avrg: GSE58827: Dynamics of the Mouse Liver
Name | miRBASE accession |
---|---|
mmu-miR-142a-3p.1
|
MIMAT0000155 |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 1.8 | GO:0007525 | somatic muscle development(GO:0007525) |
0.3 | 1.0 | GO:0035526 | retrograde transport, plasma membrane to Golgi(GO:0035526) |
0.3 | 0.9 | GO:1905223 | epicardium morphogenesis(GO:1905223) |
0.3 | 1.1 | GO:2000721 | positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721) |
0.2 | 1.2 | GO:0072383 | plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386) |
0.2 | 0.9 | GO:0001827 | inner cell mass cell fate commitment(GO:0001827) |
0.2 | 0.7 | GO:0045715 | negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715) |
0.2 | 1.2 | GO:2000211 | regulation of glutamate metabolic process(GO:2000211) |
0.2 | 1.4 | GO:0030242 | pexophagy(GO:0030242) |
0.2 | 1.0 | GO:0035977 | protein deglycosylation involved in glycoprotein catabolic process(GO:0035977) protein demannosylation(GO:0036507) protein alpha-1,2-demannosylation(GO:0036508) glycoprotein ERAD pathway(GO:0097466) mannose trimming involved in glycoprotein ERAD pathway(GO:1904382) |
0.2 | 1.3 | GO:0051775 | response to redox state(GO:0051775) negative regulation of glucocorticoid receptor signaling pathway(GO:2000323) |
0.2 | 1.0 | GO:1900170 | negative regulation of glucocorticoid mediated signaling pathway(GO:1900170) |
0.2 | 0.5 | GO:1904742 | regulation of telomeric DNA binding(GO:1904742) |
0.1 | 0.5 | GO:1900740 | regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740) |
0.1 | 0.6 | GO:0018076 | N-terminal peptidyl-lysine acetylation(GO:0018076) |
0.1 | 0.3 | GO:1990859 | cellular response to endothelin(GO:1990859) |
0.1 | 0.5 | GO:0000117 | regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117) |
0.1 | 0.6 | GO:0060708 | spongiotrophoblast differentiation(GO:0060708) |
0.1 | 0.7 | GO:0045900 | negative regulation of translational elongation(GO:0045900) |
0.1 | 0.6 | GO:0035331 | negative regulation of hippo signaling(GO:0035331) |
0.1 | 0.6 | GO:0000056 | ribosomal small subunit export from nucleus(GO:0000056) |
0.1 | 0.2 | GO:1902256 | endocardial cushion fusion(GO:0003274) apoptotic process involved in outflow tract morphogenesis(GO:0003275) ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910) positive regulation of catagen(GO:0051795) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256) |
0.1 | 0.3 | GO:1903347 | negative regulation of bicellular tight junction assembly(GO:1903347) |
0.1 | 0.4 | GO:0072092 | ureteric bud invasion(GO:0072092) |
0.1 | 0.7 | GO:0006824 | cobalt ion transport(GO:0006824) |
0.1 | 0.3 | GO:0032915 | positive regulation of transforming growth factor beta2 production(GO:0032915) |
0.1 | 0.5 | GO:2000601 | positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601) |
0.1 | 0.2 | GO:0046881 | positive regulation of follicle-stimulating hormone secretion(GO:0046881) |
0.1 | 0.5 | GO:0016554 | cytidine to uridine editing(GO:0016554) |
0.1 | 0.7 | GO:0033147 | negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147) |
0.1 | 0.4 | GO:0045345 | MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343) positive regulation of MHC class I biosynthetic process(GO:0045345) positive regulation of MHC class II biosynthetic process(GO:0045348) |
0.1 | 0.3 | GO:0030950 | establishment or maintenance of actin cytoskeleton polarity(GO:0030950) |
0.1 | 1.3 | GO:0045116 | protein neddylation(GO:0045116) |
0.0 | 0.4 | GO:1903551 | regulation of extracellular exosome assembly(GO:1903551) |
0.0 | 0.5 | GO:0042989 | sequestering of actin monomers(GO:0042989) |
0.0 | 0.1 | GO:1903919 | regulation of actin filament severing(GO:1903918) negative regulation of actin filament severing(GO:1903919) |
0.0 | 0.1 | GO:0070104 | negative regulation of interleukin-6-mediated signaling pathway(GO:0070104) |
0.0 | 0.1 | GO:0002270 | plasmacytoid dendritic cell activation(GO:0002270) |
0.0 | 0.4 | GO:0043569 | negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569) |
0.0 | 0.3 | GO:0071557 | histone H3-K27 demethylation(GO:0071557) |
0.0 | 0.1 | GO:0032470 | positive regulation of endoplasmic reticulum calcium ion concentration(GO:0032470) |
0.0 | 0.2 | GO:1901907 | diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911) |
0.0 | 0.7 | GO:0006622 | protein targeting to lysosome(GO:0006622) |
0.0 | 0.8 | GO:0008210 | estrogen metabolic process(GO:0008210) |
0.0 | 0.6 | GO:0007250 | activation of NF-kappaB-inducing kinase activity(GO:0007250) |
0.0 | 0.1 | GO:0046726 | positive regulation by virus of viral protein levels in host cell(GO:0046726) |
0.0 | 0.4 | GO:0010839 | negative regulation of keratinocyte proliferation(GO:0010839) |
0.0 | 0.3 | GO:0048752 | semicircular canal morphogenesis(GO:0048752) |
0.0 | 0.3 | GO:1901898 | negative regulation of relaxation of cardiac muscle(GO:1901898) |
0.0 | 0.1 | GO:1904684 | negative regulation of metalloendopeptidase activity(GO:1904684) |
0.0 | 0.4 | GO:0043968 | histone H2A acetylation(GO:0043968) |
0.0 | 0.2 | GO:0050861 | positive regulation of B cell receptor signaling pathway(GO:0050861) |
0.0 | 0.2 | GO:1900827 | positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827) |
0.0 | 0.6 | GO:0060009 | Sertoli cell development(GO:0060009) |
0.0 | 0.2 | GO:2000074 | regulation of type B pancreatic cell development(GO:2000074) |
0.0 | 0.6 | GO:0015813 | L-glutamate transport(GO:0015813) |
0.0 | 0.1 | GO:0060382 | release from viral latency(GO:0019046) regulation of DNA strand elongation(GO:0060382) |
0.0 | 0.2 | GO:0032119 | sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088) |
0.0 | 0.1 | GO:0061763 | multivesicular body-lysosome fusion(GO:0061763) |
0.0 | 0.1 | GO:0006621 | protein retention in ER lumen(GO:0006621) |
0.0 | 0.3 | GO:0043248 | proteasome assembly(GO:0043248) |
0.0 | 0.1 | GO:0030043 | actin filament fragmentation(GO:0030043) |
0.0 | 0.2 | GO:0060613 | fat pad development(GO:0060613) |
0.0 | 0.6 | GO:0032967 | positive regulation of collagen biosynthetic process(GO:0032967) |
0.0 | 0.3 | GO:0021800 | cerebral cortex tangential migration(GO:0021800) |
0.0 | 0.1 | GO:1903691 | positive regulation of wound healing, spreading of epidermal cells(GO:1903691) |
0.0 | 0.4 | GO:0030866 | cortical actin cytoskeleton organization(GO:0030866) |
0.0 | 0.5 | GO:0003333 | amino acid transmembrane transport(GO:0003333) |
0.0 | 0.0 | GO:1902630 | regulation of membrane hyperpolarization(GO:1902630) |
0.0 | 0.5 | GO:0046854 | phosphatidylinositol phosphorylation(GO:0046854) |
0.0 | 0.3 | GO:0051457 | maintenance of protein location in nucleus(GO:0051457) |
0.0 | 0.1 | GO:0090206 | negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206) |
0.0 | 0.1 | GO:0045176 | apical protein localization(GO:0045176) |
0.0 | 0.2 | GO:0043517 | positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) |
0.0 | 0.4 | GO:0008333 | endosome to lysosome transport(GO:0008333) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 0.7 | GO:0034685 | integrin alphav-beta5 complex(GO:0034684) integrin alphav-beta6 complex(GO:0034685) |
0.2 | 1.2 | GO:0034750 | Scrib-APC-beta-catenin complex(GO:0034750) |
0.1 | 0.9 | GO:0005726 | perichromatin fibrils(GO:0005726) |
0.1 | 1.1 | GO:0032591 | dendritic spine membrane(GO:0032591) |
0.1 | 0.7 | GO:0031313 | extrinsic component of endosome membrane(GO:0031313) |
0.1 | 0.2 | GO:0034673 | inhibin-betaglycan-ActRII complex(GO:0034673) |
0.1 | 1.5 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
0.1 | 0.5 | GO:0030478 | actin cap(GO:0030478) |
0.1 | 0.6 | GO:0005642 | annulate lamellae(GO:0005642) |
0.1 | 1.0 | GO:0031527 | filopodium membrane(GO:0031527) |
0.1 | 0.7 | GO:0072546 | ER membrane protein complex(GO:0072546) |
0.0 | 0.1 | GO:0005900 | oncostatin-M receptor complex(GO:0005900) |
0.0 | 0.3 | GO:0031467 | Cul7-RING ubiquitin ligase complex(GO:0031467) |
0.0 | 0.8 | GO:0098563 | integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563) |
0.0 | 0.6 | GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671) |
0.0 | 0.7 | GO:0035253 | ciliary rootlet(GO:0035253) |
0.0 | 0.1 | GO:0070381 | endosome to plasma membrane transport vesicle(GO:0070381) |
0.0 | 0.7 | GO:1990124 | messenger ribonucleoprotein complex(GO:1990124) |
0.0 | 0.5 | GO:0097431 | mitotic spindle pole(GO:0097431) |
0.0 | 0.3 | GO:0044666 | MLL3/4 complex(GO:0044666) |
0.0 | 0.3 | GO:0008541 | proteasome regulatory particle, lid subcomplex(GO:0008541) |
0.0 | 0.4 | GO:0033391 | chromatoid body(GO:0033391) |
0.0 | 0.3 | GO:0031616 | spindle pole centrosome(GO:0031616) |
0.0 | 0.4 | GO:0005652 | nuclear lamina(GO:0005652) |
0.0 | 0.4 | GO:0016580 | Sin3 complex(GO:0016580) |
0.0 | 1.0 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
0.0 | 0.3 | GO:0031932 | TORC2 complex(GO:0031932) |
0.0 | 0.3 | GO:0000930 | gamma-tubulin complex(GO:0000930) |
0.0 | 0.4 | GO:0070971 | endoplasmic reticulum exit site(GO:0070971) |
0.0 | 0.1 | GO:0031254 | uropod(GO:0001931) cell trailing edge(GO:0031254) |
0.0 | 0.1 | GO:0097208 | alveolar lamellar body(GO:0097208) |
0.0 | 0.2 | GO:0005662 | DNA replication factor A complex(GO:0005662) |
0.0 | 0.2 | GO:0014731 | spectrin-associated cytoskeleton(GO:0014731) |
0.0 | 0.9 | GO:0000922 | spindle pole(GO:0000922) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 1.0 | GO:0004883 | glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051) |
0.1 | 0.7 | GO:0019960 | C-X3-C chemokine binding(GO:0019960) |
0.1 | 1.1 | GO:0005114 | type II transforming growth factor beta receptor binding(GO:0005114) |
0.1 | 1.0 | GO:0004571 | mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) |
0.1 | 0.7 | GO:0099609 | microtubule lateral binding(GO:0099609) |
0.1 | 0.6 | GO:0004468 | lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468) |
0.1 | 0.7 | GO:0015087 | cobalt ion transmembrane transporter activity(GO:0015087) |
0.1 | 1.2 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
0.1 | 0.6 | GO:0005049 | nuclear export signal receptor activity(GO:0005049) |
0.1 | 1.6 | GO:0097602 | cullin family protein binding(GO:0097602) |
0.1 | 1.0 | GO:0017166 | vinculin binding(GO:0017166) |
0.1 | 1.9 | GO:0000062 | fatty-acyl-CoA binding(GO:0000062) |
0.0 | 0.9 | GO:0000900 | translation repressor activity, nucleic acid binding(GO:0000900) |
0.0 | 0.6 | GO:0005314 | high-affinity glutamate transmembrane transporter activity(GO:0005314) |
0.0 | 0.1 | GO:0004923 | interleukin-6 receptor activity(GO:0004915) leukemia inhibitory factor receptor activity(GO:0004923) interleukin-6 binding(GO:0019981) |
0.0 | 0.4 | GO:0017162 | aryl hydrocarbon receptor binding(GO:0017162) |
0.0 | 0.1 | GO:0000401 | open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402) |
0.0 | 0.3 | GO:0071558 | histone demethylase activity (H3-K27 specific)(GO:0071558) |
0.0 | 1.5 | GO:0008536 | Ran GTPase binding(GO:0008536) |
0.0 | 0.2 | GO:0034431 | endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) |
0.0 | 0.5 | GO:0001206 | transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206) |
0.0 | 0.7 | GO:0070016 | armadillo repeat domain binding(GO:0070016) |
0.0 | 0.1 | GO:0046923 | ER retention sequence binding(GO:0046923) |
0.0 | 0.2 | GO:0005173 | stem cell factor receptor binding(GO:0005173) |
0.0 | 0.8 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
0.0 | 0.7 | GO:0070530 | K63-linked polyubiquitin binding(GO:0070530) |
0.0 | 0.2 | GO:0017002 | activin-activated receptor activity(GO:0017002) |
0.0 | 1.0 | GO:0001671 | ATPase activator activity(GO:0001671) |
0.0 | 1.2 | GO:0070888 | E-box binding(GO:0070888) |
0.0 | 0.3 | GO:0035497 | cAMP response element binding(GO:0035497) |
0.0 | 0.1 | GO:0097506 | uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506) |
0.0 | 0.4 | GO:0042043 | neurexin family protein binding(GO:0042043) |
0.0 | 0.5 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
0.0 | 0.9 | GO:0030331 | estrogen receptor binding(GO:0030331) |
0.0 | 0.8 | GO:0019003 | GDP binding(GO:0019003) |
0.0 | 0.5 | GO:0042162 | telomeric DNA binding(GO:0042162) |
0.0 | 0.4 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
0.0 | 0.1 | GO:1990430 | extracellular matrix protein binding(GO:1990430) |
0.0 | 0.5 | GO:0003785 | actin monomer binding(GO:0003785) |
0.0 | 0.2 | GO:0042171 | lysophosphatidic acid acyltransferase activity(GO:0042171) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 1.6 | PID INTEGRIN5 PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
0.1 | 1.3 | PID CIRCADIAN PATHWAY | Circadian rhythm pathway |
0.0 | 1.2 | PID BETA CATENIN DEG PATHWAY | Degradation of beta catenin |
0.0 | 1.1 | PID INTEGRIN CS PATHWAY | Integrin family cell surface interactions |
0.0 | 0.6 | PID RANBP2 PATHWAY | Sumoylation by RanBP2 regulates transcriptional repression |
0.0 | 0.4 | PID ECADHERIN KERATINOCYTE PATHWAY | E-cadherin signaling in keratinocytes |
0.0 | 0.4 | PID SYNDECAN 3 PATHWAY | Syndecan-3-mediated signaling events |
0.0 | 0.3 | PID TCR JNK PATHWAY | JNK signaling in the CD4+ TCR pathway |
0.0 | 0.6 | PID P38 MKK3 6PATHWAY | p38 MAPK signaling pathway |
0.0 | 0.9 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
0.0 | 0.2 | SA MMP CYTOKINE CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
0.0 | 1.0 | PID HDAC CLASSII PATHWAY | Signaling events mediated by HDAC Class II |
0.0 | 0.6 | PID NCADHERIN PATHWAY | N-cadherin signaling events |
0.0 | 0.4 | PID HDAC CLASSIII PATHWAY | Signaling events mediated by HDAC Class III |
0.0 | 0.5 | PID ILK PATHWAY | Integrin-linked kinase signaling |
0.0 | 0.5 | PID ARF6 PATHWAY | Arf6 signaling events |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 1.0 | REACTOME CALNEXIN CALRETICULIN CYCLE | Genes involved in Calnexin/calreticulin cycle |
0.1 | 0.7 | REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION | Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation |
0.1 | 1.2 | REACTOME CTNNB1 PHOSPHORYLATION CASCADE | Genes involved in Beta-catenin phosphorylation cascade |
0.1 | 1.5 | REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING | Genes involved in Downregulation of TGF-beta receptor signaling |
0.0 | 2.3 | REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION | Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression |
0.0 | 0.6 | REACTOME NOTCH HLH TRANSCRIPTION PATHWAY | Genes involved in Notch-HLH transcription pathway |
0.0 | 0.9 | REACTOME INSULIN SYNTHESIS AND PROCESSING | Genes involved in Insulin Synthesis and Processing |
0.0 | 0.7 | REACTOME PECAM1 INTERACTIONS | Genes involved in PECAM1 interactions |
0.0 | 0.9 | REACTOME SIGNALING BY HIPPO | Genes involved in Signaling by Hippo |
0.0 | 0.5 | REACTOME DCC MEDIATED ATTRACTIVE SIGNALING | Genes involved in DCC mediated attractive signaling |
0.0 | 0.3 | REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS | Genes involved in p130Cas linkage to MAPK signaling for integrins |
0.0 | 0.7 | REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |
0.0 | 0.5 | REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT | Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT) |
0.0 | 0.3 | REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS | Genes involved in Activation of the AP-1 family of transcription factors |
0.0 | 0.3 | REACTOME ACTIVATION OF BH3 ONLY PROTEINS | Genes involved in Activation of BH3-only proteins |
0.0 | 0.1 | REACTOME REGULATION OF KIT SIGNALING | Genes involved in Regulation of KIT signaling |
0.0 | 0.1 | REACTOME SPRY REGULATION OF FGF SIGNALING | Genes involved in Spry regulation of FGF signaling |
0.0 | 1.2 | REACTOME INTEGRIN CELL SURFACE INTERACTIONS | Genes involved in Integrin cell surface interactions |
0.0 | 0.2 | REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK | Genes involved in Regulation of Rheb GTPase activity by AMPK |
0.0 | 0.1 | REACTOME IL 6 SIGNALING | Genes involved in Interleukin-6 signaling |
0.0 | 0.1 | REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING | Genes involved in Advanced glycosylation endproduct receptor signaling |
0.0 | 0.5 | REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
0.0 | 0.2 | REACTOME SIGNALING BY NODAL | Genes involved in Signaling by NODAL |