avrg: GSE58827: Dynamics of the Mouse Liver
Gene Symbol | Gene ID | Gene Info |
---|---|---|
Hoxb3
|
ENSMUSG00000048763.5 | homeobox B3 |
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Hoxb3 | mm10_v2_chr11_+_96323253_96323326 | -0.46 | 4.6e-03 | Click! |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.6 | 1.7 | GO:0072204 | cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204) |
0.5 | 5.3 | GO:0071394 | cellular response to testosterone stimulus(GO:0071394) |
0.4 | 3.5 | GO:0045409 | negative regulation of interleukin-6 biosynthetic process(GO:0045409) |
0.4 | 1.6 | GO:0002439 | chronic inflammatory response to antigenic stimulus(GO:0002439) |
0.4 | 1.1 | GO:2001200 | positive regulation of dendritic cell differentiation(GO:2001200) |
0.3 | 2.3 | GO:0043415 | positive regulation of skeletal muscle tissue regeneration(GO:0043415) |
0.3 | 1.5 | GO:0072592 | oxygen metabolic process(GO:0072592) |
0.2 | 0.7 | GO:1902498 | regulation of protein autoubiquitination(GO:1902498) |
0.2 | 0.8 | GO:1901475 | pyruvate transmembrane transport(GO:1901475) |
0.2 | 0.6 | GO:2000616 | negative regulation of histone H3-K9 acetylation(GO:2000616) |
0.2 | 0.8 | GO:0030091 | protein repair(GO:0030091) |
0.2 | 0.5 | GO:0019085 | early viral transcription(GO:0019085) |
0.1 | 2.1 | GO:0015747 | urate transport(GO:0015747) |
0.1 | 1.4 | GO:0048207 | vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) |
0.1 | 0.5 | GO:0036367 | adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367) |
0.1 | 0.7 | GO:0051970 | negative regulation of transmission of nerve impulse(GO:0051970) |
0.1 | 0.5 | GO:0061030 | epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030) |
0.1 | 1.5 | GO:0030322 | stabilization of membrane potential(GO:0030322) |
0.1 | 1.3 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
0.1 | 0.5 | GO:0070162 | adiponectin secretion(GO:0070162) regulation of adiponectin secretion(GO:0070163) negative regulation of monocyte chemotactic protein-1 production(GO:0071638) |
0.1 | 0.6 | GO:0070562 | regulation of vitamin D receptor signaling pathway(GO:0070562) |
0.1 | 2.3 | GO:1902175 | regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902175) |
0.1 | 0.2 | GO:0036091 | positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091) |
0.1 | 2.3 | GO:0015985 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
0.1 | 1.1 | GO:0032525 | somite rostral/caudal axis specification(GO:0032525) |
0.1 | 1.4 | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone(GO:0006120) |
0.1 | 0.9 | GO:1901898 | negative regulation of relaxation of cardiac muscle(GO:1901898) |
0.1 | 0.5 | GO:0019532 | oxalate transport(GO:0019532) |
0.1 | 1.1 | GO:0070886 | positive regulation of calcineurin-NFAT signaling cascade(GO:0070886) |
0.1 | 0.7 | GO:0071372 | cellular response to follicle-stimulating hormone stimulus(GO:0071372) |
0.1 | 1.5 | GO:0048240 | sperm capacitation(GO:0048240) |
0.0 | 0.2 | GO:0090669 | telomerase RNA stabilization(GO:0090669) |
0.0 | 0.1 | GO:0035880 | embryonic nail plate morphogenesis(GO:0035880) positive regulation of catagen(GO:0051795) frontal suture morphogenesis(GO:0060364) |
0.0 | 0.7 | GO:0032000 | positive regulation of fatty acid beta-oxidation(GO:0032000) |
0.0 | 0.4 | GO:0009162 | deoxyribonucleoside monophosphate metabolic process(GO:0009162) |
0.0 | 1.5 | GO:0008206 | bile acid metabolic process(GO:0008206) |
0.0 | 1.5 | GO:0010758 | regulation of macrophage chemotaxis(GO:0010758) |
0.0 | 0.3 | GO:0045002 | double-strand break repair via single-strand annealing(GO:0045002) |
0.0 | 0.2 | GO:0009946 | proximal/distal axis specification(GO:0009946) |
0.0 | 0.3 | GO:0016056 | rhodopsin mediated signaling pathway(GO:0016056) |
0.0 | 0.3 | GO:1902414 | protein localization to cell junction(GO:1902414) |
0.0 | 0.2 | GO:0031848 | protection from non-homologous end joining at telomere(GO:0031848) |
0.0 | 1.6 | GO:0043029 | T cell homeostasis(GO:0043029) |
0.0 | 0.4 | GO:0032926 | negative regulation of activin receptor signaling pathway(GO:0032926) |
0.0 | 0.6 | GO:0051044 | positive regulation of membrane protein ectodomain proteolysis(GO:0051044) |
0.0 | 0.3 | GO:0046037 | GMP metabolic process(GO:0046037) |
0.0 | 0.3 | GO:0033314 | mitotic DNA replication checkpoint(GO:0033314) |
0.0 | 1.1 | GO:0042773 | ATP synthesis coupled electron transport(GO:0042773) |
0.0 | 0.4 | GO:0001778 | plasma membrane repair(GO:0001778) |
0.0 | 0.6 | GO:0007202 | activation of phospholipase C activity(GO:0007202) |
0.0 | 0.2 | GO:0070317 | negative regulation of G0 to G1 transition(GO:0070317) |
0.0 | 0.1 | GO:0090158 | endoplasmic reticulum membrane organization(GO:0090158) |
0.0 | 0.1 | GO:0040031 | snRNA modification(GO:0040031) |
0.0 | 0.1 | GO:0070934 | CRD-mediated mRNA stabilization(GO:0070934) |
0.0 | 0.2 | GO:0000712 | resolution of meiotic recombination intermediates(GO:0000712) |
0.0 | 0.0 | GO:0097212 | lysosomal membrane organization(GO:0097212) |
0.0 | 0.4 | GO:2000310 | regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310) |
0.0 | 0.1 | GO:0046947 | hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947) |
0.0 | 0.5 | GO:0006904 | vesicle docking involved in exocytosis(GO:0006904) |
0.0 | 0.1 | GO:1990118 | sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118) |
0.0 | 2.1 | GO:0035023 | regulation of Rho protein signal transduction(GO:0035023) |
0.0 | 0.1 | GO:0002913 | positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913) |
0.0 | 0.2 | GO:0022904 | respiratory electron transport chain(GO:0022904) |
0.0 | 0.7 | GO:0006805 | xenobiotic metabolic process(GO:0006805) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 1.3 | GO:0005608 | laminin-3 complex(GO:0005608) |
0.1 | 2.1 | GO:0000276 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) |
0.1 | 0.6 | GO:0005726 | perichromatin fibrils(GO:0005726) |
0.1 | 1.2 | GO:0035686 | sperm fibrous sheath(GO:0035686) |
0.0 | 0.9 | GO:0000930 | gamma-tubulin complex(GO:0000930) |
0.0 | 1.1 | GO:0031307 | integral component of mitochondrial outer membrane(GO:0031307) |
0.0 | 0.3 | GO:0045261 | mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261) |
0.0 | 0.3 | GO:0036128 | CatSper complex(GO:0036128) |
0.0 | 2.5 | GO:0070469 | respiratory chain(GO:0070469) |
0.0 | 0.2 | GO:0030015 | CCR4-NOT core complex(GO:0030015) |
0.0 | 0.1 | GO:0014701 | junctional sarcoplasmic reticulum membrane(GO:0014701) |
0.0 | 0.2 | GO:0070419 | nonhomologous end joining complex(GO:0070419) |
0.0 | 0.1 | GO:0070937 | CRD-mediated mRNA stability complex(GO:0070937) |
0.0 | 0.2 | GO:0000812 | Swr1 complex(GO:0000812) |
0.0 | 0.4 | GO:0090545 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
0.0 | 2.7 | GO:0031225 | anchored component of membrane(GO:0031225) |
0.0 | 0.6 | GO:0042645 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
0.0 | 0.4 | GO:0031305 | integral component of mitochondrial inner membrane(GO:0031305) |
0.0 | 0.1 | GO:0097550 | transcriptional preinitiation complex(GO:0097550) |
0.0 | 0.2 | GO:0005665 | DNA-directed RNA polymerase II, core complex(GO:0005665) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.8 | 5.3 | GO:0005009 | insulin-activated receptor activity(GO:0005009) pheromone activity(GO:0005186) |
0.4 | 1.3 | GO:0008113 | peptide-methionine (S)-S-oxide reductase activity(GO:0008113) |
0.3 | 1.5 | GO:0008410 | acetyl-CoA C-acetyltransferase activity(GO:0003985) CoA-transferase activity(GO:0008410) palmitoyl-CoA oxidase activity(GO:0016401) C-acetyltransferase activity(GO:0016453) |
0.2 | 1.6 | GO:0016802 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
0.2 | 2.3 | GO:0031545 | peptidyl-proline 4-dioxygenase activity(GO:0031545) |
0.2 | 0.8 | GO:0050833 | pyruvate transmembrane transporter activity(GO:0050833) |
0.2 | 0.8 | GO:0033743 | peptide-methionine (R)-S-oxide reductase activity(GO:0033743) |
0.2 | 0.6 | GO:0036132 | 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522) |
0.2 | 0.6 | GO:0016501 | prostacyclin receptor activity(GO:0016501) |
0.2 | 1.5 | GO:0004499 | N,N-dimethylaniline monooxygenase activity(GO:0004499) |
0.2 | 1.1 | GO:0038132 | neuregulin binding(GO:0038132) |
0.1 | 0.7 | GO:0016416 | carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416) |
0.1 | 2.1 | GO:1901702 | urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702) |
0.1 | 2.1 | GO:0046933 | proton-transporting ATP synthase activity, rotational mechanism(GO:0046933) |
0.1 | 3.5 | GO:0030247 | pattern binding(GO:0001871) polysaccharide binding(GO:0030247) |
0.1 | 1.7 | GO:0016500 | protein-hormone receptor activity(GO:0016500) |
0.1 | 1.5 | GO:0022841 | potassium ion leak channel activity(GO:0022841) |
0.1 | 2.5 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
0.1 | 0.3 | GO:0008534 | oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534) |
0.1 | 0.5 | GO:0017040 | ceramidase activity(GO:0017040) |
0.1 | 0.7 | GO:0005004 | GPI-linked ephrin receptor activity(GO:0005004) |
0.1 | 0.6 | GO:0061665 | SUMO ligase activity(GO:0061665) |
0.1 | 0.6 | GO:0034056 | estrogen response element binding(GO:0034056) |
0.1 | 1.6 | GO:0045125 | bioactive lipid receptor activity(GO:0045125) |
0.1 | 0.3 | GO:0030292 | protein tyrosine kinase inhibitor activity(GO:0030292) |
0.1 | 0.4 | GO:0004687 | myosin light chain kinase activity(GO:0004687) |
0.1 | 0.4 | GO:0070699 | type II activin receptor binding(GO:0070699) |
0.0 | 1.9 | GO:0015020 | glucuronosyltransferase activity(GO:0015020) |
0.0 | 0.6 | GO:0019855 | calcium channel inhibitor activity(GO:0019855) |
0.0 | 0.5 | GO:0008429 | phosphatidylethanolamine binding(GO:0008429) |
0.0 | 1.1 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
0.0 | 1.6 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
0.0 | 0.2 | GO:0051880 | G-quadruplex DNA binding(GO:0051880) |
0.0 | 0.3 | GO:0008020 | G-protein coupled photoreceptor activity(GO:0008020) |
0.0 | 1.1 | GO:0031435 | mitogen-activated protein kinase kinase kinase binding(GO:0031435) |
0.0 | 0.5 | GO:0019531 | oxalate transmembrane transporter activity(GO:0019531) |
0.0 | 0.7 | GO:0004033 | aldo-keto reductase (NADP) activity(GO:0004033) |
0.0 | 0.7 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
0.0 | 0.2 | GO:0097322 | 7SK snRNA binding(GO:0097322) |
0.0 | 1.1 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
0.0 | 0.2 | GO:0035312 | 5'-3' exodeoxyribonuclease activity(GO:0035312) |
0.0 | 0.6 | GO:0008327 | methyl-CpG binding(GO:0008327) |
0.0 | 0.1 | GO:0046912 | transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912) |
0.0 | 0.3 | GO:0008641 | small protein activating enzyme activity(GO:0008641) |
0.0 | 2.5 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
0.0 | 0.6 | GO:0043274 | phospholipase binding(GO:0043274) |
0.0 | 0.2 | GO:0015279 | store-operated calcium channel activity(GO:0015279) |
0.0 | 0.1 | GO:0008475 | procollagen-lysine 5-dioxygenase activity(GO:0008475) |
0.0 | 0.1 | GO:0015386 | potassium:proton antiporter activity(GO:0015386) |
0.0 | 0.0 | GO:0031686 | A1 adenosine receptor binding(GO:0031686) |
0.0 | 0.3 | GO:0047555 | 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 1.3 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
0.1 | 3.5 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
0.1 | 1.1 | PID ERBB NETWORK PATHWAY | ErbB receptor signaling network |
0.0 | 1.1 | PID INTEGRIN2 PATHWAY | Beta2 integrin cell surface interactions |
0.0 | 2.7 | PID RHOA REG PATHWAY | Regulation of RhoA activity |
0.0 | 0.7 | PID EPHA FWDPATHWAY | EPHA forward signaling |
0.0 | 0.4 | ST G ALPHA S PATHWAY | G alpha s Pathway |
0.0 | 0.6 | PID RXR VDR PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
0.0 | 0.7 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 1.5 | REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS | Genes involved in Tandem pore domain potassium channels |
0.1 | 2.1 | REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING | Genes involved in Formation of ATP by chemiosmotic coupling |
0.1 | 1.6 | REACTOME SULFUR AMINO ACID METABOLISM | Genes involved in Sulfur amino acid metabolism |
0.1 | 1.1 | REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING | Genes involved in Downregulation of ERBB2:ERBB3 signaling |
0.0 | 0.3 | REACTOME OPSINS | Genes involved in Opsins |
0.0 | 1.5 | REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
0.0 | 0.4 | REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
0.0 | 1.2 | REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS | Genes involved in Phase 1 - Functionalization of compounds |
0.0 | 0.7 | REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE | Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle |
0.0 | 0.2 | REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS | Genes involved in Elevation of cytosolic Ca2+ levels |
0.0 | 0.3 | REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY | Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway |
0.0 | 1.1 | REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
0.0 | 0.9 | REACTOME DARPP 32 EVENTS | Genes involved in DARPP-32 events |
0.0 | 0.4 | REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR | Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor |
0.0 | 0.6 | REACTOME SIGNALING BY FGFR1 FUSION MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |
0.0 | 0.5 | REACTOME GLYCOSPHINGOLIPID METABOLISM | Genes involved in Glycosphingolipid metabolism |
0.0 | 1.3 | REACTOME CELL JUNCTION ORGANIZATION | Genes involved in Cell junction organization |