avrg: GSE58827: Dynamics of the Mouse Liver
Gene Symbol | Gene ID | Gene Info |
---|---|---|
Sox4
|
ENSMUSG00000076431.4 | SRY (sex determining region Y)-box 4 |
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Sox4 | mm10_v2_chr13_-_28953690_28953713 | 0.71 | 1.5e-06 | Click! |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
4.5 | 13.5 | GO:0060217 | hemangioblast cell differentiation(GO:0060217) |
2.7 | 8.1 | GO:1904158 | axonemal central apparatus assembly(GO:1904158) |
2.1 | 16.9 | GO:0015671 | oxygen transport(GO:0015671) |
1.9 | 5.8 | GO:1903438 | regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490) |
1.3 | 5.2 | GO:0003365 | establishment of cell polarity involved in ameboidal cell migration(GO:0003365) |
1.2 | 3.7 | GO:1904207 | regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209) |
1.1 | 3.4 | GO:0031662 | regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) |
1.1 | 4.4 | GO:0061153 | negative regulation of interleukin-13 production(GO:0032696) trachea submucosa development(GO:0061152) trachea gland development(GO:0061153) odontoblast differentiation(GO:0071895) regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899) |
1.1 | 3.2 | GO:2000620 | positive regulation of histone H4-K16 acetylation(GO:2000620) |
1.0 | 6.0 | GO:0010747 | positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747) |
1.0 | 3.8 | GO:0031117 | positive regulation of microtubule depolymerization(GO:0031117) |
0.9 | 15.3 | GO:0061179 | negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179) |
0.8 | 16.8 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
0.8 | 7.8 | GO:0015727 | lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879) |
0.7 | 16.6 | GO:2000251 | positive regulation of actin cytoskeleton reorganization(GO:2000251) |
0.7 | 12.7 | GO:0070307 | lens fiber cell development(GO:0070307) |
0.7 | 2.1 | GO:0071707 | immunoglobulin heavy chain V-D-J recombination(GO:0071707) |
0.7 | 2.0 | GO:0060983 | epicardium-derived cardiac vascular smooth muscle cell differentiation(GO:0060983) |
0.6 | 5.5 | GO:0035542 | regulation of SNARE complex assembly(GO:0035542) |
0.6 | 6.3 | GO:0005513 | detection of calcium ion(GO:0005513) |
0.6 | 9.4 | GO:0000212 | meiotic spindle organization(GO:0000212) |
0.5 | 2.1 | GO:1904425 | negative regulation of GTP binding(GO:1904425) |
0.4 | 3.4 | GO:0018243 | protein O-linked glycosylation via threonine(GO:0018243) |
0.4 | 9.1 | GO:0050774 | negative regulation of dendrite morphogenesis(GO:0050774) |
0.4 | 1.5 | GO:1904049 | negative regulation of spontaneous neurotransmitter secretion(GO:1904049) |
0.4 | 4.2 | GO:0089711 | L-glutamate transmembrane transport(GO:0089711) |
0.4 | 1.1 | GO:0032241 | positive regulation of nucleobase-containing compound transport(GO:0032241) |
0.4 | 2.5 | GO:0045876 | positive regulation of sister chromatid cohesion(GO:0045876) |
0.3 | 1.0 | GO:0071544 | diphosphoinositol polyphosphate catabolic process(GO:0071544) |
0.3 | 4.0 | GO:0031274 | positive regulation of pseudopodium assembly(GO:0031274) |
0.3 | 8.3 | GO:0048368 | lateral mesoderm development(GO:0048368) |
0.3 | 6.8 | GO:0007614 | short-term memory(GO:0007614) |
0.3 | 4.9 | GO:0009263 | deoxyribonucleotide biosynthetic process(GO:0009263) |
0.3 | 1.1 | GO:0060709 | glycogen cell differentiation involved in embryonic placenta development(GO:0060709) |
0.3 | 1.3 | GO:0045578 | negative regulation of B cell differentiation(GO:0045578) |
0.2 | 2.9 | GO:0061302 | smooth muscle cell-matrix adhesion(GO:0061302) |
0.2 | 1.2 | GO:0070934 | CRD-mediated mRNA stabilization(GO:0070934) |
0.2 | 2.0 | GO:0097118 | neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118) |
0.2 | 1.3 | GO:0042699 | follicle-stimulating hormone signaling pathway(GO:0042699) |
0.2 | 5.4 | GO:0032012 | ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012) |
0.2 | 0.9 | GO:1902897 | regulation of postsynaptic density protein 95 clustering(GO:1902897) regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758) |
0.2 | 2.6 | GO:0014842 | regulation of skeletal muscle satellite cell proliferation(GO:0014842) |
0.2 | 1.3 | GO:1904953 | Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation(GO:1904953) |
0.1 | 0.7 | GO:0060244 | negative regulation of cell proliferation involved in contact inhibition(GO:0060244) |
0.1 | 2.1 | GO:0060965 | negative regulation of gene silencing by miRNA(GO:0060965) |
0.1 | 1.1 | GO:1903351 | response to dopamine(GO:1903350) cellular response to dopamine(GO:1903351) |
0.1 | 3.6 | GO:0032967 | positive regulation of collagen biosynthetic process(GO:0032967) |
0.1 | 9.2 | GO:0055092 | cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092) |
0.1 | 0.9 | GO:0050882 | voluntary musculoskeletal movement(GO:0050882) |
0.1 | 0.4 | GO:0019348 | dolichol metabolic process(GO:0019348) |
0.1 | 13.2 | GO:0008654 | phospholipid biosynthetic process(GO:0008654) |
0.1 | 1.7 | GO:0035855 | megakaryocyte development(GO:0035855) |
0.1 | 0.7 | GO:0060159 | regulation of dopamine receptor signaling pathway(GO:0060159) |
0.1 | 0.5 | GO:0009301 | snRNA transcription(GO:0009301) |
0.0 | 6.9 | GO:0006261 | DNA-dependent DNA replication(GO:0006261) |
0.0 | 0.9 | GO:0001886 | endothelial cell morphogenesis(GO:0001886) |
0.0 | 2.1 | GO:0034605 | cellular response to heat(GO:0034605) |
0.0 | 2.5 | GO:0070527 | platelet aggregation(GO:0070527) |
0.0 | 0.8 | GO:0021535 | cell migration in hindbrain(GO:0021535) |
0.0 | 0.5 | GO:0022027 | interkinetic nuclear migration(GO:0022027) |
0.0 | 0.3 | GO:0045721 | negative regulation of gluconeogenesis(GO:0045721) |
0.0 | 4.8 | GO:0008360 | regulation of cell shape(GO:0008360) |
0.0 | 1.1 | GO:0001825 | blastocyst formation(GO:0001825) |
0.0 | 0.6 | GO:0010842 | retina layer formation(GO:0010842) |
0.0 | 0.4 | GO:0045671 | negative regulation of osteoclast differentiation(GO:0045671) |
0.0 | 3.4 | GO:0006364 | rRNA processing(GO:0006364) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
4.5 | 13.5 | GO:0033193 | Lsd1/2 complex(GO:0033193) |
2.8 | 8.3 | GO:0071149 | TEAD-2-YAP complex(GO:0071149) |
2.1 | 16.9 | GO:0005833 | hemoglobin complex(GO:0005833) |
1.7 | 6.9 | GO:0008623 | CHRAC(GO:0008623) |
1.4 | 16.6 | GO:0071439 | clathrin complex(GO:0071439) |
1.2 | 3.6 | GO:0038045 | large latent transforming growth factor-beta complex(GO:0038045) |
1.0 | 4.9 | GO:0005971 | ribonucleoside-diphosphate reductase complex(GO:0005971) |
0.6 | 4.3 | GO:0005638 | lamin filament(GO:0005638) |
0.5 | 3.7 | GO:0033269 | internode region of axon(GO:0033269) |
0.4 | 5.8 | GO:1990023 | mitotic spindle midzone(GO:1990023) |
0.4 | 4.4 | GO:1990907 | beta-catenin-TCF complex(GO:1990907) |
0.3 | 2.5 | GO:0042382 | paraspeckles(GO:0042382) |
0.3 | 1.5 | GO:1990761 | growth cone lamellipodium(GO:1990761) |
0.3 | 14.5 | GO:0032154 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
0.2 | 1.2 | GO:0070937 | CRD-mediated mRNA stability complex(GO:0070937) |
0.1 | 1.3 | GO:1990909 | Wnt signalosome(GO:1990909) |
0.1 | 2.0 | GO:0036057 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
0.1 | 12.7 | GO:0005882 | intermediate filament(GO:0005882) |
0.1 | 9.4 | GO:0072686 | mitotic spindle(GO:0072686) |
0.1 | 5.2 | GO:0008180 | COP9 signalosome(GO:0008180) |
0.1 | 0.4 | GO:0033185 | dolichol-phosphate-mannose synthase complex(GO:0033185) |
0.1 | 2.1 | GO:0045120 | pronucleus(GO:0045120) |
0.1 | 1.1 | GO:0005686 | U2 snRNP(GO:0005686) U2-type prespliceosome(GO:0071004) |
0.1 | 5.9 | GO:0036126 | sperm flagellum(GO:0036126) |
0.1 | 6.3 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
0.1 | 5.5 | GO:0031526 | brush border membrane(GO:0031526) |
0.1 | 11.0 | GO:0005741 | mitochondrial outer membrane(GO:0005741) |
0.0 | 3.4 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
0.0 | 4.2 | GO:0005791 | rough endoplasmic reticulum(GO:0005791) |
0.0 | 6.1 | GO:0030139 | endocytic vesicle(GO:0030139) |
0.0 | 2.0 | GO:0009925 | basal plasma membrane(GO:0009925) |
0.0 | 11.8 | GO:0005743 | mitochondrial inner membrane(GO:0005743) |
0.0 | 1.1 | GO:0016592 | mediator complex(GO:0016592) |
0.0 | 0.7 | GO:0032809 | neuronal cell body membrane(GO:0032809) |
0.0 | 1.9 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
0.0 | 7.1 | GO:0000139 | Golgi membrane(GO:0000139) |
0.0 | 3.8 | GO:0030027 | lamellipodium(GO:0030027) |
0.0 | 2.9 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
0.0 | 0.8 | GO:0030672 | synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501) |
0.0 | 0.9 | GO:0043198 | dendritic shaft(GO:0043198) |
0.0 | 0.7 | GO:0005776 | autophagosome(GO:0005776) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
4.2 | 16.9 | GO:0031721 | hemoglobin alpha binding(GO:0031721) |
2.6 | 15.7 | GO:0017077 | oxidative phosphorylation uncoupler activity(GO:0017077) |
1.2 | 7.4 | GO:0047184 | 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184) |
1.1 | 16.8 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
1.0 | 5.2 | GO:0043532 | angiostatin binding(GO:0043532) |
1.0 | 4.9 | GO:0061731 | ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731) |
0.9 | 3.6 | GO:0050436 | microfibril binding(GO:0050436) |
0.8 | 5.5 | GO:0008241 | peptidyl-dipeptidase activity(GO:0008241) |
0.7 | 4.2 | GO:0000099 | sulfur amino acid transmembrane transporter activity(GO:0000099) |
0.6 | 4.4 | GO:0030284 | estrogen receptor activity(GO:0030284) |
0.6 | 12.7 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
0.4 | 1.3 | GO:0031826 | type 2A serotonin receptor binding(GO:0031826) |
0.4 | 1.2 | GO:0033680 | ATP-dependent DNA/RNA helicase activity(GO:0033680) |
0.4 | 9.2 | GO:0017128 | phospholipid scramblase activity(GO:0017128) |
0.4 | 8.3 | GO:0001134 | transcription factor activity, transcription factor recruiting(GO:0001134) |
0.3 | 2.9 | GO:0038062 | protein tyrosine kinase collagen receptor activity(GO:0038062) |
0.3 | 6.0 | GO:0102391 | decanoate--CoA ligase activity(GO:0102391) |
0.3 | 2.1 | GO:0046976 | histone methyltransferase activity (H3-K27 specific)(GO:0046976) |
0.3 | 2.0 | GO:0015129 | lactate transmembrane transporter activity(GO:0015129) |
0.3 | 5.8 | GO:0003841 | 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) |
0.3 | 2.0 | GO:0070699 | type II activin receptor binding(GO:0070699) |
0.3 | 6.3 | GO:0015269 | calcium-activated potassium channel activity(GO:0015269) |
0.2 | 13.5 | GO:0070888 | E-box binding(GO:0070888) |
0.2 | 3.7 | GO:0016493 | C-C chemokine receptor activity(GO:0016493) |
0.2 | 4.0 | GO:0017049 | GTP-Rho binding(GO:0017049) |
0.2 | 1.0 | GO:0034432 | endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) |
0.2 | 5.8 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
0.2 | 3.4 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
0.2 | 5.4 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
0.1 | 0.4 | GO:0016316 | phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) |
0.1 | 0.4 | GO:0004582 | dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582) |
0.1 | 3.4 | GO:0043274 | phospholipase binding(GO:0043274) |
0.1 | 9.4 | GO:0004197 | cysteine-type endopeptidase activity(GO:0004197) |
0.1 | 9.1 | GO:0097110 | scaffold protein binding(GO:0097110) |
0.1 | 0.9 | GO:0046790 | virion binding(GO:0046790) |
0.1 | 1.1 | GO:0030235 | nitric-oxide synthase regulator activity(GO:0030235) |
0.1 | 8.1 | GO:0051082 | unfolded protein binding(GO:0051082) |
0.1 | 2.1 | GO:0017091 | AU-rich element binding(GO:0017091) |
0.0 | 0.6 | GO:0019911 | structural constituent of myelin sheath(GO:0019911) |
0.0 | 1.1 | GO:0008143 | poly(A) binding(GO:0008143) |
0.0 | 1.5 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
0.0 | 3.8 | GO:0048306 | calcium-dependent protein binding(GO:0048306) |
0.0 | 0.9 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
0.0 | 4.2 | GO:0000980 | RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980) |
0.0 | 0.9 | GO:0005521 | lamin binding(GO:0005521) |
0.0 | 13.6 | GO:0005543 | phospholipid binding(GO:0005543) |
0.0 | 1.3 | GO:0005109 | frizzled binding(GO:0005109) |
0.0 | 4.8 | GO:0017124 | SH3 domain binding(GO:0017124) |
0.0 | 3.5 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
0.0 | 4.4 | GO:0003714 | transcription corepressor activity(GO:0003714) |
0.0 | 3.4 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
0.0 | 1.1 | GO:0001104 | RNA polymerase II transcription cofactor activity(GO:0001104) |
0.0 | 1.1 | GO:0033613 | activating transcription factor binding(GO:0033613) |
0.0 | 0.7 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
0.0 | 0.3 | GO:0005112 | Notch binding(GO:0005112) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 16.8 | ST ERK1 ERK2 MAPK PATHWAY | ERK1/ERK2 MAPK Pathway |
0.2 | 16.7 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
0.1 | 9.1 | PID RHOA PATHWAY | RhoA signaling pathway |
0.1 | 4.8 | PID ERBB1 INTERNALIZATION PATHWAY | Internalization of ErbB1 |
0.1 | 1.3 | PID NEPHRIN NEPH1 PATHWAY | Nephrin/Neph1 signaling in the kidney podocyte |
0.1 | 3.4 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
0.0 | 4.9 | PID E2F PATHWAY | E2F transcription factor network |
0.0 | 4.8 | PID CMYB PATHWAY | C-MYB transcription factor network |
0.0 | 1.3 | PID WNT CANONICAL PATHWAY | Canonical Wnt signaling pathway |
0.0 | 4.0 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 7.4 | REACTOME ACYL CHAIN REMODELLING OF PC | Genes involved in Acyl chain remodelling of PC |
0.2 | 4.9 | REACTOME G1 S SPECIFIC TRANSCRIPTION | Genes involved in G1/S-Specific Transcription |
0.2 | 6.0 | REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS | Genes involved in Synthesis of very long-chain fatty acyl-CoAs |
0.2 | 8.3 | REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION | Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression |
0.2 | 5.2 | REACTOME SIGNALING BY HIPPO | Genes involved in Signaling by Hippo |
0.2 | 6.3 | REACTOME BASIGIN INTERACTIONS | Genes involved in Basigin interactions |
0.2 | 5.8 | REACTOME SYNTHESIS OF PA | Genes involved in Synthesis of PA |
0.2 | 6.3 | REACTOME CGMP EFFECTS | Genes involved in cGMP effects |
0.1 | 11.8 | REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS | Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. |
0.1 | 4.8 | REACTOME EGFR DOWNREGULATION | Genes involved in EGFR downregulation |
0.1 | 1.1 | REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK | Genes involved in Negative regulation of the PI3K/AKT network |
0.1 | 1.0 | REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS | Genes involved in Facilitative Na+-independent glucose transporters |
0.1 | 2.0 | REACTOME NEPHRIN INTERACTIONS | Genes involved in Nephrin interactions |
0.1 | 3.4 | REACTOME O LINKED GLYCOSYLATION OF MUCINS | Genes involved in O-linked glycosylation of mucins |
0.0 | 3.4 | REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS | Genes involved in Apoptotic cleavage of cellular proteins |
0.0 | 1.3 | REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS | Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus |
0.0 | 3.4 | REACTOME PEPTIDE CHAIN ELONGATION | Genes involved in Peptide chain elongation |
0.0 | 0.4 | REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS | Genes involved in Synthesis of substrates in N-glycan biosythesis |
0.0 | 1.1 | REACTOME MRNA SPLICING MINOR PATHWAY | Genes involved in mRNA Splicing - Minor Pathway |
0.0 | 0.5 | REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER | Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter |
0.0 | 1.1 | REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |
0.0 | 1.2 | REACTOME MRNA SPLICING | Genes involved in mRNA Splicing |
0.0 | 2.1 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
0.0 | 0.4 | REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE | Genes involved in Synthesis of PIPs at the plasma membrane |