avrg: GSE58827: Dynamics of the Mouse Liver
Gene Symbol | Gene ID | Gene Info |
---|---|---|
E2f7
|
ENSMUSG00000020185.10 | E2F transcription factor 7 |
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
E2f7 | mm10_v2_chr10_+_110745433_110745572 | 0.83 | 5.3e-10 | Click! |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
3.0 | 15.1 | GO:0070318 | positive regulation of G0 to G1 transition(GO:0070318) |
1.5 | 4.4 | GO:0031662 | regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) |
1.4 | 8.7 | GO:0009256 | 10-formyltetrahydrofolate metabolic process(GO:0009256) tetrahydrofolate biosynthetic process(GO:0046654) |
1.3 | 4.0 | GO:0045004 | DNA replication proofreading(GO:0045004) |
1.1 | 7.4 | GO:1990086 | lens fiber cell apoptotic process(GO:1990086) |
1.0 | 11.4 | GO:0033314 | mitotic DNA replication checkpoint(GO:0033314) |
0.9 | 16.2 | GO:0009263 | deoxyribonucleotide biosynthetic process(GO:0009263) |
0.9 | 11.2 | GO:2000653 | regulation of genetic imprinting(GO:2000653) |
0.8 | 8.4 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
0.7 | 2.2 | GO:0006597 | spermine biosynthetic process(GO:0006597) |
0.7 | 2.8 | GO:1902340 | telomeric heterochromatin assembly(GO:0031509) negative regulation of chromosome condensation(GO:1902340) |
0.7 | 10.1 | GO:0000212 | meiotic spindle organization(GO:0000212) |
0.7 | 6.1 | GO:0090166 | Golgi disassembly(GO:0090166) |
0.7 | 2.7 | GO:0007066 | female meiosis sister chromatid cohesion(GO:0007066) |
0.7 | 2.0 | GO:1904959 | regulation of electron carrier activity(GO:1904732) regulation of cytochrome-c oxidase activity(GO:1904959) |
0.6 | 1.8 | GO:1901254 | regulation of translation at synapse, modulating synaptic transmission(GO:0099547) regulation of translation at postsynapse, modulating synaptic transmission(GO:0099578) positive regulation of intracellular transport of viral material(GO:1901254) |
0.5 | 2.6 | GO:0000076 | DNA replication checkpoint(GO:0000076) |
0.4 | 3.7 | GO:0016198 | axon choice point recognition(GO:0016198) |
0.4 | 3.6 | GO:0090267 | positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) |
0.3 | 5.3 | GO:0051382 | kinetochore assembly(GO:0051382) |
0.3 | 2.5 | GO:0016584 | nucleosome positioning(GO:0016584) |
0.3 | 3.0 | GO:0030206 | chondroitin sulfate biosynthetic process(GO:0030206) |
0.3 | 0.9 | GO:0032954 | regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490) |
0.3 | 0.9 | GO:0019046 | release from viral latency(GO:0019046) |
0.3 | 3.4 | GO:0000185 | activation of MAPKKK activity(GO:0000185) |
0.2 | 2.5 | GO:0042984 | very-low-density lipoprotein particle assembly(GO:0034379) amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984) |
0.2 | 5.7 | GO:0006270 | DNA replication initiation(GO:0006270) |
0.2 | 24.7 | GO:0006342 | chromatin silencing(GO:0006342) |
0.2 | 1.7 | GO:0000056 | ribosomal small subunit export from nucleus(GO:0000056) |
0.2 | 0.9 | GO:1903984 | positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984) |
0.2 | 6.7 | GO:0034723 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) |
0.2 | 1.1 | GO:0018364 | peptidyl-glutamine methylation(GO:0018364) |
0.2 | 1.1 | GO:1903690 | negative regulation of wound healing, spreading of epidermal cells(GO:1903690) |
0.2 | 6.1 | GO:0060236 | regulation of mitotic spindle organization(GO:0060236) regulation of spindle organization(GO:0090224) |
0.2 | 0.9 | GO:0046600 | histone H2A-K119 monoubiquitination(GO:0036353) negative regulation of centriole replication(GO:0046600) |
0.2 | 2.0 | GO:0002227 | innate immune response in mucosa(GO:0002227) |
0.2 | 2.0 | GO:1901898 | regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844) negative regulation of relaxation of cardiac muscle(GO:1901898) |
0.1 | 1.8 | GO:0007343 | egg activation(GO:0007343) |
0.1 | 1.2 | GO:1900364 | negative regulation of mRNA polyadenylation(GO:1900364) |
0.1 | 2.8 | GO:2000001 | regulation of DNA damage checkpoint(GO:2000001) |
0.1 | 0.5 | GO:0001560 | regulation of cell growth by extracellular stimulus(GO:0001560) |
0.1 | 0.5 | GO:0010286 | heat acclimation(GO:0010286) |
0.1 | 0.3 | GO:1904760 | myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760) |
0.1 | 1.3 | GO:0045631 | regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980) |
0.1 | 3.1 | GO:0044342 | type B pancreatic cell proliferation(GO:0044342) |
0.1 | 0.5 | GO:0090666 | scaRNA localization to Cajal body(GO:0090666) |
0.1 | 3.9 | GO:0003333 | amino acid transmembrane transport(GO:0003333) |
0.1 | 0.8 | GO:0051026 | chiasma assembly(GO:0051026) |
0.1 | 1.4 | GO:0048096 | chromatin-mediated maintenance of transcription(GO:0048096) |
0.1 | 2.2 | GO:0016578 | histone deubiquitination(GO:0016578) |
0.1 | 0.4 | GO:0048014 | Tie signaling pathway(GO:0048014) |
0.1 | 0.4 | GO:0061056 | sclerotome development(GO:0061056) |
0.1 | 4.5 | GO:0032781 | positive regulation of ATPase activity(GO:0032781) |
0.1 | 2.6 | GO:0006378 | mRNA polyadenylation(GO:0006378) |
0.1 | 6.6 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
0.1 | 2.4 | GO:0071391 | cellular response to estrogen stimulus(GO:0071391) |
0.1 | 1.3 | GO:0000289 | nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289) |
0.0 | 0.3 | GO:0010159 | specification of organ position(GO:0010159) |
0.0 | 1.1 | GO:0090031 | positive regulation of steroid hormone biosynthetic process(GO:0090031) |
0.0 | 0.4 | GO:0034427 | nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928) |
0.0 | 2.7 | GO:0006334 | nucleosome assembly(GO:0006334) |
0.0 | 0.2 | GO:0010724 | regulation of definitive erythrocyte differentiation(GO:0010724) |
0.0 | 0.4 | GO:0035457 | cellular response to interferon-alpha(GO:0035457) |
0.0 | 0.4 | GO:0035970 | peptidyl-threonine dephosphorylation(GO:0035970) |
0.0 | 0.1 | GO:1901740 | negative regulation of myoblast fusion(GO:1901740) |
0.0 | 0.2 | GO:0007341 | penetration of zona pellucida(GO:0007341) |
0.0 | 0.6 | GO:0003351 | epithelial cilium movement(GO:0003351) |
0.0 | 1.1 | GO:0043550 | regulation of lipid kinase activity(GO:0043550) |
0.0 | 0.1 | GO:2000467 | positive regulation of glycogen (starch) synthase activity(GO:2000467) |
0.0 | 2.0 | GO:0030010 | establishment of cell polarity(GO:0030010) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
3.2 | 16.2 | GO:0005971 | ribonucleoside-diphosphate reductase complex(GO:0005971) |
2.5 | 20.2 | GO:0000808 | origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664) |
1.3 | 4.0 | GO:0043625 | delta DNA polymerase complex(GO:0043625) |
0.6 | 4.4 | GO:0005638 | lamin filament(GO:0005638) |
0.6 | 1.7 | GO:0031074 | nucleocytoplasmic shuttling complex(GO:0031074) |
0.5 | 2.7 | GO:0048476 | Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063) Holliday junction resolvase complex(GO:0048476) |
0.4 | 1.8 | GO:1902737 | viral replication complex(GO:0019034) dendritic filopodium(GO:1902737) |
0.4 | 2.8 | GO:0001740 | Barr body(GO:0001740) |
0.4 | 5.4 | GO:0042555 | MCM complex(GO:0042555) |
0.4 | 2.6 | GO:0031298 | replication fork protection complex(GO:0031298) |
0.4 | 0.4 | GO:0055087 | Ski complex(GO:0055087) |
0.3 | 2.6 | GO:0042382 | paraspeckles(GO:0042382) |
0.3 | 1.2 | GO:0032021 | NELF complex(GO:0032021) |
0.3 | 20.6 | GO:0000786 | nucleosome(GO:0000786) |
0.3 | 1.1 | GO:0030981 | cortical microtubule cytoskeleton(GO:0030981) |
0.2 | 13.2 | GO:0005876 | spindle microtubule(GO:0005876) |
0.2 | 1.1 | GO:0001651 | dense fibrillar component(GO:0001651) |
0.2 | 2.8 | GO:0005662 | DNA replication factor A complex(GO:0005662) |
0.2 | 3.0 | GO:0032580 | Golgi cisterna membrane(GO:0032580) |
0.1 | 10.5 | GO:0005844 | polysome(GO:0005844) |
0.1 | 11.0 | GO:0072686 | mitotic spindle(GO:0072686) |
0.1 | 2.4 | GO:0035327 | transcriptionally active chromatin(GO:0035327) |
0.1 | 1.4 | GO:0043596 | nuclear replication fork(GO:0043596) |
0.1 | 0.9 | GO:0070461 | SAGA-type complex(GO:0070461) |
0.1 | 1.9 | GO:0071011 | precatalytic spliceosome(GO:0071011) |
0.1 | 10.8 | GO:0090575 | RNA polymerase II transcription factor complex(GO:0090575) |
0.1 | 1.4 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
0.0 | 0.8 | GO:0070822 | Sin3-type complex(GO:0070822) |
0.0 | 5.3 | GO:0000776 | kinetochore(GO:0000776) |
0.0 | 13.8 | GO:0000790 | nuclear chromatin(GO:0000790) |
0.0 | 2.0 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
0.0 | 2.0 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
0.0 | 2.0 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
0.0 | 1.3 | GO:0030672 | synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501) |
0.0 | 0.1 | GO:0016593 | Cdc73/Paf1 complex(GO:0016593) |
0.0 | 0.2 | GO:0042582 | primary lysosome(GO:0005766) azurophil granule(GO:0042582) |
0.0 | 0.5 | GO:0005871 | kinesin complex(GO:0005871) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
3.2 | 16.2 | GO:0016728 | ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731) |
2.2 | 8.7 | GO:0004488 | methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488) |
2.2 | 10.8 | GO:0043515 | kinetochore binding(GO:0043515) |
1.9 | 11.4 | GO:0010997 | anaphase-promoting complex binding(GO:0010997) |
1.0 | 3.0 | GO:0050510 | N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510) |
0.8 | 6.3 | GO:0008821 | crossover junction endodeoxyribonuclease activity(GO:0008821) |
0.8 | 10.8 | GO:0003688 | DNA replication origin binding(GO:0003688) |
0.4 | 5.8 | GO:0045294 | alpha-catenin binding(GO:0045294) |
0.3 | 7.1 | GO:0008353 | RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353) |
0.3 | 2.2 | GO:0019808 | polyamine binding(GO:0019808) |
0.3 | 1.7 | GO:0070883 | pre-miRNA binding(GO:0070883) |
0.3 | 4.0 | GO:0008296 | 3'-5'-exodeoxyribonuclease activity(GO:0008296) |
0.3 | 1.8 | GO:0033592 | RNA strand annealing activity(GO:0033592) |
0.2 | 2.0 | GO:0016531 | copper chaperone activity(GO:0016531) |
0.2 | 0.7 | GO:0008107 | galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127) |
0.2 | 4.4 | GO:0008432 | JUN kinase binding(GO:0008432) |
0.1 | 0.9 | GO:0051425 | PTB domain binding(GO:0051425) |
0.1 | 1.1 | GO:0001094 | TFIID-class transcription factor binding(GO:0001094) |
0.1 | 6.5 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
0.1 | 10.3 | GO:0004197 | cysteine-type endopeptidase activity(GO:0004197) |
0.1 | 1.3 | GO:0098505 | G-rich strand telomeric DNA binding(GO:0098505) |
0.1 | 0.9 | GO:0046972 | histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972) |
0.1 | 3.3 | GO:0004003 | ATP-dependent DNA helicase activity(GO:0004003) |
0.1 | 0.4 | GO:0004724 | magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724) |
0.1 | 1.3 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
0.1 | 2.5 | GO:0000062 | fatty-acyl-CoA binding(GO:0000062) |
0.1 | 3.7 | GO:0046875 | ephrin receptor binding(GO:0046875) |
0.1 | 1.4 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
0.1 | 2.0 | GO:0004115 | 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) |
0.0 | 0.2 | GO:0001069 | regulatory region RNA binding(GO:0001069) |
0.0 | 2.5 | GO:0031490 | chromatin DNA binding(GO:0031490) |
0.0 | 1.8 | GO:0050699 | WW domain binding(GO:0050699) |
0.0 | 0.3 | GO:0003909 | DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910) |
0.0 | 10.1 | GO:0001047 | core promoter binding(GO:0001047) |
0.0 | 1.1 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
0.0 | 2.0 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
0.0 | 6.0 | GO:0042393 | histone binding(GO:0042393) |
0.0 | 0.2 | GO:0004563 | beta-N-acetylhexosaminidase activity(GO:0004563) |
0.0 | 9.6 | GO:0061630 | ubiquitin protein ligase activity(GO:0061630) |
0.0 | 0.8 | GO:0004407 | histone deacetylase activity(GO:0004407) |
0.0 | 3.7 | GO:0031072 | heat shock protein binding(GO:0031072) |
0.0 | 0.1 | GO:0048248 | CXCR3 chemokine receptor binding(GO:0048248) |
0.0 | 0.3 | GO:0071837 | HMG box domain binding(GO:0071837) |
0.0 | 3.9 | GO:0001227 | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227) |
0.0 | 1.7 | GO:0015171 | amino acid transmembrane transporter activity(GO:0015171) |
0.0 | 0.5 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
0.0 | 6.7 | GO:0003682 | chromatin binding(GO:0003682) |
0.0 | 2.0 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
0.0 | 0.7 | GO:0005246 | calcium channel regulator activity(GO:0005246) |
0.0 | 3.1 | GO:0008017 | microtubule binding(GO:0008017) |
0.0 | 6.8 | GO:0046982 | protein heterodimerization activity(GO:0046982) |
0.0 | 0.8 | GO:0005546 | phosphatidylinositol-4,5-bisphosphate binding(GO:0005546) |
0.0 | 1.1 | GO:0005179 | hormone activity(GO:0005179) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.0 | 9.1 | SA G2 AND M PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
0.5 | 7.4 | SA G1 AND S PHASES | Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition. |
0.5 | 21.9 | PID ATR PATHWAY | ATR signaling pathway |
0.4 | 32.4 | PID E2F PATHWAY | E2F transcription factor network |
0.2 | 2.5 | ST JAK STAT PATHWAY | Jak-STAT Pathway |
0.1 | 5.2 | PID AURORA A PATHWAY | Aurora A signaling |
0.1 | 2.4 | PID AR NONGENOMIC PATHWAY | Nongenotropic Androgen signaling |
0.1 | 8.3 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
0.1 | 4.7 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
0.1 | 3.7 | PID EPHB FWD PATHWAY | EPHB forward signaling |
0.1 | 1.4 | PID ATM PATHWAY | ATM pathway |
0.1 | 2.1 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
0.0 | 1.4 | PID RHOA REG PATHWAY | Regulation of RhoA activity |
0.0 | 1.3 | PID SMAD2 3NUCLEAR PATHWAY | Regulation of nuclear SMAD2/3 signaling |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.2 | 22.2 | REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION | Genes involved in E2F-enabled inhibition of pre-replication complex formation |
1.5 | 7.4 | REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX | Genes involved in CDC6 association with the ORC:origin complex |
1.2 | 16.2 | REACTOME G1 S SPECIFIC TRANSCRIPTION | Genes involved in G1/S-Specific Transcription |
1.1 | 14.1 | REACTOME UNWINDING OF DNA | Genes involved in Unwinding of DNA |
0.8 | 6.8 | REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND | Genes involved in Removal of the Flap Intermediate from the C-strand |
0.4 | 21.3 | REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
0.3 | 6.5 | REACTOME RNA POL I PROMOTER OPENING | Genes involved in RNA Polymerase I Promoter Opening |
0.2 | 2.0 | REACTOME G2 M DNA DAMAGE CHECKPOINT | Genes involved in G2/M DNA damage checkpoint |
0.2 | 6.6 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
0.2 | 2.5 | REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION | Genes involved in Apoptosis induced DNA fragmentation |
0.1 | 3.0 | REACTOME CHONDROITIN SULFATE BIOSYNTHESIS | Genes involved in Chondroitin sulfate biosynthesis |
0.1 | 3.5 | REACTOME MEIOTIC RECOMBINATION | Genes involved in Meiotic Recombination |
0.1 | 4.4 | REACTOME MEIOTIC SYNAPSIS | Genes involved in Meiotic Synapsis |
0.1 | 1.3 | REACTOME ACTIVATION OF RAC | Genes involved in Activation of Rac |
0.1 | 2.6 | REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY | Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery |
0.1 | 1.1 | REACTOME G0 AND EARLY G1 | Genes involved in G0 and Early G1 |
0.1 | 1.9 | REACTOME SIGNALING BY ROBO RECEPTOR | Genes involved in Signaling by Robo receptor |
0.1 | 2.6 | REACTOME SIGNALING BY FGFR1 FUSION MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |
0.0 | 2.0 | REACTOME DARPP 32 EVENTS | Genes involved in DARPP-32 events |
0.0 | 1.2 | REACTOME DEADENYLATION OF MRNA | Genes involved in Deadenylation of mRNA |
0.0 | 2.0 | REACTOME MITOCHONDRIAL PROTEIN IMPORT | Genes involved in Mitochondrial Protein Import |
0.0 | 0.9 | REACTOME ACTIVATION OF GENES BY ATF4 | Genes involved in Activation of Genes by ATF4 |
0.0 | 0.2 | REACTOME CS DS DEGRADATION | Genes involved in CS/DS degradation |
0.0 | 0.5 | REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC | Genes involved in Formation of tubulin folding intermediates by CCT/TriC |
0.0 | 0.4 | REACTOME TIE2 SIGNALING | Genes involved in Tie2 Signaling |
0.0 | 2.0 | REACTOME PEPTIDE CHAIN ELONGATION | Genes involved in Peptide chain elongation |
0.0 | 0.5 | REACTOME KINESINS | Genes involved in Kinesins |
0.0 | 0.7 | REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION | Genes involved in Glucagon signaling in metabolic regulation |
0.0 | 0.3 | REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY | Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity |