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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Gbx2

Z-value: 0.32

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Transcription factors associated with Gbx2

Gene Symbol Gene ID Gene Info
ENSMUSG00000034486.7 gastrulation brain homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Gbx2mm10_v2_chr1_-_89933290_899332900.105.5e-01Click!

Activity profile of Gbx2 motif

Sorted Z-values of Gbx2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Gbx2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0045575 basophil activation(GO:0045575)
0.2 1.0 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.1 0.7 GO:0042938 dipeptide transport(GO:0042938)
0.1 1.3 GO:0046549 retinal cone cell development(GO:0046549)
0.1 0.3 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.0 0.4 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.1 GO:0036292 DNA rewinding(GO:0036292)
0.0 0.2 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.0 0.5 GO:0060710 chorio-allantoic fusion(GO:0060710)
0.0 0.1 GO:2000566 antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway(GO:0002488) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent(GO:0002489) positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566)
0.0 0.3 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.2 GO:0042706 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.0 0.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.2 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.1 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.1 GO:0060762 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) regulation of branching involved in mammary gland duct morphogenesis(GO:0060762) germline stem cell asymmetric division(GO:0098728)
0.0 0.1 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.0 0.3 GO:0008340 determination of adult lifespan(GO:0008340)
0.0 0.1 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.0 0.1 GO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902166)
0.0 0.1 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.1 0.5 GO:0070652 HAUS complex(GO:0070652)
0.1 0.2 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.1 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.9 GO:0002102 podosome(GO:0002102)
0.0 0.3 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.0 GO:0097637 intrinsic component of autophagosome membrane(GO:0097636) integral component of autophagosome membrane(GO:0097637)
0.0 0.1 GO:0042612 MHC class I protein complex(GO:0042612)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0042936 dipeptide transporter activity(GO:0042936)
0.1 1.0 GO:0000150 recombinase activity(GO:0000150)
0.1 0.5 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 1.6 GO:0030553 cGMP binding(GO:0030553)
0.1 0.3 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.1 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.2 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.2 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.1 GO:0070287 ferritin receptor activity(GO:0070287)
0.0 0.1 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 0.3 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.1 GO:0043532 angiostatin binding(GO:0043532)
0.0 0.1 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.1 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.4 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.5 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.9 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.2 PID LPA4 PATHWAY LPA4-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.2 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.2 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand