avrg: GSE58827: Dynamics of the Mouse Liver
Gene Symbol | Gene ID | Gene Info |
---|---|---|
Lhx8
|
ENSMUSG00000096225.2 | LIM homeobox protein 8 |
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Lhx8 | mm10_v2_chr3_-_154330543_154330576 | -0.21 | 2.1e-01 | Click! |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.7 | 5.0 | GO:0043387 | mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) |
0.7 | 2.2 | GO:0061402 | positive regulation of transcription from RNA polymerase II promoter in response to acidic pH(GO:0061402) |
0.6 | 2.4 | GO:0045329 | carnitine biosynthetic process(GO:0045329) |
0.4 | 1.9 | GO:0015788 | UDP-N-acetylglucosamine transport(GO:0015788) |
0.3 | 1.2 | GO:0090126 | protein complex assembly involved in synapse maturation(GO:0090126) |
0.2 | 0.9 | GO:2000439 | positive regulation of monocyte extravasation(GO:2000439) |
0.2 | 2.1 | GO:0019227 | neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870) |
0.2 | 2.2 | GO:0070131 | positive regulation of mitochondrial translation(GO:0070131) |
0.2 | 0.7 | GO:0060128 | corticotropin hormone secreting cell differentiation(GO:0060128) |
0.1 | 2.1 | GO:0030497 | fatty acid elongation(GO:0030497) |
0.1 | 0.4 | GO:0032058 | positive regulation of translational initiation in response to stress(GO:0032058) |
0.1 | 0.6 | GO:0001920 | negative regulation of receptor recycling(GO:0001920) |
0.1 | 3.8 | GO:0019373 | epoxygenase P450 pathway(GO:0019373) |
0.1 | 0.3 | GO:0090526 | regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526) |
0.1 | 0.3 | GO:0042539 | hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477) |
0.1 | 4.6 | GO:0006958 | complement activation, classical pathway(GO:0006958) |
0.1 | 1.4 | GO:0060501 | positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501) |
0.1 | 0.9 | GO:0050955 | thermoception(GO:0050955) |
0.1 | 0.7 | GO:0008611 | ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503) |
0.1 | 0.2 | GO:2000583 | regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584) |
0.1 | 0.7 | GO:0010739 | positive regulation of protein kinase A signaling(GO:0010739) |
0.1 | 1.0 | GO:1990440 | positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440) |
0.1 | 0.4 | GO:0090070 | positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234) |
0.1 | 0.2 | GO:0010579 | regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579) |
0.1 | 0.2 | GO:0043152 | induction of bacterial agglutination(GO:0043152) |
0.1 | 0.2 | GO:0006296 | base-excision repair, AP site formation(GO:0006285) nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296) |
0.1 | 0.2 | GO:0099566 | regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566) |
0.0 | 3.0 | GO:0003298 | physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049) |
0.0 | 3.6 | GO:0006749 | glutathione metabolic process(GO:0006749) |
0.0 | 1.0 | GO:0008090 | retrograde axonal transport(GO:0008090) |
0.0 | 1.4 | GO:0046688 | response to copper ion(GO:0046688) |
0.0 | 1.3 | GO:0010758 | regulation of macrophage chemotaxis(GO:0010758) |
0.0 | 0.3 | GO:0003356 | regulation of cilium beat frequency(GO:0003356) |
0.0 | 0.2 | GO:0046552 | eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552) |
0.0 | 0.7 | GO:0034453 | microtubule anchoring(GO:0034453) |
0.0 | 0.5 | GO:0001580 | detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580) |
0.0 | 0.9 | GO:0010107 | potassium ion import(GO:0010107) |
0.0 | 1.2 | GO:0051180 | vitamin transport(GO:0051180) |
0.0 | 0.1 | GO:2000595 | optic nerve formation(GO:0021634) regulation of metanephros size(GO:0035566) optic chiasma development(GO:0061360) regulation of optic nerve formation(GO:2000595) positive regulation of optic nerve formation(GO:2000597) |
0.0 | 0.5 | GO:0006491 | N-glycan processing(GO:0006491) |
0.0 | 0.1 | GO:0070459 | prolactin secretion(GO:0070459) |
0.0 | 0.3 | GO:0016998 | cell wall macromolecule catabolic process(GO:0016998) |
0.0 | 0.6 | GO:0050907 | detection of chemical stimulus involved in sensory perception(GO:0050907) |
0.0 | 0.4 | GO:0021702 | cerebellar Purkinje cell differentiation(GO:0021702) |
0.0 | 1.1 | GO:0030835 | negative regulation of actin filament depolymerization(GO:0030835) |
0.0 | 0.7 | GO:0006829 | zinc II ion transport(GO:0006829) |
0.0 | 0.1 | GO:0090234 | regulation of kinetochore assembly(GO:0090234) |
0.0 | 0.2 | GO:2001269 | positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269) |
0.0 | 0.4 | GO:0071392 | cellular response to estradiol stimulus(GO:0071392) |
0.0 | 0.1 | GO:0032790 | ribosome disassembly(GO:0032790) |
0.0 | 0.1 | GO:0061143 | alveolar primary septum development(GO:0061143) |
0.0 | 0.5 | GO:0006891 | intra-Golgi vesicle-mediated transport(GO:0006891) |
0.0 | 0.3 | GO:0030238 | male sex determination(GO:0030238) |
0.0 | 0.3 | GO:0050901 | leukocyte tethering or rolling(GO:0050901) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.2 | 3.7 | GO:0097057 | TRAF2-GSTP1 complex(GO:0097057) |
0.4 | 1.3 | GO:0034657 | GID complex(GO:0034657) |
0.2 | 1.0 | GO:0031673 | H zone(GO:0031673) |
0.1 | 0.4 | GO:1903439 | calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440) |
0.1 | 1.2 | GO:0036057 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
0.1 | 0.8 | GO:0005687 | U4 snRNP(GO:0005687) |
0.0 | 0.7 | GO:0000276 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) |
0.0 | 0.4 | GO:0030688 | preribosome, small subunit precursor(GO:0030688) |
0.0 | 2.1 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
0.0 | 0.5 | GO:0017119 | Golgi transport complex(GO:0017119) |
0.0 | 2.8 | GO:0044438 | microbody part(GO:0044438) peroxisomal part(GO:0044439) |
0.0 | 0.2 | GO:0005577 | fibrinogen complex(GO:0005577) |
0.0 | 1.4 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
0.0 | 1.9 | GO:0042734 | presynaptic membrane(GO:0042734) |
0.0 | 0.6 | GO:0042101 | T cell receptor complex(GO:0042101) |
0.0 | 0.4 | GO:0016514 | SWI/SNF complex(GO:0016514) |
0.0 | 1.1 | GO:0032154 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
0.0 | 0.2 | GO:0031597 | cytosolic proteasome complex(GO:0031597) |
0.0 | 0.3 | GO:0016010 | dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665) |
0.0 | 0.8 | GO:0005844 | polysome(GO:0005844) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
3.0 | 8.9 | GO:0016838 | carbon-oxygen lyase activity, acting on phosphates(GO:0016838) |
0.7 | 2.1 | GO:0019166 | trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166) |
0.4 | 1.2 | GO:0008431 | vitamin E binding(GO:0008431) |
0.3 | 0.8 | GO:1902121 | NADP+ binding(GO:0070401) lithocholic acid binding(GO:1902121) |
0.2 | 0.7 | GO:0004948 | calcitonin receptor activity(GO:0004948) |
0.2 | 2.3 | GO:0001594 | trace-amine receptor activity(GO:0001594) |
0.2 | 8.7 | GO:0004364 | glutathione transferase activity(GO:0004364) |
0.2 | 6.2 | GO:0015020 | glucuronosyltransferase activity(GO:0015020) |
0.1 | 1.4 | GO:0004322 | ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724) |
0.1 | 0.7 | GO:0030292 | protein tyrosine kinase inhibitor activity(GO:0030292) |
0.1 | 0.5 | GO:0031849 | olfactory receptor binding(GO:0031849) |
0.1 | 3.8 | GO:0070330 | aromatase activity(GO:0070330) |
0.1 | 2.1 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
0.1 | 0.3 | GO:0016262 | protein N-acetylglucosaminyltransferase activity(GO:0016262) |
0.1 | 0.3 | GO:0035827 | rubidium ion transmembrane transporter activity(GO:0035827) |
0.1 | 2.2 | GO:0004550 | nucleoside diphosphate kinase activity(GO:0004550) |
0.1 | 1.2 | GO:0097109 | neuroligin family protein binding(GO:0097109) |
0.1 | 1.9 | GO:0005351 | sugar:proton symporter activity(GO:0005351) |
0.1 | 0.7 | GO:0000268 | peroxisome targeting sequence binding(GO:0000268) |
0.1 | 0.5 | GO:0004571 | mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) |
0.1 | 1.0 | GO:0035497 | cAMP response element binding(GO:0035497) |
0.0 | 0.9 | GO:0005161 | platelet-derived growth factor receptor binding(GO:0005161) |
0.0 | 0.7 | GO:0016805 | dipeptidase activity(GO:0016805) |
0.0 | 0.1 | GO:0033142 | progesterone receptor binding(GO:0033142) |
0.0 | 0.4 | GO:0030274 | LIM domain binding(GO:0030274) |
0.0 | 2.4 | GO:0016706 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706) |
0.0 | 0.3 | GO:0033691 | sialic acid binding(GO:0033691) |
0.0 | 0.2 | GO:0000702 | oxidized base lesion DNA N-glycosylase activity(GO:0000702) |
0.0 | 0.9 | GO:0005242 | inward rectifier potassium channel activity(GO:0005242) |
0.0 | 0.4 | GO:0050692 | DBD domain binding(GO:0050692) |
0.0 | 1.1 | GO:0003785 | actin monomer binding(GO:0003785) |
0.0 | 1.7 | GO:0030374 | ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374) |
0.0 | 0.2 | GO:0099529 | neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583) |
0.0 | 0.3 | GO:0003796 | lysozyme activity(GO:0003796) |
0.0 | 1.1 | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547) |
0.0 | 0.3 | GO:0008301 | DNA binding, bending(GO:0008301) |
0.0 | 2.3 | GO:0052689 | carboxylic ester hydrolase activity(GO:0052689) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 2.2 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
0.0 | 1.1 | PID ARF6 PATHWAY | Arf6 signaling events |
0.0 | 1.0 | PID P38 ALPHA BETA DOWNSTREAM PATHWAY | Signaling mediated by p38-alpha and p38-beta |
0.0 | 1.7 | PID ECADHERIN STABILIZATION PATHWAY | Stabilization and expansion of the E-cadherin adherens junction |
0.0 | 1.1 | PID UPA UPAR PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
0.0 | 0.7 | PID SYNDECAN 4 PATHWAY | Syndecan-4-mediated signaling events |
0.0 | 1.4 | PID HIF1 TFPATHWAY | HIF-1-alpha transcription factor network |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 2.2 | REACTOME ABACAVIR TRANSPORT AND METABOLISM | Genes involved in Abacavir transport and metabolism |
0.1 | 5.0 | REACTOME GLUTATHIONE CONJUGATION | Genes involved in Glutathione conjugation |
0.1 | 1.0 | REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA | Genes involved in Activation of Chaperone Genes by ATF6-alpha |
0.0 | 1.9 | REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES | Genes involved in Transport of vitamins, nucleosides, and related molecules |
0.0 | 0.7 | REACTOME SIGNALING BY FGFR3 MUTANTS | Genes involved in Signaling by FGFR3 mutants |
0.0 | 2.1 | REACTOME NCAM1 INTERACTIONS | Genes involved in NCAM1 interactions |
0.0 | 1.4 | REACTOME METAL ION SLC TRANSPORTERS | Genes involved in Metal ion SLC transporters |
0.0 | 0.6 | REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING | Genes involved in Formation of ATP by chemiosmotic coupling |
0.0 | 0.2 | REACTOME CREATION OF C4 AND C2 ACTIVATORS | Genes involved in Creation of C4 and C2 activators |
0.0 | 0.6 | REACTOME DOWNSTREAM TCR SIGNALING | Genes involved in Downstream TCR signaling |
0.0 | 0.7 | REACTOME SIGNALING BY FGFR1 FUSION MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |
0.0 | 0.9 | REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS | Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits |
0.0 | 0.2 | REACTOME COMMON PATHWAY | Genes involved in Common Pathway |
0.0 | 0.5 | REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION | Genes involved in Transport to the Golgi and subsequent modification |