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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Sox11

Z-value: 0.62

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Transcription factors associated with Sox11

Gene Symbol Gene ID Gene Info
ENSMUSG00000063632.5 SRY (sex determining region Y)-box 11

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Sox11mm10_v2_chr12_-_27342696_27342726-0.572.5e-04Click!

Activity profile of Sox11 motif

Sorted Z-values of Sox11 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Sox11

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 4.2 GO:0071394 cellular response to testosterone stimulus(GO:0071394)
0.3 0.8 GO:0099526 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
0.1 0.5 GO:0006624 vacuolar protein processing(GO:0006624)
0.1 0.3 GO:1900135 positive regulation of renin secretion into blood stream(GO:1900135)
0.1 0.5 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.1 0.5 GO:1902965 regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
0.1 0.3 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.1 0.3 GO:0009441 glycolate metabolic process(GO:0009441)
0.1 0.2 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.1 0.4 GO:1990592 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.1 0.2 GO:0030043 actin filament fragmentation(GO:0030043)
0.1 1.5 GO:0015701 bicarbonate transport(GO:0015701)
0.1 0.7 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.1 GO:1900210 positive regulation of mitochondrial DNA replication(GO:0090297) regulation of cardiolipin metabolic process(GO:1900208) positive regulation of cardiolipin metabolic process(GO:1900210) stress-induced mitochondrial fusion(GO:1990046)
0.0 0.3 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.1 GO:0046381 CMP-N-acetylneuraminate metabolic process(GO:0046381)
0.0 0.5 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.4 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.6 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.7 GO:0010842 retina layer formation(GO:0010842)
0.0 0.2 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 0.4 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.3 GO:0006047 UDP-N-acetylglucosamine metabolic process(GO:0006047) N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.2 GO:0033572 transferrin transport(GO:0033572)
0.0 0.2 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 0.8 GO:0050907 detection of chemical stimulus involved in sensory perception(GO:0050907)
0.0 1.1 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.2 GO:0035376 sterol import(GO:0035376) cholesterol import(GO:0070508)
0.0 0.2 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0 0.0 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.0 0.2 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0044317 rod spherule(GO:0044317)
0.1 0.5 GO:0097361 CIA complex(GO:0097361)
0.1 1.3 GO:0044292 dendrite terminus(GO:0044292)
0.0 0.3 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.0 0.5 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.5 GO:0051286 cell tip(GO:0051286)
0.0 0.5 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 0.4 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.2 GO:0005009 insulin-activated receptor activity(GO:0005009) pheromone activity(GO:0005186)
0.2 1.0 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.1 0.4 GO:0071568 UFM1 transferase activity(GO:0071568)
0.1 0.6 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 0.3 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.1 1.5 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 0.7 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 0.3 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1 0.8 GO:0005522 profilin binding(GO:0005522)
0.1 1.3 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 0.3 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.3 GO:0008761 UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761)
0.0 0.3 GO:0005223 intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223)
0.0 0.1 GO:0030338 CMP-N-acetylneuraminate monooxygenase activity(GO:0030338)
0.0 0.5 GO:0004579 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.1 GO:0042015 interleukin-20 binding(GO:0042015)
0.0 0.2 GO:0032052 bile acid binding(GO:0032052)
0.0 0.2 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.0 0.1 GO:1901612 cardiolipin binding(GO:1901612)
0.0 1.1 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.4 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.3 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.4 GO:0042165 neurotransmitter binding(GO:0042165)
0.0 0.2 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.7 GO:0005549 odorant binding(GO:0005549)
0.0 0.3 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 2.0 GO:0015293 symporter activity(GO:0015293)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.5 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.2 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.7 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 1.5 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.5 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1