avrg: GSE58827: Dynamics of the Mouse Liver
Gene Symbol | Gene ID | Gene Info |
---|---|---|
Egr3
|
ENSMUSG00000033730.3 | early growth response 3 |
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Egr3 | mm10_v2_chr14_+_70077375_70077445 | -0.10 | 5.7e-01 | Click! |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
3.2 | 9.7 | GO:0019442 | tryptophan catabolic process to acetyl-CoA(GO:0019442) |
1.2 | 3.5 | GO:0045014 | carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014) |
0.6 | 2.9 | GO:0070859 | positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253) |
0.5 | 2.1 | GO:0048807 | female genitalia morphogenesis(GO:0048807) |
0.5 | 4.3 | GO:0060613 | fat pad development(GO:0060613) |
0.5 | 1.4 | GO:0060010 | Sertoli cell fate commitment(GO:0060010) |
0.5 | 1.4 | GO:1903334 | positive regulation of protein folding(GO:1903334) |
0.4 | 2.5 | GO:0034197 | acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197) |
0.4 | 1.1 | GO:0071603 | dibenzo-p-dioxin metabolic process(GO:0018894) endothelial cell-cell adhesion(GO:0071603) |
0.4 | 1.4 | GO:0070368 | positive regulation of hepatocyte differentiation(GO:0070368) |
0.4 | 1.4 | GO:0003360 | brainstem development(GO:0003360) |
0.3 | 1.3 | GO:0006030 | chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032) |
0.3 | 1.1 | GO:0000379 | tRNA-type intron splice site recognition and cleavage(GO:0000379) |
0.3 | 0.8 | GO:0061763 | multivesicular body-lysosome fusion(GO:0061763) |
0.3 | 0.8 | GO:0021852 | pyramidal neuron migration(GO:0021852) |
0.3 | 1.6 | GO:1900170 | negative regulation of glucocorticoid mediated signaling pathway(GO:1900170) |
0.3 | 1.3 | GO:0021564 | vagus nerve development(GO:0021564) |
0.2 | 2.2 | GO:0051045 | negative regulation of membrane protein ectodomain proteolysis(GO:0051045) |
0.2 | 1.0 | GO:0060023 | soft palate development(GO:0060023) |
0.2 | 0.5 | GO:2000812 | response to rapamycin(GO:1901355) regulation of barbed-end actin filament capping(GO:2000812) |
0.2 | 1.5 | GO:0060164 | regulation of timing of neuron differentiation(GO:0060164) |
0.2 | 1.4 | GO:0035021 | negative regulation of Rac protein signal transduction(GO:0035021) |
0.2 | 1.1 | GO:0000320 | re-entry into mitotic cell cycle(GO:0000320) |
0.1 | 1.9 | GO:0070166 | enamel mineralization(GO:0070166) |
0.1 | 0.9 | GO:1990416 | cellular response to brain-derived neurotrophic factor stimulus(GO:1990416) |
0.1 | 0.5 | GO:0045054 | constitutive secretory pathway(GO:0045054) |
0.1 | 1.7 | GO:0097201 | negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201) |
0.1 | 2.2 | GO:0043046 | regulation of gene expression by genetic imprinting(GO:0006349) DNA methylation involved in gamete generation(GO:0043046) |
0.1 | 0.6 | GO:0019388 | galactose catabolic process(GO:0019388) |
0.1 | 0.5 | GO:0006621 | protein retention in ER lumen(GO:0006621) |
0.1 | 0.5 | GO:2000672 | negative regulation of motor neuron apoptotic process(GO:2000672) |
0.1 | 2.0 | GO:0010763 | positive regulation of fibroblast migration(GO:0010763) |
0.1 | 0.3 | GO:2000325 | regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327) |
0.1 | 0.6 | GO:1902510 | regulation of apoptotic DNA fragmentation(GO:1902510) |
0.1 | 1.6 | GO:0001516 | prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457) |
0.1 | 2.2 | GO:0072348 | sulfur compound transport(GO:0072348) |
0.0 | 2.9 | GO:0046580 | negative regulation of Ras protein signal transduction(GO:0046580) |
0.0 | 0.4 | GO:0061303 | cornea development in camera-type eye(GO:0061303) |
0.0 | 0.5 | GO:0048280 | vesicle fusion with Golgi apparatus(GO:0048280) |
0.0 | 0.2 | GO:0097527 | necroptotic signaling pathway(GO:0097527) |
0.0 | 0.8 | GO:0006474 | N-terminal protein amino acid acetylation(GO:0006474) |
0.0 | 1.2 | GO:0070979 | protein K11-linked ubiquitination(GO:0070979) |
0.0 | 0.3 | GO:0019800 | peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800) |
0.0 | 0.2 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
0.0 | 1.3 | GO:0010718 | positive regulation of epithelial to mesenchymal transition(GO:0010718) |
0.0 | 0.5 | GO:0043486 | histone exchange(GO:0043486) |
0.0 | 0.6 | GO:0071364 | cellular response to epidermal growth factor stimulus(GO:0071364) |
0.0 | 1.4 | GO:0060999 | positive regulation of dendritic spine development(GO:0060999) |
0.0 | 0.5 | GO:0001829 | trophectodermal cell differentiation(GO:0001829) |
0.0 | 0.5 | GO:0035640 | exploration behavior(GO:0035640) |
0.0 | 1.3 | GO:0007200 | phospholipase C-activating G-protein coupled receptor signaling pathway(GO:0007200) |
0.0 | 0.7 | GO:0050873 | brown fat cell differentiation(GO:0050873) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 1.4 | GO:0097059 | CNTFR-CLCF1 complex(GO:0097059) |
0.3 | 0.8 | GO:0031417 | NatC complex(GO:0031417) |
0.2 | 0.9 | GO:0071953 | elastic fiber(GO:0071953) |
0.2 | 1.1 | GO:0000214 | tRNA-intron endonuclease complex(GO:0000214) |
0.2 | 1.4 | GO:0042825 | TAP complex(GO:0042825) |
0.1 | 2.1 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
0.1 | 0.6 | GO:0090498 | extrinsic component of Golgi membrane(GO:0090498) |
0.1 | 2.5 | GO:0031528 | microvillus membrane(GO:0031528) |
0.1 | 0.5 | GO:0036195 | muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195) |
0.1 | 0.9 | GO:0031209 | SCAR complex(GO:0031209) |
0.1 | 1.4 | GO:0032156 | septin cytoskeleton(GO:0032156) |
0.1 | 0.5 | GO:0030015 | CCR4-NOT core complex(GO:0030015) |
0.0 | 1.3 | GO:0005614 | interstitial matrix(GO:0005614) |
0.0 | 0.7 | GO:0005605 | basal lamina(GO:0005605) |
0.0 | 0.5 | GO:0012507 | ER to Golgi transport vesicle membrane(GO:0012507) |
0.0 | 0.3 | GO:0000506 | glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506) |
0.0 | 1.1 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
0.0 | 1.7 | GO:0032587 | ruffle membrane(GO:0032587) |
0.0 | 0.8 | GO:0032154 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
0.0 | 0.2 | GO:0072546 | ER membrane protein complex(GO:0072546) |
0.0 | 0.5 | GO:0055038 | recycling endosome membrane(GO:0055038) |
0.0 | 1.2 | GO:0005581 | collagen trimer(GO:0005581) |
0.0 | 0.4 | GO:0005763 | organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763) |
0.0 | 0.4 | GO:0001533 | cornified envelope(GO:0001533) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.4 | 9.7 | GO:0004833 | tryptophan 2,3-dioxygenase activity(GO:0004833) |
0.7 | 2.2 | GO:0030977 | taurine binding(GO:0030977) |
0.5 | 1.4 | GO:0019153 | protein-disulfide reductase (glutathione) activity(GO:0019153) |
0.4 | 1.6 | GO:0050220 | prostaglandin-E synthase activity(GO:0050220) |
0.3 | 1.3 | GO:0004568 | chitinase activity(GO:0004568) |
0.3 | 1.6 | GO:0004883 | glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051) |
0.2 | 2.2 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
0.2 | 1.4 | GO:0004897 | ciliary neurotrophic factor receptor activity(GO:0004897) |
0.2 | 1.1 | GO:0000213 | tRNA-intron endonuclease activity(GO:0000213) |
0.1 | 2.1 | GO:0016918 | retinal binding(GO:0016918) retinol binding(GO:0019841) |
0.1 | 0.6 | GO:0016649 | electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649) |
0.1 | 0.5 | GO:0046923 | ER retention sequence binding(GO:0046923) |
0.1 | 2.9 | GO:0001222 | transcription corepressor binding(GO:0001222) |
0.1 | 1.4 | GO:0035014 | phosphatidylinositol 3-kinase regulator activity(GO:0035014) |
0.1 | 2.0 | GO:0004708 | MAP kinase kinase activity(GO:0004708) |
0.1 | 2.5 | GO:0034185 | apolipoprotein binding(GO:0034185) |
0.1 | 0.6 | GO:0004614 | phosphoglucomutase activity(GO:0004614) |
0.1 | 1.4 | GO:0004707 | MAP kinase activity(GO:0004707) |
0.1 | 3.5 | GO:0001205 | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205) |
0.1 | 0.5 | GO:0004652 | polynucleotide adenylyltransferase activity(GO:0004652) |
0.1 | 1.9 | GO:0043539 | protein serine/threonine kinase activator activity(GO:0043539) |
0.0 | 0.8 | GO:0004596 | peptide alpha-N-acetyltransferase activity(GO:0004596) |
0.0 | 1.1 | GO:0070064 | proline-rich region binding(GO:0070064) |
0.0 | 2.7 | GO:0001784 | phosphotyrosine binding(GO:0001784) |
0.0 | 2.5 | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547) |
0.0 | 1.1 | GO:0070330 | aromatase activity(GO:0070330) |
0.0 | 1.3 | GO:0008188 | neuropeptide receptor activity(GO:0008188) |
0.0 | 1.0 | GO:0042056 | chemoattractant activity(GO:0042056) |
0.0 | 0.3 | GO:0017176 | phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176) |
0.0 | 0.7 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
0.0 | 0.6 | GO:0003746 | translation elongation factor activity(GO:0003746) |
0.0 | 1.2 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
0.0 | 1.7 | GO:0008146 | sulfotransferase activity(GO:0008146) |
0.0 | 0.3 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
0.0 | 0.5 | GO:0031489 | myosin V binding(GO:0031489) |
0.0 | 0.9 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
0.0 | 4.1 | GO:0016874 | ligase activity(GO:0016874) |
0.0 | 0.5 | GO:0005242 | inward rectifier potassium channel activity(GO:0005242) |
0.0 | 5.4 | GO:0001227 | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227) |
0.0 | 0.3 | GO:0032183 | SUMO binding(GO:0032183) |
0.0 | 0.9 | GO:0048365 | Rac GTPase binding(GO:0048365) |
0.0 | 0.6 | GO:0043425 | bHLH transcription factor binding(GO:0043425) |
0.0 | 0.5 | GO:0005484 | SNAP receptor activity(GO:0005484) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 2.9 | PID CIRCADIAN PATHWAY | Circadian rhythm pathway |
0.1 | 6.5 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
0.1 | 1.1 | SA REG CASCADE OF CYCLIN EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
0.1 | 2.9 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
0.1 | 2.5 | PID ARF6 PATHWAY | Arf6 signaling events |
0.0 | 1.2 | PID NFKAPPAB CANONICAL PATHWAY | Canonical NF-kappaB pathway |
0.0 | 1.4 | PID RETINOIC ACID PATHWAY | Retinoic acid receptors-mediated signaling |
0.0 | 1.6 | PID IFNG PATHWAY | IFN-gamma pathway |
0.0 | 0.7 | PID FOXM1 PATHWAY | FOXM1 transcription factor network |
0.0 | 0.7 | PID MAPK TRK PATHWAY | Trk receptor signaling mediated by the MAPK pathway |
0.0 | 0.4 | PID SYNDECAN 2 PATHWAY | Syndecan-2-mediated signaling events |
0.0 | 0.8 | PID ERBB1 INTERNALIZATION PATHWAY | Internalization of ErbB1 |
0.0 | 0.6 | PID CERAMIDE PATHWAY | Ceramide signaling pathway |
0.0 | 0.8 | PID SMAD2 3NUCLEAR PATHWAY | Regulation of nuclear SMAD2/3 signaling |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 9.7 | REACTOME TRYPTOPHAN CATABOLISM | Genes involved in Tryptophan catabolism |
0.4 | 3.2 | REACTOME CREATION OF C4 AND C2 ACTIVATORS | Genes involved in Creation of C4 and C2 activators |
0.1 | 4.9 | REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS | Genes involved in Regulation of gene expression in beta cells |
0.1 | 1.4 | REACTOME CALNEXIN CALRETICULIN CYCLE | Genes involved in Calnexin/calreticulin cycle |
0.1 | 2.2 | REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS | Genes involved in Na+/Cl- dependent neurotransmitter transporters |
0.1 | 2.5 | REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
0.1 | 2.9 | REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA | Genes involved in Circadian Repression of Expression by REV-ERBA |
0.1 | 1.1 | REACTOME ENDOGENOUS STEROLS | Genes involved in Endogenous sterols |
0.1 | 1.2 | REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA | Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha |
0.0 | 3.0 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
0.0 | 1.1 | REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION | Genes involved in Pre-NOTCH Transcription and Translation |
0.0 | 0.6 | REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS | Genes involved in Glycogen breakdown (glycogenolysis) |
0.0 | 0.8 | REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT | Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT) |
0.0 | 3.9 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
0.0 | 0.3 | REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI | Genes involved in Synthesis of glycosylphosphatidylinositol (GPI) |