avrg: GSE58827: Dynamics of the Mouse Liver
Gene Symbol | Gene ID | Gene Info |
---|---|---|
T
|
ENSMUSG00000062327.4 | brachyury, T-box transcription factor T |
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
T | mm10_v2_chr17_+_8434423_8434423 | -0.48 | 3.1e-03 | Click! |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.4 | 5.4 | GO:0034653 | diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653) |
1.1 | 4.3 | GO:0000711 | meiotic DNA repair synthesis(GO:0000711) female meiosis sister chromatid cohesion(GO:0007066) |
1.0 | 7.3 | GO:0042905 | 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905) |
0.9 | 2.6 | GO:0031335 | regulation of sulfur amino acid metabolic process(GO:0031335) |
0.7 | 2.2 | GO:0015866 | ADP transport(GO:0015866) |
0.6 | 1.9 | GO:1902524 | positive regulation of protein K48-linked ubiquitination(GO:1902524) |
0.5 | 2.7 | GO:0042908 | xenobiotic transport(GO:0042908) |
0.5 | 1.5 | GO:0045013 | carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014) |
0.5 | 8.3 | GO:0052695 | cellular glucuronidation(GO:0052695) |
0.4 | 1.8 | GO:0070178 | D-serine metabolic process(GO:0070178) |
0.4 | 1.8 | GO:0006548 | histidine catabolic process(GO:0006548) |
0.4 | 3.6 | GO:0042573 | retinoic acid metabolic process(GO:0042573) |
0.3 | 2.7 | GO:0090074 | negative regulation of protein homodimerization activity(GO:0090074) |
0.3 | 1.0 | GO:1901053 | sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053) |
0.3 | 1.9 | GO:0043102 | amino acid salvage(GO:0043102) L-methionine salvage(GO:0071267) |
0.3 | 8.4 | GO:0080184 | response to phenylpropanoid(GO:0080184) |
0.3 | 0.8 | GO:0032474 | otolith morphogenesis(GO:0032474) |
0.2 | 1.7 | GO:0008078 | mesodermal cell migration(GO:0008078) |
0.2 | 1.3 | GO:0051790 | short-chain fatty acid biosynthetic process(GO:0051790) |
0.2 | 0.9 | GO:0015867 | ATP transport(GO:0015867) |
0.2 | 1.2 | GO:0042373 | vitamin K metabolic process(GO:0042373) |
0.2 | 0.7 | GO:0035519 | protein K29-linked ubiquitination(GO:0035519) |
0.2 | 1.7 | GO:0034983 | peptidyl-lysine deacetylation(GO:0034983) |
0.2 | 2.2 | GO:0035845 | photoreceptor cell outer segment organization(GO:0035845) |
0.1 | 1.3 | GO:0097501 | stress response to metal ion(GO:0097501) |
0.1 | 0.8 | GO:0006741 | NADP biosynthetic process(GO:0006741) |
0.1 | 2.0 | GO:1904262 | negative regulation of TORC1 signaling(GO:1904262) |
0.1 | 2.1 | GO:0048672 | positive regulation of collateral sprouting(GO:0048672) |
0.1 | 1.6 | GO:0006857 | oligopeptide transport(GO:0006857) |
0.1 | 2.1 | GO:0042178 | xenobiotic catabolic process(GO:0042178) |
0.1 | 0.5 | GO:0006421 | asparaginyl-tRNA aminoacylation(GO:0006421) |
0.1 | 0.6 | GO:0060011 | Sertoli cell proliferation(GO:0060011) |
0.1 | 1.7 | GO:0090161 | Golgi ribbon formation(GO:0090161) |
0.1 | 0.3 | GO:0060796 | regulation of transcription involved in primary germ layer cell fate commitment(GO:0060796) |
0.1 | 0.4 | GO:0045716 | positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716) |
0.1 | 0.6 | GO:0000395 | mRNA 5'-splice site recognition(GO:0000395) |
0.1 | 0.8 | GO:0001574 | ganglioside biosynthetic process(GO:0001574) |
0.1 | 0.5 | GO:0015871 | choline transport(GO:0015871) |
0.1 | 0.6 | GO:0070314 | G1 to G0 transition(GO:0070314) |
0.1 | 0.5 | GO:0033227 | dsRNA transport(GO:0033227) |
0.1 | 0.6 | GO:2000189 | positive regulation of cholesterol homeostasis(GO:2000189) |
0.1 | 0.9 | GO:0046415 | urate metabolic process(GO:0046415) |
0.1 | 1.1 | GO:0021520 | spinal cord motor neuron cell fate specification(GO:0021520) |
0.0 | 1.0 | GO:0060575 | intestinal epithelial cell differentiation(GO:0060575) |
0.0 | 0.2 | GO:0003349 | epicardium-derived cardiac endothelial cell differentiation(GO:0003349) |
0.0 | 0.2 | GO:0070318 | positive regulation of G0 to G1 transition(GO:0070318) |
0.0 | 0.6 | GO:0035814 | negative regulation of renal sodium excretion(GO:0035814) |
0.0 | 0.4 | GO:0021902 | commitment of neuronal cell to specific neuron type in forebrain(GO:0021902) |
0.0 | 0.4 | GO:2000318 | positive regulation of T-helper 17 type immune response(GO:2000318) |
0.0 | 0.1 | GO:0098974 | postsynaptic actin cytoskeleton organization(GO:0098974) |
0.0 | 0.2 | GO:0002457 | T cell antigen processing and presentation(GO:0002457) |
0.0 | 0.6 | GO:0060272 | embryonic skeletal joint morphogenesis(GO:0060272) |
0.0 | 0.5 | GO:0036159 | inner dynein arm assembly(GO:0036159) |
0.0 | 0.6 | GO:0071786 | endoplasmic reticulum tubular network organization(GO:0071786) |
0.0 | 0.1 | GO:0043461 | proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272) |
0.0 | 0.3 | GO:0071763 | nuclear membrane organization(GO:0071763) |
0.0 | 0.8 | GO:0071218 | cellular response to misfolded protein(GO:0071218) |
0.0 | 0.4 | GO:0007128 | meiotic prophase I(GO:0007128) prophase(GO:0051324) |
0.0 | 1.9 | GO:0019369 | arachidonic acid metabolic process(GO:0019369) |
0.0 | 0.3 | GO:0009162 | deoxyribonucleoside monophosphate metabolic process(GO:0009162) |
0.0 | 0.4 | GO:0060391 | positive regulation of SMAD protein import into nucleus(GO:0060391) |
0.0 | 0.5 | GO:0033539 | fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539) |
0.0 | 0.9 | GO:0042036 | negative regulation of cytokine biosynthetic process(GO:0042036) |
0.0 | 0.1 | GO:0015676 | vanadium ion transport(GO:0015676) lead ion transport(GO:0015692) |
0.0 | 0.9 | GO:0060765 | regulation of androgen receptor signaling pathway(GO:0060765) |
0.0 | 0.2 | GO:0048633 | positive regulation of skeletal muscle tissue growth(GO:0048633) |
0.0 | 0.2 | GO:2000645 | negative regulation of receptor catabolic process(GO:2000645) |
0.0 | 0.7 | GO:0015985 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
0.0 | 1.0 | GO:0019432 | triglyceride biosynthetic process(GO:0019432) |
0.0 | 0.3 | GO:0048934 | peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935) |
0.0 | 0.2 | GO:0007343 | egg activation(GO:0007343) |
0.0 | 0.1 | GO:0071725 | response to diacyl bacterial lipopeptide(GO:0071724) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to diacyl bacterial lipopeptide(GO:0071726) cellular response to triacyl bacterial lipopeptide(GO:0071727) |
0.0 | 0.8 | GO:0061003 | positive regulation of dendritic spine morphogenesis(GO:0061003) |
0.0 | 0.5 | GO:0043252 | sodium-independent organic anion transport(GO:0043252) |
0.0 | 0.8 | GO:0070232 | regulation of T cell apoptotic process(GO:0070232) |
0.0 | 0.2 | GO:0043402 | glucocorticoid mediated signaling pathway(GO:0043402) |
0.0 | 0.2 | GO:0001672 | regulation of chromatin assembly or disassembly(GO:0001672) |
0.0 | 1.7 | GO:0060349 | bone morphogenesis(GO:0060349) |
0.0 | 0.2 | GO:0051205 | protein insertion into membrane(GO:0051205) |
0.0 | 0.5 | GO:1902108 | regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902108) |
0.0 | 0.1 | GO:0006348 | chromatin silencing at telomere(GO:0006348) |
0.0 | 0.1 | GO:0015074 | DNA integration(GO:0015074) |
0.0 | 0.0 | GO:0035627 | ceramide transport(GO:0035627) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.1 | 4.3 | GO:0000802 | transverse filament(GO:0000802) |
0.3 | 1.2 | GO:1902636 | kinociliary basal body(GO:1902636) |
0.1 | 0.5 | GO:0045251 | mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251) |
0.1 | 1.1 | GO:0019907 | cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907) |
0.1 | 1.4 | GO:0031209 | SCAR complex(GO:0031209) |
0.1 | 0.6 | GO:0031983 | vesicle lumen(GO:0031983) |
0.1 | 1.0 | GO:0036038 | MKS complex(GO:0036038) |
0.1 | 0.6 | GO:0097136 | Bcl-2 family protein complex(GO:0097136) |
0.1 | 1.7 | GO:0070971 | endoplasmic reticulum exit site(GO:0070971) |
0.1 | 0.7 | GO:0000276 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) |
0.0 | 0.5 | GO:0036156 | inner dynein arm(GO:0036156) |
0.0 | 0.9 | GO:0005779 | integral component of peroxisomal membrane(GO:0005779) |
0.0 | 0.1 | GO:0070826 | paraferritin complex(GO:0070826) |
0.0 | 0.5 | GO:0033391 | chromatoid body(GO:0033391) |
0.0 | 0.6 | GO:0071782 | endoplasmic reticulum tubular network(GO:0071782) |
0.0 | 3.0 | GO:0072562 | blood microparticle(GO:0072562) |
0.0 | 1.3 | GO:0099501 | synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501) |
0.0 | 0.4 | GO:0005685 | U1 snRNP(GO:0005685) |
0.0 | 0.6 | GO:0035145 | exon-exon junction complex(GO:0035145) |
0.0 | 0.4 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
0.0 | 0.6 | GO:0055038 | recycling endosome membrane(GO:0055038) |
0.0 | 6.3 | GO:0005743 | mitochondrial inner membrane(GO:0005743) |
0.0 | 0.8 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
0.0 | 0.1 | GO:0046696 | lipopolysaccharide receptor complex(GO:0046696) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
3.6 | 10.9 | GO:0018479 | benzaldehyde dehydrogenase (NAD+) activity(GO:0018479) |
1.8 | 5.4 | GO:0008401 | retinoic acid 4-hydroxylase activity(GO:0008401) |
1.0 | 3.1 | GO:0015228 | coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122) |
0.9 | 2.6 | GO:0016206 | catechol O-methyltransferase activity(GO:0016206) |
0.6 | 1.8 | GO:0016855 | racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661) |
0.4 | 2.7 | GO:0008559 | xenobiotic-transporting ATPase activity(GO:0008559) |
0.3 | 1.0 | GO:0008480 | sarcosine dehydrogenase activity(GO:0008480) |
0.3 | 1.3 | GO:0004315 | 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315) |
0.3 | 12.3 | GO:0015020 | glucuronosyltransferase activity(GO:0015020) |
0.3 | 1.2 | GO:0004090 | carbonyl reductase (NADPH) activity(GO:0004090) |
0.2 | 1.6 | GO:0015198 | oligopeptide transporter activity(GO:0015198) |
0.2 | 2.3 | GO:0001594 | trace-amine receptor activity(GO:0001594) |
0.2 | 6.6 | GO:1900750 | glutathione binding(GO:0043295) oligopeptide binding(GO:1900750) |
0.2 | 1.0 | GO:0008195 | phosphatidate phosphatase activity(GO:0008195) |
0.2 | 2.7 | GO:0048273 | mitogen-activated protein kinase p38 binding(GO:0048273) |
0.2 | 1.0 | GO:0008172 | S-methyltransferase activity(GO:0008172) |
0.2 | 0.5 | GO:0004816 | asparagine-tRNA ligase activity(GO:0004816) |
0.1 | 1.2 | GO:0002046 | opsin binding(GO:0002046) |
0.1 | 1.7 | GO:0070403 | NAD+ binding(GO:0070403) |
0.1 | 2.7 | GO:0004364 | glutathione transferase activity(GO:0004364) |
0.1 | 0.6 | GO:0044547 | DNA topoisomerase binding(GO:0044547) |
0.1 | 0.8 | GO:0001665 | alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665) |
0.1 | 0.5 | GO:0051033 | nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033) |
0.1 | 0.4 | GO:0035614 | snRNA stem-loop binding(GO:0035614) |
0.1 | 0.5 | GO:0015220 | choline transmembrane transporter activity(GO:0015220) |
0.1 | 2.0 | GO:0070330 | aromatase activity(GO:0070330) |
0.1 | 0.9 | GO:1901702 | urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702) |
0.1 | 0.2 | GO:0036033 | mediator complex binding(GO:0036033) |
0.1 | 0.2 | GO:0004711 | ribosomal protein S6 kinase activity(GO:0004711) |
0.1 | 0.7 | GO:0045236 | CXCR chemokine receptor binding(GO:0045236) |
0.1 | 0.5 | GO:0015217 | ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217) |
0.1 | 0.6 | GO:0030306 | ADP-ribosylation factor binding(GO:0030306) |
0.0 | 0.2 | GO:0031849 | olfactory receptor binding(GO:0031849) |
0.0 | 1.0 | GO:0051787 | misfolded protein binding(GO:0051787) |
0.0 | 0.1 | GO:0098918 | structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973) |
0.0 | 1.3 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
0.0 | 0.8 | GO:0003951 | NAD+ kinase activity(GO:0003951) |
0.0 | 0.9 | GO:0016702 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702) |
0.0 | 0.6 | GO:0051400 | BH domain binding(GO:0051400) |
0.0 | 1.8 | GO:0016836 | hydro-lyase activity(GO:0016836) |
0.0 | 0.2 | GO:0032453 | histone demethylase activity (H3-K4 specific)(GO:0032453) |
0.0 | 0.2 | GO:0043423 | 3-phosphoinositide-dependent protein kinase binding(GO:0043423) |
0.0 | 0.1 | GO:0015639 | cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639) |
0.0 | 0.6 | GO:0070006 | metalloaminopeptidase activity(GO:0070006) |
0.0 | 0.2 | GO:0052629 | phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629) |
0.0 | 1.5 | GO:0001205 | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205) |
0.0 | 0.9 | GO:0050681 | androgen receptor binding(GO:0050681) |
0.0 | 0.5 | GO:0015347 | sodium-independent organic anion transmembrane transporter activity(GO:0015347) |
0.0 | 0.4 | GO:0004679 | AMP-activated protein kinase activity(GO:0004679) |
0.0 | 0.5 | GO:0008569 | ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569) |
0.0 | 1.4 | GO:0048365 | Rac GTPase binding(GO:0048365) |
0.0 | 0.8 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
0.0 | 1.0 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
0.0 | 1.0 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
0.0 | 0.2 | GO:0004128 | cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128) |
0.0 | 0.0 | GO:0034191 | apolipoprotein A-I receptor binding(GO:0034191) |
0.0 | 3.5 | GO:0061630 | ubiquitin protein ligase activity(GO:0061630) |
0.0 | 0.2 | GO:0017160 | Ral GTPase binding(GO:0017160) |
0.0 | 0.3 | GO:0005521 | lamin binding(GO:0005521) |
0.0 | 0.2 | GO:0004435 | phosphatidylinositol phospholipase C activity(GO:0004435) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 4.4 | ST PHOSPHOINOSITIDE 3 KINASE PATHWAY | PI3K Pathway |
0.1 | 2.3 | PID LIS1 PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
0.1 | 1.7 | PID HDAC CLASSIII PATHWAY | Signaling events mediated by HDAC Class III |
0.0 | 2.7 | PID ARF6 TRAFFICKING PATHWAY | Arf6 trafficking events |
0.0 | 2.2 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
0.0 | 1.4 | PID ECADHERIN NASCENT AJ PATHWAY | E-cadherin signaling in the nascent adherens junction |
0.0 | 0.4 | PID FRA PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
0.0 | 1.8 | PID NFAT TFPATHWAY | Calcineurin-regulated NFAT-dependent transcription in lymphocytes |
0.0 | 2.0 | PID CMYB PATHWAY | C-MYB transcription factor network |
0.0 | 0.8 | PID ERBB1 INTERNALIZATION PATHWAY | Internalization of ErbB1 |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.2 | 7.3 | REACTOME ETHANOL OXIDATION | Genes involved in Ethanol oxidation |
0.3 | 2.7 | REACTOME RECYCLING OF BILE ACIDS AND SALTS | Genes involved in Recycling of bile acids and salts |
0.2 | 5.4 | REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE | Genes involved in Cytochrome P450 - arranged by substrate type |
0.2 | 1.6 | REACTOME TRANSPORT OF ORGANIC ANIONS | Genes involved in Transport of organic anions |
0.2 | 6.6 | REACTOME GLUTATHIONE CONJUGATION | Genes involved in Glutathione conjugation |
0.1 | 2.6 | REACTOME PHASE II CONJUGATION | Genes involved in Phase II conjugation |
0.1 | 0.9 | REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS | Genes involved in Facilitative Na+-independent glucose transporters |
0.1 | 4.3 | REACTOME MEIOTIC SYNAPSIS | Genes involved in Meiotic Synapsis |
0.1 | 1.0 | REACTOME METABOLISM OF POLYAMINES | Genes involved in Metabolism of polyamines |
0.1 | 1.0 | REACTOME SYNTHESIS OF PE | Genes involved in Synthesis of PE |
0.1 | 1.3 | REACTOME ZINC TRANSPORTERS | Genes involved in Zinc transporters |
0.0 | 1.5 | REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS | Genes involved in Regulation of gene expression in beta cells |
0.0 | 0.7 | REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING | Genes involved in Formation of ATP by chemiosmotic coupling |
0.0 | 0.5 | REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK | Genes involved in Regulation of Rheb GTPase activity by AMPK |
0.0 | 0.5 | REACTOME SYNTHESIS OF PC | Genes involved in Synthesis of PC |
0.0 | 0.9 | REACTOME PEROXISOMAL LIPID METABOLISM | Genes involved in Peroxisomal lipid metabolism |
0.0 | 2.3 | REACTOME L1CAM INTERACTIONS | Genes involved in L1CAM interactions |
0.0 | 0.6 | REACTOME MRNA 3 END PROCESSING | Genes involved in mRNA 3'-end processing |
0.0 | 0.2 | REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE | Genes involved in Synthesis of PIPs at the late endosome membrane |
0.0 | 0.2 | REACTOME MTORC1 MEDIATED SIGNALLING | Genes involved in mTORC1-mediated signalling |