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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Homez

Z-value: 1.44

Motif logo

Transcription factors associated with Homez

Gene Symbol Gene ID Gene Info
ENSMUSG00000057156.9 homeodomain leucine zipper-encoding gene

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Homezmm10_v2_chr14_-_54864055_54864158-0.464.7e-03Click!

Activity profile of Homez motif

Sorted Z-values of Homez motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Homez

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.6 3.1 GO:0001692 histamine metabolic process(GO:0001692)
0.4 1.5 GO:0006069 ethanol oxidation(GO:0006069)
0.3 4.5 GO:0015747 urate transport(GO:0015747)
0.3 1.2 GO:0000711 meiotic DNA repair synthesis(GO:0000711) female meiosis sister chromatid cohesion(GO:0007066)
0.3 0.9 GO:0097274 urea homeostasis(GO:0097274)
0.3 1.5 GO:0070178 D-serine metabolic process(GO:0070178)
0.3 0.8 GO:1904719 excitatory chemical synaptic transmission(GO:0098976) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.3 1.1 GO:0042197 chlorinated hydrocarbon metabolic process(GO:0042196) halogenated hydrocarbon metabolic process(GO:0042197)
0.3 1.0 GO:0036233 glycine import(GO:0036233)
0.2 0.9 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.2 0.8 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.2 0.6 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.2 1.1 GO:1903751 regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
0.2 0.9 GO:0006741 NADP biosynthetic process(GO:0006741)
0.1 0.4 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.1 1.0 GO:0018158 protein oxidation(GO:0018158)
0.1 0.4 GO:0048209 regulation of vesicle targeting, to, from or within Golgi(GO:0048209)
0.1 0.5 GO:0001827 inner cell mass cell fate commitment(GO:0001827) positive regulation of sperm motility(GO:1902093)
0.1 0.8 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.1 0.4 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.1 1.1 GO:0071569 protein ufmylation(GO:0071569)
0.1 0.4 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.1 0.7 GO:0061113 pancreas morphogenesis(GO:0061113)
0.1 0.3 GO:0030573 bile acid catabolic process(GO:0030573)
0.1 2.9 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.1 0.3 GO:0009804 coumarin metabolic process(GO:0009804) phenylpropanoid catabolic process(GO:0046271)
0.1 0.8 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729)
0.1 0.4 GO:1904970 brush border assembly(GO:1904970)
0.1 0.3 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.1 1.2 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.1 0.7 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.1 0.2 GO:0033577 protein glycosylation in endoplasmic reticulum(GO:0033577)
0.1 0.4 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.1 0.4 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.1 0.5 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.1 0.4 GO:0046502 uroporphyrinogen III metabolic process(GO:0046502)
0.1 0.3 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.1 0.3 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.1 0.5 GO:0042126 nitrate metabolic process(GO:0042126)
0.1 0.9 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1 0.1 GO:0007172 signal complex assembly(GO:0007172)
0.1 0.7 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.1 0.3 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.1 0.7 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.1 0.4 GO:0042559 pteridine-containing compound biosynthetic process(GO:0042559)
0.1 1.1 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.1 0.3 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.1 0.6 GO:1901387 positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.1 0.2 GO:0051030 snRNA transport(GO:0051030)
0.1 0.5 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 1.3 GO:0032402 melanosome transport(GO:0032402)
0.0 0.3 GO:0043634 polyadenylation-dependent ncRNA catabolic process(GO:0043634)
0.0 0.8 GO:0045199 maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0 0.1 GO:0090118 receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118)
0.0 0.5 GO:0070836 caveola assembly(GO:0070836)
0.0 0.4 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.3 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.0 0.2 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.0 1.0 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.8 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.0 0.1 GO:0006434 seryl-tRNA aminoacylation(GO:0006434) negative regulation of vascular endothelial growth factor production(GO:1904046)
0.0 0.2 GO:0006382 adenosine to inosine editing(GO:0006382) regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
0.0 0.6 GO:0006968 cellular defense response(GO:0006968)
0.0 0.3 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.5 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 0.8 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.1 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.4 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 1.9 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.0 0.1 GO:0046104 thymidine metabolic process(GO:0046104)
0.0 0.5 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.3 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.4 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.4 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.5 GO:0035404 histone-serine phosphorylation(GO:0035404)
0.0 0.1 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
0.0 0.2 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.2 GO:1901098 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335) positive regulation of autophagosome maturation(GO:1901098)
0.0 0.1 GO:0043102 amino acid salvage(GO:0043102) L-methionine salvage(GO:0071267)
0.0 0.1 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.0 0.8 GO:0019236 response to pheromone(GO:0019236)
0.0 0.2 GO:0061143 alveolar primary septum development(GO:0061143)
0.0 0.3 GO:0010820 positive regulation of T cell chemotaxis(GO:0010820)
0.0 0.2 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0 0.2 GO:0098719 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.7 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 1.1 GO:0046825 regulation of protein export from nucleus(GO:0046825)
0.0 0.1 GO:0048686 regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)
0.0 0.3 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.3 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.1 GO:0002270 plasmacytoid dendritic cell activation(GO:0002270)
0.0 0.9 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.6 GO:0007020 microtubule nucleation(GO:0007020)
0.0 0.5 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.0 0.2 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.0 0.1 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.3 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.0 0.4 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.0 0.2 GO:0051103 DNA ligation involved in DNA repair(GO:0051103)
0.0 0.9 GO:0046902 regulation of mitochondrial membrane permeability(GO:0046902)
0.0 0.3 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.3 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 2.5 GO:0009308 amine metabolic process(GO:0009308)
0.0 0.2 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.0 0.8 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.0 0.4 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.5 GO:0015893 drug transport(GO:0015893)
0.0 0.1 GO:0051255 spindle midzone assembly(GO:0051255)
0.0 0.1 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.0 0.8 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.2 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.2 GO:0006515 misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.0 0.1 GO:1901629 regulation of presynaptic membrane organization(GO:1901629)
0.0 0.6 GO:1901264 carbohydrate derivative transport(GO:1901264)
0.0 1.1 GO:0048663 neuron fate commitment(GO:0048663)
0.0 0.0 GO:0051176 positive regulation of sulfur metabolic process(GO:0051176)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 GO:0000802 transverse filament(GO:0000802)
0.3 0.9 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.3 2.9 GO:0070545 PeBoW complex(GO:0070545)
0.1 0.8 GO:0071817 MMXD complex(GO:0071817)
0.1 1.4 GO:0005579 membrane attack complex(GO:0005579)
0.1 0.9 GO:0097413 Lewy body(GO:0097413)
0.1 0.7 GO:0033269 internode region of axon(GO:0033269)
0.1 0.8 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 0.8 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.1 0.8 GO:0005688 U6 snRNP(GO:0005688)
0.1 0.3 GO:1990923 PET complex(GO:1990923)
0.1 0.4 GO:0044530 supraspliceosomal complex(GO:0044530)
0.1 0.4 GO:0033061 DNA recombinase mediator complex(GO:0033061)
0.0 0.4 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.6 GO:0005675 holo TFIIH complex(GO:0005675)
0.0 0.7 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.3 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.7 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 1.3 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.5 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.2 GO:0036396 MIS complex(GO:0036396)
0.0 0.1 GO:0072534 perineuronal net(GO:0072534)
0.0 0.4 GO:0030686 90S preribosome(GO:0030686)
0.0 0.3 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.9 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.1 GO:0043159 acrosomal matrix(GO:0043159)
0.0 0.6 GO:0033655 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.0 1.0 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.2 GO:0032807 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807)
0.0 0.3 GO:0061574 ASAP complex(GO:0061574)
0.0 0.4 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.3 GO:0001520 outer dense fiber(GO:0001520)
0.0 0.9 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 1.1 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.6 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.2 GO:0005838 proteasome regulatory particle(GO:0005838)
0.0 0.3 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 0.1 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.5 GO:0043196 varicosity(GO:0043196)
0.0 0.6 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.2 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0 0.3 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.4 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.3 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.4 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.1 GO:0033263 CORVET complex(GO:0033263)
0.0 0.8 GO:0031430 M band(GO:0031430)
0.0 0.4 GO:1902562 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.2 GO:0044754 autolysosome(GO:0044754)
0.0 0.2 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.4 GO:0030673 axolemma(GO:0030673)
0.0 0.1 GO:0031415 NatA complex(GO:0031415)
0.0 0.5 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 1.0 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 1.2 GO:0005811 lipid particle(GO:0005811)
0.0 0.3 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.2 GO:0071564 npBAF complex(GO:0071564)
0.0 0.2 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.7 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0003960 NADPH:quinone reductase activity(GO:0003960) alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.5 1.5 GO:0036361 racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661)
0.4 2.6 GO:0008172 S-methyltransferase activity(GO:0008172)
0.3 0.8 GO:0004155 6,7-dihydropteridine reductase activity(GO:0004155)
0.3 3.8 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.2 0.7 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.2 0.5 GO:0098809 nitrite reductase activity(GO:0098809)
0.2 3.2 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.1 4.0 GO:0005550 pheromone binding(GO:0005550)
0.1 0.4 GO:0004816 asparagine-tRNA ligase activity(GO:0004816)
0.1 1.3 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 1.7 GO:0005347 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.1 0.8 GO:0042731 PH domain binding(GO:0042731)
0.1 2.5 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.1 1.2 GO:0001594 trace-amine receptor activity(GO:0001594)
0.1 0.6 GO:0000405 bubble DNA binding(GO:0000405)
0.1 0.7 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.1 0.5 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.1 0.7 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.1 0.3 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.1 0.3 GO:0047787 delta4-3-oxosteroid 5beta-reductase activity(GO:0047787)
0.1 1.0 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 0.3 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.1 0.2 GO:0036132 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.1 1.0 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.1 1.3 GO:0046527 glucosyltransferase activity(GO:0046527)
0.1 0.3 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.1 0.2 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.1 0.5 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.1 0.5 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.1 0.3 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.1 0.2 GO:1904047 S-adenosyl-L-methionine binding(GO:1904047)
0.1 0.4 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.1 1.1 GO:0019825 oxygen binding(GO:0019825)
0.1 0.8 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.1 0.2 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.1 0.4 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 0.8 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.3 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.0 0.9 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 1.1 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.4 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.7 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 1.1 GO:0005521 lamin binding(GO:0005521)
0.0 0.1 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.0 0.3 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.0 0.6 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.0 3.2 GO:0008170 N-methyltransferase activity(GO:0008170)
0.0 0.1 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.0 0.5 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.6 GO:0035174 histone serine kinase activity(GO:0035174)
0.0 0.9 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.4 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.0 0.2 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 0.3 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.5 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.5 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.6 GO:0005537 mannose binding(GO:0005537)
0.0 0.2 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.2 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.8 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.1 GO:0000402 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)
0.0 0.1 GO:0050429 calcium-dependent phospholipase C activity(GO:0050429)
0.0 0.1 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.4 GO:0016594 glycine binding(GO:0016594)
0.0 0.3 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.4 GO:0005542 folic acid binding(GO:0005542)
0.0 0.4 GO:0015238 drug transmembrane transporter activity(GO:0015238)
0.0 0.2 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 1.1 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.1 GO:0031493 nucleosomal histone binding(GO:0031493)
0.0 0.7 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.6 GO:1901505 carbohydrate derivative transporter activity(GO:1901505)
0.0 0.4 GO:0008198 ferrous iron binding(GO:0008198)
0.0 2.1 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.0 0.1 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.2 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.3 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.7 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.2 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.2 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.5 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 1.9 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.3 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.3 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.2 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.1 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.1 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.1 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.0 0.3 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.0 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.8 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.3 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.8 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.6 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 1.1 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.5 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 2.5 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 0.7 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 0.7 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.1 0.8 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 0.6 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1 1.6 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 1.0 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 1.7 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0 0.8 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.5 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.5 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.4 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 1.0 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.4 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.8 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 1.5 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.4 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.5 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.3 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.8 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.0 0.4 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 1.1 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.2 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.0 0.5 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 1.3 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.3 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.8 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.2 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.0 0.4 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.6 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.5 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.7 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.3 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.6 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters