avrg: GSE58827: Dynamics of the Mouse Liver
Gene Symbol | Gene ID | Gene Info |
---|---|---|
Zbtb7c
|
ENSMUSG00000044646.8 | zinc finger and BTB domain containing 7C |
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Zbtb7c | mm10_v2_chr18_+_76059458_76059501 | 0.55 | 4.7e-04 | Click! |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.8 | 2.3 | GO:0098928 | presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526) |
0.5 | 2.5 | GO:0031444 | regulation of twitch skeletal muscle contraction(GO:0014724) slow-twitch skeletal muscle fiber contraction(GO:0031444) |
0.5 | 3.4 | GO:0045110 | intermediate filament bundle assembly(GO:0045110) |
0.4 | 1.8 | GO:0002025 | vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025) |
0.4 | 1.1 | GO:0031660 | regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) |
0.3 | 1.3 | GO:0021812 | neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812) |
0.3 | 0.9 | GO:0002019 | regulation of renal output by angiotensin(GO:0002019) |
0.2 | 1.2 | GO:0002225 | positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803) |
0.2 | 1.8 | GO:0030263 | apoptotic chromosome condensation(GO:0030263) |
0.2 | 0.9 | GO:0072054 | establishment or maintenance of polarity of embryonic epithelium(GO:0016332) renal outer medulla development(GO:0072054) inner medullary collecting duct development(GO:0072061) |
0.2 | 1.9 | GO:0000042 | protein targeting to Golgi(GO:0000042) |
0.2 | 1.6 | GO:0019336 | phenol-containing compound catabolic process(GO:0019336) |
0.2 | 0.5 | GO:2000312 | regulation of kainate selective glutamate receptor activity(GO:2000312) |
0.1 | 2.3 | GO:0048304 | positive regulation of isotype switching to IgG isotypes(GO:0048304) |
0.1 | 0.6 | GO:0044340 | canonical Wnt signaling pathway involved in regulation of cell proliferation(GO:0044340) |
0.1 | 2.0 | GO:0045830 | positive regulation of isotype switching(GO:0045830) negative regulation of double-strand break repair via homologous recombination(GO:2000042) |
0.1 | 0.4 | GO:1904742 | regulation of telomeric DNA binding(GO:1904742) |
0.1 | 1.7 | GO:0043485 | endosome to melanosome transport(GO:0035646) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757) |
0.1 | 0.6 | GO:0002175 | protein localization to paranode region of axon(GO:0002175) |
0.1 | 0.4 | GO:0003221 | right ventricular cardiac muscle tissue morphogenesis(GO:0003221) |
0.1 | 1.3 | GO:2000465 | regulation of glycogen (starch) synthase activity(GO:2000465) |
0.1 | 0.4 | GO:0035694 | mitochondrial protein catabolic process(GO:0035694) |
0.1 | 2.1 | GO:0045109 | intermediate filament organization(GO:0045109) |
0.1 | 4.3 | GO:0006779 | porphyrin-containing compound biosynthetic process(GO:0006779) |
0.1 | 0.6 | GO:0007296 | vitellogenesis(GO:0007296) |
0.1 | 0.8 | GO:0001867 | complement activation, lectin pathway(GO:0001867) |
0.1 | 0.6 | GO:0051013 | microtubule severing(GO:0051013) |
0.1 | 0.4 | GO:1904058 | positive regulation of sensory perception of pain(GO:1904058) |
0.1 | 0.2 | GO:0090204 | protein localization to nuclear pore(GO:0090204) |
0.1 | 0.8 | GO:0006002 | fructose 6-phosphate metabolic process(GO:0006002) |
0.1 | 0.4 | GO:0072718 | response to cisplatin(GO:0072718) |
0.1 | 0.8 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
0.1 | 0.4 | GO:1902748 | positive regulation of lens fiber cell differentiation(GO:1902748) |
0.1 | 0.3 | GO:1904923 | regulation of mitophagy in response to mitochondrial depolarization(GO:1904923) |
0.1 | 0.4 | GO:2001170 | negative regulation of ATP biosynthetic process(GO:2001170) |
0.0 | 0.3 | GO:0016185 | synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185) |
0.0 | 0.2 | GO:0010694 | positive regulation of alkaline phosphatase activity(GO:0010694) |
0.0 | 0.1 | GO:0007521 | muscle cell fate determination(GO:0007521) |
0.0 | 0.3 | GO:0034393 | positive regulation of smooth muscle cell apoptotic process(GO:0034393) |
0.0 | 0.8 | GO:0007202 | activation of phospholipase C activity(GO:0007202) |
0.0 | 1.4 | GO:0010831 | positive regulation of myotube differentiation(GO:0010831) |
0.0 | 0.7 | GO:0048172 | regulation of short-term neuronal synaptic plasticity(GO:0048172) |
0.0 | 0.3 | GO:0010793 | regulation of mRNA export from nucleus(GO:0010793) |
0.0 | 3.2 | GO:0032024 | positive regulation of insulin secretion(GO:0032024) |
0.0 | 0.3 | GO:0001574 | ganglioside biosynthetic process(GO:0001574) |
0.0 | 2.5 | GO:0030433 | ER-associated ubiquitin-dependent protein catabolic process(GO:0030433) |
0.0 | 0.7 | GO:0043153 | entrainment of circadian clock by photoperiod(GO:0043153) |
0.0 | 1.9 | GO:2000179 | positive regulation of neural precursor cell proliferation(GO:2000179) |
0.0 | 0.3 | GO:0030150 | protein import into mitochondrial matrix(GO:0030150) |
0.0 | 0.8 | GO:0000387 | spliceosomal snRNP assembly(GO:0000387) |
0.0 | 0.1 | GO:0034720 | histone H3-K4 demethylation(GO:0034720) |
0.0 | 0.8 | GO:0043551 | regulation of phosphatidylinositol 3-kinase activity(GO:0043551) |
0.0 | 0.2 | GO:0071218 | cellular response to misfolded protein(GO:0071218) |
0.0 | 0.1 | GO:0043353 | enucleate erythrocyte differentiation(GO:0043353) |
0.0 | 0.6 | GO:0048246 | macrophage chemotaxis(GO:0048246) |
0.0 | 0.3 | GO:0021702 | cerebellar Purkinje cell differentiation(GO:0021702) |
0.0 | 2.4 | GO:0071805 | potassium ion transmembrane transport(GO:0071805) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.8 | 2.3 | GO:1990257 | piccolo-bassoon transport vesicle(GO:1990257) |
0.6 | 4.3 | GO:0008091 | spectrin(GO:0008091) |
0.5 | 2.1 | GO:0043259 | laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259) |
0.3 | 2.5 | GO:0000835 | ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836) |
0.2 | 1.8 | GO:0061574 | ASAP complex(GO:0061574) |
0.2 | 0.8 | GO:0005944 | phosphatidylinositol 3-kinase complex, class IB(GO:0005944) |
0.2 | 5.5 | GO:0045095 | keratin filament(GO:0045095) |
0.2 | 0.8 | GO:0034715 | U7 snRNP(GO:0005683) pICln-Sm protein complex(GO:0034715) |
0.2 | 1.1 | GO:0005638 | lamin filament(GO:0005638) |
0.1 | 2.5 | GO:0001673 | male germ cell nucleus(GO:0001673) |
0.1 | 2.5 | GO:0032982 | muscle myosin complex(GO:0005859) myosin filament(GO:0032982) |
0.1 | 1.2 | GO:0042622 | photoreceptor outer segment membrane(GO:0042622) |
0.1 | 0.7 | GO:0032591 | dendritic spine membrane(GO:0032591) |
0.1 | 0.9 | GO:0043020 | NADPH oxidase complex(GO:0043020) |
0.1 | 1.9 | GO:0030137 | COPI-coated vesicle(GO:0030137) |
0.1 | 0.6 | GO:0031080 | nuclear pore outer ring(GO:0031080) |
0.0 | 3.8 | GO:0005882 | intermediate filament(GO:0005882) |
0.0 | 2.0 | GO:0035861 | site of double-strand break(GO:0035861) |
0.0 | 1.7 | GO:0030131 | clathrin adaptor complex(GO:0030131) |
0.0 | 1.8 | GO:0032809 | neuronal cell body membrane(GO:0032809) |
0.0 | 0.3 | GO:0005742 | mitochondrial outer membrane translocase complex(GO:0005742) |
0.0 | 0.5 | GO:0098839 | postsynaptic density membrane(GO:0098839) |
0.0 | 0.5 | GO:0005639 | integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) |
0.0 | 3.2 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
0.0 | 0.3 | GO:0000445 | THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445) |
0.0 | 7.1 | GO:0043209 | myelin sheath(GO:0043209) |
0.0 | 0.2 | GO:0032541 | cortical endoplasmic reticulum(GO:0032541) |
0.0 | 0.4 | GO:0005605 | basal lamina(GO:0005605) |
0.0 | 0.4 | GO:0097431 | mitotic spindle pole(GO:0097431) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.7 | 3.4 | GO:1990254 | keratin filament binding(GO:1990254) |
0.5 | 1.6 | GO:0004800 | thyroxine 5'-deiodinase activity(GO:0004800) |
0.4 | 1.8 | GO:0004939 | beta-adrenergic receptor activity(GO:0004939) bradykinin receptor binding(GO:0031711) |
0.3 | 2.0 | GO:0061649 | ubiquitinated histone binding(GO:0061649) |
0.3 | 1.3 | GO:2001069 | glycogen binding(GO:2001069) |
0.2 | 2.1 | GO:0043208 | glycosphingolipid binding(GO:0043208) |
0.2 | 0.9 | GO:1902379 | chemoattractant activity involved in axon guidance(GO:1902379) |
0.2 | 0.8 | GO:0060072 | large conductance calcium-activated potassium channel activity(GO:0060072) |
0.2 | 0.8 | GO:0030280 | structural constituent of epidermis(GO:0030280) |
0.1 | 0.6 | GO:0031727 | CCR2 chemokine receptor binding(GO:0031727) |
0.1 | 2.5 | GO:1904264 | ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264) |
0.1 | 2.5 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
0.1 | 4.3 | GO:0030506 | ankyrin binding(GO:0030506) |
0.1 | 2.4 | GO:0001222 | transcription corepressor binding(GO:0001222) |
0.1 | 0.8 | GO:0046935 | 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935) |
0.1 | 0.6 | GO:0008568 | microtubule-severing ATPase activity(GO:0008568) |
0.1 | 0.9 | GO:0016175 | superoxide-generating NADPH oxidase activity(GO:0016175) |
0.1 | 0.5 | GO:0035381 | extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381) |
0.1 | 1.1 | GO:0015271 | outward rectifier potassium channel activity(GO:0015271) |
0.0 | 0.3 | GO:0015288 | porin activity(GO:0015288) |
0.0 | 4.3 | GO:0097110 | scaffold protein binding(GO:0097110) |
0.0 | 1.2 | GO:0004190 | aspartic-type endopeptidase activity(GO:0004190) |
0.0 | 1.1 | GO:0005521 | lamin binding(GO:0005521) |
0.0 | 0.8 | GO:0008253 | 5'-nucleotidase activity(GO:0008253) |
0.0 | 0.4 | GO:0043262 | adenosine-diphosphatase activity(GO:0043262) |
0.0 | 0.2 | GO:0019788 | NEDD8 transferase activity(GO:0019788) |
0.0 | 1.1 | GO:0043274 | phospholipase binding(GO:0043274) |
0.0 | 0.3 | GO:0031749 | D2 dopamine receptor binding(GO:0031749) |
0.0 | 0.5 | GO:0070679 | inositol 1,4,5 trisphosphate binding(GO:0070679) |
0.0 | 0.8 | GO:0008483 | transaminase activity(GO:0008483) |
0.0 | 0.8 | GO:0008188 | neuropeptide receptor activity(GO:0008188) |
0.0 | 0.1 | GO:0032453 | histone demethylase activity (H3-K4 specific)(GO:0032453) |
0.0 | 0.4 | GO:0032454 | histone demethylase activity (H3-K9 specific)(GO:0032454) |
0.0 | 1.2 | GO:0004722 | protein serine/threonine phosphatase activity(GO:0004722) |
0.0 | 0.4 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
0.0 | 5.8 | GO:0005525 | GTP binding(GO:0005525) |
0.0 | 2.2 | GO:0016810 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds(GO:0016810) |
0.0 | 0.6 | GO:0042169 | SH2 domain binding(GO:0042169) |
0.0 | 0.6 | GO:0005109 | frizzled binding(GO:0005109) |
0.0 | 0.5 | GO:0035255 | ionotropic glutamate receptor binding(GO:0035255) |
0.0 | 0.7 | GO:0030374 | ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374) |
0.0 | 0.7 | GO:0005249 | voltage-gated potassium channel activity(GO:0005249) |
0.0 | 1.9 | GO:0044325 | ion channel binding(GO:0044325) |
0.0 | 0.3 | GO:0008373 | sialyltransferase activity(GO:0008373) |
0.0 | 1.3 | GO:0030165 | PDZ domain binding(GO:0030165) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 2.1 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
0.1 | 3.4 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
0.0 | 1.8 | PID ARF6 PATHWAY | Arf6 signaling events |
0.0 | 0.9 | PID WNT SIGNALING PATHWAY | Wnt signaling network |
0.0 | 1.7 | PID ECADHERIN NASCENT AJ PATHWAY | E-cadherin signaling in the nascent adherens junction |
0.0 | 0.9 | PID WNT NONCANONICAL PATHWAY | Noncanonical Wnt signaling pathway |
0.0 | 0.7 | PID INSULIN GLUCOSE PATHWAY | Insulin-mediated glucose transport |
0.0 | 0.8 | PID EPHA FWDPATHWAY | EPHA forward signaling |
0.0 | 0.7 | PID RET PATHWAY | Signaling events regulated by Ret tyrosine kinase |
0.0 | 1.1 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
0.0 | 0.3 | PID EPHRINB REV PATHWAY | Ephrin B reverse signaling |
0.0 | 0.9 | PID RAC1 PATHWAY | RAC1 signaling pathway |
0.0 | 0.8 | NABA COLLAGENS | Genes encoding collagen proteins |
0.0 | 0.2 | PID ERB GENOMIC PATHWAY | Validated nuclear estrogen receptor beta network |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 3.6 | REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION | Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression |
0.1 | 2.2 | REACTOME CRMPS IN SEMA3A SIGNALING | Genes involved in CRMPs in Sema3A signaling |
0.1 | 4.3 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
0.1 | 1.6 | REACTOME AMINE DERIVED HORMONES | Genes involved in Amine-derived hormones |
0.1 | 0.8 | REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS | Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs |
0.0 | 0.8 | REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS | Genes involved in Synthesis of substrates in N-glycan biosythesis |
0.0 | 1.8 | REACTOME AMINE LIGAND BINDING RECEPTORS | Genes involved in Amine ligand-binding receptors |
0.0 | 1.8 | REACTOME VOLTAGE GATED POTASSIUM CHANNELS | Genes involved in Voltage gated Potassium channels |
0.0 | 3.0 | REACTOME L1CAM INTERACTIONS | Genes involved in L1CAM interactions |
0.0 | 0.6 | REACTOME CTNNB1 PHOSPHORYLATION CASCADE | Genes involved in Beta-catenin phosphorylation cascade |
0.0 | 0.7 | REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS | Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
0.0 | 0.9 | REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS | Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis |
0.0 | 0.6 | REACTOME SIGNALING BY HIPPO | Genes involved in Signaling by Hippo |
0.0 | 0.6 | REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN | Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein |
0.0 | 0.3 | REACTOME N GLYCAN ANTENNAE ELONGATION | Genes involved in N-Glycan antennae elongation |
0.0 | 0.8 | REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE | Genes involved in Synthesis of PIPs at the plasma membrane |
0.0 | 0.5 | REACTOME TIGHT JUNCTION INTERACTIONS | Genes involved in Tight junction interactions |