avrg: GSE58827: Dynamics of the Mouse Liver
Gene Symbol | Gene ID | Gene Info |
---|---|---|
Ptf1a
|
ENSMUSG00000026735.2 | pancreas specific transcription factor, 1a |
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Ptf1a | mm10_v2_chr2_+_19445632_19445663 | 0.78 | 2.7e-08 | Click! |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.4 | 7.3 | GO:0061402 | positive regulation of transcription from RNA polymerase II promoter in response to acidic pH(GO:0061402) |
1.0 | 3.0 | GO:1902283 | negative regulation of primary amine oxidase activity(GO:1902283) |
0.7 | 109.6 | GO:0007586 | digestion(GO:0007586) |
0.6 | 1.9 | GO:0008588 | release of cytoplasmic sequestered NF-kappaB(GO:0008588) |
0.5 | 1.4 | GO:2000412 | lymphocyte migration into lymphoid organs(GO:0097021) positive regulation of thymocyte migration(GO:2000412) regulation of dendritic cell dendrite assembly(GO:2000547) |
0.5 | 1.4 | GO:0071460 | cellular response to cell-matrix adhesion(GO:0071460) |
0.4 | 0.8 | GO:0010980 | regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980) |
0.4 | 1.5 | GO:0006069 | ethanol oxidation(GO:0006069) |
0.3 | 1.0 | GO:0042222 | interleukin-1 biosynthetic process(GO:0042222) |
0.3 | 1.2 | GO:0034760 | negative regulation of iron ion transport(GO:0034757) negative regulation of iron ion transmembrane transport(GO:0034760) |
0.3 | 0.5 | GO:0035461 | vitamin transmembrane transport(GO:0035461) |
0.2 | 0.7 | GO:1990166 | protein localization to site of double-strand break(GO:1990166) |
0.2 | 0.9 | GO:0015886 | heme transport(GO:0015886) |
0.1 | 1.1 | GO:0006004 | fucose metabolic process(GO:0006004) |
0.1 | 0.5 | GO:0060857 | establishment of glial blood-brain barrier(GO:0060857) |
0.1 | 0.5 | GO:0060447 | peripheral nervous system axon regeneration(GO:0014012) bud outgrowth involved in lung branching(GO:0060447) |
0.1 | 0.8 | GO:0019254 | carnitine metabolic process, CoA-linked(GO:0019254) |
0.1 | 15.0 | GO:0031638 | zymogen activation(GO:0031638) |
0.1 | 0.8 | GO:0071569 | protein ufmylation(GO:0071569) |
0.1 | 0.3 | GO:0034224 | cellular response to zinc ion starvation(GO:0034224) |
0.1 | 0.4 | GO:0072675 | osteoclast fusion(GO:0072675) |
0.1 | 0.2 | GO:1904457 | positive regulation of neuronal action potential(GO:1904457) |
0.1 | 0.6 | GO:0051725 | protein de-ADP-ribosylation(GO:0051725) |
0.1 | 0.2 | GO:0046271 | coumarin metabolic process(GO:0009804) phenylpropanoid catabolic process(GO:0046271) |
0.1 | 0.3 | GO:0001550 | ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) |
0.1 | 0.4 | GO:1905049 | negative regulation of metallopeptidase activity(GO:1905049) |
0.1 | 1.4 | GO:0071378 | growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378) |
0.1 | 1.0 | GO:0032825 | positive regulation of natural killer cell differentiation(GO:0032825) |
0.1 | 0.2 | GO:0006481 | C-terminal protein methylation(GO:0006481) |
0.0 | 0.2 | GO:0006049 | UDP-N-acetylglucosamine catabolic process(GO:0006049) |
0.0 | 1.0 | GO:2000353 | positive regulation of endothelial cell apoptotic process(GO:2000353) |
0.0 | 18.2 | GO:0006887 | exocytosis(GO:0006887) |
0.0 | 3.4 | GO:0038083 | peptidyl-tyrosine autophosphorylation(GO:0038083) |
0.0 | 6.4 | GO:0002377 | immunoglobulin production(GO:0002377) |
0.0 | 0.2 | GO:0009814 | defense response, incompatible interaction(GO:0009814) defense response to bacterium, incompatible interaction(GO:0009816) regulation of defense response to bacterium, incompatible interaction(GO:1902477) |
0.0 | 0.4 | GO:0033227 | dsRNA transport(GO:0033227) |
0.0 | 1.0 | GO:0071711 | basement membrane organization(GO:0071711) |
0.0 | 0.4 | GO:0007196 | adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196) |
0.0 | 0.3 | GO:2000857 | positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860) |
0.0 | 0.3 | GO:0035356 | cellular triglyceride homeostasis(GO:0035356) |
0.0 | 0.8 | GO:0000413 | protein peptidyl-prolyl isomerization(GO:0000413) |
0.0 | 0.3 | GO:2000580 | positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582) |
0.0 | 0.3 | GO:1904262 | negative regulation of TORC1 signaling(GO:1904262) |
0.0 | 0.2 | GO:0072540 | T-helper 17 cell lineage commitment(GO:0072540) |
0.0 | 0.2 | GO:0015868 | purine ribonucleotide transport(GO:0015868) |
0.0 | 0.8 | GO:0006182 | cGMP biosynthetic process(GO:0006182) |
0.0 | 0.2 | GO:0060174 | limb bud formation(GO:0060174) |
0.0 | 0.8 | GO:0051496 | positive regulation of stress fiber assembly(GO:0051496) |
0.0 | 1.2 | GO:0048663 | neuron fate commitment(GO:0048663) |
0.0 | 0.6 | GO:0045646 | regulation of erythrocyte differentiation(GO:0045646) |
0.0 | 0.1 | GO:0019372 | lipoxygenase pathway(GO:0019372) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.0 | 15.5 | GO:0042589 | zymogen granule membrane(GO:0042589) |
0.2 | 18.8 | GO:0030667 | secretory granule membrane(GO:0030667) |
0.1 | 16.8 | GO:0072562 | blood microparticle(GO:0072562) |
0.1 | 101.5 | GO:0005615 | extracellular space(GO:0005615) |
0.0 | 0.2 | GO:0044316 | cone cell pedicle(GO:0044316) |
0.0 | 0.4 | GO:0048787 | presynaptic active zone membrane(GO:0048787) |
0.0 | 0.8 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
0.0 | 0.1 | GO:0097381 | photoreceptor disc membrane(GO:0097381) |
0.0 | 0.3 | GO:0061700 | GATOR2 complex(GO:0061700) |
0.0 | 0.1 | GO:0031428 | box C/D snoRNP complex(GO:0031428) |
0.0 | 0.3 | GO:0045180 | basal cortex(GO:0045180) |
0.0 | 0.7 | GO:0035861 | site of double-strand break(GO:0035861) |
0.0 | 0.4 | GO:0000145 | exocyst(GO:0000145) |
0.0 | 2.6 | GO:0031234 | extrinsic component of cytoplasmic side of plasma membrane(GO:0031234) |
0.0 | 1.4 | GO:0031526 | brush border membrane(GO:0031526) |
0.0 | 0.8 | GO:0000786 | nucleosome(GO:0000786) |
0.0 | 0.2 | GO:0005686 | U2 snRNP(GO:0005686) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.7 | 2.1 | GO:0052595 | tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596) |
0.5 | 112.0 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
0.5 | 1.5 | GO:0004024 | alcohol dehydrogenase activity, zinc-dependent(GO:0004024) |
0.3 | 2.1 | GO:0005499 | vitamin D binding(GO:0005499) |
0.3 | 1.1 | GO:0042806 | fucose binding(GO:0042806) |
0.3 | 1.4 | GO:0008269 | JAK pathway signal transduction adaptor activity(GO:0008269) |
0.2 | 5.4 | GO:0004550 | nucleoside diphosphate kinase activity(GO:0004550) |
0.2 | 0.9 | GO:0015232 | heme transporter activity(GO:0015232) |
0.2 | 0.8 | GO:0004092 | carnitine O-acetyltransferase activity(GO:0004092) |
0.1 | 1.4 | GO:0019957 | C-C chemokine binding(GO:0019957) |
0.1 | 0.3 | GO:0050252 | retinol O-fatty-acyltransferase activity(GO:0050252) |
0.1 | 0.7 | GO:0003910 | DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910) |
0.1 | 0.8 | GO:0001730 | 2'-5'-oligoadenylate synthetase activity(GO:0001730) |
0.1 | 0.2 | GO:0004063 | aryldialkylphosphatase activity(GO:0004063) |
0.1 | 0.4 | GO:0051033 | nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033) |
0.1 | 0.4 | GO:0001642 | group III metabotropic glutamate receptor activity(GO:0001642) |
0.1 | 0.5 | GO:0045545 | syndecan binding(GO:0045545) |
0.1 | 0.2 | GO:0003880 | protein C-terminal carboxyl O-methyltransferase activity(GO:0003880) |
0.0 | 3.4 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
0.0 | 0.2 | GO:0003827 | alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827) |
0.0 | 0.5 | GO:0090482 | vitamin transmembrane transporter activity(GO:0090482) |
0.0 | 0.8 | GO:0017166 | vinculin binding(GO:0017166) |
0.0 | 0.8 | GO:0005527 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
0.0 | 0.8 | GO:0097371 | MDM2/MDM4 family protein binding(GO:0097371) |
0.0 | 0.8 | GO:0004383 | guanylate cyclase activity(GO:0004383) |
0.0 | 0.6 | GO:0031418 | L-ascorbic acid binding(GO:0031418) |
0.0 | 0.3 | GO:0005025 | transforming growth factor beta receptor activity, type I(GO:0005025) |
0.0 | 0.4 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
0.0 | 0.7 | GO:0004435 | phosphatidylinositol phospholipase C activity(GO:0004435) |
0.0 | 0.2 | GO:0042289 | MHC class II protein binding(GO:0042289) |
0.0 | 0.1 | GO:0004052 | arachidonate 12-lipoxygenase activity(GO:0004052) |
0.0 | 0.8 | GO:0016709 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709) |
0.0 | 0.3 | GO:0031432 | titin binding(GO:0031432) |
0.0 | 0.1 | GO:0034511 | U3 snoRNA binding(GO:0034511) |
0.0 | 2.9 | GO:0052689 | carboxylic ester hydrolase activity(GO:0052689) |
0.0 | 1.2 | GO:0005507 | copper ion binding(GO:0005507) |
0.0 | 0.2 | GO:0005243 | gap junction channel activity(GO:0005243) |
0.0 | 0.5 | GO:0051879 | Hsp90 protein binding(GO:0051879) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 7.3 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
0.1 | 23.9 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
0.1 | 3.4 | PID GLYPICAN 1PATHWAY | Glypican 1 network |
0.0 | 1.7 | PID INTEGRIN1 PATHWAY | Beta1 integrin cell surface interactions |
0.0 | 1.4 | PID IL2 1PATHWAY | IL2-mediated signaling events |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.9 | 26.1 | REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX | Genes involved in Degradation of the extracellular matrix |
0.6 | 7.3 | REACTOME ABACAVIR TRANSPORT AND METABOLISM | Genes involved in Abacavir transport and metabolism |
0.1 | 3.4 | REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS | Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers |
0.0 | 0.5 | REACTOME VITAMIN B5 PANTOTHENATE METABOLISM | Genes involved in Vitamin B5 (pantothenate) metabolism |
0.0 | 1.4 | REACTOME GROWTH HORMONE RECEPTOR SIGNALING | Genes involved in Growth hormone receptor signaling |
0.0 | 1.4 | REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
0.0 | 0.8 | REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE | Genes involved in Cytochrome P450 - arranged by substrate type |
0.0 | 0.8 | REACTOME PEROXISOMAL LIPID METABOLISM | Genes involved in Peroxisomal lipid metabolism |
0.0 | 0.8 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
0.0 | 0.4 | REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |
0.0 | 0.9 | REACTOME METABOLISM OF VITAMINS AND COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
0.0 | 0.3 | REACTOME RETROGRADE NEUROTROPHIN SIGNALLING | Genes involved in Retrograde neurotrophin signalling |
0.0 | 0.3 | REACTOME ZINC TRANSPORTERS | Genes involved in Zinc transporters |
0.0 | 0.3 | REACTOME SIGNALING BY BMP | Genes involved in Signaling by BMP |