avrg: GSE58827: Dynamics of the Mouse Liver
Gene Symbol | Gene ID | Gene Info |
---|---|---|
Hmx1
|
ENSMUSG00000067438.3 | H6 homeobox 1 |
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Hmx1 | mm10_v2_chr5_+_35388844_35388882 | 0.32 | 6.0e-02 | Click! |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
4.4 | 13.2 | GO:0072382 | minus-end-directed vesicle transport along microtubule(GO:0072382) |
3.5 | 10.4 | GO:0003330 | regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331) |
2.7 | 8.1 | GO:0051714 | regulation of cytolysis in other organism(GO:0051710) positive regulation of cytolysis in other organism(GO:0051714) |
2.2 | 6.5 | GO:1905000 | regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000) |
1.9 | 5.6 | GO:0070650 | actin filament bundle distribution(GO:0070650) |
1.8 | 16.5 | GO:0070944 | neutrophil mediated killing of bacterium(GO:0070944) |
1.6 | 4.8 | GO:0045660 | positive regulation of neutrophil differentiation(GO:0045660) |
1.0 | 4.2 | GO:1903896 | positive regulation of IRE1-mediated unfolded protein response(GO:1903896) |
0.9 | 3.7 | GO:1902953 | positive regulation of ER to Golgi vesicle-mediated transport(GO:1902953) positive regulation of endocytic recycling(GO:2001137) |
0.9 | 4.5 | GO:0008626 | granzyme-mediated apoptotic signaling pathway(GO:0008626) |
0.9 | 1.8 | GO:0097212 | lysosomal membrane organization(GO:0097212) |
0.7 | 2.2 | GO:0071492 | cellular response to UV-A(GO:0071492) response to dithiothreitol(GO:0072720) |
0.7 | 3.6 | GO:0006177 | GMP biosynthetic process(GO:0006177) |
0.7 | 3.4 | GO:0033277 | abortive mitotic cell cycle(GO:0033277) |
0.7 | 10.8 | GO:0071688 | striated muscle myosin thick filament assembly(GO:0071688) |
0.7 | 2.7 | GO:0002025 | vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025) |
0.7 | 2.6 | GO:0032053 | ciliary basal body organization(GO:0032053) |
0.7 | 2.0 | GO:0071603 | negative regulation of SMAD protein import into nucleus(GO:0060392) endothelial cell-cell adhesion(GO:0071603) negative regulation of sensory perception of pain(GO:1904057) bone regeneration(GO:1990523) |
0.6 | 3.8 | GO:0045905 | translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905) |
0.5 | 2.7 | GO:0043456 | regulation of pentose-phosphate shunt(GO:0043456) |
0.5 | 4.8 | GO:0070314 | G1 to G0 transition(GO:0070314) |
0.5 | 2.4 | GO:0090191 | negative regulation of branching involved in ureteric bud morphogenesis(GO:0090191) |
0.5 | 1.9 | GO:0051885 | positive regulation of anagen(GO:0051885) |
0.4 | 3.4 | GO:0051388 | positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388) |
0.4 | 12.2 | GO:0045780 | positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852) |
0.4 | 1.6 | GO:0021943 | formation of radial glial scaffolds(GO:0021943) |
0.4 | 5.0 | GO:0070995 | NADPH oxidation(GO:0070995) |
0.4 | 1.1 | GO:1901079 | positive regulation of relaxation of muscle(GO:1901079) |
0.4 | 2.8 | GO:0030263 | apoptotic chromosome condensation(GO:0030263) |
0.3 | 3.5 | GO:0019336 | phenol-containing compound catabolic process(GO:0019336) |
0.3 | 1.4 | GO:0018197 | peptidyl-aspartic acid modification(GO:0018197) |
0.3 | 1.0 | GO:0034093 | positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184) |
0.3 | 6.3 | GO:0032463 | negative regulation of protein homooligomerization(GO:0032463) |
0.3 | 1.0 | GO:0099526 | presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526) |
0.3 | 0.9 | GO:0030208 | dermatan sulfate biosynthetic process(GO:0030208) |
0.3 | 0.9 | GO:0061642 | chemoattraction of axon(GO:0061642) |
0.3 | 2.5 | GO:0036309 | protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371) |
0.3 | 1.4 | GO:1901252 | regulation of intracellular transport of viral material(GO:1901252) |
0.3 | 2.1 | GO:0060753 | regulation of mast cell chemotaxis(GO:0060753) |
0.3 | 2.1 | GO:0016576 | histone dephosphorylation(GO:0016576) |
0.3 | 2.9 | GO:0031914 | negative regulation of synaptic plasticity(GO:0031914) |
0.3 | 1.3 | GO:1904996 | positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996) |
0.2 | 1.2 | GO:0023041 | neuronal signal transduction(GO:0023041) |
0.2 | 3.0 | GO:0071481 | cellular response to X-ray(GO:0071481) |
0.2 | 3.9 | GO:0006968 | cellular defense response(GO:0006968) |
0.2 | 1.4 | GO:0031133 | regulation of axon diameter(GO:0031133) |
0.2 | 1.4 | GO:0048842 | positive regulation of axon extension involved in axon guidance(GO:0048842) |
0.2 | 1.5 | GO:0070494 | regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495) |
0.2 | 0.8 | GO:0070889 | platelet alpha granule organization(GO:0070889) |
0.2 | 2.2 | GO:0035878 | nail development(GO:0035878) |
0.2 | 1.8 | GO:0019673 | GDP-mannose metabolic process(GO:0019673) |
0.2 | 2.9 | GO:0000083 | regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083) |
0.2 | 4.2 | GO:0060707 | trophoblast giant cell differentiation(GO:0060707) |
0.2 | 1.3 | GO:0036006 | response to macrophage colony-stimulating factor(GO:0036005) cellular response to macrophage colony-stimulating factor stimulus(GO:0036006) |
0.2 | 0.8 | GO:2000774 | positive regulation of cellular senescence(GO:2000774) |
0.2 | 0.3 | GO:0014722 | regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722) |
0.2 | 2.3 | GO:0071361 | cellular response to ethanol(GO:0071361) |
0.1 | 1.8 | GO:0071578 | zinc II ion transmembrane import(GO:0071578) |
0.1 | 1.7 | GO:2000270 | negative regulation of fibroblast apoptotic process(GO:2000270) |
0.1 | 7.0 | GO:0010883 | regulation of lipid storage(GO:0010883) |
0.1 | 0.8 | GO:0032483 | regulation of Rab protein signal transduction(GO:0032483) |
0.1 | 2.3 | GO:0031987 | locomotion involved in locomotory behavior(GO:0031987) |
0.1 | 1.2 | GO:0048386 | positive regulation of retinoic acid receptor signaling pathway(GO:0048386) |
0.1 | 1.0 | GO:0044337 | canonical Wnt signaling pathway involved in positive regulation of apoptotic process(GO:0044337) positive regulation of protein localization to centrosome(GO:1904781) |
0.1 | 3.3 | GO:0048026 | positive regulation of mRNA splicing, via spliceosome(GO:0048026) |
0.1 | 0.6 | GO:0072383 | plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386) |
0.1 | 8.3 | GO:0048747 | muscle fiber development(GO:0048747) |
0.1 | 1.1 | GO:0045084 | positive regulation of interleukin-12 biosynthetic process(GO:0045084) |
0.1 | 5.1 | GO:0030199 | collagen fibril organization(GO:0030199) |
0.1 | 2.1 | GO:0048172 | regulation of short-term neuronal synaptic plasticity(GO:0048172) |
0.1 | 1.0 | GO:0032264 | IMP salvage(GO:0032264) |
0.1 | 1.9 | GO:0070831 | basement membrane assembly(GO:0070831) |
0.1 | 1.7 | GO:0050901 | leukocyte tethering or rolling(GO:0050901) |
0.1 | 0.9 | GO:0006362 | transcription elongation from RNA polymerase I promoter(GO:0006362) |
0.1 | 0.8 | GO:0010606 | positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606) |
0.1 | 3.3 | GO:0000154 | rRNA modification(GO:0000154) |
0.1 | 2.2 | GO:0044458 | motile cilium assembly(GO:0044458) |
0.1 | 0.3 | GO:0017185 | peptidyl-lysine hydroxylation(GO:0017185) |
0.1 | 1.6 | GO:0032274 | gonadotropin secretion(GO:0032274) |
0.1 | 3.0 | GO:0048791 | calcium ion-regulated exocytosis of neurotransmitter(GO:0048791) |
0.1 | 2.6 | GO:0046827 | positive regulation of protein export from nucleus(GO:0046827) |
0.1 | 0.4 | GO:1900042 | positive regulation of interleukin-2 secretion(GO:1900042) |
0.1 | 0.3 | GO:0060830 | ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830) |
0.1 | 5.5 | GO:0038083 | peptidyl-tyrosine autophosphorylation(GO:0038083) |
0.1 | 2.8 | GO:0007339 | binding of sperm to zona pellucida(GO:0007339) |
0.1 | 1.1 | GO:0080182 | histone H3-K4 trimethylation(GO:0080182) |
0.1 | 2.1 | GO:0031424 | keratinization(GO:0031424) |
0.1 | 1.0 | GO:0000338 | protein deneddylation(GO:0000338) |
0.1 | 2.0 | GO:0045879 | negative regulation of smoothened signaling pathway(GO:0045879) |
0.1 | 3.4 | GO:0006911 | phagocytosis, engulfment(GO:0006911) |
0.1 | 0.3 | GO:0015015 | heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015) |
0.1 | 0.6 | GO:0048711 | positive regulation of astrocyte differentiation(GO:0048711) |
0.1 | 0.8 | GO:0033523 | histone H2B ubiquitination(GO:0033523) |
0.1 | 0.6 | GO:0031268 | pseudopodium organization(GO:0031268) |
0.0 | 1.4 | GO:2000369 | regulation of clathrin-mediated endocytosis(GO:2000369) |
0.0 | 0.9 | GO:0032331 | negative regulation of chondrocyte differentiation(GO:0032331) |
0.0 | 1.7 | GO:0050853 | B cell receptor signaling pathway(GO:0050853) |
0.0 | 1.6 | GO:0003016 | respiratory system process(GO:0003016) |
0.0 | 0.2 | GO:1902525 | regulation of protein monoubiquitination(GO:1902525) |
0.0 | 0.5 | GO:0050930 | induction of positive chemotaxis(GO:0050930) |
0.0 | 1.7 | GO:0009954 | proximal/distal pattern formation(GO:0009954) |
0.0 | 1.0 | GO:0006817 | phosphate ion transport(GO:0006817) |
0.0 | 0.4 | GO:0071044 | histone mRNA catabolic process(GO:0071044) RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503) |
0.0 | 3.9 | GO:0043627 | response to estrogen(GO:0043627) |
0.0 | 1.7 | GO:0006611 | protein export from nucleus(GO:0006611) |
0.0 | 1.8 | GO:0045737 | positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) |
0.0 | 0.9 | GO:1903077 | cortical actin cytoskeleton organization(GO:0030866) negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376) |
0.0 | 3.2 | GO:0043154 | negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154) |
0.0 | 0.5 | GO:0008090 | retrograde axonal transport(GO:0008090) |
0.0 | 0.7 | GO:0000028 | ribosomal small subunit assembly(GO:0000028) |
0.0 | 0.3 | GO:0000963 | mitochondrial RNA processing(GO:0000963) |
0.0 | 0.1 | GO:1905034 | regulation of antifungal innate immune response(GO:1905034) negative regulation of antifungal innate immune response(GO:1905035) |
0.0 | 2.4 | GO:0048477 | oogenesis(GO:0048477) |
0.0 | 0.8 | GO:0043551 | regulation of phosphatidylinositol 3-kinase activity(GO:0043551) |
0.0 | 0.1 | GO:0050960 | detection of temperature stimulus involved in thermoception(GO:0050960) response to capsazepine(GO:1901594) |
0.0 | 0.1 | GO:0006685 | sphingomyelin catabolic process(GO:0006685) |
0.0 | 0.5 | GO:0046854 | phosphatidylinositol phosphorylation(GO:0046854) |
0.0 | 0.6 | GO:0006198 | cAMP catabolic process(GO:0006198) |
0.0 | 0.5 | GO:0043153 | entrainment of circadian clock by photoperiod(GO:0043153) |
0.0 | 1.2 | GO:0051865 | protein autoubiquitination(GO:0051865) |
0.0 | 1.0 | GO:0048678 | response to axon injury(GO:0048678) |
0.0 | 1.1 | GO:0070527 | platelet aggregation(GO:0070527) |
0.0 | 4.2 | GO:0007018 | microtubule-based movement(GO:0007018) |
0.0 | 0.1 | GO:0060536 | cartilage morphogenesis(GO:0060536) |
0.0 | 0.1 | GO:1903025 | regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025) |
0.0 | 0.2 | GO:0007175 | negative regulation of epidermal growth factor-activated receptor activity(GO:0007175) |
0.0 | 0.1 | GO:0051694 | pointed-end actin filament capping(GO:0051694) |
0.0 | 0.4 | GO:0051930 | regulation of sensory perception of pain(GO:0051930) regulation of sensory perception(GO:0051931) |
0.0 | 2.6 | GO:0030217 | T cell differentiation(GO:0030217) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.3 | 6.5 | GO:0031523 | Myb complex(GO:0031523) |
0.9 | 5.6 | GO:0097513 | myosin II filament(GO:0097513) |
0.8 | 3.0 | GO:0097129 | cyclin D2-CDK4 complex(GO:0097129) |
0.6 | 12.8 | GO:0031616 | spindle pole centrosome(GO:0031616) |
0.5 | 3.3 | GO:0031428 | box C/D snoRNP complex(GO:0031428) |
0.4 | 10.8 | GO:0005859 | muscle myosin complex(GO:0005859) |
0.4 | 3.4 | GO:0042105 | alpha-beta T cell receptor complex(GO:0042105) |
0.3 | 1.0 | GO:0005607 | laminin-2 complex(GO:0005607) |
0.3 | 2.8 | GO:0061574 | ASAP complex(GO:0061574) |
0.3 | 4.8 | GO:0031618 | nuclear pericentric heterochromatin(GO:0031618) |
0.3 | 4.5 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
0.3 | 0.8 | GO:0031251 | PAN complex(GO:0031251) |
0.3 | 1.4 | GO:0031166 | integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310) |
0.3 | 1.1 | GO:0008282 | ATP-sensitive potassium channel complex(GO:0008282) |
0.3 | 1.0 | GO:0005944 | phosphatidylinositol 3-kinase complex, class IB(GO:0005944) |
0.3 | 4.8 | GO:0031045 | dense core granule(GO:0031045) |
0.3 | 5.0 | GO:0044224 | juxtaparanode region of axon(GO:0044224) |
0.2 | 3.9 | GO:0032045 | guanyl-nucleotide exchange factor complex(GO:0032045) |
0.2 | 2.1 | GO:0032591 | dendritic spine membrane(GO:0032591) |
0.2 | 14.4 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
0.2 | 1.0 | GO:0034750 | Scrib-APC-beta-catenin complex(GO:0034750) |
0.2 | 1.1 | GO:0072357 | PTW/PP1 phosphatase complex(GO:0072357) |
0.1 | 1.0 | GO:0030915 | Smc5-Smc6 complex(GO:0030915) |
0.1 | 0.4 | GO:0044299 | C-fiber(GO:0044299) |
0.1 | 1.6 | GO:1990907 | beta-catenin-TCF complex(GO:1990907) |
0.1 | 3.5 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
0.1 | 2.7 | GO:0030056 | hemidesmosome(GO:0030056) |
0.1 | 1.8 | GO:0031258 | lamellipodium membrane(GO:0031258) |
0.1 | 1.4 | GO:0071439 | clathrin complex(GO:0071439) |
0.1 | 2.2 | GO:0044292 | dendrite terminus(GO:0044292) |
0.1 | 7.1 | GO:0005871 | kinesin complex(GO:0005871) |
0.1 | 2.3 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
0.1 | 4.1 | GO:0008180 | COP9 signalosome(GO:0008180) |
0.1 | 1.8 | GO:0016580 | Sin3 complex(GO:0016580) |
0.1 | 2.5 | GO:0031430 | M band(GO:0031430) |
0.1 | 0.6 | GO:0035749 | myelin sheath adaxonal region(GO:0035749) |
0.1 | 0.8 | GO:0016593 | Cdc73/Paf1 complex(GO:0016593) |
0.1 | 5.5 | GO:0031519 | PcG protein complex(GO:0031519) |
0.1 | 5.1 | GO:0009925 | basal plasma membrane(GO:0009925) |
0.1 | 0.9 | GO:0045180 | basal cortex(GO:0045180) |
0.1 | 2.1 | GO:0001533 | cornified envelope(GO:0001533) |
0.1 | 5.0 | GO:0016528 | sarcoplasm(GO:0016528) |
0.1 | 3.5 | GO:0005844 | polysome(GO:0005844) |
0.1 | 4.9 | GO:0005643 | nuclear pore(GO:0005643) |
0.1 | 2.0 | GO:0030131 | clathrin adaptor complex(GO:0030131) |
0.0 | 1.7 | GO:0044665 | MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339) |
0.0 | 0.8 | GO:0017101 | aminoacyl-tRNA synthetase multienzyme complex(GO:0017101) |
0.0 | 1.7 | GO:0008305 | integrin complex(GO:0008305) |
0.0 | 3.6 | GO:0031903 | peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903) |
0.0 | 1.9 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
0.0 | 1.8 | GO:0032809 | neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298) |
0.0 | 0.6 | GO:0031143 | pseudopodium(GO:0031143) |
0.0 | 0.8 | GO:0030665 | clathrin-coated vesicle membrane(GO:0030665) |
0.0 | 3.8 | GO:0005581 | collagen trimer(GO:0005581) |
0.0 | 5.6 | GO:0005884 | actin filament(GO:0005884) |
0.0 | 1.2 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
0.0 | 1.8 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
0.0 | 2.6 | GO:0005814 | centriole(GO:0005814) |
0.0 | 2.9 | GO:0000922 | spindle pole(GO:0000922) |
0.0 | 3.0 | GO:0031234 | extrinsic component of cytoplasmic side of plasma membrane(GO:0031234) |
0.0 | 8.6 | GO:0005667 | transcription factor complex(GO:0005667) |
0.0 | 0.7 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
0.0 | 0.8 | GO:0031901 | early endosome membrane(GO:0031901) |
0.0 | 1.2 | GO:0016605 | PML body(GO:0016605) |
0.0 | 0.3 | GO:0005689 | U12-type spliceosomal complex(GO:0005689) |
0.0 | 18.4 | GO:0005615 | extracellular space(GO:0005615) |
0.0 | 0.3 | GO:0072686 | mitotic spindle(GO:0072686) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.6 | 8.1 | GO:0008745 | N-acetylmuramoyl-L-alanine amidase activity(GO:0008745) peptidoglycan receptor activity(GO:0016019) |
1.3 | 6.5 | GO:0034988 | Fc-gamma receptor I complex binding(GO:0034988) |
1.2 | 3.5 | GO:0004800 | thyroxine 5'-deiodinase activity(GO:0004800) |
1.1 | 3.2 | GO:0015319 | sodium:inorganic phosphate symporter activity(GO:0015319) |
0.9 | 3.6 | GO:0003938 | IMP dehydrogenase activity(GO:0003938) |
0.9 | 2.7 | GO:0046538 | bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538) |
0.7 | 2.7 | GO:0004939 | beta-adrenergic receptor activity(GO:0004939) bradykinin receptor binding(GO:0031711) |
0.6 | 10.8 | GO:0097493 | structural molecule activity conferring elasticity(GO:0097493) |
0.5 | 2.1 | GO:0061575 | cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575) |
0.5 | 3.4 | GO:0005001 | transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198) |
0.5 | 13.2 | GO:0008569 | ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569) |
0.5 | 1.4 | GO:0035373 | chondroitin sulfate proteoglycan binding(GO:0035373) |
0.4 | 2.1 | GO:0030280 | structural constituent of epidermis(GO:0030280) |
0.4 | 2.1 | GO:1990829 | C-rich single-stranded DNA binding(GO:1990829) |
0.3 | 3.7 | GO:0030306 | ADP-ribosylation factor binding(GO:0030306) |
0.3 | 2.2 | GO:0038132 | neuregulin binding(GO:0038132) |
0.3 | 1.2 | GO:0001847 | opsonin receptor activity(GO:0001847) |
0.3 | 5.6 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
0.3 | 1.9 | GO:0008467 | [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467) |
0.3 | 4.2 | GO:0002162 | dystroglycan binding(GO:0002162) |
0.2 | 0.9 | GO:1902379 | chemoattractant activity involved in axon guidance(GO:1902379) |
0.2 | 10.0 | GO:0070412 | R-SMAD binding(GO:0070412) |
0.2 | 2.2 | GO:0050291 | sphingosine N-acyltransferase activity(GO:0050291) |
0.2 | 8.0 | GO:0030506 | ankyrin binding(GO:0030506) |
0.2 | 1.6 | GO:0030284 | estrogen receptor activity(GO:0030284) |
0.2 | 1.7 | GO:0046935 | 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935) |
0.2 | 3.3 | GO:1990226 | histone methyltransferase binding(GO:1990226) |
0.2 | 5.0 | GO:0004033 | aldo-keto reductase (NADP) activity(GO:0004033) |
0.2 | 4.4 | GO:0019956 | chemokine binding(GO:0019956) |
0.2 | 0.9 | GO:0001537 | N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537) |
0.2 | 1.3 | GO:0048101 | calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101) |
0.2 | 0.9 | GO:0001165 | RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165) |
0.2 | 5.6 | GO:0008187 | poly-pyrimidine tract binding(GO:0008187) |
0.2 | 1.0 | GO:0019784 | NEDD8-specific protease activity(GO:0019784) |
0.2 | 1.7 | GO:0042609 | CD4 receptor binding(GO:0042609) |
0.2 | 3.8 | GO:0003746 | translation elongation factor activity(GO:0003746) |
0.1 | 3.3 | GO:0035613 | RNA stem-loop binding(GO:0035613) |
0.1 | 2.3 | GO:0004016 | adenylate cyclase activity(GO:0004016) |
0.1 | 1.2 | GO:0019966 | interleukin-1 binding(GO:0019966) |
0.1 | 2.9 | GO:0001618 | virus receptor activity(GO:0001618) |
0.1 | 2.9 | GO:0032794 | GTPase activating protein binding(GO:0032794) |
0.1 | 0.9 | GO:0008508 | bile acid:sodium symporter activity(GO:0008508) |
0.1 | 1.0 | GO:0016618 | hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267) |
0.1 | 7.0 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
0.1 | 1.0 | GO:0047623 | AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623) |
0.1 | 2.8 | GO:0005520 | insulin-like growth factor binding(GO:0005520) |
0.1 | 0.3 | GO:0034437 | glycoprotein transporter activity(GO:0034437) |
0.1 | 7.1 | GO:0003777 | microtubule motor activity(GO:0003777) |
0.1 | 0.6 | GO:0015129 | lactate transmembrane transporter activity(GO:0015129) |
0.1 | 1.7 | GO:0070016 | armadillo repeat domain binding(GO:0070016) |
0.1 | 18.3 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
0.1 | 1.1 | GO:0045294 | alpha-catenin binding(GO:0045294) |
0.1 | 5.5 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
0.1 | 3.2 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
0.1 | 1.4 | GO:0035612 | AP-2 adaptor complex binding(GO:0035612) |
0.1 | 1.0 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
0.1 | 3.2 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
0.1 | 0.9 | GO:0005522 | profilin binding(GO:0005522) |
0.1 | 0.3 | GO:0017095 | heparan sulfate 6-O-sulfotransferase activity(GO:0017095) |
0.1 | 2.8 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
0.1 | 1.8 | GO:0001222 | transcription corepressor binding(GO:0001222) |
0.1 | 0.4 | GO:0051880 | G-quadruplex RNA binding(GO:0002151) G-quadruplex DNA binding(GO:0051880) |
0.1 | 5.2 | GO:0003727 | single-stranded RNA binding(GO:0003727) |
0.1 | 1.0 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
0.1 | 0.6 | GO:0033691 | sialic acid binding(GO:0033691) |
0.1 | 6.6 | GO:0003697 | single-stranded DNA binding(GO:0003697) |
0.1 | 3.2 | GO:0043027 | cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) |
0.1 | 1.4 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
0.1 | 0.6 | GO:0001135 | transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135) |
0.1 | 0.5 | GO:0043426 | MRF binding(GO:0043426) |
0.1 | 3.5 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
0.1 | 0.8 | GO:0004535 | poly(A)-specific ribonuclease activity(GO:0004535) |
0.1 | 1.8 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
0.1 | 1.7 | GO:0042169 | SH2 domain binding(GO:0042169) |
0.0 | 1.7 | GO:0008536 | Ran GTPase binding(GO:0008536) |
0.0 | 1.9 | GO:0005109 | frizzled binding(GO:0005109) |
0.0 | 1.0 | GO:0019789 | SUMO transferase activity(GO:0019789) |
0.0 | 1.3 | GO:0035035 | histone acetyltransferase binding(GO:0035035) |
0.0 | 1.8 | GO:0016836 | hydro-lyase activity(GO:0016836) |
0.0 | 0.7 | GO:0097602 | cullin family protein binding(GO:0097602) |
0.0 | 0.3 | GO:0034450 | ubiquitin-ubiquitin ligase activity(GO:0034450) |
0.0 | 1.5 | GO:0030507 | spectrin binding(GO:0030507) |
0.0 | 0.6 | GO:0031489 | myosin V binding(GO:0031489) |
0.0 | 0.7 | GO:0005035 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
0.0 | 0.6 | GO:0042162 | telomeric DNA binding(GO:0042162) |
0.0 | 1.1 | GO:0032266 | phosphatidylinositol-3-phosphate binding(GO:0032266) |
0.0 | 5.5 | GO:0001227 | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227) |
0.0 | 0.6 | GO:0004115 | 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) |
0.0 | 0.8 | GO:0004364 | glutathione transferase activity(GO:0004364) |
0.0 | 0.6 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
0.0 | 1.1 | GO:0019905 | syntaxin binding(GO:0019905) |
0.0 | 0.1 | GO:0097603 | temperature-gated ion channel activity(GO:0097603) |
0.0 | 0.1 | GO:0004767 | sphingomyelin phosphodiesterase activity(GO:0004767) |
0.0 | 0.4 | GO:0000993 | RNA polymerase II core binding(GO:0000993) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 16.0 | PID UPA UPAR PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
0.3 | 15.1 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
0.2 | 3.2 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
0.2 | 3.2 | PID TCR JNK PATHWAY | JNK signaling in the CD4+ TCR pathway |
0.2 | 13.8 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
0.2 | 8.5 | PID IL8 CXCR2 PATHWAY | IL8- and CXCR2-mediated signaling events |
0.2 | 2.9 | SA REG CASCADE OF CYCLIN EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
0.1 | 2.3 | PID LPA4 PATHWAY | LPA4-mediated signaling events |
0.1 | 1.7 | PID INTEGRIN5 PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
0.1 | 3.6 | PID ERBB1 RECEPTOR PROXIMAL PATHWAY | EGF receptor (ErbB1) signaling pathway |
0.1 | 1.5 | PID P38 GAMMA DELTA PATHWAY | Signaling mediated by p38-gamma and p38-delta |
0.1 | 2.9 | SA B CELL RECEPTOR COMPLEXES | Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases. |
0.1 | 2.3 | PID IL27 PATHWAY | IL27-mediated signaling events |
0.1 | 3.0 | PID IL2 STAT5 PATHWAY | IL2 signaling events mediated by STAT5 |
0.1 | 3.4 | PID RAC1 PATHWAY | RAC1 signaling pathway |
0.1 | 2.4 | PID ARF6 PATHWAY | Arf6 signaling events |
0.1 | 4.2 | PID FCER1 PATHWAY | Fc-epsilon receptor I signaling in mast cells |
0.1 | 2.1 | PID FOXM1 PATHWAY | FOXM1 transcription factor network |
0.1 | 2.8 | PID ATF2 PATHWAY | ATF-2 transcription factor network |
0.1 | 3.3 | PID NFAT TFPATHWAY | Calcineurin-regulated NFAT-dependent transcription in lymphocytes |
0.1 | 4.8 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
0.1 | 1.0 | PID EPHA FWDPATHWAY | EPHA forward signaling |
0.0 | 1.0 | ST GRANULE CELL SURVIVAL PATHWAY | Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway. |
0.0 | 1.8 | PID HIF2PATHWAY | HIF-2-alpha transcription factor network |
0.0 | 4.2 | PID BETA CATENIN NUC PATHWAY | Regulation of nuclear beta catenin signaling and target gene transcription |
0.0 | 0.9 | PID INSULIN GLUCOSE PATHWAY | Insulin-mediated glucose transport |
0.0 | 0.8 | PID ERBB1 INTERNALIZATION PATHWAY | Internalization of ErbB1 |
0.0 | 1.4 | PID ERBB1 DOWNSTREAM PATHWAY | ErbB1 downstream signaling |
0.0 | 0.7 | PID CD8 TCR DOWNSTREAM PATHWAY | Downstream signaling in naïve CD8+ T cells |
0.0 | 3.9 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
0.0 | 0.6 | PID IL4 2PATHWAY | IL4-mediated signaling events |
0.0 | 0.5 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.8 | 16.5 | REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
0.5 | 13.2 | REACTOME KINESINS | Genes involved in Kinesins |
0.3 | 12.7 | REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS | Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus |
0.3 | 8.6 | REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
0.2 | 7.9 | REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |
0.2 | 3.4 | REACTOME REGULATION OF IFNG SIGNALING | Genes involved in Regulation of IFNG signaling |
0.2 | 7.7 | REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS | Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis |
0.2 | 3.5 | REACTOME AMINE DERIVED HORMONES | Genes involved in Amine-derived hormones |
0.2 | 2.4 | REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
0.2 | 2.3 | REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY | Genes involved in Adenylate cyclase activating pathway |
0.2 | 3.2 | REACTOME GENERATION OF SECOND MESSENGER MOLECULES | Genes involved in Generation of second messenger molecules |
0.1 | 5.7 | REACTOME G1 PHASE | Genes involved in G1 Phase |
0.1 | 3.8 | REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION | Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation |
0.1 | 3.2 | REACTOME ERK MAPK TARGETS | Genes involved in ERK/MAPK targets |
0.1 | 8.0 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
0.1 | 5.0 | REACTOME VOLTAGE GATED POTASSIUM CHANNELS | Genes involved in Voltage gated Potassium channels |
0.1 | 1.9 | REACTOME SIGNALING BY NODAL | Genes involved in Signaling by NODAL |
0.1 | 1.8 | REACTOME ZINC TRANSPORTERS | Genes involved in Zinc transporters |
0.1 | 1.0 | REACTOME P38MAPK EVENTS | Genes involved in p38MAPK events |
0.1 | 2.7 | REACTOME AMINE LIGAND BINDING RECEPTORS | Genes involved in Amine ligand-binding receptors |
0.1 | 1.0 | REACTOME CTNNB1 PHOSPHORYLATION CASCADE | Genes involved in Beta-catenin phosphorylation cascade |
0.1 | 2.8 | REACTOME TIGHT JUNCTION INTERACTIONS | Genes involved in Tight junction interactions |
0.1 | 2.8 | REACTOME CELL JUNCTION ORGANIZATION | Genes involved in Cell junction organization |
0.1 | 2.2 | REACTOME HS GAG BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
0.1 | 1.4 | REACTOME OTHER SEMAPHORIN INTERACTIONS | Genes involved in Other semaphorin interactions |
0.1 | 1.0 | REACTOME PURINE SALVAGE | Genes involved in Purine salvage |
0.0 | 2.8 | REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS | Genes involved in Apoptotic cleavage of cellular proteins |
0.0 | 0.6 | REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
0.0 | 1.7 | REACTOME GPVI MEDIATED ACTIVATION CASCADE | Genes involved in GPVI-mediated activation cascade |
0.0 | 1.7 | REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
0.0 | 0.9 | REACTOME RNA POL I TRANSCRIPTION TERMINATION | Genes involved in RNA Polymerase I Transcription Termination |
0.0 | 1.3 | REACTOME CGMP EFFECTS | Genes involved in cGMP effects |
0.0 | 1.2 | REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS | Genes involved in Transport of Ribonucleoproteins into the Host Nucleus |
0.0 | 1.4 | REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT | Genes involved in ABC-family proteins mediated transport |
0.0 | 1.4 | REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
0.0 | 0.4 | REACTOME DESTABILIZATION OF MRNA BY BRF1 | Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1) |
0.0 | 0.8 | REACTOME CYTOSOLIC TRNA AMINOACYLATION | Genes involved in Cytosolic tRNA aminoacylation |
0.0 | 0.9 | REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM | Genes involved in Chondroitin sulfate/dermatan sulfate metabolism |
0.0 | 0.6 | REACTOME BASIGIN INTERACTIONS | Genes involved in Basigin interactions |
0.0 | 0.5 | REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION | Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression |
0.0 | 2.1 | REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
0.0 | 0.7 | REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |