avrg: GSE58827: Dynamics of the Mouse Liver
Gene Symbol | Gene ID | Gene Info |
---|---|---|
Lhx4
|
ENSMUSG00000026468.8 | LIM homeobox protein 4 |
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Lhx4 | mm10_v2_chr1_-_155742120_155742136 | 0.09 | 6.1e-01 | Click! |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 0.9 | GO:1905000 | regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000) |
0.2 | 0.5 | GO:0001928 | regulation of exocyst assembly(GO:0001928) |
0.1 | 1.2 | GO:1901750 | leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750) |
0.1 | 0.6 | GO:0044268 | multicellular organismal protein metabolic process(GO:0044268) |
0.1 | 0.4 | GO:0030210 | heparin biosynthetic process(GO:0030210) |
0.1 | 0.4 | GO:1901074 | regulation of engulfment of apoptotic cell(GO:1901074) |
0.1 | 0.9 | GO:0021555 | midbrain-hindbrain boundary morphogenesis(GO:0021555) |
0.1 | 1.1 | GO:0030916 | otic vesicle formation(GO:0030916) |
0.1 | 0.8 | GO:0033353 | S-adenosylmethionine cycle(GO:0033353) |
0.1 | 0.5 | GO:0038032 | termination of G-protein coupled receptor signaling pathway(GO:0038032) |
0.1 | 0.2 | GO:1904173 | regulation of histone demethylase activity (H3-K4 specific)(GO:1904173) |
0.1 | 0.4 | GO:0061146 | Peyer's patch morphogenesis(GO:0061146) |
0.1 | 0.3 | GO:1900369 | negative regulation of RNA interference(GO:1900369) |
0.1 | 0.3 | GO:0060488 | orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490) |
0.1 | 0.3 | GO:0046379 | extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379) |
0.1 | 0.2 | GO:0061076 | camera-type eye photoreceptor cell fate commitment(GO:0060220) negative regulation of neural retina development(GO:0061076) negative regulation of retina development in camera-type eye(GO:1902867) negative regulation of amacrine cell differentiation(GO:1902870) |
0.1 | 0.4 | GO:2000473 | immunoglobulin biosynthetic process(GO:0002378) regulation of hematopoietic stem cell migration(GO:2000471) positive regulation of hematopoietic stem cell migration(GO:2000473) |
0.1 | 0.3 | GO:0035502 | metanephric part of ureteric bud development(GO:0035502) |
0.1 | 0.5 | GO:1901164 | negative regulation of trophoblast cell migration(GO:1901164) |
0.1 | 0.2 | GO:0050925 | negative regulation of negative chemotaxis(GO:0050925) |
0.1 | 0.3 | GO:0060005 | vestibular reflex(GO:0060005) |
0.1 | 0.4 | GO:0090520 | sphingolipid mediated signaling pathway(GO:0090520) |
0.1 | 0.2 | GO:0033375 | protein localization to secretory granule(GO:0033366) protein localization to mast cell secretory granule(GO:0033367) protease localization to mast cell secretory granule(GO:0033368) maintenance of protein location in mast cell secretory granule(GO:0033370) T cell secretory granule organization(GO:0033371) maintenance of protease location in mast cell secretory granule(GO:0033373) protein localization to T cell secretory granule(GO:0033374) protease localization to T cell secretory granule(GO:0033375) maintenance of protein location in T cell secretory granule(GO:0033377) maintenance of protease location in T cell secretory granule(GO:0033379) granzyme B localization to T cell secretory granule(GO:0033380) maintenance of granzyme B location in T cell secretory granule(GO:0033382) |
0.1 | 0.2 | GO:1904425 | negative regulation of GTP binding(GO:1904425) |
0.1 | 0.6 | GO:0007342 | fusion of sperm to egg plasma membrane(GO:0007342) |
0.1 | 0.6 | GO:0010944 | negative regulation of transcription by competitive promoter binding(GO:0010944) |
0.0 | 0.2 | GO:1904124 | microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139) |
0.0 | 0.1 | GO:0006597 | spermine biosynthetic process(GO:0006597) |
0.0 | 0.6 | GO:0048934 | peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935) |
0.0 | 0.2 | GO:0061386 | closure of optic fissure(GO:0061386) |
0.0 | 0.6 | GO:0042541 | hemoglobin biosynthetic process(GO:0042541) |
0.0 | 0.3 | GO:0097118 | neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118) |
0.0 | 0.1 | GO:0060168 | thiamine metabolic process(GO:0006772) thiamine-containing compound metabolic process(GO:0042723) positive regulation of adenosine receptor signaling pathway(GO:0060168) |
0.0 | 0.5 | GO:0046884 | follicle-stimulating hormone secretion(GO:0046884) |
0.0 | 0.1 | GO:0010700 | negative regulation of norepinephrine secretion(GO:0010700) |
0.0 | 0.2 | GO:0001550 | ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) |
0.0 | 1.7 | GO:1900026 | positive regulation of substrate adhesion-dependent cell spreading(GO:1900026) |
0.0 | 0.1 | GO:1904753 | regulation of phenotypic switching(GO:1900239) negative regulation of vascular associated smooth muscle cell migration(GO:1904753) regulation of cardiac vascular smooth muscle cell differentiation(GO:2000722) positive regulation of cardiac vascular smooth muscle cell differentiation(GO:2000724) |
0.0 | 0.2 | GO:0045162 | clustering of voltage-gated sodium channels(GO:0045162) |
0.0 | 0.2 | GO:0021776 | smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776) |
0.0 | 4.0 | GO:0007586 | digestion(GO:0007586) |
0.0 | 0.3 | GO:0007213 | G-protein coupled acetylcholine receptor signaling pathway(GO:0007213) |
0.0 | 0.1 | GO:0038128 | ERBB2 signaling pathway(GO:0038128) |
0.0 | 0.1 | GO:0010808 | positive regulation of synaptic vesicle priming(GO:0010808) |
0.0 | 0.1 | GO:2000849 | glucocorticoid secretion(GO:0035933) regulation of glucocorticoid secretion(GO:2000849) |
0.0 | 0.1 | GO:0001830 | trophectodermal cell fate commitment(GO:0001830) |
0.0 | 0.1 | GO:0048478 | replication fork protection(GO:0048478) |
0.0 | 0.1 | GO:0010133 | proline catabolic process to glutamate(GO:0010133) |
0.0 | 0.2 | GO:0045631 | regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980) |
0.0 | 0.4 | GO:0042415 | norepinephrine metabolic process(GO:0042415) |
0.0 | 0.8 | GO:0050869 | negative regulation of B cell activation(GO:0050869) |
0.0 | 0.4 | GO:0097150 | neuronal stem cell population maintenance(GO:0097150) |
0.0 | 0.1 | GO:0014005 | microglia differentiation(GO:0014004) microglia development(GO:0014005) |
0.0 | 0.4 | GO:0000028 | ribosomal small subunit assembly(GO:0000028) |
0.0 | 0.7 | GO:0048791 | calcium ion-regulated exocytosis of neurotransmitter(GO:0048791) |
0.0 | 0.1 | GO:0035726 | common myeloid progenitor cell proliferation(GO:0035726) |
0.0 | 0.1 | GO:1903215 | negative regulation of protein targeting to mitochondrion(GO:1903215) |
0.0 | 0.3 | GO:0060736 | prostate gland growth(GO:0060736) |
0.0 | 0.1 | GO:0060040 | retinal bipolar neuron differentiation(GO:0060040) |
0.0 | 0.1 | GO:0060591 | chondroblast differentiation(GO:0060591) |
0.0 | 0.3 | GO:0048490 | anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517) |
0.0 | 0.1 | GO:0031848 | protection from non-homologous end joining at telomere(GO:0031848) |
0.0 | 0.5 | GO:0006376 | mRNA splice site selection(GO:0006376) |
0.0 | 0.2 | GO:1904659 | glucose transmembrane transport(GO:1904659) |
0.0 | 0.2 | GO:0045898 | regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898) |
0.0 | 0.5 | GO:0016601 | Rac protein signal transduction(GO:0016601) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 0.9 | GO:0031523 | Myb complex(GO:0031523) |
0.1 | 1.7 | GO:0042581 | specific granule(GO:0042581) |
0.1 | 0.3 | GO:0060187 | cell pole(GO:0060187) |
0.0 | 0.3 | GO:0044530 | supraspliceosomal complex(GO:0044530) |
0.0 | 1.0 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
0.0 | 0.3 | GO:1990393 | 3M complex(GO:1990393) |
0.0 | 0.2 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
0.0 | 0.5 | GO:0032045 | guanyl-nucleotide exchange factor complex(GO:0032045) |
0.0 | 0.5 | GO:0036056 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
0.0 | 0.2 | GO:0071439 | clathrin complex(GO:0071439) |
0.0 | 0.2 | GO:0034750 | Scrib-APC-beta-catenin complex(GO:0034750) |
0.0 | 0.3 | GO:0030123 | AP-3 adaptor complex(GO:0030123) |
0.0 | 0.1 | GO:0098831 | presynaptic active zone cytoplasmic component(GO:0098831) |
0.0 | 0.2 | GO:0042629 | mast cell granule(GO:0042629) |
0.0 | 0.6 | GO:0002080 | acrosomal membrane(GO:0002080) |
0.0 | 0.1 | GO:0031298 | replication fork protection complex(GO:0031298) |
0.0 | 0.1 | GO:0071007 | U2-type catalytic step 2 spliceosome(GO:0071007) |
0.0 | 0.4 | GO:0001891 | phagocytic cup(GO:0001891) |
0.0 | 0.5 | GO:0097440 | apical dendrite(GO:0097440) |
0.0 | 0.1 | GO:0042406 | extrinsic component of endoplasmic reticulum membrane(GO:0042406) |
0.0 | 0.0 | GO:0030981 | cortical microtubule cytoskeleton(GO:0030981) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 0.6 | GO:0071820 | N-box binding(GO:0071820) |
0.2 | 0.6 | GO:0016748 | succinyltransferase activity(GO:0016748) |
0.2 | 0.9 | GO:0034988 | Fc-gamma receptor I complex binding(GO:0034988) |
0.1 | 0.4 | GO:0030226 | apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556) |
0.1 | 0.8 | GO:0004013 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
0.1 | 0.6 | GO:0003989 | acetyl-CoA carboxylase activity(GO:0003989) |
0.1 | 1.2 | GO:0036374 | glutathione hydrolase activity(GO:0036374) |
0.1 | 0.3 | GO:0003692 | left-handed Z-DNA binding(GO:0003692) |
0.1 | 0.6 | GO:0086080 | protein binding involved in heterotypic cell-cell adhesion(GO:0086080) |
0.1 | 0.3 | GO:0050501 | hyaluronan synthase activity(GO:0050501) |
0.1 | 0.5 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
0.1 | 0.2 | GO:0004605 | phosphatidate cytidylyltransferase activity(GO:0004605) |
0.0 | 0.3 | GO:0070699 | type II activin receptor binding(GO:0070699) |
0.0 | 1.0 | GO:0070016 | armadillo repeat domain binding(GO:0070016) |
0.0 | 0.1 | GO:0070996 | type 1 melanocortin receptor binding(GO:0070996) |
0.0 | 0.3 | GO:0005499 | vitamin D binding(GO:0005499) |
0.0 | 1.1 | GO:0048027 | mRNA 5'-UTR binding(GO:0048027) |
0.0 | 0.2 | GO:0004957 | prostaglandin E receptor activity(GO:0004957) |
0.0 | 0.5 | GO:0030275 | LRR domain binding(GO:0030275) |
0.0 | 2.1 | GO:0001190 | transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811) |
0.0 | 0.4 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
0.0 | 0.1 | GO:0019808 | polyamine binding(GO:0019808) |
0.0 | 0.2 | GO:0008046 | axon guidance receptor activity(GO:0008046) |
0.0 | 0.3 | GO:0005172 | vascular endothelial growth factor receptor binding(GO:0005172) |
0.0 | 0.2 | GO:0001609 | G-protein coupled adenosine receptor activity(GO:0001609) |
0.0 | 0.5 | GO:0097602 | cullin family protein binding(GO:0097602) |
0.0 | 0.1 | GO:0033265 | choline binding(GO:0033265) |
0.0 | 0.8 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
0.0 | 3.1 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
0.0 | 0.0 | GO:0008330 | protein tyrosine/threonine phosphatase activity(GO:0008330) |
0.0 | 0.1 | GO:0031802 | type 5 metabotropic glutamate receptor binding(GO:0031802) |
0.0 | 0.2 | GO:0005025 | transforming growth factor beta receptor activity, type I(GO:0005025) |
0.0 | 0.2 | GO:0005412 | glucose:sodium symporter activity(GO:0005412) |
0.0 | 0.2 | GO:0070411 | alpha-catenin binding(GO:0045294) I-SMAD binding(GO:0070411) histone methyltransferase binding(GO:1990226) |
0.0 | 0.8 | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547) |
0.0 | 0.4 | GO:0043395 | heparan sulfate proteoglycan binding(GO:0043395) |
0.0 | 0.3 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
0.0 | 0.1 | GO:0035312 | 5'-3' exodeoxyribonuclease activity(GO:0035312) |
0.0 | 0.3 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
0.0 | 0.1 | GO:0036122 | BMP binding(GO:0036122) |
0.0 | 0.5 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
0.0 | 0.9 | GO:0030276 | clathrin binding(GO:0030276) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 0.9 | PID ARF6 PATHWAY | Arf6 signaling events |
0.0 | 0.9 | PID WNT NONCANONICAL PATHWAY | Noncanonical Wnt signaling pathway |
0.0 | 0.6 | PID P38 MK2 PATHWAY | p38 signaling mediated by MAPKAP kinases |
0.0 | 0.5 | PID IL8 CXCR2 PATHWAY | IL8- and CXCR2-mediated signaling events |
0.0 | 0.7 | PID ER NONGENOMIC PATHWAY | Plasma membrane estrogen receptor signaling |
0.0 | 0.2 | PID SYNDECAN 3 PATHWAY | Syndecan-3-mediated signaling events |
0.0 | 0.5 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 0.5 | REACTOME HORMONE LIGAND BINDING RECEPTORS | Genes involved in Hormone ligand-binding receptors |
0.0 | 1.2 | REACTOME GLUTATHIONE CONJUGATION | Genes involved in Glutathione conjugation |
0.0 | 0.6 | REACTOME METABOLISM OF PORPHYRINS | Genes involved in Metabolism of porphyrins |
0.0 | 0.4 | REACTOME TIE2 SIGNALING | Genes involved in Tie2 Signaling |
0.0 | 0.4 | REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS | Genes involved in Phosphorylation of CD3 and TCR zeta chains |
0.0 | 0.3 | REACTOME HYALURONAN METABOLISM | Genes involved in Hyaluronan metabolism |
0.0 | 0.3 | REACTOME CS DS DEGRADATION | Genes involved in CS/DS degradation |
0.0 | 0.1 | REACTOME PEPTIDE HORMONE BIOSYNTHESIS | Genes involved in Peptide hormone biosynthesis |
0.0 | 0.2 | REACTOME PROSTANOID LIGAND RECEPTORS | Genes involved in Prostanoid ligand receptors |
0.0 | 0.4 | REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS | Genes involved in ABCA transporters in lipid homeostasis |
0.0 | 0.5 | REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS | Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis |
0.0 | 0.6 | REACTOME FATTY ACYL COA BIOSYNTHESIS | Genes involved in Fatty Acyl-CoA Biosynthesis |
0.0 | 0.2 | REACTOME P2Y RECEPTORS | Genes involved in P2Y receptors |
0.0 | 0.2 | REACTOME SIGNALING BY PDGF | Genes involved in Signaling by PDGF |
0.0 | 0.2 | REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS | Genes involved in Apoptotic cleavage of cell adhesion proteins |
0.0 | 0.5 | REACTOME SIGNAL TRANSDUCTION BY L1 | Genes involved in Signal transduction by L1 |
0.0 | 0.2 | REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS | Genes involved in Termination of O-glycan biosynthesis |