avrg: GSE58827: Dynamics of the Mouse Liver
Gene Symbol | Gene ID | Gene Info |
---|---|---|
Hsf1
|
ENSMUSG00000022556.9 | heat shock factor 1 |
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Hsf1 | mm10_v2_chr15_+_76477404_76477461 | 0.03 | 8.5e-01 | Click! |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.7 | 4.1 | GO:0045583 | regulation of cytotoxic T cell differentiation(GO:0045583) positive regulation of cytotoxic T cell differentiation(GO:0045585) |
0.5 | 3.2 | GO:1903750 | regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751) |
0.3 | 0.8 | GO:0071492 | cellular response to UV-A(GO:0071492) |
0.2 | 1.0 | GO:0055071 | cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) manganese ion homeostasis(GO:0055071) |
0.2 | 0.9 | GO:0060715 | syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715) |
0.2 | 0.9 | GO:0035063 | nuclear speck organization(GO:0035063) |
0.1 | 1.2 | GO:0042769 | DNA damage response, detection of DNA damage(GO:0042769) |
0.1 | 0.7 | GO:0006564 | L-serine biosynthetic process(GO:0006564) |
0.1 | 0.5 | GO:1903121 | regulation of TRAIL-activated apoptotic signaling pathway(GO:1903121) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984) |
0.1 | 1.2 | GO:0099640 | positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway(GO:0038033) axo-dendritic protein transport(GO:0099640) |
0.1 | 0.5 | GO:0036233 | glycine import(GO:0036233) |
0.1 | 0.8 | GO:0044806 | G-quadruplex DNA unwinding(GO:0044806) |
0.1 | 0.4 | GO:1902268 | negative regulation of polyamine transmembrane transport(GO:1902268) |
0.1 | 0.3 | GO:0045041 | positive regulation of T cell mediated immune response to tumor cell(GO:0002842) protein import into mitochondrial intermembrane space(GO:0045041) |
0.1 | 0.4 | GO:2000048 | negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048) |
0.1 | 0.6 | GO:0090370 | negative regulation of cholesterol efflux(GO:0090370) |
0.1 | 0.4 | GO:0061141 | lung ciliated cell differentiation(GO:0061141) |
0.1 | 0.9 | GO:0032876 | negative regulation of DNA endoreduplication(GO:0032876) |
0.1 | 0.2 | GO:0070682 | proteasome regulatory particle assembly(GO:0070682) |
0.1 | 0.6 | GO:2000298 | regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298) |
0.1 | 0.6 | GO:0061084 | negative regulation of protein refolding(GO:0061084) |
0.1 | 0.2 | GO:1902567 | immune complex clearance by monocytes and macrophages(GO:0002436) astrocyte chemotaxis(GO:0035700) regulation of immune complex clearance by monocytes and macrophages(GO:0090264) positive regulation of immune complex clearance by monocytes and macrophages(GO:0090265) negative regulation of eosinophil activation(GO:1902567) positive regulation of CD8-positive, alpha-beta T cell extravasation(GO:2000451) regulation of astrocyte chemotaxis(GO:2000458) |
0.1 | 0.2 | GO:0002296 | T-helper 1 cell lineage commitment(GO:0002296) |
0.1 | 0.6 | GO:0016554 | cytidine to uridine editing(GO:0016554) |
0.1 | 0.5 | GO:0033353 | S-adenosylmethionine cycle(GO:0033353) |
0.1 | 0.3 | GO:0015676 | vanadium ion transport(GO:0015676) lead ion transport(GO:0015692) |
0.1 | 1.2 | GO:0031115 | negative regulation of microtubule polymerization(GO:0031115) |
0.0 | 0.3 | GO:0002317 | plasma cell differentiation(GO:0002317) |
0.0 | 0.6 | GO:0034244 | negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244) |
0.0 | 0.6 | GO:0071318 | cellular response to ATP(GO:0071318) |
0.0 | 0.9 | GO:0001539 | cilium or flagellum-dependent cell motility(GO:0001539) cilium-dependent cell motility(GO:0060285) |
0.0 | 0.1 | GO:0046022 | regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022) |
0.0 | 0.2 | GO:0034421 | post-translational protein acetylation(GO:0034421) |
0.0 | 0.2 | GO:0042706 | eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552) |
0.0 | 0.3 | GO:1903405 | protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) protein localization to nucleoplasm(GO:1990173) |
0.0 | 0.3 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
0.0 | 0.6 | GO:0045116 | protein neddylation(GO:0045116) |
0.0 | 1.0 | GO:0010501 | RNA secondary structure unwinding(GO:0010501) |
0.0 | 0.3 | GO:0033327 | Leydig cell differentiation(GO:0033327) |
0.0 | 0.2 | GO:0032525 | somite rostral/caudal axis specification(GO:0032525) |
0.0 | 0.2 | GO:0048280 | vesicle fusion with Golgi apparatus(GO:0048280) |
0.0 | 0.3 | GO:0001580 | detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580) |
0.0 | 0.2 | GO:0060837 | blood vessel endothelial cell differentiation(GO:0060837) |
0.0 | 0.1 | GO:1902018 | negative regulation of cilium assembly(GO:1902018) |
0.0 | 0.2 | GO:0060965 | negative regulation of gene silencing by miRNA(GO:0060965) |
0.0 | 0.5 | GO:0046470 | phosphatidylcholine metabolic process(GO:0046470) |
0.0 | 0.3 | GO:0007252 | I-kappaB phosphorylation(GO:0007252) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.8 | 4.1 | GO:0097226 | sperm mitochondrial sheath(GO:0097226) |
0.1 | 1.0 | GO:0097512 | cardiac myofibril(GO:0097512) |
0.1 | 0.8 | GO:0071598 | neuronal ribonucleoprotein granule(GO:0071598) |
0.1 | 0.4 | GO:0016035 | zeta DNA polymerase complex(GO:0016035) |
0.1 | 0.3 | GO:0070826 | paraferritin complex(GO:0070826) |
0.0 | 0.6 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
0.0 | 0.4 | GO:0035985 | senescence-associated heterochromatin focus(GO:0035985) |
0.0 | 0.3 | GO:0046696 | lipopolysaccharide receptor complex(GO:0046696) |
0.0 | 0.4 | GO:0042612 | MHC class I protein complex(GO:0042612) |
0.0 | 0.3 | GO:0005832 | chaperonin-containing T-complex(GO:0005832) |
0.0 | 1.2 | GO:0044295 | axonal growth cone(GO:0044295) |
0.0 | 0.2 | GO:0008540 | proteasome regulatory particle, base subcomplex(GO:0008540) |
0.0 | 0.2 | GO:0031618 | nuclear pericentric heterochromatin(GO:0031618) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.6 | 3.5 | GO:0002135 | CTP binding(GO:0002135) |
0.4 | 3.2 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
0.2 | 1.0 | GO:0015410 | manganese-transporting ATPase activity(GO:0015410) |
0.2 | 1.2 | GO:0032767 | copper-dependent protein binding(GO:0032767) |
0.2 | 0.7 | GO:0004647 | phosphoserine phosphatase activity(GO:0004647) |
0.2 | 0.6 | GO:0052739 | phosphatidylserine 1-acylhydrolase activity(GO:0052739) 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740) |
0.2 | 0.6 | GO:0032564 | dATP binding(GO:0032564) |
0.1 | 0.8 | GO:0001069 | regulatory region RNA binding(GO:0001069) |
0.1 | 0.8 | GO:0016018 | cyclosporin A binding(GO:0016018) |
0.1 | 0.4 | GO:0008073 | ornithine decarboxylase inhibitor activity(GO:0008073) |
0.1 | 0.7 | GO:0055131 | C3HC4-type RING finger domain binding(GO:0055131) |
0.1 | 2.7 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
0.1 | 0.2 | GO:0035717 | chemokine (C-C motif) ligand 7 binding(GO:0035717) |
0.1 | 0.3 | GO:0031849 | olfactory receptor binding(GO:0031849) |
0.1 | 0.3 | GO:0045131 | pre-mRNA branch point binding(GO:0045131) |
0.1 | 0.5 | GO:0016802 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
0.1 | 0.6 | GO:0046790 | virion binding(GO:0046790) |
0.1 | 0.3 | GO:0015639 | cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639) |
0.1 | 0.4 | GO:0019788 | NEDD8 transferase activity(GO:0019788) |
0.0 | 0.2 | GO:0008502 | melatonin receptor activity(GO:0008502) |
0.0 | 0.5 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
0.0 | 0.3 | GO:0035662 | Toll-like receptor 4 binding(GO:0035662) |
0.0 | 0.5 | GO:0015187 | glycine transmembrane transporter activity(GO:0015187) |
0.0 | 0.3 | GO:0004652 | polynucleotide adenylyltransferase activity(GO:0004652) |
0.0 | 0.4 | GO:0030881 | beta-2-microglobulin binding(GO:0030881) |
0.0 | 0.6 | GO:0102391 | decanoate--CoA ligase activity(GO:0102391) |
0.0 | 0.6 | GO:0005149 | interleukin-1 receptor binding(GO:0005149) |
0.0 | 0.4 | GO:1990226 | histone methyltransferase binding(GO:1990226) |
0.0 | 0.2 | GO:0004468 | lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468) |
0.0 | 0.1 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
0.0 | 0.5 | GO:0030742 | GTP-dependent protein binding(GO:0030742) |
0.0 | 1.0 | GO:0003743 | translation initiation factor activity(GO:0003743) |
0.0 | 0.2 | GO:0019869 | chloride channel inhibitor activity(GO:0019869) |
0.0 | 0.4 | GO:0008432 | JUN kinase binding(GO:0008432) |
0.0 | 0.6 | GO:0043531 | ADP binding(GO:0043531) |
0.0 | 0.2 | GO:0003956 | NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 4.1 | PID ERBB NETWORK PATHWAY | ErbB receptor signaling network |
0.0 | 1.2 | PID P38 MK2 PATHWAY | p38 signaling mediated by MAPKAP kinases |
0.0 | 0.9 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
0.0 | 1.2 | PID AR TF PATHWAY | Regulation of Androgen receptor activity |
0.0 | 1.2 | PID REG GR PATHWAY | Glucocorticoid receptor regulatory network |
0.0 | 0.7 | PID PLK1 PATHWAY | PLK1 signaling events |
0.0 | 0.3 | PID AURORA A PATHWAY | Aurora A signaling |
0.0 | 0.6 | PID IL6 7 PATHWAY | IL6-mediated signaling events |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 4.1 | REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION | Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation |
0.1 | 0.6 | REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA | Genes involved in Activation of Chaperone Genes by ATF6-alpha |
0.1 | 0.4 | REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC | Genes involved in Regulation of ornithine decarboxylase (ODC) |
0.0 | 0.6 | REACTOME IRAK1 RECRUITS IKK COMPLEX | Genes involved in IRAK1 recruits IKK complex |
0.0 | 1.0 | REACTOME DEADENYLATION OF MRNA | Genes involved in Deadenylation of mRNA |
0.0 | 0.2 | REACTOME BETA DEFENSINS | Genes involved in Beta defensins |
0.0 | 0.7 | REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION | Genes involved in Amino acid synthesis and interconversion (transamination) |
0.0 | 1.0 | REACTOME ION TRANSPORT BY P TYPE ATPASES | Genes involved in Ion transport by P-type ATPases |
0.0 | 0.3 | REACTOME PROCESSING OF INTRONLESS PRE MRNAS | Genes involved in Processing of Intronless Pre-mRNAs |
0.0 | 0.9 | REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 | Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0) |
0.0 | 0.3 | REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC | Genes involved in Formation of tubulin folding intermediates by CCT/TriC |
0.0 | 0.9 | REACTOME MEIOTIC SYNAPSIS | Genes involved in Meiotic Synapsis |