avrg: GSE58827: Dynamics of the Mouse Liver
Gene Symbol | Gene ID | Gene Info |
---|---|---|
Creb3l2
|
ENSMUSG00000038648.5 | cAMP responsive element binding protein 3-like 2 |
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Creb3l2 | mm10_v2_chr6_-_37442095_37442154 | 0.57 | 3.0e-04 | Click! |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.0 | 5.9 | GO:0006592 | ornithine biosynthetic process(GO:0006592) |
1.7 | 8.6 | GO:0000738 | DNA catabolic process, exonucleolytic(GO:0000738) |
1.0 | 18.5 | GO:0015816 | glycine transport(GO:0015816) |
1.0 | 2.9 | GO:1903436 | regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490) |
0.7 | 3.7 | GO:2000680 | regulation of rubidium ion transport(GO:2000680) |
0.6 | 2.9 | GO:0008626 | granzyme-mediated apoptotic signaling pathway(GO:0008626) |
0.6 | 1.7 | GO:0033387 | putrescine biosynthetic process from ornithine(GO:0033387) |
0.6 | 2.8 | GO:0072429 | response to intra-S DNA damage checkpoint signaling(GO:0072429) |
0.6 | 1.7 | GO:0072573 | regulation of granuloma formation(GO:0002631) negative regulation of granuloma formation(GO:0002632) regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573) |
0.6 | 2.2 | GO:0070829 | heterochromatin maintenance(GO:0070829) |
0.4 | 1.3 | GO:1990523 | bone regeneration(GO:1990523) |
0.4 | 3.2 | GO:0051013 | microtubule severing(GO:0051013) |
0.4 | 1.6 | GO:0071431 | tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431) |
0.4 | 1.5 | GO:0006561 | proline biosynthetic process(GO:0006561) |
0.4 | 2.2 | GO:0009099 | branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099) |
0.3 | 1.3 | GO:0060800 | regulation of cell differentiation involved in embryonic placenta development(GO:0060800) |
0.3 | 1.8 | GO:1902287 | trigeminal nerve morphogenesis(GO:0021636) trigeminal nerve structural organization(GO:0021637) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287) |
0.3 | 0.8 | GO:0072717 | cellular response to actinomycin D(GO:0072717) |
0.3 | 9.8 | GO:1902175 | regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902175) |
0.2 | 1.9 | GO:1990253 | cellular response to leucine starvation(GO:1990253) |
0.2 | 1.5 | GO:0019856 | 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856) |
0.2 | 1.0 | GO:0022007 | neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007) |
0.2 | 2.0 | GO:0070245 | positive regulation of thymocyte apoptotic process(GO:0070245) |
0.1 | 4.3 | GO:0000413 | protein peptidyl-prolyl isomerization(GO:0000413) |
0.1 | 0.4 | GO:0032241 | positive regulation of nucleobase-containing compound transport(GO:0032241) |
0.1 | 1.5 | GO:0051683 | establishment of Golgi localization(GO:0051683) |
0.1 | 2.6 | GO:0046653 | tetrahydrofolate metabolic process(GO:0046653) |
0.1 | 0.9 | GO:0006621 | protein retention in ER lumen(GO:0006621) |
0.1 | 0.7 | GO:0016078 | tRNA catabolic process(GO:0016078) |
0.1 | 1.2 | GO:0010739 | positive regulation of protein kinase A signaling(GO:0010739) |
0.1 | 2.7 | GO:0006817 | phosphate ion transport(GO:0006817) |
0.1 | 2.5 | GO:0015804 | neutral amino acid transport(GO:0015804) |
0.1 | 2.5 | GO:0009251 | glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247) |
0.1 | 0.5 | GO:0035879 | lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879) |
0.1 | 0.9 | GO:0014029 | neural crest formation(GO:0014029) |
0.1 | 0.8 | GO:0034498 | early endosome to Golgi transport(GO:0034498) |
0.1 | 2.6 | GO:0000154 | rRNA modification(GO:0000154) |
0.1 | 1.0 | GO:0033234 | negative regulation of protein sumoylation(GO:0033234) |
0.1 | 1.5 | GO:0007095 | mitotic G2 DNA damage checkpoint(GO:0007095) |
0.1 | 1.8 | GO:0043496 | regulation of protein homodimerization activity(GO:0043496) |
0.1 | 6.0 | GO:0035914 | skeletal muscle cell differentiation(GO:0035914) |
0.1 | 0.2 | GO:0090204 | protein localization to nuclear pore(GO:0090204) |
0.1 | 0.8 | GO:0060693 | regulation of branching involved in salivary gland morphogenesis(GO:0060693) |
0.1 | 0.8 | GO:0060575 | intestinal epithelial cell differentiation(GO:0060575) |
0.1 | 1.9 | GO:0006383 | transcription from RNA polymerase III promoter(GO:0006383) |
0.1 | 0.7 | GO:0045899 | positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899) |
0.1 | 8.5 | GO:0007050 | cell cycle arrest(GO:0007050) |
0.0 | 2.1 | GO:0035196 | production of miRNAs involved in gene silencing by miRNA(GO:0035196) |
0.0 | 0.5 | GO:1902231 | positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231) |
0.0 | 1.3 | GO:0033622 | integrin activation(GO:0033622) positive regulation of focal adhesion assembly(GO:0051894) |
0.0 | 0.1 | GO:0043988 | histone H3-S28 phosphorylation(GO:0043988) |
0.0 | 0.3 | GO:2000672 | negative regulation of motor neuron apoptotic process(GO:2000672) |
0.0 | 1.2 | GO:0061014 | positive regulation of mRNA catabolic process(GO:0061014) |
0.0 | 0.5 | GO:0060510 | Type II pneumocyte differentiation(GO:0060510) |
0.0 | 0.3 | GO:0035414 | negative regulation of catenin import into nucleus(GO:0035414) |
0.0 | 1.6 | GO:0006414 | translational elongation(GO:0006414) |
0.0 | 0.3 | GO:0014842 | skeletal muscle satellite cell proliferation(GO:0014841) regulation of skeletal muscle satellite cell proliferation(GO:0014842) |
0.0 | 0.4 | GO:0097034 | mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034) |
0.0 | 0.8 | GO:0006336 | DNA replication-independent nucleosome assembly(GO:0006336) |
0.0 | 0.1 | GO:0006041 | glucosamine metabolic process(GO:0006041) |
0.0 | 4.1 | GO:0042787 | protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787) |
0.0 | 0.7 | GO:0048255 | mRNA stabilization(GO:0048255) |
0.0 | 0.1 | GO:0072015 | IMP salvage(GO:0032264) glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310) |
0.0 | 0.4 | GO:0035020 | regulation of Rac protein signal transduction(GO:0035020) |
0.0 | 0.6 | GO:1903146 | regulation of mitophagy(GO:1903146) |
0.0 | 0.1 | GO:0071638 | negative regulation of T-helper 2 cell differentiation(GO:0045629) negative regulation of monocyte chemotactic protein-1 production(GO:0071638) |
0.0 | 0.4 | GO:0001921 | positive regulation of receptor recycling(GO:0001921) |
0.0 | 0.8 | GO:0005978 | glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250) |
0.0 | 0.7 | GO:0030512 | negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) |
0.0 | 0.9 | GO:0048024 | regulation of mRNA splicing, via spliceosome(GO:0048024) |
0.0 | 0.2 | GO:0032292 | myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.9 | 3.7 | GO:0097487 | multivesicular body, internal vesicle(GO:0097487) |
0.6 | 2.9 | GO:0044194 | cytolytic granule(GO:0044194) |
0.6 | 2.8 | GO:0048476 | Holliday junction resolvase complex(GO:0048476) |
0.4 | 1.9 | GO:1990131 | Gtr1-Gtr2 GTPase complex(GO:1990131) |
0.4 | 2.6 | GO:0031428 | box C/D snoRNP complex(GO:0031428) |
0.3 | 1.6 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
0.3 | 0.8 | GO:0030905 | retromer, tubulation complex(GO:0030905) |
0.2 | 2.9 | GO:1990023 | mitotic spindle midzone(GO:1990023) |
0.2 | 8.6 | GO:0015030 | Cajal body(GO:0015030) |
0.1 | 1.5 | GO:0043240 | Fanconi anaemia nuclear complex(GO:0043240) |
0.1 | 0.7 | GO:0000172 | ribonuclease MRP complex(GO:0000172) |
0.1 | 1.5 | GO:0030126 | COPI vesicle coat(GO:0030126) |
0.1 | 1.2 | GO:0000177 | cytoplasmic exosome (RNase complex)(GO:0000177) |
0.1 | 1.9 | GO:0005666 | DNA-directed RNA polymerase III complex(GO:0005666) |
0.1 | 0.5 | GO:0030896 | checkpoint clamp complex(GO:0030896) |
0.1 | 1.3 | GO:0031527 | filopodium membrane(GO:0031527) |
0.0 | 2.1 | GO:0016592 | mediator complex(GO:0016592) |
0.0 | 2.6 | GO:0030672 | synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501) |
0.0 | 0.5 | GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671) |
0.0 | 0.3 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
0.0 | 0.2 | GO:0032541 | cortical endoplasmic reticulum(GO:0032541) |
0.0 | 1.0 | GO:0016235 | aggresome(GO:0016235) |
0.0 | 0.4 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
0.0 | 0.3 | GO:0035102 | PRC1 complex(GO:0035102) |
0.0 | 1.3 | GO:0005581 | collagen trimer(GO:0005581) |
0.0 | 1.5 | GO:0016363 | nuclear matrix(GO:0016363) |
0.0 | 1.3 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.1 | 8.6 | GO:0008859 | exoribonuclease II activity(GO:0008859) |
2.0 | 5.9 | GO:0004349 | glutamate 5-kinase activity(GO:0004349) glutamate-5-semialdehyde dehydrogenase activity(GO:0004350) delta1-pyrroline-5-carboxylate synthetase activity(GO:0017084) amino acid kinase activity(GO:0019202) |
1.3 | 18.5 | GO:0015187 | glycine transmembrane transporter activity(GO:0015187) |
0.9 | 2.7 | GO:0015319 | sodium:inorganic phosphate symporter activity(GO:0015319) |
0.9 | 2.6 | GO:0004487 | methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487) |
0.8 | 9.0 | GO:0031545 | peptidyl-proline 4-dioxygenase activity(GO:0031545) |
0.7 | 2.2 | GO:0004489 | methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489) |
0.6 | 2.5 | GO:0008184 | glycogen phosphorylase activity(GO:0008184) |
0.5 | 1.5 | GO:0004087 | carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088) |
0.4 | 1.5 | GO:0004735 | pyrroline-5-carboxylate reductase activity(GO:0004735) |
0.4 | 2.2 | GO:0052656 | branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656) |
0.4 | 2.8 | GO:0008821 | crossover junction endodeoxyribonuclease activity(GO:0008821) |
0.3 | 0.9 | GO:0001042 | RNA polymerase I core binding(GO:0001042) |
0.3 | 1.1 | GO:0004096 | catalase activity(GO:0004096) |
0.3 | 1.3 | GO:0005250 | A-type (transient outward) potassium channel activity(GO:0005250) |
0.2 | 2.1 | GO:0043023 | ribosomal large subunit binding(GO:0043023) |
0.2 | 0.7 | GO:0000171 | ribonuclease MRP activity(GO:0000171) |
0.2 | 0.9 | GO:0046923 | ER retention sequence binding(GO:0046923) |
0.2 | 1.7 | GO:0061578 | Lys63-specific deubiquitinase activity(GO:0061578) |
0.2 | 4.2 | GO:0005528 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
0.2 | 0.8 | GO:1990460 | leptin receptor binding(GO:1990460) |
0.2 | 2.6 | GO:1990226 | histone methyltransferase binding(GO:1990226) |
0.2 | 2.2 | GO:1990825 | sequence-specific mRNA binding(GO:1990825) |
0.1 | 1.8 | GO:0017154 | semaphorin receptor activity(GO:0017154) |
0.1 | 0.5 | GO:0008853 | exodeoxyribonuclease III activity(GO:0008853) |
0.1 | 0.8 | GO:0070180 | large ribosomal subunit rRNA binding(GO:0070180) |
0.1 | 1.9 | GO:0001056 | RNA polymerase III activity(GO:0001056) |
0.1 | 2.9 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
0.1 | 0.8 | GO:0035251 | UDP-glucosyltransferase activity(GO:0035251) |
0.1 | 5.5 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
0.1 | 0.5 | GO:0015129 | lactate transmembrane transporter activity(GO:0015129) |
0.1 | 1.6 | GO:0003746 | translation elongation factor activity(GO:0003746) |
0.1 | 2.5 | GO:0015175 | neutral amino acid transmembrane transporter activity(GO:0015175) |
0.1 | 1.2 | GO:0008179 | adenylate cyclase binding(GO:0008179) |
0.1 | 1.3 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
0.1 | 1.5 | GO:0070182 | DNA polymerase binding(GO:0070182) |
0.0 | 2.0 | GO:0051059 | NF-kappaB binding(GO:0051059) |
0.0 | 1.4 | GO:0005520 | insulin-like growth factor binding(GO:0005520) |
0.0 | 1.7 | GO:0016831 | carboxy-lyase activity(GO:0016831) |
0.0 | 1.2 | GO:0017025 | TBP-class protein binding(GO:0017025) |
0.0 | 1.0 | GO:0019789 | SUMO transferase activity(GO:0019789) |
0.0 | 3.9 | GO:0001104 | RNA polymerase II transcription cofactor activity(GO:0001104) |
0.0 | 0.3 | GO:0070097 | delta-catenin binding(GO:0070097) |
0.0 | 0.4 | GO:0043008 | ATP-dependent protein binding(GO:0043008) |
0.0 | 0.1 | GO:0004449 | isocitrate dehydrogenase (NAD+) activity(GO:0004449) |
0.0 | 0.4 | GO:0008266 | poly(U) RNA binding(GO:0008266) |
0.0 | 0.5 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
0.0 | 0.1 | GO:0003876 | AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623) |
0.0 | 0.7 | GO:0045182 | translation regulator activity(GO:0045182) |
0.0 | 9.7 | GO:0005509 | calcium ion binding(GO:0005509) |
0.0 | 0.5 | GO:0016504 | peptidase activator activity(GO:0016504) |
0.0 | 1.0 | GO:0048365 | Rac GTPase binding(GO:0048365) |
0.0 | 1.3 | GO:0005178 | integrin binding(GO:0005178) |
0.0 | 0.3 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
0.0 | 1.1 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 2.9 | SA CASPASE CASCADE | Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade. |
0.1 | 6.8 | PID ERA GENOMIC PATHWAY | Validated nuclear estrogen receptor alpha network |
0.1 | 1.0 | ST JAK STAT PATHWAY | Jak-STAT Pathway |
0.1 | 7.3 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
0.1 | 1.0 | PID BARD1 PATHWAY | BARD1 signaling events |
0.1 | 1.7 | ST TUMOR NECROSIS FACTOR PATHWAY | Tumor Necrosis Factor Pathway. |
0.0 | 1.0 | PID BETA CATENIN DEG PATHWAY | Degradation of beta catenin |
0.0 | 2.0 | PID FANCONI PATHWAY | Fanconi anemia pathway |
0.0 | 1.3 | PID WNT SIGNALING PATHWAY | Wnt signaling network |
0.0 | 1.3 | NABA COLLAGENS | Genes encoding collagen proteins |
0.0 | 0.8 | PID THROMBIN PAR1 PATHWAY | PAR1-mediated thrombin signaling events |
0.0 | 0.8 | PID P53 REGULATION PATHWAY | p53 pathway |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 21.0 | REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
0.3 | 7.3 | REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION | Genes involved in Amino acid synthesis and interconversion (transamination) |
0.1 | 8.6 | REACTOME INTERFERON ALPHA BETA SIGNALING | Genes involved in Interferon alpha/beta signaling |
0.1 | 3.5 | REACTOME RNA POL III TRANSCRIPTION TERMINATION | Genes involved in RNA Polymerase III Transcription Termination |
0.1 | 2.5 | REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS | Genes involved in Glycogen breakdown (glycogenolysis) |
0.1 | 1.8 | REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION | Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion |
0.1 | 2.4 | REACTOME AMINE COMPOUND SLC TRANSPORTERS | Genes involved in Amine compound SLC transporters |
0.1 | 1.2 | REACTOME METABOLISM OF POLYAMINES | Genes involved in Metabolism of polyamines |
0.1 | 2.3 | REACTOME SIGNALING BY HIPPO | Genes involved in Signaling by Hippo |
0.1 | 2.9 | REACTOME INTRINSIC PATHWAY FOR APOPTOSIS | Genes involved in Intrinsic Pathway for Apoptosis |
0.1 | 2.5 | REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
0.0 | 1.5 | REACTOME PYRIMIDINE METABOLISM | Genes involved in Pyrimidine metabolism |
0.0 | 1.7 | REACTOME NOD1 2 SIGNALING PATHWAY | Genes involved in NOD1/2 Signaling Pathway |
0.0 | 3.7 | REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | Genes involved in Response to elevated platelet cytosolic Ca2+ |
0.0 | 0.5 | REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
0.0 | 2.7 | REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
0.0 | 1.5 | REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S | Genes involved in Activation of Chaperone Genes by XBP1(S) |
0.0 | 2.2 | REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |
0.0 | 0.4 | REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS | Genes involved in Trafficking of GluR2-containing AMPA receptors |
0.0 | 1.2 | REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
0.0 | 0.7 | REACTOME MRNA 3 END PROCESSING | Genes involved in mRNA 3'-end processing |
0.0 | 0.5 | REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS | Genes involved in Activation of ATR in response to replication stress |
0.0 | 1.3 | REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
0.0 | 0.8 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
0.0 | 2.0 | REACTOME TRANSLATION | Genes involved in Translation |