avrg: GSE58827: Dynamics of the Mouse Liver
Gene Symbol | Gene ID | Gene Info |
---|---|---|
Rora
|
ENSMUSG00000032238.11 | RAR-related orphan receptor alpha |
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Rora | mm10_v2_chr9_+_68653761_68653786 | 0.10 | 5.6e-01 | Click! |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.6 | 1.8 | GO:0002182 | cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248) |
0.5 | 1.4 | GO:0035585 | calcium-mediated signaling using extracellular calcium source(GO:0035585) |
0.4 | 1.1 | GO:1904158 | axonemal central apparatus assembly(GO:1904158) |
0.3 | 1.0 | GO:2000417 | negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of integrin activation(GO:0033624) negative regulation of interleukin-1 alpha secretion(GO:0050712) regulation of matrix metallopeptidase secretion(GO:1904464) matrix metallopeptidase secretion(GO:1990773) positive regulation of ovarian follicle development(GO:2000386) regulation of antral ovarian follicle growth(GO:2000387) positive regulation of antral ovarian follicle growth(GO:2000388) negative regulation of eosinophil migration(GO:2000417) |
0.3 | 2.0 | GO:0007144 | female meiosis I(GO:0007144) |
0.2 | 1.4 | GO:0010747 | positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747) |
0.2 | 1.4 | GO:0044806 | G-quadruplex DNA unwinding(GO:0044806) |
0.2 | 0.8 | GO:1903288 | positive regulation of potassium ion import(GO:1903288) |
0.2 | 0.7 | GO:2000158 | positive regulation of ubiquitin-specific protease activity(GO:2000158) |
0.2 | 1.0 | GO:0045585 | regulation of cytotoxic T cell differentiation(GO:0045583) positive regulation of cytotoxic T cell differentiation(GO:0045585) |
0.1 | 0.6 | GO:0033140 | negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140) |
0.1 | 0.6 | GO:0036376 | sodium ion export from cell(GO:0036376) |
0.1 | 0.3 | GO:0071929 | alpha-tubulin acetylation(GO:0071929) |
0.1 | 1.1 | GO:2000741 | positive regulation of mesenchymal stem cell differentiation(GO:2000741) |
0.1 | 0.9 | GO:0018344 | protein geranylgeranylation(GO:0018344) |
0.1 | 0.3 | GO:2000642 | intralumenal vesicle formation(GO:0070676) negative regulation of early endosome to late endosome transport(GO:2000642) |
0.1 | 1.1 | GO:0030432 | peristalsis(GO:0030432) |
0.1 | 0.9 | GO:2000348 | regulation of CD40 signaling pathway(GO:2000348) |
0.1 | 1.7 | GO:2000251 | positive regulation of actin cytoskeleton reorganization(GO:2000251) |
0.1 | 0.4 | GO:0048014 | negative regulation of cytokine secretion involved in immune response(GO:0002740) Tie signaling pathway(GO:0048014) |
0.1 | 0.2 | GO:1903969 | negative regulation of interleukin-6-mediated signaling pathway(GO:0070104) regulation of macrophage colony-stimulating factor signaling pathway(GO:1902226) regulation of response to macrophage colony-stimulating factor(GO:1903969) regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903972) |
0.1 | 0.2 | GO:0060399 | positive regulation of growth hormone receptor signaling pathway(GO:0060399) |
0.1 | 0.2 | GO:0019858 | cytosine metabolic process(GO:0019858) |
0.1 | 0.2 | GO:0048686 | regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690) |
0.1 | 0.3 | GO:0007113 | endomitotic cell cycle(GO:0007113) |
0.1 | 0.2 | GO:0071846 | actin filament debranching(GO:0071846) |
0.1 | 0.6 | GO:0033353 | S-adenosylmethionine cycle(GO:0033353) |
0.1 | 0.5 | GO:0006369 | termination of RNA polymerase II transcription(GO:0006369) |
0.1 | 0.2 | GO:0090158 | endoplasmic reticulum membrane organization(GO:0090158) |
0.1 | 0.3 | GO:0000160 | phosphorelay signal transduction system(GO:0000160) |
0.1 | 0.3 | GO:0021888 | cerebral cortex tangential migration using cell-axon interactions(GO:0021824) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888) facioacoustic ganglion development(GO:1903375) |
0.1 | 0.4 | GO:0010616 | negative regulation of cardiac muscle adaptation(GO:0010616) |
0.0 | 0.2 | GO:0048808 | male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598) |
0.0 | 0.3 | GO:0032929 | negative regulation of superoxide anion generation(GO:0032929) |
0.0 | 0.4 | GO:0030718 | germ-line stem cell population maintenance(GO:0030718) |
0.0 | 0.2 | GO:0045218 | zonula adherens maintenance(GO:0045218) |
0.0 | 0.1 | GO:0045872 | regulation of rhodopsin gene expression(GO:0007468) positive regulation of rhodopsin gene expression(GO:0045872) |
0.0 | 0.5 | GO:1904659 | glucose transmembrane transport(GO:1904659) |
0.0 | 0.6 | GO:0090141 | positive regulation of mitochondrial fission(GO:0090141) |
0.0 | 0.4 | GO:0045945 | positive regulation of transcription from RNA polymerase III promoter(GO:0045945) |
0.0 | 0.3 | GO:0043313 | regulation of neutrophil degranulation(GO:0043313) regulation of neutrophil activation(GO:1902563) |
0.0 | 0.9 | GO:0008340 | determination of adult lifespan(GO:0008340) |
0.0 | 0.4 | GO:0090136 | epithelial cell-cell adhesion(GO:0090136) |
0.0 | 0.1 | GO:0051562 | negative regulation of mitochondrial calcium ion concentration(GO:0051562) |
0.0 | 0.2 | GO:1990034 | calcium ion export from cell(GO:1990034) |
0.0 | 0.6 | GO:0032211 | negative regulation of telomere maintenance via telomerase(GO:0032211) |
0.0 | 0.5 | GO:1903818 | positive regulation of voltage-gated potassium channel activity(GO:1903818) |
0.0 | 0.3 | GO:0019800 | peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800) |
0.0 | 0.2 | GO:0051683 | establishment of Golgi localization(GO:0051683) |
0.0 | 0.1 | GO:0003199 | endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199) |
0.0 | 0.1 | GO:0015960 | basophil activation involved in immune response(GO:0002276) diadenosine polyphosphate biosynthetic process(GO:0015960) diadenosine tetraphosphate metabolic process(GO:0015965) diadenosine tetraphosphate biosynthetic process(GO:0015966) |
0.0 | 0.3 | GO:0018206 | peptidyl-methionine modification(GO:0018206) |
0.0 | 0.1 | GO:2000210 | positive regulation of anoikis(GO:2000210) |
0.0 | 0.6 | GO:0001539 | cilium or flagellum-dependent cell motility(GO:0001539) cilium-dependent cell motility(GO:0060285) |
0.0 | 0.1 | GO:0090403 | oxidative stress-induced premature senescence(GO:0090403) |
0.0 | 0.1 | GO:1901994 | negative regulation of meiotic cell cycle phase transition(GO:1901994) |
0.0 | 0.4 | GO:0007096 | regulation of exit from mitosis(GO:0007096) |
0.0 | 0.1 | GO:0046103 | inosine biosynthetic process(GO:0046103) |
0.0 | 0.4 | GO:0048172 | regulation of short-term neuronal synaptic plasticity(GO:0048172) |
0.0 | 0.1 | GO:0003137 | Notch signaling pathway involved in heart induction(GO:0003137) regulation of Notch signaling pathway involved in heart induction(GO:0035480) positive regulation of Notch signaling pathway involved in heart induction(GO:0035481) arterial endothelial cell fate commitment(GO:0060844) blood vessel endothelial cell fate commitment(GO:0060846) Notch signaling pathway involved in arterial endothelial cell fate commitment(GO:0060853) blood vessel lumenization(GO:0072554) blood vessel endothelial cell fate specification(GO:0097101) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066) |
0.0 | 0.4 | GO:0006972 | hyperosmotic response(GO:0006972) |
0.0 | 0.8 | GO:0090162 | establishment of epithelial cell polarity(GO:0090162) |
0.0 | 0.4 | GO:0032012 | ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012) |
0.0 | 0.2 | GO:0070601 | centromeric sister chromatid cohesion(GO:0070601) |
0.0 | 0.4 | GO:0032693 | positive regulation of T-helper 1 type immune response(GO:0002827) negative regulation of interleukin-10 production(GO:0032693) |
0.0 | 0.1 | GO:0036444 | calcium ion transmembrane import into mitochondrion(GO:0036444) |
0.0 | 0.2 | GO:0031077 | post-embryonic camera-type eye development(GO:0031077) |
0.0 | 0.4 | GO:0048026 | positive regulation of mRNA splicing, via spliceosome(GO:0048026) |
0.0 | 0.3 | GO:0050872 | white fat cell differentiation(GO:0050872) |
0.0 | 0.3 | GO:0034587 | piRNA metabolic process(GO:0034587) |
0.0 | 1.0 | GO:0071277 | cellular response to calcium ion(GO:0071277) |
0.0 | 0.1 | GO:0060267 | positive regulation of respiratory burst(GO:0060267) |
0.0 | 0.1 | GO:0090074 | negative regulation of protein homodimerization activity(GO:0090074) |
0.0 | 0.1 | GO:0090400 | stress-induced premature senescence(GO:0090400) |
0.0 | 0.3 | GO:0016578 | histone deubiquitination(GO:0016578) |
0.0 | 0.7 | GO:0006414 | translational elongation(GO:0006414) |
0.0 | 0.3 | GO:1902043 | positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043) |
0.0 | 0.2 | GO:0033523 | histone H2B ubiquitination(GO:0033523) |
0.0 | 0.1 | GO:0048733 | sebaceous gland development(GO:0048733) |
0.0 | 0.1 | GO:0014886 | transition between slow and fast fiber(GO:0014886) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 1.4 | GO:0031095 | platelet dense tubular network membrane(GO:0031095) |
0.2 | 1.2 | GO:0005927 | muscle tendon junction(GO:0005927) |
0.2 | 0.9 | GO:0005968 | Rab-protein geranylgeranyltransferase complex(GO:0005968) |
0.1 | 1.3 | GO:0005890 | sodium:potassium-exchanging ATPase complex(GO:0005890) |
0.1 | 1.7 | GO:0071439 | clathrin complex(GO:0071439) |
0.1 | 0.7 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
0.1 | 0.5 | GO:0097226 | sperm mitochondrial sheath(GO:0097226) |
0.1 | 1.3 | GO:0097512 | cardiac myofibril(GO:0097512) |
0.1 | 1.8 | GO:0030014 | CCR4-NOT complex(GO:0030014) |
0.1 | 0.2 | GO:0072534 | perineuronal net(GO:0072534) |
0.1 | 0.6 | GO:0000782 | telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783) |
0.0 | 0.1 | GO:0031074 | nucleocytoplasmic shuttling complex(GO:0031074) |
0.0 | 0.2 | GO:0005784 | Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256) |
0.0 | 0.3 | GO:0097427 | microtubule bundle(GO:0097427) |
0.0 | 0.3 | GO:0071546 | pi-body(GO:0071546) |
0.0 | 0.3 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
0.0 | 0.2 | GO:0097413 | Lewy body(GO:0097413) |
0.0 | 0.1 | GO:0005745 | m-AAA complex(GO:0005745) |
0.0 | 0.3 | GO:0032009 | early phagosome(GO:0032009) |
0.0 | 0.2 | GO:0005915 | zonula adherens(GO:0005915) |
0.0 | 0.3 | GO:0005916 | fascia adherens(GO:0005916) |
0.0 | 0.2 | GO:0016593 | Cdc73/Paf1 complex(GO:0016593) |
0.0 | 0.2 | GO:0031415 | NatA complex(GO:0031415) |
0.0 | 0.2 | GO:0030126 | COPI vesicle coat(GO:0030126) |
0.0 | 1.4 | GO:0005657 | replication fork(GO:0005657) |
0.0 | 0.5 | GO:0005849 | mRNA cleavage factor complex(GO:0005849) |
0.0 | 1.8 | GO:0000922 | spindle pole(GO:0000922) |
0.0 | 0.4 | GO:0035145 | exon-exon junction complex(GO:0035145) |
0.0 | 0.1 | GO:0002193 | MAML1-RBP-Jkappa- ICN1 complex(GO:0002193) |
0.0 | 0.1 | GO:0001520 | outer dense fiber(GO:0001520) |
0.0 | 0.4 | GO:0044665 | MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339) |
0.0 | 0.2 | GO:0010369 | chromocenter(GO:0010369) |
0.0 | 0.1 | GO:0033180 | proton-transporting V-type ATPase, V1 domain(GO:0033180) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 1.4 | GO:0033680 | ATP-dependent DNA/RNA helicase activity(GO:0033680) |
0.2 | 1.1 | GO:0004994 | somatostatin receptor activity(GO:0004994) |
0.2 | 0.7 | GO:0035800 | deubiquitinase activator activity(GO:0035800) |
0.2 | 1.0 | GO:0002135 | CTP binding(GO:0002135) |
0.1 | 1.0 | GO:0004957 | prostaglandin E receptor activity(GO:0004957) |
0.1 | 0.8 | GO:0042731 | PH domain binding(GO:0042731) |
0.1 | 1.3 | GO:0005391 | sodium:potassium-exchanging ATPase activity(GO:0005391) |
0.1 | 0.4 | GO:0030144 | alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144) |
0.1 | 0.3 | GO:0004967 | glucagon receptor activity(GO:0004967) |
0.1 | 1.8 | GO:0102391 | decanoate--CoA ligase activity(GO:0102391) |
0.1 | 0.4 | GO:0005143 | interleukin-12 receptor binding(GO:0005143) |
0.1 | 1.1 | GO:0035925 | mRNA 3'-UTR AU-rich region binding(GO:0035925) |
0.1 | 0.2 | GO:0097677 | STAT family protein binding(GO:0097677) |
0.1 | 0.7 | GO:0034711 | inhibin binding(GO:0034711) |
0.1 | 0.6 | GO:0004013 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
0.1 | 0.4 | GO:0004563 | beta-N-acetylhexosaminidase activity(GO:0004563) |
0.1 | 0.3 | GO:0000155 | phosphorelay sensor kinase activity(GO:0000155) |
0.0 | 0.2 | GO:1990269 | RNA polymerase II C-terminal domain phosphoserine binding(GO:1990269) |
0.0 | 0.3 | GO:0004468 | lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468) |
0.0 | 0.4 | GO:0043023 | ribosomal large subunit binding(GO:0043023) |
0.0 | 0.5 | GO:0005412 | glucose:sodium symporter activity(GO:0005412) |
0.0 | 0.2 | GO:0070579 | methylcytosine dioxygenase activity(GO:0070579) |
0.0 | 0.9 | GO:0070182 | DNA polymerase binding(GO:0070182) |
0.0 | 0.9 | GO:0005092 | GDP-dissociation inhibitor activity(GO:0005092) |
0.0 | 0.6 | GO:0016493 | C-C chemokine receptor activity(GO:0016493) |
0.0 | 1.0 | GO:0004602 | glutathione peroxidase activity(GO:0004602) |
0.0 | 0.3 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
0.0 | 0.7 | GO:0003746 | translation elongation factor activity(GO:0003746) |
0.0 | 0.4 | GO:0016004 | phospholipase activator activity(GO:0016004) |
0.0 | 0.4 | GO:0045294 | dystroglycan binding(GO:0002162) alpha-catenin binding(GO:0045294) |
0.0 | 0.4 | GO:0005172 | vascular endothelial growth factor receptor binding(GO:0005172) |
0.0 | 0.3 | GO:0003993 | acid phosphatase activity(GO:0003993) |
0.0 | 0.2 | GO:0004865 | protein serine/threonine phosphatase inhibitor activity(GO:0004865) |
0.0 | 0.2 | GO:0070097 | delta-catenin binding(GO:0070097) |
0.0 | 0.3 | GO:0008641 | small protein activating enzyme activity(GO:0008641) |
0.0 | 2.5 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
0.0 | 0.1 | GO:0016316 | phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) |
0.0 | 0.4 | GO:0032454 | histone demethylase activity (H3-K9 specific)(GO:0032454) |
0.0 | 0.4 | GO:0070016 | armadillo repeat domain binding(GO:0070016) |
0.0 | 0.1 | GO:0004449 | isocitrate dehydrogenase (NAD+) activity(GO:0004449) |
0.0 | 0.4 | GO:0070006 | metalloaminopeptidase activity(GO:0070006) |
0.0 | 0.6 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
0.0 | 0.6 | GO:0042162 | telomeric DNA binding(GO:0042162) |
0.0 | 0.1 | GO:0017040 | ceramidase activity(GO:0017040) |
0.0 | 0.3 | GO:0038191 | neuropilin binding(GO:0038191) |
0.0 | 1.4 | GO:0043621 | protein self-association(GO:0043621) |
0.0 | 0.2 | GO:0071933 | Arp2/3 complex binding(GO:0071933) |
0.0 | 0.2 | GO:0016918 | retinal binding(GO:0016918) |
0.0 | 0.2 | GO:1990825 | sequence-specific mRNA binding(GO:1990825) |
0.0 | 0.5 | GO:0000993 | RNA polymerase II core binding(GO:0000993) |
0.0 | 0.1 | GO:0004111 | creatine kinase activity(GO:0004111) |
0.0 | 0.2 | GO:0005432 | calcium:sodium antiporter activity(GO:0005432) |
0.0 | 0.1 | GO:0031812 | G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812) |
0.0 | 0.6 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
0.0 | 1.8 | GO:0004725 | protein tyrosine phosphatase activity(GO:0004725) |
0.0 | 0.2 | GO:0046625 | sphingolipid binding(GO:0046625) |
0.0 | 2.0 | GO:0004984 | olfactory receptor activity(GO:0004984) |
0.0 | 0.4 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
0.0 | 1.1 | GO:0051082 | unfolded protein binding(GO:0051082) |
0.0 | 0.1 | GO:0043522 | leucine zipper domain binding(GO:0043522) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 1.9 | SA G2 AND M PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
0.1 | 2.3 | PID INTEGRIN A9B1 PATHWAY | Alpha9 beta1 integrin signaling events |
0.1 | 1.0 | PID ERBB NETWORK PATHWAY | ErbB receptor signaling network |
0.0 | 0.9 | PID BARD1 PATHWAY | BARD1 signaling events |
0.0 | 1.0 | PID RAS PATHWAY | Regulation of Ras family activation |
0.0 | 0.4 | SA PTEN PATHWAY | PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate. |
0.0 | 1.3 | PID TELOMERASE PATHWAY | Regulation of Telomerase |
0.0 | 0.3 | PID INSULIN GLUCOSE PATHWAY | Insulin-mediated glucose transport |
0.0 | 0.8 | PID E2F PATHWAY | E2F transcription factor network |
0.0 | 0.6 | PID ECADHERIN STABILIZATION PATHWAY | Stabilization and expansion of the E-cadherin adherens junction |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 0.4 | REACTOME ENDOSOMAL VACUOLAR PATHWAY | Genes involved in Endosomal/Vacuolar pathway |
0.1 | 1.9 | REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION | Genes involved in Cyclin A/B1 associated events during G2/M transition |
0.1 | 1.0 | REACTOME PROSTANOID LIGAND RECEPTORS | Genes involved in Prostanoid ligand receptors |
0.1 | 0.9 | REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY | Genes involved in Regulation of the Fanconi anemia pathway |
0.1 | 1.2 | REACTOME SEMA3A PAK DEPENDENT AXON REPULSION | Genes involved in Sema3A PAK dependent Axon repulsion |
0.1 | 0.9 | REACTOME HYALURONAN METABOLISM | Genes involved in Hyaluronan metabolism |
0.0 | 1.4 | REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS | Genes involved in Synthesis of very long-chain fatty acyl-CoAs |
0.0 | 0.7 | REACTOME TRAF6 MEDIATED IRF7 ACTIVATION | Genes involved in TRAF6 mediated IRF7 activation |
0.0 | 0.5 | REACTOME PROCESSING OF INTRONLESS PRE MRNAS | Genes involved in Processing of Intronless Pre-mRNAs |
0.0 | 1.3 | REACTOME ION TRANSPORT BY P TYPE ATPASES | Genes involved in Ion transport by P-type ATPases |
0.0 | 0.2 | REACTOME PLATELET CALCIUM HOMEOSTASIS | Genes involved in Platelet calcium homeostasis |
0.0 | 1.0 | REACTOME EFFECTS OF PIP2 HYDROLYSIS | Genes involved in Effects of PIP2 hydrolysis |
0.0 | 1.0 | REACTOME GLUTATHIONE CONJUGATION | Genes involved in Glutathione conjugation |
0.0 | 0.4 | REACTOME N GLYCAN ANTENNAE ELONGATION | Genes involved in N-Glycan antennae elongation |
0.0 | 0.4 | REACTOME TIE2 SIGNALING | Genes involved in Tie2 Signaling |
0.0 | 2.4 | REACTOME SIGNALING BY EGFR IN CANCER | Genes involved in Signaling by EGFR in Cancer |
0.0 | 0.2 | REACTOME DCC MEDIATED ATTRACTIVE SIGNALING | Genes involved in DCC mediated attractive signaling |