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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for AACACUG

Z-value: 0.74

Motif logo

miRNA associated with seed AACACUG

NamemiRBASE accession
MIMAT0000153
MIMAT0000519

Activity profile of AACACUG motif

Sorted Z-values of AACACUG motif

Network of associatons between targets according to the STRING database.

First level regulatory network of AACACUG

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0061552 vestibulocochlear nerve structural organization(GO:0021649) cell migration involved in vasculogenesis(GO:0035441) neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190) ganglion morphogenesis(GO:0061552) dorsal root ganglion morphogenesis(GO:1904835)
0.4 1.2 GO:1902809 regulation of skeletal muscle fiber differentiation(GO:1902809)
0.4 1.4 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.3 1.0 GO:0007529 establishment of synaptic specificity at neuromuscular junction(GO:0007529)
0.3 1.4 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.3 1.0 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.3 0.8 GO:0071579 regulation of zinc ion transport(GO:0071579)
0.3 0.8 GO:0061144 alveolar secondary septum development(GO:0061144)
0.2 0.9 GO:0090126 protein complex assembly involved in synapse maturation(GO:0090126)
0.2 0.7 GO:0045013 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.2 0.6 GO:1905051 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
0.2 0.6 GO:0036446 myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760)
0.2 0.8 GO:0021698 cerebellar cortex structural organization(GO:0021698)
0.2 0.8 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.2 0.5 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.2 0.5 GO:0034334 adherens junction maintenance(GO:0034334)
0.2 0.5 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.2 0.5 GO:0035621 ER to Golgi ceramide transport(GO:0035621)
0.2 0.3 GO:0009826 unidimensional cell growth(GO:0009826)
0.1 0.4 GO:0042339 keratan sulfate metabolic process(GO:0042339)
0.1 0.4 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
0.1 0.4 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.1 0.4 GO:2000812 regulation of barbed-end actin filament capping(GO:2000812)
0.1 0.8 GO:0002084 protein depalmitoylation(GO:0002084) negative regulation of Golgi to plasma membrane protein transport(GO:0042997) negative regulation of establishment of protein localization to plasma membrane(GO:0090005) macromolecule depalmitoylation(GO:0098734)
0.1 1.2 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.1 0.4 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.1 0.5 GO:0006742 NADP catabolic process(GO:0006742)
0.1 0.4 GO:1905223 epicardium morphogenesis(GO:1905223)
0.1 0.7 GO:0051891 positive regulation of cardioblast differentiation(GO:0051891)
0.1 0.5 GO:1902966 regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
0.1 0.2 GO:0035973 aggrephagy(GO:0035973)
0.1 1.5 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.1 0.8 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.1 0.3 GO:0010040 response to iron(II) ion(GO:0010040)
0.1 0.9 GO:0075044 autophagy of host cells involved in interaction with symbiont(GO:0075044) autophagy involved in symbiotic interaction(GO:0075071)
0.1 0.4 GO:0046881 positive regulation of follicle-stimulating hormone secretion(GO:0046881)
0.1 0.3 GO:1903279 regulation of calcium:sodium antiporter activity(GO:1903279)
0.1 0.3 GO:1901475 pyruvate transmembrane transport(GO:1901475)
0.1 0.5 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.1 0.3 GO:0009957 epidermal cell fate specification(GO:0009957)
0.1 0.6 GO:0051612 negative regulation of neurotransmitter uptake(GO:0051581) negative regulation of serotonin uptake(GO:0051612)
0.1 0.3 GO:1903912 negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912)
0.1 0.6 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.1 0.6 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1 0.5 GO:0034197 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.1 0.4 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.1 0.8 GO:0008063 Toll signaling pathway(GO:0008063)
0.1 0.4 GO:1900170 prolactin signaling pathway(GO:0038161) negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.1 0.4 GO:0070459 prolactin secretion(GO:0070459) regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.1 0.7 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.1 0.3 GO:0021764 amygdala development(GO:0021764)
0.1 0.3 GO:0097343 ripoptosome assembly(GO:0097343) ripoptosome assembly involved in necroptotic process(GO:1901026)
0.1 0.3 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.1 0.6 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.1 0.7 GO:0072307 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.1 0.2 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.1 0.2 GO:2001016 positive regulation of skeletal muscle cell differentiation(GO:2001016)
0.1 0.4 GO:0016266 O-glycan processing(GO:0016266)
0.1 0.2 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
0.1 0.3 GO:0061502 early endosome to recycling endosome transport(GO:0061502)
0.1 0.4 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.1 0.2 GO:0030202 heparin metabolic process(GO:0030202)
0.1 0.4 GO:1904016 response to Thyroglobulin triiodothyronine(GO:1904016) cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.1 0.2 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.0 0.2 GO:0060355 positive regulation of cell adhesion molecule production(GO:0060355)
0.0 0.3 GO:0098963 dendritic transport of ribonucleoprotein complex(GO:0098961) dendritic transport of messenger ribonucleoprotein complex(GO:0098963) anterograde dendritic transport of messenger ribonucleoprotein complex(GO:0098964)
0.0 0.7 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 0.5 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.0 0.1 GO:1904580 regulation of polynucleotide adenylyltransferase activity(GO:1904245) regulation of intracellular mRNA localization(GO:1904580)
0.0 0.1 GO:0071707 immunoglobulin heavy chain V-D-J recombination(GO:0071707)
0.0 0.4 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.3 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.0 0.1 GO:0052055 modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.0 0.3 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.4 GO:0060613 fat pad development(GO:0060613)
0.0 0.7 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
0.0 0.2 GO:0090168 Golgi reassembly(GO:0090168)
0.0 0.1 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 1.0 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.4 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.2 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.6 GO:0010225 response to UV-C(GO:0010225)
0.0 0.3 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.0 0.2 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.2 GO:0036089 cleavage furrow formation(GO:0036089)
0.0 0.1 GO:0048209 regulation of vesicle targeting, to, from or within Golgi(GO:0048209)
0.0 0.1 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.0 0.5 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.7 GO:0034453 microtubule anchoring(GO:0034453)
0.0 0.1 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.0 0.1 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.2 GO:0044791 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.0 0.1 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.0 0.2 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.0 0.7 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.3 GO:0009435 NAD biosynthetic process(GO:0009435)
0.0 0.1 GO:1904690 regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
0.0 0.6 GO:0035641 locomotory exploration behavior(GO:0035641)
0.0 0.3 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.2 GO:0042136 neurotransmitter biosynthetic process(GO:0042136)
0.0 0.3 GO:0035878 nail development(GO:0035878)
0.0 0.2 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.0 0.1 GO:0021594 rhombomere formation(GO:0021594) rhombomere 3 formation(GO:0021660) rhombomere 5 morphogenesis(GO:0021664) rhombomere 5 formation(GO:0021666)
0.0 0.3 GO:0036315 cellular response to sterol(GO:0036315)
0.0 0.5 GO:0044406 adhesion of symbiont to host(GO:0044406)
0.0 0.7 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 0.2 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.5 GO:0010884 positive regulation of lipid storage(GO:0010884)
0.0 0.2 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.1 GO:0035552 oxidative single-stranded DNA demethylation(GO:0035552) oxidative single-stranded RNA demethylation(GO:0035553)
0.0 0.1 GO:0070672 response to interleukin-15(GO:0070672)
0.0 0.2 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.0 0.0 GO:0072194 kidney smooth muscle tissue development(GO:0072194)
0.0 0.2 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.5 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0 0.8 GO:0033120 positive regulation of RNA splicing(GO:0033120)
0.0 0.2 GO:0033129 positive regulation of histone phosphorylation(GO:0033129)
0.0 0.9 GO:0051438 regulation of ubiquitin-protein transferase activity(GO:0051438)
0.0 0.3 GO:0071625 vocalization behavior(GO:0071625)
0.0 0.0 GO:0002270 plasmacytoid dendritic cell activation(GO:0002270)
0.0 0.1 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.2 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.2 GO:0042297 vocal learning(GO:0042297) imitative learning(GO:0098596) observational learning(GO:0098597)
0.0 0.9 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.4 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.2 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 0.1 GO:0033227 dsRNA transport(GO:0033227)
0.0 0.2 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.7 GO:1901998 toxin transport(GO:1901998)
0.0 0.1 GO:0030035 microspike assembly(GO:0030035)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.1 GO:0006265 DNA topological change(GO:0006265)
0.0 0.2 GO:0090209 negative regulation of triglyceride metabolic process(GO:0090209)
0.0 0.3 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.0 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.0 0.1 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
0.0 0.1 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.0 0.2 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.0 0.1 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.3 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.2 GO:0021860 pyramidal neuron development(GO:0021860)
0.0 0.1 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.0 0.5 GO:0043171 peptide catabolic process(GO:0043171)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.3 GO:0097443 sorting endosome(GO:0097443)
0.1 0.4 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.1 0.4 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.1 0.5 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.1 0.4 GO:0005940 septin ring(GO:0005940)
0.1 0.4 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.1 0.7 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 0.9 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 0.2 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.1 0.9 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.1 0.4 GO:0008290 F-actin capping protein complex(GO:0008290)
0.1 0.7 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 0.3 GO:0036449 microtubule minus-end(GO:0036449)
0.1 0.7 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 0.4 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 1.9 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.7 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.2 GO:0032280 symmetric synapse(GO:0032280)
0.0 0.3 GO:0071203 WASH complex(GO:0071203)
0.0 0.5 GO:0020005 symbiont-containing vacuole membrane(GO:0020005)
0.0 0.3 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.2 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.0 0.8 GO:0000145 exocyst(GO:0000145)
0.0 0.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.5 GO:0051286 cell tip(GO:0051286)
0.0 0.4 GO:0032156 septin cytoskeleton(GO:0032156)
0.0 0.0 GO:0002142 stereocilia ankle link complex(GO:0002142)
0.0 0.1 GO:0032437 cuticular plate(GO:0032437)
0.0 0.2 GO:0005827 polar microtubule(GO:0005827)
0.0 1.1 GO:0031902 late endosome membrane(GO:0031902)
0.0 0.3 GO:0070852 cell body fiber(GO:0070852)
0.0 0.3 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.2 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.1 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.0 0.5 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.3 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.2 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 0.1 GO:0016939 kinesin II complex(GO:0016939)
0.0 0.1 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.0 0.1 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 0.1 GO:0001651 dense fibrillar component(GO:0001651)
0.0 0.5 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.0 0.1 GO:0070578 RISC-loading complex(GO:0070578)
0.0 1.0 GO:0032420 stereocilium(GO:0032420)
0.0 0.7 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 1.2 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.1 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.5 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.7 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 1.1 GO:0005643 nuclear pore(GO:0005643)
0.0 0.2 GO:0033391 chromatoid body(GO:0033391)
0.0 0.1 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.5 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.1 GO:0098536 deuterosome(GO:0098536)
0.0 0.8 GO:0005902 microvillus(GO:0005902)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.3 1.0 GO:0008940 nitrate reductase activity(GO:0008940)
0.3 1.3 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.2 0.8 GO:0035276 ethanol binding(GO:0035276)
0.2 1.5 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.2 1.5 GO:0070324 thyroid hormone binding(GO:0070324)
0.1 0.4 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.1 0.6 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.1 0.3 GO:0008158 smoothened binding(GO:0005119) hedgehog receptor activity(GO:0008158)
0.1 0.5 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 0.6 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.1 0.4 GO:0048408 epidermal growth factor-activated receptor activity(GO:0005006) epidermal growth factor binding(GO:0048408)
0.1 0.3 GO:0030350 iron-responsive element binding(GO:0030350) 3 iron, 4 sulfur cluster binding(GO:0051538)
0.1 0.3 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.1 0.2 GO:0019153 protein-disulfide reductase (glutathione) activity(GO:0019153)
0.1 0.8 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.5 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.1 0.5 GO:0097001 ceramide binding(GO:0097001)
0.1 0.7 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 0.9 GO:0097109 neuroligin family protein binding(GO:0097109)
0.1 0.4 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.1 0.3 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 0.6 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.1 0.2 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1 0.8 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 0.8 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.1 0.4 GO:0033142 progesterone receptor binding(GO:0033142)
0.1 0.4 GO:0008312 signal recognition particle binding(GO:0005047) 7S RNA binding(GO:0008312)
0.1 0.2 GO:0036033 mediator complex binding(GO:0036033)
0.1 0.2 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 0.2 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.1 0.4 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.1 0.2 GO:0031208 POZ domain binding(GO:0031208)
0.1 0.3 GO:0008142 oxysterol binding(GO:0008142)
0.1 0.2 GO:0015229 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.0 0.5 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.7 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.4 GO:0017002 activin-activated receptor activity(GO:0017002)
0.0 1.0 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.2 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.4 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 1.0 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.1 GO:0035500 MH2 domain binding(GO:0035500)
0.0 0.4 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.4 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.0 0.4 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.3 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.2 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.2 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.2 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.3 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 1.6 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.2 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.8 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.1 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 1.0 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.7 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.5 GO:0017166 vinculin binding(GO:0017166)
0.0 0.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.4 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.2 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.7 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.2 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.3 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.1 GO:0097100 supercoiled DNA binding(GO:0097100)
0.0 0.1 GO:0051747 cytosine C-5 DNA demethylase activity(GO:0051747)
0.0 0.6 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 1.0 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.4 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.3 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.5 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.4 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.8 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.4 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.4 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.1 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 0.5 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.0 GO:0000401 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)
0.0 2.0 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.1 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.9 GO:0019003 GDP binding(GO:0019003)
0.0 0.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.0 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.0 1.1 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 1.0 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.2 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.1 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.2 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.8 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.4 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 1.7 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.3 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 1.3 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.4 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 1.5 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.4 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.3 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.4 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.2 PID ATM PATHWAY ATM pathway
0.0 0.8 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.2 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.7 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.4 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.3 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.2 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.3 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.4 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.7 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.4 PID SHP2 PATHWAY SHP2 signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 0.8 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.5 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 1.2 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.7 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.3 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 1.0 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.4 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.0 1.5 REACTOME DAG AND IP3 SIGNALING Genes involved in DAG and IP3 signaling
0.0 0.7 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 1.8 REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
0.0 0.3 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.5 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.8 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 2.5 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.8 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.4 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.4 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.8 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.4 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.6 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.6 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.4 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.4 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.4 REACTOME SIGNALING BY NOTCH1 Genes involved in Signaling by NOTCH1
0.0 0.5 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.2 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.4 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.2 REACTOME LIPOPROTEIN METABOLISM Genes involved in Lipoprotein metabolism
0.0 1.1 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.4 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.6 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 1.1 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.1 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.1 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.3 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.2 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.1 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway