avrg: GSE58827: Dynamics of the Mouse Liver
Gene Symbol | Gene ID | Gene Info |
---|---|---|
Foxa2
|
ENSMUSG00000037025.5 | forkhead box A2 |
Foxa1
|
ENSMUSG00000035451.6 | forkhead box A1 |
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Foxa2 | mm10_v2_chr2_-_148046896_148046991 | 0.68 | 4.1e-06 | Click! |
Foxa1 | mm10_v2_chr12_-_57546121_57546141 | 0.33 | 5.2e-02 | Click! |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
3.6 | 25.5 | GO:0060455 | negative regulation of gastric acid secretion(GO:0060455) |
3.3 | 13.3 | GO:0010901 | regulation of very-low-density lipoprotein particle remodeling(GO:0010901) |
2.9 | 20.0 | GO:0035948 | positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) |
2.1 | 16.7 | GO:0097646 | calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647) |
1.2 | 6.2 | GO:1904253 | positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253) |
1.2 | 7.1 | GO:0038161 | prolactin signaling pathway(GO:0038161) |
1.2 | 4.6 | GO:0010248 | establishment or maintenance of transmembrane electrochemical gradient(GO:0010248) |
1.1 | 5.6 | GO:0051919 | positive regulation of fibrinolysis(GO:0051919) |
1.1 | 4.4 | GO:0009441 | glycolate metabolic process(GO:0009441) |
1.0 | 3.0 | GO:0070104 | negative regulation of interleukin-6-mediated signaling pathway(GO:0070104) |
0.9 | 17.4 | GO:0001833 | inner cell mass cell proliferation(GO:0001833) |
0.8 | 4.8 | GO:0050847 | progesterone receptor signaling pathway(GO:0050847) |
0.7 | 3.5 | GO:0002760 | positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803) |
0.7 | 3.4 | GO:0042536 | negative regulation of tumor necrosis factor biosynthetic process(GO:0042536) |
0.6 | 1.9 | GO:0045643 | regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645) |
0.6 | 1.7 | GO:0021529 | spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) |
0.6 | 1.7 | GO:0061402 | positive regulation of transcription from RNA polymerase II promoter in response to acidic pH(GO:0061402) regulation of glutamine transport(GO:2000485) |
0.6 | 2.3 | GO:0015855 | nucleobase transport(GO:0015851) pyrimidine nucleobase transport(GO:0015855) |
0.5 | 1.6 | GO:2001200 | positive regulation of dendritic cell differentiation(GO:2001200) |
0.5 | 4.2 | GO:0033564 | anterior/posterior axon guidance(GO:0033564) |
0.5 | 2.6 | GO:2000680 | regulation of rubidium ion transport(GO:2000680) |
0.5 | 4.6 | GO:0008228 | opsonization(GO:0008228) |
0.5 | 2.4 | GO:1901509 | regulation of endothelial tube morphogenesis(GO:1901509) |
0.5 | 2.3 | GO:0015886 | heme transport(GO:0015886) |
0.5 | 1.4 | GO:0015920 | lipopolysaccharide transport(GO:0015920) |
0.4 | 1.2 | GO:0097155 | fasciculation of sensory neuron axon(GO:0097155) |
0.4 | 2.2 | GO:0050747 | positive regulation of lipoprotein metabolic process(GO:0050747) |
0.4 | 1.8 | GO:0006207 | 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856) |
0.4 | 1.4 | GO:2000182 | regulation of progesterone biosynthetic process(GO:2000182) |
0.3 | 2.0 | GO:0036438 | maintenance of lens transparency(GO:0036438) |
0.3 | 4.3 | GO:1901898 | negative regulation of relaxation of cardiac muscle(GO:1901898) |
0.3 | 9.3 | GO:0017144 | drug metabolic process(GO:0017144) |
0.3 | 4.5 | GO:0046884 | follicle-stimulating hormone secretion(GO:0046884) |
0.3 | 2.5 | GO:0038028 | insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) |
0.3 | 0.9 | GO:1904457 | positive regulation of neuronal action potential(GO:1904457) |
0.3 | 2.5 | GO:0035887 | aortic smooth muscle cell differentiation(GO:0035887) |
0.3 | 7.9 | GO:0046688 | response to copper ion(GO:0046688) |
0.3 | 0.8 | GO:2000328 | regulation of T-helper 17 cell lineage commitment(GO:2000328) |
0.3 | 2.3 | GO:0031179 | peptide modification(GO:0031179) |
0.2 | 0.5 | GO:0038086 | VEGF-activated platelet-derived growth factor receptor signaling pathway(GO:0038086) positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway(GO:0038091) |
0.2 | 0.7 | GO:0002276 | basophil activation involved in immune response(GO:0002276) |
0.2 | 1.2 | GO:0045994 | regulation of translational initiation by iron(GO:0006447) positive regulation of translational initiation by iron(GO:0045994) |
0.2 | 0.6 | GO:0002305 | gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305) |
0.2 | 2.5 | GO:0019800 | peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800) |
0.2 | 0.6 | GO:1904849 | positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546) |
0.2 | 0.6 | GO:1904868 | signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434) telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884) |
0.2 | 3.2 | GO:0042048 | olfactory behavior(GO:0042048) |
0.2 | 1.2 | GO:1904075 | regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075) |
0.2 | 3.5 | GO:0042359 | vitamin D metabolic process(GO:0042359) |
0.2 | 4.6 | GO:0015721 | bile acid and bile salt transport(GO:0015721) |
0.2 | 2.9 | GO:0015874 | norepinephrine transport(GO:0015874) |
0.2 | 0.7 | GO:1990401 | embryonic lung development(GO:1990401) |
0.2 | 1.5 | GO:0006390 | transcription from mitochondrial promoter(GO:0006390) |
0.2 | 0.7 | GO:0015712 | hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760) |
0.2 | 1.4 | GO:0006689 | ganglioside catabolic process(GO:0006689) oligosaccharide catabolic process(GO:0009313) |
0.2 | 0.5 | GO:1902524 | positive regulation of protein K48-linked ubiquitination(GO:1902524) |
0.2 | 2.4 | GO:0060346 | bone trabecula formation(GO:0060346) |
0.2 | 1.0 | GO:0003199 | endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199) |
0.2 | 1.0 | GO:0060023 | soft palate development(GO:0060023) |
0.2 | 4.0 | GO:0030502 | negative regulation of bone mineralization(GO:0030502) |
0.2 | 1.2 | GO:0006003 | fructose 2,6-bisphosphate metabolic process(GO:0006003) |
0.2 | 1.0 | GO:1901894 | regulation of calcium-transporting ATPase activity(GO:1901894) |
0.2 | 0.5 | GO:0010159 | specification of organ position(GO:0010159) |
0.2 | 1.9 | GO:0061302 | smooth muscle cell-matrix adhesion(GO:0061302) |
0.2 | 1.2 | GO:0035021 | negative regulation of Rac protein signal transduction(GO:0035021) |
0.1 | 0.7 | GO:0098886 | modification of dendritic spine(GO:0098886) |
0.1 | 0.4 | GO:0007521 | muscle cell fate determination(GO:0007521) mammary placode formation(GO:0060596) |
0.1 | 0.9 | GO:0002317 | plasma cell differentiation(GO:0002317) |
0.1 | 0.7 | GO:0006776 | vitamin A metabolic process(GO:0006776) |
0.1 | 0.8 | GO:2000271 | positive regulation of fibroblast apoptotic process(GO:2000271) |
0.1 | 3.2 | GO:0051156 | glucose 6-phosphate metabolic process(GO:0051156) |
0.1 | 1.6 | GO:0051132 | NK T cell activation(GO:0051132) |
0.1 | 0.4 | GO:0097534 | lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535) |
0.1 | 1.4 | GO:0018298 | protein-chromophore linkage(GO:0018298) |
0.1 | 1.5 | GO:0006995 | cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562) |
0.1 | 0.2 | GO:0060741 | prostate gland stromal morphogenesis(GO:0060741) |
0.1 | 1.3 | GO:0015868 | purine ribonucleotide transport(GO:0015868) |
0.1 | 0.5 | GO:1903445 | intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445) |
0.1 | 0.7 | GO:0071630 | nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630) |
0.1 | 0.8 | GO:0051725 | protein de-ADP-ribosylation(GO:0051725) |
0.1 | 0.4 | GO:0046368 | GDP-L-fucose metabolic process(GO:0046368) |
0.1 | 0.8 | GO:1904220 | regulation of serine C-palmitoyltransferase activity(GO:1904220) |
0.1 | 1.6 | GO:0048934 | peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935) |
0.1 | 0.7 | GO:0038044 | transforming growth factor-beta secretion(GO:0038044) |
0.1 | 0.2 | GO:0072107 | regulation of ureteric bud formation(GO:0072106) positive regulation of ureteric bud formation(GO:0072107) |
0.1 | 0.8 | GO:0060665 | regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665) |
0.1 | 0.7 | GO:0051138 | positive regulation of NK T cell differentiation(GO:0051138) |
0.1 | 1.7 | GO:0008090 | retrograde axonal transport(GO:0008090) |
0.1 | 0.9 | GO:0016554 | cytidine to uridine editing(GO:0016554) |
0.1 | 1.3 | GO:0021707 | cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707) |
0.1 | 0.2 | GO:0043988 | histone H3-S28 phosphorylation(GO:0043988) |
0.1 | 0.6 | GO:0006642 | triglyceride mobilization(GO:0006642) |
0.1 | 0.2 | GO:0014834 | skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration(GO:0014834) |
0.1 | 0.3 | GO:2000503 | positive regulation of natural killer cell chemotaxis(GO:2000503) |
0.1 | 0.3 | GO:0046066 | purine deoxyribonucleoside diphosphate metabolic process(GO:0009182) dGDP metabolic process(GO:0046066) |
0.1 | 8.4 | GO:0009166 | nucleotide catabolic process(GO:0009166) |
0.1 | 0.7 | GO:0071493 | cellular response to UV-B(GO:0071493) |
0.1 | 0.4 | GO:0042276 | error-prone translesion synthesis(GO:0042276) |
0.1 | 0.3 | GO:0090472 | dibasic protein processing(GO:0090472) |
0.1 | 1.1 | GO:0060746 | parental behavior(GO:0060746) |
0.1 | 0.6 | GO:0044336 | canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336) |
0.1 | 1.1 | GO:0072189 | ureter development(GO:0072189) |
0.1 | 0.7 | GO:0090557 | establishment of endothelial intestinal barrier(GO:0090557) |
0.1 | 3.1 | GO:0003298 | physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049) |
0.1 | 0.6 | GO:0035372 | protein localization to microtubule(GO:0035372) |
0.1 | 1.4 | GO:0048268 | clathrin coat assembly(GO:0048268) |
0.1 | 0.5 | GO:1903849 | regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849) |
0.1 | 6.9 | GO:0007586 | digestion(GO:0007586) |
0.1 | 2.5 | GO:0003333 | amino acid transmembrane transport(GO:0003333) |
0.1 | 1.5 | GO:0030212 | hyaluronan metabolic process(GO:0030212) |
0.1 | 0.6 | GO:0072378 | blood coagulation, fibrin clot formation(GO:0072378) |
0.1 | 1.6 | GO:0030511 | positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846) |
0.0 | 0.3 | GO:0090091 | positive regulation of extracellular matrix disassembly(GO:0090091) |
0.0 | 2.9 | GO:0046580 | negative regulation of Ras protein signal transduction(GO:0046580) |
0.0 | 0.3 | GO:0038018 | Wnt receptor catabolic process(GO:0038018) |
0.0 | 0.5 | GO:0043116 | negative regulation of vascular permeability(GO:0043116) |
0.0 | 0.6 | GO:0033572 | transferrin transport(GO:0033572) |
0.0 | 0.2 | GO:0061589 | calcium activated phosphatidylserine scrambling(GO:0061589) |
0.0 | 0.4 | GO:0061002 | negative regulation of dendritic spine morphogenesis(GO:0061002) |
0.0 | 0.4 | GO:0001867 | complement activation, lectin pathway(GO:0001867) |
0.0 | 4.2 | GO:0055088 | lipid homeostasis(GO:0055088) |
0.0 | 0.3 | GO:0008063 | Toll signaling pathway(GO:0008063) |
0.0 | 3.5 | GO:0006487 | protein N-linked glycosylation(GO:0006487) |
0.0 | 0.4 | GO:0015747 | urate transport(GO:0015747) |
0.0 | 0.3 | GO:2000807 | regulation of synaptic vesicle clustering(GO:2000807) |
0.0 | 0.4 | GO:2001014 | regulation of skeletal muscle cell differentiation(GO:2001014) |
0.0 | 0.5 | GO:0045792 | negative regulation of cell size(GO:0045792) |
0.0 | 0.7 | GO:0031069 | hair follicle morphogenesis(GO:0031069) |
0.0 | 0.6 | GO:0045109 | intermediate filament organization(GO:0045109) |
0.0 | 1.6 | GO:0006940 | regulation of smooth muscle contraction(GO:0006940) |
0.0 | 1.7 | GO:0045600 | positive regulation of fat cell differentiation(GO:0045600) |
0.0 | 0.5 | GO:2000480 | negative regulation of cAMP-dependent protein kinase activity(GO:2000480) |
0.0 | 1.0 | GO:0006182 | cGMP biosynthetic process(GO:0006182) |
0.0 | 0.4 | GO:0003215 | cardiac right ventricle morphogenesis(GO:0003215) |
0.0 | 0.9 | GO:0001958 | endochondral ossification(GO:0001958) replacement ossification(GO:0036075) |
0.0 | 1.1 | GO:0045851 | pH reduction(GO:0045851) |
0.0 | 0.7 | GO:0060706 | cell differentiation involved in embryonic placenta development(GO:0060706) |
0.0 | 40.3 | GO:0006508 | proteolysis(GO:0006508) |
0.0 | 2.4 | GO:0035725 | sodium ion transmembrane transport(GO:0035725) |
0.0 | 0.3 | GO:0046549 | retinal cone cell development(GO:0046549) |
0.0 | 2.8 | GO:0050731 | positive regulation of peptidyl-tyrosine phosphorylation(GO:0050731) |
0.0 | 0.8 | GO:0071526 | semaphorin-plexin signaling pathway(GO:0071526) |
0.0 | 0.7 | GO:0006687 | glycosphingolipid metabolic process(GO:0006687) |
0.0 | 0.2 | GO:0006309 | apoptotic DNA fragmentation(GO:0006309) |
0.0 | 0.1 | GO:0042663 | regulation of endodermal cell fate specification(GO:0042663) |
0.0 | 0.8 | GO:0051453 | regulation of intracellular pH(GO:0051453) |
0.0 | 0.1 | GO:0016332 | establishment or maintenance of polarity of embryonic epithelium(GO:0016332) |
0.0 | 0.2 | GO:0003254 | regulation of membrane depolarization(GO:0003254) |
0.0 | 0.3 | GO:0045793 | positive regulation of cell size(GO:0045793) |
0.0 | 0.2 | GO:0001778 | plasma membrane repair(GO:0001778) |
0.0 | 0.2 | GO:0052695 | cellular glucuronidation(GO:0052695) |
0.0 | 0.1 | GO:0003383 | apical constriction(GO:0003383) |
0.0 | 0.3 | GO:0032467 | positive regulation of cytokinesis(GO:0032467) |
0.0 | 2.6 | GO:0043434 | response to peptide hormone(GO:0043434) |
0.0 | 0.2 | GO:1904355 | positive regulation of telomere capping(GO:1904355) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.5 | 17.4 | GO:0030670 | phagocytic vesicle membrane(GO:0030670) |
1.1 | 8.9 | GO:0045098 | type III intermediate filament(GO:0045098) |
1.0 | 3.0 | GO:0005900 | oncostatin-M receptor complex(GO:0005900) |
0.9 | 3.8 | GO:0044218 | other organism cell membrane(GO:0044218) other organism membrane(GO:0044279) |
0.6 | 13.9 | GO:0042627 | chylomicron(GO:0042627) |
0.5 | 2.2 | GO:0097487 | multivesicular body, internal vesicle(GO:0097487) |
0.4 | 1.2 | GO:0043540 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540) |
0.3 | 1.9 | GO:0048237 | rough endoplasmic reticulum lumen(GO:0048237) |
0.3 | 1.7 | GO:0031673 | H zone(GO:0031673) |
0.2 | 0.7 | GO:0034685 | integrin alphav-beta6 complex(GO:0034685) |
0.2 | 0.7 | GO:0070557 | PCNA-p21 complex(GO:0070557) |
0.2 | 1.6 | GO:0030478 | actin cap(GO:0030478) |
0.2 | 0.9 | GO:0044316 | cone cell pedicle(GO:0044316) |
0.2 | 4.3 | GO:0000930 | gamma-tubulin complex(GO:0000930) |
0.2 | 2.9 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
0.2 | 3.6 | GO:0005922 | connexon complex(GO:0005922) |
0.2 | 5.3 | GO:0005771 | multivesicular body(GO:0005771) |
0.1 | 1.2 | GO:0035867 | alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867) |
0.1 | 1.6 | GO:0046581 | intercellular canaliculus(GO:0046581) |
0.1 | 20.7 | GO:0072562 | blood microparticle(GO:0072562) |
0.1 | 2.5 | GO:0071564 | npBAF complex(GO:0071564) |
0.1 | 0.7 | GO:0097444 | spine apparatus(GO:0097444) |
0.1 | 167.3 | GO:0005615 | extracellular space(GO:0005615) |
0.1 | 0.7 | GO:1990357 | terminal web(GO:1990357) |
0.1 | 0.7 | GO:0017059 | serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211) |
0.1 | 0.2 | GO:0016939 | kinesin II complex(GO:0016939) |
0.1 | 0.4 | GO:0016035 | zeta DNA polymerase complex(GO:0016035) |
0.1 | 1.5 | GO:0000421 | autophagosome membrane(GO:0000421) |
0.1 | 3.2 | GO:0042645 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
0.1 | 3.3 | GO:0005604 | basement membrane(GO:0005604) |
0.1 | 1.3 | GO:0016471 | vacuolar proton-transporting V-type ATPase complex(GO:0016471) |
0.0 | 4.8 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
0.0 | 1.8 | GO:0005581 | collagen trimer(GO:0005581) |
0.0 | 13.9 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
0.0 | 0.5 | GO:0031931 | TORC1 complex(GO:0031931) |
0.0 | 1.0 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
0.0 | 1.0 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
0.0 | 2.2 | GO:0031526 | brush border membrane(GO:0031526) |
0.0 | 0.2 | GO:0000308 | cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308) |
0.0 | 5.5 | GO:0031227 | intrinsic component of endoplasmic reticulum membrane(GO:0031227) |
0.0 | 0.4 | GO:0032580 | Golgi cisterna membrane(GO:0032580) |
0.0 | 0.2 | GO:0001652 | granular component(GO:0001652) |
0.0 | 0.2 | GO:0035032 | phosphatidylinositol 3-kinase complex, class III(GO:0035032) |
0.0 | 1.0 | GO:0005719 | nuclear euchromatin(GO:0005719) |
0.0 | 3.2 | GO:0031234 | extrinsic component of cytoplasmic side of plasma membrane(GO:0031234) |
0.0 | 4.0 | GO:0042579 | peroxisome(GO:0005777) microbody(GO:0042579) |
0.0 | 0.3 | GO:0012510 | trans-Golgi network transport vesicle membrane(GO:0012510) |
0.0 | 1.2 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
0.0 | 0.1 | GO:0043219 | lateral loop(GO:0043219) |
0.0 | 0.7 | GO:0005902 | microvillus(GO:0005902) |
0.0 | 1.5 | GO:0031225 | anchored component of membrane(GO:0031225) |
0.0 | 0.6 | GO:1990391 | DNA repair complex(GO:1990391) |
0.0 | 0.9 | GO:0005811 | lipid particle(GO:0005811) |
0.0 | 0.3 | GO:0045178 | basal part of cell(GO:0045178) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
10.3 | 71.8 | GO:0004556 | alpha-amylase activity(GO:0004556) |
2.5 | 7.5 | GO:0005333 | norepinephrine transmembrane transporter activity(GO:0005333) |
1.9 | 24.7 | GO:0045236 | CXCR chemokine receptor binding(GO:0045236) |
1.8 | 8.9 | GO:0004850 | uridine phosphorylase activity(GO:0004850) |
1.8 | 12.4 | GO:0060230 | lipoprotein lipase activator activity(GO:0060230) |
1.7 | 54.4 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
1.4 | 7.1 | GO:0004925 | prolactin receptor activity(GO:0004925) |
1.2 | 3.5 | GO:1902271 | D3 vitamins binding(GO:1902271) |
1.1 | 4.4 | GO:0016899 | oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899) |
1.1 | 3.2 | GO:0004346 | glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309) |
1.0 | 3.0 | GO:0004923 | interleukin-6 receptor activity(GO:0004915) leukemia inhibitory factor receptor activity(GO:0004923) interleukin-6 binding(GO:0019981) |
0.8 | 4.0 | GO:0030292 | protein tyrosine kinase inhibitor activity(GO:0030292) |
0.7 | 7.2 | GO:0004322 | ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724) |
0.6 | 1.8 | GO:0004088 | carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088) |
0.6 | 2.3 | GO:0015232 | heme transporter activity(GO:0015232) |
0.6 | 2.3 | GO:0016842 | amidine-lyase activity(GO:0016842) |
0.6 | 4.0 | GO:0008508 | bile acid:sodium symporter activity(GO:0008508) |
0.6 | 1.7 | GO:0015182 | L-asparagine transmembrane transporter activity(GO:0015182) |
0.5 | 2.0 | GO:0008109 | N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109) |
0.5 | 3.9 | GO:0015379 | potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820) |
0.5 | 2.3 | GO:0015205 | purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205) glycerol channel activity(GO:0015254) |
0.4 | 2.7 | GO:0047023 | androsterone dehydrogenase activity(GO:0047023) |
0.4 | 19.8 | GO:0005044 | scavenger receptor activity(GO:0005044) |
0.4 | 1.5 | GO:0000179 | rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179) |
0.3 | 1.0 | GO:0005118 | sevenless binding(GO:0005118) |
0.3 | 1.0 | GO:0034191 | apolipoprotein A-I receptor binding(GO:0034191) |
0.3 | 38.1 | GO:0005179 | hormone activity(GO:0005179) |
0.3 | 1.4 | GO:0052796 | exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796) |
0.2 | 0.7 | GO:0035651 | AP-3 adaptor complex binding(GO:0035651) |
0.2 | 3.1 | GO:1990405 | protein antigen binding(GO:1990405) |
0.2 | 0.7 | GO:0019912 | cyclin-dependent protein kinase activating kinase activity(GO:0019912) |
0.2 | 1.4 | GO:0071723 | lipoteichoic acid binding(GO:0070891) lipopeptide binding(GO:0071723) |
0.2 | 7.7 | GO:0016712 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712) |
0.2 | 1.6 | GO:0005534 | galactose binding(GO:0005534) |
0.2 | 0.9 | GO:0032422 | purine-rich negative regulatory element binding(GO:0032422) |
0.2 | 0.6 | GO:0004677 | DNA-dependent protein kinase activity(GO:0004677) |
0.2 | 2.2 | GO:0008429 | phosphatidylethanolamine binding(GO:0008429) |
0.2 | 1.2 | GO:0070644 | vitamin D response element binding(GO:0070644) |
0.2 | 2.4 | GO:0005436 | sodium:phosphate symporter activity(GO:0005436) |
0.2 | 0.7 | GO:0015315 | hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513) |
0.2 | 1.4 | GO:0032051 | clathrin light chain binding(GO:0032051) |
0.2 | 6.2 | GO:0016709 | steroid hydroxylase activity(GO:0008395) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709) |
0.2 | 2.2 | GO:0044548 | S100 protein binding(GO:0044548) |
0.1 | 0.7 | GO:0004758 | serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454) |
0.1 | 2.2 | GO:0001871 | pattern binding(GO:0001871) polysaccharide binding(GO:0030247) |
0.1 | 1.2 | GO:0070095 | fructose-6-phosphate binding(GO:0070095) |
0.1 | 2.8 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
0.1 | 1.2 | GO:0005004 | GPI-linked ephrin receptor activity(GO:0005004) |
0.1 | 1.2 | GO:0030550 | acetylcholine receptor inhibitor activity(GO:0030550) |
0.1 | 3.5 | GO:0004190 | aspartic-type endopeptidase activity(GO:0004190) |
0.1 | 0.7 | GO:0008970 | phosphatidylcholine 1-acylhydrolase activity(GO:0008970) |
0.1 | 0.6 | GO:0005105 | type 1 fibroblast growth factor receptor binding(GO:0005105) |
0.1 | 4.3 | GO:0004115 | 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) |
0.1 | 0.5 | GO:0038085 | vascular endothelial growth factor binding(GO:0038085) |
0.1 | 1.9 | GO:0055106 | ubiquitin-protein transferase regulator activity(GO:0055106) |
0.1 | 0.3 | GO:0031726 | CCR1 chemokine receptor binding(GO:0031726) |
0.1 | 0.3 | GO:0050145 | nucleoside phosphate kinase activity(GO:0050145) |
0.1 | 1.5 | GO:0030957 | Tat protein binding(GO:0030957) |
0.1 | 1.5 | GO:0004806 | triglyceride lipase activity(GO:0004806) |
0.1 | 1.7 | GO:0001530 | lipopolysaccharide binding(GO:0001530) |
0.1 | 1.4 | GO:0019865 | immunoglobulin binding(GO:0019865) |
0.1 | 1.3 | GO:0005243 | gap junction channel activity(GO:0005243) |
0.1 | 0.6 | GO:0035473 | lipase binding(GO:0035473) |
0.1 | 1.0 | GO:0015643 | toxic substance binding(GO:0015643) |
0.1 | 0.5 | GO:0008131 | primary amine oxidase activity(GO:0008131) |
0.1 | 0.4 | GO:0031404 | chloride ion binding(GO:0031404) |
0.1 | 0.5 | GO:0071253 | connexin binding(GO:0071253) |
0.1 | 11.9 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
0.1 | 2.4 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
0.0 | 0.7 | GO:0019841 | retinol binding(GO:0019841) |
0.0 | 0.7 | GO:0001206 | transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206) |
0.0 | 0.6 | GO:0017154 | semaphorin receptor activity(GO:0017154) |
0.0 | 0.5 | GO:0015386 | potassium:proton antiporter activity(GO:0015386) |
0.0 | 0.2 | GO:0004531 | deoxyribonuclease II activity(GO:0004531) |
0.0 | 0.5 | GO:0070097 | delta-catenin binding(GO:0070097) |
0.0 | 0.3 | GO:0038062 | protein tyrosine kinase collagen receptor activity(GO:0038062) |
0.0 | 1.4 | GO:0043014 | alpha-tubulin binding(GO:0043014) |
0.0 | 0.8 | GO:0008510 | sodium:bicarbonate symporter activity(GO:0008510) |
0.0 | 2.1 | GO:0050840 | extracellular matrix binding(GO:0050840) |
0.0 | 0.4 | GO:0098599 | palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599) |
0.0 | 5.5 | GO:0002020 | protease binding(GO:0002020) |
0.0 | 2.3 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
0.0 | 0.4 | GO:0008417 | fucosyltransferase activity(GO:0008417) |
0.0 | 0.5 | GO:0004862 | cAMP-dependent protein kinase inhibitor activity(GO:0004862) |
0.0 | 0.4 | GO:0019869 | chloride channel inhibitor activity(GO:0019869) |
0.0 | 1.2 | GO:0015020 | glucuronosyltransferase activity(GO:0015020) |
0.0 | 0.9 | GO:0030552 | cAMP binding(GO:0030552) |
0.0 | 1.9 | GO:0098531 | RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531) |
0.0 | 1.5 | GO:0000980 | RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980) |
0.0 | 0.3 | GO:0004016 | adenylate cyclase activity(GO:0004016) |
0.0 | 0.5 | GO:0071837 | HMG box domain binding(GO:0071837) |
0.0 | 0.3 | GO:0004089 | carbonate dehydratase activity(GO:0004089) |
0.0 | 0.6 | GO:0070888 | E-box binding(GO:0070888) |
0.0 | 1.3 | GO:0015078 | hydrogen ion transmembrane transporter activity(GO:0015078) |
0.0 | 0.2 | GO:0005229 | intracellular calcium activated chloride channel activity(GO:0005229) |
0.0 | 0.1 | GO:0015193 | L-proline transmembrane transporter activity(GO:0015193) |
0.0 | 0.3 | GO:0070273 | phosphatidylinositol-4-phosphate binding(GO:0070273) |
0.0 | 4.0 | GO:0005096 | GTPase activator activity(GO:0005096) |
0.0 | 0.5 | GO:0005109 | frizzled binding(GO:0005109) |
0.0 | 0.9 | GO:0004860 | protein kinase inhibitor activity(GO:0004860) |
0.0 | 1.9 | GO:0017124 | SH3 domain binding(GO:0017124) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 30.9 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
0.1 | 3.0 | PID IL27 PATHWAY | IL27-mediated signaling events |
0.1 | 1.2 | PID EPHA FWDPATHWAY | EPHA forward signaling |
0.1 | 23.0 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
0.1 | 6.9 | PID PTP1B PATHWAY | Signaling events mediated by PTP1B |
0.1 | 7.4 | PID AJDISS 2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
0.1 | 3.1 | PID UPA UPAR PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
0.1 | 0.7 | SA G2 AND M PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
0.1 | 1.6 | PID INTEGRIN2 PATHWAY | Beta2 integrin cell surface interactions |
0.1 | 0.7 | PID INTEGRIN5 PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
0.1 | 1.4 | PID HDAC CLASSIII PATHWAY | Signaling events mediated by HDAC Class III |
0.1 | 1.6 | PID P38 MK2 PATHWAY | p38 signaling mediated by MAPKAP kinases |
0.1 | 3.0 | PID AR TF PATHWAY | Regulation of Androgen receptor activity |
0.1 | 4.6 | PID REG GR PATHWAY | Glucocorticoid receptor regulatory network |
0.0 | 0.5 | PID PDGFRA PATHWAY | PDGFR-alpha signaling pathway |
0.0 | 4.4 | PID HIF1 TFPATHWAY | HIF-1-alpha transcription factor network |
0.0 | 3.0 | PID AVB3 INTEGRIN PATHWAY | Integrins in angiogenesis |
0.0 | 1.9 | PID FGF PATHWAY | FGF signaling pathway |
0.0 | 0.5 | PID NECTIN PATHWAY | Nectin adhesion pathway |
0.0 | 0.5 | PID EPHRINB REV PATHWAY | Ephrin B reverse signaling |
0.0 | 0.7 | PID WNT CANONICAL PATHWAY | Canonical Wnt signaling pathway |
0.0 | 0.7 | PID ECADHERIN NASCENT AJ PATHWAY | E-cadherin signaling in the nascent adherens junction |
0.0 | 0.6 | PID BMP PATHWAY | BMP receptor signaling |
0.0 | 1.4 | PID TRKR PATHWAY | Neurotrophic factor-mediated Trk receptor signaling |
0.0 | 0.7 | PID CONE PATHWAY | Visual signal transduction: Cones |
0.0 | 0.6 | PID P38 MKK3 6PATHWAY | p38 MAPK signaling pathway |
0.0 | 0.5 | PID IL6 7 PATHWAY | IL6-mediated signaling events |
0.0 | 0.2 | PID MAPK TRK PATHWAY | Trk receptor signaling mediated by the MAPK pathway |
0.0 | 0.2 | PID SYNDECAN 4 PATHWAY | Syndecan-4-mediated signaling events |
0.0 | 2.0 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.6 | 7.7 | REACTOME XENOBIOTICS | Genes involved in Xenobiotics |
1.1 | 19.6 | REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN | Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin |
0.6 | 4.6 | REACTOME HORMONE LIGAND BINDING RECEPTORS | Genes involved in Hormone ligand-binding receptors |
0.6 | 7.5 | REACTOME ABACAVIR TRANSPORT AND METABOLISM | Genes involved in Abacavir transport and metabolism |
0.5 | 13.9 | REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
0.5 | 8.9 | REACTOME PYRIMIDINE CATABOLISM | Genes involved in Pyrimidine catabolism |
0.5 | 17.5 | REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS | Genes involved in Regulation of gene expression in beta cells |
0.5 | 6.2 | REACTOME ENDOGENOUS STEROLS | Genes involved in Endogenous sterols |
0.4 | 4.0 | REACTOME RECYCLING OF BILE ACIDS AND SALTS | Genes involved in Recycling of bile acids and salts |
0.4 | 7.1 | REACTOME PROLACTIN RECEPTOR SIGNALING | Genes involved in Prolactin receptor signaling |
0.3 | 4.2 | REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING | Genes involved in Role of second messengers in netrin-1 signaling |
0.3 | 3.0 | REACTOME IL 6 SIGNALING | Genes involved in Interleukin-6 signaling |
0.3 | 5.6 | REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
0.2 | 4.5 | REACTOME GAP JUNCTION ASSEMBLY | Genes involved in Gap junction assembly |
0.2 | 2.3 | REACTOME PASSIVE TRANSPORT BY AQUAPORINS | Genes involved in Passive Transport by Aquaporins |
0.2 | 8.5 | REACTOME IRON UPTAKE AND TRANSPORT | Genes involved in Iron uptake and transport |
0.2 | 2.8 | REACTOME SIGNALING BY FGFR3 MUTANTS | Genes involved in Signaling by FGFR3 mutants |
0.1 | 3.8 | REACTOME STEROID HORMONES | Genes involved in Steroid hormones |
0.1 | 2.5 | REACTOME INTRINSIC PATHWAY | Genes involved in Intrinsic Pathway |
0.1 | 0.7 | REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D | Genes involved in Metabolism of steroid hormones and vitamins A and D |
0.1 | 4.0 | REACTOME DARPP 32 EVENTS | Genes involved in DARPP-32 events |
0.1 | 4.1 | REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
0.1 | 4.0 | REACTOME GLUCOSE TRANSPORT | Genes involved in Glucose transport |
0.1 | 0.8 | REACTOME IL 7 SIGNALING | Genes involved in Interleukin-7 signaling |
0.1 | 1.1 | REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL | Genes involved in AKT phosphorylates targets in the cytosol |
0.1 | 2.0 | REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA | Genes involved in Circadian Repression of Expression by REV-ERBA |
0.1 | 0.6 | REACTOME G2 M DNA DAMAGE CHECKPOINT | Genes involved in G2/M DNA damage checkpoint |
0.1 | 0.4 | REACTOME CREATION OF C4 AND C2 ACTIVATORS | Genes involved in Creation of C4 and C2 activators |
0.0 | 2.8 | REACTOME NCAM1 INTERACTIONS | Genes involved in NCAM1 interactions |
0.0 | 0.6 | REACTOME COMMON PATHWAY | Genes involved in Common Pathway |
0.0 | 0.6 | REACTOME P2Y RECEPTORS | Genes involved in P2Y receptors |
0.0 | 0.7 | REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS | Genes involved in Apoptotic cleavage of cell adhesion proteins |
0.0 | 0.4 | REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT | Genes involved in Organic cation/anion/zwitterion transport |
0.0 | 2.8 | REACTOME INTEGRIN CELL SURFACE INTERACTIONS | Genes involved in Integrin cell surface interactions |
0.0 | 1.4 | REACTOME GLYCOSPHINGOLIPID METABOLISM | Genes involved in Glycosphingolipid metabolism |
0.0 | 1.8 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
0.0 | 0.3 | REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS | Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins |
0.0 | 1.3 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
0.0 | 1.2 | REACTOME GLYCOLYSIS | Genes involved in Glycolysis |
0.0 | 1.6 | REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
0.0 | 2.1 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
0.0 | 5.4 | REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES | Genes involved in Metabolism of amino acids and derivatives |
0.0 | 0.3 | REACTOME GLUCURONIDATION | Genes involved in Glucuronidation |
0.0 | 0.4 | REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI | Genes involved in N-glycan antennae elongation in the medial/trans-Golgi |
0.0 | 0.5 | REACTOME SYNTHESIS OF PC | Genes involved in Synthesis of PC |
0.0 | 1.3 | REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
0.0 | 0.5 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
0.0 | 0.1 | REACTOME ERKS ARE INACTIVATED | Genes involved in ERKs are inactivated |