avrg: GSE58827: Dynamics of the Mouse Liver
Gene Symbol | Gene ID | Gene Info |
---|---|---|
Nfe2l2
|
ENSMUSG00000015839.6 | nuclear factor, erythroid derived 2, like 2 |
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Nfe2l2 | mm10_v2_chr2_-_75704535_75704641 | 0.00 | 9.8e-01 | Click! |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.8 | 6.6 | GO:1901750 | leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750) |
0.5 | 1.5 | GO:0071460 | cellular response to cell-matrix adhesion(GO:0071460) |
0.5 | 1.5 | GO:0014809 | regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809) |
0.3 | 0.9 | GO:0090274 | positive regulation of somatostatin secretion(GO:0090274) |
0.3 | 1.1 | GO:0035524 | proline transmembrane transport(GO:0035524) glycine import(GO:0036233) |
0.3 | 0.8 | GO:1904023 | regulation of fermentation(GO:0043465) regulation of bone mineralization involved in bone maturation(GO:1900157) regulation of NAD metabolic process(GO:1902688) regulation of glucose catabolic process to lactate via pyruvate(GO:1904023) |
0.2 | 0.6 | GO:0035585 | calcium-mediated signaling using extracellular calcium source(GO:0035585) |
0.2 | 0.5 | GO:0045079 | negative regulation of chemokine biosynthetic process(GO:0045079) |
0.1 | 0.9 | GO:0007412 | axon target recognition(GO:0007412) |
0.1 | 0.6 | GO:0036414 | protein citrullination(GO:0018101) histone citrullination(GO:0036414) |
0.1 | 1.4 | GO:0030388 | fructose 1,6-bisphosphate metabolic process(GO:0030388) |
0.1 | 0.3 | GO:0036388 | pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) DNA replication preinitiation complex assembly(GO:0071163) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299) |
0.1 | 0.3 | GO:0070649 | formin-nucleated actin cable assembly(GO:0070649) |
0.1 | 1.2 | GO:0006488 | dolichol-linked oligosaccharide biosynthetic process(GO:0006488) |
0.1 | 0.8 | GO:0060050 | positive regulation of protein glycosylation(GO:0060050) |
0.1 | 0.3 | GO:0061153 | negative regulation of interleukin-13 production(GO:0032696) trachea submucosa development(GO:0061152) trachea gland development(GO:0061153) odontoblast differentiation(GO:0071895) regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899) |
0.1 | 0.2 | GO:0002344 | peripheral B cell selection(GO:0002343) B cell affinity maturation(GO:0002344) |
0.1 | 0.2 | GO:0072034 | renal vesicle induction(GO:0072034) |
0.1 | 0.6 | GO:0009137 | purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181) |
0.1 | 0.7 | GO:2000580 | positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582) |
0.1 | 0.9 | GO:0010881 | regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion(GO:0010881) |
0.1 | 2.6 | GO:0007026 | negative regulation of microtubule depolymerization(GO:0007026) |
0.1 | 0.3 | GO:0061086 | negative regulation of histone H3-K27 methylation(GO:0061086) |
0.1 | 0.5 | GO:0038031 | non-canonical Wnt signaling pathway via MAPK cascade(GO:0038030) non-canonical Wnt signaling pathway via JNK cascade(GO:0038031) |
0.1 | 0.2 | GO:0033387 | putrescine biosynthetic process from ornithine(GO:0033387) |
0.0 | 0.1 | GO:0070488 | neutrophil aggregation(GO:0070488) |
0.0 | 0.3 | GO:0006108 | malate metabolic process(GO:0006108) regulation of NADP metabolic process(GO:1902031) |
0.0 | 0.4 | GO:0006729 | tetrahydrobiopterin biosynthetic process(GO:0006729) |
0.0 | 0.6 | GO:0002862 | negative regulation of inflammatory response to antigenic stimulus(GO:0002862) |
0.0 | 0.1 | GO:0060821 | inactivation of X chromosome by DNA methylation(GO:0060821) |
0.0 | 0.2 | GO:0060830 | ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830) |
0.0 | 0.2 | GO:0000454 | snoRNA guided rRNA pseudouridine synthesis(GO:0000454) |
0.0 | 0.2 | GO:0001550 | ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) |
0.0 | 0.2 | GO:0072138 | mesenchymal cell proliferation involved in ureteric bud development(GO:0072138) |
0.0 | 0.1 | GO:0021933 | radial glia guided migration of cerebellar granule cell(GO:0021933) |
0.0 | 0.4 | GO:0070389 | chaperone cofactor-dependent protein refolding(GO:0070389) |
0.0 | 0.7 | GO:0032825 | positive regulation of natural killer cell differentiation(GO:0032825) |
0.0 | 0.1 | GO:0006624 | vacuolar protein processing(GO:0006624) |
0.0 | 0.2 | GO:0071543 | diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911) |
0.0 | 0.4 | GO:0043248 | proteasome assembly(GO:0043248) |
0.0 | 0.1 | GO:0038128 | ERBB2 signaling pathway(GO:0038128) |
0.0 | 0.7 | GO:0071450 | cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) |
0.0 | 0.1 | GO:0046826 | negative regulation of protein export from nucleus(GO:0046826) |
0.0 | 0.5 | GO:0060707 | trophoblast giant cell differentiation(GO:0060707) |
0.0 | 1.0 | GO:0003009 | skeletal muscle contraction(GO:0003009) |
0.0 | 0.2 | GO:0070236 | negative regulation of activation-induced cell death of T cells(GO:0070236) |
0.0 | 0.3 | GO:0051152 | positive regulation of smooth muscle cell differentiation(GO:0051152) |
0.0 | 0.2 | GO:0044331 | cell-cell adhesion mediated by cadherin(GO:0044331) |
0.0 | 0.2 | GO:0010992 | ubiquitin homeostasis(GO:0010992) |
0.0 | 0.1 | GO:0042148 | strand invasion(GO:0042148) |
0.0 | 0.1 | GO:0010968 | regulation of microtubule nucleation(GO:0010968) |
0.0 | 0.3 | GO:0048671 | negative regulation of collateral sprouting(GO:0048671) |
0.0 | 0.3 | GO:0060363 | cranial suture morphogenesis(GO:0060363) |
0.0 | 0.6 | GO:1903963 | arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963) |
0.0 | 0.1 | GO:0051661 | maintenance of centrosome location(GO:0051661) |
0.0 | 0.1 | GO:0070294 | renal sodium ion absorption(GO:0070294) regulation of inward rectifier potassium channel activity(GO:1901979) |
0.0 | 0.2 | GO:0033234 | negative regulation of protein sumoylation(GO:0033234) |
0.0 | 0.1 | GO:0035617 | stress granule disassembly(GO:0035617) |
0.0 | 0.0 | GO:0006222 | UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049) |
0.0 | 0.1 | GO:0034769 | basement membrane disassembly(GO:0034769) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 1.5 | GO:0033018 | sarcoplasmic reticulum lumen(GO:0033018) |
0.2 | 0.7 | GO:1990257 | piccolo-bassoon transport vesicle(GO:1990257) |
0.1 | 0.6 | GO:0031095 | platelet dense tubular network membrane(GO:0031095) |
0.1 | 0.3 | GO:0005656 | nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387) |
0.1 | 1.4 | GO:0035686 | sperm fibrous sheath(GO:0035686) |
0.1 | 1.2 | GO:0005861 | troponin complex(GO:0005861) |
0.0 | 0.2 | GO:0090661 | box H/ACA telomerase RNP complex(GO:0090661) |
0.0 | 0.1 | GO:0097057 | TRAF2-GSTP1 complex(GO:0097057) |
0.0 | 0.2 | GO:0032437 | cuticular plate(GO:0032437) |
0.0 | 0.3 | GO:0032937 | SREBP-SCAP-Insig complex(GO:0032937) |
0.0 | 0.3 | GO:1990907 | beta-catenin-TCF complex(GO:1990907) |
0.0 | 0.3 | GO:0008541 | proteasome regulatory particle, lid subcomplex(GO:0008541) |
0.0 | 0.7 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
0.0 | 0.8 | GO:0005865 | striated muscle thin filament(GO:0005865) |
0.0 | 0.6 | GO:0005605 | basal lamina(GO:0005605) |
0.0 | 0.1 | GO:1990462 | omegasome(GO:1990462) |
0.0 | 0.4 | GO:0005697 | telomerase holoenzyme complex(GO:0005697) |
0.0 | 0.3 | GO:0031229 | integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) |
0.0 | 0.2 | GO:0031931 | TORC1 complex(GO:0031931) |
0.0 | 0.1 | GO:0005896 | interleukin-6 receptor complex(GO:0005896) |
0.0 | 0.2 | GO:0019773 | proteasome core complex, alpha-subunit complex(GO:0019773) |
0.0 | 0.1 | GO:0000235 | astral microtubule(GO:0000235) |
0.0 | 2.3 | GO:0005875 | microtubule associated complex(GO:0005875) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 6.6 | GO:0036374 | glutathione hydrolase activity(GO:0036374) |
0.4 | 1.1 | GO:0005302 | L-tyrosine transmembrane transporter activity(GO:0005302) |
0.3 | 1.7 | GO:0018685 | alkane 1-monooxygenase activity(GO:0018685) |
0.2 | 0.9 | GO:0031694 | alpha-2A adrenergic receptor binding(GO:0031694) |
0.2 | 1.4 | GO:0004332 | fructose-bisphosphate aldolase activity(GO:0004332) |
0.1 | 0.4 | GO:0004155 | 6,7-dihydropteridine reductase activity(GO:0004155) |
0.1 | 0.6 | GO:0004668 | protein-arginine deiminase activity(GO:0004668) |
0.1 | 0.3 | GO:0004471 | malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473) |
0.1 | 0.4 | GO:0050220 | prostaglandin-E synthase activity(GO:0050220) |
0.1 | 0.6 | GO:0043262 | adenosine-diphosphatase activity(GO:0043262) |
0.1 | 1.1 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
0.1 | 0.3 | GO:0004784 | superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721) |
0.0 | 0.3 | GO:0030284 | estrogen receptor activity(GO:0030284) |
0.0 | 0.3 | GO:0061629 | RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629) |
0.0 | 1.5 | GO:0001968 | fibronectin binding(GO:0001968) |
0.0 | 0.7 | GO:0045504 | dynein heavy chain binding(GO:0045504) |
0.0 | 0.3 | GO:0035381 | extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381) |
0.0 | 0.7 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
0.0 | 0.9 | GO:0004602 | glutathione peroxidase activity(GO:0004602) |
0.0 | 0.2 | GO:0034513 | box H/ACA snoRNA binding(GO:0034513) |
0.0 | 0.2 | GO:0034432 | endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) |
0.0 | 5.2 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
0.0 | 0.1 | GO:0015272 | ATP-activated inward rectifier potassium channel activity(GO:0015272) |
0.0 | 0.2 | GO:0016018 | cyclosporin A binding(GO:0016018) |
0.0 | 0.1 | GO:0015038 | glutathione disulfide oxidoreductase activity(GO:0015038) |
0.0 | 0.3 | GO:0003688 | DNA replication origin binding(GO:0003688) |
0.0 | 0.5 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
0.0 | 0.1 | GO:0000150 | recombinase activity(GO:0000150) |
0.0 | 0.1 | GO:0047134 | protein-disulfide reductase activity(GO:0047134) |
0.0 | 0.6 | GO:0004623 | phospholipase A2 activity(GO:0004623) |
0.0 | 0.1 | GO:0003886 | DNA (cytosine-5-)-methyltransferase activity(GO:0003886) |
0.0 | 0.1 | GO:0030375 | thyroid hormone receptor coactivator activity(GO:0030375) |
0.0 | 0.2 | GO:0005025 | transforming growth factor beta receptor activity, type I(GO:0005025) |
0.0 | 0.9 | GO:0008395 | steroid hydroxylase activity(GO:0008395) |
0.0 | 2.2 | GO:0002020 | protease binding(GO:0002020) |
0.0 | 1.2 | GO:0048306 | calcium-dependent protein binding(GO:0048306) |
0.0 | 0.1 | GO:0008379 | thioredoxin peroxidase activity(GO:0008379) |
0.0 | 0.3 | GO:0004298 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
0.0 | 0.1 | GO:0016661 | oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661) |
0.0 | 0.1 | GO:0070699 | type II activin receptor binding(GO:0070699) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 1.8 | PID FRA PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
0.0 | 0.9 | PID ALPHA SYNUCLEIN PATHWAY | Alpha-synuclein signaling |
0.0 | 0.5 | PID WNT SIGNALING PATHWAY | Wnt signaling network |
0.0 | 1.4 | PID HIF1 TFPATHWAY | HIF-1-alpha transcription factor network |
0.0 | 0.8 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 6.3 | REACTOME GLUTATHIONE CONJUGATION | Genes involved in Glutathione conjugation |
0.1 | 1.7 | REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX | Genes involved in Degradation of the extracellular matrix |
0.0 | 0.6 | REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL | Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol |
0.0 | 1.4 | REACTOME GLYCOLYSIS | Genes involved in Glycolysis |
0.0 | 0.6 | REACTOME ACYL CHAIN REMODELLING OF PI | Genes involved in Acyl chain remodelling of PI |
0.0 | 1.1 | REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
0.0 | 1.2 | REACTOME STRIATED MUSCLE CONTRACTION | Genes involved in Striated Muscle Contraction |
0.0 | 0.3 | REACTOME IL 6 SIGNALING | Genes involved in Interleukin-6 signaling |
0.0 | 0.3 | REACTOME UNWINDING OF DNA | Genes involved in Unwinding of DNA |