avrg: GSE58827: Dynamics of the Mouse Liver
Gene Symbol | Gene ID | Gene Info |
---|---|---|
Stat2
|
ENSMUSG00000040033.9 | signal transducer and activator of transcription 2 |
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Stat2 | mm10_v2_chr10_+_128270546_128270577 | 0.71 | 1.0e-06 | Click! |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
3.4 | 13.6 | GO:0002415 | immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415) |
3.3 | 10.0 | GO:2000547 | regulation of dendritic cell dendrite assembly(GO:2000547) |
2.7 | 8.0 | GO:1990166 | protein localization to site of double-strand break(GO:1990166) |
2.1 | 6.3 | GO:0006533 | aspartate catabolic process(GO:0006533) |
1.9 | 5.7 | GO:1904933 | regulation of cell proliferation in midbrain(GO:1904933) |
1.3 | 5.2 | GO:0061762 | CAMKK-AMPK signaling cascade(GO:0061762) |
1.1 | 2.1 | GO:0002589 | regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) |
1.0 | 3.1 | GO:0009258 | 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560) |
1.0 | 4.2 | GO:0006556 | S-adenosylmethionine biosynthetic process(GO:0006556) |
1.0 | 3.0 | GO:1900245 | positive regulation of MDA-5 signaling pathway(GO:1900245) |
1.0 | 4.9 | GO:0046967 | cytosol to ER transport(GO:0046967) |
1.0 | 3.8 | GO:0070212 | protein poly-ADP-ribosylation(GO:0070212) |
0.9 | 5.7 | GO:0018992 | germ-line sex determination(GO:0018992) |
0.9 | 1.9 | GO:0002481 | antigen processing and presentation of exogenous peptide antigen via MHC class Ib(GO:0002477) antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent(GO:0002481) |
0.9 | 23.2 | GO:0035455 | response to interferon-alpha(GO:0035455) |
0.8 | 3.3 | GO:2000503 | positive regulation of natural killer cell chemotaxis(GO:2000503) |
0.8 | 3.1 | GO:2000562 | negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562) |
0.7 | 3.3 | GO:0060335 | positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335) |
0.7 | 3.9 | GO:1900142 | regulation of oligodendrocyte apoptotic process(GO:1900141) negative regulation of oligodendrocyte apoptotic process(GO:1900142) regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075) |
0.6 | 5.8 | GO:0072602 | interleukin-4 secretion(GO:0072602) |
0.6 | 3.7 | GO:0035549 | interferon-beta secretion(GO:0035546) regulation of interferon-beta secretion(GO:0035547) positive regulation of interferon-beta secretion(GO:0035549) |
0.6 | 3.7 | GO:0019805 | quinolinate biosynthetic process(GO:0019805) |
0.6 | 9.3 | GO:0031000 | response to caffeine(GO:0031000) |
0.6 | 7.9 | GO:0060340 | positive regulation of type I interferon-mediated signaling pathway(GO:0060340) |
0.5 | 1.6 | GO:0048698 | negative regulation of collateral sprouting in absence of injury(GO:0048698) |
0.5 | 3.0 | GO:1900170 | negative regulation of glucocorticoid mediated signaling pathway(GO:1900170) |
0.5 | 3.8 | GO:1990504 | dense core granule exocytosis(GO:1990504) |
0.4 | 16.3 | GO:0035456 | response to interferon-beta(GO:0035456) |
0.4 | 1.2 | GO:0070904 | L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904) |
0.4 | 1.2 | GO:0072276 | cell migration involved in vasculogenesis(GO:0035441) metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277) |
0.4 | 1.2 | GO:0046098 | guanine metabolic process(GO:0046098) |
0.4 | 1.9 | GO:0019885 | antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885) |
0.4 | 2.9 | GO:0051138 | positive regulation of NK T cell differentiation(GO:0051138) |
0.4 | 2.1 | GO:0021853 | cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936) |
0.3 | 1.0 | GO:0060809 | mesodermal to mesenchymal transition involved in gastrulation(GO:0060809) |
0.3 | 1.8 | GO:0003383 | apical constriction(GO:0003383) |
0.3 | 1.2 | GO:1901740 | negative regulation of myoblast fusion(GO:1901740) |
0.3 | 4.6 | GO:0006957 | complement activation, alternative pathway(GO:0006957) |
0.3 | 2.2 | GO:0045348 | positive regulation of MHC class II biosynthetic process(GO:0045348) |
0.3 | 1.1 | GO:0051562 | negative regulation of mitochondrial calcium ion concentration(GO:0051562) |
0.3 | 2.0 | GO:0015961 | diadenosine polyphosphate catabolic process(GO:0015961) |
0.2 | 11.7 | GO:0048247 | lymphocyte chemotaxis(GO:0048247) |
0.2 | 8.7 | GO:0032728 | positive regulation of interferon-beta production(GO:0032728) |
0.2 | 0.7 | GO:0060392 | negative regulation of SMAD protein import into nucleus(GO:0060392) |
0.2 | 3.5 | GO:0046485 | ether lipid metabolic process(GO:0046485) |
0.2 | 1.7 | GO:0060330 | regulation of response to interferon-gamma(GO:0060330) |
0.2 | 0.6 | GO:0007208 | phospholipase C-activating serotonin receptor signaling pathway(GO:0007208) |
0.2 | 3.6 | GO:0001580 | detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580) |
0.2 | 2.1 | GO:0014807 | regulation of somitogenesis(GO:0014807) |
0.2 | 4.5 | GO:0032897 | negative regulation of viral transcription(GO:0032897) |
0.2 | 0.6 | GO:1902867 | negative regulation of neural retina development(GO:0061076) negative regulation of retina development in camera-type eye(GO:1902867) negative regulation of amacrine cell differentiation(GO:1902870) |
0.2 | 1.7 | GO:0045078 | positive regulation of interferon-gamma biosynthetic process(GO:0045078) |
0.2 | 6.6 | GO:1901522 | positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522) |
0.2 | 0.5 | GO:0048687 | positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) |
0.2 | 1.2 | GO:0045351 | type I interferon biosynthetic process(GO:0045351) |
0.2 | 0.5 | GO:0072734 | response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734) |
0.2 | 1.8 | GO:0035810 | positive regulation of urine volume(GO:0035810) |
0.2 | 5.2 | GO:0046688 | response to copper ion(GO:0046688) |
0.2 | 2.6 | GO:0010623 | programmed cell death involved in cell development(GO:0010623) |
0.1 | 1.2 | GO:0060700 | regulation of ribonuclease activity(GO:0060700) |
0.1 | 1.1 | GO:0071357 | type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357) |
0.1 | 1.5 | GO:2000051 | negative regulation of non-canonical Wnt signaling pathway(GO:2000051) |
0.1 | 0.9 | GO:0010990 | regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991) |
0.1 | 1.8 | GO:1904262 | negative regulation of TORC1 signaling(GO:1904262) |
0.1 | 0.9 | GO:0090091 | positive regulation of extracellular matrix disassembly(GO:0090091) |
0.1 | 0.6 | GO:0051204 | protein insertion into mitochondrial membrane(GO:0051204) |
0.1 | 0.4 | GO:0016332 | establishment or maintenance of polarity of embryonic epithelium(GO:0016332) |
0.1 | 1.2 | GO:0070932 | histone H3 deacetylation(GO:0070932) |
0.1 | 4.9 | GO:0006953 | acute-phase response(GO:0006953) |
0.1 | 1.9 | GO:1902236 | negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236) |
0.1 | 0.5 | GO:1900226 | negative regulation of NLRP3 inflammasome complex assembly(GO:1900226) |
0.1 | 2.4 | GO:0035634 | response to stilbenoid(GO:0035634) |
0.1 | 1.7 | GO:0036295 | cellular response to increased oxygen levels(GO:0036295) |
0.1 | 10.4 | GO:0007586 | digestion(GO:0007586) |
0.1 | 5.0 | GO:0006687 | glycosphingolipid metabolic process(GO:0006687) |
0.1 | 0.9 | GO:0032494 | response to peptidoglycan(GO:0032494) |
0.1 | 0.5 | GO:0090234 | regulation of kinetochore assembly(GO:0090234) |
0.1 | 2.7 | GO:0048791 | calcium ion-regulated exocytosis of neurotransmitter(GO:0048791) |
0.1 | 0.3 | GO:0048014 | Tie signaling pathway(GO:0048014) |
0.1 | 0.2 | GO:0061386 | closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045) |
0.1 | 1.1 | GO:0021707 | cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707) |
0.1 | 0.2 | GO:1900169 | regulation of glucocorticoid mediated signaling pathway(GO:1900169) |
0.1 | 1.1 | GO:0042119 | neutrophil activation(GO:0042119) |
0.1 | 0.5 | GO:0048207 | vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) |
0.0 | 1.0 | GO:0042832 | defense response to protozoan(GO:0042832) |
0.0 | 0.2 | GO:0090168 | Golgi reassembly(GO:0090168) |
0.0 | 5.9 | GO:0019395 | fatty acid oxidation(GO:0019395) |
0.0 | 0.2 | GO:2001181 | positive regulation of interleukin-10 secretion(GO:2001181) |
0.0 | 1.9 | GO:0070207 | protein homotrimerization(GO:0070207) |
0.0 | 3.1 | GO:0010508 | positive regulation of autophagy(GO:0010508) |
0.0 | 1.5 | GO:0034341 | response to interferon-gamma(GO:0034341) |
0.0 | 0.4 | GO:0021678 | third ventricle development(GO:0021678) |
0.0 | 0.3 | GO:0002862 | negative regulation of inflammatory response to antigenic stimulus(GO:0002862) |
0.0 | 0.1 | GO:0003431 | growth plate cartilage chondrocyte development(GO:0003431) |
0.0 | 0.9 | GO:0002089 | lens morphogenesis in camera-type eye(GO:0002089) |
0.0 | 0.1 | GO:0043974 | histone H3-K27 acetylation(GO:0043974) leukemia inhibitory factor signaling pathway(GO:0048861) regulation of histone H3-K27 acetylation(GO:1901674) |
0.0 | 1.1 | GO:0071526 | semaphorin-plexin signaling pathway(GO:0071526) |
0.0 | 1.0 | GO:0046677 | response to antibiotic(GO:0046677) |
0.0 | 0.2 | GO:0060124 | positive regulation of growth hormone secretion(GO:0060124) |
0.0 | 0.5 | GO:0032689 | negative regulation of interferon-gamma production(GO:0032689) |
0.0 | 0.3 | GO:0048305 | immunoglobulin secretion(GO:0048305) |
0.0 | 0.5 | GO:0060765 | regulation of androgen receptor signaling pathway(GO:0060765) |
0.0 | 1.3 | GO:0019882 | antigen processing and presentation(GO:0019882) |
0.0 | 0.3 | GO:0008535 | respiratory chain complex IV assembly(GO:0008535) |
0.0 | 2.7 | GO:0007608 | sensory perception of smell(GO:0007608) |
0.0 | 1.8 | GO:0007286 | spermatid development(GO:0007286) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.9 | 12.7 | GO:0020003 | symbiont-containing vacuole(GO:0020003) |
0.7 | 5.5 | GO:0042825 | TAP complex(GO:0042825) |
0.4 | 3.9 | GO:0035867 | alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867) insulin-like growth factor ternary complex(GO:0042567) |
0.4 | 2.1 | GO:1990111 | spermatoproteasome complex(GO:1990111) |
0.4 | 3.2 | GO:1990712 | HFE-transferrin receptor complex(GO:1990712) |
0.3 | 1.3 | GO:0031084 | BLOC-2 complex(GO:0031084) |
0.3 | 13.6 | GO:0055038 | recycling endosome membrane(GO:0055038) |
0.2 | 1.8 | GO:0033269 | internode region of axon(GO:0033269) |
0.2 | 3.3 | GO:0044754 | autolysosome(GO:0044754) |
0.2 | 1.7 | GO:0033180 | proton-transporting V-type ATPase, V1 domain(GO:0033180) |
0.2 | 6.5 | GO:0035861 | site of double-strand break(GO:0035861) |
0.1 | 6.5 | GO:0031901 | early endosome membrane(GO:0031901) |
0.1 | 5.2 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
0.1 | 0.1 | GO:0005583 | fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643) |
0.1 | 3.3 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
0.1 | 8.1 | GO:0072562 | blood microparticle(GO:0072562) |
0.0 | 0.9 | GO:0033391 | chromatoid body(GO:0033391) |
0.0 | 3.1 | GO:0005776 | autophagosome(GO:0005776) |
0.0 | 2.0 | GO:0005637 | nuclear inner membrane(GO:0005637) |
0.0 | 3.8 | GO:0042734 | presynaptic membrane(GO:0042734) |
0.0 | 6.3 | GO:0042579 | peroxisome(GO:0005777) microbody(GO:0042579) |
0.0 | 53.5 | GO:0005615 | extracellular space(GO:0005615) |
0.0 | 6.5 | GO:0005741 | mitochondrial outer membrane(GO:0005741) |
0.0 | 12.0 | GO:0045177 | apical part of cell(GO:0045177) |
0.0 | 0.6 | GO:0031305 | integral component of mitochondrial inner membrane(GO:0031305) |
0.0 | 0.2 | GO:0033176 | proton-transporting V-type ATPase complex(GO:0033176) |
0.0 | 1.0 | GO:0032587 | ruffle membrane(GO:0032587) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.7 | 5.1 | GO:0003692 | left-handed Z-DNA binding(GO:0003692) |
1.6 | 6.3 | GO:0003884 | D-amino-acid oxidase activity(GO:0003884) |
1.5 | 6.0 | GO:0031735 | CCR10 chemokine receptor binding(GO:0031735) |
1.5 | 14.7 | GO:0019763 | immunoglobulin receptor activity(GO:0019763) |
1.4 | 5.8 | GO:0002114 | interleukin-33 receptor activity(GO:0002114) |
1.2 | 3.5 | GO:0050479 | glyceryl-ether monooxygenase activity(GO:0050479) |
1.1 | 3.3 | GO:0031726 | CCR1 chemokine receptor binding(GO:0031726) |
1.0 | 3.1 | GO:0016155 | formyltetrahydrofolate dehydrogenase activity(GO:0016155) |
1.0 | 4.9 | GO:0046980 | peptide antigen-transporting ATPase activity(GO:0015433) tapasin binding(GO:0046980) |
0.9 | 3.6 | GO:0031849 | olfactory receptor binding(GO:0031849) |
0.9 | 8.0 | GO:0003909 | DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910) |
0.8 | 9.3 | GO:0001730 | 2'-5'-oligoadenylate synthetase activity(GO:0001730) |
0.7 | 2.1 | GO:0019153 | protein-disulfide reductase (glutathione) activity(GO:0019153) |
0.7 | 6.6 | GO:0004886 | 9-cis retinoic acid receptor activity(GO:0004886) |
0.6 | 3.7 | GO:0016174 | NAD(P)H oxidase activity(GO:0016174) |
0.6 | 3.0 | GO:0004883 | glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051) |
0.5 | 1.6 | GO:0005110 | frizzled-2 binding(GO:0005110) |
0.5 | 5.2 | GO:0051434 | BH3 domain binding(GO:0051434) |
0.5 | 5.2 | GO:0004322 | ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724) |
0.5 | 1.5 | GO:0042015 | interleukin-20 binding(GO:0042015) |
0.5 | 2.0 | GO:0047710 | bis(5'-adenosyl)-triphosphatase activity(GO:0047710) |
0.5 | 16.9 | GO:0008009 | chemokine activity(GO:0008009) |
0.4 | 3.1 | GO:0016936 | galactoside binding(GO:0016936) |
0.4 | 1.2 | GO:0070890 | L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890) |
0.3 | 0.6 | GO:0046978 | TAP1 binding(GO:0046978) TAP2 binding(GO:0046979) |
0.3 | 1.1 | GO:0035276 | ethanol binding(GO:0035276) |
0.3 | 5.7 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
0.3 | 0.8 | GO:0001716 | L-amino-acid oxidase activity(GO:0001716) |
0.2 | 1.2 | GO:0038085 | vascular endothelial growth factor binding(GO:0038085) |
0.2 | 1.9 | GO:0031730 | CCR5 chemokine receptor binding(GO:0031730) |
0.2 | 2.9 | GO:0001206 | transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206) |
0.2 | 0.7 | GO:0047275 | glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275) |
0.1 | 1.3 | GO:0005138 | interleukin-6 receptor binding(GO:0005138) |
0.1 | 1.3 | GO:0039706 | co-receptor binding(GO:0039706) |
0.1 | 2.2 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
0.1 | 25.7 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
0.1 | 3.9 | GO:0043539 | protein serine/threonine kinase activator activity(GO:0043539) |
0.1 | 0.9 | GO:0038062 | protein tyrosine kinase collagen receptor activity(GO:0038062) |
0.1 | 2.1 | GO:0070628 | proteasome binding(GO:0070628) |
0.1 | 4.2 | GO:0043531 | ADP binding(GO:0043531) |
0.1 | 0.5 | GO:0005030 | neurotrophin receptor activity(GO:0005030) |
0.1 | 1.1 | GO:0017154 | semaphorin receptor activity(GO:0017154) |
0.1 | 0.5 | GO:0033142 | progesterone receptor binding(GO:0033142) |
0.1 | 2.0 | GO:0005521 | lamin binding(GO:0005521) |
0.1 | 0.3 | GO:0070052 | collagen V binding(GO:0070052) |
0.1 | 5.5 | GO:0003725 | double-stranded RNA binding(GO:0003725) |
0.1 | 19.0 | GO:0003924 | GTPase activity(GO:0003924) |
0.1 | 1.6 | GO:0046961 | proton-transporting ATPase activity, rotational mechanism(GO:0046961) |
0.1 | 6.9 | GO:0020037 | heme binding(GO:0020037) |
0.1 | 2.1 | GO:0071837 | HMG box domain binding(GO:0071837) |
0.0 | 0.5 | GO:0097200 | cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200) |
0.0 | 0.6 | GO:0051378 | serotonin binding(GO:0051378) |
0.0 | 0.2 | GO:0072542 | protein phosphatase activator activity(GO:0072542) |
0.0 | 9.1 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
0.0 | 1.8 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
0.0 | 2.7 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
0.0 | 4.9 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
0.0 | 0.1 | GO:0005146 | leukemia inhibitory factor receptor binding(GO:0005146) |
0.0 | 0.2 | GO:0001515 | opioid peptide activity(GO:0001515) |
0.0 | 2.7 | GO:0004197 | cysteine-type endopeptidase activity(GO:0004197) |
0.0 | 1.8 | GO:0032266 | phosphatidylinositol-3-phosphate binding(GO:0032266) |
0.0 | 2.1 | GO:0004520 | endodeoxyribonuclease activity(GO:0004520) |
0.0 | 2.6 | GO:0036459 | thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005) |
0.0 | 2.8 | GO:0042826 | histone deacetylase binding(GO:0042826) |
0.0 | 0.2 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
0.0 | 3.0 | GO:0004725 | protein tyrosine phosphatase activity(GO:0004725) |
0.0 | 0.9 | GO:0004864 | protein phosphatase inhibitor activity(GO:0004864) |
0.0 | 0.9 | GO:0050699 | WW domain binding(GO:0050699) |
0.0 | 6.3 | GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) |
0.0 | 0.4 | GO:0033613 | activating transcription factor binding(GO:0033613) |
0.0 | 1.0 | GO:0001102 | RNA polymerase II activating transcription factor binding(GO:0001102) |
0.0 | 2.7 | GO:0004984 | olfactory receptor activity(GO:0004984) |
0.0 | 0.3 | GO:0001530 | lipopolysaccharide binding(GO:0001530) |
0.0 | 0.5 | GO:0050681 | androgen receptor binding(GO:0050681) |
0.0 | 0.6 | GO:0030332 | cyclin binding(GO:0030332) |
0.0 | 0.6 | GO:0005044 | scavenger receptor activity(GO:0005044) |
0.0 | 0.2 | GO:1904264 | ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264) |
0.0 | 3.1 | GO:0001047 | core promoter binding(GO:0001047) |
0.0 | 1.9 | GO:0004386 | helicase activity(GO:0004386) |
0.0 | 1.0 | GO:0008276 | protein methyltransferase activity(GO:0008276) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 3.9 | ST TYPE I INTERFERON PATHWAY | Type I Interferon (alpha/beta IFN) Pathway |
0.2 | 4.6 | ST G ALPHA S PATHWAY | G alpha s Pathway |
0.2 | 15.9 | PID IL4 2PATHWAY | IL4-mediated signaling events |
0.2 | 11.8 | PID NFAT TFPATHWAY | Calcineurin-regulated NFAT-dependent transcription in lymphocytes |
0.1 | 6.6 | PID RETINOIC ACID PATHWAY | Retinoic acid receptors-mediated signaling |
0.1 | 5.8 | PID IL1 PATHWAY | IL1-mediated signaling events |
0.1 | 3.9 | PID IGF1 PATHWAY | IGF1 pathway |
0.1 | 1.7 | PID IL27 PATHWAY | IL27-mediated signaling events |
0.1 | 3.9 | PID CD8 TCR DOWNSTREAM PATHWAY | Downstream signaling in naïve CD8+ T cells |
0.1 | 1.8 | PID ERBB NETWORK PATHWAY | ErbB receptor signaling network |
0.1 | 6.2 | PID MYC REPRESS PATHWAY | Validated targets of C-MYC transcriptional repression |
0.1 | 5.2 | PID HIF1 TFPATHWAY | HIF-1-alpha transcription factor network |
0.1 | 5.3 | PID SMAD2 3NUCLEAR PATHWAY | Regulation of nuclear SMAD2/3 signaling |
0.1 | 12.5 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
0.0 | 2.3 | PID TELOMERASE PATHWAY | Regulation of Telomerase |
0.0 | 2.1 | PID RB 1PATHWAY | Regulation of retinoblastoma protein |
0.0 | 1.2 | PID CXCR3 PATHWAY | CXCR3-mediated signaling events |
0.0 | 2.0 | SIG PIP3 SIGNALING IN CARDIAC MYOCTES | Genes related to PIP3 signaling in cardiac myocytes |
0.0 | 1.2 | PID P38 ALPHA BETA DOWNSTREAM PATHWAY | Signaling mediated by p38-alpha and p38-beta |
0.0 | 0.8 | PID SHP2 PATHWAY | SHP2 signaling |
0.0 | 5.0 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
0.0 | 0.9 | PID AURORA A PATHWAY | Aurora A signaling |
0.0 | 0.5 | SA CASPASE CASCADE | Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade. |
0.0 | 2.8 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
0.0 | 1.0 | PID ECADHERIN STABILIZATION PATHWAY | Stabilization and expansion of the E-cadherin adherens junction |
0.0 | 0.7 | PID TRKR PATHWAY | Neurotrophic factor-mediated Trk receptor signaling |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.8 | 9.3 | REACTOME DEFENSINS | Genes involved in Defensins |
0.6 | 1.9 | REACTOME ENDOSOMAL VACUOLAR PATHWAY | Genes involved in Endosomal/Vacuolar pathway |
0.3 | 4.6 | REACTOME REGULATION OF COMPLEMENT CASCADE | Genes involved in Regulation of Complement cascade |
0.3 | 6.3 | REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC | Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC |
0.3 | 6.0 | REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY | Genes involved in TRAF3-dependent IRF activation pathway |
0.3 | 12.7 | REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
0.3 | 4.9 | REACTOME REGULATION OF IFNA SIGNALING | Genes involved in Regulation of IFNA signaling |
0.2 | 5.6 | REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI | Genes involved in RIP-mediated NFkB activation via DAI |
0.2 | 3.2 | REACTOME TRYPTOPHAN CATABOLISM | Genes involved in Tryptophan catabolism |
0.2 | 7.5 | REACTOME INTERFERON GAMMA SIGNALING | Genes involved in Interferon gamma signaling |
0.1 | 4.2 | REACTOME SULFUR AMINO ACID METABOLISM | Genes involved in Sulfur amino acid metabolism |
0.1 | 5.2 | REACTOME METAL ION SLC TRANSPORTERS | Genes involved in Metal ion SLC transporters |
0.1 | 5.3 | REACTOME IL1 SIGNALING | Genes involved in Interleukin-1 signaling |
0.1 | 9.6 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
0.1 | 2.7 | REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX | Genes involved in Degradation of the extracellular matrix |
0.1 | 1.2 | REACTOME PURINE CATABOLISM | Genes involved in Purine catabolism |
0.1 | 1.8 | REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION | Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) |
0.1 | 0.8 | REACTOME PD1 SIGNALING | Genes involved in PD-1 signaling |
0.1 | 1.8 | REACTOME SHC1 EVENTS IN ERBB4 SIGNALING | Genes involved in SHC1 events in ERBB4 signaling |
0.1 | 1.8 | REACTOME INSULIN RECEPTOR RECYCLING | Genes involved in Insulin receptor recycling |
0.1 | 0.6 | REACTOME SEROTONIN RECEPTORS | Genes involved in Serotonin receptors |
0.0 | 1.3 | REACTOME RIG I MDA5 MEDIATED INDUCTION OF IFN ALPHA BETA PATHWAYS | Genes involved in RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways |
0.0 | 1.1 | REACTOME OTHER SEMAPHORIN INTERACTIONS | Genes involved in Other semaphorin interactions |
0.0 | 1.1 | REACTOME EFFECTS OF PIP2 HYDROLYSIS | Genes involved in Effects of PIP2 hydrolysis |
0.0 | 2.7 | REACTOME MHC CLASS II ANTIGEN PRESENTATION | Genes involved in MHC class II antigen presentation |
0.0 | 1.2 | REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 | Genes involved in SCF-beta-TrCP mediated degradation of Emi1 |
0.0 | 0.3 | REACTOME TIE2 SIGNALING | Genes involved in Tie2 Signaling |
0.0 | 1.2 | REACTOME METABOLISM OF VITAMINS AND COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
0.0 | 0.5 | REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS | Genes involved in Caspase-mediated cleavage of cytoskeletal proteins |
0.0 | 0.5 | REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
0.0 | 1.2 | REACTOME DOWNSTREAM SIGNAL TRANSDUCTION | Genes involved in Downstream signal transduction |
0.0 | 2.1 | REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
0.0 | 0.1 | REACTOME PROLACTIN RECEPTOR SIGNALING | Genes involved in Prolactin receptor signaling |