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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Tbx3

Z-value: 0.56

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Transcription factors associated with Tbx3

Gene Symbol Gene ID Gene Info
ENSMUSG00000018604.12 T-box 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Tbx3mm10_v2_chr5_+_119670825_1196708620.231.7e-01Click!

Activity profile of Tbx3 motif

Sorted Z-values of Tbx3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Tbx3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.0 GO:0001980 regulation of systemic arterial blood pressure by ischemic conditions(GO:0001980)
0.2 0.6 GO:0006742 NADP catabolic process(GO:0006742)
0.1 1.0 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.1 0.3 GO:0046271 coumarin metabolic process(GO:0009804) phenylpropanoid catabolic process(GO:0046271)
0.1 0.5 GO:2000354 regulation of ovarian follicle development(GO:2000354)
0.0 0.3 GO:0060468 prevention of polyspermy(GO:0060468)
0.0 0.6 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.1 GO:0051977 lysophospholipid transport(GO:0051977)
0.0 0.3 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.2 GO:0019482 beta-alanine metabolic process(GO:0019482)
0.0 0.8 GO:0050907 detection of chemical stimulus involved in sensory perception(GO:0050907)
0.0 0.2 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 1.0 GO:0030239 myofibril assembly(GO:0030239)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.0 GO:1990584 cardiac Troponin complex(GO:1990584)
0.1 0.5 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 1.2 GO:0031430 M band(GO:0031430)
0.0 0.3 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.0 GO:0030172 troponin C binding(GO:0030172)
0.2 1.0 GO:0051373 FATZ binding(GO:0051373)
0.1 0.3 GO:0032190 acrosin binding(GO:0032190)
0.1 0.6 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 0.6 GO:0043855 cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.3 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 1.0 GO:0019213 deacetylase activity(GO:0019213)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.5 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 2.0 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction