avrg: GSE58827: Dynamics of the Mouse Liver
Gene Symbol | Gene ID | Gene Info |
---|---|---|
Aire
|
ENSMUSG00000000731.9 | autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy) |
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Aire | mm10_v2_chr10_-_78043580_78043611 | -0.04 | 8.3e-01 | Click! |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 1.3 | GO:0042853 | glycine biosynthetic process, by transamination of glyoxylate(GO:0019265) L-alanine catabolic process(GO:0042853) |
0.4 | 1.5 | GO:0032789 | saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789) |
0.3 | 1.3 | GO:0061625 | fructose catabolic process(GO:0006001) response to sucrose(GO:0009744) response to disaccharide(GO:0034285) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) glycolytic process through fructose-1-phosphate(GO:0061625) |
0.3 | 0.8 | GO:0018214 | peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214) |
0.2 | 0.6 | GO:2000170 | positive regulation of peptidyl-cysteine S-nitrosylation(GO:2000170) |
0.2 | 0.5 | GO:0006550 | isoleucine catabolic process(GO:0006550) |
0.2 | 0.7 | GO:0016340 | calcium-dependent cell-matrix adhesion(GO:0016340) |
0.1 | 0.9 | GO:0002248 | connective tissue replacement involved in inflammatory response wound healing(GO:0002248) |
0.1 | 1.5 | GO:0052697 | flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697) |
0.1 | 0.5 | GO:0006742 | NADP catabolic process(GO:0006742) |
0.1 | 1.1 | GO:0098706 | ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706) |
0.1 | 0.8 | GO:0032020 | ISG15-protein conjugation(GO:0032020) |
0.1 | 0.3 | GO:0042726 | flavin-containing compound metabolic process(GO:0042726) |
0.1 | 1.5 | GO:0009437 | carnitine metabolic process(GO:0009437) |
0.1 | 0.3 | GO:0006097 | glyoxylate cycle(GO:0006097) |
0.1 | 0.5 | GO:0061056 | sclerotome development(GO:0061056) |
0.1 | 0.5 | GO:0033762 | response to glucagon(GO:0033762) |
0.1 | 2.6 | GO:0019373 | epoxygenase P450 pathway(GO:0019373) |
0.1 | 0.5 | GO:0071376 | response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376) |
0.1 | 0.4 | GO:0009115 | xanthine catabolic process(GO:0009115) |
0.1 | 0.7 | GO:0008300 | isoprenoid catabolic process(GO:0008300) |
0.1 | 0.4 | GO:1904491 | protein localization to ciliary transition zone(GO:1904491) |
0.0 | 0.1 | GO:0000715 | nucleotide-excision repair, DNA damage recognition(GO:0000715) |
0.0 | 0.5 | GO:0086023 | adrenergic receptor signaling pathway involved in heart process(GO:0086023) |
0.0 | 0.9 | GO:0001580 | detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580) |
0.0 | 0.4 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
0.0 | 0.2 | GO:0035726 | common myeloid progenitor cell proliferation(GO:0035726) |
0.0 | 1.9 | GO:1900047 | negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047) |
0.0 | 1.0 | GO:0048240 | sperm capacitation(GO:0048240) |
0.0 | 0.3 | GO:1902572 | regulation of serine-type endopeptidase activity(GO:1900003) negative regulation of serine-type endopeptidase activity(GO:1900004) regulation of serine-type peptidase activity(GO:1902571) negative regulation of serine-type peptidase activity(GO:1902572) |
0.0 | 0.4 | GO:0046485 | ether lipid metabolic process(GO:0046485) |
0.0 | 0.1 | GO:0002430 | complement receptor mediated signaling pathway(GO:0002430) |
0.0 | 1.4 | GO:0042773 | ATP synthesis coupled electron transport(GO:0042773) |
0.0 | 0.6 | GO:0015813 | L-glutamate transport(GO:0015813) |
0.0 | 0.4 | GO:2000480 | negative regulation of cAMP-dependent protein kinase activity(GO:2000480) |
0.0 | 1.6 | GO:2001238 | positive regulation of extrinsic apoptotic signaling pathway(GO:2001238) |
0.0 | 0.1 | GO:0030974 | thiamine pyrophosphate transport(GO:0030974) |
0.0 | 1.4 | GO:0006749 | glutathione metabolic process(GO:0006749) |
0.0 | 0.2 | GO:0016191 | synaptic vesicle uncoating(GO:0016191) |
0.0 | 0.5 | GO:0015985 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
0.0 | 0.3 | GO:0022904 | respiratory electron transport chain(GO:0022904) |
0.0 | 0.1 | GO:0035553 | oxidative single-stranded DNA demethylation(GO:0035552) oxidative single-stranded RNA demethylation(GO:0035553) |
0.0 | 0.2 | GO:1902414 | protein localization to cell junction(GO:1902414) |
0.0 | 0.2 | GO:0090110 | cargo loading into COPII-coated vesicle(GO:0090110) |
0.0 | 0.2 | GO:0007221 | positive regulation of transcription of Notch receptor target(GO:0007221) |
0.0 | 0.5 | GO:2000398 | regulation of T cell differentiation in thymus(GO:0033081) regulation of thymocyte aggregation(GO:2000398) |
0.0 | 0.1 | GO:0016560 | protein import into peroxisome matrix, docking(GO:0016560) |
0.0 | 0.1 | GO:0007168 | receptor guanylyl cyclase signaling pathway(GO:0007168) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 0.9 | GO:0036128 | CatSper complex(GO:0036128) |
0.1 | 0.7 | GO:0016011 | dystroglycan complex(GO:0016011) |
0.1 | 2.1 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
0.0 | 0.9 | GO:0005751 | mitochondrial respiratory chain complex IV(GO:0005751) |
0.0 | 0.5 | GO:0045275 | respiratory chain complex III(GO:0045275) |
0.0 | 1.2 | GO:0031307 | integral component of mitochondrial outer membrane(GO:0031307) |
0.0 | 0.5 | GO:0000276 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) |
0.0 | 0.1 | GO:0071942 | XPC complex(GO:0071942) |
0.0 | 0.4 | GO:0036038 | MKS complex(GO:0036038) |
0.0 | 0.4 | GO:0042555 | MCM complex(GO:0042555) |
0.0 | 0.6 | GO:0097225 | sperm midpiece(GO:0097225) |
0.0 | 0.1 | GO:0097598 | sperm cytoplasmic droplet(GO:0097598) |
0.0 | 0.2 | GO:0097208 | alveolar lamellar body(GO:0097208) |
0.0 | 4.4 | GO:0005777 | peroxisome(GO:0005777) microbody(GO:0042579) |
0.0 | 0.3 | GO:0098563 | integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563) |
0.0 | 1.0 | GO:0070469 | respiratory chain(GO:0070469) |
0.0 | 0.1 | GO:0033647 | host intracellular organelle(GO:0033647) host intracellular membrane-bounded organelle(GO:0033648) |
0.0 | 0.1 | GO:0005787 | signal peptidase complex(GO:0005787) |
0.0 | 0.2 | GO:0030127 | COPII vesicle coat(GO:0030127) |
0.0 | 1.9 | GO:0072562 | blood microparticle(GO:0072562) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 1.3 | GO:0004454 | ketohexokinase activity(GO:0004454) |
0.4 | 2.6 | GO:0034875 | oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875) |
0.4 | 1.1 | GO:0003987 | acetate-CoA ligase activity(GO:0003987) |
0.2 | 1.2 | GO:0016416 | carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416) |
0.2 | 1.3 | GO:0008453 | alanine-glyoxylate transaminase activity(GO:0008453) |
0.1 | 0.6 | GO:0031711 | tripeptidyl-peptidase activity(GO:0008240) bradykinin receptor binding(GO:0031711) metallodipeptidase activity(GO:0070573) |
0.1 | 0.8 | GO:0042296 | ISG15 transferase activity(GO:0042296) |
0.1 | 1.1 | GO:0008823 | cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851) |
0.1 | 0.4 | GO:0050479 | glyceryl-ether monooxygenase activity(GO:0050479) |
0.1 | 0.5 | GO:0016453 | acetyl-CoA C-acetyltransferase activity(GO:0003985) C-acetyltransferase activity(GO:0016453) |
0.1 | 0.3 | GO:0004450 | isocitrate dehydrogenase (NADP+) activity(GO:0004450) |
0.1 | 3.2 | GO:0015020 | glucuronosyltransferase activity(GO:0015020) |
0.1 | 0.5 | GO:0042030 | ATPase inhibitor activity(GO:0042030) |
0.1 | 0.5 | GO:0035529 | NADH pyrophosphatase activity(GO:0035529) |
0.1 | 0.3 | GO:0004466 | long-chain-acyl-CoA dehydrogenase activity(GO:0004466) palmitoyl-CoA oxidase activity(GO:0016401) |
0.1 | 1.5 | GO:0016290 | palmitoyl-CoA hydrolase activity(GO:0016290) |
0.1 | 0.4 | GO:0016726 | xanthine dehydrogenase activity(GO:0004854) oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor(GO:0016726) |
0.1 | 0.7 | GO:0043237 | laminin-1 binding(GO:0043237) |
0.1 | 0.5 | GO:0008121 | ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681) |
0.1 | 0.3 | GO:0070052 | collagen V binding(GO:0070052) |
0.1 | 1.4 | GO:0015035 | protein disulfide oxidoreductase activity(GO:0015035) |
0.1 | 0.3 | GO:0032450 | maltose alpha-glucosidase activity(GO:0032450) |
0.0 | 0.6 | GO:0005314 | high-affinity glutamate transmembrane transporter activity(GO:0005314) |
0.0 | 0.8 | GO:0048038 | quinone binding(GO:0048038) |
0.0 | 1.2 | GO:0016676 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
0.0 | 1.0 | GO:0008137 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
0.0 | 1.3 | GO:0005520 | insulin-like growth factor binding(GO:0005520) |
0.0 | 0.7 | GO:0016854 | racemase and epimerase activity(GO:0016854) |
0.0 | 1.3 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
0.0 | 0.2 | GO:0047631 | ADP-ribose diphosphatase activity(GO:0047631) |
0.0 | 0.1 | GO:0005124 | scavenger receptor binding(GO:0005124) |
0.0 | 0.2 | GO:0017162 | aryl hydrocarbon receptor binding(GO:0017162) |
0.0 | 0.1 | GO:0051747 | cytosine C-5 DNA demethylase activity(GO:0051747) |
0.0 | 0.3 | GO:0008553 | hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553) |
0.0 | 0.4 | GO:0004862 | cAMP-dependent protein kinase inhibitor activity(GO:0004862) |
0.0 | 0.1 | GO:0005052 | peroxisome matrix targeting signal-1 binding(GO:0005052) |
0.0 | 0.5 | GO:0035259 | glucocorticoid receptor binding(GO:0035259) |
0.0 | 0.4 | GO:0070566 | adenylyltransferase activity(GO:0070566) |
0.0 | 1.0 | GO:0004869 | cysteine-type endopeptidase inhibitor activity(GO:0004869) |
0.0 | 0.1 | GO:0015234 | thiamine transmembrane transporter activity(GO:0015234) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 0.7 | ST PAC1 RECEPTOR PATHWAY | PAC1 Receptor Pathway |
0.0 | 0.6 | SA MMP CYTOKINE CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
0.0 | 0.7 | PID INTEGRIN2 PATHWAY | Beta2 integrin cell surface interactions |
0.0 | 1.2 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
0.0 | 0.4 | ST MYOCYTE AD PATHWAY | Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway. |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 0.3 | REACTOME DIGESTION OF DIETARY CARBOHYDRATE | Genes involved in Digestion of dietary carbohydrate |
0.1 | 1.3 | REACTOME PYRIMIDINE CATABOLISM | Genes involved in Pyrimidine catabolism |
0.1 | 0.8 | REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS | Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins |
0.1 | 0.7 | REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL | Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol |
0.0 | 1.2 | REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE | Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle |
0.0 | 0.4 | REACTOME PURINE CATABOLISM | Genes involved in Purine catabolism |
0.0 | 0.7 | REACTOME INTRINSIC PATHWAY | Genes involved in Intrinsic Pathway |
0.0 | 0.5 | REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
0.0 | 0.4 | REACTOME UNWINDING OF DNA | Genes involved in Unwinding of DNA |
0.0 | 0.3 | REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION | Genes involved in Mitochondrial Fatty Acid Beta-Oxidation |
0.0 | 0.3 | REACTOME INSULIN RECEPTOR RECYCLING | Genes involved in Insulin receptor recycling |
0.0 | 0.2 | REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC | Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC |