avrg: GSE58827: Dynamics of the Mouse Liver
Gene Symbol | Gene ID | Gene Info |
---|---|---|
Nr2f6
|
ENSMUSG00000002393.8 | nuclear receptor subfamily 2, group F, member 6 |
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Nr2f6 | mm10_v2_chr8_-_71381907_71381977 | -0.63 | 4.4e-05 | Click! |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.5 | 4.5 | GO:0036088 | D-serine catabolic process(GO:0036088) D-alanine family amino acid metabolic process(GO:0046144) D-alanine metabolic process(GO:0046436) D-alanine catabolic process(GO:0055130) |
1.1 | 18.3 | GO:0030277 | maintenance of gastrointestinal epithelium(GO:0030277) |
0.8 | 3.4 | GO:2000402 | negative regulation of lymphocyte migration(GO:2000402) |
0.8 | 3.8 | GO:2000660 | negative regulation of interleukin-1-mediated signaling pathway(GO:2000660) |
0.8 | 2.3 | GO:0006597 | spermine biosynthetic process(GO:0006597) |
0.7 | 3.6 | GO:1902167 | positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902167) |
0.7 | 2.9 | GO:1902896 | terminal web assembly(GO:1902896) |
0.6 | 2.9 | GO:0035616 | histone H2B conserved C-terminal lysine deubiquitination(GO:0035616) |
0.5 | 2.3 | GO:0045347 | negative regulation of MHC class II biosynthetic process(GO:0045347) |
0.5 | 4.6 | GO:0048170 | positive regulation of long-term neuronal synaptic plasticity(GO:0048170) |
0.4 | 2.2 | GO:0030321 | transepithelial chloride transport(GO:0030321) |
0.4 | 1.7 | GO:1904306 | regulation of voltage-gated chloride channel activity(GO:1902941) positive regulation of voltage-gated chloride channel activity(GO:1902943) positive regulation of gastro-intestinal system smooth muscle contraction(GO:1904306) |
0.4 | 4.3 | GO:0070940 | dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940) |
0.4 | 2.5 | GO:0097428 | protein maturation by iron-sulfur cluster transfer(GO:0097428) |
0.4 | 1.4 | GO:0046075 | dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) dTTP metabolic process(GO:0046075) |
0.3 | 1.7 | GO:0071105 | response to interleukin-11(GO:0071105) |
0.3 | 2.0 | GO:0035609 | C-terminal protein deglutamylation(GO:0035609) |
0.3 | 1.2 | GO:0006014 | D-ribose metabolic process(GO:0006014) |
0.3 | 1.7 | GO:0002457 | T cell antigen processing and presentation(GO:0002457) |
0.3 | 3.5 | GO:0046007 | negative regulation of activated T cell proliferation(GO:0046007) |
0.2 | 6.4 | GO:0035634 | response to stilbenoid(GO:0035634) |
0.2 | 4.2 | GO:0014883 | transition between fast and slow fiber(GO:0014883) |
0.2 | 4.8 | GO:0032211 | negative regulation of telomere maintenance via telomerase(GO:0032211) |
0.2 | 0.5 | GO:0021691 | cerebellar Purkinje cell layer maturation(GO:0021691) |
0.1 | 0.9 | GO:0071985 | multivesicular body sorting pathway(GO:0071985) |
0.1 | 0.6 | GO:0035521 | monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522) |
0.1 | 1.2 | GO:0010757 | regulation of blood vessel size by renin-angiotensin(GO:0002034) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072) negative regulation of plasminogen activation(GO:0010757) |
0.1 | 3.5 | GO:0006991 | response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501) |
0.1 | 1.4 | GO:0048563 | post-embryonic organ morphogenesis(GO:0048563) |
0.1 | 0.1 | GO:0034443 | negative regulation of lipoprotein oxidation(GO:0034443) |
0.1 | 2.1 | GO:0046543 | development of secondary female sexual characteristics(GO:0046543) |
0.1 | 8.4 | GO:0006611 | protein export from nucleus(GO:0006611) |
0.1 | 2.4 | GO:0000289 | nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289) |
0.1 | 1.4 | GO:0048096 | chromatin-mediated maintenance of transcription(GO:0048096) |
0.1 | 5.4 | GO:0051865 | protein autoubiquitination(GO:0051865) |
0.1 | 2.7 | GO:0000387 | spliceosomal snRNP assembly(GO:0000387) |
0.1 | 3.6 | GO:0045737 | positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) |
0.1 | 1.5 | GO:0007095 | mitotic G2 DNA damage checkpoint(GO:0007095) |
0.1 | 1.8 | GO:0048268 | clathrin coat assembly(GO:0048268) |
0.1 | 3.4 | GO:1901998 | toxin transport(GO:1901998) |
0.1 | 1.1 | GO:0045899 | positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899) |
0.1 | 2.9 | GO:0006414 | translational elongation(GO:0006414) |
0.1 | 4.5 | GO:0050829 | defense response to Gram-negative bacterium(GO:0050829) |
0.1 | 0.9 | GO:0001778 | plasma membrane repair(GO:0001778) |
0.1 | 2.6 | GO:0008156 | negative regulation of DNA replication(GO:0008156) |
0.0 | 0.6 | GO:0032780 | negative regulation of ATPase activity(GO:0032780) |
0.0 | 0.3 | GO:0002159 | desmosome assembly(GO:0002159) |
0.0 | 0.2 | GO:0032290 | peripheral nervous system myelin formation(GO:0032290) regulation of enamel mineralization(GO:0070173) |
0.0 | 0.3 | GO:0070601 | centromeric sister chromatid cohesion(GO:0070601) |
0.0 | 3.2 | GO:0002088 | lens development in camera-type eye(GO:0002088) |
0.0 | 5.4 | GO:0014065 | phosphatidylinositol 3-kinase signaling(GO:0014065) |
0.0 | 0.6 | GO:0043968 | histone H2A acetylation(GO:0043968) |
0.0 | 0.1 | GO:0010726 | positive regulation of hydrogen peroxide metabolic process(GO:0010726) |
0.0 | 1.3 | GO:0043001 | Golgi to plasma membrane protein transport(GO:0043001) |
0.0 | 0.2 | GO:0043928 | nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928) |
0.0 | 0.0 | GO:1901668 | regulation of superoxide dismutase activity(GO:1901668) |
0.0 | 0.6 | GO:0001556 | oocyte maturation(GO:0001556) |
0.0 | 0.2 | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone(GO:0006120) |
0.0 | 3.4 | GO:0006364 | rRNA processing(GO:0006364) |
0.0 | 3.2 | GO:0035304 | regulation of protein dephosphorylation(GO:0035304) |
0.0 | 2.7 | GO:0032434 | regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032434) |
0.0 | 0.9 | GO:0003341 | cilium movement(GO:0003341) |
0.0 | 0.3 | GO:0022011 | myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292) |
0.0 | 0.1 | GO:2000354 | regulation of ovarian follicle development(GO:2000354) |
0.0 | 0.6 | GO:0070098 | chemokine-mediated signaling pathway(GO:0070098) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
3.0 | 9.1 | GO:0034774 | secretory granule lumen(GO:0034774) cytoplasmic membrane-bounded vesicle lumen(GO:0060205) |
1.3 | 6.4 | GO:0031838 | haptoglobin-hemoglobin complex(GO:0031838) |
0.5 | 2.7 | GO:0005683 | U7 snRNP(GO:0005683) pICln-Sm protein complex(GO:0034715) |
0.5 | 7.1 | GO:0097512 | cardiac myofibril(GO:0097512) |
0.5 | 2.9 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
0.5 | 4.8 | GO:0000783 | telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783) |
0.3 | 4.2 | GO:0005861 | troponin complex(GO:0005861) |
0.3 | 1.0 | GO:0031251 | PAN complex(GO:0031251) |
0.2 | 0.2 | GO:0055087 | Ski complex(GO:0055087) |
0.2 | 1.4 | GO:0005672 | transcription factor TFIIA complex(GO:0005672) |
0.2 | 1.4 | GO:0002139 | stereocilia coupling link(GO:0002139) |
0.2 | 3.4 | GO:0035327 | transcriptionally active chromatin(GO:0035327) |
0.2 | 1.7 | GO:0031931 | TORC1 complex(GO:0031931) |
0.1 | 2.9 | GO:0032433 | filopodium tip(GO:0032433) |
0.1 | 1.2 | GO:0005577 | fibrinogen complex(GO:0005577) |
0.1 | 1.2 | GO:0005742 | mitochondrial outer membrane translocase complex(GO:0005742) |
0.1 | 1.0 | GO:0061574 | ASAP complex(GO:0061574) |
0.1 | 0.6 | GO:0031314 | extrinsic component of mitochondrial inner membrane(GO:0031314) |
0.1 | 4.5 | GO:0097440 | apical dendrite(GO:0097440) |
0.1 | 3.6 | GO:0005771 | multivesicular body(GO:0005771) |
0.1 | 8.4 | GO:0005643 | nuclear pore(GO:0005643) |
0.1 | 1.4 | GO:0001673 | male germ cell nucleus(GO:0001673) |
0.1 | 0.9 | GO:0016342 | catenin complex(GO:0016342) |
0.1 | 0.9 | GO:0036157 | outer dynein arm(GO:0036157) |
0.1 | 3.6 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
0.1 | 3.3 | GO:0045171 | intercellular bridge(GO:0045171) |
0.1 | 0.3 | GO:0005914 | spot adherens junction(GO:0005914) |
0.0 | 1.8 | GO:0030131 | clathrin adaptor complex(GO:0030131) |
0.0 | 3.4 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
0.0 | 1.4 | GO:0005721 | pericentric heterochromatin(GO:0005721) |
0.0 | 0.5 | GO:0030126 | COPI vesicle coat(GO:0030126) |
0.0 | 2.2 | GO:0034707 | chloride channel complex(GO:0034707) |
0.0 | 13.5 | GO:0016324 | apical plasma membrane(GO:0016324) |
0.0 | 0.5 | GO:0005686 | U2 snRNP(GO:0005686) |
0.0 | 0.6 | GO:0044292 | dendrite terminus(GO:0044292) |
0.0 | 0.3 | GO:0031415 | NatA complex(GO:0031415) |
0.0 | 0.9 | GO:0000314 | organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763) |
0.0 | 4.5 | GO:0031225 | anchored component of membrane(GO:0031225) |
0.0 | 0.6 | GO:1902562 | NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562) |
0.0 | 4.4 | GO:0005741 | mitochondrial outer membrane(GO:0005741) |
0.0 | 3.2 | GO:0005923 | bicellular tight junction(GO:0005923) |
0.0 | 2.9 | GO:0030018 | Z disc(GO:0030018) |
0.0 | 0.9 | GO:0030315 | T-tubule(GO:0030315) |
0.0 | 0.2 | GO:0070578 | RISC-loading complex(GO:0070578) |
0.0 | 2.0 | GO:0005814 | centriole(GO:0005814) |
0.0 | 1.9 | GO:0001725 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
0.0 | 1.5 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
0.0 | 1.8 | GO:0016591 | DNA-directed RNA polymerase II, holoenzyme(GO:0016591) |
0.0 | 2.2 | GO:0043204 | perikaryon(GO:0043204) |
0.0 | 1.1 | GO:0071013 | catalytic step 2 spliceosome(GO:0071013) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.6 | 6.4 | GO:0031720 | haptoglobin binding(GO:0031720) |
1.3 | 3.8 | GO:0045353 | interleukin-1, Type II receptor binding(GO:0005151) interleukin-1 Type I receptor antagonist activity(GO:0045352) interleukin-1 Type II receptor antagonist activity(GO:0045353) |
1.1 | 4.5 | GO:0003884 | D-amino-acid oxidase activity(GO:0003884) |
0.9 | 3.6 | GO:0061575 | cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575) |
0.8 | 8.4 | GO:0005049 | nuclear export signal receptor activity(GO:0005049) |
0.7 | 3.4 | GO:0004668 | protein-arginine deiminase activity(GO:0004668) |
0.5 | 3.6 | GO:0052851 | ferric-chelate reductase activity(GO:0000293) cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851) |
0.4 | 2.9 | GO:0035727 | lysophosphatidic acid binding(GO:0035727) |
0.3 | 1.7 | GO:0001875 | lipopolysaccharide receptor activity(GO:0001875) |
0.3 | 2.3 | GO:0019808 | polyamine binding(GO:0019808) |
0.2 | 1.2 | GO:0015288 | porin activity(GO:0015288) |
0.1 | 3.2 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
0.1 | 6.7 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
0.1 | 4.3 | GO:0000993 | RNA polymerase II core binding(GO:0000993) |
0.1 | 2.9 | GO:0003746 | translation elongation factor activity(GO:0003746) |
0.1 | 4.8 | GO:0042162 | telomeric DNA binding(GO:0042162) |
0.1 | 6.0 | GO:0045182 | translation regulator activity(GO:0045182) |
0.1 | 1.9 | GO:0032036 | myosin heavy chain binding(GO:0032036) |
0.1 | 5.5 | GO:0015485 | cholesterol binding(GO:0015485) |
0.1 | 0.9 | GO:0051525 | NFAT protein binding(GO:0051525) |
0.1 | 2.5 | GO:0008198 | ferrous iron binding(GO:0008198) |
0.1 | 1.1 | GO:0045294 | alpha-catenin binding(GO:0045294) |
0.1 | 1.4 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
0.1 | 3.2 | GO:0004864 | protein phosphatase inhibitor activity(GO:0004864) |
0.1 | 2.0 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
0.1 | 11.4 | GO:0008201 | heparin binding(GO:0008201) |
0.1 | 9.4 | GO:0003774 | motor activity(GO:0003774) |
0.1 | 1.4 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
0.1 | 1.5 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
0.1 | 1.0 | GO:0004535 | poly(A)-specific ribonuclease activity(GO:0004535) |
0.0 | 0.6 | GO:0016500 | protein-hormone receptor activity(GO:0016500) |
0.0 | 0.1 | GO:0004802 | transketolase activity(GO:0004802) |
0.0 | 4.6 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
0.0 | 3.2 | GO:0070491 | repressing transcription factor binding(GO:0070491) |
0.0 | 1.1 | GO:0017025 | TBP-class protein binding(GO:0017025) |
0.0 | 0.2 | GO:0070883 | ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296) pre-miRNA binding(GO:0070883) |
0.0 | 2.9 | GO:0004197 | cysteine-type endopeptidase activity(GO:0004197) |
0.0 | 3.4 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
0.0 | 0.6 | GO:0043236 | laminin binding(GO:0043236) |
0.0 | 2.9 | GO:0005178 | integrin binding(GO:0005178) |
0.0 | 0.6 | GO:0042975 | peroxisome proliferator activated receptor binding(GO:0042975) |
0.0 | 3.8 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
0.0 | 0.6 | GO:0048020 | CCR chemokine receptor binding(GO:0048020) |
0.0 | 2.2 | GO:0005254 | chloride channel activity(GO:0005254) |
0.0 | 0.1 | GO:0016971 | flavin-linked sulfhydryl oxidase activity(GO:0016971) |
0.0 | 1.6 | GO:0016765 | transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765) |
0.0 | 1.4 | GO:0004004 | RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004) |
0.0 | 0.3 | GO:0004596 | peptide alpha-N-acetyltransferase activity(GO:0004596) |
0.0 | 1.8 | GO:0008565 | protein transporter activity(GO:0008565) |
0.0 | 0.4 | GO:0005310 | dicarboxylic acid transmembrane transporter activity(GO:0005310) |
0.0 | 0.9 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
0.0 | 0.0 | GO:0030160 | GKAP/Homer scaffold activity(GO:0030160) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 3.5 | SA CASPASE CASCADE | Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade. |
0.1 | 18.3 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
0.1 | 3.6 | PID FOXM1 PATHWAY | FOXM1 transcription factor network |
0.1 | 3.8 | PID IL1 PATHWAY | IL1-mediated signaling events |
0.0 | 3.4 | PID AJDISS 2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
0.0 | 1.5 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
0.0 | 2.0 | PID MYC REPRESS PATHWAY | Validated targets of C-MYC transcriptional repression |
0.0 | 3.6 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
0.0 | 1.7 | PID ERA GENOMIC PATHWAY | Validated nuclear estrogen receptor alpha network |
0.0 | 1.0 | PID HEDGEHOG GLI PATHWAY | Hedgehog signaling events mediated by Gli proteins |
0.0 | 3.1 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.8 | 18.3 | REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS | Genes involved in Termination of O-glycan biosynthesis |
0.2 | 2.7 | REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS | Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs |
0.2 | 2.6 | REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX | Genes involved in Association of licensing factors with the pre-replicative complex |
0.1 | 5.9 | REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D | Genes involved in Metabolism of steroid hormones and vitamins A and D |
0.1 | 1.8 | REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION | Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression |
0.1 | 1.5 | REACTOME ACTIVATION OF RAC | Genes involved in Activation of Rac |
0.1 | 3.6 | REACTOME G1 PHASE | Genes involved in G1 Phase |
0.1 | 4.2 | REACTOME STRIATED MUSCLE CONTRACTION | Genes involved in Striated Muscle Contraction |
0.1 | 3.8 | REACTOME IL1 SIGNALING | Genes involved in Interleukin-1 signaling |
0.1 | 2.6 | REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING | Genes involved in Transferrin endocytosis and recycling |
0.1 | 1.6 | REACTOME DEADENYLATION OF MRNA | Genes involved in Deadenylation of mRNA |
0.0 | 6.3 | REACTOME TRANSLATION | Genes involved in Translation |
0.0 | 0.9 | REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT | Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT) |
0.0 | 1.7 | REACTOME INTERFERON GAMMA SIGNALING | Genes involved in Interferon gamma signaling |
0.0 | 0.2 | REACTOME REGULATORY RNA PATHWAYS | Genes involved in Regulatory RNA pathways |
0.0 | 0.2 | REACTOME COPI MEDIATED TRANSPORT | Genes involved in COPI Mediated Transport |
0.0 | 3.3 | REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES | Genes involved in Metabolism of amino acids and derivatives |