avrg: GSE58827: Dynamics of the Mouse Liver
Gene Symbol | Gene ID | Gene Info |
---|---|---|
Glis3
|
ENSMUSG00000052942.7 | GLIS family zinc finger 3 |
Glis3
|
ENSMUSG00000091294.1 | GLIS family zinc finger 3 |
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Glis3 | mm10_v2_chr19_-_28680077_28680122 | -0.32 | 5.6e-02 | Click! |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.8 | 5.6 | GO:0070494 | regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495) |
0.4 | 1.3 | GO:1905072 | detection of oxygen(GO:0003032) cardiac jelly development(GO:1905072) |
0.4 | 6.5 | GO:0048387 | negative regulation of retinoic acid receptor signaling pathway(GO:0048387) |
0.3 | 0.9 | GO:0006208 | pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859) |
0.3 | 0.8 | GO:0071651 | positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651) |
0.3 | 1.3 | GO:0021914 | negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914) |
0.2 | 1.2 | GO:0032915 | positive regulation of transforming growth factor beta2 production(GO:0032915) |
0.2 | 0.7 | GO:0060010 | Sertoli cell fate commitment(GO:0060010) |
0.2 | 0.6 | GO:0003127 | detection of nodal flow(GO:0003127) detection of endogenous stimulus(GO:0009726) cellular response to water stimulus(GO:0071462) |
0.2 | 0.6 | GO:2001160 | regulation of histone H3-K79 methylation(GO:2001160) |
0.2 | 0.8 | GO:0003360 | brainstem development(GO:0003360) |
0.2 | 1.3 | GO:0070814 | hydrogen sulfide biosynthetic process(GO:0070814) |
0.2 | 0.7 | GO:0051305 | chromosome movement towards spindle pole(GO:0051305) |
0.2 | 1.0 | GO:0032349 | positive regulation of aldosterone metabolic process(GO:0032346) positive regulation of aldosterone biosynthetic process(GO:0032349) |
0.2 | 0.8 | GO:0035426 | extracellular matrix-cell signaling(GO:0035426) |
0.2 | 1.4 | GO:0070345 | negative regulation of fat cell proliferation(GO:0070345) |
0.1 | 1.2 | GO:0060613 | fat pad development(GO:0060613) |
0.1 | 0.9 | GO:1903691 | positive regulation of wound healing, spreading of epidermal cells(GO:1903691) |
0.1 | 1.2 | GO:0007196 | adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196) |
0.1 | 1.9 | GO:0048672 | positive regulation of collateral sprouting(GO:0048672) |
0.1 | 0.1 | GO:0070342 | brown fat cell proliferation(GO:0070342) regulation of brown fat cell proliferation(GO:0070347) |
0.1 | 0.6 | GO:0003376 | sphingosine-1-phosphate signaling pathway(GO:0003376) eye pigmentation(GO:0048069) |
0.1 | 0.3 | GO:0035574 | histone H4-K20 demethylation(GO:0035574) |
0.1 | 1.0 | GO:0034626 | fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) |
0.1 | 0.5 | GO:0072675 | osteoclast fusion(GO:0072675) |
0.1 | 0.5 | GO:0007296 | vitellogenesis(GO:0007296) |
0.1 | 0.1 | GO:0043366 | beta selection(GO:0043366) |
0.1 | 0.5 | GO:0042078 | germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) positive regulation of NK T cell differentiation(GO:0051138) germline stem cell asymmetric division(GO:0098728) |
0.1 | 0.3 | GO:0097374 | sensory neuron axon guidance(GO:0097374) |
0.1 | 1.9 | GO:0010971 | positive regulation of G2/M transition of mitotic cell cycle(GO:0010971) |
0.1 | 0.6 | GO:0043587 | tongue morphogenesis(GO:0043587) |
0.1 | 0.8 | GO:0035810 | positive regulation of urine volume(GO:0035810) |
0.1 | 1.3 | GO:0071577 | zinc II ion transmembrane transport(GO:0071577) |
0.1 | 0.7 | GO:2000507 | positive regulation of energy homeostasis(GO:2000507) |
0.1 | 0.4 | GO:0060903 | positive regulation of meiosis I(GO:0060903) |
0.1 | 1.3 | GO:0055098 | response to low-density lipoprotein particle(GO:0055098) |
0.1 | 0.2 | GO:0021622 | oculomotor nerve morphogenesis(GO:0021622) oculomotor nerve formation(GO:0021623) |
0.1 | 1.4 | GO:0021692 | cerebellar Purkinje cell layer morphogenesis(GO:0021692) |
0.0 | 0.6 | GO:1900113 | negative regulation of histone H3-K9 trimethylation(GO:1900113) |
0.0 | 0.6 | GO:0070914 | UV-damage excision repair(GO:0070914) |
0.0 | 1.7 | GO:0046856 | phosphatidylinositol dephosphorylation(GO:0046856) |
0.0 | 0.5 | GO:0055093 | response to hyperoxia(GO:0055093) cellular response to hyperoxia(GO:0071455) |
0.0 | 0.2 | GO:0032227 | negative regulation of synaptic transmission, dopaminergic(GO:0032227) |
0.0 | 0.9 | GO:0016578 | histone deubiquitination(GO:0016578) |
0.0 | 0.6 | GO:0021521 | ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573) |
0.0 | 0.2 | GO:0060214 | endocardium formation(GO:0060214) |
0.0 | 0.2 | GO:0014053 | negative regulation of gamma-aminobutyric acid secretion(GO:0014053) |
0.0 | 0.5 | GO:0043984 | histone H4-K16 acetylation(GO:0043984) |
0.0 | 0.5 | GO:0070816 | phosphorylation of RNA polymerase II C-terminal domain(GO:0070816) |
0.0 | 0.8 | GO:0043153 | entrainment of circadian clock by photoperiod(GO:0043153) |
0.0 | 0.3 | GO:2000766 | negative regulation of cytoplasmic translation(GO:2000766) |
0.0 | 0.1 | GO:0035470 | positive regulation of vascular wound healing(GO:0035470) |
0.0 | 0.5 | GO:0018195 | peptidyl-arginine modification(GO:0018195) |
0.0 | 0.5 | GO:0014067 | negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067) |
0.0 | 0.3 | GO:0032780 | negative regulation of ATPase activity(GO:0032780) |
0.0 | 1.6 | GO:0042147 | retrograde transport, endosome to Golgi(GO:0042147) |
0.0 | 0.4 | GO:1990126 | retrograde transport, endosome to plasma membrane(GO:1990126) |
0.0 | 0.8 | GO:0046677 | response to antibiotic(GO:0046677) |
0.0 | 0.4 | GO:0045671 | negative regulation of osteoclast differentiation(GO:0045671) |
0.0 | 0.2 | GO:0090394 | negative regulation of excitatory postsynaptic potential(GO:0090394) |
0.0 | 0.8 | GO:0071385 | cellular response to glucocorticoid stimulus(GO:0071385) |
0.0 | 0.1 | GO:0044828 | negative regulation by host of viral genome replication(GO:0044828) |
0.0 | 0.1 | GO:0086073 | bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073) |
0.0 | 0.5 | GO:0031648 | protein destabilization(GO:0031648) |
0.0 | 0.1 | GO:1902775 | mitochondrial large ribosomal subunit assembly(GO:1902775) |
0.0 | 0.0 | GO:0002268 | follicular dendritic cell activation(GO:0002266) follicular dendritic cell differentiation(GO:0002268) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 2.1 | GO:0008091 | spectrin(GO:0008091) |
0.2 | 8.3 | GO:0080008 | Cul4-RING E3 ubiquitin ligase complex(GO:0080008) |
0.2 | 0.8 | GO:0097059 | CNTFR-CLCF1 complex(GO:0097059) |
0.1 | 0.6 | GO:0098553 | integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553) |
0.1 | 0.5 | GO:0072487 | MSL complex(GO:0072487) |
0.1 | 0.7 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
0.1 | 5.6 | GO:0009925 | basal plasma membrane(GO:0009925) |
0.1 | 0.4 | GO:0071203 | WASH complex(GO:0071203) |
0.1 | 0.2 | GO:0031084 | BLOC-2 complex(GO:0031084) |
0.1 | 0.5 | GO:0000439 | core TFIIH complex(GO:0000439) |
0.1 | 0.9 | GO:0000124 | SAGA complex(GO:0000124) |
0.0 | 0.6 | GO:0016589 | NURF complex(GO:0016589) |
0.0 | 0.2 | GO:0038039 | G-protein coupled receptor heterodimeric complex(GO:0038039) |
0.0 | 0.6 | GO:0031618 | nuclear pericentric heterochromatin(GO:0031618) |
0.0 | 0.5 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
0.0 | 0.7 | GO:0071782 | endoplasmic reticulum tubular network(GO:0071782) |
0.0 | 1.2 | GO:0035861 | site of double-strand break(GO:0035861) |
0.0 | 0.1 | GO:0044194 | cytolytic granule(GO:0044194) |
0.0 | 1.6 | GO:0045335 | phagocytic vesicle(GO:0045335) |
0.0 | 3.9 | GO:0090575 | RNA polymerase II transcription factor complex(GO:0090575) |
0.0 | 1.2 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
0.0 | 0.1 | GO:0033503 | HULC complex(GO:0033503) |
0.0 | 0.9 | GO:0032154 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
0.0 | 0.8 | GO:0005747 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
0.0 | 0.4 | GO:0034364 | high-density lipoprotein particle(GO:0034364) |
0.0 | 0.0 | GO:0033257 | Bcl3/NF-kappaB2 complex(GO:0033257) |
0.0 | 0.8 | GO:0031903 | peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.4 | 5.6 | GO:0005008 | hepatocyte growth factor-activated receptor activity(GO:0005008) |
0.8 | 5.9 | GO:0052650 | NADP-retinol dehydrogenase activity(GO:0052650) |
0.2 | 1.3 | GO:0046912 | transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912) |
0.2 | 1.7 | GO:0052629 | phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629) |
0.2 | 1.3 | GO:0005534 | galactose binding(GO:0005534) |
0.2 | 1.2 | GO:0001642 | group III metabotropic glutamate receptor activity(GO:0001642) |
0.2 | 0.6 | GO:0048763 | calcium-induced calcium release activity(GO:0048763) |
0.2 | 0.6 | GO:0046624 | sphingolipid transporter activity(GO:0046624) |
0.2 | 1.3 | GO:0045545 | syndecan binding(GO:0045545) |
0.1 | 0.9 | GO:0016812 | nucleobase binding(GO:0002054) hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812) |
0.1 | 1.2 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
0.1 | 0.8 | GO:0004897 | ciliary neurotrophic factor receptor activity(GO:0004897) |
0.1 | 0.8 | GO:0043426 | MRF binding(GO:0043426) |
0.1 | 0.8 | GO:0043237 | laminin-1 binding(GO:0043237) |
0.1 | 0.3 | GO:0035575 | histone demethylase activity (H4-K20 specific)(GO:0035575) |
0.1 | 1.0 | GO:0070700 | BMP receptor binding(GO:0070700) |
0.1 | 1.0 | GO:0102338 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
0.1 | 0.7 | GO:0008494 | translation activator activity(GO:0008494) |
0.1 | 0.8 | GO:0050700 | CARD domain binding(GO:0050700) |
0.1 | 0.7 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) |
0.1 | 0.7 | GO:0035014 | phosphatidylinositol 3-kinase regulator activity(GO:0035014) |
0.0 | 0.5 | GO:0004576 | oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
0.0 | 0.5 | GO:0001206 | transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206) |
0.0 | 1.3 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
0.0 | 0.2 | GO:0004965 | G-protein coupled GABA receptor activity(GO:0004965) |
0.0 | 1.3 | GO:0071837 | HMG box domain binding(GO:0071837) |
0.0 | 0.1 | GO:0043183 | vascular endothelial growth factor receptor 1 binding(GO:0043183) |
0.0 | 0.5 | GO:0032454 | histone demethylase activity (H3-K9 specific)(GO:0032454) |
0.0 | 0.3 | GO:1990715 | mRNA CDS binding(GO:1990715) |
0.0 | 0.8 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
0.0 | 1.8 | GO:0019003 | GDP binding(GO:0019003) |
0.0 | 0.6 | GO:0070410 | co-SMAD binding(GO:0070410) |
0.0 | 0.5 | GO:0008353 | RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353) |
0.0 | 0.7 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
0.0 | 0.3 | GO:0005522 | profilin binding(GO:0005522) |
0.0 | 0.8 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
0.0 | 0.3 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
0.0 | 0.5 | GO:0001223 | transcription coactivator binding(GO:0001223) |
0.0 | 0.1 | GO:0086080 | protein binding involved in heterotypic cell-cell adhesion(GO:0086080) |
0.0 | 0.9 | GO:0030374 | ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374) |
0.0 | 1.2 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
0.0 | 0.6 | GO:0003684 | damaged DNA binding(GO:0003684) |
0.0 | 1.8 | GO:0047485 | protein N-terminus binding(GO:0047485) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 5.2 | PID ARF6 PATHWAY | Arf6 signaling events |
0.1 | 7.2 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
0.0 | 0.8 | PID ERBB NETWORK PATHWAY | ErbB receptor signaling network |
0.0 | 2.3 | PID BMP PATHWAY | BMP receptor signaling |
0.0 | 2.0 | NABA BASEMENT MEMBRANES | Genes encoding structural components of basement membranes |
0.0 | 1.3 | PID ALK1 PATHWAY | ALK1 signaling events |
0.0 | 0.7 | PID SMAD2 3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
0.0 | 0.7 | PID CIRCADIAN PATHWAY | Circadian rhythm pathway |
0.0 | 1.2 | SA B CELL RECEPTOR COMPLEXES | Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases. |
0.0 | 2.1 | PID E2F PATHWAY | E2F transcription factor network |
0.0 | 1.3 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
0.0 | 0.5 | PID HDAC CLASSIII PATHWAY | Signaling events mediated by HDAC Class III |
0.0 | 0.7 | PID RETINOIC ACID PATHWAY | Retinoic acid receptors-mediated signaling |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 2.1 | REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX | Genes involved in CDC6 association with the ORC:origin complex |
0.1 | 5.8 | REACTOME SEMA4D IN SEMAPHORIN SIGNALING | Genes involved in Sema4D in semaphorin signaling |
0.1 | 1.5 | REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |
0.1 | 1.2 | REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS | Genes involved in Activation of the AP-1 family of transcription factors |
0.1 | 1.3 | REACTOME ZINC TRANSPORTERS | Genes involved in Zinc transporters |
0.1 | 0.9 | REACTOME PYRIMIDINE CATABOLISM | Genes involved in Pyrimidine catabolism |
0.1 | 1.3 | REACTOME CHOLESTEROL BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
0.1 | 0.8 | REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 | Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 |
0.1 | 1.4 | REACTOME DEADENYLATION OF MRNA | Genes involved in Deadenylation of mRNA |
0.0 | 1.9 | REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION | Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription |
0.0 | 0.7 | REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION | Genes involved in Apoptosis induced DNA fragmentation |
0.0 | 1.0 | REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS | Genes involved in Synthesis of very long-chain fatty acyl-CoAs |
0.0 | 0.8 | REACTOME SHC1 EVENTS IN ERBB4 SIGNALING | Genes involved in SHC1 events in ERBB4 signaling |
0.0 | 2.1 | REACTOME NCAM SIGNALING FOR NEURITE OUT GROWTH | Genes involved in NCAM signaling for neurite out-growth |
0.0 | 0.5 | REACTOME FORMATION OF INCISION COMPLEX IN GG NER | Genes involved in Formation of incision complex in GG-NER |
0.0 | 0.8 | REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION | Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression |
0.0 | 0.8 | REACTOME NETRIN1 SIGNALING | Genes involved in Netrin-1 signaling |
0.0 | 0.5 | REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS | Genes involved in Regulation of gene expression in beta cells |
0.0 | 0.6 | REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE | Genes involved in Synthesis of PIPs at the plasma membrane |