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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for UAAGACG

Z-value: 0.44

Motif logo

miRNA associated with seed UAAGACG

NamemiRBASE accession
MIMAT0000520
MIMAT0004939

Activity profile of UAAGACG motif

Sorted Z-values of UAAGACG motif

Network of associatons between targets according to the STRING database.

First level regulatory network of UAAGACG

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.7 GO:0010587 miRNA catabolic process(GO:0010587)
0.1 0.9 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.1 0.3 GO:0070650 actin filament bundle distribution(GO:0070650)
0.1 0.3 GO:0010615 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.1 0.6 GO:0006265 DNA topological change(GO:0006265)
0.1 0.2 GO:0042275 error-free postreplication DNA repair(GO:0042275)
0.1 0.3 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.1 0.9 GO:0035988 chondrocyte proliferation(GO:0035988)
0.0 0.5 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.0 0.4 GO:0010764 negative regulation of fibroblast migration(GO:0010764) negative regulation of cytokine production involved in inflammatory response(GO:1900016)
0.0 0.8 GO:0051984 positive regulation of chromosome segregation(GO:0051984)
0.0 0.3 GO:0051256 mitotic spindle elongation(GO:0000022) mitotic spindle midzone assembly(GO:0051256)
0.0 0.2 GO:0071493 cellular response to UV-B(GO:0071493)
0.0 0.2 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.2 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.3 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.4 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.2 GO:2000973 regulation of pro-B cell differentiation(GO:2000973)
0.0 0.7 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.5 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.0 0.4 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.1 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0 0.4 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0 0.2 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 0.1 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0030905 retromer, tubulation complex(GO:0030905)
0.1 0.6 GO:0001651 dense fibrillar component(GO:0001651)
0.1 0.4 GO:0005955 calcineurin complex(GO:0005955)
0.1 0.2 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.1 0.2 GO:0070557 PCNA-p21 complex(GO:0070557)
0.0 0.3 GO:0097513 myosin II filament(GO:0097513)
0.0 0.3 GO:0001740 Barr body(GO:0001740)
0.0 1.3 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.9 GO:0051233 spindle midzone(GO:0051233)
0.0 0.4 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.1 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.2 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.4 GO:0035869 ciliary transition zone(GO:0035869)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0097100 supercoiled DNA binding(GO:0097100)
0.1 0.4 GO:0031849 olfactory receptor binding(GO:0031849)
0.1 0.3 GO:1990460 leptin receptor binding(GO:1990460)
0.1 0.4 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 0.2 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.0 0.7 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 1.0 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.2 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.5 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.2 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.3 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.1 GO:0001069 regulatory region RNA binding(GO:0001069)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.9 PID ATR PATHWAY ATR signaling pathway
0.0 0.4 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 1.7 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.7 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.5 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.3 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.7 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.3 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.5 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.2 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol