avrg: GSE58827: Dynamics of the Mouse Liver
Gene Symbol | Gene ID | Gene Info |
---|---|---|
Pax2
|
ENSMUSG00000004231.9 | paired box 2 |
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Pax2 | mm10_v2_chr19_+_44757394_44757394 | -0.27 | 1.1e-01 | Click! |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.9 | 5.7 | GO:0019859 | pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859) |
1.1 | 5.6 | GO:1904721 | regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721) |
1.0 | 3.0 | GO:0035602 | fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604) coronal suture morphogenesis(GO:0060365) |
0.8 | 4.8 | GO:0044375 | regulation of peroxisome size(GO:0044375) |
0.8 | 3.9 | GO:0090038 | negative regulation of protein kinase C signaling(GO:0090038) |
0.8 | 2.3 | GO:0045645 | regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645) |
0.7 | 2.7 | GO:0097498 | endothelial tube lumen extension(GO:0097498) |
0.7 | 2.0 | GO:0018879 | biphenyl metabolic process(GO:0018879) |
0.6 | 1.9 | GO:0043323 | positive regulation of natural killer cell degranulation(GO:0043323) |
0.6 | 2.5 | GO:0014916 | regulation of lung blood pressure(GO:0014916) |
0.6 | 5.9 | GO:0016554 | cytidine to uridine editing(GO:0016554) |
0.6 | 2.2 | GO:0009992 | cellular water homeostasis(GO:0009992) |
0.5 | 2.2 | GO:1904715 | negative regulation of chaperone-mediated autophagy(GO:1904715) |
0.5 | 3.7 | GO:0070495 | regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495) |
0.5 | 2.1 | GO:0016103 | diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653) |
0.5 | 2.0 | GO:0014012 | peripheral nervous system axon regeneration(GO:0014012) negative regulation of glial cell migration(GO:1903976) |
0.5 | 1.5 | GO:0000720 | pyrimidine dimer repair by nucleotide-excision repair(GO:0000720) |
0.5 | 4.6 | GO:0061727 | methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727) |
0.4 | 3.6 | GO:0061084 | negative regulation of protein refolding(GO:0061084) |
0.4 | 1.8 | GO:0003349 | epicardium-derived cardiac endothelial cell differentiation(GO:0003349) |
0.4 | 1.2 | GO:0001982 | baroreceptor response to decreased systemic arterial blood pressure(GO:0001982) |
0.4 | 4.1 | GO:0051256 | mitotic spindle midzone assembly(GO:0051256) positive regulation of ubiquitin protein ligase activity(GO:1904668) |
0.4 | 1.2 | GO:0060399 | positive regulation of growth hormone receptor signaling pathway(GO:0060399) |
0.3 | 1.7 | GO:0072719 | cellular response to cisplatin(GO:0072719) |
0.3 | 2.0 | GO:1900170 | prolactin signaling pathway(GO:0038161) negative regulation of glucocorticoid mediated signaling pathway(GO:1900170) |
0.3 | 2.2 | GO:2000667 | positive regulation of interleukin-5 secretion(GO:2000664) positive regulation of interleukin-13 secretion(GO:2000667) |
0.3 | 1.2 | GO:1904395 | positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) |
0.3 | 1.1 | GO:0010536 | positive regulation of activation of Janus kinase activity(GO:0010536) |
0.3 | 1.1 | GO:0090126 | protein complex assembly involved in synapse maturation(GO:0090126) |
0.3 | 1.8 | GO:0061113 | pancreas morphogenesis(GO:0061113) |
0.2 | 1.2 | GO:0033364 | mast cell secretory granule organization(GO:0033364) |
0.2 | 0.9 | GO:0090283 | regulation of protein glycosylation in Golgi(GO:0090283) |
0.2 | 1.6 | GO:2000510 | positive regulation of dendritic cell chemotaxis(GO:2000510) |
0.2 | 0.6 | GO:0043311 | positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568) |
0.2 | 0.6 | GO:0061743 | motor learning(GO:0061743) |
0.2 | 1.6 | GO:0090219 | negative regulation of lipid kinase activity(GO:0090219) |
0.2 | 4.4 | GO:0048642 | negative regulation of skeletal muscle tissue development(GO:0048642) |
0.2 | 0.8 | GO:0097577 | intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577) |
0.2 | 1.0 | GO:1902683 | regulation of receptor localization to synapse(GO:1902683) |
0.2 | 3.0 | GO:0042407 | cristae formation(GO:0042407) |
0.2 | 0.4 | GO:2000182 | regulation of progesterone biosynthetic process(GO:2000182) |
0.2 | 1.5 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
0.2 | 0.5 | GO:0019858 | cytosine metabolic process(GO:0019858) |
0.2 | 0.9 | GO:0090273 | regulation of somatostatin secretion(GO:0090273) |
0.2 | 1.0 | GO:0015014 | heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014) |
0.2 | 3.4 | GO:0036295 | cellular response to increased oxygen levels(GO:0036295) |
0.2 | 0.5 | GO:0060854 | patterning of lymph vessels(GO:0060854) |
0.2 | 0.5 | GO:0061055 | myotome development(GO:0061055) |
0.1 | 2.5 | GO:0015937 | coenzyme A biosynthetic process(GO:0015937) |
0.1 | 2.2 | GO:2001014 | regulation of skeletal muscle cell differentiation(GO:2001014) |
0.1 | 1.1 | GO:1904628 | response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628) |
0.1 | 1.3 | GO:0071340 | protein localization to microtubule(GO:0035372) skeletal muscle acetylcholine-gated channel clustering(GO:0071340) |
0.1 | 0.5 | GO:0043490 | malate-aspartate shuttle(GO:0043490) |
0.1 | 3.3 | GO:2000310 | regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310) |
0.1 | 3.2 | GO:1990126 | retrograde transport, endosome to plasma membrane(GO:1990126) |
0.1 | 2.4 | GO:0050765 | nucleophagy(GO:0044804) negative regulation of phagocytosis(GO:0050765) |
0.1 | 1.3 | GO:0035878 | nail development(GO:0035878) |
0.1 | 0.8 | GO:0070427 | nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427) |
0.1 | 0.9 | GO:0032510 | endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510) |
0.1 | 0.3 | GO:0003285 | septum secundum development(GO:0003285) cardiac muscle tissue regeneration(GO:0061026) negative regulation of connective tissue replacement(GO:1905204) |
0.1 | 1.6 | GO:0006895 | Golgi to endosome transport(GO:0006895) |
0.1 | 0.8 | GO:0006646 | phosphatidylethanolamine biosynthetic process(GO:0006646) |
0.1 | 4.2 | GO:0001958 | endochondral ossification(GO:0001958) replacement ossification(GO:0036075) |
0.1 | 0.5 | GO:0044828 | negative regulation by host of viral genome replication(GO:0044828) |
0.1 | 2.2 | GO:0031571 | mitotic G1 DNA damage checkpoint(GO:0031571) |
0.1 | 0.9 | GO:0045792 | negative regulation of cell size(GO:0045792) |
0.1 | 1.0 | GO:0060253 | negative regulation of glial cell proliferation(GO:0060253) |
0.1 | 0.6 | GO:2000298 | regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298) |
0.1 | 0.3 | GO:0001827 | inner cell mass cell fate commitment(GO:0001827) |
0.1 | 0.6 | GO:0051503 | adenine nucleotide transport(GO:0051503) |
0.1 | 0.1 | GO:0035964 | COPI-coated vesicle budding(GO:0035964) |
0.1 | 0.2 | GO:0021526 | medial motor column neuron differentiation(GO:0021526) |
0.1 | 1.0 | GO:0090148 | membrane fission(GO:0090148) |
0.1 | 1.4 | GO:0003094 | glomerular filtration(GO:0003094) |
0.1 | 0.2 | GO:0046878 | positive regulation of saliva secretion(GO:0046878) |
0.1 | 0.8 | GO:0090051 | negative regulation of cell migration involved in sprouting angiogenesis(GO:0090051) |
0.1 | 0.7 | GO:0033133 | positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301) |
0.1 | 0.4 | GO:1901029 | negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029) |
0.1 | 0.2 | GO:1901979 | regulation of inward rectifier potassium channel activity(GO:1901979) |
0.1 | 0.4 | GO:0043562 | cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562) |
0.1 | 1.0 | GO:0002024 | diet induced thermogenesis(GO:0002024) |
0.1 | 12.3 | GO:0008643 | carbohydrate transport(GO:0008643) |
0.1 | 0.4 | GO:0070127 | tRNA aminoacylation for mitochondrial protein translation(GO:0070127) |
0.1 | 2.3 | GO:0007032 | endosome organization(GO:0007032) |
0.1 | 0.9 | GO:0070816 | phosphorylation of RNA polymerase II C-terminal domain(GO:0070816) |
0.1 | 0.4 | GO:0006689 | ganglioside catabolic process(GO:0006689) |
0.0 | 0.2 | GO:0045423 | granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0042253) regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045423) |
0.0 | 0.7 | GO:0030277 | maintenance of gastrointestinal epithelium(GO:0030277) |
0.0 | 1.3 | GO:0060009 | Sertoli cell development(GO:0060009) |
0.0 | 0.4 | GO:0031119 | tRNA pseudouridine synthesis(GO:0031119) |
0.0 | 0.0 | GO:0071376 | response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376) |
0.0 | 2.9 | GO:0000045 | autophagosome assembly(GO:0000045) |
0.0 | 1.1 | GO:0032967 | positive regulation of collagen biosynthetic process(GO:0032967) |
0.0 | 0.1 | GO:0046462 | monoacylglycerol metabolic process(GO:0046462) |
0.0 | 0.6 | GO:0043248 | proteasome assembly(GO:0043248) |
0.0 | 1.1 | GO:0045671 | negative regulation of osteoclast differentiation(GO:0045671) |
0.0 | 0.7 | GO:0006309 | apoptotic DNA fragmentation(GO:0006309) |
0.0 | 0.4 | GO:0060040 | retinal bipolar neuron differentiation(GO:0060040) |
0.0 | 0.1 | GO:0061056 | sclerotome development(GO:0061056) |
0.0 | 0.7 | GO:1990001 | inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001) |
0.0 | 1.9 | GO:0045604 | regulation of epidermal cell differentiation(GO:0045604) |
0.0 | 0.6 | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone(GO:0006120) |
0.0 | 0.5 | GO:0002517 | T cell tolerance induction(GO:0002517) |
0.0 | 1.1 | GO:0007638 | mechanosensory behavior(GO:0007638) |
0.0 | 1.4 | GO:0048488 | synaptic vesicle endocytosis(GO:0048488) |
0.0 | 1.9 | GO:0007157 | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157) |
0.0 | 1.7 | GO:0007628 | adult walking behavior(GO:0007628) |
0.0 | 0.8 | GO:0048026 | positive regulation of mRNA splicing, via spliceosome(GO:0048026) |
0.0 | 0.6 | GO:0090023 | positive regulation of neutrophil chemotaxis(GO:0090023) |
0.0 | 1.5 | GO:0030901 | midbrain development(GO:0030901) |
0.0 | 0.1 | GO:1901857 | positive regulation of cellular respiration(GO:1901857) |
0.0 | 0.4 | GO:1904816 | positive regulation of protein localization to chromosome, telomeric region(GO:1904816) |
0.0 | 2.9 | GO:0006821 | chloride transport(GO:0006821) |
0.0 | 1.5 | GO:0051865 | protein autoubiquitination(GO:0051865) |
0.0 | 0.2 | GO:0046784 | viral mRNA export from host cell nucleus(GO:0046784) |
0.0 | 0.1 | GO:0006384 | transcription initiation from RNA polymerase III promoter(GO:0006384) |
0.0 | 2.3 | GO:0000187 | activation of MAPK activity(GO:0000187) |
0.0 | 1.7 | GO:0006986 | response to unfolded protein(GO:0006986) |
0.0 | 0.7 | GO:1900026 | positive regulation of substrate adhesion-dependent cell spreading(GO:1900026) |
0.0 | 0.7 | GO:0060612 | adipose tissue development(GO:0060612) |
0.0 | 0.2 | GO:1904376 | negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376) |
0.0 | 1.6 | GO:0016236 | macroautophagy(GO:0016236) |
0.0 | 0.3 | GO:0071542 | dopaminergic neuron differentiation(GO:0071542) |
0.0 | 0.8 | GO:0008543 | fibroblast growth factor receptor signaling pathway(GO:0008543) |
0.0 | 0.3 | GO:0099517 | anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517) |
0.0 | 0.5 | GO:2001222 | regulation of neuron migration(GO:2001222) |
0.0 | 0.3 | GO:0045838 | positive regulation of membrane potential(GO:0045838) |
0.0 | 0.4 | GO:0001709 | cell fate determination(GO:0001709) |
0.0 | 0.1 | GO:0021942 | radial glia guided migration of Purkinje cell(GO:0021942) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.8 | 3.2 | GO:0030906 | retromer, cargo-selective complex(GO:0030906) |
0.6 | 1.9 | GO:0032010 | phagolysosome(GO:0032010) |
0.4 | 3.9 | GO:0033180 | proton-transporting V-type ATPase, V1 domain(GO:0033180) |
0.3 | 3.0 | GO:0061617 | MICOS complex(GO:0061617) |
0.3 | 1.3 | GO:0032280 | symmetric synapse(GO:0032280) |
0.3 | 12.5 | GO:0080008 | Cul4-RING E3 ubiquitin ligase complex(GO:0080008) |
0.3 | 0.9 | GO:0005899 | insulin receptor complex(GO:0005899) |
0.3 | 1.1 | GO:0005896 | interleukin-6 receptor complex(GO:0005896) |
0.3 | 1.1 | GO:0097129 | cyclin D2-CDK4 complex(GO:0097129) |
0.2 | 1.1 | GO:0033553 | rDNA heterochromatin(GO:0033553) |
0.2 | 2.4 | GO:0000153 | cytoplasmic ubiquitin ligase complex(GO:0000153) |
0.2 | 1.6 | GO:0042824 | MHC class I peptide loading complex(GO:0042824) |
0.2 | 0.5 | GO:0034457 | Mpp10 complex(GO:0034457) |
0.2 | 1.7 | GO:0090571 | RNA polymerase II transcription repressor complex(GO:0090571) |
0.2 | 0.7 | GO:0031084 | BLOC-2 complex(GO:0031084) |
0.2 | 1.3 | GO:0031313 | extrinsic component of endosome membrane(GO:0031313) |
0.2 | 4.8 | GO:0005779 | integral component of peroxisomal membrane(GO:0005779) |
0.1 | 2.2 | GO:0043203 | axon hillock(GO:0043203) apical cortex(GO:0045179) |
0.1 | 2.0 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
0.1 | 1.4 | GO:0044233 | ER-mitochondrion membrane contact site(GO:0044233) |
0.1 | 1.2 | GO:0016600 | flotillin complex(GO:0016600) |
0.1 | 1.3 | GO:1990909 | Wnt signalosome(GO:1990909) |
0.1 | 1.5 | GO:0072546 | ER membrane protein complex(GO:0072546) |
0.1 | 0.9 | GO:0000439 | core TFIIH complex(GO:0000439) |
0.1 | 1.0 | GO:0016272 | prefoldin complex(GO:0016272) |
0.1 | 0.6 | GO:0000322 | storage vacuole(GO:0000322) |
0.1 | 0.9 | GO:0031931 | TORC1 complex(GO:0031931) |
0.1 | 1.3 | GO:1990635 | proximal dendrite(GO:1990635) |
0.1 | 0.7 | GO:0032797 | SMN complex(GO:0032797) |
0.1 | 1.0 | GO:0005662 | DNA replication factor A complex(GO:0005662) |
0.1 | 1.6 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
0.1 | 5.8 | GO:0005776 | autophagosome(GO:0005776) |
0.1 | 1.2 | GO:0098984 | asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984) |
0.1 | 1.1 | GO:0036057 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
0.1 | 0.5 | GO:0070765 | gamma-secretase complex(GO:0070765) |
0.1 | 0.5 | GO:0030991 | intraciliary transport particle A(GO:0030991) |
0.1 | 1.2 | GO:0010369 | chromocenter(GO:0010369) |
0.0 | 0.7 | GO:0032045 | guanyl-nucleotide exchange factor complex(GO:0032045) |
0.0 | 4.2 | GO:0009925 | basal plasma membrane(GO:0009925) |
0.0 | 1.5 | GO:0090544 | BAF-type complex(GO:0090544) |
0.0 | 0.9 | GO:0035327 | transcriptionally active chromatin(GO:0035327) |
0.0 | 0.6 | GO:0035102 | PRC1 complex(GO:0035102) |
0.0 | 10.9 | GO:0000139 | Golgi membrane(GO:0000139) |
0.0 | 2.7 | GO:0005811 | lipid particle(GO:0005811) |
0.0 | 0.4 | GO:0005766 | primary lysosome(GO:0005766) azurophil granule(GO:0042582) |
0.0 | 0.8 | GO:0035145 | exon-exon junction complex(GO:0035145) |
0.0 | 3.0 | GO:0000922 | spindle pole(GO:0000922) |
0.0 | 0.3 | GO:0030123 | AP-3 adaptor complex(GO:0030123) |
0.0 | 0.2 | GO:0000347 | THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445) |
0.0 | 0.6 | GO:0030134 | ER to Golgi transport vesicle(GO:0030134) |
0.0 | 0.9 | GO:0031901 | early endosome membrane(GO:0031901) |
0.0 | 1.4 | GO:0032420 | stereocilium(GO:0032420) |
0.0 | 5.5 | GO:0005759 | mitochondrial matrix(GO:0005759) |
0.0 | 0.8 | GO:0032809 | neuronal cell body membrane(GO:0032809) |
0.0 | 6.2 | GO:0005938 | cell cortex(GO:0005938) |
0.0 | 4.9 | GO:0031965 | nuclear membrane(GO:0031965) |
0.0 | 6.7 | GO:0005789 | endoplasmic reticulum membrane(GO:0005789) |
0.0 | 0.3 | GO:0043196 | varicosity(GO:0043196) |
0.0 | 0.1 | GO:0000127 | transcription factor TFIIIC complex(GO:0000127) |
0.0 | 1.3 | GO:0001669 | acrosomal vesicle(GO:0001669) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.9 | 5.6 | GO:0060698 | endoribonuclease inhibitor activity(GO:0060698) |
0.9 | 3.7 | GO:0005008 | hepatocyte growth factor-activated receptor activity(GO:0005008) |
0.8 | 2.4 | GO:0019776 | Atg8 ligase activity(GO:0019776) |
0.7 | 2.1 | GO:0008401 | retinoic acid 4-hydroxylase activity(GO:0008401) |
0.5 | 4.6 | GO:0004416 | hydroxyacylglutathione hydrolase activity(GO:0004416) |
0.4 | 10.5 | GO:0005351 | sugar:proton symporter activity(GO:0005351) |
0.4 | 1.7 | GO:0004531 | deoxyribonuclease II activity(GO:0004531) |
0.4 | 2.5 | GO:0019238 | cyclohydrolase activity(GO:0019238) |
0.4 | 3.6 | GO:0032564 | dATP binding(GO:0032564) |
0.4 | 1.1 | GO:0019981 | interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981) |
0.4 | 2.2 | GO:0005332 | gamma-aminobutyric acid:sodium symporter activity(GO:0005332) |
0.4 | 1.9 | GO:0004594 | pantothenate kinase activity(GO:0004594) |
0.4 | 1.1 | GO:0046969 | histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969) |
0.3 | 3.0 | GO:0005007 | fibroblast growth factor-activated receptor activity(GO:0005007) |
0.3 | 1.0 | GO:0050508 | glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508) |
0.3 | 1.0 | GO:0004616 | phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616) |
0.3 | 1.1 | GO:0016822 | oxaloacetate decarboxylase activity(GO:0008948) hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823) |
0.3 | 2.7 | GO:0004887 | thyroid hormone receptor activity(GO:0004887) |
0.3 | 1.0 | GO:0032422 | purine-rich negative regulatory element binding(GO:0032422) |
0.2 | 1.2 | GO:0008427 | calcium-dependent protein kinase inhibitor activity(GO:0008427) |
0.2 | 3.1 | GO:0004185 | serine-type carboxypeptidase activity(GO:0004185) |
0.2 | 2.0 | GO:0050291 | sphingosine N-acyltransferase activity(GO:0050291) |
0.2 | 0.6 | GO:0046964 | 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964) |
0.2 | 3.4 | GO:0055106 | ubiquitin-protein transferase regulator activity(GO:0055106) |
0.2 | 0.5 | GO:0030519 | snoRNP binding(GO:0030519) |
0.2 | 0.6 | GO:0016230 | sphingomyelin phosphodiesterase activator activity(GO:0016230) |
0.2 | 0.5 | GO:0001225 | RNA polymerase II transcription coactivator binding(GO:0001225) |
0.1 | 0.5 | GO:0015183 | L-aspartate transmembrane transporter activity(GO:0015183) |
0.1 | 3.4 | GO:0046961 | proton-transporting ATPase activity, rotational mechanism(GO:0046961) |
0.1 | 5.5 | GO:0030332 | cyclin binding(GO:0030332) |
0.1 | 1.7 | GO:0005375 | copper ion transmembrane transporter activity(GO:0005375) |
0.1 | 0.8 | GO:0001226 | RNA polymerase II transcription corepressor binding(GO:0001226) |
0.1 | 2.0 | GO:0001972 | retinoic acid binding(GO:0001972) |
0.1 | 0.8 | GO:0004305 | ethanolamine kinase activity(GO:0004305) |
0.1 | 5.7 | GO:0016790 | thiolester hydrolase activity(GO:0016790) |
0.1 | 0.3 | GO:0051431 | corticotropin-releasing hormone receptor 2 binding(GO:0051431) |
0.1 | 1.0 | GO:0004861 | cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861) |
0.1 | 1.1 | GO:0004983 | neuropeptide Y receptor activity(GO:0004983) |
0.1 | 1.7 | GO:0050811 | GABA receptor binding(GO:0050811) |
0.1 | 2.6 | GO:0034185 | apolipoprotein binding(GO:0034185) |
0.1 | 0.4 | GO:0004045 | aminoacyl-tRNA hydrolase activity(GO:0004045) |
0.1 | 0.5 | GO:0070579 | methylcytosine dioxygenase activity(GO:0070579) |
0.1 | 1.1 | GO:0097109 | neuroligin family protein binding(GO:0097109) |
0.1 | 2.2 | GO:0004697 | protein kinase C activity(GO:0004697) |
0.1 | 1.6 | GO:0008510 | sodium:bicarbonate symporter activity(GO:0008510) |
0.1 | 0.4 | GO:0004563 | beta-N-acetylhexosaminidase activity(GO:0004563) |
0.1 | 2.2 | GO:0070064 | proline-rich region binding(GO:0070064) |
0.1 | 0.7 | GO:0004331 | 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331) |
0.1 | 0.5 | GO:0038132 | neuregulin binding(GO:0038132) |
0.1 | 4.1 | GO:0008138 | protein tyrosine/serine/threonine phosphatase activity(GO:0008138) |
0.1 | 1.2 | GO:0015643 | toxic substance binding(GO:0015643) |
0.1 | 0.9 | GO:0015929 | hexosaminidase activity(GO:0015929) |
0.1 | 1.3 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
0.1 | 0.9 | GO:0005068 | transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068) |
0.1 | 0.9 | GO:0008353 | RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353) |
0.1 | 0.4 | GO:0044729 | hemi-methylated DNA-binding(GO:0044729) |
0.0 | 0.6 | GO:0045236 | CXCR chemokine receptor binding(GO:0045236) |
0.0 | 5.0 | GO:0043130 | ubiquitin binding(GO:0043130) |
0.0 | 0.9 | GO:0034237 | protein kinase A regulatory subunit binding(GO:0034237) |
0.0 | 0.8 | GO:0008327 | methyl-CpG binding(GO:0008327) |
0.0 | 4.7 | GO:0008565 | protein transporter activity(GO:0008565) |
0.0 | 1.6 | GO:0050681 | androgen receptor binding(GO:0050681) |
0.0 | 0.2 | GO:0015272 | ATP-activated inward rectifier potassium channel activity(GO:0015272) |
0.0 | 3.1 | GO:0032947 | protein complex scaffold(GO:0032947) |
0.0 | 0.3 | GO:0051525 | NFAT protein binding(GO:0051525) |
0.0 | 0.1 | GO:0001002 | polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003) |
0.0 | 0.8 | GO:0046966 | thyroid hormone receptor binding(GO:0046966) |
0.0 | 1.8 | GO:0098531 | RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531) |
0.0 | 1.4 | GO:0004177 | aminopeptidase activity(GO:0004177) |
0.0 | 0.2 | GO:0030550 | acetylcholine receptor inhibitor activity(GO:0030550) |
0.0 | 3.3 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
0.0 | 0.4 | GO:0009982 | pseudouridine synthase activity(GO:0009982) |
0.0 | 0.6 | GO:0031005 | filamin binding(GO:0031005) |
0.0 | 0.8 | GO:0051059 | NF-kappaB binding(GO:0051059) |
0.0 | 0.8 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
0.0 | 0.1 | GO:0016774 | phosphotransferase activity, carboxyl group as acceptor(GO:0016774) |
0.0 | 1.5 | GO:0004722 | protein serine/threonine phosphatase activity(GO:0004722) |
0.0 | 0.8 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
0.0 | 0.6 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
0.0 | 1.6 | GO:0019888 | protein phosphatase regulator activity(GO:0019888) |
0.0 | 0.6 | GO:0016881 | acid-amino acid ligase activity(GO:0016881) |
0.0 | 0.7 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
0.0 | 0.1 | GO:1990050 | phosphatidic acid transporter activity(GO:1990050) |
0.0 | 1.4 | GO:0048306 | calcium-dependent protein binding(GO:0048306) |
0.0 | 0.1 | GO:0016971 | flavin-linked sulfhydryl oxidase activity(GO:0016971) |
0.0 | 0.7 | GO:0043027 | cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) |
0.0 | 1.1 | GO:0004843 | thiol-dependent ubiquitin-specific protease activity(GO:0004843) |
0.0 | 0.4 | GO:0051537 | 2 iron, 2 sulfur cluster binding(GO:0051537) |
0.0 | 0.9 | GO:0005507 | copper ion binding(GO:0005507) |
0.0 | 0.7 | GO:0004712 | protein serine/threonine/tyrosine kinase activity(GO:0004712) |
0.0 | 0.2 | GO:0031434 | mitogen-activated protein kinase kinase binding(GO:0031434) |
0.0 | 1.3 | GO:0008013 | beta-catenin binding(GO:0008013) |
0.0 | 1.0 | GO:0005254 | chloride channel activity(GO:0005254) |
0.0 | 6.5 | GO:0001228 | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 3.5 | ST G ALPHA S PATHWAY | G alpha s Pathway |
0.1 | 3.7 | PID ARF6 PATHWAY | Arf6 signaling events |
0.1 | 2.2 | PID INSULIN GLUCOSE PATHWAY | Insulin-mediated glucose transport |
0.1 | 1.1 | SA REG CASCADE OF CYCLIN EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
0.1 | 5.1 | PID LKB1 PATHWAY | LKB1 signaling events |
0.1 | 1.6 | PID WNT CANONICAL PATHWAY | Canonical Wnt signaling pathway |
0.0 | 0.5 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
0.0 | 3.0 | PID FGF PATHWAY | FGF signaling pathway |
0.0 | 0.9 | PID S1P S1P2 PATHWAY | S1P2 pathway |
0.0 | 2.7 | PID AP1 PATHWAY | AP-1 transcription factor network |
0.0 | 0.8 | PID NFKAPPAB ATYPICAL PATHWAY | Atypical NF-kappaB pathway |
0.0 | 1.2 | PID HIF2PATHWAY | HIF-2-alpha transcription factor network |
0.0 | 1.3 | PID ERBB2 ERBB3 PATHWAY | ErbB2/ErbB3 signaling events |
0.0 | 0.7 | PID NETRIN PATHWAY | Netrin-mediated signaling events |
0.0 | 1.3 | PID P73PATHWAY | p73 transcription factor network |
0.0 | 0.8 | PID HDAC CLASSII PATHWAY | Signaling events mediated by HDAC Class II |
0.0 | 0.7 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 3.9 | REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK | Genes involved in Negative regulation of the PI3K/AKT network |
0.3 | 5.7 | REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
0.2 | 3.0 | REACTOME CALNEXIN CALRETICULIN CYCLE | Genes involved in Calnexin/calreticulin cycle |
0.2 | 2.5 | REACTOME VITAMIN B5 PANTOTHENATE METABOLISM | Genes involved in Vitamin B5 (pantothenate) metabolism |
0.2 | 2.5 | REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION | Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation |
0.2 | 2.0 | REACTOME GLUCURONIDATION | Genes involved in Glucuronidation |
0.2 | 3.0 | REACTOME FGFR2C LIGAND BINDING AND ACTIVATION | Genes involved in FGFR2c ligand binding and activation |
0.1 | 3.3 | REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR | Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor |
0.1 | 1.3 | REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING | Genes involved in Downregulation of ERBB2:ERBB3 signaling |
0.1 | 3.4 | REACTOME INSULIN RECEPTOR RECYCLING | Genes involved in Insulin receptor recycling |
0.1 | 2.2 | REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS | Genes involved in Na+/Cl- dependent neurotransmitter transporters |
0.1 | 2.2 | REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION | Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) |
0.1 | 3.7 | REACTOME SEMA4D IN SEMAPHORIN SIGNALING | Genes involved in Sema4D in semaphorin signaling |
0.1 | 1.2 | REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS | Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors |
0.1 | 1.6 | REACTOME CTNNB1 PHOSPHORYLATION CASCADE | Genes involved in Beta-catenin phosphorylation cascade |
0.1 | 3.2 | REACTOME GLYCOSPHINGOLIPID METABOLISM | Genes involved in Glycosphingolipid metabolism |
0.1 | 2.1 | REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE | Genes involved in Cytochrome P450 - arranged by substrate type |
0.1 | 0.8 | REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL | Genes involved in NF-kB is activated and signals survival |
0.1 | 0.9 | REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL | Genes involved in AKT phosphorylates targets in the cytosol |
0.1 | 2.5 | REACTOME SPHINGOLIPID METABOLISM | Genes involved in Sphingolipid metabolism |
0.0 | 4.5 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
0.0 | 0.8 | REACTOME SYNTHESIS OF PE | Genes involved in Synthesis of PE |
0.0 | 1.7 | REACTOME METAL ION SLC TRANSPORTERS | Genes involved in Metal ion SLC transporters |
0.0 | 0.9 | REACTOME SOS MEDIATED SIGNALLING | Genes involved in SOS-mediated signalling |
0.0 | 0.9 | REACTOME FORMATION OF INCISION COMPLEX IN GG NER | Genes involved in Formation of incision complex in GG-NER |
0.0 | 0.6 | REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS | Genes involved in Synthesis of substrates in N-glycan biosythesis |
0.0 | 1.5 | REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES | Genes involved in Transport of vitamins, nucleosides, and related molecules |
0.0 | 0.2 | REACTOME SIGNALLING TO P38 VIA RIT AND RIN | Genes involved in Signalling to p38 via RIT and RIN |
0.0 | 0.9 | REACTOME G1 PHASE | Genes involved in G1 Phase |
0.0 | 2.1 | REACTOME PROTEIN FOLDING | Genes involved in Protein folding |
0.0 | 0.7 | REACTOME DCC MEDIATED ATTRACTIVE SIGNALING | Genes involved in DCC mediated attractive signaling |
0.0 | 0.7 | REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING | Genes involved in Downregulation of TGF-beta receptor signaling |
0.0 | 0.7 | REACTOME G0 AND EARLY G1 | Genes involved in G0 and Early G1 |
0.0 | 0.8 | REACTOME GLYCOLYSIS | Genes involved in Glycolysis |
0.0 | 0.4 | REACTOME MITOCHONDRIAL TRNA AMINOACYLATION | Genes involved in Mitochondrial tRNA aminoacylation |
0.0 | 2.2 | REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION | Genes involved in Factors involved in megakaryocyte development and platelet production |
0.0 | 0.6 | REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
0.0 | 0.5 | REACTOME HS GAG BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
0.0 | 0.8 | REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | Genes involved in NOTCH1 Intracellular Domain Regulates Transcription |