avrg: GSE58827: Dynamics of the Mouse Liver
Gene Symbol | Gene ID | Gene Info |
---|---|---|
Tcf7l1
|
ENSMUSG00000055799.7 | transcription factor 7 like 1 (T cell specific, HMG box) |
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Tcf7l1 | mm10_v2_chr6_-_72789240_72789262 | 0.63 | 4.4e-05 | Click! |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.2 | 3.6 | GO:0060217 | hemangioblast cell differentiation(GO:0060217) |
1.2 | 3.5 | GO:0002842 | positive regulation of T cell mediated immune response to tumor cell(GO:0002842) |
0.9 | 2.7 | GO:0034635 | glutathione transport(GO:0034635) tripeptide transport(GO:0042939) |
0.8 | 2.5 | GO:0033624 | negative regulation of integrin activation(GO:0033624) |
0.7 | 2.1 | GO:0002314 | germinal center B cell differentiation(GO:0002314) |
0.6 | 7.4 | GO:0006977 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977) |
0.5 | 4.2 | GO:0070294 | renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294) |
0.5 | 3.7 | GO:0006776 | vitamin A metabolic process(GO:0006776) |
0.4 | 2.5 | GO:0003100 | regulation of systemic arterial blood pressure by endothelin(GO:0003100) vein smooth muscle contraction(GO:0014826) |
0.4 | 1.2 | GO:2000620 | positive regulation of histone H4-K16 acetylation(GO:2000620) |
0.3 | 1.4 | GO:0046351 | disaccharide biosynthetic process(GO:0046351) |
0.3 | 1.4 | GO:0021812 | neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812) |
0.3 | 1.4 | GO:0060031 | mediolateral intercalation(GO:0060031) planar cell polarity pathway involved in gastrula mediolateral intercalation(GO:0060775) |
0.3 | 1.3 | GO:1904616 | regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616) |
0.3 | 1.9 | GO:0002528 | regulation of vascular permeability involved in acute inflammatory response(GO:0002528) |
0.3 | 0.9 | GO:0043396 | corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) positive regulation of corticotropin-releasing hormone secretion(GO:0051466) regulation of G-protein coupled receptor internalization(GO:1904020) |
0.3 | 1.2 | GO:0015827 | aromatic amino acid transport(GO:0015801) tryptophan transport(GO:0015827) |
0.3 | 0.9 | GO:0007494 | midgut development(GO:0007494) |
0.3 | 0.9 | GO:0010643 | cell communication by chemical coupling(GO:0010643) negative regulation of locomotion involved in locomotory behavior(GO:0090327) |
0.3 | 1.1 | GO:0071899 | negative regulation of interleukin-13 production(GO:0032696) regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899) |
0.2 | 0.7 | GO:0043553 | negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) |
0.2 | 3.6 | GO:0015809 | arginine transport(GO:0015809) |
0.2 | 1.1 | GO:0060244 | negative regulation of cell proliferation involved in contact inhibition(GO:0060244) |
0.2 | 0.9 | GO:0033575 | protein glycosylation at cell surface(GO:0033575) protein galactosylation at cell surface(GO:0033580) protein galactosylation(GO:0042125) |
0.2 | 1.6 | GO:0038026 | reelin-mediated signaling pathway(GO:0038026) |
0.2 | 1.9 | GO:0005513 | detection of calcium ion(GO:0005513) |
0.2 | 0.8 | GO:0010936 | negative regulation of macrophage cytokine production(GO:0010936) |
0.2 | 1.0 | GO:2000672 | negative regulation of motor neuron apoptotic process(GO:2000672) |
0.2 | 0.5 | GO:0071707 | immunoglobulin heavy chain V-D-J recombination(GO:0071707) |
0.2 | 0.5 | GO:0032241 | positive regulation of nucleobase-containing compound transport(GO:0032241) |
0.2 | 0.6 | GO:1902202 | regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202) negative regulation of PERK-mediated unfolded protein response(GO:1903898) |
0.1 | 1.2 | GO:0051388 | positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388) |
0.1 | 0.9 | GO:0010966 | regulation of phosphate transport(GO:0010966) |
0.1 | 0.6 | GO:0009212 | dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) dTTP metabolic process(GO:0046075) |
0.1 | 0.7 | GO:0002225 | positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803) |
0.1 | 3.2 | GO:0007614 | short-term memory(GO:0007614) |
0.1 | 1.4 | GO:0089711 | L-glutamate transmembrane transport(GO:0089711) L-alpha-amino acid transmembrane transport(GO:1902475) |
0.1 | 0.9 | GO:0045876 | positive regulation of sister chromatid cohesion(GO:0045876) |
0.1 | 0.6 | GO:0007403 | glial cell fate determination(GO:0007403) |
0.1 | 0.7 | GO:0071494 | cellular response to UV-C(GO:0071494) |
0.1 | 1.6 | GO:0006654 | phosphatidic acid biosynthetic process(GO:0006654) |
0.1 | 0.3 | GO:0034395 | regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395) |
0.1 | 2.7 | GO:0048368 | lateral mesoderm development(GO:0048368) |
0.1 | 1.2 | GO:1901250 | regulation of lung goblet cell differentiation(GO:1901249) negative regulation of lung goblet cell differentiation(GO:1901250) |
0.1 | 1.7 | GO:0061179 | negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179) |
0.1 | 0.8 | GO:0030644 | cellular chloride ion homeostasis(GO:0030644) |
0.1 | 1.9 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
0.1 | 1.3 | GO:0060539 | diaphragm development(GO:0060539) |
0.1 | 0.5 | GO:0015015 | heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015) |
0.1 | 0.3 | GO:0007208 | phospholipase C-activating serotonin receptor signaling pathway(GO:0007208) |
0.1 | 1.1 | GO:0014807 | regulation of somitogenesis(GO:0014807) |
0.1 | 1.2 | GO:1904659 | glucose transmembrane transport(GO:1904659) |
0.1 | 0.3 | GO:1900368 | regulation of RNA interference(GO:1900368) |
0.1 | 0.9 | GO:0016446 | somatic diversification of immune receptors via somatic mutation(GO:0002566) somatic hypermutation of immunoglobulin genes(GO:0016446) |
0.1 | 0.3 | GO:1904425 | negative regulation of GTP binding(GO:1904425) |
0.1 | 3.7 | GO:1901998 | toxin transport(GO:1901998) |
0.1 | 1.5 | GO:0061436 | establishment of skin barrier(GO:0061436) |
0.1 | 0.3 | GO:0045578 | negative regulation of B cell differentiation(GO:0045578) |
0.1 | 0.7 | GO:2000741 | positive regulation of mesenchymal stem cell differentiation(GO:2000741) |
0.1 | 0.5 | GO:0016576 | histone dephosphorylation(GO:0016576) |
0.1 | 0.7 | GO:0033623 | regulation of integrin activation(GO:0033623) |
0.1 | 2.1 | GO:0060065 | uterus development(GO:0060065) |
0.1 | 1.7 | GO:0032011 | ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012) |
0.1 | 0.4 | GO:0014816 | skeletal muscle satellite cell differentiation(GO:0014816) |
0.1 | 0.5 | GO:0051152 | positive regulation of smooth muscle cell differentiation(GO:0051152) |
0.0 | 0.6 | GO:0051292 | nuclear pore complex assembly(GO:0051292) |
0.0 | 2.7 | GO:0006509 | membrane protein ectodomain proteolysis(GO:0006509) |
0.0 | 0.4 | GO:1903715 | regulation of aerobic respiration(GO:1903715) |
0.0 | 0.2 | GO:0030576 | Cajal body organization(GO:0030576) |
0.0 | 0.4 | GO:0048539 | bone marrow development(GO:0048539) |
0.0 | 1.1 | GO:1990126 | retrograde transport, endosome to plasma membrane(GO:1990126) |
0.0 | 0.7 | GO:2000480 | negative regulation of cAMP-dependent protein kinase activity(GO:2000480) |
0.0 | 0.4 | GO:0035372 | protein localization to microtubule(GO:0035372) |
0.0 | 0.4 | GO:0061302 | smooth muscle cell-matrix adhesion(GO:0061302) |
0.0 | 0.1 | GO:2000382 | positive regulation of mesoderm development(GO:2000382) |
0.0 | 0.2 | GO:0035280 | miRNA loading onto RISC involved in gene silencing by miRNA(GO:0035280) |
0.0 | 0.7 | GO:0043374 | CD8-positive, alpha-beta T cell differentiation(GO:0043374) |
0.0 | 0.8 | GO:0071260 | cellular response to mechanical stimulus(GO:0071260) |
0.0 | 0.3 | GO:0045617 | negative regulation of keratinocyte differentiation(GO:0045617) |
0.0 | 0.2 | GO:0060339 | negative regulation of type I interferon-mediated signaling pathway(GO:0060339) |
0.0 | 0.2 | GO:0070934 | CRD-mediated mRNA stabilization(GO:0070934) positive regulation of cytoplasmic translation(GO:2000767) |
0.0 | 3.0 | GO:0032024 | positive regulation of insulin secretion(GO:0032024) |
0.0 | 0.8 | GO:0016242 | negative regulation of macroautophagy(GO:0016242) |
0.0 | 1.5 | GO:0071300 | cellular response to retinoic acid(GO:0071300) |
0.0 | 1.6 | GO:0043029 | T cell homeostasis(GO:0043029) |
0.0 | 2.5 | GO:0055092 | cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092) |
0.0 | 0.0 | GO:0060983 | epicardium-derived cardiac vascular smooth muscle cell differentiation(GO:0060983) |
0.0 | 0.3 | GO:0010587 | miRNA catabolic process(GO:0010587) |
0.0 | 0.5 | GO:0043968 | histone H2A acetylation(GO:0043968) |
0.0 | 1.1 | GO:1902042 | negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042) |
0.0 | 0.8 | GO:0034308 | primary alcohol metabolic process(GO:0034308) |
0.0 | 0.3 | GO:2000465 | regulation of glycogen (starch) synthase activity(GO:2000465) |
0.0 | 4.7 | GO:0008654 | phospholipid biosynthetic process(GO:0008654) |
0.0 | 0.8 | GO:0090162 | establishment of epithelial cell polarity(GO:0090162) |
0.0 | 0.2 | GO:0045607 | regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980) |
0.0 | 0.5 | GO:0042711 | maternal behavior(GO:0042711) |
0.0 | 0.4 | GO:1903204 | negative regulation of oxidative stress-induced neuron death(GO:1903204) |
0.0 | 0.2 | GO:0071233 | response to leucine(GO:0043201) cellular response to leucine(GO:0071233) |
0.0 | 0.1 | GO:2000686 | regulation of rubidium ion transmembrane transporter activity(GO:2000686) |
0.0 | 0.2 | GO:0034498 | early endosome to Golgi transport(GO:0034498) |
0.0 | 0.4 | GO:0007289 | spermatid nucleus differentiation(GO:0007289) |
0.0 | 0.8 | GO:0046627 | negative regulation of insulin receptor signaling pathway(GO:0046627) |
0.0 | 0.8 | GO:0002437 | inflammatory response to antigenic stimulus(GO:0002437) |
0.0 | 2.2 | GO:0007050 | cell cycle arrest(GO:0007050) |
0.0 | 0.3 | GO:0045056 | transcytosis(GO:0045056) |
0.0 | 0.9 | GO:0006611 | protein export from nucleus(GO:0006611) |
0.0 | 0.1 | GO:0007158 | neuron cell-cell adhesion(GO:0007158) |
0.0 | 0.5 | GO:0045746 | negative regulation of Notch signaling pathway(GO:0045746) |
0.0 | 3.7 | GO:0016485 | protein processing(GO:0016485) |
0.0 | 1.1 | GO:0032091 | negative regulation of protein binding(GO:0032091) |
0.0 | 0.4 | GO:0034723 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) |
0.0 | 0.3 | GO:0031424 | keratinization(GO:0031424) |
0.0 | 0.4 | GO:0009409 | response to cold(GO:0009409) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.2 | 3.6 | GO:0033193 | Lsd1/2 complex(GO:0033193) |
1.0 | 3.0 | GO:0071149 | TEAD-2-YAP complex(GO:0071149) |
0.5 | 1.4 | GO:0005607 | laminin-2 complex(GO:0005607) |
0.2 | 1.0 | GO:0097058 | CRLF-CLCF1 complex(GO:0097058) |
0.2 | 0.9 | GO:1902737 | dendritic filopodium(GO:1902737) |
0.2 | 0.5 | GO:0038045 | large latent transforming growth factor-beta complex(GO:0038045) |
0.2 | 1.6 | GO:0001739 | sex chromatin(GO:0001739) |
0.1 | 0.9 | GO:0044530 | supraspliceosomal complex(GO:0044530) |
0.1 | 0.7 | GO:0000308 | cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308) |
0.1 | 3.2 | GO:0031362 | anchored component of external side of plasma membrane(GO:0031362) |
0.1 | 0.8 | GO:0005726 | perichromatin fibrils(GO:0005726) |
0.1 | 0.9 | GO:0042382 | paraspeckles(GO:0042382) |
0.1 | 1.1 | GO:1990907 | beta-catenin-TCF complex(GO:1990907) |
0.1 | 0.3 | GO:0042272 | nucleocytoplasmic shuttling complex(GO:0031074) nuclear RNA export factor complex(GO:0042272) |
0.1 | 0.6 | GO:0097443 | sorting endosome(GO:0097443) |
0.1 | 0.4 | GO:0008623 | CHRAC(GO:0008623) |
0.1 | 0.6 | GO:0005672 | transcription factor TFIIA complex(GO:0005672) |
0.1 | 0.2 | GO:0030905 | retromer, tubulation complex(GO:0030905) |
0.1 | 0.9 | GO:0044294 | dendritic growth cone(GO:0044294) |
0.1 | 0.2 | GO:0044094 | host cell nucleus(GO:0042025) host cell nuclear part(GO:0044094) |
0.1 | 2.5 | GO:0051233 | spindle midzone(GO:0051233) |
0.1 | 1.5 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
0.1 | 1.1 | GO:0017146 | NMDA selective glutamate receptor complex(GO:0017146) |
0.0 | 2.1 | GO:0016460 | myosin II complex(GO:0016460) |
0.0 | 1.0 | GO:0016580 | Sin3 complex(GO:0016580) |
0.0 | 0.2 | GO:1990032 | parallel fiber(GO:1990032) |
0.0 | 0.1 | GO:0043224 | nuclear SCF ubiquitin ligase complex(GO:0043224) |
0.0 | 0.5 | GO:0031011 | Ino80 complex(GO:0031011) |
0.0 | 0.2 | GO:1990131 | Gtr1-Gtr2 GTPase complex(GO:1990131) |
0.0 | 1.7 | GO:0097610 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
0.0 | 0.5 | GO:0036038 | MKS complex(GO:0036038) |
0.0 | 0.6 | GO:0042599 | lamellar body(GO:0042599) |
0.0 | 0.2 | GO:0035068 | micro-ribonucleoprotein complex(GO:0035068) |
0.0 | 0.2 | GO:0005638 | lamin filament(GO:0005638) |
0.0 | 0.5 | GO:0005685 | U1 snRNP(GO:0005685) |
0.0 | 0.5 | GO:0045120 | pronucleus(GO:0045120) |
0.0 | 1.8 | GO:0030175 | filopodium(GO:0030175) |
0.0 | 1.9 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
0.0 | 5.7 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
0.0 | 0.9 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
0.0 | 0.9 | GO:0031985 | Golgi cisterna(GO:0031985) |
0.0 | 1.6 | GO:0030496 | midbody(GO:0030496) |
0.0 | 1.3 | GO:0005791 | rough endoplasmic reticulum(GO:0005791) |
0.0 | 1.1 | GO:0005901 | caveola(GO:0005901) |
0.0 | 0.4 | GO:0001533 | cornified envelope(GO:0001533) |
0.0 | 1.6 | GO:0043204 | perikaryon(GO:0043204) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.7 | 2.1 | GO:0035673 | oligopeptide transmembrane transporter activity(GO:0035673) |
0.6 | 3.7 | GO:0047184 | 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184) |
0.6 | 2.5 | GO:0031708 | endothelin B receptor binding(GO:0031708) |
0.5 | 1.4 | GO:0004461 | lactose synthase activity(GO:0004461) |
0.5 | 3.6 | GO:0015181 | arginine transmembrane transporter activity(GO:0015181) |
0.4 | 1.4 | GO:0038025 | reelin receptor activity(GO:0038025) |
0.3 | 1.7 | GO:0017077 | oxidative phosphorylation uncoupler activity(GO:0017077) |
0.3 | 2.7 | GO:0015651 | quaternary ammonium group transmembrane transporter activity(GO:0015651) |
0.3 | 1.9 | GO:0004687 | myosin light chain kinase activity(GO:0004687) |
0.3 | 1.6 | GO:0004111 | creatine kinase activity(GO:0004111) |
0.3 | 3.7 | GO:0016918 | retinal binding(GO:0016918) retinol binding(GO:0019841) |
0.2 | 1.4 | GO:0000099 | sulfur amino acid transmembrane transporter activity(GO:0000099) |
0.2 | 3.5 | GO:0030296 | protein tyrosine kinase activator activity(GO:0030296) |
0.2 | 2.6 | GO:0005522 | profilin binding(GO:0005522) |
0.2 | 1.2 | GO:0008241 | peptidyl-dipeptidase activity(GO:0008241) |
0.2 | 0.5 | GO:0008457 | beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256) |
0.2 | 0.7 | GO:0036313 | phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313) |
0.2 | 0.5 | GO:0050436 | microfibril binding(GO:0050436) |
0.2 | 1.4 | GO:0043208 | glycosphingolipid binding(GO:0043208) |
0.2 | 1.1 | GO:0030284 | estrogen receptor activity(GO:0030284) |
0.1 | 3.7 | GO:0031005 | filamin binding(GO:0031005) |
0.1 | 0.9 | GO:0047276 | N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276) |
0.1 | 1.1 | GO:0001075 | transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075) |
0.1 | 3.8 | GO:0004190 | aspartic-type endopeptidase activity(GO:0004190) |
0.1 | 2.7 | GO:0003841 | 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) |
0.1 | 0.5 | GO:0017095 | heparan sulfate 6-O-sulfotransferase activity(GO:0017095) |
0.1 | 1.9 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
0.1 | 0.9 | GO:0005113 | patched binding(GO:0005113) |
0.1 | 0.4 | GO:0047179 | platelet-activating factor acetyltransferase activity(GO:0047179) |
0.1 | 1.0 | GO:0005127 | ciliary neurotrophic factor receptor binding(GO:0005127) |
0.1 | 1.2 | GO:0005049 | nuclear export signal receptor activity(GO:0005049) |
0.1 | 2.5 | GO:0001134 | transcription factor activity, transcription factor recruiting(GO:0001134) |
0.1 | 0.5 | GO:0035614 | snRNA stem-loop binding(GO:0035614) |
0.1 | 2.5 | GO:0017128 | phospholipid scramblase activity(GO:0017128) |
0.1 | 1.2 | GO:0005412 | glucose:sodium symporter activity(GO:0005412) |
0.1 | 1.3 | GO:0015197 | peptide transporter activity(GO:0015197) |
0.1 | 0.3 | GO:0042954 | lipoprotein transporter activity(GO:0042954) |
0.1 | 0.3 | GO:2001069 | glycogen binding(GO:2001069) |
0.1 | 1.9 | GO:0015269 | calcium-activated potassium channel activity(GO:0015269) |
0.1 | 7.4 | GO:0003730 | mRNA 3'-UTR binding(GO:0003730) |
0.1 | 2.5 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
0.1 | 0.9 | GO:0005068 | transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068) |
0.1 | 0.3 | GO:0004952 | dopamine neurotransmitter receptor activity(GO:0004952) |
0.1 | 0.5 | GO:0046976 | histone methyltransferase activity (H3-K27 specific)(GO:0046976) |
0.1 | 1.2 | GO:0008409 | 5'-3' exonuclease activity(GO:0008409) |
0.1 | 0.8 | GO:0004185 | serine-type carboxypeptidase activity(GO:0004185) |
0.1 | 0.3 | GO:0050265 | RNA uridylyltransferase activity(GO:0050265) |
0.1 | 0.2 | GO:1990460 | leptin receptor binding(GO:1990460) |
0.1 | 0.2 | GO:0033680 | ATP-dependent DNA/RNA helicase activity(GO:0033680) |
0.1 | 3.0 | GO:0070888 | E-box binding(GO:0070888) |
0.0 | 1.2 | GO:0005092 | GDP-dissociation inhibitor activity(GO:0005092) |
0.0 | 1.7 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
0.0 | 0.4 | GO:0038062 | protein tyrosine kinase collagen receptor activity(GO:0038062) |
0.0 | 0.6 | GO:0001164 | RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164) |
0.0 | 0.4 | GO:1990459 | transferrin receptor binding(GO:1990459) |
0.0 | 0.7 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
0.0 | 0.8 | GO:0004622 | lysophospholipase activity(GO:0004622) |
0.0 | 0.3 | GO:0005095 | GTPase inhibitor activity(GO:0005095) |
0.0 | 0.7 | GO:0004862 | cAMP-dependent protein kinase inhibitor activity(GO:0004862) |
0.0 | 0.9 | GO:0071855 | neuropeptide receptor binding(GO:0071855) |
0.0 | 1.6 | GO:0042169 | SH2 domain binding(GO:0042169) |
0.0 | 0.2 | GO:0030368 | interleukin-17 receptor activity(GO:0030368) |
0.0 | 0.6 | GO:0017056 | structural constituent of nuclear pore(GO:0017056) |
0.0 | 0.5 | GO:0008266 | poly(U) RNA binding(GO:0008266) |
0.0 | 0.7 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
0.0 | 2.8 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
0.0 | 0.2 | GO:0035662 | Toll-like receptor 4 binding(GO:0035662) |
0.0 | 0.3 | GO:0051378 | serotonin binding(GO:0051378) |
0.0 | 0.4 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
0.0 | 0.2 | GO:0035198 | miRNA binding(GO:0035198) |
0.0 | 1.1 | GO:0001540 | beta-amyloid binding(GO:0001540) |
0.0 | 0.8 | GO:0050750 | low-density lipoprotein particle receptor binding(GO:0050750) |
0.0 | 1.4 | GO:0030295 | protein kinase activator activity(GO:0030295) |
0.0 | 0.1 | GO:0004910 | interleukin-1, Type II, blocking receptor activity(GO:0004910) |
0.0 | 0.7 | GO:0030332 | cyclin binding(GO:0030332) |
0.0 | 3.4 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
0.0 | 0.8 | GO:0001205 | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205) |
0.0 | 0.5 | GO:0005112 | Notch binding(GO:0005112) |
0.0 | 0.6 | GO:0051721 | protein phosphatase 2A binding(GO:0051721) |
0.0 | 0.1 | GO:0019788 | NEDD8 transferase activity(GO:0019788) |
0.0 | 0.5 | GO:0008138 | protein tyrosine/serine/threonine phosphatase activity(GO:0008138) |
0.0 | 1.8 | GO:0042826 | histone deacetylase binding(GO:0042826) |
0.0 | 0.2 | GO:0004535 | poly(A)-specific ribonuclease activity(GO:0004535) |
0.0 | 0.9 | GO:0003727 | single-stranded RNA binding(GO:0003727) |
0.0 | 0.9 | GO:0004714 | transmembrane receptor protein tyrosine kinase activity(GO:0004714) |
0.0 | 0.4 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 1.4 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
0.1 | 4.5 | PID AJDISS 2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
0.0 | 1.9 | PID P38 ALPHA BETA PATHWAY | Regulation of p38-alpha and p38-beta |
0.0 | 1.6 | PID HEDGEHOG 2PATHWAY | Signaling events mediated by the Hedgehog family |
0.0 | 1.7 | PID ECADHERIN NASCENT AJ PATHWAY | E-cadherin signaling in the nascent adherens junction |
0.0 | 2.0 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
0.0 | 0.6 | PID ERB GENOMIC PATHWAY | Validated nuclear estrogen receptor beta network |
0.0 | 1.4 | PID REELIN PATHWAY | Reelin signaling pathway |
0.0 | 2.2 | PID ENDOTHELIN PATHWAY | Endothelins |
0.0 | 0.9 | PID HDAC CLASSIII PATHWAY | Signaling events mediated by HDAC Class III |
0.0 | 2.4 | PID RB 1PATHWAY | Regulation of retinoblastoma protein |
0.0 | 0.9 | ST DIFFERENTIATION PATHWAY IN PC12 CELLS | Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway. |
0.0 | 0.5 | PID MYC PATHWAY | C-MYC pathway |
0.0 | 0.4 | PID EPHRINB REV PATHWAY | Ephrin B reverse signaling |
0.0 | 0.9 | PID IL4 2PATHWAY | IL4-mediated signaling events |
0.0 | 0.2 | PID FGF PATHWAY | FGF signaling pathway |
0.0 | 0.7 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 2.7 | REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT | Genes involved in Organic cation/anion/zwitterion transport |
0.1 | 3.7 | REACTOME ACYL CHAIN REMODELLING OF PC | Genes involved in Acyl chain remodelling of PC |
0.1 | 4.5 | REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
0.1 | 4.0 | REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D | Genes involved in Metabolism of steroid hormones and vitamins A and D |
0.1 | 2.7 | REACTOME SYNTHESIS OF PA | Genes involved in Synthesis of PA |
0.1 | 1.3 | REACTOME CRMPS IN SEMA3A SIGNALING | Genes involved in CRMPs in Sema3A signaling |
0.1 | 1.4 | REACTOME PLATELET SENSITIZATION BY LDL | Genes involved in Platelet sensitization by LDL |
0.1 | 0.9 | REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY | Genes involved in Post-chaperonin tubulin folding pathway |
0.1 | 1.9 | REACTOME CGMP EFFECTS | Genes involved in cGMP effects |
0.1 | 0.6 | REACTOME REGULATION OF IFNG SIGNALING | Genes involved in Regulation of IFNG signaling |
0.0 | 2.0 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
0.0 | 0.8 | REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE | Genes involved in Cytochrome P450 - arranged by substrate type |
0.0 | 0.9 | REACTOME TIE2 SIGNALING | Genes involved in Tie2 Signaling |
0.0 | 0.8 | REACTOME RNA POL III CHAIN ELONGATION | Genes involved in RNA Polymerase III Chain Elongation |
0.0 | 1.5 | REACTOME TIGHT JUNCTION INTERACTIONS | Genes involved in Tight junction interactions |
0.0 | 0.7 | REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
0.0 | 1.1 | REACTOME SIGNALING BY ROBO RECEPTOR | Genes involved in Signaling by Robo receptor |
0.0 | 0.3 | REACTOME SEROTONIN RECEPTORS | Genes involved in Serotonin receptors |
0.0 | 0.4 | REACTOME OTHER SEMAPHORIN INTERACTIONS | Genes involved in Other semaphorin interactions |
0.0 | 1.7 | REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS | Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. |
0.0 | 0.3 | REACTOME MICRORNA MIRNA BIOGENESIS | Genes involved in MicroRNA (miRNA) Biogenesis |
0.0 | 0.4 | REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 | Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1) |
0.0 | 0.5 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
0.0 | 0.5 | REACTOME HS GAG BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
0.0 | 1.4 | REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
0.0 | 1.6 | REACTOME MRNA SPLICING | Genes involved in mRNA Splicing |
0.0 | 0.7 | REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS | Genes involved in Apoptotic cleavage of cellular proteins |