avrg: GSE58827: Dynamics of the Mouse Liver
Gene Symbol | Gene ID | Gene Info |
---|---|---|
Tfap2c
|
ENSMUSG00000028640.5 | transcription factor AP-2, gamma |
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Tfap2c | mm10_v2_chr2_+_172550761_172550782 | 0.58 | 2.4e-04 | Click! |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
3.0 | 9.1 | GO:0002017 | regulation of blood volume by renal aldosterone(GO:0002017) |
1.7 | 10.4 | GO:0036515 | serotonergic neuron axon guidance(GO:0036515) |
1.7 | 6.8 | GO:0021941 | negative regulation of cerebellar granule cell precursor proliferation(GO:0021941) |
1.6 | 6.3 | GO:0086046 | membrane depolarization during SA node cell action potential(GO:0086046) |
1.6 | 6.2 | GO:2001245 | regulation of phosphatidylcholine biosynthetic process(GO:2001245) |
1.4 | 2.8 | GO:0071733 | transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579) |
1.2 | 3.7 | GO:0002270 | plasmacytoid dendritic cell activation(GO:0002270) |
1.2 | 6.2 | GO:0030951 | establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951) |
1.1 | 8.0 | GO:0060372 | regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372) |
1.1 | 3.4 | GO:0097309 | cap1 mRNA methylation(GO:0097309) |
1.1 | 5.5 | GO:0021993 | initiation of neural tube closure(GO:0021993) |
1.1 | 5.4 | GO:0010725 | regulation of primitive erythrocyte differentiation(GO:0010725) |
1.1 | 4.2 | GO:0030309 | poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311) |
1.0 | 5.9 | GO:0042699 | follicle-stimulating hormone signaling pathway(GO:0042699) |
1.0 | 14.5 | GO:0010216 | maintenance of DNA methylation(GO:0010216) |
0.9 | 3.8 | GO:0060032 | notochord regression(GO:0060032) |
0.8 | 3.2 | GO:0035519 | protein K29-linked ubiquitination(GO:0035519) |
0.8 | 2.4 | GO:2000312 | regulation of kainate selective glutamate receptor activity(GO:2000312) |
0.7 | 2.9 | GO:0097477 | neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812) lateral motor column neuron migration(GO:0097477) |
0.7 | 2.9 | GO:0010360 | negative regulation of anion channel activity(GO:0010360) |
0.7 | 1.3 | GO:0051466 | corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) positive regulation of corticotropin-releasing hormone secretion(GO:0051466) |
0.6 | 5.6 | GO:0010587 | miRNA catabolic process(GO:0010587) |
0.6 | 4.2 | GO:0016185 | synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185) |
0.6 | 2.3 | GO:0043973 | histone H3-K4 acetylation(GO:0043973) |
0.6 | 4.7 | GO:0070245 | positive regulation of thymocyte apoptotic process(GO:0070245) |
0.6 | 9.9 | GO:0030953 | astral microtubule organization(GO:0030953) |
0.6 | 2.8 | GO:0035992 | tendon cell differentiation(GO:0035990) tendon formation(GO:0035992) |
0.5 | 3.7 | GO:2000672 | negative regulation of motor neuron apoptotic process(GO:2000672) |
0.5 | 15.3 | GO:0046852 | positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852) |
0.5 | 6.2 | GO:0097067 | cellular response to thyroid hormone stimulus(GO:0097067) |
0.5 | 3.6 | GO:0061087 | positive regulation of histone H3-K27 methylation(GO:0061087) |
0.5 | 7.7 | GO:0043249 | erythrocyte maturation(GO:0043249) |
0.5 | 1.5 | GO:0006589 | octopamine biosynthetic process(GO:0006589) octopamine metabolic process(GO:0046333) |
0.5 | 0.5 | GO:0033122 | negative regulation of purine nucleotide catabolic process(GO:0033122) |
0.5 | 2.5 | GO:0070459 | acetylcholine secretion, neurotransmission(GO:0014055) regulation of acetylcholine secretion, neurotransmission(GO:0014056) operant conditioning(GO:0035106) prolactin secretion(GO:0070459) |
0.5 | 2.8 | GO:0015819 | lysine transport(GO:0015819) ornithine transport(GO:0015822) |
0.4 | 6.5 | GO:0043589 | skin morphogenesis(GO:0043589) |
0.4 | 1.6 | GO:0035522 | monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522) |
0.4 | 6.1 | GO:0006968 | cellular defense response(GO:0006968) |
0.4 | 1.6 | GO:1901376 | mycotoxin metabolic process(GO:0043385) aflatoxin metabolic process(GO:0046222) organic heteropentacyclic compound metabolic process(GO:1901376) |
0.4 | 3.9 | GO:0030206 | chondroitin sulfate biosynthetic process(GO:0030206) |
0.4 | 5.4 | GO:0042090 | interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075) |
0.4 | 3.8 | GO:0070236 | negative regulation of activation-induced cell death of T cells(GO:0070236) |
0.4 | 1.5 | GO:0097350 | neutrophil clearance(GO:0097350) |
0.4 | 1.8 | GO:1905247 | positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) negative regulation of metalloendopeptidase activity(GO:1904684) positive regulation of aspartic-type peptidase activity(GO:1905247) |
0.3 | 2.3 | GO:0035331 | negative regulation of hippo signaling(GO:0035331) protein localization to adherens junction(GO:0071896) |
0.3 | 3.3 | GO:1902036 | regulation of hematopoietic stem cell differentiation(GO:1902036) |
0.3 | 1.2 | GO:0098887 | neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) |
0.3 | 2.6 | GO:0010606 | positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606) |
0.3 | 2.0 | GO:0016584 | nucleosome positioning(GO:0016584) |
0.3 | 2.3 | GO:0099550 | trans-synaptic signalling, modulating synaptic transmission(GO:0099550) |
0.3 | 1.1 | GO:0045578 | negative regulation of B cell differentiation(GO:0045578) |
0.3 | 12.1 | GO:0006779 | porphyrin-containing compound biosynthetic process(GO:0006779) |
0.3 | 1.3 | GO:0007195 | adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195) |
0.2 | 1.2 | GO:0035617 | stress granule disassembly(GO:0035617) |
0.2 | 6.2 | GO:0007263 | nitric oxide mediated signal transduction(GO:0007263) |
0.2 | 1.2 | GO:0097527 | necroptotic signaling pathway(GO:0097527) |
0.2 | 3.1 | GO:0014807 | regulation of somitogenesis(GO:0014807) |
0.2 | 3.1 | GO:0061469 | regulation of type B pancreatic cell proliferation(GO:0061469) |
0.2 | 3.3 | GO:0097119 | postsynaptic density protein 95 clustering(GO:0097119) |
0.2 | 0.7 | GO:0002309 | T cell proliferation involved in immune response(GO:0002309) |
0.2 | 1.8 | GO:0014029 | neural crest formation(GO:0014029) |
0.2 | 0.9 | GO:1901842 | negative regulation of high voltage-gated calcium channel activity(GO:1901842) |
0.2 | 1.1 | GO:2000622 | regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623) |
0.2 | 1.7 | GO:0071557 | histone H3-K27 demethylation(GO:0071557) |
0.2 | 1.4 | GO:0016480 | negative regulation of transcription from RNA polymerase III promoter(GO:0016480) |
0.2 | 0.6 | GO:0071879 | positive regulation of adrenergic receptor signaling pathway(GO:0071879) |
0.2 | 0.9 | GO:0090038 | negative regulation of protein kinase C signaling(GO:0090038) |
0.2 | 1.9 | GO:0098903 | regulation of membrane repolarization during action potential(GO:0098903) |
0.2 | 1.3 | GO:0090074 | negative regulation of protein homodimerization activity(GO:0090074) |
0.2 | 2.5 | GO:0060033 | anatomical structure regression(GO:0060033) |
0.2 | 0.5 | GO:1903406 | regulation of sodium:potassium-exchanging ATPase activity(GO:1903406) |
0.2 | 1.0 | GO:0003431 | growth plate cartilage chondrocyte development(GO:0003431) |
0.2 | 1.5 | GO:0006020 | inositol metabolic process(GO:0006020) |
0.2 | 0.9 | GO:0015015 | heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015) |
0.1 | 0.4 | GO:1904742 | regulation of telomeric DNA binding(GO:1904742) |
0.1 | 2.9 | GO:0001675 | acrosome assembly(GO:0001675) |
0.1 | 0.6 | GO:0097118 | neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118) |
0.1 | 2.2 | GO:0030853 | negative regulation of granulocyte differentiation(GO:0030853) |
0.1 | 1.2 | GO:0032264 | IMP salvage(GO:0032264) |
0.1 | 4.5 | GO:0031069 | hair follicle morphogenesis(GO:0031069) |
0.1 | 1.9 | GO:0031915 | positive regulation of synaptic plasticity(GO:0031915) |
0.1 | 4.5 | GO:0000154 | rRNA modification(GO:0000154) |
0.1 | 0.7 | GO:0015760 | hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760) |
0.1 | 0.6 | GO:0060158 | phospholipase C-activating dopamine receptor signaling pathway(GO:0060158) |
0.1 | 0.8 | GO:0042421 | norepinephrine biosynthetic process(GO:0042421) |
0.1 | 4.7 | GO:0090162 | establishment of epithelial cell polarity(GO:0090162) |
0.1 | 0.4 | GO:0055099 | response to high density lipoprotein particle(GO:0055099) |
0.1 | 0.5 | GO:1902167 | positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902167) |
0.1 | 1.5 | GO:0060510 | Type II pneumocyte differentiation(GO:0060510) |
0.1 | 2.2 | GO:2000052 | positive regulation of non-canonical Wnt signaling pathway(GO:2000052) |
0.1 | 0.4 | GO:0035405 | histone-threonine phosphorylation(GO:0035405) |
0.1 | 2.1 | GO:0046185 | aldehyde catabolic process(GO:0046185) |
0.1 | 11.2 | GO:0030168 | platelet activation(GO:0030168) |
0.1 | 1.4 | GO:0021957 | corticospinal tract morphogenesis(GO:0021957) |
0.1 | 4.9 | GO:0061515 | myeloid cell development(GO:0061515) |
0.1 | 0.4 | GO:1902951 | negative regulation of dendritic spine maintenance(GO:1902951) |
0.1 | 0.6 | GO:0000056 | ribosomal small subunit export from nucleus(GO:0000056) |
0.1 | 1.0 | GO:2000310 | regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310) |
0.1 | 1.4 | GO:0021670 | lateral ventricle development(GO:0021670) |
0.1 | 0.2 | GO:0072382 | minus-end-directed vesicle transport along microtubule(GO:0072382) regulation of metaphase plate congression(GO:0090235) |
0.1 | 0.3 | GO:0036324 | vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324) |
0.1 | 1.3 | GO:0043968 | histone H2A acetylation(GO:0043968) |
0.1 | 0.6 | GO:0035269 | protein O-linked mannosylation(GO:0035269) |
0.1 | 0.5 | GO:0007000 | nucleolus organization(GO:0007000) |
0.1 | 0.2 | GO:0007308 | oocyte construction(GO:0007308) oocyte axis specification(GO:0007309) oocyte anterior/posterior axis specification(GO:0007314) pole plasm assembly(GO:0007315) maternal determination of anterior/posterior axis, embryo(GO:0008358) P granule organization(GO:0030719) |
0.1 | 0.8 | GO:0098703 | calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035) |
0.1 | 5.0 | GO:0090263 | positive regulation of canonical Wnt signaling pathway(GO:0090263) |
0.1 | 2.2 | GO:0045197 | establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197) |
0.1 | 2.2 | GO:0000027 | ribosomal large subunit assembly(GO:0000027) |
0.1 | 1.8 | GO:0048025 | negative regulation of mRNA splicing, via spliceosome(GO:0048025) |
0.0 | 1.7 | GO:0030513 | positive regulation of BMP signaling pathway(GO:0030513) |
0.0 | 0.5 | GO:0035873 | lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879) |
0.0 | 0.9 | GO:0034587 | piRNA metabolic process(GO:0034587) |
0.0 | 0.3 | GO:2000270 | negative regulation of fibroblast apoptotic process(GO:2000270) |
0.0 | 0.3 | GO:0021615 | glossopharyngeal nerve morphogenesis(GO:0021615) |
0.0 | 0.8 | GO:0035428 | hexose transmembrane transport(GO:0035428) |
0.0 | 2.3 | GO:0030514 | negative regulation of BMP signaling pathway(GO:0030514) |
0.0 | 0.4 | GO:0032331 | negative regulation of chondrocyte differentiation(GO:0032331) |
0.0 | 4.7 | GO:0046546 | male gonad development(GO:0008584) development of primary male sexual characteristics(GO:0046546) |
0.0 | 0.2 | GO:0098532 | histone H3-K27 trimethylation(GO:0098532) |
0.0 | 0.9 | GO:0060325 | face morphogenesis(GO:0060325) |
0.0 | 2.0 | GO:0048286 | lung alveolus development(GO:0048286) |
0.0 | 1.1 | GO:0043550 | regulation of lipid kinase activity(GO:0043550) |
0.0 | 0.2 | GO:0046015 | regulation of transcription by glucose(GO:0046015) |
0.0 | 2.3 | GO:0008306 | associative learning(GO:0008306) |
0.0 | 1.7 | GO:0030509 | BMP signaling pathway(GO:0030509) |
0.0 | 0.3 | GO:0021796 | cerebral cortex regionalization(GO:0021796) |
0.0 | 0.4 | GO:0071260 | cellular response to mechanical stimulus(GO:0071260) |
0.0 | 0.9 | GO:0051568 | histone H3-K4 methylation(GO:0051568) |
0.0 | 1.8 | GO:0007173 | epidermal growth factor receptor signaling pathway(GO:0007173) |
0.0 | 0.6 | GO:0006904 | vesicle docking involved in exocytosis(GO:0006904) |
0.0 | 0.3 | GO:0000289 | nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289) |
0.0 | 2.4 | GO:0065004 | protein-DNA complex assembly(GO:0065004) |
0.0 | 0.2 | GO:0016339 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339) |
0.0 | 0.1 | GO:0031053 | primary miRNA processing(GO:0031053) |
0.0 | 1.0 | GO:0051453 | regulation of intracellular pH(GO:0051453) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.1 | 6.4 | GO:0005584 | collagen type I trimer(GO:0005584) |
1.7 | 12.1 | GO:0008091 | spectrin(GO:0008091) |
1.6 | 6.4 | GO:0060187 | cell pole(GO:0060187) |
0.9 | 3.7 | GO:0097058 | CRLF-CLCF1 complex(GO:0097058) |
0.9 | 6.2 | GO:0005638 | lamin filament(GO:0005638) |
0.9 | 2.6 | GO:0031251 | PAN complex(GO:0031251) |
0.7 | 5.2 | GO:0061689 | tricellular tight junction(GO:0061689) |
0.6 | 4.5 | GO:0031428 | box C/D snoRNP complex(GO:0031428) |
0.6 | 1.8 | GO:0070381 | endosome to plasma membrane transport vesicle(GO:0070381) |
0.5 | 1.8 | GO:0070033 | synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) |
0.4 | 8.9 | GO:0031091 | platelet alpha granule(GO:0031091) |
0.3 | 5.9 | GO:0031143 | pseudopodium(GO:0031143) |
0.3 | 17.8 | GO:0000791 | euchromatin(GO:0000791) |
0.3 | 3.8 | GO:0097542 | ciliary tip(GO:0097542) |
0.3 | 1.3 | GO:0032777 | Piccolo NuA4 histone acetyltransferase complex(GO:0032777) |
0.2 | 2.2 | GO:0097427 | microtubule bundle(GO:0097427) |
0.2 | 3.9 | GO:0032580 | Golgi cisterna membrane(GO:0032580) |
0.2 | 1.9 | GO:1990454 | L-type voltage-gated calcium channel complex(GO:1990454) |
0.2 | 22.3 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
0.2 | 3.9 | GO:0032433 | filopodium tip(GO:0032433) |
0.2 | 4.2 | GO:0043196 | varicosity(GO:0043196) |
0.2 | 3.6 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
0.2 | 6.5 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
0.1 | 0.9 | GO:0071547 | piP-body(GO:0071547) |
0.1 | 2.3 | GO:0031932 | TORC2 complex(GO:0031932) |
0.1 | 3.2 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
0.1 | 5.7 | GO:0031519 | PcG protein complex(GO:0031519) |
0.1 | 0.6 | GO:0070820 | cytolytic granule(GO:0044194) tertiary granule(GO:0070820) |
0.1 | 2.8 | GO:0097038 | perinuclear endoplasmic reticulum(GO:0097038) |
0.1 | 1.0 | GO:0005583 | fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643) |
0.1 | 1.2 | GO:0048188 | Set1C/COMPASS complex(GO:0048188) |
0.1 | 2.4 | GO:0098839 | postsynaptic density membrane(GO:0098839) |
0.1 | 6.0 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
0.1 | 4.0 | GO:0043034 | costamere(GO:0043034) |
0.1 | 6.2 | GO:0016529 | sarcoplasmic reticulum(GO:0016529) |
0.1 | 0.3 | GO:1990032 | parallel fiber(GO:1990032) |
0.1 | 7.8 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
0.1 | 1.5 | GO:0033643 | host(GO:0018995) host cell part(GO:0033643) host cell(GO:0043657) |
0.1 | 1.2 | GO:0035253 | ciliary rootlet(GO:0035253) |
0.1 | 1.5 | GO:0071339 | MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339) |
0.1 | 0.2 | GO:0033553 | rDNA heterochromatin(GO:0033553) |
0.1 | 2.0 | GO:0000788 | nuclear nucleosome(GO:0000788) |
0.0 | 1.3 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
0.0 | 1.9 | GO:0016592 | mediator complex(GO:0016592) |
0.0 | 1.0 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
0.0 | 14.3 | GO:0014069 | postsynaptic density(GO:0014069) |
0.0 | 14.4 | GO:0000790 | nuclear chromatin(GO:0000790) |
0.0 | 2.1 | GO:0005876 | spindle microtubule(GO:0005876) |
0.0 | 15.1 | GO:0009897 | external side of plasma membrane(GO:0009897) |
0.0 | 0.5 | GO:0005736 | DNA-directed RNA polymerase I complex(GO:0005736) |
0.0 | 0.4 | GO:0097431 | mitotic spindle pole(GO:0097431) |
0.0 | 2.6 | GO:0005811 | lipid particle(GO:0005811) |
0.0 | 0.2 | GO:0002177 | manchette(GO:0002177) |
0.0 | 0.4 | GO:0032809 | neuronal cell body membrane(GO:0032809) |
0.0 | 2.4 | GO:0032993 | protein-DNA complex(GO:0032993) |
0.0 | 2.1 | GO:0043197 | dendritic spine(GO:0043197) |
0.0 | 0.5 | GO:0001891 | phagocytic cup(GO:0001891) |
0.0 | 0.6 | GO:0045095 | keratin filament(GO:0045095) |
0.0 | 0.5 | GO:0005771 | multivesicular body(GO:0005771) |
0.0 | 9.4 | GO:0005813 | centrosome(GO:0005813) |
0.0 | 0.8 | GO:0016235 | aggresome(GO:0016235) |
0.0 | 0.4 | GO:0031307 | integral component of mitochondrial outer membrane(GO:0031307) |
0.0 | 0.8 | GO:0030119 | AP-type membrane coat adaptor complex(GO:0030119) |
0.0 | 0.8 | GO:0005905 | clathrin-coated pit(GO:0005905) |
0.0 | 0.7 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
0.0 | 4.8 | GO:0005667 | transcription factor complex(GO:0005667) |
0.0 | 0.9 | GO:0030864 | cortical actin cytoskeleton(GO:0030864) |
0.0 | 0.4 | GO:0097610 | cell division site(GO:0032153) cleavage furrow(GO:0032154) cell division site part(GO:0032155) cell surface furrow(GO:0097610) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
3.0 | 9.1 | GO:0003845 | 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845) |
2.4 | 14.5 | GO:0031493 | nucleosomal histone binding(GO:0031493) |
2.3 | 6.8 | GO:0005330 | dopamine:sodium symporter activity(GO:0005330) |
2.1 | 6.2 | GO:0047192 | 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192) |
2.0 | 5.9 | GO:0031896 | V2 vasopressin receptor binding(GO:0031896) |
1.6 | 6.3 | GO:0008332 | low voltage-gated calcium channel activity(GO:0008332) |
1.4 | 4.2 | GO:0016262 | protein N-acetylglucosaminyltransferase activity(GO:0016262) |
1.3 | 3.9 | GO:0050510 | N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510) |
1.2 | 3.7 | GO:0000401 | open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402) |
0.9 | 1.7 | GO:0071558 | histone demethylase activity (H3-K27 specific)(GO:0071558) |
0.9 | 3.4 | GO:0004483 | mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483) |
0.8 | 2.5 | GO:0004995 | tachykinin receptor activity(GO:0004995) |
0.8 | 8.0 | GO:0086008 | voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008) |
0.7 | 2.9 | GO:0004703 | G-protein coupled receptor kinase activity(GO:0004703) |
0.7 | 3.3 | GO:1990188 | euchromatin binding(GO:1990188) |
0.6 | 1.8 | GO:0001042 | RNA polymerase I core binding(GO:0001042) |
0.6 | 2.8 | GO:0015189 | L-ornithine transmembrane transporter activity(GO:0000064) L-lysine transmembrane transporter activity(GO:0015189) |
0.5 | 1.5 | GO:0004500 | dopamine beta-monooxygenase activity(GO:0004500) |
0.5 | 3.7 | GO:0005127 | ciliary neurotrophic factor receptor binding(GO:0005127) |
0.4 | 1.8 | GO:0036313 | phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313) |
0.4 | 4.7 | GO:0031749 | D2 dopamine receptor binding(GO:0031749) |
0.4 | 6.4 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
0.4 | 2.1 | GO:0034648 | histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648) |
0.3 | 1.5 | GO:0000828 | inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724) |
0.3 | 2.1 | GO:0004030 | aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030) |
0.3 | 2.3 | GO:0070180 | large ribosomal subunit rRNA binding(GO:0070180) |
0.3 | 5.5 | GO:0051864 | histone demethylase activity (H3-K36 specific)(GO:0051864) |
0.3 | 2.0 | GO:0032564 | dATP binding(GO:0032564) |
0.3 | 7.1 | GO:0019956 | chemokine binding(GO:0019956) |
0.3 | 4.5 | GO:1990226 | histone methyltransferase binding(GO:1990226) |
0.3 | 1.4 | GO:0001032 | RNA polymerase III type 3 promoter DNA binding(GO:0001032) |
0.3 | 5.0 | GO:0050321 | tau-protein kinase activity(GO:0050321) |
0.2 | 0.7 | GO:0050309 | glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309) |
0.2 | 1.2 | GO:0045322 | unmethylated CpG binding(GO:0045322) |
0.2 | 6.0 | GO:0008266 | poly(U) RNA binding(GO:0008266) |
0.2 | 2.3 | GO:0008046 | axon guidance receptor activity(GO:0008046) |
0.2 | 0.9 | GO:0017095 | heparan sulfate 6-O-sulfotransferase activity(GO:0017095) |
0.2 | 1.3 | GO:0008294 | calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294) |
0.2 | 0.8 | GO:0004566 | beta-glucuronidase activity(GO:0004566) |
0.2 | 0.6 | GO:0031826 | type 2A serotonin receptor binding(GO:0031826) |
0.2 | 2.3 | GO:0030274 | LIM domain binding(GO:0030274) |
0.2 | 0.6 | GO:0070016 | armadillo repeat domain binding(GO:0070016) |
0.2 | 1.8 | GO:0098748 | clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
0.2 | 6.2 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
0.2 | 3.9 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
0.2 | 2.9 | GO:0043495 | protein anchor(GO:0043495) |
0.2 | 9.0 | GO:0070888 | E-box binding(GO:0070888) |
0.2 | 6.2 | GO:0030506 | ankyrin binding(GO:0030506) |
0.2 | 0.6 | GO:0030348 | syntaxin-3 binding(GO:0030348) |
0.2 | 3.4 | GO:0070742 | C2H2 zinc finger domain binding(GO:0070742) |
0.1 | 0.4 | GO:0034437 | glycoprotein transporter activity(GO:0034437) |
0.1 | 2.6 | GO:0004535 | poly(A)-specific ribonuclease activity(GO:0004535) |
0.1 | 1.2 | GO:0003876 | AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623) |
0.1 | 0.4 | GO:0035402 | histone kinase activity (H3-T11 specific)(GO:0035402) |
0.1 | 4.7 | GO:0051059 | NF-kappaB binding(GO:0051059) |
0.1 | 12.1 | GO:0033613 | activating transcription factor binding(GO:0033613) |
0.1 | 1.9 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
0.1 | 5.3 | GO:0035064 | methylated histone binding(GO:0035064) |
0.1 | 5.2 | GO:0043548 | phosphatidylinositol 3-kinase binding(GO:0043548) |
0.1 | 2.3 | GO:0005520 | insulin-like growth factor binding(GO:0005520) |
0.1 | 0.6 | GO:0070699 | type II activin receptor binding(GO:0070699) |
0.1 | 0.8 | GO:0005432 | calcium:sodium antiporter activity(GO:0005432) |
0.1 | 1.8 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
0.1 | 3.5 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
0.1 | 3.6 | GO:0005158 | insulin receptor binding(GO:0005158) |
0.1 | 0.2 | GO:0061628 | H3K27me3 modified histone binding(GO:0061628) |
0.1 | 0.5 | GO:0015129 | lactate transmembrane transporter activity(GO:0015129) |
0.1 | 1.2 | GO:0005123 | death receptor binding(GO:0005123) |
0.1 | 0.5 | GO:0000293 | ferric-chelate reductase activity(GO:0000293) cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851) |
0.1 | 0.6 | GO:1990825 | sequence-specific mRNA binding(GO:1990825) |
0.1 | 3.6 | GO:0097110 | scaffold protein binding(GO:0097110) |
0.1 | 1.3 | GO:0070628 | proteasome binding(GO:0070628) |
0.1 | 1.0 | GO:0008510 | sodium:bicarbonate symporter activity(GO:0008510) |
0.0 | 0.5 | GO:0031545 | peptidyl-proline 4-dioxygenase activity(GO:0031545) |
0.0 | 1.6 | GO:0008392 | arachidonic acid epoxygenase activity(GO:0008392) |
0.0 | 0.9 | GO:0070182 | DNA polymerase binding(GO:0070182) |
0.0 | 4.3 | GO:0008013 | beta-catenin binding(GO:0008013) |
0.0 | 0.4 | GO:0022833 | mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833) |
0.0 | 0.1 | GO:0070878 | primary miRNA binding(GO:0070878) |
0.0 | 9.4 | GO:0003714 | transcription corepressor activity(GO:0003714) |
0.0 | 2.2 | GO:0030507 | spectrin binding(GO:0030507) |
0.0 | 1.1 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
0.0 | 3.1 | GO:0046332 | SMAD binding(GO:0046332) |
0.0 | 1.8 | GO:0001205 | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205) |
0.0 | 3.2 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
0.0 | 0.5 | GO:0001054 | RNA polymerase I activity(GO:0001054) |
0.0 | 7.3 | GO:0019902 | phosphatase binding(GO:0019902) |
0.0 | 0.8 | GO:0005351 | sugar:proton symporter activity(GO:0005351) |
0.0 | 1.3 | GO:0004402 | histone acetyltransferase activity(GO:0004402) |
0.0 | 1.0 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
0.0 | 8.2 | GO:0005096 | GTPase activator activity(GO:0005096) |
0.0 | 1.6 | GO:0001158 | enhancer sequence-specific DNA binding(GO:0001158) |
0.0 | 1.7 | GO:0004843 | thiol-dependent ubiquitin-specific protease activity(GO:0004843) |
0.0 | 1.0 | GO:0030971 | receptor tyrosine kinase binding(GO:0030971) |
0.0 | 0.4 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
0.0 | 1.9 | GO:0005057 | receptor signaling protein activity(GO:0005057) |
0.0 | 0.6 | GO:0071855 | neuropeptide receptor binding(GO:0071855) |
0.0 | 0.3 | GO:0003756 | protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864) |
0.0 | 10.9 | GO:0000976 | transcription regulatory region sequence-specific DNA binding(GO:0000976) |
0.0 | 3.6 | GO:0030246 | carbohydrate binding(GO:0030246) |
0.0 | 3.1 | GO:0061630 | ubiquitin protein ligase activity(GO:0061630) |
0.0 | 0.9 | GO:0004004 | RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 11.0 | PID AURORA A PATHWAY | Aurora A signaling |
0.2 | 15.3 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
0.2 | 8.2 | PID IL8 CXCR1 PATHWAY | IL8- and CXCR1-mediated signaling events |
0.2 | 8.4 | ST B CELL ANTIGEN RECEPTOR | B Cell Antigen Receptor |
0.2 | 6.4 | PID LYMPH ANGIOGENESIS PATHWAY | VEGFR3 signaling in lymphatic endothelium |
0.1 | 0.6 | ST PAC1 RECEPTOR PATHWAY | PAC1 Receptor Pathway |
0.1 | 6.1 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
0.1 | 2.9 | ST TUMOR NECROSIS FACTOR PATHWAY | Tumor Necrosis Factor Pathway. |
0.1 | 4.2 | PID AMB2 NEUTROPHILS PATHWAY | amb2 Integrin signaling |
0.1 | 3.2 | PID LIS1 PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
0.1 | 5.7 | PID SMAD2 3NUCLEAR PATHWAY | Regulation of nuclear SMAD2/3 signaling |
0.1 | 0.6 | PID BETA CATENIN DEG PATHWAY | Degradation of beta catenin |
0.1 | 4.2 | PID HEDGEHOG GLI PATHWAY | Hedgehog signaling events mediated by Gli proteins |
0.1 | 3.4 | PID HDAC CLASSII PATHWAY | Signaling events mediated by HDAC Class II |
0.1 | 8.2 | PID BETA CATENIN NUC PATHWAY | Regulation of nuclear beta catenin signaling and target gene transcription |
0.1 | 3.6 | PID PTP1B PATHWAY | Signaling events mediated by PTP1B |
0.1 | 1.3 | PID LPA4 PATHWAY | LPA4-mediated signaling events |
0.1 | 2.0 | PID HDAC CLASSIII PATHWAY | Signaling events mediated by HDAC Class III |
0.1 | 6.8 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
0.1 | 3.5 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
0.1 | 1.3 | PID IL3 PATHWAY | IL3-mediated signaling events |
0.1 | 2.3 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
0.0 | 3.0 | WNT SIGNALING | Genes related to Wnt-mediated signal transduction |
0.0 | 3.4 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
0.0 | 1.2 | PID THROMBIN PAR1 PATHWAY | PAR1-mediated thrombin signaling events |
0.0 | 0.7 | PID IL2 PI3K PATHWAY | IL2 signaling events mediated by PI3K |
0.0 | 1.8 | NABA COLLAGENS | Genes encoding collagen proteins |
0.0 | 0.5 | PID HIF1A PATHWAY | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha |
0.0 | 1.1 | PID TELOMERASE PATHWAY | Regulation of Telomerase |
0.0 | 0.8 | PID ILK PATHWAY | Integrin-linked kinase signaling |
0.0 | 0.9 | ST FAS SIGNALING PATHWAY | Fas Signaling Pathway |
0.0 | 0.9 | PID LKB1 PATHWAY | LKB1 signaling events |
0.0 | 1.0 | PID RAC1 REG PATHWAY | Regulation of RAC1 activity |
0.0 | 0.3 | PID RAS PATHWAY | Regulation of Ras family activation |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.6 | 21.2 | REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS | Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus |
0.5 | 6.8 | REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN | Genes involved in Platelet Adhesion to exposed collagen |
0.3 | 6.2 | REACTOME ACYL CHAIN REMODELLING OF PG | Genes involved in Acyl chain remodelling of PG |
0.3 | 4.7 | REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION | Genes involved in Apoptosis induced DNA fragmentation |
0.3 | 11.5 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
0.2 | 4.7 | REACTOME GAP JUNCTION DEGRADATION | Genes involved in Gap junction degradation |
0.2 | 3.9 | REACTOME CHONDROITIN SULFATE BIOSYNTHESIS | Genes involved in Chondroitin sulfate biosynthesis |
0.2 | 3.6 | REACTOME SIGNAL ATTENUATION | Genes involved in Signal attenuation |
0.2 | 6.1 | REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS | Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers |
0.2 | 8.2 | REACTOME NCAM1 INTERACTIONS | Genes involved in NCAM1 interactions |
0.1 | 4.5 | REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
0.1 | 1.3 | REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY | Genes involved in Adenylate cyclase activating pathway |
0.1 | 5.1 | REACTOME O LINKED GLYCOSYLATION OF MUCINS | Genes involved in O-linked glycosylation of mucins |
0.1 | 6.2 | REACTOME MEIOTIC SYNAPSIS | Genes involved in Meiotic Synapsis |
0.1 | 1.2 | REACTOME PURINE SALVAGE | Genes involved in Purine salvage |
0.1 | 2.8 | REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
0.1 | 0.8 | REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION | Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression |
0.1 | 1.4 | REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 | Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1) |
0.1 | 2.0 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
0.1 | 0.8 | REACTOME PLATELET CALCIUM HOMEOSTASIS | Genes involved in Platelet calcium homeostasis |
0.1 | 0.6 | REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE | Genes involved in Regulation of Insulin Secretion by Acetylcholine |
0.1 | 0.8 | REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS | Genes involved in Facilitative Na+-independent glucose transporters |
0.0 | 1.1 | REACTOME G0 AND EARLY G1 | Genes involved in G0 and Early G1 |
0.0 | 6.9 | REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION | Genes involved in Factors involved in megakaryocyte development and platelet production |
0.0 | 1.8 | REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S | Genes involved in Activation of Chaperone Genes by XBP1(S) |
0.0 | 1.8 | REACTOME MRNA 3 END PROCESSING | Genes involved in mRNA 3'-end processing |
0.0 | 2.4 | REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
0.0 | 0.5 | REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
0.0 | 0.8 | REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
0.0 | 1.4 | REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
0.0 | 3.0 | REACTOME PEPTIDE CHAIN ELONGATION | Genes involved in Peptide chain elongation |
0.0 | 0.5 | REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA | Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha |
0.0 | 0.6 | REACTOME NEPHRIN INTERACTIONS | Genes involved in Nephrin interactions |
0.0 | 0.9 | REACTOME HS GAG BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
0.0 | 0.4 | REACTOME HDL MEDIATED LIPID TRANSPORT | Genes involved in HDL-mediated lipid transport |
0.0 | 0.5 | REACTOME RNA POL I TRANSCRIPTION TERMINATION | Genes involved in RNA Polymerase I Transcription Termination |
0.0 | 0.2 | REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 | Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0) |
0.0 | 0.5 | REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING | Genes involved in Transferrin endocytosis and recycling |
0.0 | 1.0 | REACTOME NRAGE SIGNALS DEATH THROUGH JNK | Genes involved in NRAGE signals death through JNK |
0.0 | 2.8 | REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |