avrg: GSE58827: Dynamics of the Mouse Liver
Gene Symbol | Gene ID | Gene Info |
---|---|---|
Pgr
|
ENSMUSG00000031870.10 | progesterone receptor |
Nr3c1
|
ENSMUSG00000024431.8 | nuclear receptor subfamily 3, group C, member 1 |
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Pgr | mm10_v2_chr9_+_8900459_8900489 | -0.47 | 4.1e-03 | Click! |
Nr3c1 | mm10_v2_chr18_-_39489880_39489915 | -0.24 | 1.5e-01 | Click! |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
3.5 | 13.9 | GO:0034760 | negative regulation of iron ion transport(GO:0034757) negative regulation of iron ion transmembrane transport(GO:0034760) |
0.9 | 3.7 | GO:1903033 | regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033) |
0.8 | 2.4 | GO:0006507 | GPI anchor release(GO:0006507) |
0.6 | 1.7 | GO:2000041 | regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041) |
0.5 | 5.4 | GO:0006569 | tryptophan catabolic process(GO:0006569) tryptophan catabolic process to kynurenine(GO:0019441) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218) kynurenine metabolic process(GO:0070189) |
0.4 | 1.3 | GO:0072034 | intrahepatic bile duct development(GO:0035622) renal vesicle induction(GO:0072034) |
0.3 | 3.5 | GO:0005513 | detection of calcium ion(GO:0005513) |
0.3 | 3.3 | GO:0015868 | purine ribonucleotide transport(GO:0015868) |
0.3 | 1.1 | GO:0043376 | regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376) |
0.3 | 1.1 | GO:1903422 | negative regulation of synaptic vesicle recycling(GO:1903422) |
0.3 | 13.1 | GO:0050891 | multicellular organismal water homeostasis(GO:0050891) |
0.3 | 0.8 | GO:0030908 | intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908) |
0.3 | 1.5 | GO:0015889 | cobalamin transport(GO:0015889) |
0.2 | 1.7 | GO:0015670 | carbon dioxide transport(GO:0015670) |
0.2 | 1.1 | GO:1901843 | positive regulation of high voltage-gated calcium channel activity(GO:1901843) |
0.2 | 0.4 | GO:0003169 | coronary vein morphogenesis(GO:0003169) |
0.2 | 2.1 | GO:0060355 | positive regulation of cell adhesion molecule production(GO:0060355) |
0.2 | 1.2 | GO:0003219 | cardiac right ventricle formation(GO:0003219) |
0.2 | 1.4 | GO:0061084 | negative regulation of protein refolding(GO:0061084) |
0.2 | 1.2 | GO:0030422 | production of siRNA involved in RNA interference(GO:0030422) |
0.2 | 1.3 | GO:0070327 | thyroid hormone transport(GO:0070327) |
0.2 | 0.5 | GO:0010446 | response to alkaline pH(GO:0010446) |
0.2 | 1.5 | GO:0016554 | cytidine to uridine editing(GO:0016554) |
0.1 | 1.1 | GO:0016560 | protein import into peroxisome matrix, docking(GO:0016560) |
0.1 | 0.9 | GO:0070562 | regulation of vitamin D receptor signaling pathway(GO:0070562) |
0.1 | 0.4 | GO:0051466 | corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) positive regulation of corticotropin-releasing hormone secretion(GO:0051466) |
0.1 | 0.5 | GO:0046684 | response to pyrethroid(GO:0046684) |
0.1 | 0.5 | GO:0035063 | nuclear speck organization(GO:0035063) |
0.1 | 0.6 | GO:0000429 | carbon catabolite regulation of transcription from RNA polymerase II promoter(GO:0000429) carbon catabolite activation of transcription from RNA polymerase II promoter(GO:0000436) carbon catabolite activation of transcription(GO:0045991) |
0.1 | 0.3 | GO:1990764 | regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764) |
0.1 | 0.4 | GO:0035483 | gastric emptying(GO:0035483) |
0.1 | 0.2 | GO:2000729 | positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729) |
0.1 | 0.2 | GO:0042414 | epinephrine metabolic process(GO:0042414) |
0.1 | 3.5 | GO:0032728 | positive regulation of interferon-beta production(GO:0032728) |
0.1 | 1.8 | GO:0051044 | positive regulation of membrane protein ectodomain proteolysis(GO:0051044) |
0.1 | 0.6 | GO:0048743 | positive regulation of skeletal muscle fiber development(GO:0048743) |
0.1 | 0.3 | GO:2000383 | regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384) |
0.1 | 1.2 | GO:0015937 | coenzyme A biosynthetic process(GO:0015937) |
0.1 | 0.2 | GO:0019858 | cytosine metabolic process(GO:0019858) |
0.1 | 0.8 | GO:0031468 | nuclear envelope reassembly(GO:0031468) |
0.1 | 1.5 | GO:0034453 | microtubule anchoring(GO:0034453) |
0.1 | 0.3 | GO:0090168 | Golgi reassembly(GO:0090168) |
0.1 | 0.3 | GO:0072053 | renal inner medulla development(GO:0072053) |
0.1 | 1.3 | GO:0033169 | histone H3-K9 demethylation(GO:0033169) |
0.1 | 1.4 | GO:1902043 | positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043) |
0.1 | 0.3 | GO:0048496 | maintenance of organ identity(GO:0048496) |
0.0 | 0.8 | GO:0042407 | cristae formation(GO:0042407) |
0.0 | 0.6 | GO:0048280 | vesicle fusion with Golgi apparatus(GO:0048280) |
0.0 | 2.0 | GO:0051642 | centrosome localization(GO:0051642) |
0.0 | 0.3 | GO:0021615 | glossopharyngeal nerve morphogenesis(GO:0021615) |
0.0 | 0.3 | GO:0003406 | retinal pigment epithelium development(GO:0003406) |
0.0 | 2.5 | GO:0006956 | complement activation(GO:0006956) |
0.0 | 0.6 | GO:0010155 | regulation of proton transport(GO:0010155) |
0.0 | 0.2 | GO:0038018 | Wnt receptor catabolic process(GO:0038018) |
0.0 | 1.0 | GO:0018345 | protein palmitoylation(GO:0018345) |
0.0 | 1.0 | GO:0010667 | negative regulation of cardiac muscle cell apoptotic process(GO:0010667) |
0.0 | 1.9 | GO:0042775 | mitochondrial ATP synthesis coupled electron transport(GO:0042775) |
0.0 | 0.5 | GO:0032515 | negative regulation of phosphoprotein phosphatase activity(GO:0032515) |
0.0 | 0.4 | GO:0048664 | neuron fate determination(GO:0048664) |
0.0 | 0.5 | GO:0048172 | regulation of short-term neuronal synaptic plasticity(GO:0048172) |
0.0 | 1.1 | GO:0007339 | binding of sperm to zona pellucida(GO:0007339) |
0.0 | 0.9 | GO:1903963 | arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963) |
0.0 | 0.0 | GO:0071288 | cellular response to mercury ion(GO:0071288) |
0.0 | 0.4 | GO:0045647 | negative regulation of erythrocyte differentiation(GO:0045647) |
0.0 | 0.4 | GO:0033141 | positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141) |
0.0 | 0.6 | GO:0001945 | lymph vessel development(GO:0001945) |
0.0 | 0.0 | GO:0002946 | tRNA C5-cytosine methylation(GO:0002946) |
0.0 | 0.6 | GO:0000186 | activation of MAPKK activity(GO:0000186) |
0.0 | 0.3 | GO:1902857 | positive regulation of nonmotile primary cilium assembly(GO:1902857) |
0.0 | 0.4 | GO:0032011 | ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012) |
0.0 | 4.5 | GO:0015833 | peptide transport(GO:0015833) |
0.0 | 1.8 | GO:0006865 | amino acid transport(GO:0006865) |
0.0 | 0.2 | GO:0003094 | glomerular filtration(GO:0003094) |
0.0 | 2.6 | GO:0015711 | organic anion transport(GO:0015711) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.6 | 13.0 | GO:0034706 | sodium channel complex(GO:0034706) |
0.2 | 2.9 | GO:0031045 | dense core granule(GO:0031045) |
0.1 | 1.1 | GO:0017071 | intracellular cyclic nucleotide activated cation channel complex(GO:0017071) |
0.1 | 3.3 | GO:0005922 | connexon complex(GO:0005922) |
0.1 | 0.9 | GO:0005726 | perichromatin fibrils(GO:0005726) |
0.1 | 1.2 | GO:0070578 | RISC-loading complex(GO:0070578) |
0.1 | 0.5 | GO:0042719 | mitochondrial intermembrane space protein transporter complex(GO:0042719) |
0.1 | 3.7 | GO:0035371 | microtubule plus-end(GO:0035371) |
0.1 | 1.1 | GO:0048787 | presynaptic active zone membrane(GO:0048787) |
0.1 | 0.8 | GO:0061617 | MICOS complex(GO:0061617) |
0.1 | 0.3 | GO:0097543 | ciliary inversin compartment(GO:0097543) |
0.1 | 1.1 | GO:0031232 | extrinsic component of external side of plasma membrane(GO:0031232) |
0.1 | 0.8 | GO:0000815 | ESCRT III complex(GO:0000815) |
0.1 | 2.3 | GO:0044215 | other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217) |
0.1 | 1.2 | GO:0071564 | npBAF complex(GO:0071564) |
0.1 | 2.3 | GO:0034364 | high-density lipoprotein particle(GO:0034364) |
0.0 | 0.6 | GO:0008385 | IkappaB kinase complex(GO:0008385) |
0.0 | 1.9 | GO:0045271 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
0.0 | 0.2 | GO:0032777 | Piccolo NuA4 histone acetyltransferase complex(GO:0032777) |
0.0 | 0.3 | GO:0030478 | actin cap(GO:0030478) |
0.0 | 0.2 | GO:0016602 | CCAAT-binding factor complex(GO:0016602) |
0.0 | 0.4 | GO:0005885 | Arp2/3 protein complex(GO:0005885) |
0.0 | 0.6 | GO:0005665 | DNA-directed RNA polymerase II, core complex(GO:0005665) |
0.0 | 0.3 | GO:0045298 | tubulin complex(GO:0045298) |
0.0 | 0.6 | GO:0043196 | varicosity(GO:0043196) |
0.0 | 0.3 | GO:0042788 | polysomal ribosome(GO:0042788) |
0.0 | 0.3 | GO:0097197 | tetraspanin-enriched microdomain(GO:0097197) |
0.0 | 0.4 | GO:0012507 | ER to Golgi transport vesicle membrane(GO:0012507) |
0.0 | 1.7 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
0.0 | 0.3 | GO:0031105 | septin complex(GO:0031105) |
0.0 | 1.8 | GO:0000118 | histone deacetylase complex(GO:0000118) |
0.0 | 1.5 | GO:0031526 | brush border membrane(GO:0031526) |
0.0 | 0.2 | GO:0031315 | extrinsic component of mitochondrial outer membrane(GO:0031315) |
0.0 | 0.5 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.1 | 12.6 | GO:0015280 | ligand-gated sodium channel activity(GO:0015280) |
0.7 | 2.9 | GO:0030348 | syntaxin-3 binding(GO:0030348) |
0.4 | 1.8 | GO:0005275 | amine transmembrane transporter activity(GO:0005275) |
0.3 | 1.5 | GO:0030292 | protein tyrosine kinase inhibitor activity(GO:0030292) |
0.3 | 2.3 | GO:0001849 | complement component C1q binding(GO:0001849) |
0.3 | 2.4 | GO:0004630 | phospholipase D activity(GO:0004630) |
0.2 | 3.3 | GO:0005243 | gap junction channel activity(GO:0005243) |
0.2 | 0.6 | GO:0008900 | hydrogen:potassium-exchanging ATPase activity(GO:0008900) |
0.2 | 1.2 | GO:0070883 | pre-miRNA binding(GO:0070883) |
0.2 | 1.1 | GO:0005052 | peroxisome matrix targeting signal-1 binding(GO:0005052) |
0.2 | 1.1 | GO:0004065 | arylsulfatase activity(GO:0004065) |
0.2 | 1.5 | GO:0031419 | cobalamin binding(GO:0031419) |
0.2 | 1.4 | GO:0032564 | dATP binding(GO:0032564) |
0.1 | 0.4 | GO:0043183 | vascular endothelial growth factor receptor 1 binding(GO:0043183) |
0.1 | 1.8 | GO:0019855 | calcium channel inhibitor activity(GO:0019855) |
0.1 | 0.9 | GO:0034056 | estrogen response element binding(GO:0034056) |
0.1 | 1.3 | GO:0070324 | thyroid hormone binding(GO:0070324) |
0.1 | 0.4 | GO:0051431 | corticotropin-releasing hormone receptor 2 binding(GO:0051431) |
0.1 | 13.9 | GO:0005179 | hormone activity(GO:0005179) |
0.1 | 1.3 | GO:0097157 | pre-mRNA intronic binding(GO:0097157) |
0.1 | 0.8 | GO:0005113 | patched binding(GO:0005113) |
0.1 | 1.9 | GO:0048038 | quinone binding(GO:0048038) |
0.1 | 0.4 | GO:0005008 | hepatocyte growth factor-activated receptor activity(GO:0005008) |
0.1 | 0.6 | GO:0033142 | progesterone receptor binding(GO:0033142) |
0.1 | 1.7 | GO:0004089 | carbonate dehydratase activity(GO:0004089) |
0.1 | 1.8 | GO:0030169 | signaling pattern recognition receptor activity(GO:0008329) low-density lipoprotein particle binding(GO:0030169) pattern recognition receptor activity(GO:0038187) |
0.1 | 1.3 | GO:0042809 | vitamin D receptor binding(GO:0042809) |
0.1 | 1.7 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
0.1 | 0.3 | GO:0005146 | leukemia inhibitory factor receptor binding(GO:0005146) |
0.1 | 5.4 | GO:0016811 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811) |
0.1 | 1.6 | GO:0005242 | inward rectifier potassium channel activity(GO:0005242) |
0.0 | 1.0 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
0.0 | 1.4 | GO:0042165 | neurotransmitter binding(GO:0042165) |
0.0 | 1.2 | GO:0016881 | acid-amino acid ligase activity(GO:0016881) |
0.0 | 1.2 | GO:0016922 | ligand-dependent nuclear receptor binding(GO:0016922) |
0.0 | 1.7 | GO:0005484 | SNAP receptor activity(GO:0005484) |
0.0 | 7.7 | GO:0015293 | symporter activity(GO:0015293) |
0.0 | 0.2 | GO:0070579 | methylcytosine dioxygenase activity(GO:0070579) |
0.0 | 1.0 | GO:0019707 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707) |
0.0 | 0.5 | GO:0031402 | sodium ion binding(GO:0031402) |
0.0 | 0.5 | GO:0043560 | insulin receptor substrate binding(GO:0043560) |
0.0 | 0.9 | GO:0004623 | phospholipase A2 activity(GO:0004623) |
0.0 | 0.6 | GO:0015269 | calcium-activated potassium channel activity(GO:0015269) |
0.0 | 0.6 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
0.0 | 0.4 | GO:0005132 | type I interferon receptor binding(GO:0005132) |
0.0 | 0.3 | GO:0003708 | retinoic acid receptor activity(GO:0003708) |
0.0 | 0.2 | GO:0050815 | phosphoserine binding(GO:0050815) |
0.0 | 0.3 | GO:0015250 | water channel activity(GO:0015250) |
0.0 | 0.4 | GO:0070006 | metalloaminopeptidase activity(GO:0070006) |
0.0 | 0.3 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
0.0 | 0.1 | GO:0008454 | alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454) |
0.0 | 0.7 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
0.0 | 3.5 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
0.0 | 0.4 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
0.0 | 0.1 | GO:0004652 | polynucleotide adenylyltransferase activity(GO:0004652) |
0.0 | 0.4 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 2.9 | SIG CD40PATHWAYMAP | Genes related to CD40 signaling |
0.0 | 2.4 | PID UPA UPAR PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
0.0 | 0.4 | PID VEGF VEGFR PATHWAY | VEGF and VEGFR signaling network |
0.0 | 0.6 | PID ERB GENOMIC PATHWAY | Validated nuclear estrogen receptor beta network |
0.0 | 0.8 | PID HEDGEHOG 2PATHWAY | Signaling events mediated by the Hedgehog family |
0.0 | 1.3 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
0.0 | 1.2 | PID CERAMIDE PATHWAY | Ceramide signaling pathway |
0.0 | 0.8 | ST JNK MAPK PATHWAY | JNK MAPK Pathway |
0.0 | 1.4 | PID LKB1 PATHWAY | LKB1 signaling events |
0.0 | 0.9 | PID AR TF PATHWAY | Regulation of Androgen receptor activity |
0.0 | 1.4 | PID P73PATHWAY | p73 transcription factor network |
0.0 | 0.3 | PID RETINOIC ACID PATHWAY | Retinoic acid receptors-mediated signaling |
0.0 | 2.1 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
0.0 | 0.4 | PID A6B1 A6B4 INTEGRIN PATHWAY | a6b1 and a6b4 Integrin signaling |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 3.0 | REACTOME CREATION OF C4 AND C2 ACTIVATORS | Genes involved in Creation of C4 and C2 activators |
0.3 | 5.4 | REACTOME TRYPTOPHAN CATABOLISM | Genes involved in Tryptophan catabolism |
0.2 | 2.9 | REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Acetylcholine Neurotransmitter Release Cycle |
0.2 | 2.9 | REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
0.2 | 3.3 | REACTOME GAP JUNCTION ASSEMBLY | Genes involved in Gap junction assembly |
0.1 | 1.1 | REACTOME THE ACTIVATION OF ARYLSULFATASES | Genes involved in The activation of arylsulfatases |
0.1 | 1.1 | REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS | Genes involved in Proteolytic cleavage of SNARE complex proteins |
0.1 | 1.8 | REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS | Genes involved in Na+/Cl- dependent neurotransmitter transporters |
0.1 | 1.2 | REACTOME VITAMIN B5 PANTOTHENATE METABOLISM | Genes involved in Vitamin B5 (pantothenate) metabolism |
0.1 | 2.4 | REACTOME SIGNALING BY FGFR1 FUSION MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |
0.1 | 1.8 | REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA | Genes involved in Circadian Repression of Expression by REV-ERBA |
0.0 | 0.9 | REACTOME TRAF6 MEDIATED IRF7 ACTIVATION | Genes involved in TRAF6 mediated IRF7 activation |
0.0 | 0.4 | REACTOME VEGF LIGAND RECEPTOR INTERACTIONS | Genes involved in VEGF ligand-receptor interactions |
0.0 | 1.8 | REACTOME VOLTAGE GATED POTASSIUM CHANNELS | Genes involved in Voltage gated Potassium channels |
0.0 | 1.9 | REACTOME RESPIRATORY ELECTRON TRANSPORT | Genes involved in Respiratory electron transport |
0.0 | 0.8 | REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT | Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT) |
0.0 | 1.3 | REACTOME AMYLOIDS | Genes involved in Amyloids |
0.0 | 0.5 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
0.0 | 0.2 | REACTOME RAF MAP KINASE CASCADE | Genes involved in RAF/MAP kinase cascade |
0.0 | 0.6 | REACTOME MYOGENESIS | Genes involved in Myogenesis |
0.0 | 0.5 | REACTOME CGMP EFFECTS | Genes involved in cGMP effects |
0.0 | 0.6 | REACTOME ION TRANSPORT BY P TYPE ATPASES | Genes involved in Ion transport by P-type ATPases |
0.0 | 0.2 | REACTOME AMINE DERIVED HORMONES | Genes involved in Amine-derived hormones |
0.0 | 0.4 | REACTOME SEMA4D IN SEMAPHORIN SIGNALING | Genes involved in Sema4D in semaphorin signaling |