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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for UGUGCUU

Z-value: 0.59

Motif logo

miRNA associated with seed UGUGCUU

NamemiRBASE accession
MIMAT0000663
MIMAT0027907

Activity profile of UGUGCUU motif

Sorted Z-values of UGUGCUU motif

Network of associatons between targets according to the STRING database.

First level regulatory network of UGUGCUU

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0032849 positive regulation of cellular pH reduction(GO:0032849) oligopeptide transmembrane transport(GO:0035672)
0.3 0.9 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.2 0.7 GO:0098928 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
0.2 0.7 GO:0007521 muscle cell fate determination(GO:0007521)
0.2 0.6 GO:0042275 error-free postreplication DNA repair(GO:0042275)
0.2 0.6 GO:0032916 positive regulation of transforming growth factor beta3 production(GO:0032916)
0.2 0.5 GO:0002270 plasmacytoid dendritic cell activation(GO:0002270)
0.1 0.4 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.1 0.5 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.1 0.4 GO:0003345 proepicardium cell migration involved in pericardium morphogenesis(GO:0003345)
0.1 0.5 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.1 0.4 GO:0018008 N-terminal peptidyl-glycine N-myristoylation(GO:0018008)
0.1 0.4 GO:0021836 chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) corticospinal neuron axon guidance through spinal cord(GO:0021972) positive regulation of negative chemotaxis(GO:0050924) induction of negative chemotaxis(GO:0050929) negative regulation of mononuclear cell migration(GO:0071676) negative regulation of retinal ganglion cell axon guidance(GO:0090260)
0.1 0.9 GO:0015919 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.1 0.8 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.1 0.3 GO:0021634 optic nerve formation(GO:0021634) optic chiasma development(GO:0061360) regulation of optic nerve formation(GO:2000595) positive regulation of optic nerve formation(GO:2000597)
0.1 0.4 GO:0035799 ureter maturation(GO:0035799) Peyer's patch morphogenesis(GO:0061146) positive regulation of metanephric glomerulus development(GO:0072300)
0.1 0.3 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.1 0.5 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.1 0.4 GO:0051586 positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
0.1 0.4 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.1 0.3 GO:0019072 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.1 0.5 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.1 0.3 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.1 0.4 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.1 0.3 GO:0031660 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662)
0.1 0.2 GO:0060821 inactivation of X chromosome by DNA methylation(GO:0060821)
0.1 0.5 GO:0042795 snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.1 0.3 GO:0021698 cerebellar cortex structural organization(GO:0021698)
0.1 0.5 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.1 0.9 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 0.2 GO:0031064 negative regulation of histone deacetylation(GO:0031064)
0.1 0.3 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.1 0.4 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.1 0.5 GO:0001955 blood vessel maturation(GO:0001955)
0.1 0.3 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.1 0.3 GO:1902608 negative regulation of inositol phosphate biosynthetic process(GO:0010920) regulation of large conductance calcium-activated potassium channel activity(GO:1902606) positive regulation of large conductance calcium-activated potassium channel activity(GO:1902608)
0.1 0.2 GO:0035621 ER to Golgi ceramide transport(GO:0035621)
0.1 0.5 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.1 0.4 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.1 0.2 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.1 0.2 GO:0061386 closure of optic fissure(GO:0061386)
0.1 1.5 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.1 0.3 GO:0009099 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.1 0.3 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1 0.4 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.1 0.2 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.1 0.5 GO:1903350 response to dopamine(GO:1903350) cellular response to dopamine(GO:1903351)
0.1 0.3 GO:0071692 protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694)
0.0 0.3 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.1 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.2 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.0 0.1 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 0.5 GO:0010459 negative regulation of heart rate(GO:0010459)
0.0 0.5 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0 0.3 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.1 GO:0071205 protein localization to juxtaparanode region of axon(GO:0071205)
0.0 0.7 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.7 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.0 0.2 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.3 GO:1903847 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.0 0.3 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.0 0.3 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.0 0.2 GO:0006477 protein sulfation(GO:0006477)
0.0 0.2 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
0.0 0.2 GO:0045054 constitutive secretory pathway(GO:0045054)
0.0 0.3 GO:0061502 early endosome to recycling endosome transport(GO:0061502)
0.0 0.2 GO:0035522 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0 0.1 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.0 1.1 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.4 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.0 0.3 GO:0030432 peristalsis(GO:0030432)
0.0 0.2 GO:0072718 response to cisplatin(GO:0072718)
0.0 0.3 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.0 0.4 GO:0014052 regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.0 1.0 GO:2000637 positive regulation of gene silencing by miRNA(GO:2000637)
0.0 0.3 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.0 0.3 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.0 0.5 GO:0060307 regulation of ventricular cardiac muscle cell membrane repolarization(GO:0060307)
0.0 0.1 GO:0019085 early viral transcription(GO:0019085)
0.0 0.9 GO:0030204 chondroitin sulfate metabolic process(GO:0030204)
0.0 0.3 GO:0045161 neuronal ion channel clustering(GO:0045161)
0.0 0.2 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.0 0.3 GO:2001135 regulation of endocytic recycling(GO:2001135)
0.0 0.5 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 1.7 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.0 0.2 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.2 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.2 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.0 0.2 GO:0002349 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.0 0.3 GO:2000582 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.6 GO:0060746 parental behavior(GO:0060746)
0.0 0.2 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.1 GO:1900095 regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.0 0.5 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 0.2 GO:0021778 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.0 0.5 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.0 GO:2000969 positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.0 0.2 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.1 GO:0006041 glucosamine metabolic process(GO:0006041)
0.0 0.4 GO:0090051 negative regulation of cell migration involved in sprouting angiogenesis(GO:0090051)
0.0 0.0 GO:0071374 cellular response to parathyroid hormone stimulus(GO:0071374)
0.0 0.1 GO:0009597 detection of virus(GO:0009597)
0.0 0.1 GO:0021631 optic nerve morphogenesis(GO:0021631)
0.0 0.1 GO:0036089 cleavage furrow formation(GO:0036089)
0.0 0.3 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.0 0.1 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.0 0.2 GO:1900746 regulation of vascular endothelial growth factor signaling pathway(GO:1900746)
0.0 0.1 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.0 0.2 GO:0031441 negative regulation of mRNA 3'-end processing(GO:0031441) negative regulation of mRNA catabolic process(GO:1902373)
0.0 0.2 GO:0030865 cortical cytoskeleton organization(GO:0030865)
0.0 0.3 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.0 GO:0038091 VEGF-activated platelet-derived growth factor receptor signaling pathway(GO:0038086) positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway(GO:0038091)
0.0 0.3 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.0 GO:0099527 postsynapse to nucleus signaling pathway(GO:0099527)
0.0 0.2 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
0.0 0.2 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.2 GO:0044336 canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.0 0.1 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.4 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0 0.3 GO:0042789 mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.0 0.4 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.2 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.2 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.2 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.3 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.6 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.1 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0 0.1 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0 0.2 GO:0097186 amelogenesis(GO:0097186)
0.0 0.0 GO:0033092 positive regulation of immature T cell proliferation in thymus(GO:0033092)
0.0 0.1 GO:1902748 melanocyte migration(GO:0097324) positive regulation of lens fiber cell differentiation(GO:1902748)
0.0 0.1 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:1990257 piccolo-bassoon transport vesicle(GO:1990257)
0.2 0.6 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.1 1.4 GO:0008290 F-actin capping protein complex(GO:0008290)
0.1 0.4 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.1 0.3 GO:0071203 WASH complex(GO:0071203)
0.1 0.2 GO:0034774 secretory granule lumen(GO:0034774) cytoplasmic membrane-bounded vesicle lumen(GO:0060205)
0.1 0.5 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.1 0.5 GO:0005827 polar microtubule(GO:0005827)
0.1 1.0 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1 0.5 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.5 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.1 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.0 0.3 GO:0001740 Barr body(GO:0001740)
0.0 0.2 GO:0032127 dense core granule membrane(GO:0032127)
0.0 0.2 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.1 GO:0042585 germinal vesicle(GO:0042585)
0.0 0.5 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.3 GO:0005638 lamin filament(GO:0005638)
0.0 0.3 GO:0031415 NatA complex(GO:0031415)
0.0 0.2 GO:0072487 MSL complex(GO:0072487)
0.0 0.1 GO:0098833 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835)
0.0 0.5 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.8 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.6 GO:0000145 exocyst(GO:0000145)
0.0 0.3 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.4 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.3 GO:0097227 sperm annulus(GO:0097227)
0.0 0.2 GO:0070695 FHF complex(GO:0070695)
0.0 0.2 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.2 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.2 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.2 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.1 GO:1902737 dendritic filopodium(GO:1902737)
0.0 0.2 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.2 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.2 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.5 GO:0010369 chromocenter(GO:0010369)
0.0 0.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.1 GO:0005584 collagen type I trimer(GO:0005584)
0.0 0.7 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.3 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.1 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.3 GO:0031143 pseudopodium(GO:0031143)
0.0 0.3 GO:0005922 connexon complex(GO:0005922)
0.0 0.5 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.1 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.2 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.1 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.0 0.3 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.6 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.3 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.2 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.6 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.1 GO:0030485 smooth muscle contractile fiber(GO:0030485)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.2 0.5 GO:0000402 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)
0.2 0.5 GO:0031208 POZ domain binding(GO:0031208)
0.2 1.2 GO:0004064 arylesterase activity(GO:0004064)
0.1 0.9 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 0.7 GO:0008934 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.1 0.4 GO:0004379 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
0.1 0.5 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 1.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 0.8 GO:0030911 TPR domain binding(GO:0030911)
0.1 0.4 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.1 0.5 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.1 0.5 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.1 0.3 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.1 0.5 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.1 0.3 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.1 0.2 GO:0035500 MH2 domain binding(GO:0035500)
0.1 0.5 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.1 0.5 GO:0034056 estrogen response element binding(GO:0034056)
0.1 1.0 GO:0045499 chemorepellent activity(GO:0045499)
0.1 0.4 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.2 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1 0.3 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.1 0.3 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.1 0.6 GO:0039706 co-receptor binding(GO:0039706)
0.1 0.2 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 0.3 GO:0052656 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.1 0.2 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.1 0.3 GO:0001601 peptide YY receptor activity(GO:0001601)
0.1 0.4 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.1 0.5 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.2 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.7 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.7 GO:0003680 AT DNA binding(GO:0003680)
0.0 1.1 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.5 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.2 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.2 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.0 0.5 GO:0005522 profilin binding(GO:0005522)
0.0 0.8 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.2 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.2 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.1 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.2 GO:0097001 ceramide binding(GO:0097001)
0.0 0.7 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.4 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.6 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.2 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.4 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.3 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.1 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.3 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.1 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.2 GO:0015377 cation:chloride symporter activity(GO:0015377)
0.0 0.1 GO:0001639 PLC activating G-protein coupled glutamate receptor activity(GO:0001639) G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530)
0.0 0.3 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.2 GO:0008135 translation factor activity, RNA binding(GO:0008135)
0.0 1.2 GO:0030507 spectrin binding(GO:0030507)
0.0 0.2 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 0.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.3 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.4 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.7 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 1.0 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 1.7 GO:0101005 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.1 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.0 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0 0.1 GO:0046972 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 0.4 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.3 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.2 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.1 GO:1903136 cuprous ion binding(GO:1903136)
0.0 0.4 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.4 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.3 GO:0048156 tau protein binding(GO:0048156)
0.0 0.1 GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.0 0.1 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.5 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.4 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.2 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.2 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.0 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.5 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.1 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.3 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.2 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.2 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.9 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 1.8 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 1.2 PID AURORA B PATHWAY Aurora B signaling
0.0 0.5 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.7 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.2 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.5 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.5 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.4 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 1.3 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.5 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.4 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.7 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 0.5 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.0 0.3 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.2 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.0 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.5 PID PLK1 PATHWAY PLK1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.1 0.6 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.1 2.0 REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION Genes involved in Nuclear Events (kinase and transcription factor activation)
0.0 0.7 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.5 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.1 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.7 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.5 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.6 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.4 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.5 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.2 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.2 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 0.2 REACTOME SHC MEDIATED SIGNALLING Genes involved in SHC-mediated signalling
0.0 0.3 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 0.5 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.3 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.2 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.3 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.3 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.5 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.5 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.4 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.1 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.3 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.4 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.1 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.1 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.3 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse