avrg: GSE58827: Dynamics of the Mouse Liver
Gene Symbol | Gene ID | Gene Info |
---|---|---|
Insm1
|
ENSMUSG00000068154.4 | insulinoma-associated 1 |
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Insm1 | mm10_v2_chr2_+_146221921_146221921 | 0.41 | 1.4e-02 | Click! |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.5 | 12.4 | GO:0000738 | DNA catabolic process, exonucleolytic(GO:0000738) |
1.6 | 4.9 | GO:0090481 | pyrimidine nucleotide-sugar transmembrane transport(GO:0090481) |
1.2 | 4.8 | GO:0098795 | mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795) |
0.9 | 2.7 | GO:1901254 | regulation of translation at synapse, modulating synaptic transmission(GO:0099547) regulation of translation at postsynapse, modulating synaptic transmission(GO:0099578) positive regulation of intracellular transport of viral material(GO:1901254) |
0.8 | 2.3 | GO:0014878 | response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878) |
0.7 | 3.0 | GO:0046898 | response to cycloheximide(GO:0046898) |
0.7 | 2.0 | GO:0060488 | orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490) |
0.7 | 5.2 | GO:0030174 | regulation of DNA-dependent DNA replication initiation(GO:0030174) |
0.6 | 1.9 | GO:0090076 | positive regulation of endoplasmic reticulum calcium ion concentration(GO:0032470) maintenance of mitochondrion location(GO:0051659) relaxation of skeletal muscle(GO:0090076) |
0.6 | 2.9 | GO:0045347 | negative regulation of MHC class II biosynthetic process(GO:0045347) |
0.6 | 2.2 | GO:0006659 | phosphatidylserine biosynthetic process(GO:0006659) |
0.5 | 7.5 | GO:0060087 | relaxation of vascular smooth muscle(GO:0060087) |
0.5 | 1.9 | GO:0045659 | negative regulation of neutrophil differentiation(GO:0045659) |
0.4 | 1.2 | GO:2001034 | positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034) |
0.4 | 1.5 | GO:0035712 | T-helper 2 cell activation(GO:0035712) regulation of T-helper 2 cell activation(GO:2000569) positive regulation of T-helper 2 cell activation(GO:2000570) |
0.3 | 1.0 | GO:0001546 | preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162) |
0.3 | 2.4 | GO:0034454 | microtubule anchoring at centrosome(GO:0034454) |
0.3 | 1.2 | GO:0030860 | regulation of polarized epithelial cell differentiation(GO:0030860) |
0.3 | 2.7 | GO:0030916 | otic vesicle formation(GO:0030916) |
0.3 | 1.3 | GO:0021993 | initiation of neural tube closure(GO:0021993) |
0.3 | 3.0 | GO:0045631 | regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980) |
0.2 | 4.3 | GO:0006968 | cellular defense response(GO:0006968) |
0.2 | 1.7 | GO:1901300 | positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300) |
0.2 | 0.9 | GO:1904049 | negative regulation of spontaneous neurotransmitter secretion(GO:1904049) |
0.2 | 0.4 | GO:0060853 | arterial endothelial cell fate commitment(GO:0060844) blood vessel endothelial cell fate commitment(GO:0060846) Notch signaling pathway involved in arterial endothelial cell fate commitment(GO:0060853) regulation of cell adhesion involved in heart morphogenesis(GO:0061344) blood vessel endothelial cell fate specification(GO:0097101) positive regulation of ephrin receptor signaling pathway(GO:1901189) |
0.2 | 3.3 | GO:0021670 | lateral ventricle development(GO:0021670) |
0.2 | 0.9 | GO:0061511 | centriole elongation(GO:0061511) |
0.2 | 0.7 | GO:0046368 | GDP-L-fucose metabolic process(GO:0046368) |
0.2 | 1.9 | GO:0005513 | detection of calcium ion(GO:0005513) |
0.2 | 2.6 | GO:2000096 | positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096) |
0.2 | 0.6 | GO:0030576 | Cajal body organization(GO:0030576) |
0.1 | 1.3 | GO:0070072 | vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072) |
0.1 | 0.7 | GO:0044027 | hypermethylation of CpG island(GO:0044027) |
0.1 | 2.5 | GO:0060736 | prostate gland growth(GO:0060736) |
0.1 | 3.1 | GO:0072520 | seminiferous tubule development(GO:0072520) |
0.1 | 0.3 | GO:0009106 | lipoate metabolic process(GO:0009106) |
0.1 | 2.6 | GO:0043486 | histone exchange(GO:0043486) |
0.1 | 0.4 | GO:2001025 | positive regulation of response to drug(GO:2001025) |
0.1 | 0.5 | GO:0072718 | response to cisplatin(GO:0072718) |
0.1 | 0.8 | GO:0060907 | positive regulation of macrophage cytokine production(GO:0060907) |
0.1 | 1.1 | GO:0030150 | protein import into mitochondrial matrix(GO:0030150) |
0.1 | 0.8 | GO:2001256 | regulation of store-operated calcium entry(GO:2001256) |
0.0 | 1.1 | GO:0046855 | inositol phosphate dephosphorylation(GO:0046855) |
0.0 | 1.8 | GO:0033006 | regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304) |
0.0 | 0.3 | GO:0072104 | glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104) |
0.0 | 1.3 | GO:0044342 | type B pancreatic cell proliferation(GO:0044342) |
0.0 | 0.3 | GO:1903026 | negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026) |
0.0 | 0.2 | GO:2000705 | regulation of dense core granule biogenesis(GO:2000705) |
0.0 | 3.2 | GO:1902017 | regulation of cilium assembly(GO:1902017) |
0.0 | 1.1 | GO:0033622 | integrin activation(GO:0033622) |
0.0 | 0.9 | GO:0016578 | histone deubiquitination(GO:0016578) |
0.0 | 0.3 | GO:0019227 | neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870) |
0.0 | 0.4 | GO:0019985 | translesion synthesis(GO:0019985) |
0.0 | 0.3 | GO:0043353 | enucleate erythrocyte differentiation(GO:0043353) |
0.0 | 3.2 | GO:0006334 | nucleosome assembly(GO:0006334) |
0.0 | 1.1 | GO:0031572 | G2 DNA damage checkpoint(GO:0031572) |
0.0 | 3.5 | GO:0014065 | phosphatidylinositol 3-kinase signaling(GO:0014065) |
0.0 | 0.1 | GO:0061343 | cell adhesion involved in heart morphogenesis(GO:0061343) |
0.0 | 0.4 | GO:0043374 | CD8-positive, alpha-beta T cell differentiation(GO:0043374) |
0.0 | 0.7 | GO:0000387 | spliceosomal snRNP assembly(GO:0000387) |
0.0 | 0.1 | GO:0000160 | phosphorelay signal transduction system(GO:0000160) |
0.0 | 0.4 | GO:0048266 | behavioral response to pain(GO:0048266) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.7 | 2.7 | GO:1902737 | viral replication complex(GO:0019034) dendritic filopodium(GO:1902737) |
0.5 | 2.0 | GO:0060187 | cell pole(GO:0060187) |
0.5 | 2.4 | GO:0036449 | microtubule minus-end(GO:0036449) |
0.4 | 3.1 | GO:0005828 | kinetochore microtubule(GO:0005828) |
0.3 | 1.9 | GO:0031673 | H zone(GO:0031673) |
0.3 | 4.3 | GO:0097539 | ciliary transition fiber(GO:0097539) |
0.3 | 13.1 | GO:0015030 | Cajal body(GO:0015030) |
0.3 | 3.0 | GO:0097136 | Bcl-2 family protein complex(GO:0097136) |
0.2 | 0.9 | GO:1990761 | growth cone lamellipodium(GO:1990761) |
0.2 | 0.7 | GO:0005683 | U7 snRNP(GO:0005683) |
0.2 | 1.3 | GO:0000220 | vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220) |
0.1 | 1.2 | GO:0001940 | male pronucleus(GO:0001940) |
0.1 | 1.2 | GO:0044214 | spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717) |
0.1 | 1.1 | GO:0005742 | mitochondrial outer membrane translocase complex(GO:0005742) |
0.1 | 5.8 | GO:0001772 | immunological synapse(GO:0001772) |
0.1 | 0.8 | GO:0030314 | junctional membrane complex(GO:0030314) |
0.1 | 0.4 | GO:0002193 | MAML1-RBP-Jkappa- ICN1 complex(GO:0002193) |
0.1 | 6.7 | GO:0016529 | sarcoplasmic reticulum(GO:0016529) |
0.1 | 1.0 | GO:0005686 | U2 snRNP(GO:0005686) |
0.1 | 2.6 | GO:0008023 | transcription elongation factor complex(GO:0008023) |
0.0 | 0.7 | GO:0032580 | Golgi cisterna membrane(GO:0032580) |
0.0 | 3.2 | GO:0000786 | nucleosome(GO:0000786) |
0.0 | 3.1 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
0.0 | 0.1 | GO:0031428 | box C/D snoRNP complex(GO:0031428) |
0.0 | 3.6 | GO:0000932 | cytoplasmic mRNA processing body(GO:0000932) |
0.0 | 0.9 | GO:0034451 | centriolar satellite(GO:0034451) |
0.0 | 0.7 | GO:0001741 | XY body(GO:0001741) |
0.0 | 0.4 | GO:0005839 | proteasome core complex(GO:0005839) |
0.0 | 3.3 | GO:0001650 | fibrillar center(GO:0001650) |
0.0 | 2.4 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
0.0 | 0.3 | GO:0042571 | immunoglobulin complex, circulating(GO:0042571) |
0.0 | 1.3 | GO:0031519 | PcG protein complex(GO:0031519) |
0.0 | 4.8 | GO:0005769 | early endosome(GO:0005769) |
0.0 | 0.4 | GO:0044665 | MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339) |
0.0 | 1.7 | GO:0030863 | cortical cytoskeleton(GO:0030863) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
3.1 | 12.4 | GO:0008859 | exoribonuclease II activity(GO:0008859) |
0.6 | 6.7 | GO:0005338 | nucleotide-sugar transmembrane transporter activity(GO:0005338) |
0.4 | 2.7 | GO:0033592 | RNA strand annealing activity(GO:0033592) |
0.4 | 1.8 | GO:0010853 | cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250) |
0.3 | 1.6 | GO:0030620 | U2 snRNA binding(GO:0030620) |
0.3 | 1.9 | GO:0051425 | PTB domain binding(GO:0051425) |
0.3 | 3.0 | GO:0051434 | BH3 domain binding(GO:0051434) |
0.3 | 2.2 | GO:0017169 | CDP-alcohol phosphatidyltransferase activity(GO:0017169) |
0.3 | 1.1 | GO:0016316 | phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) |
0.2 | 2.9 | GO:0051525 | NFAT protein binding(GO:0051525) |
0.2 | 0.6 | GO:0070122 | isopeptidase activity(GO:0070122) ubiquitin-like protein-specific isopeptidase activity(GO:0070138) SUMO-specific isopeptidase activity(GO:0070140) |
0.2 | 3.1 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
0.2 | 1.1 | GO:0015288 | porin activity(GO:0015288) |
0.1 | 2.3 | GO:0031432 | titin binding(GO:0031432) |
0.1 | 0.4 | GO:0045322 | unmethylated CpG binding(GO:0045322) |
0.1 | 0.7 | GO:0003886 | DNA (cytosine-5-)-methyltransferase activity(GO:0003886) |
0.1 | 3.0 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
0.1 | 3.8 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
0.1 | 1.9 | GO:0015269 | calcium-activated potassium channel activity(GO:0015269) |
0.1 | 1.3 | GO:0008553 | hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553) |
0.1 | 1.3 | GO:0051864 | histone demethylase activity (H3-K36 specific)(GO:0051864) |
0.1 | 1.1 | GO:0050321 | tau-protein kinase activity(GO:0050321) |
0.1 | 0.7 | GO:0008417 | fucosyltransferase activity(GO:0008417) |
0.1 | 1.5 | GO:0004697 | protein kinase C activity(GO:0004697) |
0.0 | 1.1 | GO:0032794 | GTPase activating protein binding(GO:0032794) |
0.0 | 0.5 | GO:0032454 | histone demethylase activity (H3-K9 specific)(GO:0032454) |
0.0 | 4.0 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
0.0 | 0.3 | GO:0043023 | ribosomal large subunit binding(GO:0043023) |
0.0 | 0.1 | GO:0034511 | U3 snoRNA binding(GO:0034511) |
0.0 | 1.8 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
0.0 | 1.0 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
0.0 | 1.7 | GO:0001221 | transcription cofactor binding(GO:0001221) |
0.0 | 1.0 | GO:0043175 | RNA polymerase core enzyme binding(GO:0043175) |
0.0 | 0.8 | GO:0004864 | protein phosphatase inhibitor activity(GO:0004864) |
0.0 | 4.8 | GO:0004386 | helicase activity(GO:0004386) |
0.0 | 0.4 | GO:0070530 | K63-linked polyubiquitin binding(GO:0070530) |
0.0 | 0.3 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
0.0 | 0.4 | GO:0004298 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
0.0 | 0.3 | GO:0034987 | immunoglobulin receptor binding(GO:0034987) |
0.0 | 0.1 | GO:0000155 | phosphorelay sensor kinase activity(GO:0000155) |
0.0 | 2.8 | GO:0042393 | histone binding(GO:0042393) |
0.0 | 0.5 | GO:0043236 | laminin binding(GO:0043236) |
0.0 | 0.4 | GO:0001103 | RNA polymerase II repressing transcription factor binding(GO:0001103) |
0.0 | 0.2 | GO:0015271 | outward rectifier potassium channel activity(GO:0015271) |
0.0 | 1.2 | GO:0008013 | beta-catenin binding(GO:0008013) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 4.3 | PID TCR JNK PATHWAY | JNK signaling in the CD4+ TCR pathway |
0.1 | 3.0 | SA PROGRAMMED CELL DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
0.1 | 1.0 | PID ALK2 PATHWAY | ALK2 signaling events |
0.1 | 4.3 | PID PLK1 PATHWAY | PLK1 signaling events |
0.1 | 5.2 | PID MYC REPRESS PATHWAY | Validated targets of C-MYC transcriptional repression |
0.0 | 1.0 | ST INTERLEUKIN 4 PATHWAY | Interleukin 4 (IL-4) Pathway |
0.0 | 1.3 | ST WNT BETA CATENIN PATHWAY | Wnt/beta-catenin Pathway |
0.0 | 1.5 | PID CD8 TCR PATHWAY | TCR signaling in naïve CD8+ T cells |
0.0 | 2.3 | PID CMYB PATHWAY | C-MYB transcription factor network |
0.0 | 1.1 | NABA COLLAGENS | Genes encoding collagen proteins |
0.0 | 1.1 | PID LKB1 PATHWAY | LKB1 signaling events |
0.0 | 0.8 | PID ILK PATHWAY | Integrin-linked kinase signaling |
0.0 | 0.4 | PID PS1 PATHWAY | Presenilin action in Notch and Wnt signaling |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 9.4 | REACTOME CGMP EFFECTS | Genes involved in cGMP effects |
0.3 | 4.1 | REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION | Genes involved in Apoptosis induced DNA fragmentation |
0.2 | 12.4 | REACTOME INTERFERON ALPHA BETA SIGNALING | Genes involved in Interferon alpha/beta signaling |
0.2 | 5.5 | REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION | Genes involved in Pre-NOTCH Transcription and Translation |
0.1 | 3.0 | REACTOME INFLAMMASOMES | Genes involved in Inflammasomes |
0.1 | 4.3 | REACTOME GENERATION OF SECOND MESSENGER MOLECULES | Genes involved in Generation of second messenger molecules |
0.1 | 2.7 | REACTOME FGFR1 LIGAND BINDING AND ACTIVATION | Genes involved in FGFR1 ligand binding and activation |
0.1 | 3.1 | REACTOME KINESINS | Genes involved in Kinesins |
0.1 | 1.9 | REACTOME PLATELET CALCIUM HOMEOSTASIS | Genes involved in Platelet calcium homeostasis |
0.1 | 1.7 | REACTOME SIGNALING BY NODAL | Genes involved in Signaling by NODAL |
0.1 | 1.1 | REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE | Genes involved in Synthesis of PIPs at the early endosome membrane |
0.1 | 0.7 | REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS | Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs |
0.0 | 1.3 | REACTOME INSULIN RECEPTOR RECYCLING | Genes involved in Insulin receptor recycling |
0.0 | 1.3 | REACTOME DOWNSTREAM TCR SIGNALING | Genes involved in Downstream TCR signaling |
0.0 | 0.7 | REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI | Genes involved in N-glycan antennae elongation in the medial/trans-Golgi |
0.0 | 1.1 | REACTOME MITOCHONDRIAL PROTEIN IMPORT | Genes involved in Mitochondrial Protein Import |
0.0 | 2.2 | REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS | Genes involved in Glycerophospholipid biosynthesis |
0.0 | 1.1 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |