avrg: GSE58827: Dynamics of the Mouse Liver
Gene Symbol | Gene ID | Gene Info |
---|---|---|
Ikzf2
|
ENSMUSG00000025997.7 | IKAROS family zinc finger 2 |
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Ikzf2 | mm10_v2_chr1_-_69685937_69685966 | 0.49 | 2.4e-03 | Click! |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.9 | 2.7 | GO:0002436 | immune complex clearance by monocytes and macrophages(GO:0002436) astrocyte chemotaxis(GO:0035700) regulation of immune complex clearance by monocytes and macrophages(GO:0090264) positive regulation of immune complex clearance by monocytes and macrophages(GO:0090265) negative regulation of eosinophil activation(GO:1902567) positive regulation of CD8-positive, alpha-beta T cell extravasation(GO:2000451) regulation of astrocyte chemotaxis(GO:2000458) |
0.6 | 1.9 | GO:0033082 | regulation of extrathymic T cell differentiation(GO:0033082) |
0.5 | 4.1 | GO:2000346 | negative regulation of hepatocyte proliferation(GO:2000346) |
0.4 | 1.1 | GO:0003345 | proepicardium cell migration involved in pericardium morphogenesis(GO:0003345) |
0.3 | 1.2 | GO:1903225 | negative regulation of endodermal cell differentiation(GO:1903225) |
0.3 | 0.8 | GO:0002632 | regulation of granuloma formation(GO:0002631) negative regulation of granuloma formation(GO:0002632) regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573) |
0.2 | 0.6 | GO:2000328 | regulation of T-helper 17 cell lineage commitment(GO:2000328) |
0.2 | 0.8 | GO:2000182 | regulation of progesterone biosynthetic process(GO:2000182) |
0.2 | 1.3 | GO:0033031 | positive regulation of neutrophil apoptotic process(GO:0033031) |
0.2 | 0.6 | GO:0007521 | muscle cell fate determination(GO:0007521) positive regulation of macrophage apoptotic process(GO:2000111) |
0.2 | 1.0 | GO:0036394 | amylase secretion(GO:0036394) |
0.1 | 0.7 | GO:1903566 | positive regulation of protein localization to cilium(GO:1903566) |
0.1 | 1.9 | GO:0060710 | chorio-allantoic fusion(GO:0060710) |
0.1 | 0.2 | GO:0035481 | Notch signaling pathway involved in heart induction(GO:0003137) regulation of Notch signaling pathway involved in heart induction(GO:0035480) positive regulation of Notch signaling pathway involved in heart induction(GO:0035481) |
0.1 | 1.1 | GO:0043353 | enucleate erythrocyte differentiation(GO:0043353) |
0.1 | 0.5 | GO:0015827 | aromatic amino acid transport(GO:0015801) tryptophan transport(GO:0015827) |
0.1 | 0.9 | GO:1904220 | regulation of serine C-palmitoyltransferase activity(GO:1904220) |
0.1 | 0.3 | GO:0045004 | DNA replication proofreading(GO:0045004) |
0.1 | 1.2 | GO:0097067 | cellular response to thyroid hormone stimulus(GO:0097067) |
0.1 | 1.5 | GO:0015809 | arginine transport(GO:0015809) |
0.1 | 3.3 | GO:0051482 | positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482) |
0.1 | 0.6 | GO:0035469 | determination of pancreatic left/right asymmetry(GO:0035469) |
0.1 | 0.7 | GO:0016584 | nucleosome positioning(GO:0016584) |
0.1 | 0.7 | GO:0015074 | DNA integration(GO:0015074) |
0.1 | 0.2 | GO:0072194 | kidney smooth muscle tissue development(GO:0072194) |
0.1 | 0.9 | GO:0000083 | regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083) |
0.1 | 0.6 | GO:2000766 | negative regulation of cytoplasmic translation(GO:2000766) |
0.1 | 1.0 | GO:0045779 | negative regulation of bone resorption(GO:0045779) |
0.1 | 0.2 | GO:0061357 | positive regulation of Wnt protein secretion(GO:0061357) |
0.0 | 0.3 | GO:0034080 | CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641) |
0.0 | 1.4 | GO:0060009 | Sertoli cell development(GO:0060009) |
0.0 | 0.1 | GO:0043396 | corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) positive regulation of corticotropin-releasing hormone secretion(GO:0051466) |
0.0 | 2.4 | GO:0061049 | physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049) |
0.0 | 0.1 | GO:0000821 | regulation of arginine metabolic process(GO:0000821) |
0.0 | 0.4 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
0.0 | 0.8 | GO:0003334 | keratinocyte development(GO:0003334) |
0.0 | 0.1 | GO:0021558 | oculomotor nerve development(GO:0021557) trochlear nerve development(GO:0021558) auditory receptor cell fate determination(GO:0042668) negative regulation of forebrain neuron differentiation(GO:2000978) |
0.0 | 1.1 | GO:0050869 | negative regulation of B cell activation(GO:0050869) |
0.0 | 0.4 | GO:0051574 | positive regulation of histone H3-K9 methylation(GO:0051574) |
0.0 | 0.3 | GO:0010908 | regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) |
0.0 | 1.1 | GO:0006376 | mRNA splice site selection(GO:0006376) |
0.0 | 0.2 | GO:0003199 | endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199) |
0.0 | 0.1 | GO:0010980 | regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980) |
0.0 | 0.1 | GO:1903378 | positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378) |
0.0 | 0.9 | GO:0045954 | positive regulation of natural killer cell mediated cytotoxicity(GO:0045954) |
0.0 | 0.3 | GO:0031507 | heterochromatin assembly(GO:0031507) |
0.0 | 0.1 | GO:0060008 | Sertoli cell differentiation(GO:0060008) |
0.0 | 0.9 | GO:0000381 | regulation of alternative mRNA splicing, via spliceosome(GO:0000381) |
0.0 | 0.4 | GO:0016973 | poly(A)+ mRNA export from nucleus(GO:0016973) |
0.0 | 0.5 | GO:0046855 | negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067) inositol phosphate dephosphorylation(GO:0046855) |
0.0 | 2.0 | GO:0035773 | insulin secretion involved in cellular response to glucose stimulus(GO:0035773) |
0.0 | 0.2 | GO:0039694 | viral RNA genome replication(GO:0039694) RNA replication(GO:0039703) |
0.0 | 0.4 | GO:0032012 | ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012) |
0.0 | 0.9 | GO:0051865 | protein autoubiquitination(GO:0051865) |
0.0 | 0.4 | GO:0045662 | negative regulation of myoblast differentiation(GO:0045662) |
0.0 | 0.6 | GO:0030195 | negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 1.2 | GO:0005588 | collagen type V trimer(GO:0005588) |
0.2 | 0.9 | GO:0008623 | CHRAC(GO:0008623) |
0.1 | 0.9 | GO:0097504 | Gemini of coiled bodies(GO:0097504) |
0.1 | 1.5 | GO:0005677 | chromatin silencing complex(GO:0005677) |
0.1 | 0.9 | GO:0005927 | muscle tendon junction(GO:0005927) |
0.1 | 0.9 | GO:0017059 | serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211) |
0.1 | 1.0 | GO:0032591 | dendritic spine membrane(GO:0032591) |
0.1 | 0.3 | GO:0071007 | U2-type catalytic step 2 spliceosome(GO:0071007) |
0.1 | 0.3 | GO:0008622 | epsilon DNA polymerase complex(GO:0008622) |
0.1 | 1.8 | GO:0032982 | myosin filament(GO:0032982) |
0.1 | 2.7 | GO:0002102 | podosome(GO:0002102) |
0.1 | 1.6 | GO:0005942 | phosphatidylinositol 3-kinase complex(GO:0005942) |
0.0 | 0.2 | GO:0002193 | MAML1-RBP-Jkappa- ICN1 complex(GO:0002193) |
0.0 | 0.1 | GO:0097059 | CRLF-CLCF1 complex(GO:0097058) CNTFR-CLCF1 complex(GO:0097059) |
0.0 | 0.1 | GO:1990452 | Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452) |
0.0 | 0.3 | GO:0070369 | beta-catenin-TCF7L2 complex(GO:0070369) |
0.0 | 0.5 | GO:0030014 | CCR4-NOT complex(GO:0030014) |
0.0 | 0.6 | GO:1990124 | messenger ribonucleoprotein complex(GO:1990124) |
0.0 | 1.1 | GO:0044295 | axonal growth cone(GO:0044295) |
0.0 | 0.8 | GO:0097440 | apical dendrite(GO:0097440) |
0.0 | 0.4 | GO:0000346 | transcription export complex(GO:0000346) |
0.0 | 2.2 | GO:0036126 | sperm flagellum(GO:0036126) |
0.0 | 0.1 | GO:0070847 | core mediator complex(GO:0070847) |
0.0 | 0.4 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
0.0 | 0.2 | GO:0090543 | Flemming body(GO:0090543) |
0.0 | 1.3 | GO:0005905 | clathrin-coated pit(GO:0005905) |
0.0 | 1.3 | GO:0001669 | acrosomal vesicle(GO:0001669) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.9 | 2.7 | GO:0035717 | chemokine (C-C motif) ligand 7 binding(GO:0035717) |
0.2 | 1.9 | GO:0008131 | primary amine oxidase activity(GO:0008131) |
0.2 | 1.5 | GO:0015181 | arginine transmembrane transporter activity(GO:0015181) |
0.2 | 0.9 | GO:0016454 | serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454) |
0.2 | 0.5 | GO:0016314 | phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314) |
0.1 | 1.3 | GO:0046934 | phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813) |
0.1 | 0.8 | GO:0070915 | lysophosphatidic acid receptor activity(GO:0070915) |
0.1 | 0.8 | GO:0061578 | Lys63-specific deubiquitinase activity(GO:0061578) |
0.1 | 0.5 | GO:0008241 | peptidyl-dipeptidase activity(GO:0008241) |
0.1 | 1.1 | GO:0045499 | chemorepellent activity(GO:0045499) |
0.1 | 1.0 | GO:0030346 | protein phosphatase 2B binding(GO:0030346) |
0.1 | 2.7 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
0.0 | 0.2 | GO:0035005 | 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005) |
0.0 | 0.3 | GO:0008310 | single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310) |
0.0 | 0.7 | GO:0043422 | protein kinase B binding(GO:0043422) |
0.0 | 0.6 | GO:0000900 | translation repressor activity, nucleic acid binding(GO:0000900) |
0.0 | 0.6 | GO:0003680 | AT DNA binding(GO:0003680) |
0.0 | 0.1 | GO:0071820 | N-box binding(GO:0071820) |
0.0 | 3.5 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
0.0 | 0.1 | GO:0050816 | phosphothreonine binding(GO:0050816) |
0.0 | 1.4 | GO:0036002 | pre-mRNA binding(GO:0036002) |
0.0 | 1.2 | GO:0070888 | bHLH transcription factor binding(GO:0043425) E-box binding(GO:0070888) |
0.0 | 1.0 | GO:0008536 | Ran GTPase binding(GO:0008536) |
0.0 | 0.1 | GO:0005105 | type 1 fibroblast growth factor receptor binding(GO:0005105) |
0.0 | 0.1 | GO:0015174 | basic amino acid transmembrane transporter activity(GO:0015174) |
0.0 | 0.1 | GO:0005127 | ciliary neurotrophic factor receptor binding(GO:0005127) |
0.0 | 0.4 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
0.0 | 1.2 | GO:0031491 | nucleosome binding(GO:0031491) |
0.0 | 0.6 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
0.0 | 1.2 | GO:0019894 | kinesin binding(GO:0019894) |
0.0 | 0.6 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
0.0 | 0.5 | GO:0001103 | RNA polymerase II repressing transcription factor binding(GO:0001103) |
0.0 | 0.2 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
0.0 | 0.4 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 5.7 | PID INTEGRIN A9B1 PATHWAY | Alpha9 beta1 integrin signaling events |
0.1 | 4.1 | PID ILK PATHWAY | Integrin-linked kinase signaling |
0.0 | 0.8 | PID LPA4 PATHWAY | LPA4-mediated signaling events |
0.0 | 1.3 | SA TRKA RECEPTOR | The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth. |
0.0 | 0.8 | PID HDAC CLASSIII PATHWAY | Signaling events mediated by HDAC Class III |
0.0 | 0.8 | PID NFKAPPAB CANONICAL PATHWAY | Canonical NF-kappaB pathway |
0.0 | 1.0 | NABA COLLAGENS | Genes encoding collagen proteins |
0.0 | 1.6 | PID SMAD2 3NUCLEAR PATHWAY | Regulation of nuclear SMAD2/3 signaling |
0.0 | 1.0 | PID NFAT 3PATHWAY | Role of Calcineurin-dependent NFAT signaling in lymphocytes |
0.0 | 1.9 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 2.7 | REACTOME BETA DEFENSINS | Genes involved in Beta defensins |
0.2 | 3.9 | REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
0.1 | 0.8 | REACTOME P2Y RECEPTORS | Genes involved in P2Y receptors |
0.0 | 1.9 | REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
0.0 | 0.7 | REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE | Genes involved in Synthesis of PIPs at the Golgi membrane |
0.0 | 0.9 | REACTOME DEADENYLATION OF MRNA | Genes involved in Deadenylation of mRNA |
0.0 | 1.0 | REACTOME REGULATION OF SIGNALING BY CBL | Genes involved in Regulation of signaling by CBL |
0.0 | 1.0 | REACTOME TRAFFICKING OF AMPA RECEPTORS | Genes involved in Trafficking of AMPA receptors |
0.0 | 1.4 | REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
0.0 | 0.8 | REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA | Genes involved in Circadian Repression of Expression by REV-ERBA |
0.0 | 1.2 | REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS | Genes involved in Regulation of Water Balance by Renal Aquaporins |
0.0 | 3.8 | REACTOME SIGNALING BY EGFR IN CANCER | Genes involved in Signaling by EGFR in Cancer |
0.0 | 0.3 | REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER | Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER |
0.0 | 0.8 | REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING | Genes involved in Negative regulators of RIG-I/MDA5 signaling |
0.0 | 0.6 | REACTOME ERK MAPK TARGETS | Genes involved in ERK/MAPK targets |
0.0 | 0.9 | REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
0.0 | 1.0 | REACTOME NCAM1 INTERACTIONS | Genes involved in NCAM1 interactions |
0.0 | 0.2 | REACTOME NOTCH HLH TRANSCRIPTION PATHWAY | Genes involved in Notch-HLH transcription pathway |
0.0 | 0.1 | REACTOME VEGF LIGAND RECEPTOR INTERACTIONS | Genes involved in VEGF ligand-receptor interactions |