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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Nr1h4

Z-value: 2.70

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Transcription factors associated with Nr1h4

Gene Symbol Gene ID Gene Info
ENSMUSG00000047638.9 nuclear receptor subfamily 1, group H, member 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nr1h4mm10_v2_chr10_-_89506631_895066580.889.1e-13Click!

Activity profile of Nr1h4 motif

Sorted Z-values of Nr1h4 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Nr1h4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 13.3 GO:0071718 sodium-independent icosanoid transport(GO:0071718)
2.9 11.6 GO:0010901 regulation of very-low-density lipoprotein particle remodeling(GO:0010901)
2.3 14.0 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
2.2 30.9 GO:0006751 glutathione catabolic process(GO:0006751)
2.2 10.8 GO:0015886 heme transport(GO:0015886)
1.9 17.1 GO:0060050 positive regulation of protein glycosylation(GO:0060050)
1.7 10.0 GO:0046618 drug export(GO:0046618)
1.6 6.6 GO:0048807 female genitalia morphogenesis(GO:0048807)
1.3 8.9 GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
1.2 3.5 GO:1990166 protein localization to site of double-strand break(GO:1990166)
1.1 3.4 GO:0006507 GPI anchor release(GO:0006507)
1.1 5.5 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
1.1 5.3 GO:0032827 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253) negative regulation of natural killer cell differentiation(GO:0032824) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827)
1.0 2.9 GO:1902071 positive regulation of cellular response to hypoxia(GO:1900039) regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
1.0 2.9 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534) positive regulation of MDA-5 signaling pathway(GO:1900245)
0.9 3.6 GO:0006742 NADP catabolic process(GO:0006742)
0.8 5.1 GO:0015889 cobalamin transport(GO:0015889)
0.8 4.7 GO:1903275 positive regulation of sodium ion export(GO:1903275) positive regulation of sodium ion export from cell(GO:1903278)
0.7 9.7 GO:0006857 oligopeptide transport(GO:0006857)
0.7 9.2 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.6 2.4 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.6 6.5 GO:0061370 testosterone biosynthetic process(GO:0061370)
0.6 5.9 GO:0015879 carnitine transport(GO:0015879)
0.6 1.7 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.6 9.2 GO:0036158 outer dynein arm assembly(GO:0036158)
0.5 3.1 GO:0060523 Sertoli cell proliferation(GO:0060011) prostate epithelial cord elongation(GO:0060523)
0.5 4.1 GO:0046874 quinolinate metabolic process(GO:0046874)
0.5 1.5 GO:0071929 alpha-tubulin acetylation(GO:0071929)
0.5 4.7 GO:1900194 receptor guanylyl cyclase signaling pathway(GO:0007168) negative regulation of oocyte maturation(GO:1900194)
0.5 1.9 GO:0007525 somatic muscle development(GO:0007525)
0.5 3.3 GO:0036438 maintenance of lens transparency(GO:0036438)
0.5 1.8 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
0.5 1.4 GO:1903903 regulation of establishment of T cell polarity(GO:1903903)
0.4 4.4 GO:0060763 mammary duct terminal end bud growth(GO:0060763)
0.4 2.0 GO:0060296 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108) regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.4 4.1 GO:0018298 protein-chromophore linkage(GO:0018298)
0.4 1.1 GO:0006114 glycerol biosynthetic process(GO:0006114)
0.4 5.3 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.3 1.0 GO:0070375 ERK5 cascade(GO:0070375)
0.3 1.7 GO:0048597 post-embryonic eye morphogenesis(GO:0048050) post-embryonic camera-type eye morphogenesis(GO:0048597)
0.3 1.3 GO:0035524 proline transmembrane transport(GO:0035524)
0.3 1.0 GO:0048850 hypophysis morphogenesis(GO:0048850)
0.2 3.2 GO:0070995 NADPH oxidation(GO:0070995)
0.2 0.9 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.2 1.5 GO:0042737 drug catabolic process(GO:0042737)
0.2 7.0 GO:0071625 vocalization behavior(GO:0071625)
0.2 1.5 GO:0038030 non-canonical Wnt signaling pathway via MAPK cascade(GO:0038030) non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.2 0.8 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.2 2.7 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.2 13.4 GO:0019369 arachidonic acid metabolic process(GO:0019369)
0.2 2.8 GO:2000400 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.2 15.4 GO:0070206 protein trimerization(GO:0070206)
0.2 9.9 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.2 0.5 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.2 2.1 GO:0048680 positive regulation of axon regeneration(GO:0048680)
0.2 0.8 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.2 1.2 GO:0007021 tubulin complex assembly(GO:0007021)
0.2 1.2 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
0.2 1.4 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.2 1.9 GO:0034141 positive regulation of toll-like receptor 3 signaling pathway(GO:0034141)
0.2 5.6 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.2 0.9 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.2 0.8 GO:0034628 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.1 1.4 GO:2000609 regulation of thyroid hormone generation(GO:2000609)
0.1 2.8 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.1 11.2 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.1 0.8 GO:0015871 choline transport(GO:0015871)
0.1 3.3 GO:0006084 acetyl-CoA metabolic process(GO:0006084)
0.1 0.5 GO:2001205 negative regulation of osteoclast development(GO:2001205)
0.1 1.7 GO:0006662 glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.1 5.9 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.1 4.3 GO:0060612 adipose tissue development(GO:0060612)
0.1 0.3 GO:2001025 positive regulation of response to drug(GO:2001025)
0.1 0.2 GO:0001788 antibody-dependent cellular cytotoxicity(GO:0001788)
0.1 0.6 GO:0031639 plasminogen activation(GO:0031639)
0.1 0.4 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.1 0.4 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.1 0.3 GO:0018343 protein farnesylation(GO:0018343)
0.1 1.7 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.1 2.4 GO:0050919 negative chemotaxis(GO:0050919)
0.1 0.7 GO:1900037 regulation of cellular response to hypoxia(GO:1900037)
0.0 0.9 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 1.0 GO:0006491 N-glycan processing(GO:0006491)
0.0 2.0 GO:0009268 response to pH(GO:0009268)
0.0 0.4 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 2.9 GO:0022904 respiratory electron transport chain(GO:0022904)
0.0 0.1 GO:0060075 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935) regulation of resting membrane potential(GO:0060075)
0.0 2.1 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.0 2.1 GO:0006096 glycolytic process(GO:0006096)
0.0 0.6 GO:0006903 vesicle targeting(GO:0006903)
0.0 3.7 GO:0007596 blood coagulation(GO:0007596)
0.0 1.8 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 1.1 GO:0019228 neuronal action potential(GO:0019228)
0.0 0.8 GO:0006505 GPI anchor metabolic process(GO:0006505)
0.0 1.7 GO:0043627 response to estrogen(GO:0043627)
0.0 1.4 GO:0044042 glycogen metabolic process(GO:0005977) cellular glucan metabolic process(GO:0006073) glucan metabolic process(GO:0044042)
0.0 0.5 GO:0030261 chromosome condensation(GO:0030261)
0.0 1.1 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0 2.9 GO:0006470 protein dephosphorylation(GO:0006470)
0.0 0.1 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.0 0.0 GO:0006657 CDP-choline pathway(GO:0006657)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 7.0 GO:0097513 myosin II filament(GO:0097513)
0.8 10.0 GO:0046581 intercellular canaliculus(GO:0046581)
0.5 11.6 GO:0042627 chylomicron(GO:0042627)
0.4 3.1 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.4 6.5 GO:0070852 cell body fiber(GO:0070852)
0.3 3.4 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.3 2.0 GO:0033269 internode region of axon(GO:0033269)
0.2 2.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.2 4.8 GO:0031091 platelet alpha granule(GO:0031091)
0.2 35.3 GO:0072562 blood microparticle(GO:0072562)
0.2 1.4 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.2 4.7 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.2 2.0 GO:0034464 BBSome(GO:0034464)
0.2 8.9 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.2 13.3 GO:0009925 basal plasma membrane(GO:0009925)
0.2 14.0 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.2 1.5 GO:0097427 microtubule bundle(GO:0097427)
0.2 5.9 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.2 3.1 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.2 0.8 GO:0070876 SOSS complex(GO:0070876)
0.2 1.4 GO:0016600 flotillin complex(GO:0016600)
0.1 9.3 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 2.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 0.6 GO:0097441 basilar dendrite(GO:0097441)
0.1 3.5 GO:0035861 site of double-strand break(GO:0035861)
0.1 1.2 GO:0097512 cardiac myofibril(GO:0097512)
0.1 0.8 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.1 9.2 GO:0036064 ciliary basal body(GO:0036064)
0.1 4.3 GO:0014704 intercalated disc(GO:0014704)
0.0 0.6 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 9.8 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.2 GO:0031501 mannosyltransferase complex(GO:0031501)
0.0 6.5 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.6 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 1.7 GO:0005876 spindle microtubule(GO:0005876)
0.0 1.4 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.3 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.5 GO:0005921 gap junction(GO:0005921)
0.0 1.2 GO:0000786 nucleosome(GO:0000786)
0.0 9.2 GO:0005740 mitochondrial envelope(GO:0005740)
0.0 0.5 GO:0030173 integral component of Golgi membrane(GO:0030173)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 8.9 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
2.7 10.8 GO:0015232 heme transporter activity(GO:0015232)
2.6 30.9 GO:0036374 glutathione hydrolase activity(GO:0036374)
2.3 14.0 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
1.6 6.5 GO:0003865 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) cholestenone 5-alpha-reductase activity(GO:0047751)
1.6 33.0 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
1.4 11.6 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
1.1 5.3 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745) peptidoglycan receptor activity(GO:0016019)
1.0 3.1 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
1.0 5.9 GO:0015226 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.9 4.7 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.8 3.3 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.7 3.3 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.6 2.8 GO:0034235 GPI anchor binding(GO:0034235)
0.6 5.1 GO:0031419 cobalamin binding(GO:0031419)
0.6 1.7 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.5 6.6 GO:0016918 retinal binding(GO:0016918)
0.5 4.1 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.5 4.7 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.4 11.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.4 3.5 GO:0003909 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.4 3.4 GO:0004630 phospholipase D activity(GO:0004630)
0.3 7.0 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.3 1.7 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.3 1.1 GO:0008967 phosphoglycolate phosphatase activity(GO:0008967)
0.3 1.1 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.2 1.5 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.2 1.7 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.2 7.5 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.2 2.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.2 13.4 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.2 1.4 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.2 4.1 GO:0019825 oxygen binding(GO:0019825)
0.2 0.5 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.2 2.0 GO:0034452 dynactin binding(GO:0034452)
0.2 1.0 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.2 29.0 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)
0.2 0.8 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.1 2.8 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1 4.6 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.1 3.1 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 3.6 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.1 2.7 GO:0035497 cAMP response element binding(GO:0035497)
0.1 1.3 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.1 0.8 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.1 2.1 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.1 2.0 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 1.4 GO:0048038 quinone binding(GO:0048038)
0.1 6.2 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.1 4.7 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 5.3 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.1 15.6 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 16.5 GO:0004866 endopeptidase inhibitor activity(GO:0004866)
0.1 0.5 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.1 1.6 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.6 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 1.1 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 1.2 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.2 GO:0019770 IgG receptor activity(GO:0019770)
0.0 2.1 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.4 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 1.8 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 1.7 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 1.2 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 2.6 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.1 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 1.2 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 1.4 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 1.8 GO:0043621 protein self-association(GO:0043621)
0.0 2.9 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.9 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 2.0 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.6 GO:0017171 serine-type peptidase activity(GO:0008236) serine hydrolase activity(GO:0017171)
0.0 1.7 GO:0008013 beta-catenin binding(GO:0008013)
0.0 1.0 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.8 GO:0043022 ribosome binding(GO:0043022)
0.0 1.5 GO:0030165 PDZ domain binding(GO:0030165)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 16.6 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.4 9.9 ST G ALPHA S PATHWAY G alpha s Pathway
0.2 35.7 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 1.7 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.1 3.4 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 4.4 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.1 3.1 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 1.5 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 1.0 ST GA12 PATHWAY G alpha 12 Pathway
0.0 6.8 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.2 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 1.4 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 1.7 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 1.7 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 13.3 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
1.0 14.6 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.6 14.0 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.6 10.0 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.5 4.1 REACTOME OPSINS Genes involved in Opsins
0.5 6.5 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.4 11.6 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.3 4.8 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.2 5.9 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.2 4.1 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.2 4.6 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.2 7.0 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.2 1.7 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.2 14.3 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 1.9 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.1 1.7 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 2.0 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 1.0 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 1.7 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.1 1.7 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 3.2 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.1 1.4 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 2.9 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.1 2.8 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 2.1 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 2.5 REACTOME RIG I MDA5 MEDIATED INDUCTION OF IFN ALPHA BETA PATHWAYS Genes involved in RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
0.0 0.9 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.8 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.8 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.5 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 5.4 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 1.6 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 1.1 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 1.1 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.5 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis