avrg: GSE58827: Dynamics of the Mouse Liver
Gene Symbol | Gene ID | Gene Info |
---|---|---|
Tcf7
|
ENSMUSG00000000782.9 | transcription factor 7, T cell specific |
Tcf7l2
|
ENSMUSG00000024985.12 | transcription factor 7 like 2, T cell specific, HMG box |
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Tcf7 | mm10_v2_chr11_-_52282564_52282579 | 0.77 | 4.3e-08 | Click! |
Tcf7l2 | mm10_v2_chr19_+_55894508_55894534 | 0.55 | 4.8e-04 | Click! |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.1 | 6.3 | GO:0061181 | regulation of chondrocyte development(GO:0061181) |
0.8 | 2.5 | GO:0034443 | negative regulation of lipoprotein oxidation(GO:0034443) multicellular organism lipid catabolic process(GO:0044240) |
0.8 | 2.3 | GO:2000229 | pancreatic stellate cell proliferation(GO:0072343) regulation of pancreatic stellate cell proliferation(GO:2000229) |
0.6 | 8.0 | GO:0002002 | regulation of angiotensin levels in blood(GO:0002002) |
0.6 | 4.5 | GO:0038028 | insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) |
0.6 | 1.7 | GO:0072139 | glomerular parietal epithelial cell differentiation(GO:0072139) |
0.5 | 1.5 | GO:0009753 | response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395) |
0.4 | 4.9 | GO:0052697 | flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697) |
0.4 | 1.5 | GO:1902093 | positive regulation of sperm motility(GO:1902093) |
0.3 | 1.0 | GO:0042939 | glutathione transport(GO:0034635) tripeptide transport(GO:0042939) |
0.3 | 0.8 | GO:0060435 | bronchiole development(GO:0060435) metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277) |
0.3 | 1.3 | GO:0006572 | tyrosine catabolic process(GO:0006572) |
0.2 | 1.7 | GO:0014005 | microglia differentiation(GO:0014004) microglia development(GO:0014005) |
0.2 | 0.7 | GO:0032685 | negative regulation of granulocyte macrophage colony-stimulating factor production(GO:0032685) |
0.2 | 2.9 | GO:2000653 | regulation of genetic imprinting(GO:2000653) |
0.2 | 1.8 | GO:0003096 | renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294) |
0.2 | 0.8 | GO:0046351 | disaccharide biosynthetic process(GO:0046351) |
0.2 | 2.5 | GO:0046549 | retinal cone cell development(GO:0046549) |
0.2 | 1.2 | GO:0008355 | olfactory learning(GO:0008355) |
0.2 | 1.4 | GO:0035948 | positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) |
0.2 | 0.9 | GO:1904970 | brush border assembly(GO:1904970) |
0.2 | 0.9 | GO:0000103 | sulfate assimilation(GO:0000103) |
0.2 | 0.9 | GO:0010760 | negative regulation of macrophage chemotaxis(GO:0010760) |
0.2 | 1.3 | GO:0030421 | defecation(GO:0030421) |
0.2 | 0.7 | GO:0035589 | G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589) |
0.2 | 0.9 | GO:2001013 | epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013) |
0.2 | 0.2 | GO:0007521 | muscle cell fate determination(GO:0007521) |
0.2 | 0.5 | GO:0046104 | pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859) thymidine metabolic process(GO:0046104) |
0.1 | 0.9 | GO:0050747 | positive regulation of lipoprotein metabolic process(GO:0050747) |
0.1 | 1.4 | GO:0042483 | negative regulation of odontogenesis(GO:0042483) |
0.1 | 0.8 | GO:1903054 | negative regulation of extracellular matrix organization(GO:1903054) |
0.1 | 2.0 | GO:0071578 | zinc II ion transmembrane import(GO:0071578) |
0.1 | 0.4 | GO:0060585 | regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585) |
0.1 | 1.1 | GO:0048207 | vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) |
0.1 | 1.0 | GO:0045919 | positive regulation of cytolysis(GO:0045919) |
0.1 | 0.6 | GO:0016557 | peroxisome membrane biogenesis(GO:0016557) |
0.1 | 0.2 | GO:0018879 | biphenyl metabolic process(GO:0018879) |
0.1 | 3.4 | GO:0019373 | epoxygenase P450 pathway(GO:0019373) |
0.1 | 0.3 | GO:0034148 | regulation of granuloma formation(GO:0002631) negative regulation of granuloma formation(GO:0002632) regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573) |
0.1 | 0.5 | GO:0015788 | UDP-N-acetylglucosamine transport(GO:0015788) |
0.1 | 0.6 | GO:0034197 | blood coagulation, intrinsic pathway(GO:0007597) acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197) |
0.1 | 1.5 | GO:0016540 | protein autoprocessing(GO:0016540) |
0.1 | 0.5 | GO:0060666 | dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666) |
0.1 | 1.0 | GO:0035845 | photoreceptor cell outer segment organization(GO:0035845) |
0.1 | 0.6 | GO:0048842 | positive regulation of axon extension involved in axon guidance(GO:0048842) |
0.1 | 1.3 | GO:0030049 | muscle filament sliding(GO:0030049) |
0.1 | 0.9 | GO:0019367 | fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) |
0.1 | 1.7 | GO:0001967 | suckling behavior(GO:0001967) |
0.1 | 0.4 | GO:0051661 | maintenance of centrosome location(GO:0051661) |
0.1 | 0.7 | GO:0010587 | miRNA catabolic process(GO:0010587) |
0.1 | 0.4 | GO:0010989 | negative regulation of low-density lipoprotein particle clearance(GO:0010989) |
0.1 | 0.2 | GO:0002355 | detection of tumor cell(GO:0002355) |
0.1 | 2.1 | GO:0045109 | intermediate filament organization(GO:0045109) |
0.1 | 0.6 | GO:1903849 | regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849) |
0.1 | 0.1 | GO:0000320 | re-entry into mitotic cell cycle(GO:0000320) |
0.1 | 0.3 | GO:1900368 | regulation of RNA interference(GO:1900368) |
0.1 | 0.6 | GO:0008300 | isoprenoid catabolic process(GO:0008300) |
0.1 | 0.2 | GO:0032290 | peripheral nervous system myelin formation(GO:0032290) |
0.1 | 1.2 | GO:0032252 | secretory granule localization(GO:0032252) |
0.1 | 0.5 | GO:0071577 | zinc II ion transmembrane transport(GO:0071577) |
0.1 | 0.2 | GO:0042977 | regulation of activation of JAK2 kinase activity(GO:0010534) activation of JAK2 kinase activity(GO:0042977) negative regulation of activation of JAK2 kinase activity(GO:1902569) |
0.1 | 2.0 | GO:0048339 | paraxial mesoderm development(GO:0048339) |
0.1 | 2.9 | GO:1901998 | toxin transport(GO:1901998) |
0.1 | 0.6 | GO:0035435 | phosphate ion transmembrane transport(GO:0035435) |
0.1 | 0.2 | GO:0000973 | posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973) |
0.1 | 0.7 | GO:0030299 | intestinal cholesterol absorption(GO:0030299) |
0.0 | 0.7 | GO:0000212 | meiotic spindle organization(GO:0000212) |
0.0 | 0.2 | GO:0072362 | regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072362) |
0.0 | 0.7 | GO:0043402 | glucocorticoid mediated signaling pathway(GO:0043402) |
0.0 | 0.1 | GO:0050883 | regulation of sulfur amino acid metabolic process(GO:0031335) musculoskeletal movement, spinal reflex action(GO:0050883) |
0.0 | 0.5 | GO:0035372 | protein localization to microtubule(GO:0035372) |
0.0 | 0.2 | GO:0003273 | cell migration involved in endocardial cushion formation(GO:0003273) condensed mesenchymal cell proliferation(GO:0072137) |
0.0 | 1.4 | GO:0015991 | ATP hydrolysis coupled proton transport(GO:0015991) |
0.0 | 0.3 | GO:0007296 | vitellogenesis(GO:0007296) |
0.0 | 0.1 | GO:1904457 | positive regulation of neuronal action potential(GO:1904457) |
0.0 | 0.5 | GO:0048935 | peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935) |
0.0 | 0.2 | GO:0036324 | vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324) |
0.0 | 0.2 | GO:0051142 | regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142) |
0.0 | 0.4 | GO:0050882 | voluntary musculoskeletal movement(GO:0050882) |
0.0 | 1.7 | GO:0021952 | central nervous system projection neuron axonogenesis(GO:0021952) |
0.0 | 0.3 | GO:0001766 | membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580) |
0.0 | 0.3 | GO:0015961 | diadenosine polyphosphate catabolic process(GO:0015961) |
0.0 | 0.5 | GO:0035988 | chondrocyte proliferation(GO:0035988) |
0.0 | 0.2 | GO:1904798 | positive regulation of core promoter binding(GO:1904798) |
0.0 | 0.2 | GO:0051697 | protein delipidation(GO:0051697) |
0.0 | 0.5 | GO:0046485 | ether lipid metabolic process(GO:0046485) |
0.0 | 5.0 | GO:0002377 | immunoglobulin production(GO:0002377) |
0.0 | 0.1 | GO:1901249 | regulation of lung goblet cell differentiation(GO:1901249) negative regulation of lung goblet cell differentiation(GO:1901250) |
0.0 | 0.3 | GO:0015727 | lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879) |
0.0 | 0.3 | GO:0018298 | protein-chromophore linkage(GO:0018298) |
0.0 | 1.5 | GO:0010862 | positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862) |
0.0 | 0.2 | GO:0097475 | motor neuron migration(GO:0097475) |
0.0 | 2.0 | GO:0002228 | natural killer cell mediated immunity(GO:0002228) |
0.0 | 0.9 | GO:0019731 | antibacterial humoral response(GO:0019731) |
0.0 | 0.1 | GO:1903334 | positive regulation of protein folding(GO:1903334) |
0.0 | 0.6 | GO:0060081 | membrane hyperpolarization(GO:0060081) |
0.0 | 4.3 | GO:0000187 | activation of MAPK activity(GO:0000187) |
0.0 | 0.1 | GO:0032329 | serine transport(GO:0032329) |
0.0 | 1.7 | GO:0007157 | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157) |
0.0 | 0.3 | GO:0099628 | receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628) |
0.0 | 0.4 | GO:0034391 | smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391) |
0.0 | 1.1 | GO:0045022 | early endosome to late endosome transport(GO:0045022) |
0.0 | 1.6 | GO:0051965 | positive regulation of synapse assembly(GO:0051965) |
0.0 | 0.4 | GO:0042492 | gamma-delta T cell differentiation(GO:0042492) |
0.0 | 2.8 | GO:0007586 | digestion(GO:0007586) |
0.0 | 0.2 | GO:0034058 | endosomal vesicle fusion(GO:0034058) |
0.0 | 0.7 | GO:0051560 | mitochondrial calcium ion homeostasis(GO:0051560) |
0.0 | 1.4 | GO:2000649 | regulation of sodium ion transmembrane transporter activity(GO:2000649) |
0.0 | 0.2 | GO:0030718 | germ-line stem cell population maintenance(GO:0030718) |
0.0 | 0.2 | GO:0051596 | methylglyoxal metabolic process(GO:0009438) methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727) |
0.0 | 0.2 | GO:0002098 | tRNA wobble uridine modification(GO:0002098) |
0.0 | 0.5 | GO:0030325 | adrenal gland development(GO:0030325) |
0.0 | 1.8 | GO:0046426 | negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893) |
0.0 | 0.5 | GO:0042832 | defense response to protozoan(GO:0042832) |
0.0 | 0.4 | GO:0032897 | negative regulation of viral transcription(GO:0032897) |
0.0 | 0.1 | GO:0018343 | protein farnesylation(GO:0018343) |
0.0 | 0.1 | GO:1904784 | NLRP1 inflammasome complex assembly(GO:1904784) |
0.0 | 0.1 | GO:0006546 | glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464) |
0.0 | 0.1 | GO:0034651 | cortisol biosynthetic process(GO:0034651) |
0.0 | 0.3 | GO:0007194 | negative regulation of adenylate cyclase activity(GO:0007194) |
0.0 | 0.3 | GO:0001921 | positive regulation of receptor recycling(GO:0001921) |
0.0 | 0.3 | GO:0016486 | peptide hormone processing(GO:0016486) |
0.0 | 0.2 | GO:1904424 | regulation of GTP binding(GO:1904424) |
0.0 | 0.1 | GO:0006290 | pyrimidine dimer repair(GO:0006290) |
0.0 | 0.2 | GO:0007220 | Notch receptor processing(GO:0007220) |
0.0 | 0.0 | GO:0045213 | neurotransmitter receptor metabolic process(GO:0045213) |
0.0 | 0.1 | GO:0051581 | negative regulation of neurotransmitter uptake(GO:0051581) negative regulation of serotonin uptake(GO:0051612) |
0.0 | 2.7 | GO:0006275 | regulation of DNA replication(GO:0006275) |
0.0 | 0.2 | GO:0019441 | tryptophan catabolic process(GO:0006569) tryptophan catabolic process to kynurenine(GO:0019441) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218) kynurenine metabolic process(GO:0070189) |
0.0 | 0.1 | GO:0060287 | epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287) |
0.0 | 0.1 | GO:0045347 | negative regulation of MHC class II biosynthetic process(GO:0045347) |
0.0 | 0.2 | GO:2000291 | regulation of myoblast proliferation(GO:2000291) |
0.0 | 0.1 | GO:1900364 | negative regulation of mRNA polyadenylation(GO:1900364) |
0.0 | 0.2 | GO:0048387 | negative regulation of retinoic acid receptor signaling pathway(GO:0048387) |
0.0 | 0.3 | GO:0015884 | folic acid transport(GO:0015884) |
0.0 | 0.8 | GO:0045454 | cell redox homeostasis(GO:0045454) |
0.0 | 0.6 | GO:0071300 | cellular response to retinoic acid(GO:0071300) |
0.0 | 0.3 | GO:0048013 | ephrin receptor signaling pathway(GO:0048013) |
0.0 | 0.5 | GO:0051693 | actin filament capping(GO:0051693) |
0.0 | 0.4 | GO:0050873 | brown fat cell differentiation(GO:0050873) |
0.0 | 0.1 | GO:0000185 | activation of MAPKKK activity(GO:0000185) |
0.0 | 0.1 | GO:0051152 | positive regulation of smooth muscle cell differentiation(GO:0051152) |
0.0 | 0.2 | GO:0010529 | regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529) |
0.0 | 0.7 | GO:0045600 | positive regulation of fat cell differentiation(GO:0045600) |
0.0 | 1.9 | GO:0042742 | defense response to bacterium(GO:0042742) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.7 | 2.0 | GO:0071149 | TEAD-2-YAP complex(GO:0071149) |
0.3 | 1.7 | GO:0071914 | prominosome(GO:0071914) |
0.2 | 0.9 | GO:0097447 | dendritic tree(GO:0097447) |
0.2 | 1.5 | GO:0097524 | sperm plasma membrane(GO:0097524) |
0.2 | 1.1 | GO:0070695 | FHF complex(GO:0070695) |
0.1 | 3.1 | GO:0042627 | chylomicron(GO:0042627) |
0.1 | 0.4 | GO:0031088 | platelet dense granule membrane(GO:0031088) |
0.1 | 0.9 | GO:0089717 | spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717) |
0.1 | 0.4 | GO:0005594 | collagen type IX trimer(GO:0005594) |
0.1 | 0.3 | GO:0031074 | nucleocytoplasmic shuttling complex(GO:0031074) nuclear RNA export factor complex(GO:0042272) |
0.1 | 0.3 | GO:0044307 | dendritic branch(GO:0044307) |
0.1 | 0.4 | GO:0036449 | microtubule minus-end(GO:0036449) |
0.1 | 0.4 | GO:0048237 | rough endoplasmic reticulum lumen(GO:0048237) |
0.1 | 0.5 | GO:0044352 | pinosome(GO:0044352) macropinosome(GO:0044354) |
0.1 | 0.7 | GO:0033180 | proton-transporting V-type ATPase, V1 domain(GO:0033180) |
0.1 | 1.3 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
0.1 | 0.8 | GO:0031258 | lamellipodium membrane(GO:0031258) |
0.1 | 0.6 | GO:0001739 | sex chromatin(GO:0001739) |
0.1 | 0.4 | GO:0005579 | membrane attack complex(GO:0005579) |
0.1 | 0.7 | GO:0033179 | proton-transporting V-type ATPase, V0 domain(GO:0033179) |
0.0 | 1.2 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
0.0 | 1.8 | GO:0016460 | myosin II complex(GO:0016460) |
0.0 | 0.2 | GO:1990032 | parallel fiber(GO:1990032) |
0.0 | 1.7 | GO:0008305 | integrin complex(GO:0008305) |
0.0 | 18.6 | GO:0005789 | endoplasmic reticulum membrane(GO:0005789) |
0.0 | 0.5 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
0.0 | 0.1 | GO:0005965 | protein farnesyltransferase complex(GO:0005965) |
0.0 | 0.2 | GO:0070765 | gamma-secretase complex(GO:0070765) |
0.0 | 1.3 | GO:0030131 | clathrin adaptor complex(GO:0030131) |
0.0 | 0.3 | GO:0005890 | sodium:potassium-exchanging ATPase complex(GO:0005890) |
0.0 | 2.2 | GO:0005844 | polysome(GO:0005844) |
0.0 | 0.2 | GO:0030897 | HOPS complex(GO:0030897) |
0.0 | 0.9 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
0.0 | 4.4 | GO:0072562 | blood microparticle(GO:0072562) |
0.0 | 0.2 | GO:0030478 | actin cap(GO:0030478) |
0.0 | 1.4 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
0.0 | 0.2 | GO:0070369 | beta-catenin-TCF7L2 complex(GO:0070369) |
0.0 | 0.1 | GO:0044316 | cone cell pedicle(GO:0044316) |
0.0 | 0.2 | GO:0030877 | beta-catenin destruction complex(GO:0030877) |
0.0 | 0.9 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
0.0 | 0.2 | GO:0097550 | transcriptional preinitiation complex(GO:0097550) |
0.0 | 0.5 | GO:0005605 | basal lamina(GO:0005605) |
0.0 | 0.6 | GO:0030057 | desmosome(GO:0030057) |
0.0 | 1.0 | GO:0016235 | aggresome(GO:0016235) |
0.0 | 2.4 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
0.0 | 1.7 | GO:0031526 | brush border membrane(GO:0031526) |
0.0 | 0.3 | GO:0044300 | cerebellar mossy fiber(GO:0044300) |
0.0 | 7.2 | GO:0030141 | secretory granule(GO:0030141) |
0.0 | 27.4 | GO:0005615 | extracellular space(GO:0005615) |
0.0 | 0.2 | GO:0031143 | pseudopodium(GO:0031143) |
0.0 | 0.2 | GO:0031080 | nuclear pore outer ring(GO:0031080) |
0.0 | 0.2 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
0.0 | 0.1 | GO:0072687 | meiotic spindle(GO:0072687) |
0.0 | 0.1 | GO:0042105 | alpha-beta T cell receptor complex(GO:0042105) |
0.0 | 0.3 | GO:0033268 | node of Ranvier(GO:0033268) |
0.0 | 0.1 | GO:0072558 | NLRP1 inflammasome complex(GO:0072558) |
0.0 | 0.2 | GO:0033655 | host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655) |
0.0 | 1.9 | GO:0090575 | RNA polymerase II transcription factor complex(GO:0090575) |
0.0 | 0.2 | GO:0016580 | Sin3 complex(GO:0016580) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.6 | 20.5 | GO:0050649 | testosterone 6-beta-hydroxylase activity(GO:0050649) |
1.0 | 7.0 | GO:0004027 | alcohol sulfotransferase activity(GO:0004027) |
0.8 | 2.3 | GO:0023030 | MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030) |
0.5 | 1.5 | GO:0047006 | 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006) |
0.4 | 1.3 | GO:0080130 | L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130) |
0.3 | 6.3 | GO:0070411 | I-SMAD binding(GO:0070411) |
0.3 | 2.5 | GO:0060228 | phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228) |
0.2 | 1.7 | GO:0001851 | complement component C3b binding(GO:0001851) |
0.2 | 0.6 | GO:0004911 | interleukin-2 receptor activity(GO:0004911) |
0.2 | 1.2 | GO:0008294 | calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294) |
0.2 | 2.5 | GO:0050544 | arachidonic acid binding(GO:0050544) |
0.2 | 0.9 | GO:0004062 | aryl sulfotransferase activity(GO:0004062) |
0.2 | 0.5 | GO:0005157 | macrophage colony-stimulating factor receptor binding(GO:0005157) |
0.1 | 1.5 | GO:0019957 | C-C chemokine binding(GO:0019957) |
0.1 | 0.8 | GO:0047184 | 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184) |
0.1 | 3.4 | GO:0008327 | methyl-CpG binding(GO:0008327) |
0.1 | 0.7 | GO:0050265 | RNA uridylyltransferase activity(GO:0050265) |
0.1 | 5.1 | GO:0015020 | glucuronosyltransferase activity(GO:0015020) |
0.1 | 3.1 | GO:0047555 | 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555) |
0.1 | 0.6 | GO:0060230 | lipoprotein lipase activator activity(GO:0060230) |
0.1 | 4.6 | GO:0043539 | protein serine/threonine kinase activator activity(GO:0043539) |
0.1 | 1.4 | GO:0015093 | ferrous iron transmembrane transporter activity(GO:0015093) |
0.1 | 23.1 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
0.1 | 0.4 | GO:0031708 | endothelin B receptor binding(GO:0031708) |
0.1 | 3.4 | GO:0008392 | arachidonic acid epoxygenase activity(GO:0008392) |
0.1 | 1.0 | GO:0015651 | quaternary ammonium group transmembrane transporter activity(GO:0015651) |
0.1 | 0.4 | GO:0005220 | inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220) |
0.1 | 0.7 | GO:0043423 | 3-phosphoinositide-dependent protein kinase binding(GO:0043423) |
0.1 | 0.4 | GO:0060072 | large conductance calcium-activated potassium channel activity(GO:0060072) |
0.1 | 0.3 | GO:0070401 | NADP+ binding(GO:0070401) |
0.1 | 1.9 | GO:0001134 | transcription factor activity, transcription factor recruiting(GO:0001134) |
0.1 | 0.2 | GO:0004461 | lactose synthase activity(GO:0004461) |
0.1 | 0.9 | GO:0102336 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
0.1 | 1.6 | GO:0070016 | armadillo repeat domain binding(GO:0070016) |
0.1 | 0.9 | GO:0008429 | phosphatidylethanolamine binding(GO:0008429) |
0.1 | 0.5 | GO:0002054 | nucleobase binding(GO:0002054) |
0.1 | 0.3 | GO:0047710 | bis(5'-adenosyl)-triphosphatase activity(GO:0047710) |
0.1 | 3.8 | GO:0008146 | sulfotransferase activity(GO:0008146) |
0.1 | 0.2 | GO:0047522 | 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522) |
0.1 | 1.1 | GO:0031005 | filamin binding(GO:0031005) |
0.1 | 1.7 | GO:0004190 | aspartic-type endopeptidase activity(GO:0004190) |
0.1 | 0.8 | GO:0043855 | cyclic nucleotide-gated ion channel activity(GO:0043855) |
0.1 | 8.6 | GO:0008083 | growth factor activity(GO:0008083) |
0.1 | 0.9 | GO:0016500 | protein-hormone receptor activity(GO:0016500) |
0.1 | 0.3 | GO:0004111 | creatine kinase activity(GO:0004111) |
0.1 | 0.2 | GO:0000700 | mismatch base pair DNA N-glycosylase activity(GO:0000700) |
0.1 | 0.5 | GO:0000268 | peroxisome targeting sequence binding(GO:0000268) |
0.1 | 0.2 | GO:0033754 | indoleamine 2,3-dioxygenase activity(GO:0033754) |
0.1 | 1.4 | GO:0046961 | proton-transporting ATPase activity, rotational mechanism(GO:0046961) |
0.0 | 3.3 | GO:0042805 | actinin binding(GO:0042805) |
0.0 | 1.3 | GO:0000146 | microfilament motor activity(GO:0000146) |
0.0 | 0.7 | GO:0045028 | G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028) |
0.0 | 0.3 | GO:0070883 | pre-miRNA binding(GO:0070883) |
0.0 | 0.6 | GO:0005436 | sodium:phosphate symporter activity(GO:0005436) |
0.0 | 0.6 | GO:0050308 | sugar-phosphatase activity(GO:0050308) |
0.0 | 0.3 | GO:0031812 | G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812) |
0.0 | 0.2 | GO:0003836 | beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836) |
0.0 | 0.2 | GO:0016300 | tRNA (uracil) methyltransferase activity(GO:0016300) |
0.0 | 0.2 | GO:0004952 | dopamine neurotransmitter receptor activity(GO:0004952) |
0.0 | 0.2 | GO:0047844 | deoxycytidine deaminase activity(GO:0047844) |
0.0 | 0.7 | GO:0004806 | triglyceride lipase activity(GO:0004806) |
0.0 | 0.3 | GO:0061578 | Lys63-specific deubiquitinase activity(GO:0061578) |
0.0 | 1.5 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
0.0 | 0.1 | GO:0004660 | protein farnesyltransferase activity(GO:0004660) |
0.0 | 3.2 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
0.0 | 0.2 | GO:0035662 | Toll-like receptor 4 binding(GO:0035662) |
0.0 | 0.2 | GO:0004416 | hydroxyacylglutathione hydrolase activity(GO:0004416) |
0.0 | 0.3 | GO:0043008 | ATP-dependent protein binding(GO:0043008) |
0.0 | 0.1 | GO:0004534 | 5'-3' exoribonuclease activity(GO:0004534) |
0.0 | 0.3 | GO:0051870 | methotrexate binding(GO:0051870) |
0.0 | 1.2 | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547) |
0.0 | 1.0 | GO:0051959 | dynein light intermediate chain binding(GO:0051959) |
0.0 | 0.3 | GO:0019911 | structural constituent of myelin sheath(GO:0019911) |
0.0 | 0.2 | GO:0015181 | arginine transmembrane transporter activity(GO:0015181) |
0.0 | 0.2 | GO:0035033 | histone deacetylase regulator activity(GO:0035033) |
0.0 | 0.3 | GO:0038191 | neuropilin binding(GO:0038191) |
0.0 | 1.2 | GO:0070888 | E-box binding(GO:0070888) |
0.0 | 0.2 | GO:1901611 | phosphatidylglycerol binding(GO:1901611) |
0.0 | 0.3 | GO:0019865 | immunoglobulin binding(GO:0019865) |
0.0 | 0.7 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
0.0 | 0.5 | GO:0005351 | sugar:proton symporter activity(GO:0005351) |
0.0 | 0.4 | GO:0016854 | racemase and epimerase activity(GO:0016854) |
0.0 | 0.5 | GO:0005031 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
0.0 | 0.9 | GO:0046875 | ephrin receptor binding(GO:0046875) |
0.0 | 0.1 | GO:0030550 | acetylcholine receptor inhibitor activity(GO:0030550) |
0.0 | 0.2 | GO:0008409 | 5'-3' exonuclease activity(GO:0008409) |
0.0 | 0.7 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
0.0 | 2.8 | GO:0051015 | actin filament binding(GO:0051015) |
0.0 | 0.1 | GO:0031995 | insulin-like growth factor II binding(GO:0031995) |
0.0 | 1.1 | GO:0004197 | cysteine-type endopeptidase activity(GO:0004197) |
0.0 | 0.2 | GO:0004185 | serine-type carboxypeptidase activity(GO:0004185) serine-type exopeptidase activity(GO:0070008) |
0.0 | 0.0 | GO:0004104 | cholinesterase activity(GO:0004104) |
0.0 | 0.1 | GO:0055131 | C3HC4-type RING finger domain binding(GO:0055131) |
0.0 | 0.3 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
0.0 | 0.2 | GO:0032454 | histone demethylase activity (H3-K9 specific)(GO:0032454) |
0.0 | 3.0 | GO:0030246 | carbohydrate binding(GO:0030246) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 6.5 | PID BETA CATENIN DEG PATHWAY | Degradation of beta catenin |
0.1 | 3.0 | ST WNT CA2 CYCLIC GMP PATHWAY | Wnt/Ca2+/cyclic GMP signaling. |
0.1 | 6.4 | PID AJDISS 2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
0.1 | 2.3 | PID WNT NONCANONICAL PATHWAY | Noncanonical Wnt signaling pathway |
0.1 | 2.8 | PID SYNDECAN 4 PATHWAY | Syndecan-4-mediated signaling events |
0.1 | 1.2 | PID LPA4 PATHWAY | LPA4-mediated signaling events |
0.1 | 1.7 | PID INTEGRIN2 PATHWAY | Beta2 integrin cell surface interactions |
0.0 | 0.8 | PID ANTHRAX PATHWAY | Cellular roles of Anthrax toxin |
0.0 | 1.2 | PID ARF6 PATHWAY | Arf6 signaling events |
0.0 | 1.3 | PID ER NONGENOMIC PATHWAY | Plasma membrane estrogen receptor signaling |
0.0 | 0.6 | PID EPHRINB REV PATHWAY | Ephrin B reverse signaling |
0.0 | 1.4 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
0.0 | 1.0 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
0.0 | 0.2 | PID SYNDECAN 3 PATHWAY | Syndecan-3-mediated signaling events |
0.0 | 0.7 | PID FOXM1 PATHWAY | FOXM1 transcription factor network |
0.0 | 0.6 | PID IL2 PI3K PATHWAY | IL2 signaling events mediated by PI3K |
0.0 | 0.5 | PID P38 MK2 PATHWAY | p38 signaling mediated by MAPKAP kinases |
0.0 | 0.5 | PID FOXO PATHWAY | FoxO family signaling |
0.0 | 0.4 | PID ENDOTHELIN PATHWAY | Endothelins |
0.0 | 0.6 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
0.0 | 0.4 | ST TUMOR NECROSIS FACTOR PATHWAY | Tumor Necrosis Factor Pathway. |
0.0 | 0.3 | ST GA12 PATHWAY | G alpha 12 Pathway |
0.0 | 0.8 | PID RAC1 REG PATHWAY | Regulation of RAC1 activity |
0.0 | 0.4 | PID HIF2PATHWAY | HIF-2-alpha transcription factor network |
0.0 | 1.2 | PID CMYB PATHWAY | C-MYB transcription factor network |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 1.5 | REACTOME BETA DEFENSINS | Genes involved in Beta defensins |
0.2 | 3.2 | REACTOME GLUCURONIDATION | Genes involved in Glucuronidation |
0.2 | 4.6 | REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
0.2 | 1.5 | REACTOME GLYCOPROTEIN HORMONES | Genes involved in Glycoprotein hormones |
0.1 | 0.3 | REACTOME PEPTIDE HORMONE BIOSYNTHESIS | Genes involved in Peptide hormone biosynthesis |
0.1 | 3.2 | REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX | Genes involved in Degradation of the extracellular matrix |
0.1 | 0.5 | REACTOME DEFENSINS | Genes involved in Defensins |
0.1 | 1.4 | REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN | Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin |
0.1 | 1.2 | REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY | Genes involved in Adenylate cyclase activating pathway |
0.1 | 4.0 | REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
0.1 | 1.0 | REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT | Genes involved in Organic cation/anion/zwitterion transport |
0.1 | 0.7 | REACTOME P2Y RECEPTORS | Genes involved in P2Y receptors |
0.0 | 1.4 | REACTOME INSULIN RECEPTOR RECYCLING | Genes involved in Insulin receptor recycling |
0.0 | 1.9 | REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION | Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression |
0.0 | 1.0 | REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS | Genes involved in ABCA transporters in lipid homeostasis |
0.0 | 0.6 | REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL | Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol |
0.0 | 0.9 | REACTOME ALPHA LINOLENIC ACID ALA METABOLISM | Genes involved in alpha-linolenic acid (ALA) metabolism |
0.0 | 0.8 | REACTOME ACYL CHAIN REMODELLING OF PC | Genes involved in Acyl chain remodelling of PC |
0.0 | 2.5 | REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |
0.0 | 0.5 | REACTOME PYRIMIDINE CATABOLISM | Genes involved in Pyrimidine catabolism |
0.0 | 4.6 | REACTOME PEPTIDE LIGAND BINDING RECEPTORS | Genes involved in Peptide ligand-binding receptors |
0.0 | 0.9 | REACTOME SYNTHESIS OF PC | Genes involved in Synthesis of PC |
0.0 | 0.7 | REACTOME ZINC TRANSPORTERS | Genes involved in Zinc transporters |
0.0 | 1.3 | REACTOME STRIATED MUSCLE CONTRACTION | Genes involved in Striated Muscle Contraction |
0.0 | 0.1 | REACTOME ACTIVATION OF NF KAPPAB IN B CELLS | Genes involved in Activation of NF-kappaB in B Cells |
0.0 | 0.2 | REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY | Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway |
0.0 | 0.2 | REACTOME REGULATED PROTEOLYSIS OF P75NTR | Genes involved in Regulated proteolysis of p75NTR |
0.0 | 0.2 | REACTOME COPI MEDIATED TRANSPORT | Genes involved in COPI Mediated Transport |
0.0 | 0.3 | REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION | Genes involved in Unblocking of NMDA receptor, glutamate binding and activation |
0.0 | 1.4 | REACTOME INTEGRIN CELL SURFACE INTERACTIONS | Genes involved in Integrin cell surface interactions |
0.0 | 0.6 | REACTOME IL RECEPTOR SHC SIGNALING | Genes involved in Interleukin receptor SHC signaling |
0.0 | 2.7 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
0.0 | 0.3 | REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS | Genes involved in Trafficking of GluR2-containing AMPA receptors |
0.0 | 0.7 | REACTOME LIPID DIGESTION MOBILIZATION AND TRANSPORT | Genes involved in Lipid digestion, mobilization, and transport |
0.0 | 0.4 | REACTOME CA DEPENDENT EVENTS | Genes involved in Ca-dependent events |
0.0 | 0.2 | REACTOME CTNNB1 PHOSPHORYLATION CASCADE | Genes involved in Beta-catenin phosphorylation cascade |
0.0 | 0.3 | REACTOME MICRORNA MIRNA BIOGENESIS | Genes involved in MicroRNA (miRNA) Biogenesis |
0.0 | 0.6 | REACTOME VOLTAGE GATED POTASSIUM CHANNELS | Genes involved in Voltage gated Potassium channels |
0.0 | 0.2 | REACTOME MUSCLE CONTRACTION | Genes involved in Muscle contraction |
0.0 | 0.5 | REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES | Genes involved in Transport of vitamins, nucleosides, and related molecules |