avrg: GSE58827: Dynamics of the Mouse Liver
Gene Symbol | Gene ID | Gene Info |
---|---|---|
Rxra
|
ENSMUSG00000015846.8 | retinoid X receptor alpha |
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Rxra | mm10_v2_chr2_+_27677201_27677229 | 0.12 | 4.9e-01 | Click! |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.3 | 5.0 | GO:0010982 | regulation of high-density lipoprotein particle clearance(GO:0010982) |
1.0 | 3.9 | GO:0006069 | ethanol oxidation(GO:0006069) |
0.8 | 5.0 | GO:0033540 | fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540) |
0.4 | 1.3 | GO:0071929 | alpha-tubulin acetylation(GO:0071929) |
0.4 | 1.7 | GO:0036367 | adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367) |
0.4 | 2.6 | GO:0006145 | purine nucleobase catabolic process(GO:0006145) |
0.3 | 4.9 | GO:0043589 | Notch receptor processing(GO:0007220) skin morphogenesis(GO:0043589) |
0.3 | 10.4 | GO:0019373 | epoxygenase P450 pathway(GO:0019373) |
0.3 | 0.9 | GO:0010845 | positive regulation of reciprocal meiotic recombination(GO:0010845) |
0.3 | 0.9 | GO:0019405 | alditol catabolic process(GO:0019405) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166) |
0.3 | 0.9 | GO:0034959 | substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959) |
0.3 | 1.3 | GO:0033140 | negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140) |
0.3 | 2.3 | GO:1901162 | serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162) |
0.2 | 0.6 | GO:0019389 | glucuronoside metabolic process(GO:0019389) |
0.2 | 1.1 | GO:0032929 | negative regulation of superoxide anion generation(GO:0032929) |
0.2 | 1.7 | GO:0061727 | methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727) |
0.2 | 0.7 | GO:0071798 | response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799) |
0.2 | 1.1 | GO:1990416 | cellular response to brain-derived neurotrophic factor stimulus(GO:1990416) |
0.2 | 0.5 | GO:0031590 | wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591) |
0.1 | 1.6 | GO:0034626 | fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) |
0.1 | 1.2 | GO:0072602 | interleukin-4 secretion(GO:0072602) positive regulation of interleukin-2 secretion(GO:1900042) |
0.1 | 1.3 | GO:0030206 | chondroitin sulfate biosynthetic process(GO:0030206) |
0.1 | 0.4 | GO:0002296 | T-helper 1 cell lineage commitment(GO:0002296) |
0.1 | 0.3 | GO:0060392 | negative regulation of SMAD protein import into nucleus(GO:0060392) |
0.1 | 0.5 | GO:0002175 | protein localization to paranode region of axon(GO:0002175) |
0.1 | 1.4 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
0.1 | 0.4 | GO:0017182 | peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183) |
0.1 | 0.2 | GO:0032972 | regulation of muscle filament sliding speed(GO:0032972) |
0.1 | 1.3 | GO:0043518 | negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) |
0.1 | 0.3 | GO:0010901 | regulation of very-low-density lipoprotein particle remodeling(GO:0010901) |
0.1 | 1.2 | GO:1904294 | positive regulation of ERAD pathway(GO:1904294) |
0.1 | 1.8 | GO:0060285 | cilium or flagellum-dependent cell motility(GO:0001539) cilium-dependent cell motility(GO:0060285) |
0.1 | 0.2 | GO:0044208 | 'de novo' AMP biosynthetic process(GO:0044208) |
0.1 | 0.2 | GO:0015680 | intracellular copper ion transport(GO:0015680) |
0.1 | 0.2 | GO:0046618 | drug export(GO:0046618) |
0.1 | 0.3 | GO:1901668 | regulation of superoxide dismutase activity(GO:1901668) |
0.0 | 2.0 | GO:1900078 | positive regulation of cellular response to insulin stimulus(GO:1900078) |
0.0 | 1.7 | GO:0010758 | regulation of macrophage chemotaxis(GO:0010758) |
0.0 | 8.4 | GO:0098656 | anion transmembrane transport(GO:0098656) |
0.0 | 0.6 | GO:0043649 | dicarboxylic acid catabolic process(GO:0043649) |
0.0 | 0.7 | GO:0046485 | ether lipid metabolic process(GO:0046485) |
0.0 | 0.8 | GO:0010566 | regulation of ketone biosynthetic process(GO:0010566) |
0.0 | 1.3 | GO:0010257 | NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031) |
0.0 | 0.2 | GO:0033364 | mast cell secretory granule organization(GO:0033364) |
0.0 | 0.8 | GO:0007635 | chemosensory behavior(GO:0007635) |
0.0 | 0.4 | GO:0006337 | nucleosome disassembly(GO:0006337) |
0.0 | 0.7 | GO:0090201 | negative regulation of release of cytochrome c from mitochondria(GO:0090201) |
0.0 | 0.9 | GO:0019236 | response to pheromone(GO:0019236) |
0.0 | 1.3 | GO:0006953 | acute-phase response(GO:0006953) |
0.0 | 0.5 | GO:1900037 | regulation of cellular response to hypoxia(GO:1900037) |
0.0 | 0.2 | GO:0051418 | interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418) |
0.0 | 0.5 | GO:0001580 | detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580) |
0.0 | 0.1 | GO:1904717 | regulation of AMPA glutamate receptor clustering(GO:1904717) |
0.0 | 0.1 | GO:0030241 | skeletal muscle myosin thick filament assembly(GO:0030241) |
0.0 | 0.2 | GO:0042760 | very long-chain fatty acid catabolic process(GO:0042760) |
0.0 | 0.1 | GO:0070601 | centromeric sister chromatid cohesion(GO:0070601) |
0.0 | 0.3 | GO:0030150 | protein import into mitochondrial matrix(GO:0030150) |
0.0 | 0.3 | GO:2001179 | regulation of interleukin-10 secretion(GO:2001179) |
0.0 | 0.7 | GO:0045747 | positive regulation of Notch signaling pathway(GO:0045747) |
0.0 | 0.1 | GO:1901837 | negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837) |
0.0 | 5.2 | GO:0051321 | meiotic cell cycle(GO:0051321) |
0.0 | 0.5 | GO:0090200 | positive regulation of release of cytochrome c from mitochondria(GO:0090200) |
0.0 | 0.3 | GO:0036295 | cellular response to increased oxygen levels(GO:0036295) |
0.0 | 0.1 | GO:0071044 | histone mRNA catabolic process(GO:0071044) |
0.0 | 1.1 | GO:0006749 | glutathione metabolic process(GO:0006749) |
0.0 | 0.5 | GO:0032467 | positive regulation of cytokinesis(GO:0032467) |
0.0 | 0.2 | GO:0045838 | positive regulation of membrane potential(GO:0045838) |
0.0 | 1.3 | GO:0035725 | sodium ion transmembrane transport(GO:0035725) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 5.3 | GO:0034363 | intermediate-density lipoprotein particle(GO:0034363) |
0.2 | 4.9 | GO:0035253 | ciliary rootlet(GO:0035253) |
0.1 | 1.3 | GO:0097427 | microtubule bundle(GO:0097427) |
0.1 | 0.5 | GO:0097454 | Schwann cell microvillus(GO:0097454) |
0.1 | 1.7 | GO:0042622 | photoreceptor outer segment membrane(GO:0042622) |
0.1 | 0.3 | GO:0001405 | presequence translocase-associated import motor(GO:0001405) |
0.1 | 0.6 | GO:0045098 | type III intermediate filament(GO:0045098) |
0.1 | 0.9 | GO:0033093 | Weibel-Palade body(GO:0033093) |
0.1 | 1.4 | GO:0030056 | hemidesmosome(GO:0030056) |
0.1 | 0.3 | GO:1990130 | Iml1 complex(GO:1990130) |
0.1 | 1.8 | GO:0030992 | intraciliary transport particle B(GO:0030992) |
0.1 | 4.5 | GO:0005778 | peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903) |
0.0 | 0.7 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
0.0 | 0.2 | GO:0000931 | gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274) |
0.0 | 0.2 | GO:1990584 | cardiac Troponin complex(GO:1990584) |
0.0 | 1.8 | GO:0005747 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
0.0 | 1.3 | GO:0000407 | pre-autophagosomal structure(GO:0000407) |
0.0 | 0.3 | GO:0033180 | proton-transporting V-type ATPase, V1 domain(GO:0033180) |
0.0 | 0.4 | GO:0043083 | synaptic cleft(GO:0043083) |
0.0 | 0.6 | GO:0044438 | microbody part(GO:0044438) peroxisomal part(GO:0044439) |
0.0 | 0.2 | GO:0005786 | signal recognition particle, endoplasmic reticulum targeting(GO:0005786) |
0.0 | 0.4 | GO:0016514 | SWI/SNF complex(GO:0016514) |
0.0 | 0.2 | GO:0046581 | intercellular canaliculus(GO:0046581) |
0.0 | 1.6 | GO:0016529 | sarcoplasmic reticulum(GO:0016529) |
0.0 | 0.0 | GO:0055087 | Ski complex(GO:0055087) |
0.0 | 0.5 | GO:0051233 | desmosome(GO:0030057) spindle midzone(GO:0051233) |
0.0 | 0.1 | GO:0031415 | NatA complex(GO:0031415) |
0.0 | 0.8 | GO:0005776 | autophagosome(GO:0005776) |
0.0 | 1.6 | GO:0030176 | integral component of endoplasmic reticulum membrane(GO:0030176) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.5 | 9.1 | GO:0034875 | oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875) |
1.3 | 5.3 | GO:0070653 | high-density lipoprotein particle receptor binding(GO:0070653) |
1.3 | 3.9 | GO:0003960 | NADPH:quinone reductase activity(GO:0003960) alcohol dehydrogenase activity, zinc-dependent(GO:0004024) |
0.8 | 5.0 | GO:0016401 | palmitoyl-CoA oxidase activity(GO:0016401) |
0.6 | 4.9 | GO:0042500 | aspartic endopeptidase activity, intramembrane cleaving(GO:0042500) |
0.5 | 1.6 | GO:0008390 | testosterone 16-alpha-hydroxylase activity(GO:0008390) |
0.4 | 1.3 | GO:0000253 | 3-keto sterol reductase activity(GO:0000253) |
0.3 | 1.6 | GO:0016726 | xanthine dehydrogenase activity(GO:0004854) oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor(GO:0016726) |
0.3 | 1.7 | GO:0052650 | NADP-retinol dehydrogenase activity(GO:0052650) |
0.3 | 0.8 | GO:0070401 | NADP+ binding(GO:0070401) lithocholic acid binding(GO:1902121) |
0.2 | 1.3 | GO:0004468 | lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468) |
0.2 | 1.7 | GO:0004416 | hydroxyacylglutathione hydrolase activity(GO:0004416) |
0.2 | 0.5 | GO:0022850 | serotonin-gated cation channel activity(GO:0022850) |
0.2 | 0.7 | GO:0008169 | C-methyltransferase activity(GO:0008169) |
0.1 | 1.3 | GO:0015165 | pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165) |
0.1 | 1.6 | GO:0102338 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
0.1 | 0.4 | GO:0005136 | interleukin-4 receptor binding(GO:0005136) |
0.1 | 1.2 | GO:0001594 | trace-amine receptor activity(GO:0001594) |
0.1 | 1.1 | GO:0003993 | acid phosphatase activity(GO:0003993) |
0.1 | 3.6 | GO:0008391 | arachidonic acid monooxygenase activity(GO:0008391) |
0.1 | 1.3 | GO:0005436 | sodium:phosphate symporter activity(GO:0005436) |
0.1 | 0.9 | GO:0016861 | intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861) |
0.1 | 0.6 | GO:0008559 | xenobiotic-transporting ATPase activity(GO:0008559) |
0.1 | 0.8 | GO:0005432 | calcium:sodium antiporter activity(GO:0005432) |
0.1 | 0.2 | GO:0004466 | long-chain-acyl-CoA dehydrogenase activity(GO:0004466) very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099) |
0.1 | 0.5 | GO:0086080 | protein binding involved in heterotypic cell-cell adhesion(GO:0086080) |
0.1 | 0.6 | GO:0005391 | sodium:potassium-exchanging ATPase activity(GO:0005391) |
0.1 | 0.7 | GO:0034450 | ubiquitin-ubiquitin ligase activity(GO:0034450) |
0.1 | 0.6 | GO:0043024 | ribosomal small subunit binding(GO:0043024) |
0.1 | 0.7 | GO:0004955 | prostaglandin receptor activity(GO:0004955) |
0.0 | 0.2 | GO:0016842 | amidine-lyase activity(GO:0016842) |
0.0 | 9.8 | GO:0015293 | symporter activity(GO:0015293) |
0.0 | 1.4 | GO:0008137 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
0.0 | 0.3 | GO:0001515 | opioid peptide activity(GO:0001515) |
0.0 | 0.2 | GO:0043682 | copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682) |
0.0 | 0.9 | GO:0042800 | histone methyltransferase activity (H3-K4 specific)(GO:0042800) |
0.0 | 1.4 | GO:0030506 | ankyrin binding(GO:0030506) |
0.0 | 0.6 | GO:0019215 | intermediate filament binding(GO:0019215) |
0.0 | 0.2 | GO:0030942 | endoplasmic reticulum signal peptide binding(GO:0030942) |
0.0 | 0.2 | GO:0031013 | troponin I binding(GO:0031013) |
0.0 | 0.9 | GO:0016503 | pheromone receptor activity(GO:0016503) |
0.0 | 0.1 | GO:0004724 | magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724) |
0.0 | 0.1 | GO:0030160 | GKAP/Homer scaffold activity(GO:0030160) |
0.0 | 0.6 | GO:0016290 | palmitoyl-CoA hydrolase activity(GO:0016290) |
0.0 | 0.1 | GO:0051373 | FATZ binding(GO:0051373) |
0.0 | 1.1 | GO:0004364 | glutathione transferase activity(GO:0004364) |
0.0 | 2.0 | GO:0003707 | steroid hormone receptor activity(GO:0003707) |
0.0 | 2.3 | GO:0043130 | ubiquitin binding(GO:0043130) |
0.0 | 0.1 | GO:0004652 | polynucleotide adenylyltransferase activity(GO:0004652) |
0.0 | 1.8 | GO:0002039 | p53 binding(GO:0002039) |
0.0 | 0.4 | GO:0004029 | aldehyde dehydrogenase (NAD) activity(GO:0004029) |
0.0 | 0.2 | GO:0051011 | microtubule minus-end binding(GO:0051011) |
0.0 | 0.2 | GO:0015125 | bile acid transmembrane transporter activity(GO:0015125) |
0.0 | 1.8 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
0.0 | 0.4 | GO:0019707 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707) |
0.0 | 0.5 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
0.0 | 3.1 | GO:0061630 | ubiquitin protein ligase activity(GO:0061630) |
0.0 | 0.3 | GO:0046961 | proton-transporting ATPase activity, rotational mechanism(GO:0046961) |
0.0 | 0.4 | GO:0043395 | heparan sulfate proteoglycan binding(GO:0043395) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 4.9 | PID LKB1 PATHWAY | LKB1 signaling events |
0.0 | 1.1 | PID RHOA PATHWAY | RhoA signaling pathway |
0.0 | 0.5 | PID TRAIL PATHWAY | TRAIL signaling pathway |
0.0 | 0.6 | PID HIF2PATHWAY | HIF-2-alpha transcription factor network |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.7 | 9.8 | REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
0.6 | 3.9 | REACTOME ETHANOL OXIDATION | Genes involved in Ethanol oxidation |
0.3 | 4.9 | REACTOME REGULATED PROTEOLYSIS OF P75NTR | Genes involved in Regulated proteolysis of p75NTR |
0.3 | 5.6 | REACTOME ALPHA LINOLENIC ACID ALA METABOLISM | Genes involved in alpha-linolenic acid (ALA) metabolism |
0.3 | 5.3 | REACTOME HDL MEDIATED LIPID TRANSPORT | Genes involved in HDL-mediated lipid transport |
0.2 | 2.6 | REACTOME PURINE CATABOLISM | Genes involved in Purine catabolism |
0.1 | 1.3 | REACTOME GLUCURONIDATION | Genes involved in Glucuronidation |
0.1 | 0.6 | REACTOME ABACAVIR TRANSPORT AND METABOLISM | Genes involved in Abacavir transport and metabolism |
0.1 | 1.6 | REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS | Genes involved in Synthesis of very long-chain fatty acyl-CoAs |
0.1 | 0.7 | REACTOME PROSTANOID LIGAND RECEPTORS | Genes involved in Prostanoid ligand receptors |
0.1 | 1.3 | REACTOME CHOLESTEROL BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
0.1 | 1.1 | REACTOME RETROGRADE NEUROTROPHIN SIGNALLING | Genes involved in Retrograde neurotrophin signalling |
0.0 | 0.5 | REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS | Genes involved in Extrinsic Pathway for Apoptosis |
0.0 | 1.4 | REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS | Genes involved in Caspase-mediated cleavage of cytoskeletal proteins |
0.0 | 0.7 | REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY | Genes involved in Post-chaperonin tubulin folding pathway |
0.0 | 0.2 | REACTOME RECYCLING OF BILE ACIDS AND SALTS | Genes involved in Recycling of bile acids and salts |
0.0 | 2.0 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
0.0 | 0.9 | REACTOME GLYCOLYSIS | Genes involved in Glycolysis |
0.0 | 1.3 | REACTOME RESPIRATORY ELECTRON TRANSPORT | Genes involved in Respiratory electron transport |
0.0 | 0.5 | REACTOME LIGAND GATED ION CHANNEL TRANSPORT | Genes involved in Ligand-gated ion channel transport |
0.0 | 0.2 | REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES | Genes involved in Recruitment of NuMA to mitotic centrosomes |
0.0 | 1.1 | REACTOME METABOLISM OF VITAMINS AND COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
0.0 | 0.8 | REACTOME ION CHANNEL TRANSPORT | Genes involved in Ion channel transport |
0.0 | 0.2 | REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
0.0 | 0.9 | REACTOME MEIOTIC RECOMBINATION | Genes involved in Meiotic Recombination |
0.0 | 0.2 | REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION | Genes involved in Mitochondrial Fatty Acid Beta-Oxidation |
0.0 | 0.4 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
0.0 | 0.3 | REACTOME INSULIN RECEPTOR RECYCLING | Genes involved in Insulin receptor recycling |