Project

avrg: GSE58827: Dynamics of the Mouse Liver

Navigation
Downloads

Results for Zfp423

Z-value: 0.44

Motif logo

Transcription factors associated with Zfp423

Gene Symbol Gene ID Gene Info
ENSMUSG00000045333.9 zinc finger protein 423

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Zfp423mm10_v2_chr8_-_87959560_879595950.261.2e-01Click!

Activity profile of Zfp423 motif

Sorted Z-values of Zfp423 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Zfp423

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 GO:0060022 hard palate development(GO:0060022)
0.1 0.4 GO:0097477 lateral motor column neuron migration(GO:0097477)
0.1 0.6 GO:0046654 10-formyltetrahydrofolate metabolic process(GO:0009256) tetrahydrofolate biosynthetic process(GO:0046654)
0.1 0.4 GO:0032805 positive regulation of low-density lipoprotein particle receptor catabolic process(GO:0032805)
0.1 0.4 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.1 0.2 GO:0051885 positive regulation of anagen(GO:0051885)
0.1 0.3 GO:2001183 negative regulation of interleukin-12 secretion(GO:2001183)
0.1 0.3 GO:1901252 regulation of intracellular transport of viral material(GO:1901252)
0.1 0.3 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.1 0.3 GO:1900147 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.1 0.2 GO:2000402 negative regulation of lymphocyte migration(GO:2000402)
0.0 1.9 GO:0090022 regulation of neutrophil chemotaxis(GO:0090022)
0.0 0.3 GO:0072104 glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104)
0.0 1.4 GO:0046852 positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.0 0.2 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.0 0.4 GO:0033085 negative regulation of T cell differentiation in thymus(GO:0033085) positive regulation of thymocyte apoptotic process(GO:0070245) negative regulation of thymocyte aggregation(GO:2000399)
0.0 0.1 GO:0014873 response to muscle activity involved in regulation of muscle adaptation(GO:0014873) response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.0 0.2 GO:0014054 positive regulation of gamma-aminobutyric acid secretion(GO:0014054)
0.0 0.2 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.0 0.4 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.0 0.1 GO:0009750 response to fructose(GO:0009750)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.6 GO:1900273 positive regulation of long-term synaptic potentiation(GO:1900273)
0.0 0.5 GO:0045730 respiratory burst(GO:0045730)
0.0 0.1 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.0 0.1 GO:2001032 cell quiescence(GO:0044838) regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.0 0.1 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.1 GO:0006013 mannose metabolic process(GO:0006013)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.1 0.2 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.6 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.2 GO:0032280 symmetric synapse(GO:0032280)
0.0 0.5 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.2 GO:0035841 new growing cell tip(GO:0035841)
0.0 0.3 GO:0045098 type III intermediate filament(GO:0045098)
0.0 0.5 GO:0071565 nBAF complex(GO:0071565)
0.0 1.9 GO:0030863 cortical cytoskeleton(GO:0030863)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.2 0.6 GO:0004488 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
0.1 0.8 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.1 0.3 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.1 0.4 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 2.0 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.1 0.3 GO:1990254 keratin filament binding(GO:1990254)
0.1 0.5 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 0.2 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.0 0.1 GO:0008107 galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.0 0.4 GO:0008430 selenium binding(GO:0008430)
0.0 0.3 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.6 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.1 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.0 0.2 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 1.0 GO:0016504 peptidase activator activity(GO:0016504)
0.0 0.1 GO:0005131 growth hormone receptor binding(GO:0005131)
0.0 0.3 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.5 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.1 GO:0070095 fructose-6-phosphate binding(GO:0070095)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.7 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.1 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.3 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.3 REACTOME SIGNALING BY NOTCH3 Genes involved in Signaling by NOTCH3
0.0 1.4 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 1.0 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 1.0 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.5 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis