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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Nr2e3

Z-value: 1.35

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Transcription factors associated with Nr2e3

Gene Symbol Gene ID Gene Info
ENSMUSG00000032292.2 nuclear receptor subfamily 2, group E, member 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nr2e3mm10_v2_chr9_-_59950068_599501220.492.4e-03Click!

Activity profile of Nr2e3 motif

Sorted Z-values of Nr2e3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Nr2e3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 9.2 GO:0070488 neutrophil aggregation(GO:0070488)
1.5 6.0 GO:0035524 proline transmembrane transport(GO:0035524) glycine import(GO:0036233)
1.2 3.5 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.9 6.4 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.9 2.7 GO:0003345 proepicardium cell migration involved in pericardium morphogenesis(GO:0003345)
0.8 6.3 GO:0097647 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.8 2.4 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.6 3.1 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.5 1.9 GO:0035905 ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
0.5 1.4 GO:2001076 negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302) regulation of metanephric ureteric bud development(GO:2001074) positive regulation of metanephric ureteric bud development(GO:2001076)
0.5 5.5 GO:0046549 retinal cone cell development(GO:0046549)
0.4 1.3 GO:0070340 detection of bacterial lipopeptide(GO:0070340)
0.4 7.0 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.4 2.0 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.4 2.0 GO:0002121 inter-male aggressive behavior(GO:0002121)
0.4 3.6 GO:0010587 miRNA catabolic process(GO:0010587)
0.4 1.2 GO:0060821 inactivation of X chromosome by DNA methylation(GO:0060821)
0.3 1.3 GO:0061153 negative regulation of interleukin-13 production(GO:0032696) trachea submucosa development(GO:0061152) trachea gland development(GO:0061153) odontoblast differentiation(GO:0071895) regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899)
0.3 1.3 GO:1902606 regulation of large conductance calcium-activated potassium channel activity(GO:1902606) positive regulation of large conductance calcium-activated potassium channel activity(GO:1902608)
0.3 1.9 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.3 0.9 GO:0051794 regulation of catagen(GO:0051794)
0.3 2.4 GO:0015671 oxygen transport(GO:0015671)
0.3 1.9 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.3 1.1 GO:0032053 ciliary basal body organization(GO:0032053)
0.3 1.4 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313)
0.3 1.0 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.2 1.5 GO:0032346 positive regulation of aldosterone metabolic process(GO:0032346) positive regulation of aldosterone biosynthetic process(GO:0032349) leading edge cell differentiation(GO:0035026)
0.2 0.9 GO:0030070 insulin processing(GO:0030070)
0.2 1.2 GO:0038032 termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.2 1.6 GO:2000002 negative regulation of DNA damage checkpoint(GO:2000002)
0.2 0.6 GO:0046087 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.2 1.6 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.2 0.6 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.2 0.6 GO:0045726 positive regulation of integrin biosynthetic process(GO:0045726)
0.2 1.5 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) negative regulation of serotonin uptake(GO:0051612)
0.2 0.5 GO:0002223 stimulatory C-type lectin receptor signaling pathway(GO:0002223)
0.2 2.7 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.1 1.5 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.1 0.6 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.1 1.4 GO:0090527 actin filament reorganization(GO:0090527)
0.1 0.7 GO:0098886 modification of dendritic spine(GO:0098886)
0.1 2.7 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.1 0.6 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 1.9 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.1 1.0 GO:0032532 regulation of microvillus length(GO:0032532)
0.1 4.5 GO:0019731 antibacterial humoral response(GO:0019731)
0.1 0.3 GO:0097401 synaptic vesicle lumen acidification(GO:0097401)
0.1 0.4 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.1 0.3 GO:0032849 positive regulation of cellular pH reduction(GO:0032849)
0.1 3.5 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.1 0.6 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.1 0.7 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091) negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1 0.5 GO:0032472 Golgi calcium ion transport(GO:0032472)
0.1 4.9 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.1 0.3 GO:0050975 sensory perception of touch(GO:0050975)
0.1 0.5 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.1 0.2 GO:0051466 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) positive regulation of corticotropin-releasing hormone secretion(GO:0051466)
0.1 1.1 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.1 0.3 GO:0035977 protein deglycosylation involved in glycoprotein catabolic process(GO:0035977) protein demannosylation(GO:0036507) protein alpha-1,2-demannosylation(GO:0036508) glycoprotein ERAD pathway(GO:0097466) mannose trimming involved in glycoprotein ERAD pathway(GO:1904382) response to glycoprotein(GO:1904587)
0.0 0.5 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 2.1 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 1.0 GO:0030033 microvillus assembly(GO:0030033)
0.0 0.8 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.5 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.0 0.5 GO:0099628 receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628)
0.0 1.0 GO:0050872 white fat cell differentiation(GO:0050872)
0.0 0.4 GO:0015074 DNA integration(GO:0015074)
0.0 1.2 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.6 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.8 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.0 0.8 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.2 GO:0003051 angiotensin-mediated drinking behavior(GO:0003051) tachykinin receptor signaling pathway(GO:0007217) operant conditioning(GO:0035106) positive regulation of saliva secretion(GO:0046878)
0.0 0.8 GO:0001553 luteinization(GO:0001553)
0.0 0.8 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 0.2 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.0 0.9 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.3 GO:0034393 positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.0 1.3 GO:0060292 long term synaptic depression(GO:0060292)
0.0 2.2 GO:0030838 positive regulation of actin filament polymerization(GO:0030838)
0.0 0.8 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0 0.8 GO:0007131 reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.0 3.1 GO:0060048 cardiac muscle contraction(GO:0060048)
0.0 0.7 GO:0021591 ventricular system development(GO:0021591)
0.0 0.7 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.4 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.6 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 1.1 GO:0007173 epidermal growth factor receptor signaling pathway(GO:0007173)
0.0 0.5 GO:0021983 pituitary gland development(GO:0021983)
0.0 0.2 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.5 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
1.1 3.4 GO:0034679 integrin alpha9-beta1 complex(GO:0034679)
0.4 1.5 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.3 1.8 GO:0005663 DNA replication factor C complex(GO:0005663)
0.3 2.0 GO:0005638 lamin filament(GO:0005638)
0.2 0.7 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.2 1.2 GO:0001740 Barr body(GO:0001740)
0.1 1.6 GO:0005688 U6 snRNP(GO:0005688)
0.1 1.3 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.1 0.9 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 7.9 GO:0005657 replication fork(GO:0005657)
0.1 2.7 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 0.8 GO:0097427 microtubule bundle(GO:0097427)
0.1 0.5 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.1 2.3 GO:0005859 muscle myosin complex(GO:0005859) myosin filament(GO:0032982)
0.1 0.6 GO:0071438 invadopodium membrane(GO:0071438)
0.1 4.7 GO:0016459 myosin complex(GO:0016459)
0.1 0.6 GO:0001739 sex chromatin(GO:0001739)
0.1 0.2 GO:0097059 CRLF-CLCF1 complex(GO:0097058) CNTFR-CLCF1 complex(GO:0097059)
0.1 1.1 GO:0035253 ciliary rootlet(GO:0035253)
0.0 2.0 GO:0032590 dendrite membrane(GO:0032590)
0.0 2.7 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.2 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.0 0.6 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.1 GO:0034684 integrin alphav-beta5 complex(GO:0034684) integrin alphav-beta6 complex(GO:0034685)
0.0 0.2 GO:0097422 tubular endosome(GO:0097422)
0.0 0.6 GO:0000178 exosome (RNase complex)(GO:0000178)
0.0 2.6 GO:0030175 filopodium(GO:0030175)
0.0 17.6 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.5 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.3 GO:0042581 specific granule(GO:0042581)
0.0 1.0 GO:0016235 aggresome(GO:0016235)
0.0 1.2 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 1.2 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 6.3 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.6 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 7.8 GO:0005774 vacuolar membrane(GO:0005774)
0.0 1.8 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.4 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.7 GO:0048786 presynaptic active zone(GO:0048786)
0.0 1.4 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.8 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 1.4 GO:0005884 actin filament(GO:0005884)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 6.4 GO:0033680 ATP-dependent DNA/RNA helicase activity(GO:0033680)
2.0 6.0 GO:0005302 L-tyrosine transmembrane transporter activity(GO:0005302)
1.2 7.0 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
1.1 9.2 GO:0035662 Toll-like receptor 4 binding(GO:0035662) RAGE receptor binding(GO:0050786)
0.9 3.5 GO:0050436 microfibril binding(GO:0050436)
0.7 3.5 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.6 1.3 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.5 2.1 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.3 1.6 GO:0030621 U4 snRNA binding(GO:0030621)
0.3 2.4 GO:0005344 oxygen transporter activity(GO:0005344)
0.3 4.9 GO:0045499 chemorepellent activity(GO:0045499)
0.3 6.9 GO:0030553 cGMP binding(GO:0030553)
0.3 5.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.2 1.3 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.2 0.4 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116)
0.2 1.4 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.2 1.3 GO:0030284 estrogen receptor activity(GO:0030284)
0.2 2.0 GO:0019992 diacylglycerol binding(GO:0019992)
0.2 2.7 GO:0004016 adenylate cyclase activity(GO:0004016)
0.2 1.8 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.2 2.1 GO:0005522 profilin binding(GO:0005522)
0.2 1.4 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.1 1.0 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 1.5 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 0.6 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.1 0.6 GO:0044020 protein-arginine omega-N monomethyltransferase activity(GO:0035241) histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.1 4.1 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 2.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.6 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 0.3 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 3.0 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 2.4 GO:0001968 fibronectin binding(GO:0001968)
0.1 0.8 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.1 1.1 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 0.5 GO:0031812 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.1 0.3 GO:0008390 testosterone 16-alpha-hydroxylase activity(GO:0008390)
0.1 0.9 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 0.2 GO:0004995 tachykinin receptor activity(GO:0004995)
0.1 0.6 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.1 2.0 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 6.3 GO:0005179 hormone activity(GO:0005179)
0.1 0.8 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 1.9 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.6 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.7 GO:0002162 dystroglycan binding(GO:0002162)
0.0 3.1 GO:0005518 collagen binding(GO:0005518)
0.0 0.8 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.7 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.6 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 4.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 1.9 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 1.9 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.3 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.2 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 1.5 GO:0070063 RNA polymerase binding(GO:0070063)
0.0 1.0 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.2 GO:0034452 dynactin binding(GO:0034452)
0.0 0.5 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 1.2 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.5 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.5 GO:0042923 neuropeptide binding(GO:0042923)
0.0 1.0 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.9 GO:0030332 cyclin binding(GO:0030332)
0.0 0.9 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 3.4 GO:0003774 motor activity(GO:0003774)
0.0 0.1 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.0 1.4 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 1.4 GO:0017022 myosin binding(GO:0017022)
0.0 0.5 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.9 GO:0019894 kinesin binding(GO:0019894)
0.0 0.1 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 1.7 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.1 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.0 1.0 GO:0046332 SMAD binding(GO:0046332)
0.0 0.8 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.2 GO:0022841 potassium ion leak channel activity(GO:0022841)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 10.4 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.2 5.5 PID CONE PATHWAY Visual signal transduction: Cones
0.1 2.7 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 3.5 PID S1P S1P1 PATHWAY S1P1 pathway
0.1 1.9 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 2.1 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 7.0 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 1.3 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.1 7.8 PID TELOMERASE PATHWAY Regulation of Telomerase
0.1 3.1 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 4.1 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.1 1.8 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 0.9 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 3.4 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 1.3 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 1.3 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 3.6 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 2.0 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 1.5 PID PLK1 PATHWAY PLK1 signaling events
0.0 1.5 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.5 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.5 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 1.0 PID AP1 PATHWAY AP-1 transcription factor network
0.0 4.4 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.6 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.8 PID LKB1 PATHWAY LKB1 signaling events
0.0 1.3 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.6 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.7 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 2.6 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.6 PID IL4 2PATHWAY IL4-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.7 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.2 0.7 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.2 2.1 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.2 3.4 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.2 2.7 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.2 6.3 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 6.0 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 1.7 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 0.9 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.1 5.3 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.1 1.5 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 3.1 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 5.4 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.1 1.0 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 1.3 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 1.1 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.9 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 2.0 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.6 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.9 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.3 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.7 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 5.0 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.2 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 2.1 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF
0.0 1.3 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 1.5 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 1.3 REACTOME MYD88 MAL CASCADE INITIATED ON PLASMA MEMBRANE Genes involved in MyD88:Mal cascade initiated on plasma membrane
0.0 0.2 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.7 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.5 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell