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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for GGCAAGA

Z-value: 0.55

Motif logo

miRNA associated with seed GGCAAGA

NamemiRBASE accession
MIMAT0000538

Activity profile of GGCAAGA motif

Sorted Z-values of GGCAAGA motif

Network of associatons between targets according to the STRING database.

First level regulatory network of GGCAAGA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.2 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.2 0.5 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.1 0.4 GO:0016561 protein import into peroxisome matrix, translocation(GO:0016561)
0.1 0.5 GO:0043380 regulation of memory T cell differentiation(GO:0043380) negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.1 0.4 GO:1904954 canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation(GO:1904954)
0.1 0.2 GO:0030862 neuroblast division in subventricular zone(GO:0021849) positive regulation of polarized epithelial cell differentiation(GO:0030862)
0.1 0.5 GO:0061113 pancreas morphogenesis(GO:0061113)
0.1 0.6 GO:0045657 positive regulation of monocyte differentiation(GO:0045657)
0.1 0.2 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.1 0.2 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.1 0.2 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.2 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.0 0.6 GO:0042136 neurotransmitter biosynthetic process(GO:0042136)
0.0 0.1 GO:0021934 hindbrain tangential cell migration(GO:0021934)
0.0 0.3 GO:0051775 response to redox state(GO:0051775) negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.0 0.2 GO:0048104 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
0.0 0.2 GO:0098961 dendritic transport of ribonucleoprotein complex(GO:0098961) dendritic transport of messenger ribonucleoprotein complex(GO:0098963) anterograde dendritic transport of messenger ribonucleoprotein complex(GO:0098964)
0.0 0.3 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.1 GO:1900275 negative regulation of phospholipase C activity(GO:1900275)
0.0 0.2 GO:1902965 regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
0.0 0.1 GO:0090327 negative regulation of locomotion involved in locomotory behavior(GO:0090327)
0.0 0.2 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.1 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.0 0.1 GO:1902071 regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
0.0 0.1 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.0 0.2 GO:0097647 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 0.1 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.0 0.1 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.0 0.5 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.2 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.1 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.0 0.1 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.0 0.1 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.0 0.6 GO:0072348 sulfur compound transport(GO:0072348)
0.0 0.0 GO:0035964 COPI-coated vesicle budding(GO:0035964)
0.0 0.1 GO:1904684 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984) negative regulation of metalloendopeptidase activity(GO:1904684)
0.0 0.2 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.1 GO:0018211 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 0.1 GO:1903750 regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
0.0 0.2 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 0.0 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092) regulation of zinc ion transport(GO:0071579)
0.0 0.5 GO:0003016 respiratory system process(GO:0003016)
0.0 0.1 GO:0001827 inner cell mass cell fate commitment(GO:0001827)
0.0 0.2 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.1 GO:1904017 response to Thyroglobulin triiodothyronine(GO:1904016) cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.0 0.1 GO:0045176 apical protein localization(GO:0045176)
0.0 0.1 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996) regulation of establishment of protein localization to plasma membrane(GO:0090003)
0.0 0.5 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.1 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.3 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
0.0 0.0 GO:0097065 anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744)
0.0 0.1 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.2 GO:0030673 axolemma(GO:0030673)
0.1 0.2 GO:0060187 cell pole(GO:0060187)
0.0 0.2 GO:0097450 astrocyte end-foot(GO:0097450)
0.0 0.3 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.2 GO:1903439 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.0 0.2 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.4 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.1 GO:0033648 host intracellular organelle(GO:0033647) host intracellular membrane-bounded organelle(GO:0033648)
0.0 0.5 GO:0097440 apical dendrite(GO:0097440)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.2 0.6 GO:0030977 taurine binding(GO:0030977)
0.2 0.6 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.1 0.4 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.1 0.2 GO:0004356 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211)
0.1 0.2 GO:0035276 ethanol binding(GO:0035276)
0.1 0.2 GO:0004948 calcitonin receptor activity(GO:0004948)
0.0 0.2 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.6 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.0 0.2 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.1 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.2 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.3 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.1 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.1 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.1 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 0.1 GO:0031699 beta-3 adrenergic receptor binding(GO:0031699)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.4 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.1 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.1 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.2 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.6 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.3 GO:0005537 mannose binding(GO:0005537)
0.0 0.2 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313)
0.0 0.2 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.0 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.0 0.2 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.1 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.1 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.2 GO:0031489 myosin V binding(GO:0031489)
0.0 0.1 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.4 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.2 PID CIRCADIAN PATHWAY Circadian rhythm pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.9 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.8 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.1 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 0.2 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.2 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.3 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.5 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development