avrg: GSE58827: Dynamics of the Mouse Liver
Gene Symbol | Gene ID | Gene Info |
---|---|---|
E2f2
|
ENSMUSG00000018983.9 | E2F transcription factor 2 |
E2f5
|
ENSMUSG00000027552.8 | E2F transcription factor 5 |
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
E2f2 | mm10_v2_chr4_+_136172367_136172395 | 0.96 | 1.0e-20 | Click! |
E2f5 | mm10_v2_chr3_+_14578609_14578687 | 0.46 | 4.3e-03 | Click! |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
25.1 | 75.3 | GO:0072488 | ammonium transmembrane transport(GO:0072488) |
15.7 | 110.0 | GO:1990086 | lens fiber cell apoptotic process(GO:1990086) |
14.8 | 147.6 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
10.9 | 21.7 | GO:0006272 | leading strand elongation(GO:0006272) |
10.1 | 30.3 | GO:0032877 | positive regulation of DNA endoreduplication(GO:0032877) |
9.7 | 106.9 | GO:0033314 | mitotic DNA replication checkpoint(GO:0033314) |
9.0 | 36.1 | GO:0007056 | spindle assembly involved in female meiosis(GO:0007056) |
9.0 | 44.9 | GO:0034421 | post-translational protein acetylation(GO:0034421) |
7.8 | 23.5 | GO:0045004 | DNA replication proofreading(GO:0045004) |
7.2 | 107.9 | GO:0010216 | maintenance of DNA methylation(GO:0010216) |
7.1 | 7.1 | GO:0010159 | specification of organ position(GO:0010159) |
6.1 | 36.4 | GO:0019371 | cyclooxygenase pathway(GO:0019371) |
5.8 | 57.9 | GO:1902969 | mitotic DNA replication(GO:1902969) |
5.2 | 31.1 | GO:0042276 | error-prone translesion synthesis(GO:0042276) |
5.2 | 5.2 | GO:0060821 | inactivation of X chromosome by DNA methylation(GO:0060821) |
4.5 | 18.0 | GO:0000076 | DNA replication checkpoint(GO:0000076) |
4.3 | 34.1 | GO:0051572 | negative regulation of histone H3-K4 methylation(GO:0051572) |
4.2 | 4.2 | GO:2000016 | negative regulation of determination of dorsal identity(GO:2000016) |
4.1 | 102.5 | GO:0006270 | DNA replication initiation(GO:0006270) |
3.9 | 3.9 | GO:0031990 | mRNA export from nucleus in response to heat stress(GO:0031990) |
3.8 | 69.1 | GO:0009263 | deoxyribonucleotide biosynthetic process(GO:0009263) |
3.8 | 34.1 | GO:0090166 | Golgi disassembly(GO:0090166) |
3.8 | 52.6 | GO:0033504 | floor plate development(GO:0033504) |
3.7 | 21.9 | GO:0019985 | translesion synthesis(GO:0019985) |
3.5 | 10.6 | GO:0045660 | positive regulation of neutrophil differentiation(GO:0045660) |
3.4 | 13.4 | GO:0046125 | pyrimidine deoxyribonucleoside metabolic process(GO:0046125) |
3.0 | 24.2 | GO:0090267 | positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) |
3.0 | 21.0 | GO:0042148 | strand invasion(GO:0042148) |
3.0 | 11.9 | GO:0044330 | canonical Wnt signaling pathway involved in positive regulation of wound healing(GO:0044330) lactic acid secretion(GO:0046722) regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096) |
2.7 | 31.8 | GO:0031936 | negative regulation of chromatin silencing(GO:0031936) |
2.6 | 7.8 | GO:0031660 | regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) |
2.5 | 10.2 | GO:0002025 | vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025) |
2.5 | 10.0 | GO:1904306 | response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109) positive regulation of gastro-intestinal system smooth muscle contraction(GO:1904306) |
2.5 | 39.7 | GO:0048304 | positive regulation of isotype switching to IgG isotypes(GO:0048304) |
2.4 | 24.5 | GO:0030206 | chondroitin sulfate biosynthetic process(GO:0030206) |
2.3 | 7.0 | GO:0099547 | regulation of translation at synapse, modulating synaptic transmission(GO:0099547) regulation of translation at postsynapse, modulating synaptic transmission(GO:0099578) positive regulation of intracellular transport of viral material(GO:1901254) |
2.3 | 6.8 | GO:0071707 | immunoglobulin heavy chain V-D-J recombination(GO:0071707) |
2.1 | 27.8 | GO:0051571 | positive regulation of histone H3-K4 methylation(GO:0051571) |
2.1 | 10.6 | GO:0033567 | DNA replication, Okazaki fragment processing(GO:0033567) DNA replication, removal of RNA primer(GO:0043137) |
2.1 | 6.2 | GO:1904975 | response to bleomycin(GO:1904975) cellular response to bleomycin(GO:1904976) |
2.0 | 7.9 | GO:0006297 | nucleotide-excision repair, DNA gap filling(GO:0006297) |
2.0 | 5.9 | GO:0006285 | base-excision repair, AP site formation(GO:0006285) |
1.9 | 19.5 | GO:0034379 | very-low-density lipoprotein particle assembly(GO:0034379) |
1.9 | 16.9 | GO:0021631 | optic nerve morphogenesis(GO:0021631) |
1.8 | 11.0 | GO:1903336 | endosome localization(GO:0032439) negative regulation of vacuolar transport(GO:1903336) |
1.8 | 14.2 | GO:2000232 | regulation of rRNA processing(GO:2000232) |
1.8 | 12.3 | GO:0070495 | regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495) |
1.6 | 61.7 | GO:0045662 | negative regulation of myoblast differentiation(GO:0045662) |
1.6 | 27.3 | GO:0001833 | inner cell mass cell proliferation(GO:0001833) |
1.6 | 20.7 | GO:0097067 | cellular response to thyroid hormone stimulus(GO:0097067) |
1.6 | 19.0 | GO:0033148 | positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148) |
1.6 | 11.0 | GO:0036337 | Fas signaling pathway(GO:0036337) |
1.5 | 15.2 | GO:0032876 | negative regulation of DNA endoreduplication(GO:0032876) |
1.5 | 4.4 | GO:0019065 | receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509) |
1.5 | 10.4 | GO:0097428 | protein maturation by iron-sulfur cluster transfer(GO:0097428) |
1.5 | 16.3 | GO:0000212 | meiotic spindle organization(GO:0000212) |
1.4 | 14.5 | GO:2000348 | regulation of CD40 signaling pathway(GO:2000348) |
1.4 | 16.8 | GO:0033280 | response to vitamin D(GO:0033280) |
1.3 | 3.8 | GO:0002270 | plasmacytoid dendritic cell activation(GO:0002270) |
1.3 | 3.8 | GO:0071947 | protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947) |
1.3 | 10.2 | GO:0070294 | renal sodium ion absorption(GO:0070294) |
1.3 | 3.8 | GO:0006597 | spermine biosynthetic process(GO:0006597) |
1.2 | 8.7 | GO:0061087 | positive regulation of histone H3-K27 methylation(GO:0061087) |
1.2 | 4.8 | GO:0061010 | gall bladder development(GO:0061010) |
1.1 | 15.6 | GO:0035845 | photoreceptor cell outer segment organization(GO:0035845) |
1.1 | 5.3 | GO:0071169 | establishment of protein localization to chromatin(GO:0071169) |
1.0 | 6.8 | GO:0045200 | establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200) |
1.0 | 10.6 | GO:0060923 | cardiac muscle cell fate commitment(GO:0060923) |
1.0 | 4.8 | GO:0034770 | histone H4-K20 methylation(GO:0034770) histone H4-K20 trimethylation(GO:0034773) |
0.9 | 8.3 | GO:2000980 | regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980) |
0.9 | 22.2 | GO:1902751 | positive regulation of cell cycle G2/M phase transition(GO:1902751) |
0.9 | 75.6 | GO:0006342 | chromatin silencing(GO:0006342) |
0.8 | 2.5 | GO:1903632 | positive regulation of aminoacyl-tRNA ligase activity(GO:1903632) |
0.8 | 10.0 | GO:0051573 | negative regulation of histone H3-K9 methylation(GO:0051573) |
0.8 | 6.4 | GO:0014043 | negative regulation of neuron maturation(GO:0014043) |
0.8 | 3.8 | GO:0090080 | positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080) |
0.8 | 4.5 | GO:2001032 | regulation of double-strand break repair via nonhomologous end joining(GO:2001032) |
0.7 | 24.7 | GO:0006284 | base-excision repair(GO:0006284) |
0.7 | 7.1 | GO:0070236 | negative regulation of activation-induced cell death of T cells(GO:0070236) |
0.7 | 6.9 | GO:0051026 | chiasma assembly(GO:0051026) |
0.7 | 6.2 | GO:0010457 | centriole-centriole cohesion(GO:0010457) |
0.7 | 4.1 | GO:2000346 | negative regulation of hepatocyte proliferation(GO:2000346) |
0.6 | 15.7 | GO:0040034 | regulation of development, heterochronic(GO:0040034) |
0.6 | 4.4 | GO:0098532 | histone H3-K27 trimethylation(GO:0098532) |
0.6 | 8.0 | GO:0007343 | egg activation(GO:0007343) |
0.6 | 2.4 | GO:0010724 | regulation of definitive erythrocyte differentiation(GO:0010724) |
0.6 | 2.9 | GO:0007089 | traversing start control point of mitotic cell cycle(GO:0007089) |
0.6 | 3.5 | GO:0016446 | somatic hypermutation of immunoglobulin genes(GO:0016446) |
0.6 | 4.0 | GO:0033600 | negative regulation of mammary gland epithelial cell proliferation(GO:0033600) regulation of branching involved in mammary gland duct morphogenesis(GO:0060762) |
0.6 | 2.3 | GO:1901594 | detection of temperature stimulus involved in thermoception(GO:0050960) response to capsazepine(GO:1901594) |
0.6 | 3.3 | GO:0000722 | telomere maintenance via recombination(GO:0000722) |
0.5 | 1.6 | GO:0043987 | histone H3-S10 phosphorylation(GO:0043987) histone H3-S28 phosphorylation(GO:0043988) |
0.5 | 1.6 | GO:0060382 | release from viral latency(GO:0019046) regulation of DNA strand elongation(GO:0060382) |
0.5 | 1.5 | GO:0060720 | spongiotrophoblast cell proliferation(GO:0060720) cell proliferation involved in embryonic placenta development(GO:0060722) |
0.5 | 26.8 | GO:0008156 | negative regulation of DNA replication(GO:0008156) |
0.5 | 35.7 | GO:0030512 | negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) |
0.5 | 4.8 | GO:0006924 | activation-induced cell death of T cells(GO:0006924) |
0.5 | 3.8 | GO:0000395 | mRNA 5'-splice site recognition(GO:0000395) |
0.5 | 13.4 | GO:0000413 | protein peptidyl-prolyl isomerization(GO:0000413) |
0.5 | 1.4 | GO:0019389 | glucuronoside metabolic process(GO:0019389) |
0.5 | 1.8 | GO:0003349 | epicardium-derived cardiac endothelial cell differentiation(GO:0003349) |
0.4 | 8.0 | GO:0009303 | rRNA transcription(GO:0009303) |
0.4 | 9.9 | GO:0048026 | positive regulation of mRNA splicing, via spliceosome(GO:0048026) |
0.4 | 2.6 | GO:0006020 | inositol metabolic process(GO:0006020) |
0.4 | 1.4 | GO:0032789 | saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789) |
0.4 | 2.1 | GO:0015727 | lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879) |
0.3 | 18.8 | GO:0043550 | regulation of lipid kinase activity(GO:0043550) |
0.3 | 10.4 | GO:0007099 | centriole replication(GO:0007099) |
0.3 | 4.8 | GO:0035970 | peptidyl-threonine dephosphorylation(GO:0035970) |
0.3 | 2.4 | GO:0007000 | nucleolus organization(GO:0007000) |
0.3 | 0.6 | GO:0071557 | histone H3-K27 demethylation(GO:0071557) |
0.3 | 3.2 | GO:1903715 | regulation of aerobic respiration(GO:1903715) |
0.3 | 11.4 | GO:0000387 | spliceosomal snRNP assembly(GO:0000387) |
0.3 | 2.9 | GO:0046543 | development of secondary female sexual characteristics(GO:0046543) |
0.3 | 5.5 | GO:0044818 | mitotic G2/M transition checkpoint(GO:0044818) |
0.3 | 0.8 | GO:0070682 | proteasome regulatory particle assembly(GO:0070682) |
0.3 | 9.4 | GO:0046854 | phosphatidylinositol phosphorylation(GO:0046854) |
0.2 | 0.5 | GO:1904328 | regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764) |
0.2 | 1.9 | GO:0031087 | deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087) |
0.2 | 0.9 | GO:1903984 | positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984) |
0.2 | 1.8 | GO:0035562 | negative regulation of chromatin binding(GO:0035562) |
0.2 | 23.7 | GO:0006334 | nucleosome assembly(GO:0006334) |
0.2 | 1.1 | GO:0070535 | histone H2A K63-linked ubiquitination(GO:0070535) |
0.2 | 1.9 | GO:1900364 | negative regulation of mRNA polyadenylation(GO:1900364) |
0.2 | 4.9 | GO:0034453 | microtubule anchoring(GO:0034453) |
0.2 | 12.5 | GO:0032781 | positive regulation of ATPase activity(GO:0032781) |
0.2 | 1.4 | GO:0006685 | sphingomyelin catabolic process(GO:0006685) |
0.2 | 1.9 | GO:0048386 | positive regulation of retinoic acid receptor signaling pathway(GO:0048386) |
0.2 | 0.8 | GO:0043983 | histone H4-K12 acetylation(GO:0043983) |
0.2 | 1.2 | GO:0072697 | protein localization to cell cortex(GO:0072697) |
0.2 | 16.4 | GO:0035308 | negative regulation of protein dephosphorylation(GO:0035308) |
0.2 | 6.9 | GO:0061003 | positive regulation of dendritic spine morphogenesis(GO:0061003) |
0.1 | 3.1 | GO:0007130 | synaptonemal complex assembly(GO:0007130) |
0.1 | 5.4 | GO:0000381 | regulation of alternative mRNA splicing, via spliceosome(GO:0000381) |
0.1 | 3.2 | GO:0040037 | negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037) |
0.1 | 0.5 | GO:0010286 | heat acclimation(GO:0010286) |
0.1 | 1.2 | GO:0072401 | signal transduction involved in cell cycle checkpoint(GO:0072395) signal transduction involved in DNA integrity checkpoint(GO:0072401) signal transduction involved in DNA damage checkpoint(GO:0072422) |
0.1 | 6.1 | GO:0043966 | histone H3 acetylation(GO:0043966) |
0.1 | 2.2 | GO:0032098 | regulation of appetite(GO:0032098) |
0.1 | 1.1 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
0.1 | 0.8 | GO:0010793 | regulation of mRNA export from nucleus(GO:0010793) regulation of ribonucleoprotein complex localization(GO:2000197) |
0.1 | 2.9 | GO:0001921 | positive regulation of receptor recycling(GO:0001921) |
0.1 | 2.1 | GO:0071260 | cellular response to mechanical stimulus(GO:0071260) |
0.1 | 1.1 | GO:0018095 | protein polyglutamylation(GO:0018095) |
0.1 | 1.5 | GO:0000291 | nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) |
0.1 | 5.5 | GO:0019228 | neuronal action potential(GO:0019228) |
0.1 | 0.7 | GO:1901844 | regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844) |
0.1 | 3.1 | GO:0048520 | positive regulation of behavior(GO:0048520) |
0.1 | 0.2 | GO:0036228 | protein targeting to nuclear inner membrane(GO:0036228) |
0.1 | 9.2 | GO:0016579 | protein deubiquitination(GO:0016579) |
0.1 | 1.7 | GO:0021511 | spinal cord patterning(GO:0021511) |
0.1 | 3.4 | GO:0016925 | protein sumoylation(GO:0016925) |
0.1 | 3.2 | GO:0045773 | positive regulation of axon extension(GO:0045773) |
0.1 | 1.0 | GO:0042407 | cristae formation(GO:0042407) |
0.1 | 7.1 | GO:0030010 | establishment of cell polarity(GO:0030010) |
0.1 | 3.2 | GO:0000086 | G2/M transition of mitotic cell cycle(GO:0000086) |
0.1 | 2.1 | GO:0034314 | Arp2/3 complex-mediated actin nucleation(GO:0034314) |
0.1 | 0.7 | GO:0001731 | formation of translation preinitiation complex(GO:0001731) |
0.1 | 15.1 | GO:0007018 | microtubule-based movement(GO:0007018) |
0.1 | 0.7 | GO:1904251 | regulation of bile acid metabolic process(GO:1904251) |
0.0 | 3.6 | GO:0048477 | oogenesis(GO:0048477) |
0.0 | 3.2 | GO:0051225 | spindle assembly(GO:0051225) |
0.0 | 3.0 | GO:0035914 | skeletal muscle cell differentiation(GO:0035914) |
0.0 | 0.6 | GO:0046827 | positive regulation of protein export from nucleus(GO:0046827) |
0.0 | 1.9 | GO:0031076 | embryonic camera-type eye development(GO:0031076) |
0.0 | 0.2 | GO:0010587 | miRNA catabolic process(GO:0010587) |
0.0 | 1.2 | GO:0001578 | microtubule bundle formation(GO:0001578) |
0.0 | 0.5 | GO:0048148 | behavioral response to cocaine(GO:0048148) |
0.0 | 2.6 | GO:0006637 | acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383) |
0.0 | 0.5 | GO:0014051 | gamma-aminobutyric acid secretion(GO:0014051) |
0.0 | 0.3 | GO:0032968 | positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968) |
0.0 | 0.1 | GO:0060056 | mammary gland involution(GO:0060056) |
0.0 | 4.9 | GO:0048511 | rhythmic process(GO:0048511) |
0.0 | 0.5 | GO:0060612 | adipose tissue development(GO:0060612) |
0.0 | 0.9 | GO:0021510 | spinal cord development(GO:0021510) |
0.0 | 0.3 | GO:0000470 | maturation of LSU-rRNA(GO:0000470) |
0.0 | 1.7 | GO:0002244 | hematopoietic progenitor cell differentiation(GO:0002244) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
13.8 | 69.1 | GO:0005971 | ribonucleoside-diphosphate reductase complex(GO:0005971) |
12.1 | 182.2 | GO:0042555 | MCM complex(GO:0042555) |
8.8 | 26.4 | GO:0000811 | GINS complex(GO:0000811) |
7.1 | 35.4 | GO:0008622 | epsilon DNA polymerase complex(GO:0008622) |
5.9 | 29.4 | GO:0035189 | Rb-E2F complex(GO:0035189) |
5.9 | 29.3 | GO:0031298 | replication fork protection complex(GO:0031298) |
5.0 | 44.9 | GO:0031390 | Ctf18 RFC-like complex(GO:0031390) |
4.7 | 14.1 | GO:0043625 | delta DNA polymerase complex(GO:0043625) |
4.0 | 12.1 | GO:0097135 | cyclin E2-CDK2 complex(GO:0097135) |
3.7 | 18.4 | GO:0005658 | alpha DNA polymerase:primase complex(GO:0005658) |
2.8 | 14.2 | GO:0001651 | dense fibrillar component(GO:0001651) |
2.8 | 155.2 | GO:0005657 | replication fork(GO:0005657) |
2.6 | 10.5 | GO:0097129 | cyclin D2-CDK4 complex(GO:0097129) |
2.6 | 10.4 | GO:0032389 | MutLalpha complex(GO:0032389) |
2.1 | 18.7 | GO:0030991 | intraciliary transport particle A(GO:0030991) |
2.1 | 20.8 | GO:0000796 | condensin complex(GO:0000796) |
2.0 | 10.0 | GO:0033553 | rDNA heterochromatin(GO:0033553) |
1.9 | 5.6 | GO:0035061 | interchromatin granule(GO:0035061) |
1.8 | 11.0 | GO:0097443 | sorting endosome(GO:0097443) |
1.8 | 7.0 | GO:0019034 | viral replication complex(GO:0019034) dendritic filopodium(GO:1902737) |
1.8 | 5.3 | GO:0031933 | telomeric heterochromatin(GO:0031933) |
1.7 | 8.6 | GO:0034715 | pICln-Sm protein complex(GO:0034715) |
1.6 | 21.9 | GO:0031464 | Cul4A-RING E3 ubiquitin ligase complex(GO:0031464) |
1.4 | 8.6 | GO:0034991 | nuclear meiotic cohesin complex(GO:0034991) |
1.3 | 19.8 | GO:0031618 | nuclear pericentric heterochromatin(GO:0031618) |
1.3 | 7.6 | GO:0070776 | H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776) |
1.2 | 7.2 | GO:0098536 | deuterosome(GO:0098536) |
1.1 | 7.8 | GO:0005638 | lamin filament(GO:0005638) |
1.0 | 5.2 | GO:0001740 | Barr body(GO:0001740) |
1.0 | 53.3 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
0.9 | 2.8 | GO:0005683 | U7 snRNP(GO:0005683) |
0.9 | 9.8 | GO:0043240 | Fanconi anaemia nuclear complex(GO:0043240) |
0.8 | 21.6 | GO:0035861 | site of double-strand break(GO:0035861) |
0.8 | 19.8 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
0.7 | 6.4 | GO:0016012 | sarcoglycan complex(GO:0016012) |
0.7 | 120.3 | GO:0090575 | RNA polymerase II transcription factor complex(GO:0090575) |
0.7 | 5.9 | GO:0000243 | commitment complex(GO:0000243) |
0.6 | 12.9 | GO:0070822 | Sin3-type complex(GO:0070822) |
0.6 | 40.3 | GO:0044815 | nucleosome(GO:0000786) DNA packaging complex(GO:0044815) |
0.6 | 9.4 | GO:0032580 | Golgi cisterna membrane(GO:0032580) |
0.6 | 7.6 | GO:0001673 | male germ cell nucleus(GO:0001673) |
0.5 | 34.1 | GO:0005871 | kinesin complex(GO:0005871) |
0.5 | 8.0 | GO:0005736 | DNA-directed RNA polymerase I complex(GO:0005736) |
0.5 | 1.5 | GO:0031251 | PAN complex(GO:0031251) |
0.5 | 52.1 | GO:0005814 | centriole(GO:0005814) |
0.5 | 2.7 | GO:0044530 | supraspliceosomal complex(GO:0044530) |
0.4 | 11.9 | GO:0005719 | nuclear euchromatin(GO:0005719) |
0.4 | 1.2 | GO:0034673 | inhibin-betaglycan-ActRII complex(GO:0034673) |
0.4 | 0.8 | GO:0008540 | proteasome regulatory particle, base subcomplex(GO:0008540) |
0.4 | 3.2 | GO:0070652 | HAUS complex(GO:0070652) |
0.4 | 33.6 | GO:0005776 | autophagosome(GO:0005776) |
0.4 | 10.7 | GO:0051233 | spindle midzone(GO:0051233) |
0.4 | 6.7 | GO:0032433 | filopodium tip(GO:0032433) |
0.3 | 3.1 | GO:0000801 | central element(GO:0000801) |
0.3 | 35.5 | GO:0000781 | chromosome, telomeric region(GO:0000781) |
0.3 | 20.1 | GO:0072686 | mitotic spindle(GO:0072686) |
0.3 | 4.4 | GO:0030122 | AP-2 adaptor complex(GO:0030122) |
0.3 | 29.5 | GO:0016363 | nuclear matrix(GO:0016363) |
0.3 | 1.2 | GO:0034709 | methylosome(GO:0034709) |
0.3 | 2.9 | GO:0031080 | nuclear pore outer ring(GO:0031080) |
0.3 | 1.4 | GO:0000791 | euchromatin(GO:0000791) |
0.3 | 3.4 | GO:0044232 | organelle membrane contact site(GO:0044232) |
0.3 | 4.6 | GO:0032993 | protein-DNA complex(GO:0032993) |
0.2 | 63.1 | GO:0005667 | transcription factor complex(GO:0005667) |
0.2 | 3.0 | GO:0005862 | muscle thin filament tropomyosin(GO:0005862) |
0.2 | 30.0 | GO:0005819 | spindle(GO:0005819) |
0.2 | 150.0 | GO:0005694 | chromosome(GO:0005694) |
0.2 | 15.2 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
0.2 | 11.0 | GO:0016605 | PML body(GO:0016605) |
0.2 | 2.1 | GO:0005885 | Arp2/3 protein complex(GO:0005885) |
0.2 | 8.1 | GO:0032809 | neuronal cell body membrane(GO:0032809) |
0.2 | 0.5 | GO:0001652 | granular component(GO:0001652) |
0.2 | 2.5 | GO:0017101 | aminoacyl-tRNA synthetase multienzyme complex(GO:0017101) |
0.1 | 1.4 | GO:1904115 | axon cytoplasm(GO:1904115) |
0.1 | 3.8 | GO:0035145 | exon-exon junction complex(GO:0035145) |
0.1 | 7.1 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
0.1 | 1.1 | GO:0071565 | nBAF complex(GO:0071565) |
0.1 | 1.9 | GO:0097470 | ribbon synapse(GO:0097470) |
0.1 | 2.9 | GO:0030665 | clathrin-coated vesicle membrane(GO:0030665) |
0.1 | 1.0 | GO:0061617 | MICOS complex(GO:0061617) |
0.1 | 2.2 | GO:0034451 | centriolar satellite(GO:0034451) |
0.1 | 1.0 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
0.1 | 2.9 | GO:0043204 | perikaryon(GO:0043204) |
0.1 | 6.8 | GO:0016328 | lateral plasma membrane(GO:0016328) |
0.1 | 10.5 | GO:0001669 | acrosomal vesicle(GO:0001669) |
0.1 | 0.6 | GO:0044666 | MLL3/4 complex(GO:0044666) |
0.1 | 2.4 | GO:0015030 | Cajal body(GO:0015030) |
0.1 | 1.3 | GO:0043194 | axon initial segment(GO:0043194) |
0.1 | 3.3 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
0.1 | 28.3 | GO:0048471 | perinuclear region of cytoplasm(GO:0048471) |
0.1 | 0.6 | GO:0097440 | apical dendrite(GO:0097440) |
0.1 | 168.5 | GO:0005829 | cytosol(GO:0005829) |
0.0 | 0.2 | GO:0044611 | nuclear pore inner ring(GO:0044611) |
0.0 | 1.4 | GO:0005844 | polysome(GO:0005844) |
0.0 | 56.1 | GO:0005887 | integral component of plasma membrane(GO:0005887) |
0.0 | 12.0 | GO:0005730 | nucleolus(GO:0005730) |
0.0 | 0.5 | GO:0005905 | clathrin-coated pit(GO:0005905) |
0.0 | 2.4 | GO:0031965 | nuclear membrane(GO:0031965) |
0.0 | 0.7 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
0.0 | 63.2 | GO:0005634 | nucleus(GO:0005634) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
16.5 | 99.3 | GO:0010997 | anaphase-promoting complex binding(GO:0010997) |
13.8 | 69.1 | GO:0016728 | ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731) |
13.6 | 81.9 | GO:0031493 | nucleosomal histone binding(GO:0031493) |
7.2 | 28.9 | GO:0071987 | WD40-repeat domain binding(GO:0071987) |
5.9 | 41.5 | GO:0000150 | recombinase activity(GO:0000150) |
5.7 | 79.7 | GO:0003688 | DNA replication origin binding(GO:0003688) |
5.6 | 22.4 | GO:0048256 | flap endonuclease activity(GO:0048256) |
5.2 | 36.4 | GO:0017050 | sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050) |
4.1 | 44.9 | GO:0033170 | DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170) |
4.0 | 24.2 | GO:0008821 | crossover junction endodeoxyribonuclease activity(GO:0008821) |
4.0 | 36.1 | GO:1990948 | ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948) |
3.4 | 13.4 | GO:0019136 | deoxynucleoside kinase activity(GO:0019136) |
3.1 | 9.4 | GO:0050510 | N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510) |
3.1 | 24.9 | GO:0003886 | DNA (cytosine-5-)-methyltransferase activity(GO:0003886) |
3.1 | 15.3 | GO:0000405 | bubble DNA binding(GO:0000405) |
3.0 | 15.1 | GO:0034481 | chondroitin sulfotransferase activity(GO:0034481) |
3.0 | 18.0 | GO:0044547 | DNA topoisomerase binding(GO:0044547) |
2.7 | 8.2 | GO:0030337 | DNA polymerase processivity factor activity(GO:0030337) |
2.6 | 121.8 | GO:0003678 | DNA helicase activity(GO:0003678) |
2.6 | 75.3 | GO:0008519 | ammonium transmembrane transporter activity(GO:0008519) |
2.5 | 10.2 | GO:0031711 | beta-adrenergic receptor activity(GO:0004939) bradykinin receptor binding(GO:0031711) |
2.4 | 67.8 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
2.4 | 16.9 | GO:0005005 | transmembrane-ephrin receptor activity(GO:0005005) |
2.2 | 6.7 | GO:0030350 | iron-responsive element binding(GO:0030350) |
2.2 | 6.5 | GO:0035402 | histone kinase activity (H3-T11 specific)(GO:0035402) |
2.0 | 36.8 | GO:0008353 | RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353) |
2.0 | 10.0 | GO:0046974 | histone methyltransferase activity (H3-K9 specific)(GO:0046974) |
2.0 | 7.9 | GO:0004741 | [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741) |
1.9 | 17.3 | GO:1990446 | U1 snRNP binding(GO:1990446) |
1.7 | 13.9 | GO:0032404 | mismatch repair complex binding(GO:0032404) |
1.7 | 12.0 | GO:0046976 | histone methyltransferase activity (H3-K27 specific)(GO:0046976) |
1.6 | 11.0 | GO:0032184 | SUMO polymer binding(GO:0032184) |
1.5 | 5.9 | GO:0004844 | uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506) |
1.3 | 3.8 | GO:0000402 | open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402) |
1.2 | 4.7 | GO:0036033 | mediator complex binding(GO:0036033) |
1.2 | 7.0 | GO:0033592 | RNA strand annealing activity(GO:0033592) |
1.2 | 10.5 | GO:0003910 | DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910) |
1.2 | 36.0 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
1.1 | 10.0 | GO:0004716 | receptor signaling protein tyrosine kinase activity(GO:0004716) |
1.0 | 9.3 | GO:0043047 | single-stranded telomeric DNA binding(GO:0043047) G-rich strand telomeric DNA binding(GO:0098505) |
0.9 | 3.8 | GO:0004566 | beta-glucuronidase activity(GO:0004566) |
0.8 | 9.1 | GO:1990226 | histone methyltransferase binding(GO:1990226) |
0.8 | 2.4 | GO:0070139 | ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139) |
0.8 | 20.0 | GO:0070182 | DNA polymerase binding(GO:0070182) |
0.7 | 5.8 | GO:0004865 | protein serine/threonine phosphatase inhibitor activity(GO:0004865) |
0.7 | 1.4 | GO:0004724 | magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724) |
0.7 | 6.3 | GO:0043024 | ribosomal small subunit binding(GO:0043024) |
0.6 | 1.8 | GO:0032564 | adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564) |
0.6 | 18.3 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
0.6 | 156.2 | GO:0001047 | core promoter binding(GO:0001047) |
0.5 | 32.6 | GO:0043425 | bHLH transcription factor binding(GO:0043425) |
0.5 | 28.5 | GO:0070491 | repressing transcription factor binding(GO:0070491) |
0.5 | 1.4 | GO:0016262 | protein N-acetylglucosaminyltransferase activity(GO:0016262) |
0.5 | 3.8 | GO:1990380 | Lys48-specific deubiquitinase activity(GO:1990380) |
0.5 | 6.5 | GO:0008327 | methyl-CpG binding(GO:0008327) |
0.4 | 15.7 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
0.4 | 6.3 | GO:0031386 | protein tag(GO:0031386) |
0.4 | 7.1 | GO:0071837 | HMG box domain binding(GO:0071837) |
0.4 | 7.7 | GO:0005528 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
0.4 | 2.3 | GO:0097603 | temperature-gated ion channel activity(GO:0097603) |
0.4 | 40.0 | GO:0001085 | RNA polymerase II transcription factor binding(GO:0001085) |
0.3 | 34.1 | GO:0003777 | microtubule motor activity(GO:0003777) |
0.3 | 4.9 | GO:0017134 | fibroblast growth factor binding(GO:0017134) |
0.3 | 2.1 | GO:0015129 | lactate transmembrane transporter activity(GO:0015129) |
0.3 | 1.1 | GO:0072345 | NAADP-sensitive calcium-release channel activity(GO:0072345) |
0.3 | 18.4 | GO:0004843 | thiol-dependent ubiquitin-specific protease activity(GO:0004843) |
0.3 | 30.9 | GO:0051087 | chaperone binding(GO:0051087) |
0.3 | 1.9 | GO:0030267 | hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267) |
0.3 | 2.1 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
0.3 | 9.2 | GO:0000062 | fatty-acyl-CoA binding(GO:0000062) |
0.3 | 5.7 | GO:0008432 | JUN kinase binding(GO:0008432) |
0.2 | 5.7 | GO:0003755 | peptidyl-prolyl cis-trans isomerase activity(GO:0003755) |
0.2 | 19.1 | GO:0004197 | cysteine-type endopeptidase activity(GO:0004197) |
0.2 | 25.6 | GO:0004386 | helicase activity(GO:0004386) |
0.2 | 38.6 | GO:0042393 | histone binding(GO:0042393) |
0.2 | 0.7 | GO:0017150 | tRNA dihydrouridine synthase activity(GO:0017150) |
0.2 | 5.1 | GO:0004407 | histone deacetylase activity(GO:0004407) |
0.2 | 0.2 | GO:0009008 | DNA-methyltransferase activity(GO:0009008) |
0.2 | 1.0 | GO:0051425 | PTB domain binding(GO:0051425) |
0.2 | 9.1 | GO:0050699 | WW domain binding(GO:0050699) |
0.2 | 4.6 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
0.2 | 2.4 | GO:0031996 | thioesterase binding(GO:0031996) |
0.2 | 10.4 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
0.2 | 1.4 | GO:0001055 | RNA polymerase II activity(GO:0001055) |
0.2 | 0.6 | GO:0071558 | histone demethylase activity (H3-K27 specific)(GO:0071558) |
0.2 | 4.8 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
0.2 | 4.1 | GO:0047617 | acyl-CoA hydrolase activity(GO:0047617) |
0.2 | 1.4 | GO:0004767 | sphingomyelin phosphodiesterase activity(GO:0004767) |
0.1 | 0.7 | GO:0004594 | pantothenate kinase activity(GO:0004594) |
0.1 | 1.2 | GO:0005114 | type II transforming growth factor beta receptor binding(GO:0005114) |
0.1 | 6.6 | GO:0048487 | beta-tubulin binding(GO:0048487) |
0.1 | 7.8 | GO:0001540 | beta-amyloid binding(GO:0001540) |
0.1 | 28.8 | GO:0001227 | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227) |
0.1 | 1.1 | GO:0070739 | protein-glutamic acid ligase activity(GO:0070739) |
0.1 | 40.6 | GO:0005096 | GTPase activator activity(GO:0005096) |
0.1 | 4.5 | GO:0031369 | translation initiation factor binding(GO:0031369) |
0.1 | 2.9 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
0.1 | 1.4 | GO:0070492 | oligosaccharide binding(GO:0070492) |
0.1 | 2.7 | GO:0097602 | cullin family protein binding(GO:0097602) |
0.1 | 3.2 | GO:0030332 | cyclin binding(GO:0030332) |
0.1 | 3.3 | GO:0003697 | single-stranded DNA binding(GO:0003697) |
0.1 | 2.2 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
0.1 | 1.9 | GO:0003756 | protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864) |
0.1 | 1.2 | GO:0032794 | GTPase activating protein binding(GO:0032794) |
0.1 | 48.9 | GO:0046982 | protein heterodimerization activity(GO:0046982) |
0.1 | 5.3 | GO:0005080 | protein kinase C binding(GO:0005080) |
0.1 | 1.5 | GO:0004535 | poly(A)-specific ribonuclease activity(GO:0004535) |
0.1 | 1.3 | GO:0031402 | sodium ion binding(GO:0031402) |
0.1 | 1.0 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
0.1 | 9.3 | GO:0042626 | ATPase activity, coupled to transmembrane movement of substances(GO:0042626) |
0.1 | 0.5 | GO:0001135 | transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135) |
0.1 | 2.6 | GO:0005160 | transforming growth factor beta receptor binding(GO:0005160) |
0.1 | 4.1 | GO:0015459 | potassium channel regulator activity(GO:0015459) |
0.1 | 0.2 | GO:0010484 | H3 histone acetyltransferase activity(GO:0010484) |
0.1 | 3.8 | GO:0016765 | transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765) |
0.0 | 4.2 | GO:0016779 | nucleotidyltransferase activity(GO:0016779) |
0.0 | 12.6 | GO:0061630 | ubiquitin protein ligase activity(GO:0061630) |
0.0 | 1.5 | GO:0017091 | AU-rich element binding(GO:0017091) |
0.0 | 0.2 | GO:0050265 | RNA uridylyltransferase activity(GO:0050265) |
0.0 | 0.6 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
0.0 | 1.2 | GO:0036002 | pre-mRNA binding(GO:0036002) |
0.0 | 0.8 | GO:0031593 | polyubiquitin binding(GO:0031593) |
0.0 | 2.8 | GO:0003714 | transcription corepressor activity(GO:0003714) |
0.0 | 5.1 | GO:0035091 | phosphatidylinositol binding(GO:0035091) |
0.0 | 10.5 | GO:0008270 | zinc ion binding(GO:0008270) |
0.0 | 1.6 | GO:0051219 | phosphoprotein binding(GO:0051219) |
0.0 | 1.9 | GO:0008047 | enzyme activator activity(GO:0008047) |
0.0 | 0.5 | GO:0002039 | p53 binding(GO:0002039) |
0.0 | 1.5 | GO:0008565 | protein transporter activity(GO:0008565) |
0.0 | 1.4 | GO:0004553 | hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553) |
0.0 | 0.2 | GO:0017056 | structural constituent of nuclear pore(GO:0017056) |
0.0 | 0.7 | GO:0051117 | ATPase binding(GO:0051117) |
0.0 | 11.1 | GO:0005524 | ATP binding(GO:0005524) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
8.4 | 75.9 | SA G2 AND M PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
8.3 | 133.6 | SA REG CASCADE OF CYCLIN EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
6.0 | 271.2 | PID ATR PATHWAY | ATR signaling pathway |
1.9 | 158.5 | PID E2F PATHWAY | E2F transcription factor network |
1.5 | 52.6 | PID HEDGEHOG 2PATHWAY | Signaling events mediated by the Hedgehog family |
1.3 | 36.4 | PID S1P S1P1 PATHWAY | S1P1 pathway |
1.0 | 26.8 | PID FOXM1 PATHWAY | FOXM1 transcription factor network |
1.0 | 48.5 | PID PLK1 PATHWAY | PLK1 signaling events |
0.9 | 95.7 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
0.9 | 11.0 | SA PROGRAMMED CELL DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
0.9 | 12.8 | ST JAK STAT PATHWAY | Jak-STAT Pathway |
0.7 | 21.0 | PID FANCONI PATHWAY | Fanconi anemia pathway |
0.7 | 27.8 | PID IL2 PI3K PATHWAY | IL2 signaling events mediated by PI3K |
0.5 | 8.2 | PID BARD1 PATHWAY | BARD1 signaling events |
0.4 | 28.8 | PID RB 1PATHWAY | Regulation of retinoblastoma protein |
0.4 | 12.3 | PID AURORA B PATHWAY | Aurora B signaling |
0.4 | 10.2 | PID SYNDECAN 2 PATHWAY | Syndecan-2-mediated signaling events |
0.3 | 29.9 | PID CMYB PATHWAY | C-MYB transcription factor network |
0.3 | 13.2 | PID CDC42 REG PATHWAY | Regulation of CDC42 activity |
0.2 | 6.7 | PID EPHRINB REV PATHWAY | Ephrin B reverse signaling |
0.1 | 3.1 | ST TUMOR NECROSIS FACTOR PATHWAY | Tumor Necrosis Factor Pathway. |
0.1 | 3.8 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
0.1 | 7.8 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
0.1 | 7.6 | PID ARF6 TRAFFICKING PATHWAY | Arf6 trafficking events |
0.1 | 3.9 | PID MAPK TRK PATHWAY | Trk receptor signaling mediated by the MAPK pathway |
0.1 | 4.1 | PID ILK PATHWAY | Integrin-linked kinase signaling |
0.1 | 4.4 | PID ERBB1 INTERNALIZATION PATHWAY | Internalization of ErbB1 |
0.1 | 6.7 | PID HIF1 TFPATHWAY | HIF-1-alpha transcription factor network |
0.1 | 7.7 | PID REG GR PATHWAY | Glucocorticoid receptor regulatory network |
0.1 | 1.8 | PID HDAC CLASSIII PATHWAY | Signaling events mediated by HDAC Class III |
0.1 | 3.2 | PID ERBB4 PATHWAY | ErbB4 signaling events |
0.1 | 3.3 | PID P53 REGULATION PATHWAY | p53 pathway |
0.1 | 2.4 | PID AR TF PATHWAY | Regulation of Androgen receptor activity |
0.1 | 2.1 | PID RAC1 PATHWAY | RAC1 signaling pathway |
0.0 | 1.5 | PID TNF PATHWAY | TNF receptor signaling pathway |
0.0 | 2.4 | SIG PIP3 SIGNALING IN CARDIAC MYOCTES | Genes related to PIP3 signaling in cardiac myocytes |
0.0 | 1.9 | PID P73PATHWAY | p73 transcription factor network |
0.0 | 1.0 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
0.0 | 1.5 | PID SMAD2 3NUCLEAR PATHWAY | Regulation of nuclear SMAD2/3 signaling |
0.0 | 0.5 | PID IL4 2PATHWAY | IL4-mediated signaling events |
0.0 | 0.4 | PID NFAT TFPATHWAY | Calcineurin-regulated NFAT-dependent transcription in lymphocytes |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
14.4 | 230.9 | REACTOME UNWINDING OF DNA | Genes involved in Unwinding of DNA |
12.5 | 224.5 | REACTOME G1 S SPECIFIC TRANSCRIPTION | Genes involved in G1/S-Specific Transcription |
11.5 | 80.6 | REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX | Genes involved in CDC6 association with the ORC:origin complex |
5.7 | 28.5 | REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX | Genes involved in Association of licensing factors with the pre-replicative complex |
5.3 | 10.6 | REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND | Genes involved in Removal of the Flap Intermediate from the C-strand |
5.0 | 69.4 | REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER | Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER |
3.8 | 15.4 | REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND | Genes involved in Processive synthesis on the lagging strand |
3.1 | 36.8 | REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS | Genes involved in Homologous recombination repair of replication-independent double-strand breaks |
2.7 | 24.6 | REACTOME G2 M DNA DAMAGE CHECKPOINT | Genes involved in G2/M DNA damage checkpoint |
2.4 | 14.5 | REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY | Genes involved in Regulation of the Fanconi anemia pathway |
1.9 | 32.0 | REACTOME G0 AND EARLY G1 | Genes involved in G0 and Early G1 |
1.4 | 38.3 | REACTOME KINESINS | Genes involved in Kinesins |
1.2 | 24.5 | REACTOME CHONDROITIN SULFATE BIOSYNTHESIS | Genes involved in Chondroitin sulfate biosynthesis |
1.1 | 52.3 | REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
1.1 | 10.6 | REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION | Genes involved in Cyclin A/B1 associated events during G2/M transition |
1.0 | 58.9 | REACTOME MEIOTIC RECOMBINATION | Genes involved in Meiotic Recombination |
1.0 | 29.6 | REACTOME G1 PHASE | Genes involved in G1 Phase |
0.7 | 12.2 | REACTOME HYALURONAN METABOLISM | Genes involved in Hyaluronan metabolism |
0.7 | 13.4 | REACTOME PURINE SALVAGE | Genes involved in Purine salvage |
0.6 | 7.9 | REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX | Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex |
0.4 | 13.8 | REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION | Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription |
0.4 | 10.0 | REACTOME REGULATION OF KIT SIGNALING | Genes involved in Regulation of KIT signaling |
0.4 | 5.7 | REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION | Genes involved in Apoptosis induced DNA fragmentation |
0.4 | 8.5 | REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
0.4 | 4.2 | REACTOME FANCONI ANEMIA PATHWAY | Genes involved in Fanconi Anemia pathway |
0.3 | 13.6 | REACTOME MRNA 3 END PROCESSING | Genes involved in mRNA 3'-end processing |
0.3 | 6.7 | REACTOME METABOLISM OF PORPHYRINS | Genes involved in Metabolism of porphyrins |
0.3 | 15.6 | REACTOME METABOLISM OF NON CODING RNA | Genes involved in Metabolism of non-coding RNA |
0.3 | 57.2 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
0.3 | 9.1 | REACTOME RNA POL I TRANSCRIPTION | Genes involved in RNA Polymerase I Transcription |
0.2 | 9.3 | REACTOME AMINE LIGAND BINDING RECEPTORS | Genes involved in Amine ligand-binding receptors |
0.2 | 23.5 | REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION | Genes involved in Factors involved in megakaryocyte development and platelet production |
0.2 | 3.8 | REACTOME METABOLISM OF POLYAMINES | Genes involved in Metabolism of polyamines |
0.2 | 2.1 | REACTOME PYRUVATE METABOLISM | Genes involved in Pyruvate metabolism |
0.2 | 10.4 | REACTOME MITOCHONDRIAL PROTEIN IMPORT | Genes involved in Mitochondrial Protein Import |
0.2 | 4.1 | REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
0.1 | 5.5 | REACTOME CHROMOSOME MAINTENANCE | Genes involved in Chromosome Maintenance |
0.1 | 4.4 | REACTOME EGFR DOWNREGULATION | Genes involved in EGFR downregulation |
0.1 | 3.1 | REACTOME DEADENYLATION OF MRNA | Genes involved in Deadenylation of mRNA |
0.1 | 2.5 | REACTOME CYTOSOLIC TRNA AMINOACYLATION | Genes involved in Cytosolic tRNA aminoacylation |
0.1 | 3.0 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
0.0 | 0.7 | REACTOME VITAMIN B5 PANTOTHENATE METABOLISM | Genes involved in Vitamin B5 (pantothenate) metabolism |
0.0 | 0.4 | REACTOME ERKS ARE INACTIVATED | Genes involved in ERKs are inactivated |
0.0 | 0.9 | REACTOME ACTIVATION OF GENES BY ATF4 | Genes involved in Activation of Genes by ATF4 |
0.0 | 0.5 | REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION | Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression |
0.0 | 1.4 | REACTOME GLYCOSPHINGOLIPID METABOLISM | Genes involved in Glycosphingolipid metabolism |
0.0 | 1.9 | REACTOME HOST INTERACTIONS OF HIV FACTORS | Genes involved in Host Interactions of HIV factors |
0.0 | 0.5 | REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
0.0 | 1.6 | REACTOME NCAM SIGNALING FOR NEURITE OUT GROWTH | Genes involved in NCAM signaling for neurite out-growth |
0.0 | 2.2 | REACTOME PEPTIDE LIGAND BINDING RECEPTORS | Genes involved in Peptide ligand-binding receptors |