avrg: GSE58827: Dynamics of the Mouse Liver
Gene Symbol | Gene ID | Gene Info |
---|---|---|
Srf
|
ENSMUSG00000015605.5 | serum response factor |
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Srf | mm10_v2_chr17_-_46556158_46556188 | 0.36 | 3.0e-02 | Click! |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.2 | 18.0 | GO:0038028 | insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) |
1.7 | 23.1 | GO:0014866 | skeletal myofibril assembly(GO:0014866) |
0.7 | 2.2 | GO:0008588 | release of cytoplasmic sequestered NF-kappaB(GO:0008588) |
0.6 | 1.9 | GO:0071460 | cellular response to cell-matrix adhesion(GO:0071460) |
0.5 | 1.6 | GO:0055011 | atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014) |
0.4 | 2.6 | GO:0060931 | sinoatrial node cell development(GO:0060931) |
0.4 | 1.7 | GO:1902303 | negative regulation of potassium ion export(GO:1902303) |
0.3 | 1.0 | GO:1902283 | negative regulation of primary amine oxidase activity(GO:1902283) |
0.3 | 1.0 | GO:0090158 | endoplasmic reticulum membrane organization(GO:0090158) |
0.3 | 1.4 | GO:0071899 | negative regulation of interleukin-13 production(GO:0032696) trachea submucosa development(GO:0061152) trachea gland development(GO:0061153) odontoblast differentiation(GO:0071895) regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899) |
0.3 | 3.4 | GO:0071688 | striated muscle myosin thick filament assembly(GO:0071688) |
0.3 | 3.9 | GO:0048739 | cardiac muscle fiber development(GO:0048739) |
0.3 | 1.0 | GO:0045362 | regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362) |
0.3 | 1.2 | GO:1902896 | terminal web assembly(GO:1902896) |
0.2 | 0.9 | GO:1903764 | regulation of potassium ion export across plasma membrane(GO:1903764) |
0.2 | 0.7 | GO:2000845 | positive regulation of androgen secretion(GO:2000836) positive regulation of testosterone secretion(GO:2000845) |
0.2 | 1.7 | GO:0030579 | ubiquitin-dependent SMAD protein catabolic process(GO:0030579) |
0.2 | 0.8 | GO:1900377 | negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377) |
0.2 | 0.6 | GO:0021666 | rhombomere formation(GO:0021594) rhombomere 3 formation(GO:0021660) rhombomere 5 morphogenesis(GO:0021664) rhombomere 5 formation(GO:0021666) |
0.2 | 0.5 | GO:0000973 | posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973) |
0.1 | 0.1 | GO:1903918 | regulation of actin filament severing(GO:1903918) negative regulation of actin filament severing(GO:1903919) |
0.1 | 7.7 | GO:0045214 | sarcomere organization(GO:0045214) |
0.1 | 1.2 | GO:0010739 | positive regulation of protein kinase A signaling(GO:0010739) |
0.1 | 0.6 | GO:0006116 | NADH oxidation(GO:0006116) |
0.1 | 0.5 | GO:0050915 | sensory perception of sour taste(GO:0050915) |
0.1 | 1.3 | GO:0035970 | peptidyl-threonine dephosphorylation(GO:0035970) |
0.1 | 0.3 | GO:1901491 | negative regulation of lymphangiogenesis(GO:1901491) |
0.1 | 3.2 | GO:0002026 | regulation of the force of heart contraction(GO:0002026) |
0.1 | 2.8 | GO:0001706 | endoderm formation(GO:0001706) |
0.1 | 0.9 | GO:0090266 | regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504) |
0.1 | 3.6 | GO:0010718 | positive regulation of epithelial to mesenchymal transition(GO:0010718) |
0.1 | 3.7 | GO:0042398 | cellular modified amino acid biosynthetic process(GO:0042398) |
0.1 | 1.0 | GO:0050765 | negative regulation of phagocytosis(GO:0050765) |
0.1 | 0.4 | GO:0007296 | vitellogenesis(GO:0007296) |
0.0 | 0.9 | GO:0044247 | glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247) |
0.0 | 0.2 | GO:0038044 | transforming growth factor-beta secretion(GO:0038044) |
0.0 | 0.3 | GO:1902166 | negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902166) |
0.0 | 0.1 | GO:0015766 | disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772) |
0.0 | 0.3 | GO:1901844 | regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844) |
0.0 | 0.5 | GO:0000083 | regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083) |
0.0 | 0.5 | GO:0001553 | luteinization(GO:0001553) |
0.0 | 0.4 | GO:0048312 | intracellular distribution of mitochondria(GO:0048312) |
0.0 | 1.7 | GO:0070527 | platelet aggregation(GO:0070527) |
0.0 | 0.1 | GO:0042078 | germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728) |
0.0 | 0.3 | GO:0021540 | corpus callosum morphogenesis(GO:0021540) |
0.0 | 0.8 | GO:0051290 | protein heterotetramerization(GO:0051290) |
0.0 | 0.7 | GO:0006414 | translational elongation(GO:0006414) |
0.0 | 0.2 | GO:0035994 | response to muscle stretch(GO:0035994) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 1.7 | GO:1902937 | inward rectifier potassium channel complex(GO:1902937) |
0.4 | 3.6 | GO:0016012 | sarcoglycan complex(GO:0016012) |
0.3 | 1.0 | GO:0014701 | junctional sarcoplasmic reticulum membrane(GO:0014701) |
0.3 | 13.2 | GO:0005865 | striated muscle thin filament(GO:0005865) |
0.2 | 5.7 | GO:0005859 | muscle myosin complex(GO:0005859) |
0.2 | 3.7 | GO:0043034 | costamere(GO:0043034) |
0.2 | 0.5 | GO:0044614 | nuclear pore cytoplasmic filaments(GO:0044614) |
0.1 | 2.2 | GO:0016460 | myosin II complex(GO:0016460) |
0.1 | 1.4 | GO:1990907 | beta-catenin-TCF complex(GO:1990907) |
0.1 | 23.6 | GO:0031674 | I band(GO:0031674) |
0.1 | 0.7 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
0.1 | 0.9 | GO:0042629 | mast cell granule(GO:0042629) |
0.1 | 0.5 | GO:0097504 | Gemini of coiled bodies(GO:0097504) |
0.1 | 0.8 | GO:0031672 | A band(GO:0031672) |
0.1 | 0.2 | GO:0034685 | integrin alphav-beta6 complex(GO:0034685) |
0.1 | 1.2 | GO:0032433 | filopodium tip(GO:0032433) |
0.1 | 1.1 | GO:0030285 | integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563) |
0.0 | 1.7 | GO:0090544 | BAF-type complex(GO:0090544) |
0.0 | 0.9 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
0.0 | 0.4 | GO:0031315 | extrinsic component of mitochondrial outer membrane(GO:0031315) |
0.0 | 2.6 | GO:0016328 | lateral plasma membrane(GO:0016328) |
0.0 | 0.2 | GO:0035976 | AP1 complex(GO:0035976) |
0.0 | 0.2 | GO:0031466 | Cul5-RING ubiquitin ligase complex(GO:0031466) |
0.0 | 0.1 | GO:0016602 | CCAAT-binding factor complex(GO:0016602) |
0.0 | 4.8 | GO:0000139 | Golgi membrane(GO:0000139) |
0.0 | 3.7 | GO:0031965 | nuclear membrane(GO:0031965) |
0.0 | 0.3 | GO:0005682 | U5 snRNP(GO:0005682) |
0.0 | 19.0 | GO:0005615 | extracellular space(GO:0005615) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.6 | 3.7 | GO:0004111 | creatine kinase activity(GO:0004111) |
0.5 | 18.0 | GO:0043539 | insulin-like growth factor receptor binding(GO:0005159) protein serine/threonine kinase activator activity(GO:0043539) |
0.4 | 2.3 | GO:0030899 | calcium-dependent ATPase activity(GO:0030899) |
0.3 | 1.0 | GO:0052594 | tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596) |
0.3 | 7.8 | GO:0051371 | muscle alpha-actinin binding(GO:0051371) |
0.3 | 5.3 | GO:0005523 | tropomyosin binding(GO:0005523) |
0.3 | 1.7 | GO:1902282 | phosphorelay sensor kinase activity(GO:0000155) voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282) |
0.3 | 4.1 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
0.2 | 0.9 | GO:0008184 | glycogen phosphorylase activity(GO:0008184) |
0.2 | 1.7 | GO:0048495 | Roundabout binding(GO:0048495) |
0.2 | 1.4 | GO:0030284 | estrogen receptor activity(GO:0030284) |
0.2 | 0.6 | GO:0004090 | carbonyl reductase (NADPH) activity(GO:0004090) |
0.1 | 1.2 | GO:0035727 | lysophosphatidic acid binding(GO:0035727) |
0.1 | 0.8 | GO:0008273 | calcium, potassium:sodium antiporter activity(GO:0008273) |
0.1 | 1.0 | GO:0044729 | hemi-methylated DNA-binding(GO:0044729) |
0.1 | 11.8 | GO:0017022 | myosin binding(GO:0017022) |
0.1 | 0.8 | GO:0005087 | Ran guanyl-nucleotide exchange factor activity(GO:0005087) |
0.1 | 1.1 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
0.1 | 1.4 | GO:0008179 | adenylate cyclase binding(GO:0008179) |
0.1 | 0.9 | GO:0051428 | peptide hormone receptor binding(GO:0051428) |
0.1 | 2.6 | GO:0030552 | cAMP binding(GO:0030552) |
0.1 | 1.9 | GO:0001968 | fibronectin binding(GO:0001968) |
0.0 | 1.9 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
0.0 | 0.2 | GO:0005223 | intracellular cGMP activated cation channel activity(GO:0005223) |
0.0 | 0.1 | GO:0019912 | cyclin-dependent protein kinase activating kinase activity(GO:0019912) |
0.0 | 0.5 | GO:0015280 | ligand-gated sodium channel activity(GO:0015280) |
0.0 | 0.4 | GO:0004439 | phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439) |
0.0 | 4.3 | GO:0005178 | integrin binding(GO:0005178) |
0.0 | 0.1 | GO:0015154 | sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157) |
0.0 | 0.3 | GO:0046974 | histone methyltransferase activity (H3-K9 specific)(GO:0046974) |
0.0 | 0.7 | GO:0003746 | translation elongation factor activity(GO:0003746) |
0.0 | 2.5 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
0.0 | 0.9 | GO:0003785 | actin monomer binding(GO:0003785) |
0.0 | 0.6 | GO:0004435 | phosphatidylinositol phospholipase C activity(GO:0004435) |
0.0 | 0.5 | GO:0004115 | 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) |
0.0 | 0.3 | GO:0008307 | structural constituent of muscle(GO:0008307) |
0.0 | 0.5 | GO:0017056 | structural constituent of nuclear pore(GO:0017056) |
0.0 | 0.4 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
0.0 | 0.6 | GO:0071837 | HMG box domain binding(GO:0071837) |
0.0 | 0.1 | GO:0043495 | protein anchor(GO:0043495) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 17.9 | PID AJDISS 2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
0.1 | 7.0 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
0.1 | 8.3 | PID RHOA PATHWAY | RhoA signaling pathway |
0.1 | 1.0 | PID PRL SIGNALING EVENTS PATHWAY | Signaling events mediated by PRL |
0.1 | 1.9 | PID AVB3 OPN PATHWAY | Osteopontin-mediated events |
0.1 | 1.6 | PID HDAC CLASSIII PATHWAY | Signaling events mediated by HDAC Class III |
0.0 | 3.7 | PID RB 1PATHWAY | Regulation of retinoblastoma protein |
0.0 | 1.3 | PID ATF2 PATHWAY | ATF-2 transcription factor network |
0.0 | 1.2 | PID ILK PATHWAY | Integrin-linked kinase signaling |
0.0 | 1.4 | PID AP1 PATHWAY | AP-1 transcription factor network |
0.0 | 1.6 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
0.0 | 1.4 | PID CMYB PATHWAY | C-MYB transcription factor network |
0.0 | 0.6 | PID IL4 2PATHWAY | IL4-mediated signaling events |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.9 | 18.0 | REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
0.2 | 10.5 | REACTOME STRIATED MUSCLE CONTRACTION | Genes involved in Striated Muscle Contraction |
0.2 | 5.4 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
0.1 | 0.9 | REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION | Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression |
0.1 | 1.9 | REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX | Genes involved in Degradation of the extracellular matrix |
0.1 | 0.9 | REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS | Genes involved in Glycogen breakdown (glycogenolysis) |
0.0 | 1.7 | REACTOME VOLTAGE GATED POTASSIUM CHANNELS | Genes involved in Voltage gated Potassium channels |
0.0 | 3.7 | REACTOME PPARA ACTIVATES GENE EXPRESSION | Genes involved in PPARA Activates Gene Expression |
0.0 | 0.7 | REACTOME PACKAGING OF TELOMERE ENDS | Genes involved in Packaging Of Telomere Ends |
0.0 | 0.6 | REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |