avrg: GSE58827: Dynamics of the Mouse Liver
Gene Symbol | Gene ID | Gene Info |
---|---|---|
Hnf1b
|
ENSMUSG00000020679.5 | HNF1 homeobox B |
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Hnf1b | mm10_v2_chr11_+_83850832_83850855 | 0.07 | 6.9e-01 | Click! |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
5.6 | 66.8 | GO:0052697 | flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697) |
5.6 | 27.8 | GO:0052695 | cellular glucuronidation(GO:0052695) |
5.5 | 5.5 | GO:0050787 | detoxification of mercury ion(GO:0050787) |
4.4 | 13.1 | GO:0034395 | regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395) |
4.2 | 16.7 | GO:0009441 | glycolate metabolic process(GO:0009441) |
3.4 | 10.3 | GO:1902569 | regulation of activation of JAK2 kinase activity(GO:0010534) activation of JAK2 kinase activity(GO:0042977) negative regulation of activation of JAK2 kinase activity(GO:1902569) |
3.4 | 10.3 | GO:0010716 | negative regulation of extracellular matrix disassembly(GO:0010716) |
3.2 | 19.1 | GO:0038161 | prolactin signaling pathway(GO:0038161) |
3.2 | 9.5 | GO:0009812 | flavonoid metabolic process(GO:0009812) |
2.8 | 16.8 | GO:0015712 | hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760) |
2.7 | 8.0 | GO:0051659 | maintenance of mitochondrion location(GO:0051659) |
2.5 | 17.7 | GO:0015842 | aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) |
2.5 | 10.0 | GO:0032379 | positive regulation of intracellular lipid transport(GO:0032379) positive regulation of intracellular sterol transport(GO:0032382) positive regulation of intracellular cholesterol transport(GO:0032385) lipid hydroperoxide transport(GO:1901373) |
2.3 | 6.9 | GO:1903903 | regulation of establishment of T cell polarity(GO:1903903) |
2.3 | 6.9 | GO:0034971 | histone H3-R17 methylation(GO:0034971) |
2.1 | 12.6 | GO:0006083 | acetate metabolic process(GO:0006083) |
2.0 | 9.8 | GO:0000103 | sulfate assimilation(GO:0000103) |
1.9 | 9.6 | GO:1904721 | regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721) |
1.8 | 9.1 | GO:0051919 | positive regulation of fibrinolysis(GO:0051919) |
1.7 | 5.0 | GO:0061144 | alveolar secondary septum development(GO:0061144) |
1.6 | 8.1 | GO:0015788 | UDP-N-acetylglucosamine transport(GO:0015788) |
1.6 | 79.9 | GO:0006958 | complement activation, classical pathway(GO:0006958) |
1.6 | 7.9 | GO:0006548 | histidine catabolic process(GO:0006548) |
1.6 | 11.0 | GO:0034197 | acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197) |
1.5 | 24.0 | GO:0046415 | urate metabolic process(GO:0046415) |
1.4 | 5.7 | GO:0015886 | heme transport(GO:0015886) |
1.4 | 5.6 | GO:0015851 | nucleobase transport(GO:0015851) pyrimidine nucleobase transport(GO:0015855) |
1.3 | 3.9 | GO:0017187 | peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214) |
1.3 | 7.6 | GO:0036112 | medium-chain fatty-acyl-CoA metabolic process(GO:0036112) |
1.2 | 23.3 | GO:0042359 | vitamin D metabolic process(GO:0042359) |
1.2 | 5.9 | GO:1904253 | positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253) |
1.2 | 5.8 | GO:0042536 | negative regulation of tumor necrosis factor biosynthetic process(GO:0042536) |
1.1 | 3.4 | GO:0060392 | negative regulation of SMAD protein import into nucleus(GO:0060392) |
1.1 | 3.3 | GO:0033686 | positive regulation of luteinizing hormone secretion(GO:0033686) |
1.1 | 8.5 | GO:0019695 | choline metabolic process(GO:0019695) |
1.0 | 24.7 | GO:0015721 | bile acid and bile salt transport(GO:0015721) |
1.0 | 6.0 | GO:0060745 | Sertoli cell proliferation(GO:0060011) prostate epithelial cord elongation(GO:0060523) mammary gland branching involved in pregnancy(GO:0060745) |
1.0 | 6.0 | GO:0043102 | amino acid salvage(GO:0043102) L-methionine salvage(GO:0071267) |
1.0 | 6.9 | GO:0009235 | cobalamin metabolic process(GO:0009235) |
1.0 | 3.9 | GO:0009436 | glyoxylate catabolic process(GO:0009436) |
0.9 | 4.6 | GO:0051005 | negative regulation of lipoprotein lipase activity(GO:0051005) |
0.9 | 4.4 | GO:0060971 | embryonic heart tube left/right pattern formation(GO:0060971) |
0.8 | 3.4 | GO:0006659 | phosphatidylserine biosynthetic process(GO:0006659) |
0.8 | 2.3 | GO:0090080 | positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080) |
0.7 | 5.0 | GO:0019532 | oxalate transport(GO:0019532) |
0.7 | 3.4 | GO:0007217 | tachykinin receptor signaling pathway(GO:0007217) |
0.7 | 12.5 | GO:0006704 | glucocorticoid biosynthetic process(GO:0006704) |
0.6 | 5.4 | GO:0035021 | negative regulation of Rac protein signal transduction(GO:0035021) |
0.6 | 1.8 | GO:0036462 | TRAIL-activated apoptotic signaling pathway(GO:0036462) |
0.6 | 4.4 | GO:0018401 | peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) |
0.5 | 4.7 | GO:0006729 | tetrahydrobiopterin biosynthetic process(GO:0006729) |
0.5 | 3.1 | GO:0016557 | peroxisome membrane biogenesis(GO:0016557) |
0.5 | 25.9 | GO:0006805 | xenobiotic metabolic process(GO:0006805) |
0.5 | 3.4 | GO:0061113 | pancreas morphogenesis(GO:0061113) |
0.5 | 0.5 | GO:0071718 | sodium-independent icosanoid transport(GO:0071718) |
0.5 | 1.8 | GO:0043152 | induction of bacterial agglutination(GO:0043152) |
0.4 | 4.9 | GO:0015868 | purine ribonucleotide transport(GO:0015868) |
0.4 | 1.3 | GO:0090081 | regulation of heart induction by regulation of canonical Wnt signaling pathway(GO:0090081) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) regulation of midbrain dopaminergic neuron differentiation(GO:1904956) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066) |
0.4 | 3.7 | GO:0042989 | sequestering of actin monomers(GO:0042989) |
0.4 | 0.8 | GO:0034443 | negative regulation of lipoprotein oxidation(GO:0034443) |
0.4 | 6.2 | GO:0010225 | response to UV-C(GO:0010225) |
0.4 | 3.7 | GO:0030050 | vesicle transport along actin filament(GO:0030050) |
0.3 | 10.3 | GO:0055090 | acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328) |
0.3 | 7.9 | GO:0006991 | response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501) |
0.3 | 3.3 | GO:0006104 | succinyl-CoA metabolic process(GO:0006104) |
0.3 | 3.2 | GO:0045198 | establishment of epithelial cell apical/basal polarity(GO:0045198) |
0.3 | 2.5 | GO:0018026 | peptidyl-lysine monomethylation(GO:0018026) |
0.3 | 0.9 | GO:0007521 | muscle cell fate determination(GO:0007521) |
0.3 | 7.6 | GO:1902043 | positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043) |
0.3 | 3.6 | GO:0061088 | sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088) |
0.3 | 0.8 | GO:0002223 | stimulatory C-type lectin receptor signaling pathway(GO:0002223) |
0.3 | 1.3 | GO:0071475 | cellular hyperosmotic salinity response(GO:0071475) |
0.3 | 1.0 | GO:1903347 | negative regulation of bicellular tight junction assembly(GO:1903347) |
0.2 | 30.8 | GO:0035725 | sodium ion transmembrane transport(GO:0035725) |
0.2 | 3.5 | GO:0036159 | inner dynein arm assembly(GO:0036159) |
0.2 | 0.5 | GO:0016332 | establishment or maintenance of polarity of embryonic epithelium(GO:0016332) |
0.2 | 2.1 | GO:2000857 | positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860) |
0.2 | 0.9 | GO:1900220 | semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220) |
0.2 | 5.5 | GO:0015813 | L-glutamate transport(GO:0015813) |
0.2 | 8.5 | GO:0051180 | vitamin transport(GO:0051180) |
0.2 | 1.5 | GO:1902260 | negative regulation of delayed rectifier potassium channel activity(GO:1902260) |
0.2 | 8.2 | GO:0032728 | positive regulation of interferon-beta production(GO:0032728) |
0.2 | 6.2 | GO:0051898 | negative regulation of protein kinase B signaling(GO:0051898) |
0.1 | 4.3 | GO:0010107 | potassium ion import(GO:0010107) |
0.1 | 0.4 | GO:0044860 | protein localization to plasma membrane raft(GO:0044860) |
0.1 | 1.7 | GO:0031468 | nuclear envelope reassembly(GO:0031468) |
0.1 | 1.0 | GO:0090400 | stress-induced premature senescence(GO:0090400) |
0.1 | 12.4 | GO:0032411 | positive regulation of transporter activity(GO:0032411) |
0.1 | 0.6 | GO:0072236 | metanephric loop of Henle development(GO:0072236) |
0.1 | 2.4 | GO:0033194 | response to hydroperoxide(GO:0033194) |
0.1 | 17.8 | GO:0098656 | anion transmembrane transport(GO:0098656) |
0.1 | 0.5 | GO:0010159 | specification of organ position(GO:0010159) |
0.1 | 1.1 | GO:0031119 | tRNA pseudouridine synthesis(GO:0031119) |
0.1 | 1.3 | GO:0035095 | behavioral response to nicotine(GO:0035095) |
0.1 | 1.2 | GO:0002862 | negative regulation of inflammatory response to antigenic stimulus(GO:0002862) |
0.1 | 1.3 | GO:0000712 | resolution of meiotic recombination intermediates(GO:0000712) |
0.1 | 1.6 | GO:0031115 | negative regulation of microtubule polymerization(GO:0031115) |
0.1 | 0.3 | GO:0018095 | protein polyglutamylation(GO:0018095) |
0.1 | 3.9 | GO:0045744 | negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744) |
0.1 | 0.4 | GO:2000234 | positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234) |
0.1 | 4.3 | GO:0046513 | ceramide biosynthetic process(GO:0046513) |
0.1 | 0.9 | GO:0090110 | cargo loading into COPII-coated vesicle(GO:0090110) |
0.1 | 1.9 | GO:0032012 | ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012) |
0.1 | 0.5 | GO:0032328 | alanine transport(GO:0032328) |
0.1 | 0.6 | GO:0030277 | maintenance of gastrointestinal epithelium(GO:0030277) |
0.1 | 21.1 | GO:0032259 | methylation(GO:0032259) |
0.0 | 4.4 | GO:0001578 | microtubule bundle formation(GO:0001578) |
0.0 | 1.3 | GO:0060065 | uterus development(GO:0060065) |
0.0 | 0.8 | GO:0045947 | negative regulation of translational initiation(GO:0045947) |
0.0 | 1.9 | GO:0070232 | regulation of T cell apoptotic process(GO:0070232) |
0.0 | 2.4 | GO:0042462 | eye photoreceptor cell development(GO:0042462) |
0.0 | 12.9 | GO:0007606 | sensory perception of chemical stimulus(GO:0007606) |
0.0 | 0.2 | GO:0044830 | modulation by host of viral RNA genome replication(GO:0044830) |
0.0 | 0.6 | GO:0030238 | male sex determination(GO:0030238) |
0.0 | 1.1 | GO:0015986 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
0.0 | 0.1 | GO:0072114 | regulation of pronephros size(GO:0035565) pronephric nephron tubule development(GO:0039020) mesonephros morphogenesis(GO:0061206) mesonephric nephron development(GO:0061215) mesonephric nephron morphogenesis(GO:0061228) mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis(GO:0061235) regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061295) negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061296) pronephros morphogenesis(GO:0072114) mesonephric duct formation(GO:0072181) mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:1901146) |
0.0 | 1.9 | GO:0007029 | endoplasmic reticulum organization(GO:0007029) |
0.0 | 3.9 | GO:0019233 | sensory perception of pain(GO:0019233) |
0.0 | 0.9 | GO:0006198 | cAMP catabolic process(GO:0006198) |
0.0 | 4.9 | GO:0035023 | regulation of Rho protein signal transduction(GO:0035023) |
0.0 | 1.7 | GO:0030032 | lamellipodium assembly(GO:0030032) |
0.0 | 3.0 | GO:0051592 | response to calcium ion(GO:0051592) |
0.0 | 0.1 | GO:0051001 | negative regulation of monooxygenase activity(GO:0032769) negative regulation of nitric-oxide synthase activity(GO:0051001) |
0.0 | 0.2 | GO:0002349 | histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553) |
0.0 | 0.0 | GO:0097274 | urea homeostasis(GO:0097274) |
0.0 | 0.1 | GO:0000957 | mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960) |
0.0 | 3.5 | GO:0006839 | mitochondrial transport(GO:0006839) |
0.0 | 2.6 | GO:0034976 | response to endoplasmic reticulum stress(GO:0034976) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
4.4 | 13.1 | GO:0032010 | phagolysosome(GO:0032010) |
2.3 | 9.1 | GO:0044279 | other organism cell membrane(GO:0044218) other organism membrane(GO:0044279) |
2.1 | 20.9 | GO:0005579 | membrane attack complex(GO:0005579) |
1.5 | 4.4 | GO:0097543 | ciliary inversin compartment(GO:0097543) |
1.4 | 5.5 | GO:0097450 | astrocyte end-foot(GO:0097450) |
1.3 | 10.3 | GO:0071438 | invadopodium membrane(GO:0071438) |
1.0 | 14.5 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
0.9 | 6.0 | GO:0097550 | transcriptional preinitiation complex(GO:0097550) |
0.8 | 10.0 | GO:0031315 | extrinsic component of mitochondrial outer membrane(GO:0031315) |
0.8 | 0.8 | GO:0034365 | discoidal high-density lipoprotein particle(GO:0034365) |
0.6 | 1.8 | GO:0030690 | Noc1p-Noc2p complex(GO:0030690) |
0.6 | 1.7 | GO:1990730 | VCP-NSFL1C complex(GO:1990730) |
0.5 | 3.3 | GO:0030062 | mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062) |
0.5 | 6.9 | GO:0001931 | uropod(GO:0001931) flotillin complex(GO:0016600) cell trailing edge(GO:0031254) |
0.5 | 5.5 | GO:0046581 | intercellular canaliculus(GO:0046581) |
0.4 | 4.3 | GO:0042627 | chylomicron(GO:0042627) |
0.3 | 8.7 | GO:0070971 | endoplasmic reticulum exit site(GO:0070971) |
0.3 | 42.1 | GO:0072562 | blood microparticle(GO:0072562) |
0.3 | 24.7 | GO:0000502 | proteasome complex(GO:0000502) |
0.2 | 2.5 | GO:0034364 | high-density lipoprotein particle(GO:0034364) |
0.2 | 4.9 | GO:0005922 | connexon complex(GO:0005922) |
0.2 | 6.9 | GO:0005719 | nuclear euchromatin(GO:0005719) |
0.2 | 15.6 | GO:0005581 | collagen trimer(GO:0005581) |
0.1 | 6.9 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
0.1 | 1.5 | GO:0000276 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) |
0.1 | 1.9 | GO:0033655 | host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655) |
0.1 | 15.1 | GO:0030176 | integral component of endoplasmic reticulum membrane(GO:0030176) |
0.1 | 4.6 | GO:0005747 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
0.1 | 2.7 | GO:0030057 | desmosome(GO:0030057) |
0.1 | 31.5 | GO:0005789 | endoplasmic reticulum membrane(GO:0005789) |
0.1 | 6.9 | GO:0005791 | rough endoplasmic reticulum(GO:0005791) |
0.1 | 17.6 | GO:0042579 | peroxisome(GO:0005777) microbody(GO:0042579) |
0.1 | 14.8 | GO:0008021 | synaptic vesicle(GO:0008021) |
0.1 | 1.0 | GO:0035631 | IkappaB kinase complex(GO:0008385) CD40 receptor complex(GO:0035631) |
0.1 | 24.4 | GO:0005743 | mitochondrial inner membrane(GO:0005743) |
0.1 | 1.3 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
0.1 | 16.1 | GO:0005759 | mitochondrial matrix(GO:0005759) |
0.1 | 1.0 | GO:0032156 | septin cytoskeleton(GO:0032156) |
0.1 | 0.4 | GO:0044352 | pinosome(GO:0044352) macropinosome(GO:0044354) |
0.1 | 9.3 | GO:0005923 | bicellular tight junction(GO:0005923) |
0.0 | 0.4 | GO:0030688 | preribosome, small subunit precursor(GO:0030688) |
0.0 | 1.9 | GO:0097610 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
0.0 | 2.5 | GO:0030667 | secretory granule membrane(GO:0030667) |
0.0 | 1.6 | GO:0044295 | axonal growth cone(GO:0044295) |
0.0 | 5.8 | GO:0031234 | extrinsic component of cytoplasmic side of plasma membrane(GO:0031234) |
0.0 | 3.3 | GO:0030864 | cortical actin cytoskeleton(GO:0030864) |
0.0 | 18.5 | GO:0005667 | transcription factor complex(GO:0005667) |
0.0 | 41.7 | GO:0005783 | endoplasmic reticulum(GO:0005783) |
0.0 | 2.4 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
0.0 | 0.9 | GO:0032809 | neuronal cell body membrane(GO:0032809) |
0.0 | 0.3 | GO:0031143 | pseudopodium(GO:0031143) |
0.0 | 5.5 | GO:0000151 | ubiquitin ligase complex(GO:0000151) |
0.0 | 6.9 | GO:0005635 | nuclear envelope(GO:0005635) |
0.0 | 0.8 | GO:0034707 | chloride channel complex(GO:0034707) |
0.0 | 1.7 | GO:0001650 | fibrillar center(GO:0001650) |
0.0 | 0.2 | GO:0031201 | SNARE complex(GO:0031201) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
7.8 | 23.3 | GO:1902271 | D3 vitamins binding(GO:1902271) |
5.6 | 16.8 | GO:0004346 | glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309) |
4.4 | 17.7 | GO:0004058 | aromatic-L-amino-acid decarboxylase activity(GO:0004058) L-dopa decarboxylase activity(GO:0036468) |
4.2 | 12.6 | GO:0019807 | aspartoacylase activity(GO:0019807) |
3.9 | 19.3 | GO:0004062 | aryl sulfotransferase activity(GO:0004062) |
3.8 | 19.1 | GO:0004925 | prolactin receptor activity(GO:0004925) |
3.8 | 11.4 | GO:0008431 | vitamin E binding(GO:0008431) |
3.7 | 47.5 | GO:0005436 | sodium:phosphate symporter activity(GO:0005436) |
3.6 | 14.5 | GO:0016899 | oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899) |
3.5 | 24.7 | GO:0008508 | bile acid:sodium symporter activity(GO:0008508) |
3.4 | 10.3 | GO:0070540 | stearic acid binding(GO:0070540) |
3.3 | 13.1 | GO:0042284 | sphingolipid delta-4 desaturase activity(GO:0042284) |
3.1 | 117.7 | GO:0015020 | glucuronosyltransferase activity(GO:0015020) |
2.5 | 10.0 | GO:0033814 | propanoyl-CoA C-acyltransferase activity(GO:0033814) propionyl-CoA C2-trimethyltridecanoyltransferase activity(GO:0050632) phosphatidylethanolamine transporter activity(GO:1904121) |
2.3 | 6.9 | GO:0038181 | bile acid receptor activity(GO:0038181) |
2.1 | 8.5 | GO:0046997 | oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997) |
2.0 | 6.0 | GO:0031798 | type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052) |
1.9 | 13.6 | GO:0005534 | galactose binding(GO:0005534) |
1.6 | 9.6 | GO:0060698 | endoribonuclease inhibitor activity(GO:0060698) |
1.4 | 5.7 | GO:0015232 | heme transporter activity(GO:0015232) |
1.1 | 5.6 | GO:0005350 | purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205) |
1.1 | 7.6 | GO:0003996 | acyl-CoA ligase activity(GO:0003996) |
1.1 | 3.3 | GO:0004774 | succinate-CoA ligase activity(GO:0004774) |
1.1 | 3.2 | GO:0003960 | NADPH:quinone reductase activity(GO:0003960) |
1.0 | 16.4 | GO:0016832 | aldehyde-lyase activity(GO:0016832) |
1.0 | 6.0 | GO:0008172 | S-methyltransferase activity(GO:0008172) |
1.0 | 22.8 | GO:0004033 | aldo-keto reductase (NADP) activity(GO:0004033) |
1.0 | 4.8 | GO:0019770 | IgG receptor activity(GO:0019770) |
0.9 | 4.7 | GO:0004505 | phenylalanine 4-monooxygenase activity(GO:0004505) |
0.9 | 10.3 | GO:0008239 | dipeptidyl-peptidase activity(GO:0008239) |
0.9 | 3.4 | GO:0004703 | G-protein coupled receptor kinase activity(GO:0004703) |
0.7 | 2.2 | GO:0036470 | tyrosine 3-monooxygenase activator activity(GO:0036470) L-dopa decarboxylase activator activity(GO:0036478) |
0.7 | 9.1 | GO:1990405 | protein antigen binding(GO:1990405) |
0.7 | 4.6 | GO:0004859 | phospholipase inhibitor activity(GO:0004859) |
0.6 | 4.3 | GO:0060230 | lipoprotein lipase activator activity(GO:0060230) |
0.6 | 12.4 | GO:0019825 | oxygen binding(GO:0019825) |
0.6 | 5.0 | GO:0005007 | fibroblast growth factor-activated receptor activity(GO:0005007) |
0.5 | 4.2 | GO:0070095 | fructose-6-phosphate binding(GO:0070095) |
0.5 | 11.8 | GO:0017081 | chloride channel regulator activity(GO:0017081) |
0.5 | 12.5 | GO:0001848 | complement binding(GO:0001848) |
0.4 | 1.3 | GO:0035827 | rubidium ion transmembrane transporter activity(GO:0035827) |
0.4 | 1.8 | GO:0035877 | death effector domain binding(GO:0035877) |
0.4 | 2.5 | GO:0008970 | phosphatidylcholine 1-acylhydrolase activity(GO:0008970) |
0.4 | 6.8 | GO:0008271 | secondary active sulfate transmembrane transporter activity(GO:0008271) |
0.3 | 8.1 | GO:0005351 | sugar:proton symporter activity(GO:0005351) |
0.3 | 3.9 | GO:0030274 | LIM domain binding(GO:0030274) |
0.3 | 1.6 | GO:0032767 | copper-dependent protein binding(GO:0032767) |
0.3 | 3.1 | GO:0000268 | peroxisome targeting sequence binding(GO:0000268) |
0.3 | 0.6 | GO:0019864 | IgG binding(GO:0019864) |
0.3 | 4.9 | GO:0005243 | gap junction channel activity(GO:0005243) |
0.3 | 5.5 | GO:0005313 | L-glutamate transmembrane transporter activity(GO:0005313) |
0.3 | 3.5 | GO:1901702 | urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702) |
0.3 | 3.3 | GO:0019911 | structural constituent of myelin sheath(GO:0019911) |
0.2 | 23.3 | GO:0008170 | N-methyltransferase activity(GO:0008170) |
0.2 | 6.2 | GO:0097602 | cullin family protein binding(GO:0097602) |
0.2 | 5.2 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
0.2 | 3.9 | GO:0048038 | quinone binding(GO:0048038) |
0.2 | 1.0 | GO:0008384 | IkappaB kinase activity(GO:0008384) |
0.2 | 0.6 | GO:0022850 | serotonin-gated cation channel activity(GO:0022850) |
0.2 | 5.1 | GO:0042165 | neurotransmitter binding(GO:0042165) |
0.2 | 7.9 | GO:0005044 | scavenger receptor activity(GO:0005044) |
0.2 | 0.8 | GO:0015111 | iodide transmembrane transporter activity(GO:0015111) |
0.2 | 10.1 | GO:0005549 | odorant binding(GO:0005549) |
0.2 | 13.1 | GO:0004869 | cysteine-type endopeptidase inhibitor activity(GO:0004869) |
0.2 | 5.9 | GO:0016709 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709) |
0.1 | 0.9 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
0.1 | 1.3 | GO:0048019 | receptor antagonist activity(GO:0048019) |
0.1 | 7.9 | GO:0016836 | hydro-lyase activity(GO:0016836) |
0.1 | 3.4 | GO:0005242 | inward rectifier potassium channel activity(GO:0005242) |
0.1 | 2.7 | GO:0045295 | gamma-catenin binding(GO:0045295) |
0.1 | 2.8 | GO:0034185 | apolipoprotein binding(GO:0034185) |
0.1 | 6.9 | GO:0035255 | ionotropic glutamate receptor binding(GO:0035255) |
0.1 | 3.3 | GO:0071855 | neuropeptide receptor binding(GO:0071855) |
0.1 | 1.2 | GO:0004602 | glutathione peroxidase activity(GO:0004602) |
0.1 | 3.6 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
0.1 | 2.4 | GO:0008137 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
0.1 | 12.8 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
0.1 | 1.0 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
0.1 | 2.3 | GO:0017134 | fibroblast growth factor binding(GO:0017134) |
0.1 | 3.7 | GO:0003785 | actin monomer binding(GO:0003785) |
0.1 | 1.9 | GO:0005537 | mannose binding(GO:0005537) |
0.1 | 6.9 | GO:0016765 | transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765) |
0.1 | 11.3 | GO:0030165 | PDZ domain binding(GO:0030165) |
0.1 | 11.7 | GO:0030414 | peptidase inhibitor activity(GO:0030414) |
0.1 | 1.5 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
0.1 | 1.1 | GO:0009982 | pseudouridine synthase activity(GO:0009982) |
0.1 | 12.2 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
0.1 | 3.5 | GO:0030331 | estrogen receptor binding(GO:0030331) |
0.1 | 0.9 | GO:0017154 | semaphorin receptor activity(GO:0017154) |
0.1 | 6.3 | GO:0003707 | steroid hormone receptor activity(GO:0003707) |
0.1 | 0.8 | GO:0000900 | translation repressor activity, nucleic acid binding(GO:0000900) |
0.1 | 1.4 | GO:0005328 | neurotransmitter:sodium symporter activity(GO:0005328) |
0.1 | 1.9 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
0.1 | 0.2 | GO:1990460 | leptin receptor binding(GO:1990460) |
0.0 | 0.6 | GO:0008301 | DNA binding, bending(GO:0008301) |
0.0 | 0.5 | GO:0004955 | prostaglandin receptor activity(GO:0004955) |
0.0 | 5.1 | GO:0042626 | ATPase activity, coupled to transmembrane movement of substances(GO:0042626) |
0.0 | 0.4 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
0.0 | 0.3 | GO:0070739 | protein-glutamic acid ligase activity(GO:0070739) |
0.0 | 2.1 | GO:0005518 | collagen binding(GO:0005518) |
0.0 | 0.9 | GO:0004115 | 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) |
0.0 | 0.4 | GO:0005149 | interleukin-1 receptor binding(GO:0005149) |
0.0 | 4.9 | GO:0005516 | calmodulin binding(GO:0005516) |
0.0 | 4.6 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
0.0 | 1.7 | GO:0019888 | protein phosphatase regulator activity(GO:0019888) |
0.0 | 5.5 | GO:0005096 | GTPase activator activity(GO:0005096) |
0.0 | 3.5 | GO:0030246 | carbohydrate binding(GO:0030246) |
0.0 | 0.5 | GO:0071837 | HMG box domain binding(GO:0071837) |
0.0 | 0.3 | GO:0042974 | retinoic acid receptor binding(GO:0042974) |
0.0 | 0.8 | GO:0016209 | antioxidant activity(GO:0016209) |
0.0 | 0.9 | GO:0048306 | calcium-dependent protein binding(GO:0048306) |
0.0 | 1.8 | GO:0001085 | RNA polymerase II transcription factor binding(GO:0001085) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 19.1 | PID ERBB4 PATHWAY | ErbB4 signaling events |
0.2 | 9.1 | PID SYNDECAN 4 PATHWAY | Syndecan-4-mediated signaling events |
0.2 | 15.7 | PID FOXO PATHWAY | FoxO family signaling |
0.2 | 4.4 | PID HIF1A PATHWAY | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha |
0.2 | 8.1 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
0.2 | 1.8 | SA FAS SIGNALING | The TNF-type receptor Fas induces apoptosis on ligand binding. |
0.1 | 6.0 | PID FOXM1 PATHWAY | FOXM1 transcription factor network |
0.1 | 6.9 | PID RXR VDR PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
0.1 | 5.6 | PID ALPHA SYNUCLEIN PATHWAY | Alpha-synuclein signaling |
0.1 | 5.2 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
0.1 | 7.2 | PID FGF PATHWAY | FGF signaling pathway |
0.1 | 5.8 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
0.1 | 10.3 | PID SMAD2 3NUCLEAR PATHWAY | Regulation of nuclear SMAD2/3 signaling |
0.1 | 7.9 | PID RHOA REG PATHWAY | Regulation of RhoA activity |
0.1 | 17.7 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
0.1 | 3.8 | PID ECADHERIN STABILIZATION PATHWAY | Stabilization and expansion of the E-cadherin adherens junction |
0.1 | 4.6 | PID AVB3 INTEGRIN PATHWAY | Integrins in angiogenesis |
0.1 | 1.8 | PID EPHRINB REV PATHWAY | Ephrin B reverse signaling |
0.1 | 12.7 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
0.1 | 1.3 | PID HDAC CLASSIII PATHWAY | Signaling events mediated by HDAC Class III |
0.0 | 1.3 | PID PS1 PATHWAY | Presenilin action in Notch and Wnt signaling |
0.0 | 1.0 | SIG CD40PATHWAYMAP | Genes related to CD40 signaling |
0.0 | 1.4 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
0.0 | 0.6 | PID AR TF PATHWAY | Regulation of Androgen receptor activity |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
3.6 | 32.7 | REACTOME RECYCLING OF BILE ACIDS AND SALTS | Genes involved in Recycling of bile acids and salts |
3.2 | 41.8 | REACTOME GLUCURONIDATION | Genes involved in Glucuronidation |
1.7 | 13.6 | REACTOME CREATION OF C4 AND C2 ACTIVATORS | Genes involved in Creation of C4 and C2 activators |
1.4 | 18.4 | REACTOME ENDOGENOUS STEROLS | Genes involved in Endogenous sterols |
1.3 | 18.8 | REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
1.0 | 19.1 | REACTOME PROLACTIN RECEPTOR SIGNALING | Genes involved in Prolactin receptor signaling |
0.9 | 23.5 | REACTOME COMPLEMENT CASCADE | Genes involved in Complement cascade |
0.9 | 17.7 | REACTOME AMINE DERIVED HORMONES | Genes involved in Amine-derived hormones |
0.8 | 23.3 | REACTOME STEROID HORMONES | Genes involved in Steroid hormones |
0.7 | 9.5 | REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES | Genes involved in Cytosolic sulfonation of small molecules |
0.7 | 10.0 | REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL | Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol |
0.5 | 10.3 | REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP | Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) |
0.4 | 3.9 | REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS | Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins |
0.4 | 21.0 | REACTOME GLUCOSE TRANSPORT | Genes involved in Glucose transport |
0.4 | 10.3 | REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS | Genes involved in Regulation of gene expression in beta cells |
0.4 | 20.8 | REACTOME PHASE II CONJUGATION | Genes involved in Phase II conjugation |
0.3 | 3.5 | REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS | Genes involved in Facilitative Na+-independent glucose transporters |
0.3 | 9.1 | REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX | Genes involved in Degradation of the extracellular matrix |
0.3 | 7.8 | REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
0.3 | 5.0 | REACTOME FGFR4 LIGAND BINDING AND ACTIVATION | Genes involved in FGFR4 ligand binding and activation |
0.2 | 4.9 | REACTOME GAP JUNCTION ASSEMBLY | Genes involved in Gap junction assembly |
0.2 | 3.5 | REACTOME REGULATION OF BETA CELL DEVELOPMENT | Genes involved in Regulation of beta-cell development |
0.2 | 4.4 | REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA | Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha |
0.2 | 8.6 | REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT | Genes involved in ABC-family proteins mediated transport |
0.2 | 8.1 | REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES | Genes involved in Transport of vitamins, nucleosides, and related molecules |
0.2 | 1.8 | REACTOME COMMON PATHWAY | Genes involved in Common Pathway |
0.2 | 6.0 | REACTOME NUCLEAR SIGNALING BY ERBB4 | Genes involved in Nuclear signaling by ERBB4 |
0.2 | 2.8 | REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 | Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 |
0.2 | 2.3 | REACTOME FGFR LIGAND BINDING AND ACTIVATION | Genes involved in FGFR ligand binding and activation |
0.1 | 3.3 | REACTOME CITRIC ACID CYCLE TCA CYCLE | Genes involved in Citric acid cycle (TCA cycle) |
0.1 | 27.1 | REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES | Genes involved in Metabolism of amino acids and derivatives |
0.1 | 12.0 | REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | Genes involved in Response to elevated platelet cytosolic Ca2+ |
0.1 | 1.4 | REACTOME PASSIVE TRANSPORT BY AQUAPORINS | Genes involved in Passive Transport by Aquaporins |
0.1 | 7.5 | REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS | Genes involved in Amino acid and oligopeptide SLC transporters |
0.1 | 5.3 | REACTOME IRON UPTAKE AND TRANSPORT | Genes involved in Iron uptake and transport |
0.1 | 6.3 | REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
0.1 | 1.3 | REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS | Genes involved in Presynaptic nicotinic acetylcholine receptors |
0.1 | 4.3 | REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS | Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits |
0.1 | 1.7 | REACTOME DCC MEDIATED ATTRACTIVE SIGNALING | Genes involved in DCC mediated attractive signaling |
0.1 | 2.7 | REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION | Genes involved in Transport to the Golgi and subsequent modification |
0.0 | 6.7 | REACTOME G ALPHA Q SIGNALLING EVENTS | Genes involved in G alpha (q) signalling events |
0.0 | 0.9 | REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |
0.0 | 5.4 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
0.0 | 3.4 | REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS | Genes involved in Glycerophospholipid biosynthesis |
0.0 | 0.6 | REACTOME LIGAND GATED ION CHANNEL TRANSPORT | Genes involved in Ligand-gated ion channel transport |
0.0 | 0.8 | REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |