avrg: GSE58827: Dynamics of the Mouse Liver
Gene Symbol | Gene ID | Gene Info |
---|---|---|
Gsx2
|
ENSMUSG00000035946.6 | GS homeobox 2 |
Hoxd3
|
ENSMUSG00000079277.3 | homeobox D3 |
Vax1
|
ENSMUSG00000006270.6 | ventral anterior homeobox 1 |
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Vax1 | mm10_v2_chr19_-_59170978_59170978 | -0.57 | 2.8e-04 | Click! |
Hoxd3 | mm10_v2_chr2_+_74711911_74711939 | -0.39 | 1.8e-02 | Click! |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.3 | 9.2 | GO:0002415 | immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415) |
1.6 | 4.8 | GO:1903919 | regulation of actin filament severing(GO:1903918) negative regulation of actin filament severing(GO:1903919) |
1.3 | 3.8 | GO:0060995 | cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204) |
1.0 | 2.9 | GO:0018879 | biphenyl metabolic process(GO:0018879) |
0.7 | 2.7 | GO:0016062 | adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367) |
0.6 | 8.4 | GO:0015747 | urate transport(GO:0015747) |
0.4 | 1.8 | GO:0071596 | ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596) |
0.3 | 2.8 | GO:0019532 | oxalate transport(GO:0019532) |
0.3 | 1.2 | GO:0043490 | malate-aspartate shuttle(GO:0043490) |
0.3 | 0.8 | GO:0035880 | embryonic nail plate morphogenesis(GO:0035880) |
0.2 | 0.7 | GO:1902498 | regulation of protein autoubiquitination(GO:1902498) |
0.2 | 1.4 | GO:0033762 | response to glucagon(GO:0033762) |
0.2 | 1.6 | GO:0006933 | negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933) |
0.2 | 1.3 | GO:0006083 | acetate metabolic process(GO:0006083) |
0.2 | 0.9 | GO:1904395 | positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) |
0.2 | 2.7 | GO:0048733 | sebaceous gland development(GO:0048733) |
0.2 | 1.9 | GO:0052696 | flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697) |
0.2 | 2.1 | GO:1901898 | negative regulation of relaxation of cardiac muscle(GO:1901898) |
0.2 | 2.7 | GO:0048672 | positive regulation of collateral sprouting(GO:0048672) |
0.1 | 0.4 | GO:1903189 | enzyme active site formation via L-cysteine sulfinic acid(GO:0018323) primary alcohol biosynthetic process(GO:0034309) cellular response to glyoxal(GO:0036471) glycolate biosynthetic process(GO:0046295) negative regulation of TRAIL-activated apoptotic signaling pathway(GO:1903122) regulation of pyrroline-5-carboxylate reductase activity(GO:1903167) positive regulation of pyrroline-5-carboxylate reductase activity(GO:1903168) regulation of tyrosine 3-monooxygenase activity(GO:1903176) positive regulation of tyrosine 3-monooxygenase activity(GO:1903178) L-dopa metabolic process(GO:1903184) L-dopa biosynthetic process(GO:1903185) glyoxal metabolic process(GO:1903189) regulation of L-dopa biosynthetic process(GO:1903195) positive regulation of L-dopa biosynthetic process(GO:1903197) regulation of L-dopa decarboxylase activity(GO:1903198) positive regulation of L-dopa decarboxylase activity(GO:1903200) positive regulation of cellular amino acid biosynthetic process(GO:2000284) |
0.1 | 1.3 | GO:0002098 | tRNA wobble uridine modification(GO:0002098) |
0.1 | 0.4 | GO:0030091 | protein repair(GO:0030091) |
0.1 | 0.6 | GO:0070562 | regulation of vitamin D receptor signaling pathway(GO:0070562) |
0.1 | 0.5 | GO:0051012 | microtubule sliding(GO:0051012) |
0.1 | 0.6 | GO:0046552 | eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552) |
0.1 | 0.7 | GO:0061732 | mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732) |
0.1 | 0.4 | GO:0070173 | regulation of enamel mineralization(GO:0070173) |
0.1 | 1.3 | GO:0030322 | stabilization of membrane potential(GO:0030322) |
0.1 | 0.4 | GO:0043985 | histone H4-R3 methylation(GO:0043985) |
0.1 | 0.6 | GO:0097460 | positive regulation of oligodendrocyte progenitor proliferation(GO:0070447) ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707) |
0.1 | 0.9 | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone(GO:0006120) |
0.1 | 2.7 | GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184) |
0.1 | 0.6 | GO:0034382 | chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830) |
0.1 | 0.6 | GO:0071372 | cellular response to follicle-stimulating hormone stimulus(GO:0071372) |
0.1 | 0.8 | GO:0036159 | inner dynein arm assembly(GO:0036159) |
0.1 | 1.6 | GO:0048240 | sperm capacitation(GO:0048240) |
0.1 | 0.2 | GO:0006421 | asparaginyl-tRNA aminoacylation(GO:0006421) |
0.0 | 0.3 | GO:0009235 | cobalamin metabolic process(GO:0009235) |
0.0 | 0.4 | GO:0030035 | microspike assembly(GO:0030035) |
0.0 | 0.1 | GO:2000616 | negative regulation of histone H3-K9 acetylation(GO:2000616) |
0.0 | 0.6 | GO:0019321 | pentose metabolic process(GO:0019321) |
0.0 | 1.3 | GO:0019373 | epoxygenase P450 pathway(GO:0019373) |
0.0 | 0.2 | GO:0001878 | response to yeast(GO:0001878) |
0.0 | 0.7 | GO:0006516 | glycoprotein catabolic process(GO:0006516) |
0.0 | 1.4 | GO:0007339 | binding of sperm to zona pellucida(GO:0007339) |
0.0 | 0.4 | GO:1902083 | negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083) |
0.0 | 0.3 | GO:1900194 | negative regulation of oocyte maturation(GO:1900194) |
0.0 | 0.2 | GO:0070317 | negative regulation of G0 to G1 transition(GO:0070317) |
0.0 | 0.1 | GO:0015888 | thiamine transport(GO:0015888) |
0.0 | 0.3 | GO:0097151 | positive regulation of inhibitory postsynaptic potential(GO:0097151) |
0.0 | 0.1 | GO:0016332 | establishment or maintenance of polarity of embryonic epithelium(GO:0016332) |
0.0 | 0.4 | GO:0006107 | oxaloacetate metabolic process(GO:0006107) |
0.0 | 0.3 | GO:1904861 | excitatory synapse assembly(GO:1904861) |
0.0 | 0.5 | GO:0032754 | positive regulation of interleukin-5 production(GO:0032754) |
0.0 | 0.2 | GO:0050955 | thermoception(GO:0050955) |
0.0 | 0.5 | GO:0051044 | positive regulation of membrane protein ectodomain proteolysis(GO:0051044) |
0.0 | 1.3 | GO:0043029 | T cell homeostasis(GO:0043029) |
0.0 | 1.3 | GO:0003301 | physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049) |
0.0 | 0.9 | GO:0042773 | ATP synthesis coupled electron transport(GO:0042773) |
0.0 | 0.3 | GO:0048387 | negative regulation of retinoic acid receptor signaling pathway(GO:0048387) |
0.0 | 0.3 | GO:0098719 | sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118) |
0.0 | 0.1 | GO:1904742 | regulation of telomeric DNA binding(GO:1904742) |
0.0 | 0.3 | GO:0031987 | locomotion involved in locomotory behavior(GO:0031987) |
0.0 | 0.5 | GO:0015985 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
0.0 | 0.1 | GO:0001712 | ectodermal cell fate commitment(GO:0001712) |
0.0 | 2.9 | GO:0007601 | visual perception(GO:0007601) |
0.0 | 0.1 | GO:0016560 | protein import into peroxisome matrix, docking(GO:0016560) |
0.0 | 0.1 | GO:0014816 | skeletal muscle satellite cell differentiation(GO:0014816) recognition of apoptotic cell(GO:0043654) |
0.0 | 1.2 | GO:0051489 | regulation of filopodium assembly(GO:0051489) |
0.0 | 0.5 | GO:0051560 | mitochondrial calcium ion homeostasis(GO:0051560) |
0.0 | 0.2 | GO:0000712 | resolution of meiotic recombination intermediates(GO:0000712) |
0.0 | 0.3 | GO:0032331 | negative regulation of chondrocyte differentiation(GO:0032331) |
0.0 | 14.0 | GO:0055114 | oxidation-reduction process(GO:0055114) |
0.0 | 0.6 | GO:0045022 | early endosome to late endosome transport(GO:0045022) |
0.0 | 0.4 | GO:0071801 | regulation of podosome assembly(GO:0071801) |
0.0 | 1.2 | GO:0032024 | positive regulation of insulin secretion(GO:0032024) |
0.0 | 0.8 | GO:0050982 | detection of mechanical stimulus(GO:0050982) |
0.0 | 0.2 | GO:0003215 | cardiac right ventricle morphogenesis(GO:0003215) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 2.9 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
0.2 | 8.7 | GO:0055038 | recycling endosome membrane(GO:0055038) |
0.2 | 1.6 | GO:0000275 | mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261) |
0.1 | 0.4 | GO:0097636 | intrinsic component of autophagosome membrane(GO:0097636) integral component of autophagosome membrane(GO:0097637) |
0.1 | 0.4 | GO:0005967 | mitochondrial pyruvate dehydrogenase complex(GO:0005967) |
0.1 | 1.4 | GO:0045275 | respiratory chain complex III(GO:0045275) |
0.1 | 3.9 | GO:0045095 | keratin filament(GO:0045095) |
0.1 | 0.8 | GO:0033503 | HULC complex(GO:0033503) |
0.1 | 0.6 | GO:0005726 | perichromatin fibrils(GO:0005726) |
0.1 | 0.6 | GO:0070695 | FHF complex(GO:0070695) |
0.1 | 1.6 | GO:0035686 | sperm fibrous sheath(GO:0035686) |
0.1 | 2.1 | GO:0000930 | gamma-tubulin complex(GO:0000930) |
0.1 | 0.3 | GO:0045254 | pyruvate dehydrogenase complex(GO:0045254) |
0.1 | 0.9 | GO:0016600 | flotillin complex(GO:0016600) |
0.1 | 0.6 | GO:1990712 | HFE-transferrin receptor complex(GO:1990712) |
0.1 | 0.7 | GO:0044322 | endoplasmic reticulum quality control compartment(GO:0044322) |
0.0 | 3.3 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
0.0 | 3.4 | GO:0070469 | respiratory chain(GO:0070469) |
0.0 | 0.5 | GO:0000276 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) |
0.0 | 0.3 | GO:0036156 | inner dynein arm(GO:0036156) |
0.0 | 4.2 | GO:0030018 | Z disc(GO:0030018) |
0.0 | 2.4 | GO:0031526 | brush border membrane(GO:0031526) |
0.0 | 0.2 | GO:0000812 | Swr1 complex(GO:0000812) |
0.0 | 0.5 | GO:0016581 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
0.0 | 0.6 | GO:0034364 | high-density lipoprotein particle(GO:0034364) |
0.0 | 0.1 | GO:0017071 | intracellular cyclic nucleotide activated cation channel complex(GO:0017071) |
0.0 | 0.1 | GO:0097550 | transcriptional preinitiation complex(GO:0097550) |
0.0 | 16.7 | GO:0005730 | nucleolus(GO:0005730) |
0.0 | 1.0 | GO:0005882 | intermediate filament(GO:0005882) |
0.0 | 0.3 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
0.0 | 0.5 | GO:0009295 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.0 | 2.9 | GO:0005118 | sevenless binding(GO:0005118) |
0.9 | 9.2 | GO:0019763 | immunoglobulin receptor activity(GO:0019763) |
0.8 | 4.8 | GO:0061629 | RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629) |
0.6 | 13.2 | GO:0004745 | retinol dehydrogenase activity(GO:0004745) |
0.6 | 8.4 | GO:1901702 | urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702) |
0.4 | 1.3 | GO:0019807 | aspartoacylase activity(GO:0019807) |
0.4 | 1.2 | GO:0008113 | peptide-methionine (S)-S-oxide reductase activity(GO:0008113) |
0.3 | 1.6 | GO:0043532 | angiostatin binding(GO:0043532) |
0.2 | 2.7 | GO:0008429 | phosphatidylethanolamine binding(GO:0008429) |
0.2 | 3.6 | GO:0016500 | protein-hormone receptor activity(GO:0016500) |
0.2 | 1.3 | GO:0016300 | tRNA (uracil) methyltransferase activity(GO:0016300) |
0.2 | 0.6 | GO:0019150 | D-ribulokinase activity(GO:0019150) |
0.2 | 1.2 | GO:0015501 | glutamate:sodium symporter activity(GO:0015501) |
0.2 | 1.4 | GO:0008121 | ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681) |
0.2 | 2.8 | GO:0019531 | oxalate transmembrane transporter activity(GO:0019531) |
0.2 | 5.9 | GO:0015020 | glucuronosyltransferase activity(GO:0015020) |
0.1 | 0.7 | GO:0004738 | pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604) |
0.1 | 0.4 | GO:0036470 | tyrosine 3-monooxygenase activator activity(GO:0036470) L-dopa decarboxylase activator activity(GO:0036478) |
0.1 | 1.7 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
0.1 | 0.4 | GO:0033743 | peptide-methionine (R)-S-oxide reductase activity(GO:0033743) |
0.1 | 0.6 | GO:0008970 | phosphatidylcholine 1-acylhydrolase activity(GO:0008970) |
0.1 | 3.0 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
0.1 | 0.6 | GO:0034056 | estrogen response element binding(GO:0034056) |
0.1 | 1.3 | GO:0022841 | potassium ion leak channel activity(GO:0022841) |
0.1 | 0.6 | GO:0072510 | ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510) |
0.1 | 0.6 | GO:0004027 | alcohol sulfotransferase activity(GO:0004027) |
0.1 | 2.5 | GO:0070330 | aromatase activity(GO:0070330) |
0.1 | 1.9 | GO:0042975 | peroxisome proliferator activated receptor binding(GO:0042975) |
0.1 | 0.6 | GO:0005004 | GPI-linked ephrin receptor activity(GO:0005004) |
0.1 | 0.4 | GO:0046912 | transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912) |
0.1 | 0.4 | GO:0045134 | uridine-diphosphatase activity(GO:0045134) |
0.1 | 2.1 | GO:0004115 | 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) |
0.1 | 1.2 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
0.0 | 0.9 | GO:0008392 | arachidonic acid epoxygenase activity(GO:0008392) |
0.0 | 0.3 | GO:0008597 | calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597) |
0.0 | 2.5 | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547) |
0.0 | 0.7 | GO:1904264 | ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264) |
0.0 | 0.5 | GO:0019855 | calcium channel inhibitor activity(GO:0019855) |
0.0 | 0.1 | GO:0015403 | thiamine uptake transmembrane transporter activity(GO:0015403) uptake transmembrane transporter activity(GO:0015563) |
0.0 | 0.1 | GO:0030292 | protein tyrosine kinase inhibitor activity(GO:0030292) |
0.0 | 4.6 | GO:0016853 | isomerase activity(GO:0016853) |
0.0 | 0.3 | GO:0015386 | potassium:proton antiporter activity(GO:0015386) |
0.0 | 0.1 | GO:0005052 | peroxisome matrix targeting signal-1 binding(GO:0005052) |
0.0 | 0.8 | GO:0043014 | alpha-tubulin binding(GO:0043014) |
0.0 | 0.9 | GO:0051959 | dynein light intermediate chain binding(GO:0051959) |
0.0 | 0.1 | GO:0015016 | [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016) |
0.0 | 0.1 | GO:0061665 | SUMO ligase activity(GO:0061665) |
0.0 | 0.7 | GO:0031435 | mitogen-activated protein kinase kinase kinase binding(GO:0031435) |
0.0 | 1.2 | GO:0030507 | spectrin binding(GO:0030507) |
0.0 | 0.0 | GO:0050309 | glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309) |
0.0 | 0.3 | GO:0008432 | JUN kinase binding(GO:0008432) |
0.0 | 0.7 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
0.0 | 0.3 | GO:0005234 | extracellular-glutamate-gated ion channel activity(GO:0005234) |
0.0 | 0.1 | GO:0000990 | transcription factor activity, core RNA polymerase binding(GO:0000990) |
0.0 | 0.5 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
0.0 | 0.1 | GO:0016671 | oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 1.8 | PID ERB GENOMIC PATHWAY | Validated nuclear estrogen receptor beta network |
0.1 | 9.2 | PID IL4 2PATHWAY | IL4-mediated signaling events |
0.1 | 2.7 | PID LIS1 PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
0.1 | 2.5 | PID ARF6 PATHWAY | Arf6 signaling events |
0.0 | 1.2 | PID NETRIN PATHWAY | Netrin-mediated signaling events |
0.0 | 0.6 | PID EPHA FWDPATHWAY | EPHA forward signaling |
0.0 | 0.7 | PID FRA PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
0.0 | 0.3 | PID PDGFRA PATHWAY | PDGFR-alpha signaling pathway |
0.0 | 0.4 | PID ALPHA SYNUCLEIN PATHWAY | Alpha-synuclein signaling |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 2.9 | REACTOME GLUCURONIDATION | Genes involved in Glucuronidation |
0.1 | 0.5 | REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION | Genes involved in Influenza Viral RNA Transcription and Replication |
0.1 | 1.3 | REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS | Genes involved in Tandem pore domain potassium channels |
0.1 | 1.6 | REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING | Genes involved in Formation of ATP by chemiosmotic coupling |
0.1 | 1.2 | REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS | Genes involved in Synthesis of substrates in N-glycan biosythesis |
0.1 | 1.9 | REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE | Genes involved in Cytochrome P450 - arranged by substrate type |
0.1 | 0.8 | REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS | Genes involved in Ionotropic activity of Kainate Receptors |
0.1 | 0.7 | REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX | Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex |
0.0 | 2.1 | REACTOME DARPP 32 EVENTS | Genes involved in DARPP-32 events |
0.0 | 2.7 | REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS | Genes involved in Amino acid and oligopeptide SLC transporters |
0.0 | 2.0 | REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
0.0 | 1.1 | REACTOME SIGNALING BY FGFR1 FUSION MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |
0.0 | 0.6 | REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
0.0 | 1.9 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
0.0 | 2.7 | REACTOME L1CAM INTERACTIONS | Genes involved in L1CAM interactions |
0.0 | 0.4 | REACTOME CITRIC ACID CYCLE TCA CYCLE | Genes involved in Citric acid cycle (TCA cycle) |
0.0 | 1.0 | REACTOME NETRIN1 SIGNALING | Genes involved in Netrin-1 signaling |
0.0 | 0.4 | REACTOME KINESINS | Genes involved in Kinesins |