GO:2000811 | negative regulation of anoikis(GO:2000811) |
0.0 | 0.4 | GO:0006488 | dolichol-linked oligosaccharide biosynthetic process(GO:0006488) |
0.0 | 0.6 | GO:0070050 | neuron cellular homeostasis(GO:0070050) |
0.0 | 0.7 | GO:0006828 | manganese ion transport(GO:0006828) |
0.0 | 0.4 | GO:0030322 | stabilization of membrane potential(GO:0030322) |
0.0 | 0.4 | GO:0006465 | signal peptide processing(GO:0006465) |
0.0 | 0.8 | GO:0042501 | serine phosphorylation of STAT protein(GO:0042501) |
0.0 | 0.6 | GO:0045116 | protein neddylation(GO:0045116) |
0.0 | 0.4 | GO:0060670 | branching involved in labyrinthine layer morphogenesis(GO:0060670) |
0.0 | 2.0 | GO:0006888 | ER to Golgi vesicle-mediated transport(GO:0006888) |
0.0 | 2.8 | GO:0016052 | carbohydrate catabolic process(GO:0016052) |
0.0 | 1.5 | GO:0046426 | negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893) |
0.0 | 0.3 | GO:0043248 | proteasome assembly(GO:0043248) |
0.0 | 0.1 | GO:0098887 | neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) |
0.0 | 0.1 | GO:1901069 | guanosine-containing compound catabolic process(GO:1901069) |
0.0 | 0.8 | GO:0016239 | positive regulation of macroautophagy(GO:0016239) |
0.0 | 0.3 | GO:0051451 | myoblast migration(GO:0051451) |
0.0 | 0.2 | GO:0042760 | very long-chain fatty acid catabolic process(GO:0042760) |
0.0 | 0.1 | GO:0042697 | menopause(GO:0042697) |
0.0 | 0.3 | GO:0043368 | positive T cell selection(GO:0043368) |
0.0 | 1.0 | GO:0032543 | mitochondrial translation(GO:0032543) |
0.0 | 1.7 | GO:0090090 | negative regulation of canonical Wnt signaling pathway(GO:0090090) |
0.0 | 0.5 | GO:0008631 | intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631) |
0.0 | 2.0 | GO:0048814 | regulation of dendrite morphogenesis(GO:0048814) |
0.0 | 1.5 | GO:0034446 | substrate adhesion-dependent cell spreading(GO:0034446) |
0.0 | 0.1 | GO:0014012 | peripheral nervous system axon regeneration(GO:0014012) |
0.0 | 0.1 | GO:0097500 | receptor localization to nonmotile primary cilium(GO:0097500) |
0.0 | 0.3 | GO:0060325 | face morphogenesis(GO:0060325) |
0.0 | 7.4 | GO:0001501 | skeletal system development(GO:0001501) |
0.0 | 0.9 | GO:2001243 | negative regulation of intrinsic apoptotic signaling pathway(GO:2001243) |
0.0 | 0.7 | GO:0071774 | response to fibroblast growth factor(GO:0071774) |
0.0 | 0.1 | GO:0018026 | peptidyl-lysine monomethylation(GO:0018026) |
0.0 | 0.7 | GO:0046579 | positive regulation of Ras protein signal transduction(GO:0046579) |
0.0 | 0.4 | GO:0019432 | triglyceride biosynthetic process(GO:0019432) |
0.0 | 0.5 | GO:0051965 | positive regulation of synapse assembly(GO:0051965) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 4.1 | GO:0033269 | internode region of axon(GO:0033269) |
0.5 | 7.4 | GO:0045180 | basal cortex(GO:0045180) |
0.4 | 2.2 | GO:1990111 | spermatoproteasome complex(GO:1990111) |
0.3 | 3.9 | GO:0044322 | endoplasmic reticulum quality control compartment(GO:0044322) |
0.3 | 2.5 | GO:0005890 | sodium:potassium-exchanging ATPase complex(GO:0005890) |
0.2 | 9.9 | GO:0035861 | site of double-strand break(GO:0035861) |
0.2 | 3.0 | GO:0031315 | extrinsic component of mitochondrial outer membrane(GO:0031315) |
0.2 | 3.3 | GO:0045179 | apical cortex(GO:0045179) |
0.2 | 1.7 | GO:0042825 | TAP complex(GO:0042825) |
0.2 | 1.3 | GO:0097550 | transcriptional preinitiation complex(GO:0097550) |
0.2 | 3.5 | GO:0031045 | dense core granule(GO:0031045) |
0.2 | 0.5 | GO:0042584 | chromaffin granule membrane(GO:0042584) |
0.2 | 0.8 | GO:0048476 | Holliday junction resolvase complex(GO:0048476) |
0.2 | 1.4 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
0.2 | 2.1 | GO:0097542 | ciliary tip(GO:0097542) |
0.1 | 0.5 | GO:0043564 | Ku70:Ku80 complex(GO:0043564) |
0.1 | 2.0 | GO:0012507 | ER to Golgi transport vesicle membrane(GO:0012507) |
0.1 | 1.3 | GO:0033655 | host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655) |
0.1 | 0.5 | GO:0005726 | perichromatin fibrils(GO:0005726) |
0.1 | 0.9 | GO:1990635 | proximal dendrite(GO:1990635) |
0.1 | 2.1 | GO:0031307 | integral component of mitochondrial outer membrane(GO:0031307) |
0.1 | 1.6 | GO:0097386 | glial cell projection(GO:0097386) |
0.1 | 0.5 | GO:0071438 | invadopodium membrane(GO:0071438) |
0.1 | 0.5 | GO:0098837 | postsynaptic recycling endosome(GO:0098837) |
0.1 | 0.7 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
0.1 | 0.4 | GO:0005787 | signal peptidase complex(GO:0005787) |
0.0 | 1.2 | GO:0031233 | intrinsic component of external side of plasma membrane(GO:0031233) |
0.0 | 1.5 | GO:0000407 | pre-autophagosomal structure(GO:0000407) |
0.0 | 0.9 | GO:0033270 | paranode region of axon(GO:0033270) |
0.0 | 0.7 | GO:0005666 | DNA-directed RNA polymerase III complex(GO:0005666) |
0.0 | 1.8 | GO:0000315 | organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762) |
0.0 | 1.0 | GO:0000314 | organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763) |
0.0 | 2.5 | GO:0005746 | mitochondrial respiratory chain(GO:0005746) |
0.0 | 0.5 | GO:0001673 | male germ cell nucleus(GO:0001673) |
0.0 | 0.4 | GO:0005869 | dynactin complex(GO:0005869) |
0.0 | 0.4 | GO:0030008 | TRAPP complex(GO:0030008) |
0.0 | 0.1 | GO:1990682 | CSF1-CSF1R complex(GO:1990682) |
0.0 | 1.5 | GO:0031941 | filamentous actin(GO:0031941) |
0.0 | 0.7 | GO:0045095 | keratin filament(GO:0045095) |
0.0 | 0.8 | GO:0055038 | recycling endosome membrane(GO:0055038) |
0.0 | 0.6 | GO:0005801 | cis-Golgi network(GO:0005801) |
0.0 | 28.7 | GO:0005615 | extracellular space(GO:0005615) |
0.0 | 3.9 | GO:0042579 | peroxisome(GO:0005777) microbody(GO:0042579) |
0.0 | 0.1 | GO:0005683 | U7 snRNP(GO:0005683) pICln-Sm protein complex(GO:0034715) |
0.0 | 6.5 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
0.0 | 0.7 | GO:0042645 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
0.0 | 0.5 | GO:0030687 | preribosome, large subunit precursor(GO:0030687) |
0.0 | 0.8 | GO:0005793 | endoplasmic reticulum-Golgi intermediate compartment(GO:0005793) |
0.0 | 0.1 | GO:0034464 | BBSome(GO:0034464) |
0.0 | 0.1 | GO:0061700 | GATOR2 complex(GO:0061700) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
6.8 | 20.5 | GO:0004454 | ketohexokinase activity(GO:0004454) |
1.6 | 6.3 | GO:0031735 | CCR10 chemokine receptor binding(GO:0031735) |
1.6 | 4.7 | GO:0047651 | hydrolase activity, acting on acid halide bonds(GO:0016824) hydrolase activity, acting on acid halide bonds, in C-halide compounds(GO:0019120) alkylhalidase activity(GO:0047651) |
1.3 | 5.2 | GO:0016823 | hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823) |
1.3 | 7.8 | GO:0008172 | S-methyltransferase activity(GO:0008172) |
1.1 | 10.0 | GO:0003910 | DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910) |
1.1 | 4.3 | GO:0032896 | palmitoyl-CoA 9-desaturase activity(GO:0032896) |
1.0 | 3.0 | GO:0019807 | aspartoacylase activity(GO:0019807) |
1.0 | 3.0 | GO:0050479 | glyceryl-ether monooxygenase activity(GO:0050479) |
0.9 | 2.7 | GO:0015182 | L-asparagine transmembrane transporter activity(GO:0015182) |
0.9 | 3.5 | GO:0030348 | syntaxin-3 binding(GO:0030348) |
0.7 | 3.0 | GO:0050632 | propanoyl-CoA C-acyltransferase activity(GO:0033814) propionyl-CoA C2-trimethyltridecanoyltransferase activity(GO:0050632) phosphatidylethanolamine transporter activity(GO:1904121) |
0.7 | 7.4 | GO:0004396 | glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) |
0.6 | 1.9 | GO:0008940 | nitrate reductase activity(GO:0008940) |
0.5 | 3.7 | GO:0004556 | alpha-amylase activity(GO:0004556) |
0.5 | 1.6 | GO:0016211 | glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) |
0.5 | 2.0 | GO:0004315 | 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315) |
0.5 | 2.0 | GO:0016647 | oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647) |
0.5 | 1.5 | GO:0019779 | Atg12 activating enzyme activity(GO:0019778) Atg8 activating enzyme activity(GO:0019779) |
0.5 | 3.3 | GO:0005324 | long-chain fatty acid transporter activity(GO:0005324) |
0.4 | 1.3 | GO:0038052 | type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052) |
0.4 | 8.1 | GO:0003841 | 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) |
0.4 | 13.0 | GO:0008009 | chemokine activity(GO:0008009) |
0.3 | 8.4 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
0.3 | 2.2 | GO:0015562 | efflux transmembrane transporter activity(GO:0015562) |
0.3 | 1.3 | GO:0004574 | oligo-1,6-glucosidase activity(GO:0004574) |
0.3 | 0.9 | GO:0004658 | propionyl-CoA carboxylase activity(GO:0004658) |
0.3 | 1.7 | GO:0060698 | endoribonuclease inhibitor activity(GO:0060698) |
0.3 | 2.9 | GO:0001730 | 2'-5'-oligoadenylate synthetase activity(GO:0001730) |
0.3 | 2.3 | GO:0005138 | interleukin-6 receptor binding(GO:0005138) |
0.3 | 2.5 | GO:1990239 | steroid hormone binding(GO:1990239) |
0.2 | 4.8 | GO:0070628 | proteasome binding(GO:0070628) |
0.2 | 1.7 | GO:0046979 | TAP1 binding(GO:0046978) TAP2 binding(GO:0046979) |
0.2 | 1.7 | GO:0001851 | complement component C3b binding(GO:0001851) |
0.2 | 5.1 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
0.2 | 3.9 | GO:1904264 | ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264) |
0.2 | 2.2 | GO:0016813 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813) |
0.2 | 0.8 | GO:0008147 | structural constituent of bone(GO:0008147) |
0.2 | 2.7 | GO:0070513 | death domain binding(GO:0070513) |
0.2 | 1.5 | GO:1990380 | Lys63-specific deubiquitinase activity(GO:0061578) Lys48-specific deubiquitinase activity(GO:1990380) |
0.2 | 2.2 | GO:0005314 | high-affinity glutamate transmembrane transporter activity(GO:0005314) |
0.2 | 5.1 | GO:0005520 | insulin-like growth factor binding(GO:0005520) |
0.2 | 1.4 | GO:0004416 | hydroxyacylglutathione hydrolase activity(GO:0004416) |
0.2 | 1.4 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
0.1 | 1.8 | GO:0008097 | 5S rRNA binding(GO:0008097) |
0.1 | 0.8 | GO:0008195 | phosphatidate phosphatase activity(GO:0008195) |
0.1 | 0.9 | GO:0031730 | CCR5 chemokine receptor binding(GO:0031730) |
0.1 | 1.2 | GO:0031545 | peptidyl-proline 4-dioxygenase activity(GO:0031545) |
0.1 | 0.4 | GO:0034647 | histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647) |
0.1 | 0.3 | GO:0030284 | estrogen receptor activity(GO:0030284) |
0.1 | 0.8 | GO:0008821 | crossover junction endodeoxyribonuclease activity(GO:0008821) |
0.1 | 0.7 | GO:0009019 | tRNA (guanine-N1-)-methyltransferase activity(GO:0009019) |
0.1 | 0.5 | GO:0030171 | voltage-gated proton channel activity(GO:0030171) |
0.1 | 5.6 | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547) |
0.1 | 2.5 | GO:1900750 | glutathione binding(GO:0043295) oligopeptide binding(GO:1900750) |
0.1 | 3.2 | GO:0043531 | ADP binding(GO:0043531) |
0.1 | 0.3 | GO:0005146 | leukemia inhibitory factor receptor binding(GO:0005146) |
0.1 | 0.5 | GO:0061665 | SUMO ligase activity(GO:0061665) |
0.1 | 1.2 | GO:0005123 | death receptor binding(GO:0005123) |
0.1 | 0.7 | GO:0097200 | cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200) |
0.1 | 2.3 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
0.1 | 0.9 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
0.1 | 0.2 | GO:0048019 | receptor antagonist activity(GO:0048019) |
0.1 | 0.7 | GO:0015279 | store-operated calcium channel activity(GO:0015279) |
0.1 | 1.6 | GO:0016676 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
0.0 | 2.1 | GO:0051059 | NF-kappaB binding(GO:0051059) |
0.0 | 2.0 | GO:0071837 | HMG box domain binding(GO:0071837) |
0.0 | 2.3 | GO:0043027 | cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) |
0.0 | 1.4 | GO:0070273 | phosphatidylinositol-4-phosphate binding(GO:0070273) |
0.0 | 1.0 | GO:0005537 | mannose binding(GO:0005537) |
0.0 | 1.1 | GO:0005149 | interleukin-1 receptor binding(GO:0005149) |
0.0 | 0.5 | GO:0051575 | 5'-deoxyribose-5-phosphate lyase activity(GO:0051575) |
0.0 | 0.6 | GO:0008349 | MAP kinase kinase kinase kinase activity(GO:0008349) |
0.0 | 0.6 | GO:0016929 | SUMO-specific protease activity(GO:0016929) |
0.0 | 1.8 | GO:0005044 | scavenger receptor activity(GO:0005044) |
0.0 | 1.9 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
0.0 | 0.7 | GO:0001056 | RNA polymerase III activity(GO:0001056) |
0.0 | 0.8 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
0.0 | 1.8 | GO:0015485 | cholesterol binding(GO:0015485) |
0.0 | 0.9 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
0.0 | 0.4 | GO:0022841 | potassium ion leak channel activity(GO:0022841) |
0.0 | 0.1 | GO:0071209 | histone pre-mRNA DCP binding(GO:0071208) U7 snRNA binding(GO:0071209) |
0.0 | 0.9 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
0.0 | 0.9 | GO:0071889 | 14-3-3 protein binding(GO:0071889) |
0.0 | 0.3 | GO:0016413 | O-acetyltransferase activity(GO:0016413) |
0.0 | 1.6 | GO:0030145 | manganese ion binding(GO:0030145) |
0.0 | 0.4 | GO:0015271 | outward rectifier potassium channel activity(GO:0015271) |
0.0 | 0.1 | GO:0005157 | macrophage colony-stimulating factor receptor binding(GO:0005157) |
0.0 | 0.4 | GO:0046527 | glucosyltransferase activity(GO:0046527) |
0.0 | 3.8 | GO:0008083 | growth factor activity(GO:0008083) |
0.0 | 1.4 | GO:0042974 | retinoic acid receptor binding(GO:0042974) |
0.0 | 1.2 | GO:0001784 | phosphotyrosine binding(GO:0001784) |
0.0 | 0.1 | GO:0010521 | telomerase inhibitor activity(GO:0010521) |
0.0 | 0.7 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
0.0 | 0.4 | GO:0004298 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
0.0 | 2.7 | GO:0004725 | protein tyrosine phosphatase activity(GO:0004725) |
0.0 | 1.2 | GO:0000049 | tRNA binding(GO:0000049) |
0.0 | 4.2 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
0.0 | 0.3 | GO:0031489 | myosin V binding(GO:0031489) |
0.0 | 0.4 | GO:0003995 | acyl-CoA dehydrogenase activity(GO:0003995) |
0.0 | 0.4 | GO:0035259 | glucocorticoid receptor binding(GO:0035259) |
0.0 | 0.2 | GO:0046703 | natural killer cell lectin-like receptor binding(GO:0046703) |
0.0 | 2.5 | GO:0016616 | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0016616) |
0.0 | 1.1 | GO:0019003 | GDP binding(GO:0019003) |
0.0 | 1.8 | GO:0008565 | protein transporter activity(GO:0008565) |
0.0 | 2.3 | GO:0008234 | cysteine-type peptidase activity(GO:0008234) |
0.0 | 0.6 | GO:0030332 | cyclin binding(GO:0030332) |
0.0 | 1.5 | GO:0004860 | protein kinase inhibitor activity(GO:0004860) |
0.0 | 0.3 | GO:0017049 | GTP-Rho binding(GO:0017049) |
0.0 | 0.0 | GO:0004910 | interleukin-1, Type II, blocking receptor activity(GO:0004910) |
0.0 | 1.1 | GO:0002039 | p53 binding(GO:0002039) |
0.0 | 0.2 | GO:0004559 | alpha-mannosidase activity(GO:0004559) mannosidase activity(GO:0015923) |
0.0 | 0.3 | GO:0008198 | ferrous iron binding(GO:0008198) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 8.7 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
0.1 | 8.4 | ST JNK MAPK PATHWAY | JNK MAPK Pathway |
0.1 | 2.3 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
0.1 | 2.7 | PID HIV NEF PATHWAY | HIV-1 Nef: Negative effector of Fas and TNF-alpha |
0.1 | 3.5 | SIG CD40PATHWAYMAP | Genes related to CD40 signaling |
0.1 | 2.1 | PID SYNDECAN 2 PATHWAY | Syndecan-2-mediated signaling events |
0.1 | 2.2 | PID SYNDECAN 4 PATHWAY | Syndecan-4-mediated signaling events |
0.1 | 1.4 | PID NFKAPPAB CANONICAL PATHWAY | Canonical NF-kappaB pathway |
0.1 | 2.0 | PID ARF 3PATHWAY | Arf1 pathway |
0.1 | 4.1 | SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES | Genes related to the insulin receptor pathway |
0.1 | 1.2 | PID PDGFRA PATHWAY | PDGFR-alpha signaling pathway |
0.1 | 7.1 | WNT SIGNALING | Genes related to Wnt-mediated signal transduction |
0.1 | 1.2 | PID HIF1A PATHWAY | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha |
0.0 | 2.0 | PID ATF2 PATHWAY | ATF-2 transcription factor network |
0.0 | 0.3 | ST TYPE I INTERFERON PATHWAY | Type I Interferon (alpha/beta IFN) Pathway |
0.0 | 0.6 | PID ERB GENOMIC PATHWAY | Validated nuclear estrogen receptor beta network |
0.0 | 0.8 | PID IL23 PATHWAY | IL23-mediated signaling events |
0.0 | 1.6 | PID IL4 2PATHWAY | IL4-mediated signaling events |
0.0 | 2.0 | PID RB 1PATHWAY | Regulation of retinoblastoma protein |
0.0 | 1.6 | PID ECADHERIN STABILIZATION PATHWAY | Stabilization and expansion of the E-cadherin adherens junction |
0.0 | 1.1 | PID TCPTP PATHWAY | Signaling events mediated by TCPTP |
0.0 | 0.4 | ST PHOSPHOINOSITIDE 3 KINASE PATHWAY | PI3K Pathway |
0.0 | 1.7 | PID NOTCH PATHWAY | Notch signaling pathway |
0.0 | 1.3 | PID HES HEY PATHWAY | Notch-mediated HES/HEY network |
0.0 | 0.9 | PID P38 ALPHA BETA DOWNSTREAM PATHWAY | Signaling mediated by p38-alpha and p38-beta |
0.0 | 0.9 | PID IL12 2PATHWAY | IL12-mediated signaling events |
0.0 | 5.3 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
0.0 | 0.5 | PID DNA PK PATHWAY | DNA-PK pathway in nonhomologous end joining |
0.0 | 0.3 | PID FRA PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
0.0 | 0.5 | PID RAC1 PATHWAY | RAC1 signaling pathway |
0.0 | 0.4 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 7.5 | REACTOME REGULATION OF COMPLEMENT CASCADE | Genes involved in Regulation of Complement cascade |
0.4 | 7.4 | REACTOME TRYPTOPHAN CATABOLISM | Genes involved in Tryptophan catabolism |
0.3 | 3.5 | REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Acetylcholine Neurotransmitter Release Cycle |
0.2 | 7.2 | REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN | Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein |
0.2 | 9.0 | REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
0.2 | 8.1 | REACTOME SYNTHESIS OF PA | Genes involved in Synthesis of PA |
0.2 | 4.1 | REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION | Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) |
0.1 | 4.1 | REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING | Genes involved in Negative regulators of RIG-I/MDA5 signaling |
0.1 | 3.0 | REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL | Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol |
0.1 | 2.3 | REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC | Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC |
0.1 | 3.2 | REACTOME SULFUR AMINO ACID METABOLISM | Genes involved in Sulfur amino acid metabolism |
0.1 | 1.1 | REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL | Genes involved in NF-kB is activated and signals survival |
0.1 | 1.2 | REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX | Genes involved in TRAF6 mediated induction of TAK1 complex |
0.1 | 1.2 | REACTOME COMMON PATHWAY | Genes involved in Common Pathway |
0.1 | 23.6 | REACTOME METABOLISM OF CARBOHYDRATES | Genes involved in Metabolism of carbohydrates |
0.1 | 4.6 | REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES | Genes involved in Antiviral mechanism by IFN-stimulated genes |
0.1 | 3.9 | REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
0.1 | 1.3 | REACTOME TRAF6 MEDIATED IRF7 ACTIVATION | Genes involved in TRAF6 mediated IRF7 activation |
0.1 | 0.7 | REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS | Genes involved in Elevation of cytosolic Ca2+ levels |
0.1 | 1.3 | REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION | Genes involved in Mitochondrial Fatty Acid Beta-Oxidation |
0.1 | 1.2 | REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA | Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha |
0.1 | 1.6 | REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION | Genes involved in Amino acid synthesis and interconversion (transamination) |
0.1 | 1.2 | REACTOME IL 7 SIGNALING | Genes involved in Interleukin-7 signaling |
0.1 | 2.0 | REACTOME ENOS ACTIVATION AND REGULATION | Genes involved in eNOS activation and regulation |
0.1 | 2.5 | REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
0.1 | 1.5 | REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
0.1 | 2.7 | REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
0.0 | 2.5 | REACTOME ION TRANSPORT BY P TYPE ATPASES | Genes involved in Ion transport by P-type ATPases |
0.0 | 1.7 | REACTOME GLUTATHIONE CONJUGATION | Genes involved in Glutathione conjugation |
0.0 | 0.8 | REACTOME SYNTHESIS OF PE | Genes involved in Synthesis of PE |
0.0 | 2.1 | REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G | Genes involved in Vif-mediated degradation of APOBEC3G |
0.0 | 2.6 | REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | Genes involved in NOTCH1 Intracellular Domain Regulates Transcription |
0.0 | 0.7 | REACTOME ACTIVATION OF GENES BY ATF4 | Genes involved in Activation of Genes by ATF4 |
0.0 | 1.3 | REACTOME NUCLEAR SIGNALING BY ERBB4 | Genes involved in Nuclear signaling by ERBB4 |
0.0 | 0.7 | REACTOME RNA POL III CHAIN ELONGATION | Genes involved in RNA Polymerase III Chain Elongation |
0.0 | 0.4 | REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS | Genes involved in Tandem pore domain potassium channels |
0.0 | 0.3 | REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS | Genes involved in Regulation of Water Balance by Renal Aquaporins |
0.0 | 0.5 | REACTOME INTEGRATION OF PROVIRUS | Genes involved in Integration of provirus |
0.0 | 0.4 | REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN | Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin |
0.0 | 0.3 | REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION | Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion |
0.0 | 0.6 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
0.0 | 0.4 | REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN | Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein |
0.0 | 0.9 | REACTOME RESPIRATORY ELECTRON TRANSPORT | Genes involved in Respiratory electron transport |