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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for AGCAGCG

Z-value: 0.46

Motif logo

miRNA associated with seed AGCAGCG

NamemiRBASE accession
MIMAT0003188

Activity profile of AGCAGCG motif

Sorted Z-values of AGCAGCG motif

Network of associatons between targets according to the STRING database.

First level regulatory network of AGCAGCG

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0015744 succinate transport(GO:0015744)
0.2 0.5 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.1 0.3 GO:0043396 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) positive regulation of corticotropin-releasing hormone secretion(GO:0051466) regulation of G-protein coupled receptor internalization(GO:1904020)
0.1 0.5 GO:0060066 oviduct development(GO:0060066)
0.1 0.3 GO:0050924 corticospinal neuron axon guidance through spinal cord(GO:0021972) positive regulation of negative chemotaxis(GO:0050924) induction of negative chemotaxis(GO:0050929) negative regulation of mononuclear cell migration(GO:0071676) negative regulation of retinal ganglion cell axon guidance(GO:0090260)
0.1 0.3 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.1 0.2 GO:0072034 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748) renal vesicle induction(GO:0072034) negative regulation of male gonad development(GO:2000019)
0.1 0.5 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.0 0.3 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.0 0.4 GO:0031179 peptide modification(GO:0031179)
0.0 0.1 GO:0099526 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
0.0 0.2 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0 0.2 GO:0010626 negative regulation of Schwann cell proliferation(GO:0010626)
0.0 0.2 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.0 0.2 GO:1904684 negative regulation of metalloendopeptidase activity(GO:1904684)
0.0 0.2 GO:0038030 non-canonical Wnt signaling pathway via MAPK cascade(GO:0038030) non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.0 1.1 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.3 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.1 GO:0006808 regulation of nitrogen utilization(GO:0006808) nitrogen utilization(GO:0019740) regulation of cellular pH reduction(GO:0032847)
0.0 0.2 GO:0018158 protein oxidation(GO:0018158)
0.0 0.2 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.1 GO:0015074 DNA integration(GO:0015074)
0.0 0.0 GO:0097534 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
0.0 0.2 GO:0042482 artery smooth muscle contraction(GO:0014824) positive regulation of odontogenesis(GO:0042482)
0.0 0.3 GO:0021692 cerebellar Purkinje cell layer morphogenesis(GO:0021692)
0.0 0.1 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.0 0.0 GO:0072014 proximal tubule development(GO:0072014)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0097149 centralspindlin complex(GO:0097149)
0.0 0.3 GO:0008091 spectrin(GO:0008091)
0.0 0.1 GO:1990257 piccolo-bassoon transport vesicle(GO:1990257)
0.0 0.1 GO:0000811 GINS complex(GO:0000811)
0.0 0.3 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 0.1 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 1.0 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.2 1.1 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.2 0.5 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.1 0.3 GO:0071936 coreceptor activity involved in Wnt signaling pathway(GO:0071936)
0.1 0.4 GO:0016842 amidine-lyase activity(GO:0016842)
0.1 0.2 GO:0004962 endothelin receptor activity(GO:0004962)
0.0 0.2 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.0 0.4 GO:0043559 insulin binding(GO:0043559)
0.0 0.3 GO:0048495 GTPase inhibitor activity(GO:0005095) Roundabout binding(GO:0048495)
0.0 0.1 GO:0001888 glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888)
0.0 0.1 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.0 0.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 1.0 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.1 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.2 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 0.4 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.0 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.0 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 0.1 GO:0051434 BH3 domain binding(GO:0051434)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 1.0 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.4 PID WNT SIGNALING PATHWAY Wnt signaling network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 1.1 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 0.8 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 1.0 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.5 REACTOME KINESINS Genes involved in Kinesins
0.0 0.3 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.2 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling