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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Sox13

Z-value: 0.65

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Transcription factors associated with Sox13

Gene Symbol Gene ID Gene Info
ENSMUSG00000070643.5 SRY (sex determining region Y)-box 13

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Sox13mm10_v2_chr1_-_133424377_1334244040.316.6e-02Click!

Activity profile of Sox13 motif

Sorted Z-values of Sox13 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Sox13

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:2000016 negative regulation of determination of dorsal identity(GO:2000016)
0.1 3.5 GO:0045109 intermediate filament organization(GO:0045109)
0.1 0.4 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.1 0.4 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.1 2.9 GO:0097435 fibril organization(GO:0097435)
0.1 0.8 GO:0040009 regulation of growth rate(GO:0040009)
0.1 1.4 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.1 0.2 GO:0050973 detection of mechanical stimulus involved in equilibrioception(GO:0050973)
0.1 0.3 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.4 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.6 GO:0014029 neural crest formation(GO:0014029)
0.0 0.4 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.7 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.3 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.8 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.3 GO:0010748 negative regulation of B cell apoptotic process(GO:0002903) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.0 1.1 GO:0035411 catenin import into nucleus(GO:0035411)
0.0 0.3 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.2 GO:0046549 retinal cone cell development(GO:0046549)
0.0 0.2 GO:0046069 cGMP catabolic process(GO:0046069)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.2 2.9 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 3.5 GO:0005882 intermediate filament(GO:0005882)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.9 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.3 1.4 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1 1.6 GO:0036122 BMP binding(GO:0036122) BMP receptor activity(GO:0098821)
0.1 0.4 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 0.3 GO:0004111 creatine kinase activity(GO:0004111)
0.1 0.4 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
0.0 0.2 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.3 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.2 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.4 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.1 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 1.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.6 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.2 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.2 GO:0035198 miRNA binding(GO:0035198)
0.0 0.3 GO:0015269 calcium-activated potassium channel activity(GO:0015269)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.8 PID BMP PATHWAY BMP receptor signaling
0.0 2.9 PID NOTCH PATHWAY Notch signaling pathway
0.0 1.4 PID E2F PATHWAY E2F transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.3 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling