avrg: GSE58827: Dynamics of the Mouse Liver
Gene Symbol | Gene ID | Gene Info |
---|---|---|
Hoxd11
|
ENSMUSG00000042499.12 | homeobox D11 |
Cdx1
|
ENSMUSG00000024619.8 | caudal type homeobox 1 |
Hoxc11
|
ENSMUSG00000001656.3 | homeobox C11 |
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Hoxc11 | mm10_v2_chr15_+_102954427_102954427 | 0.56 | 4.1e-04 | Click! |
Hoxd11 | mm10_v2_chr2_+_74681991_74682007 | 0.51 | 1.6e-03 | Click! |
Cdx1 | mm10_v2_chr18_-_61036189_61036210 | 0.35 | 3.7e-02 | Click! |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
3.6 | 14.3 | GO:0045575 | basophil activation(GO:0045575) |
3.3 | 26.0 | GO:0038028 | insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) |
1.6 | 6.3 | GO:1903225 | negative regulation of endodermal cell differentiation(GO:1903225) |
1.4 | 4.2 | GO:0002314 | germinal center B cell differentiation(GO:0002314) |
1.4 | 4.1 | GO:0007208 | phospholipase C-activating serotonin receptor signaling pathway(GO:0007208) |
1.4 | 6.8 | GO:0045163 | clustering of voltage-gated potassium channels(GO:0045163) |
1.3 | 5.1 | GO:0035524 | proline transmembrane transport(GO:0035524) |
1.0 | 4.1 | GO:0015801 | aromatic amino acid transport(GO:0015801) tryptophan transport(GO:0015827) |
1.0 | 1.9 | GO:0070560 | protein secretion by platelet(GO:0070560) |
0.8 | 2.5 | GO:0046098 | guanine metabolic process(GO:0046098) |
0.8 | 8.3 | GO:0090527 | actin filament reorganization(GO:0090527) |
0.8 | 2.4 | GO:0060489 | orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490) |
0.7 | 2.7 | GO:1902953 | positive regulation of ER to Golgi vesicle-mediated transport(GO:1902953) positive regulation of endocytic recycling(GO:2001137) |
0.7 | 5.3 | GO:0021555 | midbrain-hindbrain boundary morphogenesis(GO:0021555) |
0.7 | 10.6 | GO:0071688 | striated muscle myosin thick filament assembly(GO:0071688) |
0.6 | 1.8 | GO:0003345 | proepicardium cell migration involved in pericardium morphogenesis(GO:0003345) |
0.5 | 2.7 | GO:1904970 | brush border assembly(GO:1904970) |
0.4 | 3.1 | GO:1901678 | iron coordination entity transport(GO:1901678) |
0.4 | 1.3 | GO:1902256 | apoptotic process involved in outflow tract morphogenesis(GO:0003275) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256) |
0.4 | 1.6 | GO:0014012 | peripheral nervous system axon regeneration(GO:0014012) |
0.4 | 2.4 | GO:0038128 | ERBB2 signaling pathway(GO:0038128) |
0.4 | 2.6 | GO:0021615 | glossopharyngeal nerve morphogenesis(GO:0021615) |
0.4 | 1.1 | GO:0036292 | DNA rewinding(GO:0036292) |
0.4 | 1.1 | GO:1905000 | regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000) |
0.3 | 1.7 | GO:1903566 | positive regulation of protein localization to cilium(GO:1903566) |
0.3 | 4.8 | GO:0042118 | endothelial cell activation(GO:0042118) |
0.3 | 0.9 | GO:0030210 | heparin biosynthetic process(GO:0030210) |
0.3 | 3.2 | GO:0035092 | sperm chromatin condensation(GO:0035092) |
0.3 | 4.0 | GO:0090336 | positive regulation of brown fat cell differentiation(GO:0090336) |
0.3 | 9.0 | GO:0006825 | copper ion transport(GO:0006825) |
0.3 | 3.8 | GO:0048664 | neuron fate determination(GO:0048664) |
0.2 | 1.0 | GO:0035589 | G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589) |
0.2 | 1.2 | GO:0019516 | lactate oxidation(GO:0019516) |
0.2 | 3.9 | GO:2000096 | positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096) |
0.2 | 2.1 | GO:0048539 | bone marrow development(GO:0048539) |
0.2 | 3.0 | GO:0060923 | cardiac muscle cell fate commitment(GO:0060923) |
0.2 | 2.3 | GO:0030206 | chondroitin sulfate biosynthetic process(GO:0030206) |
0.2 | 1.1 | GO:0003278 | apoptotic process involved in heart morphogenesis(GO:0003278) |
0.2 | 1.4 | GO:0009098 | branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099) |
0.2 | 0.9 | GO:0015770 | disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772) |
0.2 | 3.1 | GO:0035970 | peptidyl-threonine dephosphorylation(GO:0035970) |
0.2 | 2.0 | GO:1990253 | cellular response to leucine starvation(GO:1990253) |
0.2 | 1.2 | GO:0006207 | 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856) |
0.2 | 1.2 | GO:0010288 | response to lead ion(GO:0010288) |
0.2 | 2.1 | GO:0045617 | negative regulation of keratinocyte differentiation(GO:0045617) |
0.2 | 2.0 | GO:0010650 | positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827) |
0.2 | 0.9 | GO:0019371 | cyclooxygenase pathway(GO:0019371) maintenance of blood-brain barrier(GO:0035633) |
0.2 | 0.5 | GO:0060821 | inactivation of X chromosome by DNA methylation(GO:0060821) |
0.2 | 5.3 | GO:0051482 | positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482) |
0.1 | 1.8 | GO:0016446 | somatic hypermutation of immunoglobulin genes(GO:0016446) |
0.1 | 2.5 | GO:0045332 | phospholipid translocation(GO:0045332) |
0.1 | 1.0 | GO:0031848 | protection from non-homologous end joining at telomere(GO:0031848) |
0.1 | 0.6 | GO:0002386 | immune response in mucosal-associated lymphoid tissue(GO:0002386) |
0.1 | 1.1 | GO:0018344 | protein geranylgeranylation(GO:0018344) |
0.1 | 0.6 | GO:0060697 | positive regulation of phospholipid catabolic process(GO:0060697) |
0.1 | 0.5 | GO:0048686 | regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690) |
0.1 | 0.4 | GO:0014846 | esophagus smooth muscle contraction(GO:0014846) |
0.1 | 0.9 | GO:0043654 | recognition of apoptotic cell(GO:0043654) |
0.1 | 0.6 | GO:1902748 | positive regulation of lens fiber cell differentiation(GO:1902748) |
0.1 | 6.1 | GO:0070303 | negative regulation of stress-activated MAPK cascade(GO:0032873) negative regulation of stress-activated protein kinase signaling cascade(GO:0070303) |
0.1 | 5.8 | GO:0045197 | establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197) |
0.1 | 0.6 | GO:1903054 | negative regulation of extracellular matrix organization(GO:1903054) |
0.1 | 1.8 | GO:0001833 | inner cell mass cell proliferation(GO:0001833) |
0.1 | 0.2 | GO:0061591 | calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591) |
0.1 | 1.2 | GO:1902083 | negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083) |
0.1 | 1.3 | GO:1900121 | negative regulation of receptor binding(GO:1900121) |
0.1 | 1.1 | GO:0090110 | cargo loading into COPII-coated vesicle(GO:0090110) |
0.1 | 0.9 | GO:0006527 | arginine catabolic process(GO:0006527) |
0.1 | 0.4 | GO:0010735 | positive regulation of transcription via serum response element binding(GO:0010735) |
0.1 | 1.9 | GO:0035855 | megakaryocyte development(GO:0035855) |
0.1 | 2.7 | GO:0046854 | phosphatidylinositol phosphorylation(GO:0046854) |
0.1 | 1.5 | GO:0043968 | histone H2A acetylation(GO:0043968) |
0.1 | 1.2 | GO:0040034 | regulation of development, heterochronic(GO:0040034) |
0.1 | 2.9 | GO:0050869 | negative regulation of B cell activation(GO:0050869) |
0.1 | 8.2 | GO:0043488 | regulation of mRNA stability(GO:0043488) |
0.1 | 0.6 | GO:0010587 | miRNA catabolic process(GO:0010587) |
0.1 | 2.5 | GO:0045648 | positive regulation of erythrocyte differentiation(GO:0045648) |
0.1 | 2.2 | GO:1905144 | acetylcholine receptor signaling pathway(GO:0095500) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145) |
0.1 | 5.2 | GO:0070936 | protein K48-linked ubiquitination(GO:0070936) |
0.1 | 1.3 | GO:0021516 | dorsal spinal cord development(GO:0021516) |
0.1 | 2.3 | GO:0019236 | response to pheromone(GO:0019236) |
0.1 | 3.9 | GO:0006414 | translational elongation(GO:0006414) |
0.1 | 1.4 | GO:0043374 | CD8-positive, alpha-beta T cell differentiation(GO:0043374) |
0.1 | 3.5 | GO:1902476 | chloride transmembrane transport(GO:1902476) |
0.1 | 2.1 | GO:0002026 | regulation of the force of heart contraction(GO:0002026) |
0.1 | 0.6 | GO:0032261 | purine nucleotide salvage(GO:0032261) IMP salvage(GO:0032264) |
0.1 | 0.1 | GO:0043490 | malate-aspartate shuttle(GO:0043490) |
0.1 | 1.3 | GO:0008272 | sulfate transport(GO:0008272) |
0.1 | 0.5 | GO:0061621 | NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718) |
0.1 | 0.9 | GO:1900153 | regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153) |
0.1 | 4.5 | GO:0030239 | myofibril assembly(GO:0030239) |
0.1 | 0.2 | GO:0010578 | regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579) |
0.1 | 0.6 | GO:0042541 | hemoglobin biosynthetic process(GO:0042541) |
0.1 | 1.1 | GO:0014823 | response to activity(GO:0014823) |
0.1 | 2.9 | GO:0016574 | histone ubiquitination(GO:0016574) |
0.0 | 1.1 | GO:0045616 | regulation of keratinocyte differentiation(GO:0045616) |
0.0 | 1.1 | GO:2001224 | positive regulation of neuron migration(GO:2001224) |
0.0 | 0.4 | GO:0000395 | mRNA 5'-splice site recognition(GO:0000395) |
0.0 | 0.5 | GO:0010459 | negative regulation of heart rate(GO:0010459) |
0.0 | 0.7 | GO:0007202 | activation of phospholipase C activity(GO:0007202) |
0.0 | 1.0 | GO:0003351 | epithelial cilium movement(GO:0003351) |
0.0 | 0.8 | GO:0035493 | SNARE complex assembly(GO:0035493) |
0.0 | 0.7 | GO:0001580 | detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580) |
0.0 | 0.3 | GO:0014029 | neural crest formation(GO:0014029) |
0.0 | 0.1 | GO:0060729 | intestinal epithelial structure maintenance(GO:0060729) |
0.0 | 0.3 | GO:1900034 | regulation of cellular response to heat(GO:1900034) |
0.0 | 1.9 | GO:0006821 | chloride transport(GO:0006821) |
0.0 | 0.2 | GO:0016584 | nucleosome positioning(GO:0016584) histone H3-K27 trimethylation(GO:0098532) |
0.0 | 1.2 | GO:0010972 | negative regulation of G2/M transition of mitotic cell cycle(GO:0010972) |
0.0 | 1.3 | GO:0048873 | homeostasis of number of cells within a tissue(GO:0048873) |
0.0 | 0.1 | GO:0002282 | microglial cell activation involved in immune response(GO:0002282) |
0.0 | 1.4 | GO:1901998 | toxin transport(GO:1901998) |
0.0 | 0.8 | GO:0071353 | cellular response to interleukin-4(GO:0071353) |
0.0 | 0.1 | GO:0006713 | glucocorticoid catabolic process(GO:0006713) |
0.0 | 0.2 | GO:0006362 | transcription elongation from RNA polymerase I promoter(GO:0006362) |
0.0 | 0.1 | GO:1902261 | positive regulation of delayed rectifier potassium channel activity(GO:1902261) |
0.0 | 1.1 | GO:0015914 | phospholipid transport(GO:0015914) |
0.0 | 0.3 | GO:0034391 | smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391) |
0.0 | 2.7 | GO:0051928 | positive regulation of calcium ion transport(GO:0051928) |
0.0 | 0.1 | GO:0051001 | negative regulation of nitric-oxide synthase activity(GO:0051001) |
0.0 | 1.2 | GO:0006493 | protein O-linked glycosylation(GO:0006493) |
0.0 | 0.2 | GO:0035878 | nail development(GO:0035878) |
0.0 | 0.2 | GO:0018230 | peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231) |
0.0 | 0.2 | GO:0010804 | negative regulation of tumor necrosis factor-mediated signaling pathway(GO:0010804) |
0.0 | 0.2 | GO:0043653 | mitochondrial fragmentation involved in apoptotic process(GO:0043653) |
0.0 | 0.1 | GO:2000224 | regulation of testosterone biosynthetic process(GO:2000224) |
0.0 | 0.8 | GO:0048599 | oocyte development(GO:0048599) |
0.0 | 0.3 | GO:0007175 | negative regulation of epidermal growth factor-activated receptor activity(GO:0007175) |
0.0 | 0.4 | GO:0008206 | bile acid metabolic process(GO:0008206) |
0.0 | 0.3 | GO:2000649 | regulation of sodium ion transmembrane transporter activity(GO:2000649) |
0.0 | 0.1 | GO:1902572 | regulation of serine-type endopeptidase activity(GO:1900003) negative regulation of serine-type endopeptidase activity(GO:1900004) regulation of serine-type peptidase activity(GO:1902571) negative regulation of serine-type peptidase activity(GO:1902572) |
0.0 | 0.1 | GO:0002759 | regulation of antimicrobial humoral response(GO:0002759) |
0.0 | 0.6 | GO:0009954 | proximal/distal pattern formation(GO:0009954) |
0.0 | 1.2 | GO:0030168 | platelet activation(GO:0030168) |
0.0 | 1.3 | GO:0007093 | mitotic cell cycle checkpoint(GO:0007093) |
0.0 | 1.1 | GO:1900181 | negative regulation of protein localization to nucleus(GO:1900181) |
0.0 | 0.1 | GO:1900383 | regulation of synaptic plasticity by receptor localization to synapse(GO:1900383) |
0.0 | 0.1 | GO:0061635 | regulation of protein complex stability(GO:0061635) |
0.0 | 0.2 | GO:0008053 | mitochondrial fusion(GO:0008053) |
0.0 | 0.2 | GO:0048679 | regulation of axon regeneration(GO:0048679) |
0.0 | 3.2 | GO:0016358 | dendrite development(GO:0016358) |
0.0 | 1.3 | GO:0001508 | action potential(GO:0001508) |
0.0 | 1.1 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.1 | 6.3 | GO:0005588 | collagen type V trimer(GO:0005588) |
0.7 | 5.9 | GO:0097427 | microtubule bundle(GO:0097427) |
0.7 | 3.9 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
0.6 | 2.4 | GO:0060187 | cell pole(GO:0060187) |
0.6 | 15.7 | GO:0032982 | myosin filament(GO:0032982) |
0.5 | 1.5 | GO:1990423 | RZZ complex(GO:1990423) |
0.4 | 2.0 | GO:1990131 | Gtr1-Gtr2 GTPase complex(GO:1990131) |
0.4 | 3.7 | GO:0001739 | sex chromatin(GO:0001739) |
0.3 | 4.9 | GO:0042589 | zymogen granule membrane(GO:0042589) |
0.3 | 1.5 | GO:0032777 | Piccolo NuA4 histone acetyltransferase complex(GO:0032777) |
0.3 | 4.1 | GO:0070852 | cell body fiber(GO:0070852) |
0.2 | 1.1 | GO:0031523 | Myb complex(GO:0031523) |
0.2 | 1.1 | GO:0005968 | Rab-protein geranylgeranyltransferase complex(GO:0005968) |
0.2 | 0.8 | GO:0070820 | tertiary granule(GO:0070820) |
0.2 | 0.8 | GO:0070022 | transforming growth factor beta receptor homodimeric complex(GO:0070022) |
0.2 | 0.5 | GO:0072534 | perineuronal net(GO:0072534) |
0.2 | 2.7 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
0.1 | 2.3 | GO:0032580 | Golgi cisterna membrane(GO:0032580) |
0.1 | 1.5 | GO:0033093 | Weibel-Palade body(GO:0033093) |
0.1 | 2.5 | GO:0016460 | myosin II complex(GO:0016460) |
0.1 | 2.0 | GO:0014731 | spectrin-associated cytoskeleton(GO:0014731) |
0.1 | 1.1 | GO:0030127 | COPII vesicle coat(GO:0030127) |
0.1 | 0.6 | GO:1990357 | terminal web(GO:1990357) |
0.1 | 0.5 | GO:0001740 | Barr body(GO:0001740) |
0.1 | 4.4 | GO:0016235 | aggresome(GO:0016235) |
0.1 | 3.1 | GO:0031672 | A band(GO:0031672) |
0.1 | 6.8 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
0.1 | 0.6 | GO:0034366 | spherical high-density lipoprotein particle(GO:0034366) |
0.1 | 1.3 | GO:0005922 | connexon complex(GO:0005922) |
0.1 | 0.6 | GO:0031258 | lamellipodium membrane(GO:0031258) |
0.1 | 2.7 | GO:0008023 | transcription elongation factor complex(GO:0008023) |
0.0 | 2.3 | GO:1990391 | DNA repair complex(GO:1990391) |
0.0 | 12.9 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
0.0 | 5.1 | GO:0055037 | recycling endosome(GO:0055037) |
0.0 | 0.4 | GO:0000243 | commitment complex(GO:0000243) |
0.0 | 0.9 | GO:0001891 | phagocytic cup(GO:0001891) |
0.0 | 3.6 | GO:0030018 | Z disc(GO:0030018) |
0.0 | 1.2 | GO:0043596 | nuclear replication fork(GO:0043596) |
0.0 | 4.2 | GO:0005903 | brush border(GO:0005903) |
0.0 | 0.8 | GO:0044298 | neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298) |
0.0 | 2.4 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
0.0 | 1.8 | GO:0001750 | photoreceptor outer segment(GO:0001750) |
0.0 | 0.6 | GO:0005942 | phosphatidylinositol 3-kinase complex(GO:0005942) |
0.0 | 0.4 | GO:0033276 | transcription factor TFTC complex(GO:0033276) |
0.0 | 2.5 | GO:0005814 | centriole(GO:0005814) |
0.0 | 1.0 | GO:0005871 | kinesin complex(GO:0005871) |
0.0 | 3.3 | GO:0031225 | anchored component of membrane(GO:0031225) |
0.0 | 2.0 | GO:0016363 | nuclear matrix(GO:0016363) |
0.0 | 0.6 | GO:0005771 | multivesicular body(GO:0005771) |
0.0 | 1.8 | GO:0032587 | ruffle membrane(GO:0032587) |
0.0 | 0.5 | GO:0060170 | ciliary membrane(GO:0060170) |
0.0 | 3.3 | GO:0030427 | site of polarized growth(GO:0030427) |
0.0 | 0.4 | GO:0005614 | interstitial matrix(GO:0005614) |
0.0 | 1.6 | GO:0030496 | midbody(GO:0030496) |
0.0 | 0.3 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
0.0 | 1.7 | GO:0005923 | bicellular tight junction(GO:0005923) |
0.0 | 0.1 | GO:0000444 | MIS12/MIND type complex(GO:0000444) |
0.0 | 20.4 | GO:0005615 | extracellular space(GO:0005615) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.4 | 4.2 | GO:0035673 | oligopeptide transmembrane transporter activity(GO:0035673) |
1.4 | 6.8 | GO:0005250 | A-type (transient outward) potassium channel activity(GO:0005250) |
0.9 | 4.4 | GO:0051373 | FATZ binding(GO:0051373) |
0.8 | 8.5 | GO:0004322 | ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724) |
0.8 | 2.3 | GO:0050510 | N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510) |
0.8 | 5.3 | GO:0070915 | lysophosphatidic acid receptor activity(GO:0070915) |
0.7 | 26.6 | GO:0005159 | insulin-like growth factor receptor binding(GO:0005159) |
0.6 | 4.4 | GO:0016936 | galactoside binding(GO:0016936) |
0.6 | 4.1 | GO:0008241 | peptidyl-dipeptidase activity(GO:0008241) |
0.6 | 10.6 | GO:0097493 | structural molecule activity conferring elasticity(GO:0097493) |
0.5 | 2.5 | GO:0034648 | histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648) |
0.5 | 5.1 | GO:0015193 | L-proline transmembrane transporter activity(GO:0015193) |
0.4 | 1.2 | GO:0004088 | carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088) |
0.3 | 4.1 | GO:0051378 | serotonin binding(GO:0051378) |
0.3 | 6.1 | GO:0050321 | tau-protein kinase activity(GO:0050321) |
0.3 | 6.1 | GO:0005229 | intracellular calcium activated chloride channel activity(GO:0005229) |
0.3 | 1.2 | GO:0001087 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087) |
0.3 | 4.1 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
0.3 | 0.8 | GO:0050429 | calcium-dependent phospholipase C activity(GO:0050429) |
0.2 | 2.7 | GO:0030306 | ADP-ribosylation factor binding(GO:0030306) |
0.2 | 2.2 | GO:0030550 | acetylcholine receptor inhibitor activity(GO:0030550) |
0.2 | 1.4 | GO:0052656 | branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656) |
0.2 | 1.1 | GO:0034988 | mu-type opioid receptor binding(GO:0031852) Fc-gamma receptor I complex binding(GO:0034988) |
0.2 | 0.9 | GO:0008515 | sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157) |
0.2 | 0.6 | GO:0016748 | succinyltransferase activity(GO:0016748) |
0.2 | 1.1 | GO:0030280 | structural constituent of epidermis(GO:0030280) |
0.2 | 5.3 | GO:0030159 | receptor signaling complex scaffold activity(GO:0030159) |
0.2 | 1.6 | GO:0045545 | syndecan binding(GO:0045545) |
0.2 | 1.2 | GO:0008422 | beta-glucosidase activity(GO:0008422) |
0.2 | 1.8 | GO:0051575 | 5'-deoxyribose-5-phosphate lyase activity(GO:0051575) |
0.2 | 1.2 | GO:0004459 | L-lactate dehydrogenase activity(GO:0004459) |
0.2 | 3.9 | GO:0003746 | translation elongation factor activity(GO:0003746) |
0.1 | 3.0 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
0.1 | 6.2 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
0.1 | 16.1 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
0.1 | 2.8 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
0.1 | 0.6 | GO:0050265 | RNA uridylyltransferase activity(GO:0050265) |
0.1 | 0.9 | GO:0008454 | alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454) |
0.1 | 0.7 | GO:1990932 | 5.8S rRNA binding(GO:1990932) |
0.1 | 3.6 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
0.1 | 1.0 | GO:0035312 | 5'-3' exodeoxyribonuclease activity(GO:0035312) |
0.1 | 1.8 | GO:0045499 | chemorepellent activity(GO:0045499) |
0.1 | 0.3 | GO:0019959 | interleukin-8 binding(GO:0019959) |
0.1 | 9.9 | GO:0001190 | transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811) |
0.1 | 1.1 | GO:0036310 | annealing helicase activity(GO:0036310) |
0.1 | 1.5 | GO:0019865 | immunoglobulin binding(GO:0019865) |
0.1 | 1.8 | GO:0005523 | tropomyosin binding(GO:0005523) |
0.1 | 1.1 | GO:0003680 | AT DNA binding(GO:0003680) |
0.1 | 0.4 | GO:0004574 | oligo-1,6-glucosidase activity(GO:0004574) |
0.1 | 0.4 | GO:0008449 | N-acetylglucosamine-6-sulfatase activity(GO:0008449) |
0.1 | 0.8 | GO:0098748 | clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
0.1 | 8.2 | GO:0003730 | mRNA 3'-UTR binding(GO:0003730) |
0.1 | 0.6 | GO:0060230 | lipoprotein lipase activator activity(GO:0060230) |
0.1 | 0.9 | GO:0016813 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813) |
0.1 | 0.7 | GO:0033691 | sialic acid binding(GO:0033691) |
0.1 | 0.6 | GO:0052851 | ferric-chelate reductase activity(GO:0000293) cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851) |
0.1 | 0.8 | GO:0097027 | ubiquitin-protein transferase activator activity(GO:0097027) |
0.1 | 1.0 | GO:0001608 | G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028) |
0.1 | 1.7 | GO:0043422 | protein kinase B binding(GO:0043422) |
0.1 | 1.3 | GO:0008271 | secondary active sulfate transmembrane transporter activity(GO:0008271) |
0.1 | 1.1 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
0.1 | 0.6 | GO:0003876 | AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623) |
0.1 | 0.3 | GO:0008061 | chitin binding(GO:0008061) |
0.1 | 5.0 | GO:0048365 | Rac GTPase binding(GO:0048365) |
0.1 | 1.1 | GO:0005092 | GDP-dissociation inhibitor activity(GO:0005092) |
0.1 | 0.2 | GO:0051377 | mannose-ethanolamine phosphotransferase activity(GO:0051377) |
0.1 | 2.1 | GO:0003785 | actin monomer binding(GO:0003785) |
0.0 | 0.3 | GO:0048101 | calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101) |
0.0 | 13.1 | GO:0030246 | carbohydrate binding(GO:0030246) |
0.0 | 0.2 | GO:0001165 | RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165) |
0.0 | 7.6 | GO:0003774 | motor activity(GO:0003774) |
0.0 | 0.4 | GO:1990446 | U1 snRNP binding(GO:1990446) |
0.0 | 0.5 | GO:0046625 | sphingolipid binding(GO:0046625) |
0.0 | 0.8 | GO:0008510 | sodium:bicarbonate symporter activity(GO:0008510) |
0.0 | 0.7 | GO:0005172 | vascular endothelial growth factor receptor binding(GO:0005172) |
0.0 | 2.5 | GO:0001784 | phosphotyrosine binding(GO:0001784) |
0.0 | 0.2 | GO:0038132 | neuregulin binding(GO:0038132) |
0.0 | 0.1 | GO:0015183 | L-aspartate transmembrane transporter activity(GO:0015183) |
0.0 | 0.7 | GO:0015026 | coreceptor activity(GO:0015026) |
0.0 | 0.1 | GO:0051431 | corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 2 binding(GO:0051431) |
0.0 | 2.7 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
0.0 | 0.6 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
0.0 | 1.9 | GO:0004402 | histone acetyltransferase activity(GO:0004402) |
0.0 | 0.4 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
0.0 | 0.6 | GO:0070412 | R-SMAD binding(GO:0070412) |
0.0 | 1.0 | GO:0005044 | scavenger receptor activity(GO:0005044) |
0.0 | 2.4 | GO:0033613 | activating transcription factor binding(GO:0033613) |
0.0 | 0.2 | GO:0032564 | dATP binding(GO:0032564) |
0.0 | 1.8 | GO:0008146 | sulfotransferase activity(GO:0008146) |
0.0 | 1.9 | GO:0005080 | protein kinase C binding(GO:0005080) |
0.0 | 2.4 | GO:0000979 | RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979) |
0.0 | 2.8 | GO:0003705 | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705) |
0.0 | 0.7 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
0.0 | 0.8 | GO:0005484 | SNAP receptor activity(GO:0005484) |
0.0 | 0.3 | GO:0008307 | structural constituent of muscle(GO:0008307) |
0.0 | 2.3 | GO:0002020 | protease binding(GO:0002020) |
0.0 | 0.9 | GO:0004601 | peroxidase activity(GO:0004601) |
0.0 | 1.4 | GO:0004725 | protein tyrosine phosphatase activity(GO:0004725) |
0.0 | 0.1 | GO:0005068 | transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068) |
0.0 | 0.2 | GO:0051400 | BH domain binding(GO:0051400) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 28.1 | PID AJDISS 2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
0.3 | 10.3 | PID INTEGRIN A9B1 PATHWAY | Alpha9 beta1 integrin signaling events |
0.3 | 12.8 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
0.3 | 5.3 | PID LPA4 PATHWAY | LPA4-mediated signaling events |
0.1 | 5.1 | PID SYNDECAN 1 PATHWAY | Syndecan-1-mediated signaling events |
0.1 | 8.1 | PID NOTCH PATHWAY | Notch signaling pathway |
0.1 | 3.2 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
0.0 | 0.8 | PID PRL SIGNALING EVENTS PATHWAY | Signaling events mediated by PRL |
0.0 | 0.6 | PID ANTHRAX PATHWAY | Cellular roles of Anthrax toxin |
0.0 | 2.1 | PID ATF2 PATHWAY | ATF-2 transcription factor network |
0.0 | 0.6 | PID EPHA2 FWD PATHWAY | EPHA2 forward signaling |
0.0 | 7.6 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
0.0 | 3.3 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
0.0 | 2.8 | PID P73PATHWAY | p73 transcription factor network |
0.0 | 4.8 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
0.0 | 0.5 | PID HDAC CLASSIII PATHWAY | Signaling events mediated by HDAC Class III |
0.0 | 0.9 | PID ANGIOPOIETIN RECEPTOR PATHWAY | Angiopoietin receptor Tie2-mediated signaling |
0.0 | 1.5 | PID ERA GENOMIC PATHWAY | Validated nuclear estrogen receptor alpha network |
0.0 | 0.7 | PID BMP PATHWAY | BMP receptor signaling |
0.0 | 1.5 | PID MTOR 4PATHWAY | mTOR signaling pathway |
0.0 | 1.2 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
0.0 | 0.2 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
0.0 | 1.3 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
0.0 | 0.6 | ST WNT BETA CATENIN PATHWAY | Wnt/beta-catenin Pathway |
0.0 | 2.6 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
0.0 | 0.1 | SA B CELL RECEPTOR COMPLEXES | Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases. |
0.0 | 0.3 | PID IL8 CXCR1 PATHWAY | IL8- and CXCR1-mediated signaling events |
0.0 | 0.5 | PID IL4 2PATHWAY | IL4-mediated signaling events |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.2 | 26.0 | REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
0.4 | 5.3 | REACTOME P2Y RECEPTORS | Genes involved in P2Y receptors |
0.4 | 4.1 | REACTOME SEROTONIN RECEPTORS | Genes involved in Serotonin receptors |
0.2 | 8.5 | REACTOME METAL ION SLC TRANSPORTERS | Genes involved in Metal ion SLC transporters |
0.1 | 2.3 | REACTOME CHONDROITIN SULFATE BIOSYNTHESIS | Genes involved in Chondroitin sulfate biosynthesis |
0.1 | 1.5 | REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN | Genes involved in Platelet Adhesion to exposed collagen |
0.1 | 5.1 | REACTOME NCAM1 INTERACTIONS | Genes involved in NCAM1 interactions |
0.1 | 1.3 | REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
0.1 | 1.3 | REACTOME GAP JUNCTION ASSEMBLY | Genes involved in Gap junction assembly |
0.1 | 2.9 | REACTOME TIGHT JUNCTION INTERACTIONS | Genes involved in Tight junction interactions |
0.1 | 1.4 | REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
0.1 | 1.5 | REACTOME TIE2 SIGNALING | Genes involved in Tie2 Signaling |
0.1 | 0.8 | REACTOME GAP JUNCTION TRAFFICKING | Genes involved in Gap junction trafficking |
0.1 | 0.8 | REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS | Genes involved in Proteolytic cleavage of SNARE complex proteins |
0.1 | 1.1 | REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC | Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC |
0.1 | 0.9 | REACTOME N GLYCAN ANTENNAE ELONGATION | Genes involved in N-Glycan antennae elongation |
0.1 | 3.1 | REACTOME O LINKED GLYCOSYLATION OF MUCINS | Genes involved in O-linked glycosylation of mucins |
0.0 | 7.7 | REACTOME SIGNALING BY EGFR IN CANCER | Genes involved in Signaling by EGFR in Cancer |
0.0 | 0.8 | REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY | Genes involved in Post-chaperonin tubulin folding pathway |
0.0 | 2.1 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
0.0 | 1.8 | REACTOME STRIATED MUSCLE CONTRACTION | Genes involved in Striated Muscle Contraction |
0.0 | 1.7 | REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT | Genes involved in ABC-family proteins mediated transport |
0.0 | 1.4 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
0.0 | 0.6 | REACTOME PURINE SALVAGE | Genes involved in Purine salvage |
0.0 | 0.6 | REACTOME METABOLISM OF PORPHYRINS | Genes involved in Metabolism of porphyrins |
0.0 | 4.6 | REACTOME TRANSLATION | Genes involved in Translation |
0.0 | 0.6 | REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
0.0 | 0.9 | REACTOME MYOGENESIS | Genes involved in Myogenesis |
0.0 | 1.4 | REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS | Genes involved in Apoptotic cleavage of cellular proteins |
0.0 | 1.7 | REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | Genes involved in Response to elevated platelet cytosolic Ca2+ |
0.0 | 2.5 | REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION | Genes involved in Factors involved in megakaryocyte development and platelet production |
0.0 | 0.6 | REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING | Genes involved in Transferrin endocytosis and recycling |
0.0 | 1.3 | REACTOME INTEGRIN CELL SURFACE INTERACTIONS | Genes involved in Integrin cell surface interactions |
0.0 | 0.2 | REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION | Genes involved in Apoptosis induced DNA fragmentation |
0.0 | 0.1 | REACTOME REGULATION OF SIGNALING BY CBL | Genes involved in Regulation of signaling by CBL |
0.0 | 0.0 | REACTOME DIGESTION OF DIETARY CARBOHYDRATE | Genes involved in Digestion of dietary carbohydrate |
0.0 | 0.4 | REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING | Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening |
0.0 | 0.4 | REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION | Genes involved in Glucagon signaling in metabolic regulation |