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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Esrrb_Esrra

Z-value: 0.94

Motif logo

Transcription factors associated with Esrrb_Esrra

Gene Symbol Gene ID Gene Info
ENSMUSG00000021255.11 estrogen related receptor, beta
ENSMUSG00000024955.7 estrogen related receptor, alpha

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Esrramm10_v2_chr19_-_6921804_69218340.521.1e-03Click!
Esrrbmm10_v2_chr12_+_86361112_863611310.173.3e-01Click!

Activity profile of Esrrb_Esrra motif

Sorted Z-values of Esrrb_Esrra motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Esrrb_Esrra

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.2 GO:0006106 fumarate metabolic process(GO:0006106)
0.9 2.8 GO:0021933 radial glia guided migration of cerebellar granule cell(GO:0021933)
0.3 1.5 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.3 0.8 GO:0071846 actin filament debranching(GO:0071846)
0.2 1.2 GO:1903059 regulation of protein lipidation(GO:1903059)
0.2 1.6 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.2 0.9 GO:0036022 limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.2 0.4 GO:0035461 vitamin transmembrane transport(GO:0035461)
0.2 1.0 GO:0015886 heme transport(GO:0015886)
0.2 1.1 GO:0006543 glutamine catabolic process(GO:0006543)
0.2 0.5 GO:1901079 positive regulation of relaxation of muscle(GO:1901079)
0.2 0.5 GO:0070256 positive regulation of nucleobase-containing compound transport(GO:0032241) regulation of nucleoside transport(GO:0032242) negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256)
0.2 1.5 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.2 1.0 GO:0006172 ADP biosynthetic process(GO:0006172)
0.2 1.4 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.2 0.5 GO:1902445 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
0.1 0.1 GO:0001698 gastrin-induced gastric acid secretion(GO:0001698)
0.1 0.9 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.1 0.1 GO:1990379 lipid transport across blood brain barrier(GO:1990379)
0.1 2.0 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.1 0.6 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
0.1 1.2 GO:0009644 response to high light intensity(GO:0009644)
0.1 1.9 GO:0046884 follicle-stimulating hormone secretion(GO:0046884)
0.1 0.4 GO:0034635 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
0.1 0.6 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.1 0.4 GO:2000118 regulation of sodium-dependent phosphate transport(GO:2000118)
0.1 0.5 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982)
0.1 0.3 GO:0061402 positive regulation of transcription from RNA polymerase II promoter in response to acidic pH(GO:0061402) regulation of glutamine transport(GO:2000485)
0.1 1.1 GO:0097461 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.1 1.4 GO:2000653 regulation of genetic imprinting(GO:2000653)
0.1 0.3 GO:0060166 olfactory pit development(GO:0060166)
0.1 0.3 GO:0052422 modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.1 0.3 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.1 0.1 GO:1900142 regulation of oligodendrocyte apoptotic process(GO:1900141) negative regulation of oligodendrocyte apoptotic process(GO:1900142)
0.1 0.4 GO:1902477 defense response to bacterium, incompatible interaction(GO:0009816) regulation of defense response to bacterium, incompatible interaction(GO:1902477)
0.1 0.3 GO:0030210 heparin biosynthetic process(GO:0030210)
0.1 1.0 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.1 0.9 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.1 0.6 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.1 0.6 GO:0006102 isocitrate metabolic process(GO:0006102)
0.1 0.1 GO:0061300 cerebellum vasculature development(GO:0061300)
0.1 0.3 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.1 0.3 GO:1901526 regulation of chemokine (C-C motif) ligand 5 production(GO:0071649) positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.1 0.3 GO:2001287 negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.1 0.6 GO:0019244 lactate biosynthetic process from pyruvate(GO:0019244)
0.1 0.2 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.1 0.3 GO:2000612 regulation of thyroid-stimulating hormone secretion(GO:2000612)
0.1 1.9 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 0.4 GO:0003100 regulation of systemic arterial blood pressure by endothelin(GO:0003100)
0.1 0.2 GO:0006108 malate metabolic process(GO:0006108)
0.1 0.3 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.1 1.6 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.1 1.7 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1 0.3 GO:0006572 tyrosine catabolic process(GO:0006572)
0.1 0.2 GO:0019043 establishment of viral latency(GO:0019043)
0.1 0.4 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
0.1 0.3 GO:0098886 modification of dendritic spine(GO:0098886)
0.1 0.1 GO:2000646 positive regulation of receptor catabolic process(GO:2000646)
0.1 0.2 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
0.1 0.3 GO:0000270 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253) negative regulation of natural killer cell differentiation(GO:0032824) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827)
0.1 0.7 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.1 0.3 GO:0072014 proximal tubule development(GO:0072014)
0.1 0.7 GO:0031937 positive regulation of chromatin silencing(GO:0031937)
0.1 0.1 GO:0021966 corticospinal neuron axon guidance(GO:0021966)
0.1 1.5 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 0.1 GO:0097212 lysosomal membrane organization(GO:0097212)
0.1 0.6 GO:0000255 allantoin metabolic process(GO:0000255)
0.1 0.1 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.1 0.1 GO:0072076 nephrogenic mesenchyme development(GO:0072076)
0.1 0.2 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.1 1.2 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.1 0.2 GO:0042560 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
0.1 0.4 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.0 1.3 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.1 GO:1903279 regulation of calcium:sodium antiporter activity(GO:1903279)
0.0 0.2 GO:0014734 skeletal muscle hypertrophy(GO:0014734)
0.0 0.2 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.0 0.3 GO:2000002 negative regulation of DNA damage checkpoint(GO:2000002)
0.0 0.4 GO:0016198 axon choice point recognition(GO:0016198)
0.0 0.5 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.5 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.0 0.3 GO:0002278 eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil degranulation(GO:0043308)
0.0 0.1 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.0 0.1 GO:0001983 baroreceptor response to increased systemic arterial blood pressure(GO:0001983)
0.0 0.1 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.0 0.3 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 0.2 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0 0.2 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.0 0.6 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.0 0.1 GO:0035672 oligopeptide transmembrane transport(GO:0035672)
0.0 0.2 GO:0072363 regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter(GO:0072363)
0.0 0.3 GO:0060763 mammary duct terminal end bud growth(GO:0060763)
0.0 0.0 GO:0050923 regulation of negative chemotaxis(GO:0050923)
0.0 0.3 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.0 0.1 GO:0002223 stimulatory C-type lectin receptor signaling pathway(GO:0002223)
0.0 0.1 GO:0033058 directional locomotion(GO:0033058)
0.0 0.1 GO:0006231 dTMP biosynthetic process(GO:0006231) dTMP metabolic process(GO:0046073)
0.0 0.2 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.6 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.1 GO:1903797 positive regulation of inorganic anion transmembrane transport(GO:1903797)
0.0 0.6 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.3 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.2 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.0 0.5 GO:0048733 sebaceous gland development(GO:0048733)
0.0 0.6 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.0 0.4 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.1 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.0 0.3 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.0 0.7 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.1 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.2 GO:0032237 activation of store-operated calcium channel activity(GO:0032237)
0.0 0.2 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.0 0.2 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 1.9 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0 0.1 GO:0034982 mitochondrial protein processing(GO:0034982)
0.0 0.1 GO:0045763 negative regulation of cellular amino acid metabolic process(GO:0045763)
0.0 0.1 GO:0042908 xenobiotic transport(GO:0042908)
0.0 0.4 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.0 0.1 GO:0045014 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.0 0.3 GO:0009438 methylglyoxal metabolic process(GO:0009438)
0.0 0.3 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.1 GO:0071798 response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.0 0.7 GO:0031065 positive regulation of histone deacetylation(GO:0031065)
0.0 0.1 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.0 0.2 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.0 0.4 GO:0048505 regulation of timing of cell differentiation(GO:0048505)
0.0 0.2 GO:0010694 positive regulation of alkaline phosphatase activity(GO:0010694)
0.0 0.0 GO:0061687 detoxification of inorganic compound(GO:0061687)
0.0 0.1 GO:0055099 response to high density lipoprotein particle(GO:0055099)
0.0 1.0 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.4 GO:0070633 transepithelial transport(GO:0070633)
0.0 0.1 GO:1903847 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849) regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.0 0.4 GO:0007220 Notch receptor processing(GO:0007220)
0.0 0.1 GO:0042891 antibiotic transport(GO:0042891)
0.0 0.1 GO:1902031 regulation of pentose-phosphate shunt(GO:0043456) regulation of NADP metabolic process(GO:1902031)
0.0 0.4 GO:0035376 sterol import(GO:0035376) cholesterol import(GO:0070508)
0.0 0.1 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.1 GO:1990000 amyloid fibril formation(GO:1990000)
0.0 0.1 GO:0002082 regulation of oxidative phosphorylation(GO:0002082)
0.0 0.1 GO:0002636 positive regulation of germinal center formation(GO:0002636)
0.0 0.8 GO:0009409 response to cold(GO:0009409)
0.0 0.1 GO:0070347 brown fat cell proliferation(GO:0070342) regulation of brown fat cell proliferation(GO:0070347)
0.0 0.2 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.2 GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372)
0.0 0.3 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.4 GO:0007614 short-term memory(GO:0007614)
0.0 0.1 GO:0070375 ERK5 cascade(GO:0070375)
0.0 0.4 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.1 GO:0010796 regulation of multivesicular body size(GO:0010796)
0.0 0.1 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372)
0.0 0.1 GO:1904672 regulation of somatic stem cell population maintenance(GO:1904672)
0.0 1.9 GO:0032091 negative regulation of protein binding(GO:0032091)
0.0 0.1 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.1 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.2 GO:0043981 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 0.1 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0 0.2 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.5 GO:0046688 response to copper ion(GO:0046688)
0.0 0.3 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.0 0.2 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.3 GO:0043457 regulation of cellular respiration(GO:0043457)
0.0 0.2 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.6 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 1.4 GO:0051453 regulation of intracellular pH(GO:0051453)
0.0 0.3 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.0 0.2 GO:0006264 mitochondrial DNA replication(GO:0006264)
0.0 0.2 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 0.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.1 GO:0060709 glycogen cell differentiation involved in embryonic placenta development(GO:0060709)
0.0 0.0 GO:0070476 rRNA (guanine-N7)-methylation(GO:0070476)
0.0 0.1 GO:0072530 purine-containing compound transmembrane transport(GO:0072530)
0.0 0.1 GO:0030432 peristalsis(GO:0030432)
0.0 0.2 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.1 GO:0070166 enamel mineralization(GO:0070166)
0.0 0.1 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.1 GO:0051660 establishment of centrosome localization(GO:0051660)
0.0 0.3 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.2 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.0 GO:0050812 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0 0.4 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.0 GO:0099624 atrial cardiac muscle cell membrane repolarization(GO:0099624)
0.0 0.2 GO:0051156 glucose 6-phosphate metabolic process(GO:0051156)
0.0 0.3 GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060)
0.0 0.3 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.0 0.1 GO:0071281 cellular response to iron ion(GO:0071281)
0.0 0.2 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.7 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
0.2 0.5 GO:0032010 phagolysosome(GO:0032010)
0.2 1.6 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.1 1.6 GO:0071439 clathrin complex(GO:0071439)
0.1 0.9 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.1 0.7 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.1 0.3 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
0.1 1.5 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.1 0.4 GO:0042583 chromaffin granule(GO:0042583)
0.1 2.6 GO:0042588 zymogen granule(GO:0042588)
0.1 0.3 GO:0045283 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.1 0.3 GO:0044393 microspike(GO:0044393)
0.1 0.8 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.1 0.4 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.1 0.2 GO:0005940 septin ring(GO:0005940)
0.1 0.7 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 0.4 GO:0045239 tricarboxylic acid cycle enzyme complex(GO:0045239)
0.1 0.7 GO:0001520 outer dense fiber(GO:0001520)
0.1 0.2 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.1 0.3 GO:0097226 sperm mitochondrial sheath(GO:0097226)
0.0 0.3 GO:0098645 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.0 0.2 GO:0017133 mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.0 0.3 GO:0097444 spine apparatus(GO:0097444)
0.0 0.2 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.0 0.5 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.0 0.4 GO:0005688 U6 snRNP(GO:0005688)
0.0 0.5 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.7 GO:0098798 mitochondrial protein complex(GO:0098798)
0.0 2.6 GO:0005844 polysome(GO:0005844)
0.0 0.9 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.1 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.0 0.6 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.7 GO:0032279 asymmetric synapse(GO:0032279)
0.0 0.2 GO:0070069 cytochrome complex(GO:0070069)
0.0 0.1 GO:0005745 m-AAA complex(GO:0005745)
0.0 0.2 GO:0035748 myelin sheath abaxonal region(GO:0035748)
0.0 0.7 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.2 GO:0008091 spectrin(GO:0008091)
0.0 0.2 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.9 GO:0097546 ciliary base(GO:0097546)
0.0 0.1 GO:0097443 sorting endosome(GO:0097443)
0.0 0.0 GO:1990812 growth cone filopodium(GO:1990812)
0.0 1.0 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.0 0.3 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.9 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 0.2 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.3 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.2 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 1.7 GO:0044455 mitochondrial membrane part(GO:0044455)
0.0 0.2 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.1 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.3 GO:0099634 postsynaptic specialization membrane(GO:0099634)
0.0 0.1 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 2.7 GO:0043679 axon terminus(GO:0043679)
0.0 4.7 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 1.2 GO:0005811 lipid particle(GO:0005811)
0.0 0.1 GO:0097449 astrocyte projection(GO:0097449)
0.0 0.1 GO:0072687 meiotic spindle(GO:0072687)
0.0 1.4 GO:0015934 large ribosomal subunit(GO:0015934)
0.0 0.3 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.1 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.8 GO:0080130 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069) L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.6 1.7 GO:0004771 sterol esterase activity(GO:0004771) retinyl-palmitate esterase activity(GO:0050253)
0.4 1.6 GO:0004092 carnitine O-acetyltransferase activity(GO:0004092)
0.4 1.4 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733)
0.3 1.6 GO:0004111 creatine kinase activity(GO:0004111)
0.2 1.1 GO:0004359 glutaminase activity(GO:0004359)
0.2 0.5 GO:0051538 3 iron, 4 sulfur cluster binding(GO:0051538)
0.2 1.2 GO:0005499 vitamin D binding(GO:0005499)
0.2 0.5 GO:0001729 ceramide kinase activity(GO:0001729)
0.2 1.5 GO:0035473 lipase binding(GO:0035473)
0.1 1.3 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 0.4 GO:0015140 malate transmembrane transporter activity(GO:0015140)
0.1 0.4 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.1 1.1 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1 0.7 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.1 0.6 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1 0.4 GO:0016748 succinyltransferase activity(GO:0016748)
0.1 0.6 GO:0043532 angiostatin binding(GO:0043532)
0.1 1.0 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 0.5 GO:0015232 heme transporter activity(GO:0015232)
0.1 0.5 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.1 0.3 GO:0015182 L-asparagine transmembrane transporter activity(GO:0015182)
0.1 0.8 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1 0.6 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.1 0.3 GO:0035939 microsatellite binding(GO:0035939)
0.1 0.9 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 0.4 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 1.4 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 0.6 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.1 0.3 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.1 0.5 GO:0048039 ubiquinone binding(GO:0048039)
0.1 0.3 GO:0031708 endothelin B receptor binding(GO:0031708)
0.1 0.3 GO:0001847 opsonin receptor activity(GO:0001847)
0.1 1.0 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 0.2 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.1 0.3 GO:0050436 microfibril binding(GO:0050436)
0.1 0.2 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.1 0.5 GO:0015288 porin activity(GO:0015288)
0.1 0.2 GO:0004471 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.1 0.4 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.1 0.5 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.1 0.3 GO:0030621 U4 snRNA binding(GO:0030621)
0.1 1.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 0.8 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.2 GO:0002153 steroid receptor RNA activator RNA binding(GO:0002153)
0.1 0.3 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745) peptidoglycan receptor activity(GO:0016019)
0.1 0.4 GO:0033142 progesterone receptor binding(GO:0033142)
0.1 0.5 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.1 0.3 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 0.7 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.1 0.2 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.1 1.3 GO:0017081 chloride channel regulator activity(GO:0017081)
0.1 0.3 GO:0034235 GPI anchor binding(GO:0034235)
0.1 0.2 GO:0030943 mitochondrion targeting sequence binding(GO:0030943)
0.1 0.3 GO:0004925 prolactin receptor activity(GO:0004925)
0.0 1.6 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.1 GO:0004998 transferrin receptor activity(GO:0004998)
0.0 0.3 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.1 GO:0008732 threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732) serine binding(GO:0070905)
0.0 0.2 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.0 0.5 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.1 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 0.2 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.1 GO:0033699 DNA 5'-adenosine monophosphate hydrolase activity(GO:0033699)
0.0 0.7 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.1 GO:0042895 antibiotic transporter activity(GO:0042895)
0.0 0.1 GO:0034617 tetrahydrobiopterin binding(GO:0034617)
0.0 0.4 GO:0015651 quaternary ammonium group transmembrane transporter activity(GO:0015651)
0.0 0.1 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.0 0.4 GO:0090482 vitamin transmembrane transporter activity(GO:0090482)
0.0 0.2 GO:0000832 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.0 0.3 GO:0046790 virion binding(GO:0046790)
0.0 0.2 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.0 0.2 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.1 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.7 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 0.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.4 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.2 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.0 0.2 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.1 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.0 0.1 GO:0008311 double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.0 2.9 GO:0005179 hormone activity(GO:0005179)
0.0 0.1 GO:0004568 chitinase activity(GO:0004568)
0.0 0.2 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 0.2 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.2 GO:0032052 bile acid binding(GO:0032052)
0.0 0.2 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.1 GO:1904288 BAT3 complex binding(GO:1904288)
0.0 0.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.1 GO:0004782 sulfinoalanine decarboxylase activity(GO:0004782)
0.0 0.1 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.5 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.5 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.3 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.5 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.0 0.2 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 0.1 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.3 GO:0043495 protein anchor(GO:0043495)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 1.0 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.8 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 0.1 GO:0034437 glycoprotein transporter activity(GO:0034437)
0.0 0.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.4 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.4 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.2 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.2 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.1 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.1 GO:0045340 mercury ion binding(GO:0045340)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.1 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.1 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.5 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.0 GO:0016649 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.0 0.1 GO:0048185 activin binding(GO:0048185)
0.0 1.0 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.4 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.0 0.3 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.0 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.0 0.1 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 0.1 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0 0.3 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.1 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 0.1 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.0 0.4 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.2 GO:0015114 phosphate ion transmembrane transporter activity(GO:0015114)
0.0 0.0 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.2 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024) protein-hormone receptor activity(GO:0016500)
0.0 0.1 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
0.0 0.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.0 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.5 GO:0005109 frizzled binding(GO:0005109)
0.0 0.0 GO:0072541 peroxynitrite reductase activity(GO:0072541)
0.0 1.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0004064 arylesterase activity(GO:0004064)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.4 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.8 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.4 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.5 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 1.6 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.5 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.2 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.5 PID BARD1 PATHWAY BARD1 signaling events
0.0 2.5 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.3 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.1 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.4 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 0.2 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.1 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.3 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.4 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.8 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.2 3.7 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 0.1 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.1 1.3 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 1.4 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.1 1.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 0.6 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0 1.6 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 1.0 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.5 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.6 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.6 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 1.7 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 1.8 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.5 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.8 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 2.0 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.6 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.4 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.5 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.3 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.3 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.5 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.4 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.3 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.4 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.2 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.7 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.4 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 0.3 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.3 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 1.0 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.2 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.1 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.6 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.2 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.4 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.2 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.4 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis