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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Figla

Z-value: 0.90

Motif logo

Transcription factors associated with Figla

Gene Symbol Gene ID Gene Info
ENSMUSG00000030001.3 folliculogenesis specific basic helix-loop-helix

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Figlamm10_v2_chr6_+_86017191_86017229-0.173.1e-01Click!

Activity profile of Figla motif

Sorted Z-values of Figla motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Figla

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.0 GO:1990535 negative regulation of NAD(P)H oxidase activity(GO:0033861) neuron projection maintenance(GO:1990535)
1.0 2.9 GO:0051977 lysophospholipid transport(GO:0051977)
0.9 2.7 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.9 4.5 GO:0051594 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.4 0.4 GO:1901630 negative regulation of presynaptic membrane organization(GO:1901630)
0.4 1.2 GO:1904274 tricellular tight junction assembly(GO:1904274)
0.4 1.1 GO:0034635 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
0.4 1.1 GO:0006127 glycerophosphate shuttle(GO:0006127) glycerol-3-phosphate catabolic process(GO:0046168)
0.4 1.1 GO:2000314 negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.3 1.0 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.3 2.4 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.3 4.6 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.3 1.6 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.3 2.1 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.3 1.2 GO:0090472 dibasic protein processing(GO:0090472)
0.3 0.8 GO:2001293 malonyl-CoA metabolic process(GO:2001293)
0.2 0.7 GO:1904760 myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760)
0.2 0.9 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.2 0.7 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
0.2 1.1 GO:0009253 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253) negative regulation of natural killer cell differentiation(GO:0032824) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827)
0.2 2.3 GO:0005513 detection of calcium ion(GO:0005513)
0.2 0.6 GO:0014734 skeletal muscle hypertrophy(GO:0014734)
0.2 0.5 GO:1904057 negative regulation of sensory perception of pain(GO:1904057)
0.2 1.7 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.1 2.0 GO:0006751 glutathione catabolic process(GO:0006751)
0.1 0.4 GO:0099526 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
0.1 0.7 GO:0003383 apical constriction(GO:0003383)
0.1 0.6 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 0.3 GO:2000388 regulation of type IV hypersensitivity(GO:0001807) positive regulation of ovarian follicle development(GO:2000386) regulation of antral ovarian follicle growth(GO:2000387) positive regulation of antral ovarian follicle growth(GO:2000388)
0.1 0.6 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.1 1.3 GO:2000980 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.1 0.4 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
0.1 1.2 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.1 0.4 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.1 1.8 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.1 0.8 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.1 1.5 GO:0016264 gap junction assembly(GO:0016264)
0.1 0.4 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.1 0.3 GO:1901475 pyruvate transmembrane transport(GO:1901475)
0.1 0.3 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
0.1 0.4 GO:1903179 regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181)
0.1 0.7 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 0.6 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.1 1.0 GO:0060482 lobar bronchus epithelium development(GO:0060481) lobar bronchus development(GO:0060482)
0.1 0.6 GO:0045945 positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.1 1.3 GO:0015693 magnesium ion transport(GO:0015693)
0.1 0.7 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.1 1.2 GO:0019433 triglyceride catabolic process(GO:0019433)
0.1 0.3 GO:0097491 trigeminal nerve morphogenesis(GO:0021636) trigeminal nerve structural organization(GO:0021637) trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.1 0.5 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1 1.5 GO:0014002 astrocyte development(GO:0014002)
0.1 1.4 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 0.5 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.1 0.6 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.8 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 2.0 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.1 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.0 1.5 GO:0009649 entrainment of circadian clock(GO:0009649)
0.0 0.6 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.2 GO:0035740 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124) CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
0.0 0.2 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.0 0.2 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.0 0.3 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.0 0.3 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.1 GO:0019085 early viral transcription(GO:0019085)
0.0 0.1 GO:0048880 sensory system development(GO:0048880)
0.0 0.2 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 5.2 GO:0008203 cholesterol metabolic process(GO:0008203)
0.0 0.4 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 0.4 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 0.3 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.3 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.8 GO:0060396 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.0 0.1 GO:0035502 metanephric part of ureteric bud development(GO:0035502)
0.0 0.2 GO:0097527 necroptotic signaling pathway(GO:0097527)
0.0 0.1 GO:0050915 sensory perception of sour taste(GO:0050915)
0.0 0.3 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 0.1 GO:0090209 negative regulation of triglyceride metabolic process(GO:0090209)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.1 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.0 4.2 GO:0015758 glucose transport(GO:0015758)
0.0 0.1 GO:0032439 endosome localization(GO:0032439)
0.0 0.3 GO:0007320 insemination(GO:0007320)
0.0 1.1 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.1 GO:0042045 epithelial fluid transport(GO:0042045)
0.0 0.5 GO:0010763 positive regulation of fibroblast migration(GO:0010763)
0.0 0.6 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.0 1.6 GO:0055088 lipid homeostasis(GO:0055088)
0.0 1.7 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 0.4 GO:0051205 protein insertion into membrane(GO:0051205)
0.0 0.3 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 0.5 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.3 GO:0018195 peptidyl-arginine modification(GO:0018195)
0.0 0.3 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.5 GO:0007602 phototransduction(GO:0007602)
0.0 0.3 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895)
0.0 0.6 GO:0001523 retinoid metabolic process(GO:0001523)
0.0 0.2 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.1 GO:0044247 glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.0 0.0 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
0.0 0.1 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.4 GO:0031424 keratinization(GO:0031424)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0034667 integrin alpha3-beta1 complex(GO:0034667)
0.3 4.5 GO:0045180 basal cortex(GO:0045180)
0.2 1.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.2 0.6 GO:0036488 CHOP-C/EBP complex(GO:0036488)
0.2 4.5 GO:0042588 zymogen granule(GO:0042588)
0.1 0.4 GO:0044317 rod spherule(GO:0044317)
0.1 3.2 GO:0005922 connexon complex(GO:0005922)
0.1 2.3 GO:0031045 dense core granule(GO:0031045)
0.1 0.9 GO:0061689 tricellular tight junction(GO:0061689)
0.1 3.0 GO:0005732 small nucleolar ribonucleoprotein complex(GO:0005732)
0.1 0.3 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.1 1.8 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.1 1.8 GO:0032279 asymmetric synapse(GO:0032279)
0.1 0.7 GO:0045098 type III intermediate filament(GO:0045098)
0.1 0.2 GO:0032783 ELL-EAF complex(GO:0032783)
0.1 1.2 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.1 2.1 GO:0030673 axolemma(GO:0030673)
0.1 0.5 GO:0042587 glycogen granule(GO:0042587)
0.0 0.6 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 1.1 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.3 GO:0002081 outer acrosomal membrane(GO:0002081)
0.0 0.1 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 0.2 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.8 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.2 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.1 GO:0048179 activin receptor complex(GO:0048179)
0.0 1.3 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.6 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 1.2 GO:0016235 aggresome(GO:0016235)
0.0 0.4 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.9 GO:0097440 apical dendrite(GO:0097440)
0.0 0.8 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.3 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.3 GO:0035102 PRC1 complex(GO:0035102)
0.0 1.7 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.3 GO:0030056 hemidesmosome(GO:0030056)
0.0 3.2 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.1 GO:0034709 methylosome(GO:0034709)
0.0 1.2 GO:0005811 lipid particle(GO:0005811)
0.0 0.7 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.4 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.1 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.1 GO:0045179 apical cortex(GO:0045179)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.6 GO:0050253 sterol esterase activity(GO:0004771) retinyl-palmitate esterase activity(GO:0050253)
0.6 2.3 GO:0030348 syntaxin-3 binding(GO:0030348)
0.5 2.7 GO:0032810 sterol response element binding(GO:0032810)
0.4 4.5 GO:0004396 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396)
0.4 2.4 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.4 1.1 GO:0045159 myosin II binding(GO:0045159)
0.4 1.1 GO:0016901 glycerol-3-phosphate dehydrogenase activity(GO:0004368) oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.3 1.6 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.3 1.2 GO:0050436 microfibril binding(GO:0050436)
0.2 1.1 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745) peptidoglycan receptor activity(GO:0016019)
0.2 3.2 GO:0005243 gap junction channel activity(GO:0005243)
0.2 2.9 GO:0015245 fatty acid transporter activity(GO:0015245)
0.2 5.9 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.2 2.0 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.2 0.8 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.1 0.4 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.1 0.6 GO:0070404 NADH binding(GO:0070404)
0.1 6.8 GO:0005158 insulin receptor binding(GO:0005158)
0.1 0.3 GO:0032190 acrosin binding(GO:0032190)
0.1 0.7 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
0.1 0.6 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 0.2 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.1 0.3 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.1 1.2 GO:0048406 nerve growth factor binding(GO:0048406)
0.1 1.2 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 0.5 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.1 1.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 9.5 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 1.2 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.0 1.3 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 1.4 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.2 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.6 GO:0001013 RNA polymerase I regulatory region DNA binding(GO:0001013)
0.0 0.2 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.3 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.0 0.7 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.7 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.3 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 0.2 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.0 1.8 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.5 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.4 GO:0050897 cobalt ion binding(GO:0050897)
0.0 0.4 GO:0005522 profilin binding(GO:0005522)
0.0 0.3 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.3 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.4 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313)
0.0 3.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.3 GO:0016004 phospholipase activator activity(GO:0016004)
0.0 1.4 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.6 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.3 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.5 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.1 GO:0038100 nodal binding(GO:0038100)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.4 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.4 GO:0016594 glycine binding(GO:0016594)
0.0 0.1 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.4 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.5 GO:0030332 cyclin binding(GO:0030332)
0.0 1.0 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.1 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.0 0.6 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.7 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.3 GO:0032183 SUMO binding(GO:0032183)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.3 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.4 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 0.5 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 1.3 GO:0005179 hormone activity(GO:0005179)
0.0 0.3 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.6 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.3 GO:0008143 poly(A) binding(GO:0008143)
0.0 1.1 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 0.3 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 0.7 GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.0 0.1 GO:0015269 calcium-activated potassium channel activity(GO:0015269)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.9 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.1 2.7 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 2.3 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 9.4 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 2.1 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.2 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 1.7 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.4 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.2 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.4 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.5 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.4 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.8 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.5 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.9 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 1.2 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.5 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.3 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.2 3.2 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.1 1.1 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 4.5 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.1 2.1 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 0.5 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.1 1.2 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 2.9 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.9 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 1.5 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 1.8 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 1.0 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 3.4 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.4 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.9 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.6 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 1.3 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.4 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.8 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 1.3 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.2 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.6 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.8 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.7 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.3 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 1.0 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0 0.3 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo