Project

avrg: GSE58827: Dynamics of the Mouse Liver

Navigation
Downloads

Results for Foxd2

Z-value: 0.60

Motif logo

Transcription factors associated with Foxd2

Gene Symbol Gene ID Gene Info
ENSMUSG00000055210.3 forkhead box D2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Foxd2mm10_v2_chr4_-_114908892_1149089140.298.3e-02Click!

Activity profile of Foxd2 motif

Sorted Z-values of Foxd2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Foxd2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0035585 calcium-mediated signaling using extracellular calcium source(GO:0035585)
0.4 1.7 GO:1901580 post-embryonic appendage morphogenesis(GO:0035120) post-embryonic limb morphogenesis(GO:0035127) post-embryonic forelimb morphogenesis(GO:0035128) telomeric repeat-containing RNA transcription(GO:0097393) telomeric repeat-containing RNA transcription from RNA pol II promoter(GO:0097394) regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901580) negative regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901581) positive regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901582)
0.3 1.7 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.3 2.2 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.3 0.8 GO:0034165 positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
0.2 2.0 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.2 0.9 GO:0015827 aromatic amino acid transport(GO:0015801) tryptophan transport(GO:0015827)
0.2 3.8 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.2 0.9 GO:1902608 negative regulation of inositol phosphate biosynthetic process(GO:0010920) regulation of large conductance calcium-activated potassium channel activity(GO:1902606) positive regulation of large conductance calcium-activated potassium channel activity(GO:1902608)
0.2 0.5 GO:0032685 negative regulation of granulocyte macrophage colony-stimulating factor production(GO:0032685)
0.1 1.0 GO:0034144 negative regulation of toll-like receptor 4 signaling pathway(GO:0034144)
0.1 0.8 GO:0035811 negative regulation of urine volume(GO:0035811)
0.1 0.3 GO:0034148 regulation of granuloma formation(GO:0002631) negative regulation of granuloma formation(GO:0002632) regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433) tolerance induction to lipopolysaccharide(GO:0072573)
0.1 0.6 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.1 0.8 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.1 1.7 GO:0034587 piRNA metabolic process(GO:0034587)
0.1 0.7 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.1 1.3 GO:0006968 cellular defense response(GO:0006968)
0.1 1.1 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.1 1.0 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.1 0.9 GO:0046541 saliva secretion(GO:0046541)
0.1 0.2 GO:2000584 regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.1 0.6 GO:0070431 nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423) nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070431)
0.1 0.6 GO:0051026 chiasma assembly(GO:0051026)
0.0 0.5 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.4 GO:0010757 regulation of blood vessel size by renin-angiotensin(GO:0002034) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072) negative regulation of plasminogen activation(GO:0010757)
0.0 2.3 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0 0.4 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.0 0.5 GO:2000270 positive regulation of transcription from RNA polymerase III promoter(GO:0045945) negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.3 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.2 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.5 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.2 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0 1.9 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.0 0.4 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.4 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.4 GO:0060046 regulation of acrosome reaction(GO:0060046)
0.0 0.1 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0 0.3 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.6 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.7 GO:0030819 positive regulation of cAMP biosynthetic process(GO:0030819)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.8 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.5 2.1 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.4 1.7 GO:1990707 subtelomeric heterochromatin(GO:1990421) nuclear subtelomeric heterochromatin(GO:1990707)
0.3 1.7 GO:0071547 piP-body(GO:0071547)
0.2 2.3 GO:0042581 specific granule(GO:0042581)
0.1 0.4 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.2 GO:0045160 myosin I complex(GO:0045160)
0.0 1.1 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.4 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.8 GO:0031528 guanylate cyclase complex, soluble(GO:0008074) microvillus membrane(GO:0031528)
0.0 0.5 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.3 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.9 GO:0043034 costamere(GO:0043034)
0.0 0.5 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0045352 interleukin-1, Type II receptor binding(GO:0005151) interleukin-1 Type I receptor antagonist activity(GO:0045352) interleukin-1 Type II receptor antagonist activity(GO:0045353)
0.2 1.7 GO:0015616 DNA translocase activity(GO:0015616)
0.2 0.9 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.1 0.8 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.1 0.9 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.1 0.7 GO:0004977 melanocortin receptor activity(GO:0004977)
0.1 0.9 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.6 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 3.8 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 0.9 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 0.6 GO:0030983 mismatched DNA binding(GO:0030983)
0.1 0.2 GO:0034617 tetrahydrobiopterin binding(GO:0034617)
0.1 0.3 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 0.5 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.1 1.1 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.8 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 2.9 GO:0043621 protein self-association(GO:0043621)
0.0 4.2 GO:0005179 hormone activity(GO:0005179)
0.0 0.1 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.2 GO:0004027 alcohol sulfotransferase activity(GO:0004027)
0.0 0.5 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.5 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 1.7 GO:0004004 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.1 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.0 0.4 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.1 GO:0097003 adipokinetic hormone receptor activity(GO:0097003)
0.0 0.1 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.0 0.6 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.7 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 1.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.8 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.7 GO:0016860 intramolecular oxidoreductase activity(GO:0016860)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 2.1 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.7 PID IL1 PATHWAY IL1-mediated signaling events
0.0 1.0 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.9 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 1.3 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.0 4.3 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.8 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.3 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.2 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 0.8 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.1 2.0 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 2.0 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.9 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 1.6 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.9 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.7 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 1.1 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.3 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway