avrg: GSE58827: Dynamics of the Mouse Liver
Gene Symbol | Gene ID | Gene Info |
---|---|---|
Nkx2-1
|
ENSMUSG00000001496.9 | NK2 homeobox 1 |
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Nkx2-1 | mm10_v2_chr12_-_56536895_56536937 | 0.24 | 1.6e-01 | Click! |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.7 | 13.3 | GO:1901750 | leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750) |
0.9 | 6.9 | GO:0006776 | vitamin A metabolic process(GO:0006776) |
0.8 | 4.7 | GO:0031536 | positive regulation of exit from mitosis(GO:0031536) |
0.6 | 1.7 | GO:0046005 | positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005) |
0.5 | 1.4 | GO:1904956 | regulation of midbrain dopaminergic neuron differentiation(GO:1904956) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041) |
0.4 | 1.5 | GO:0033030 | negative regulation of neutrophil apoptotic process(GO:0033030) |
0.4 | 1.8 | GO:0097167 | circadian regulation of translation(GO:0097167) |
0.3 | 3.5 | GO:0015705 | iodide transport(GO:0015705) |
0.3 | 1.7 | GO:1903059 | regulation of protein lipidation(GO:1903059) |
0.3 | 1.1 | GO:0001992 | regulation of systemic arterial blood pressure by vasopressin(GO:0001992) |
0.3 | 3.4 | GO:2000381 | negative regulation of mesoderm development(GO:2000381) |
0.3 | 1.0 | GO:0014846 | esophagus smooth muscle contraction(GO:0014846) |
0.2 | 1.6 | GO:0071313 | cellular response to caffeine(GO:0071313) |
0.2 | 0.7 | GO:0014873 | response to muscle activity involved in regulation of muscle adaptation(GO:0014873) |
0.2 | 2.3 | GO:0035520 | monoubiquitinated protein deubiquitination(GO:0035520) |
0.2 | 2.4 | GO:0035898 | parathyroid hormone secretion(GO:0035898) calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035) |
0.2 | 1.0 | GO:1903215 | negative regulation of protein targeting to mitochondrion(GO:1903215) |
0.2 | 0.8 | GO:0010760 | negative regulation of macrophage chemotaxis(GO:0010760) |
0.2 | 0.5 | GO:0051866 | general adaptation syndrome(GO:0051866) |
0.2 | 0.7 | GO:1904306 | response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109) positive regulation of gastro-intestinal system smooth muscle contraction(GO:1904306) |
0.2 | 1.1 | GO:2000767 | positive regulation of cytoplasmic translation(GO:2000767) |
0.1 | 1.2 | GO:0030579 | ubiquitin-dependent SMAD protein catabolic process(GO:0030579) |
0.1 | 1.8 | GO:2000042 | negative regulation of double-strand break repair via homologous recombination(GO:2000042) |
0.1 | 2.5 | GO:2000001 | regulation of DNA damage checkpoint(GO:2000001) |
0.1 | 0.3 | GO:0019046 | release from viral latency(GO:0019046) |
0.1 | 1.4 | GO:2001135 | regulation of endocytic recycling(GO:2001135) |
0.1 | 7.8 | GO:0030819 | positive regulation of cAMP biosynthetic process(GO:0030819) |
0.1 | 0.9 | GO:0038031 | non-canonical Wnt signaling pathway via JNK cascade(GO:0038031) |
0.1 | 1.2 | GO:0034472 | snRNA 3'-end processing(GO:0034472) |
0.1 | 1.5 | GO:0035721 | intraciliary retrograde transport(GO:0035721) |
0.1 | 0.9 | GO:0070072 | vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072) |
0.1 | 1.0 | GO:0007501 | mesodermal cell fate specification(GO:0007501) |
0.1 | 0.2 | GO:0072034 | renal vesicle induction(GO:0072034) |
0.1 | 1.4 | GO:0031280 | negative regulation of adenylate cyclase activity(GO:0007194) negative regulation of cyclase activity(GO:0031280) |
0.1 | 0.6 | GO:0090527 | actin filament reorganization(GO:0090527) |
0.1 | 0.7 | GO:0035878 | nail development(GO:0035878) |
0.1 | 1.4 | GO:0051573 | lateral ventricle development(GO:0021670) negative regulation of histone H3-K9 methylation(GO:0051573) |
0.1 | 0.3 | GO:0042699 | follicle-stimulating hormone signaling pathway(GO:0042699) |
0.1 | 3.7 | GO:0007585 | respiratory gaseous exchange(GO:0007585) |
0.0 | 1.0 | GO:0032060 | bleb assembly(GO:0032060) |
0.0 | 0.3 | GO:1990481 | mRNA pseudouridine synthesis(GO:1990481) |
0.0 | 0.9 | GO:0035428 | hexose transmembrane transport(GO:0035428) |
0.0 | 0.5 | GO:0061635 | regulation of protein complex stability(GO:0061635) |
0.0 | 0.7 | GO:0006999 | nuclear pore organization(GO:0006999) |
0.0 | 0.5 | GO:2001256 | regulation of store-operated calcium entry(GO:2001256) |
0.0 | 0.8 | GO:0034389 | lipid particle organization(GO:0034389) |
0.0 | 0.2 | GO:0070601 | centromeric sister chromatid cohesion(GO:0070601) |
0.0 | 0.3 | GO:0071397 | cellular response to cholesterol(GO:0071397) |
0.0 | 2.3 | GO:2000179 | positive regulation of neural precursor cell proliferation(GO:2000179) |
0.0 | 1.2 | GO:0048013 | ephrin receptor signaling pathway(GO:0048013) |
0.0 | 0.7 | GO:0007130 | synaptonemal complex assembly(GO:0007130) |
0.0 | 0.6 | GO:0001553 | luteinization(GO:0001553) |
0.0 | 1.5 | GO:0045471 | response to ethanol(GO:0045471) |
0.0 | 2.6 | GO:0007586 | digestion(GO:0007586) |
0.0 | 0.1 | GO:0014707 | branchiomeric skeletal muscle development(GO:0014707) |
0.0 | 1.3 | GO:0016126 | sterol biosynthetic process(GO:0016126) |
0.0 | 0.1 | GO:0010571 | positive regulation of nuclear cell cycle DNA replication(GO:0010571) |
0.0 | 0.3 | GO:0031290 | retinal ganglion cell axon guidance(GO:0031290) |
0.0 | 0.2 | GO:1901844 | regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844) negative regulation of relaxation of cardiac muscle(GO:1901898) |
0.0 | 1.0 | GO:0006998 | nuclear envelope organization(GO:0006998) |
0.0 | 2.1 | GO:0000910 | cytokinesis(GO:0000910) |
0.0 | 0.3 | GO:0071260 | cellular response to mechanical stimulus(GO:0071260) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.9 | 4.7 | GO:0031021 | interphase microtubule organizing center(GO:0031021) |
0.4 | 5.0 | GO:0097208 | alveolar lamellar body(GO:0097208) |
0.4 | 1.6 | GO:0014802 | terminal cisterna(GO:0014802) |
0.3 | 1.7 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
0.3 | 2.1 | GO:0005826 | actomyosin contractile ring(GO:0005826) |
0.2 | 3.5 | GO:0031616 | spindle pole centrosome(GO:0031616) |
0.2 | 1.5 | GO:0030991 | intraciliary transport particle A(GO:0030991) |
0.1 | 2.1 | GO:0005652 | nuclear lamina(GO:0005652) |
0.1 | 1.5 | GO:0042629 | mast cell granule(GO:0042629) |
0.1 | 1.1 | GO:0042788 | polysomal ribosome(GO:0042788) |
0.1 | 1.2 | GO:0032039 | integrator complex(GO:0032039) |
0.1 | 0.7 | GO:0000801 | central element(GO:0000801) |
0.1 | 0.9 | GO:0043205 | microfibril(GO:0001527) fibril(GO:0043205) |
0.0 | 0.6 | GO:0097539 | ciliary transition fiber(GO:0097539) |
0.0 | 1.8 | GO:1990391 | DNA repair complex(GO:1990391) |
0.0 | 0.7 | GO:0030056 | hemidesmosome(GO:0030056) |
0.0 | 5.3 | GO:0001650 | fibrillar center(GO:0001650) |
0.0 | 0.2 | GO:0031415 | NatA complex(GO:0031415) |
0.0 | 0.3 | GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671) |
0.0 | 1.4 | GO:0005581 | collagen trimer(GO:0005581) |
0.0 | 22.1 | GO:0005615 | extracellular space(GO:0005615) |
0.0 | 0.5 | GO:0043034 | costamere(GO:0043034) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.2 | 7.4 | GO:0004977 | melanocortin receptor activity(GO:0004977) |
1.1 | 13.3 | GO:0036374 | glutathione hydrolase activity(GO:0036374) |
0.5 | 1.6 | GO:0005219 | ryanodine-sensitive calcium-release channel activity(GO:0005219) |
0.5 | 1.5 | GO:0019959 | interleukin-8 binding(GO:0019959) |
0.5 | 6.9 | GO:0019841 | retinal binding(GO:0016918) retinol binding(GO:0019841) |
0.4 | 2.7 | GO:0061649 | ubiquitinated histone binding(GO:0061649) |
0.2 | 1.0 | GO:0008449 | N-acetylglucosamine-6-sulfatase activity(GO:0008449) |
0.2 | 1.3 | GO:0070087 | chromo shadow domain binding(GO:0070087) |
0.1 | 1.2 | GO:0048495 | Roundabout binding(GO:0048495) |
0.1 | 1.1 | GO:0005000 | vasopressin receptor activity(GO:0005000) |
0.1 | 2.8 | GO:0003746 | translation elongation factor activity(GO:0003746) |
0.1 | 5.1 | GO:0008536 | Ran GTPase binding(GO:0008536) |
0.1 | 2.3 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
0.1 | 0.7 | GO:0038132 | neuregulin binding(GO:0038132) |
0.1 | 0.7 | GO:0004716 | receptor signaling protein tyrosine kinase activity(GO:0004716) |
0.1 | 0.3 | GO:0031826 | type 2A serotonin receptor binding(GO:0031826) |
0.1 | 0.6 | GO:0004726 | non-membrane spanning protein tyrosine phosphatase activity(GO:0004726) |
0.1 | 2.0 | GO:0023026 | MHC class II protein complex binding(GO:0023026) |
0.1 | 0.6 | GO:0008889 | glycerophosphodiester phosphodiesterase activity(GO:0008889) |
0.0 | 1.7 | GO:0071855 | neuropeptide receptor binding(GO:0071855) |
0.0 | 0.5 | GO:0031802 | type 5 metabotropic glutamate receptor binding(GO:0031802) |
0.0 | 2.6 | GO:0070888 | E-box binding(GO:0070888) |
0.0 | 0.3 | GO:0043995 | histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972) |
0.0 | 0.9 | GO:0005351 | sugar:proton symporter activity(GO:0005351) |
0.0 | 3.5 | GO:0005179 | hormone activity(GO:0005179) |
0.0 | 0.3 | GO:0022833 | mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833) |
0.0 | 0.7 | GO:0005487 | nucleocytoplasmic transporter activity(GO:0005487) |
0.0 | 0.4 | GO:0016500 | protein-hormone receptor activity(GO:0016500) |
0.0 | 0.2 | GO:0010485 | H4 histone acetyltransferase activity(GO:0010485) |
0.0 | 1.2 | GO:0046875 | ephrin receptor binding(GO:0046875) |
0.0 | 0.1 | GO:0004365 | glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891) |
0.0 | 2.4 | GO:0005262 | calcium channel activity(GO:0005262) |
0.0 | 4.6 | GO:0001664 | G-protein coupled receptor binding(GO:0001664) |
0.0 | 0.3 | GO:0009982 | pseudouridine synthase activity(GO:0009982) |
0.0 | 0.5 | GO:0035259 | glucocorticoid receptor binding(GO:0035259) |
0.0 | 3.2 | GO:0004721 | phosphoprotein phosphatase activity(GO:0004721) |
0.0 | 1.1 | GO:0004197 | cysteine-type endopeptidase activity(GO:0004197) |
0.0 | 0.1 | GO:0003810 | protein-glutamine gamma-glutamyltransferase activity(GO:0003810) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 8.1 | PID AURORA A PATHWAY | Aurora A signaling |
0.1 | 1.8 | PID CIRCADIAN PATHWAY | Circadian rhythm pathway |
0.1 | 0.6 | PID EPHA2 FWD PATHWAY | EPHA2 forward signaling |
0.1 | 6.1 | PID RB 1PATHWAY | Regulation of retinoblastoma protein |
0.1 | 0.7 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
0.0 | 1.5 | ST MYOCYTE AD PATHWAY | Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway. |
0.0 | 1.5 | ST GRANULE CELL SURVIVAL PATHWAY | Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway. |
0.0 | 1.4 | ST WNT BETA CATENIN PATHWAY | Wnt/beta-catenin Pathway |
0.0 | 2.4 | PID PTP1B PATHWAY | Signaling events mediated by PTP1B |
0.0 | 0.9 | PID WNT SIGNALING PATHWAY | Wnt signaling network |
0.0 | 1.3 | PID FANCONI PATHWAY | Fanconi anemia pathway |
0.0 | 4.8 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
0.0 | 1.5 | PID ARF6 TRAFFICKING PATHWAY | Arf6 trafficking events |
0.0 | 1.0 | PID A6B1 A6B4 INTEGRIN PATHWAY | a6b1 and a6b4 Integrin signaling |
0.0 | 1.1 | PID ERBB1 INTERNALIZATION PATHWAY | Internalization of ErbB1 |
0.0 | 2.1 | PID CMYB PATHWAY | C-MYB transcription factor network |
0.0 | 1.2 | PID RAC1 REG PATHWAY | Regulation of RAC1 activity |
0.0 | 0.3 | PID NFKAPPAB ATYPICAL PATHWAY | Atypical NF-kappaB pathway |
0.0 | 1.1 | PID MTOR 4PATHWAY | mTOR signaling pathway |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 13.3 | REACTOME GLUTATHIONE CONJUGATION | Genes involved in Glutathione conjugation |
0.2 | 2.1 | REACTOME THE NLRP3 INFLAMMASOME | Genes involved in The NLRP3 inflammasome |
0.2 | 6.9 | REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D | Genes involved in Metabolism of steroid hormones and vitamins A and D |
0.1 | 1.3 | REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY | Genes involved in Regulation of the Fanconi anemia pathway |
0.1 | 2.6 | REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX | Genes involved in Degradation of the extracellular matrix |
0.1 | 3.4 | REACTOME RECYCLING PATHWAY OF L1 | Genes involved in Recycling pathway of L1 |
0.1 | 11.0 | REACTOME PEPTIDE LIGAND BINDING RECEPTORS | Genes involved in Peptide ligand-binding receptors |
0.1 | 0.4 | REACTOME HORMONE LIGAND BINDING RECEPTORS | Genes involved in Hormone ligand-binding receptors |
0.1 | 0.9 | REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS | Genes involved in Facilitative Na+-independent glucose transporters |
0.1 | 1.3 | REACTOME CHOLESTEROL BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
0.0 | 4.7 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
0.0 | 1.1 | REACTOME EGFR DOWNREGULATION | Genes involved in EGFR downregulation |
0.0 | 1.8 | REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION | Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression |
0.0 | 0.7 | REACTOME REGULATION OF KIT SIGNALING | Genes involved in Regulation of KIT signaling |
0.0 | 0.7 | REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY | Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery |
0.0 | 0.9 | REACTOME MYOGENESIS | Genes involved in Myogenesis |
0.0 | 3.9 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
0.0 | 2.8 | REACTOME TRANSLATION | Genes involved in Translation |