avrg: GSE58827: Dynamics of the Mouse Liver
Gene Symbol | Gene ID | Gene Info |
---|---|---|
Nkx2-5
|
ENSMUSG00000015579.4 | NK2 homeobox 5 |
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Nkx2-5 | mm10_v2_chr17_-_26841565_26841591 | 0.36 | 3.3e-02 | Click! |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.2 | 18.7 | GO:0031000 | response to caffeine(GO:0031000) |
0.7 | 4.0 | GO:2000987 | positive regulation of fear response(GO:1903367) positive regulation of behavioral fear response(GO:2000987) |
0.6 | 2.9 | GO:0002803 | positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803) |
0.2 | 0.7 | GO:1902617 | response to fluoride(GO:1902617) |
0.2 | 0.8 | GO:0060907 | positive regulation of macrophage cytokine production(GO:0060907) |
0.2 | 0.8 | GO:0031296 | B cell costimulation(GO:0031296) |
0.2 | 0.5 | GO:0045204 | MAPK export from nucleus(GO:0045204) |
0.2 | 0.7 | GO:0071374 | positive regulation of anagen(GO:0051885) cellular response to parathyroid hormone stimulus(GO:0071374) |
0.2 | 0.5 | GO:0021589 | hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589) |
0.1 | 0.5 | GO:0034638 | phosphatidylcholine catabolic process(GO:0034638) |
0.1 | 1.1 | GO:0008228 | opsonization(GO:0008228) |
0.1 | 17.1 | GO:0007586 | digestion(GO:0007586) |
0.1 | 1.3 | GO:0035878 | nail development(GO:0035878) |
0.1 | 0.4 | GO:0060830 | ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830) |
0.1 | 0.5 | GO:2000304 | positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304) |
0.1 | 0.2 | GO:0014718 | positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718) myoblast development(GO:0048627) |
0.1 | 0.5 | GO:0038031 | non-canonical Wnt signaling pathway via JNK cascade(GO:0038031) |
0.1 | 1.0 | GO:0001778 | plasma membrane repair(GO:0001778) |
0.1 | 1.1 | GO:2000810 | regulation of bicellular tight junction assembly(GO:2000810) |
0.1 | 3.1 | GO:1900026 | positive regulation of substrate adhesion-dependent cell spreading(GO:1900026) |
0.1 | 0.3 | GO:1904587 | response to glycoprotein(GO:1904587) |
0.1 | 0.5 | GO:0071732 | cellular response to nitric oxide(GO:0071732) |
0.1 | 0.8 | GO:0070493 | thrombin receptor signaling pathway(GO:0070493) |
0.0 | 0.3 | GO:0090306 | spindle assembly involved in meiosis(GO:0090306) |
0.0 | 0.5 | GO:0007128 | meiotic prophase I(GO:0007128) prophase(GO:0051324) |
0.0 | 2.9 | GO:0007585 | respiratory gaseous exchange(GO:0007585) |
0.0 | 0.4 | GO:0051791 | medium-chain fatty acid metabolic process(GO:0051791) |
0.0 | 0.2 | GO:0010991 | negative regulation of SMAD protein complex assembly(GO:0010991) |
0.0 | 0.5 | GO:0090110 | cargo loading into COPII-coated vesicle(GO:0090110) |
0.0 | 0.3 | GO:0036295 | cellular response to increased oxygen levels(GO:0036295) |
0.0 | 0.4 | GO:0002862 | negative regulation of inflammatory response to antigenic stimulus(GO:0002862) |
0.0 | 0.3 | GO:0070072 | vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072) |
0.0 | 0.2 | GO:0030242 | pexophagy(GO:0030242) |
0.0 | 0.4 | GO:0090161 | Golgi ribbon formation(GO:0090161) |
0.0 | 0.2 | GO:2000232 | regulation of rRNA processing(GO:2000232) |
0.0 | 0.1 | GO:0061026 | septum secundum development(GO:0003285) cardiac muscle tissue regeneration(GO:0061026) negative regulation of connective tissue replacement(GO:1905204) |
0.0 | 0.2 | GO:0001574 | ganglioside biosynthetic process(GO:0001574) |
0.0 | 0.2 | GO:0030579 | ubiquitin-dependent SMAD protein catabolic process(GO:0030579) |
0.0 | 0.2 | GO:2000096 | positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096) |
0.0 | 36.0 | GO:0006508 | proteolysis(GO:0006508) |
0.0 | 0.9 | GO:0007019 | microtubule depolymerization(GO:0007019) |
0.0 | 0.3 | GO:0048172 | regulation of short-term neuronal synaptic plasticity(GO:0048172) |
0.0 | 0.2 | GO:0010623 | apoptotic DNA fragmentation(GO:0006309) programmed cell death involved in cell development(GO:0010623) |
0.0 | 0.8 | GO:0007528 | neuromuscular junction development(GO:0007528) |
0.0 | 0.3 | GO:0019731 | antibacterial humoral response(GO:0019731) |
0.0 | 0.4 | GO:0071385 | cellular response to glucocorticoid stimulus(GO:0071385) |
0.0 | 0.5 | GO:0006829 | zinc II ion transport(GO:0006829) |
0.0 | 0.3 | GO:0032467 | positive regulation of cytokinesis(GO:0032467) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.0 | 4.0 | GO:0032280 | symmetric synapse(GO:0032280) |
0.2 | 2.9 | GO:0097208 | alveolar lamellar body(GO:0097208) |
0.2 | 2.9 | GO:0042581 | specific granule(GO:0042581) |
0.1 | 1.0 | GO:0005826 | actomyosin contractile ring(GO:0005826) |
0.1 | 1.3 | GO:0030056 | hemidesmosome(GO:0030056) |
0.0 | 0.4 | GO:0030991 | intraciliary transport particle A(GO:0030991) |
0.0 | 0.7 | GO:0034366 | spherical high-density lipoprotein particle(GO:0034366) |
0.0 | 0.3 | GO:0000137 | Golgi cis cisterna(GO:0000137) |
0.0 | 69.2 | GO:0005615 | extracellular space(GO:0005615) |
0.0 | 0.2 | GO:0001651 | dense fibrillar component(GO:0001651) |
0.0 | 0.5 | GO:0030127 | COPII vesicle coat(GO:0030127) |
0.0 | 0.3 | GO:0033180 | proton-transporting V-type ATPase, V1 domain(GO:0033180) |
0.0 | 0.9 | GO:0035371 | microtubule plus-end(GO:0035371) |
0.0 | 0.2 | GO:0045252 | oxoglutarate dehydrogenase complex(GO:0045252) |
0.0 | 0.6 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.0 | 30.6 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
0.6 | 4.0 | GO:0001515 | opioid peptide activity(GO:0001515) |
0.2 | 0.7 | GO:0004063 | aryldialkylphosphatase activity(GO:0004063) |
0.2 | 1.1 | GO:0038181 | bile acid receptor activity(GO:0038181) |
0.2 | 43.2 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
0.2 | 0.8 | GO:0015057 | thrombin receptor activity(GO:0015057) |
0.2 | 1.3 | GO:0038132 | neuregulin binding(GO:0038132) |
0.1 | 0.5 | GO:0030250 | cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250) |
0.1 | 2.9 | GO:0004190 | aspartic-type endopeptidase activity(GO:0004190) |
0.1 | 0.4 | GO:0004994 | somatostatin receptor activity(GO:0004994) |
0.1 | 0.5 | GO:0004977 | melanocortin receptor activity(GO:0004977) |
0.1 | 0.5 | GO:0004528 | phosphodiesterase I activity(GO:0004528) |
0.1 | 0.5 | GO:0047499 | calcium-independent phospholipase A2 activity(GO:0047499) |
0.0 | 0.8 | GO:0038191 | neuropilin binding(GO:0038191) |
0.0 | 0.4 | GO:0016406 | carnitine O-acyltransferase activity(GO:0016406) |
0.0 | 0.6 | GO:0015250 | water channel activity(GO:0015250) |
0.0 | 0.2 | GO:0042134 | rRNA primary transcript binding(GO:0042134) |
0.0 | 0.3 | GO:0061676 | importin-alpha family protein binding(GO:0061676) |
0.0 | 0.1 | GO:0000700 | mismatch base pair DNA N-glycosylase activity(GO:0000700) |
0.0 | 0.3 | GO:0001665 | alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665) |
0.0 | 0.6 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
0.0 | 0.2 | GO:0004591 | oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591) |
0.0 | 0.2 | GO:0008467 | [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467) |
0.0 | 0.2 | GO:0048495 | Roundabout binding(GO:0048495) |
0.0 | 0.5 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
0.0 | 0.3 | GO:0016500 | protein-hormone receptor activity(GO:0016500) |
0.0 | 0.7 | GO:0005109 | frizzled binding(GO:0005109) |
0.0 | 0.1 | GO:0016494 | C-X-C chemokine receptor activity(GO:0016494) |
0.0 | 0.5 | GO:0001223 | transcription coactivator binding(GO:0001223) |
0.0 | 0.5 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
0.0 | 0.3 | GO:0046961 | proton-transporting ATPase activity, rotational mechanism(GO:0046961) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 8.2 | PID UPA UPAR PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
0.1 | 1.3 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
0.1 | 18.7 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
0.0 | 0.8 | PID THROMBIN PAR4 PATHWAY | PAR4-mediated thrombin signaling events |
0.0 | 3.5 | PID AP1 PATHWAY | AP-1 transcription factor network |
0.0 | 1.1 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
0.0 | 1.0 | PID INTEGRIN A4B1 PATHWAY | Alpha4 beta1 integrin signaling events |
0.0 | 3.7 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
0.0 | 0.5 | PID HDAC CLASSIII PATHWAY | Signaling events mediated by HDAC Class III |
0.0 | 0.5 | PID WNT SIGNALING PATHWAY | Wnt signaling network |
0.0 | 0.5 | PID LIS1 PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.7 | 18.7 | REACTOME DEFENSINS | Genes involved in Defensins |
0.0 | 0.6 | REACTOME PASSIVE TRANSPORT BY AQUAPORINS | Genes involved in Passive Transport by Aquaporins |
0.0 | 0.3 | REACTOME HORMONE LIGAND BINDING RECEPTORS | Genes involved in Hormone ligand-binding receptors |
0.0 | 5.9 | REACTOME PEPTIDE LIGAND BINDING RECEPTORS | Genes involved in Peptide ligand-binding receptors |
0.0 | 0.8 | REACTOME OTHER SEMAPHORIN INTERACTIONS | Genes involved in Other semaphorin interactions |
0.0 | 0.8 | REACTOME ACYL CHAIN REMODELLING OF PE | Genes involved in Acyl chain remodelling of PE |
0.0 | 0.4 | REACTOME P2Y RECEPTORS | Genes involved in P2Y receptors |
0.0 | 0.4 | REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS | Genes involved in Proteolytic cleavage of SNARE complex proteins |
0.0 | 0.5 | REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC | Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC |
0.0 | 0.5 | REACTOME ZINC TRANSPORTERS | Genes involved in Zinc transporters |
0.0 | 1.1 | REACTOME G ALPHA S SIGNALLING EVENTS | Genes involved in G alpha (s) signalling events |
0.0 | 0.1 | REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY | Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway |
0.0 | 0.4 | REACTOME PEROXISOMAL LIPID METABOLISM | Genes involved in Peroxisomal lipid metabolism |
0.0 | 0.6 | REACTOME NCAM1 INTERACTIONS | Genes involved in NCAM1 interactions |
0.0 | 1.3 | REACTOME INTEGRIN CELL SURFACE INTERACTIONS | Genes involved in Integrin cell surface interactions |
0.0 | 0.3 | REACTOME INSULIN RECEPTOR RECYCLING | Genes involved in Insulin receptor recycling |
0.0 | 1.2 | REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |