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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Sox8

Z-value: 0.41

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Transcription factors associated with Sox8

Gene Symbol Gene ID Gene Info
ENSMUSG00000024176.4 SRY (sex determining region Y)-box 8

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Sox8mm10_v2_chr17_-_25570678_255706940.153.8e-01Click!

Activity profile of Sox8 motif

Sorted Z-values of Sox8 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Sox8

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0002149 hypochlorous acid metabolic process(GO:0002148) hypochlorous acid biosynthetic process(GO:0002149)
0.1 0.4 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.1 0.5 GO:0031296 positive regulation of germinal center formation(GO:0002636) B cell costimulation(GO:0031296)
0.1 0.7 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.1 1.1 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.2 GO:0050917 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.0 0.1 GO:2000820 negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)
0.0 0.2 GO:0001927 exocyst assembly(GO:0001927)
0.0 0.4 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.0 0.1 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.0 0.1 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055) negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.0 0.1 GO:0060467 negative regulation of fertilization(GO:0060467)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.1 1.1 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.4 GO:0005861 troponin complex(GO:0005861)
0.0 0.1 GO:0071942 XPC complex(GO:0071942)
0.0 0.2 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.3 GO:0010369 chromocenter(GO:0010369)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 0.4 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.0 0.1 GO:0035939 microsatellite binding(GO:0035939)
0.0 0.2 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 1.8 GO:0004601 peroxidase activity(GO:0004601)
0.0 0.1 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.1 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.0 0.5 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.1 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.5 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.8 PID IL23 PATHWAY IL23-mediated signaling events
0.0 1.1 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 REACTOME GLYCOLYSIS Genes involved in Glycolysis