avrg: GSE58827: Dynamics of the Mouse Liver
Gene Symbol | Gene ID | Gene Info |
---|---|---|
Pou3f2
|
ENSMUSG00000095139.1 | POU domain, class 3, transcription factor 2 |
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Pou3f2 | mm10_v2_chr4_-_22488296_22488366 | 0.28 | 9.6e-02 | Click! |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.9 | 2.7 | GO:0033189 | response to vitamin A(GO:0033189) |
0.6 | 4.0 | GO:0035948 | positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) |
0.4 | 3.6 | GO:0038028 | insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) |
0.4 | 1.7 | GO:0003365 | establishment of cell polarity involved in ameboidal cell migration(GO:0003365) |
0.3 | 1.0 | GO:0010710 | regulation of collagen catabolic process(GO:0010710) negative regulation of extracellular matrix disassembly(GO:0010716) |
0.3 | 1.7 | GO:0014826 | vein smooth muscle contraction(GO:0014826) |
0.3 | 2.1 | GO:0097646 | calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647) |
0.2 | 0.6 | GO:0046832 | RNA import into nucleus(GO:0006404) mRNA export from nucleus in response to heat stress(GO:0031990) negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832) |
0.2 | 0.6 | GO:1902226 | regulation of macrophage colony-stimulating factor signaling pathway(GO:1902226) regulation of response to macrophage colony-stimulating factor(GO:1903969) regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903972) |
0.2 | 0.9 | GO:0042938 | dipeptide transport(GO:0042938) |
0.1 | 0.6 | GO:0015825 | L-serine transport(GO:0015825) |
0.1 | 0.4 | GO:2000328 | regulation of T-helper 17 cell lineage commitment(GO:2000328) |
0.1 | 0.4 | GO:1904023 | regulation of fermentation(GO:0043465) regulation of bone mineralization involved in bone maturation(GO:1900157) regulation of NAD metabolic process(GO:1902688) regulation of glucose catabolic process to lactate via pyruvate(GO:1904023) |
0.1 | 1.1 | GO:0071883 | activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883) |
0.1 | 1.5 | GO:0048752 | semicircular canal morphogenesis(GO:0048752) |
0.1 | 0.4 | GO:0009106 | lipoate metabolic process(GO:0009106) |
0.1 | 4.2 | GO:0019731 | antibacterial humoral response(GO:0019731) |
0.1 | 0.3 | GO:0035709 | memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568) |
0.1 | 0.7 | GO:0031508 | pericentric heterochromatin assembly(GO:0031508) |
0.1 | 1.1 | GO:0010452 | histone H3-K36 methylation(GO:0010452) |
0.1 | 0.3 | GO:0002314 | germinal center B cell differentiation(GO:0002314) |
0.1 | 0.9 | GO:0018095 | protein polyglutamylation(GO:0018095) |
0.1 | 0.7 | GO:0000056 | ribosomal small subunit export from nucleus(GO:0000056) |
0.1 | 0.6 | GO:0044791 | modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791) |
0.1 | 0.3 | GO:2000158 | positive regulation of ubiquitin-specific protease activity(GO:2000158) |
0.1 | 1.2 | GO:0015809 | arginine transport(GO:0015809) |
0.1 | 0.5 | GO:1900747 | negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747) |
0.1 | 8.7 | GO:0007586 | digestion(GO:0007586) |
0.0 | 0.3 | GO:0090520 | sphingolipid mediated signaling pathway(GO:0090520) |
0.0 | 0.7 | GO:0090336 | positive regulation of brown fat cell differentiation(GO:0090336) |
0.0 | 0.1 | GO:0038190 | neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190) |
0.0 | 0.7 | GO:0051574 | positive regulation of histone H3-K9 methylation(GO:0051574) |
0.0 | 0.6 | GO:2000807 | regulation of synaptic vesicle clustering(GO:2000807) |
0.0 | 0.1 | GO:0010643 | cell communication by chemical coupling(GO:0010643) |
0.0 | 0.8 | GO:0006622 | protein targeting to lysosome(GO:0006622) |
0.0 | 0.1 | GO:0036292 | DNA rewinding(GO:0036292) |
0.0 | 0.3 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
0.0 | 0.4 | GO:0016554 | cytidine to uridine editing(GO:0016554) |
0.0 | 0.5 | GO:1902902 | negative regulation of autophagosome assembly(GO:1902902) |
0.0 | 2.0 | GO:1900026 | positive regulation of substrate adhesion-dependent cell spreading(GO:1900026) |
0.0 | 0.5 | GO:0006123 | mitochondrial electron transport, cytochrome c to oxygen(GO:0006123) |
0.0 | 0.7 | GO:0008090 | retrograde axonal transport(GO:0008090) |
0.0 | 0.3 | GO:0048386 | positive regulation of retinoic acid receptor signaling pathway(GO:0048386) |
0.0 | 0.3 | GO:0032534 | regulation of microvillus assembly(GO:0032534) |
0.0 | 0.1 | GO:0018026 | peptidyl-lysine monomethylation(GO:0018026) |
0.0 | 0.9 | GO:0060236 | regulation of mitotic spindle organization(GO:0060236) |
0.0 | 0.8 | GO:0006825 | copper ion transport(GO:0006825) |
0.0 | 1.6 | GO:0050829 | defense response to Gram-negative bacterium(GO:0050829) |
0.0 | 0.6 | GO:0043486 | histone exchange(GO:0043486) |
0.0 | 0.1 | GO:0032468 | cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) manganese ion homeostasis(GO:0055071) |
0.0 | 0.4 | GO:0007183 | SMAD protein complex assembly(GO:0007183) |
0.0 | 0.8 | GO:0046677 | response to antibiotic(GO:0046677) |
0.0 | 0.4 | GO:0050860 | negative regulation of T cell receptor signaling pathway(GO:0050860) |
0.0 | 0.3 | GO:0006027 | glycosaminoglycan catabolic process(GO:0006027) |
0.0 | 0.3 | GO:0016973 | poly(A)+ mRNA export from nucleus(GO:0016973) |
0.0 | 0.7 | GO:0016572 | histone phosphorylation(GO:0016572) |
0.0 | 1.1 | GO:0043113 | receptor clustering(GO:0043113) |
0.0 | 0.5 | GO:0050869 | negative regulation of B cell activation(GO:0050869) |
0.0 | 0.4 | GO:0001953 | negative regulation of cell-matrix adhesion(GO:0001953) |
0.0 | 0.1 | GO:0010994 | regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994) |
0.0 | 0.1 | GO:0042737 | drug catabolic process(GO:0042737) |
0.0 | 0.1 | GO:0090084 | negative regulation of inclusion body assembly(GO:0090084) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 1.0 | GO:0071438 | invadopodium membrane(GO:0071438) |
0.1 | 2.0 | GO:0042581 | specific granule(GO:0042581) |
0.1 | 0.4 | GO:0043159 | acrosomal matrix(GO:0043159) |
0.1 | 0.7 | GO:0031673 | H zone(GO:0031673) |
0.1 | 0.6 | GO:0044615 | nuclear pore nuclear basket(GO:0044615) |
0.1 | 0.7 | GO:0001940 | male pronucleus(GO:0001940) |
0.1 | 0.9 | GO:0072687 | meiotic spindle(GO:0072687) |
0.1 | 0.7 | GO:0005642 | annulate lamellae(GO:0005642) |
0.1 | 0.8 | GO:0044754 | autolysosome(GO:0044754) |
0.0 | 0.9 | GO:0031616 | spindle pole centrosome(GO:0031616) |
0.0 | 0.5 | GO:0060091 | kinocilium(GO:0060091) |
0.0 | 1.7 | GO:0008180 | COP9 signalosome(GO:0008180) |
0.0 | 0.5 | GO:0017119 | Golgi transport complex(GO:0017119) |
0.0 | 0.1 | GO:0031232 | extrinsic component of external side of plasma membrane(GO:0031232) |
0.0 | 0.1 | GO:0099522 | region of cytosol(GO:0099522) postsynaptic cytosol(GO:0099524) |
0.0 | 0.4 | GO:0000506 | glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506) |
0.0 | 0.3 | GO:0061700 | GATOR2 complex(GO:0061700) |
0.0 | 0.7 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
0.0 | 0.5 | GO:0005751 | mitochondrial respiratory chain complex IV(GO:0005751) |
0.0 | 0.3 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
0.0 | 0.7 | GO:0005721 | pericentric heterochromatin(GO:0005721) |
0.0 | 0.4 | GO:0098644 | complex of collagen trimers(GO:0098644) |
0.0 | 0.3 | GO:0097470 | ribbon synapse(GO:0097470) |
0.0 | 0.3 | GO:0000346 | transcription export complex(GO:0000346) |
0.0 | 2.4 | GO:0072562 | blood microparticle(GO:0072562) |
0.0 | 0.2 | GO:0042555 | MCM complex(GO:0042555) |
0.0 | 21.5 | GO:0005615 | extracellular space(GO:0005615) |
0.0 | 1.1 | GO:0030864 | cortical actin cytoskeleton(GO:0030864) |
0.0 | 0.5 | GO:0043034 | costamere(GO:0043034) |
0.0 | 1.2 | GO:0005814 | centriole(GO:0005814) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.6 | 1.7 | GO:0004962 | endothelin receptor activity(GO:0004962) |
0.3 | 1.7 | GO:0043532 | angiostatin binding(GO:0043532) |
0.3 | 2.2 | GO:0004027 | alcohol sulfotransferase activity(GO:0004027) |
0.3 | 0.9 | GO:0042936 | dipeptide transporter activity(GO:0042936) |
0.2 | 0.6 | GO:0005157 | macrophage colony-stimulating factor receptor binding(GO:0005157) |
0.2 | 1.1 | GO:0046975 | histone methyltransferase activity (H3-K36 specific)(GO:0046975) |
0.2 | 1.2 | GO:0015181 | arginine transmembrane transporter activity(GO:0015181) |
0.1 | 0.3 | GO:0035673 | oligopeptide transmembrane transporter activity(GO:0035673) |
0.1 | 1.1 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
0.1 | 0.3 | GO:0023025 | MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030) |
0.1 | 0.9 | GO:0070739 | protein-glutamic acid ligase activity(GO:0070739) |
0.1 | 0.9 | GO:0004322 | ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724) |
0.1 | 3.6 | GO:0005159 | insulin-like growth factor receptor binding(GO:0005159) protein serine/threonine kinase activator activity(GO:0043539) |
0.1 | 1.0 | GO:0008239 | dipeptidyl-peptidase activity(GO:0008239) |
0.1 | 0.3 | GO:0035800 | deubiquitinase activator activity(GO:0035800) |
0.1 | 0.4 | GO:0004738 | pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604) |
0.1 | 0.7 | GO:0005049 | nuclear export signal receptor activity(GO:0005049) |
0.1 | 0.3 | GO:0004974 | leukotriene receptor activity(GO:0004974) |
0.1 | 6.4 | GO:0005179 | hormone activity(GO:0005179) |
0.0 | 0.1 | GO:0043183 | vascular endothelial growth factor receptor 1 binding(GO:0043183) |
0.0 | 9.4 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
0.0 | 0.6 | GO:0015194 | L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889) |
0.0 | 0.3 | GO:0070290 | N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290) |
0.0 | 0.3 | GO:0030267 | hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267) |
0.0 | 0.1 | GO:0070401 | NADP+ binding(GO:0070401) |
0.0 | 0.4 | GO:0017176 | phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176) |
0.0 | 0.3 | GO:1990247 | N6-methyladenosine-containing RNA binding(GO:1990247) |
0.0 | 0.4 | GO:0038191 | neuropilin binding(GO:0038191) |
0.0 | 2.7 | GO:0042562 | hormone binding(GO:0042562) |
0.0 | 1.5 | GO:0070888 | E-box binding(GO:0070888) |
0.0 | 0.1 | GO:0086075 | gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075) |
0.0 | 0.6 | GO:0005487 | nucleocytoplasmic transporter activity(GO:0005487) |
0.0 | 0.4 | GO:0005545 | 1-phosphatidylinositol binding(GO:0005545) |
0.0 | 0.1 | GO:0019834 | phospholipase A2 inhibitor activity(GO:0019834) |
0.0 | 0.1 | GO:0015410 | manganese-transporting ATPase activity(GO:0015410) |
0.0 | 0.3 | GO:0016671 | oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671) |
0.0 | 0.1 | GO:0031812 | G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812) |
0.0 | 0.1 | GO:0004117 | calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101) |
0.0 | 0.7 | GO:0032452 | histone demethylase activity(GO:0032452) |
0.0 | 0.7 | GO:0097472 | cyclin-dependent protein kinase activity(GO:0097472) |
0.0 | 0.3 | GO:0015002 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
0.0 | 0.4 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 4.0 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
0.0 | 0.7 | SA REG CASCADE OF CYCLIN EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
0.0 | 3.3 | PID AJDISS 2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
0.0 | 2.2 | PID ILK PATHWAY | Integrin-linked kinase signaling |
0.0 | 2.1 | PID ARF6 TRAFFICKING PATHWAY | Arf6 trafficking events |
0.0 | 0.9 | PID AURORA A PATHWAY | Aurora A signaling |
0.0 | 1.0 | PID CDC42 REG PATHWAY | Regulation of CDC42 activity |
0.0 | 1.0 | PID THROMBIN PAR1 PATHWAY | PAR1-mediated thrombin signaling events |
0.0 | 0.6 | PID FRA PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
0.0 | 0.9 | PID PLK1 PATHWAY | PLK1 signaling events |
0.0 | 1.3 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
0.0 | 0.7 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
0.0 | 0.7 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
0.0 | 0.1 | PID VEGF VEGFR PATHWAY | VEGF and VEGFR signaling network |
0.0 | 2.6 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
0.0 | 0.5 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 4.0 | REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN | Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin |
0.2 | 3.6 | REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
0.1 | 1.4 | REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION | Genes involved in Cyclin A/B1 associated events during G2/M transition |
0.1 | 2.1 | REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS | Genes involved in Regulation of gene expression in beta cells |
0.1 | 1.7 | REACTOME SIGNALING BY HIPPO | Genes involved in Signaling by Hippo |
0.1 | 1.0 | REACTOME GABA A RECEPTOR ACTIVATION | Genes involved in GABA A receptor activation |
0.0 | 1.8 | REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
0.0 | 0.9 | REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS | Genes involved in Amino acid and oligopeptide SLC transporters |
0.0 | 0.5 | REACTOME CS DS DEGRADATION | Genes involved in CS/DS degradation |
0.0 | 0.5 | REACTOME ACTIVATION OF RAC | Genes involved in Activation of Rac |
0.0 | 0.4 | REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX | Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex |
0.0 | 0.9 | REACTOME METAL ION SLC TRANSPORTERS | Genes involved in Metal ion SLC transporters |
0.0 | 0.6 | REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY | Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery |
0.0 | 0.3 | REACTOME PROCESSING OF INTRONLESS PRE MRNAS | Genes involved in Processing of Intronless Pre-mRNAs |
0.0 | 0.3 | REACTOME EICOSANOID LIGAND BINDING RECEPTORS | Genes involved in Eicosanoid ligand-binding receptors |
0.0 | 0.4 | REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI | Genes involved in Synthesis of glycosylphosphatidylinositol (GPI) |
0.0 | 0.4 | REACTOME OTHER SEMAPHORIN INTERACTIONS | Genes involved in Other semaphorin interactions |
0.0 | 0.4 | REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING | Genes involved in Downregulation of TGF-beta receptor signaling |
0.0 | 1.1 | REACTOME NRAGE SIGNALS DEATH THROUGH JNK | Genes involved in NRAGE signals death through JNK |
0.0 | 0.3 | REACTOME TRAF6 MEDIATED IRF7 ACTIVATION | Genes involved in TRAF6 mediated IRF7 activation |
0.0 | 0.1 | REACTOME VEGF LIGAND RECEPTOR INTERACTIONS | Genes involved in VEGF ligand-receptor interactions |
0.0 | 1.9 | REACTOME PEPTIDE LIGAND BINDING RECEPTORS | Genes involved in Peptide ligand-binding receptors |