avrg: GSE58827: Dynamics of the Mouse Liver
Gene Symbol | Gene ID | Gene Info |
---|---|---|
Tfcp2
|
ENSMUSG00000009733.8 | transcription factor CP2 |
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Tfcp2 | mm10_v2_chr15_-_100551959_100552010 | 0.32 | 5.5e-02 | Click! |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
4.6 | 13.8 | GO:0006592 | ornithine biosynthetic process(GO:0006592) |
4.2 | 12.6 | GO:0002842 | positive regulation of T cell mediated immune response to tumor cell(GO:0002842) |
3.5 | 10.4 | GO:0070488 | neutrophil aggregation(GO:0070488) |
3.3 | 9.8 | GO:0043988 | histone H3-S28 phosphorylation(GO:0043988) |
3.1 | 12.3 | GO:0060912 | cardiac cell fate specification(GO:0060912) |
2.8 | 13.9 | GO:0071104 | response to interleukin-9(GO:0071104) response to interleukin-11(GO:0071105) |
2.4 | 7.2 | GO:2000451 | immune complex clearance by monocytes and macrophages(GO:0002436) astrocyte chemotaxis(GO:0035700) regulation of immune complex clearance by monocytes and macrophages(GO:0090264) positive regulation of immune complex clearance by monocytes and macrophages(GO:0090265) negative regulation of eosinophil activation(GO:1902567) positive regulation of CD8-positive, alpha-beta T cell extravasation(GO:2000451) regulation of astrocyte chemotaxis(GO:2000458) |
2.3 | 16.0 | GO:0045654 | positive regulation of megakaryocyte differentiation(GO:0045654) |
2.3 | 6.8 | GO:0031662 | regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) histone H3-S10 phosphorylation(GO:0043987) |
2.1 | 16.6 | GO:1901750 | leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750) |
1.9 | 11.3 | GO:0019371 | cyclooxygenase pathway(GO:0019371) |
1.9 | 13.0 | GO:0010273 | detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169) |
1.8 | 10.9 | GO:0000727 | double-strand break repair via break-induced replication(GO:0000727) |
1.6 | 4.8 | GO:0002030 | inhibitory G-protein coupled receptor phosphorylation(GO:0002030) |
1.3 | 3.9 | GO:0086047 | membrane depolarization during Purkinje myocyte cell action potential(GO:0086047) positive regulation of actin filament-based movement(GO:1903116) |
1.2 | 3.7 | GO:0071922 | establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922) |
1.1 | 5.7 | GO:0019276 | UDP-N-acetylgalactosamine metabolic process(GO:0019276) |
0.9 | 3.4 | GO:0035279 | mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795) |
0.8 | 4.1 | GO:0015676 | vanadium ion transport(GO:0015676) lead ion transport(GO:0015692) |
0.8 | 4.1 | GO:0010792 | DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) |
0.8 | 3.1 | GO:0060282 | positive regulation of oocyte development(GO:0060282) |
0.7 | 12.2 | GO:0030953 | astral microtubule organization(GO:0030953) |
0.7 | 5.7 | GO:0000056 | ribosomal small subunit export from nucleus(GO:0000056) |
0.7 | 7.3 | GO:2001214 | positive regulation of vasculogenesis(GO:2001214) |
0.6 | 5.1 | GO:1900264 | regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264) |
0.6 | 3.6 | GO:0006543 | glutamine catabolic process(GO:0006543) |
0.6 | 2.4 | GO:1905077 | negative regulation of interleukin-17 secretion(GO:1905077) |
0.6 | 2.3 | GO:0010979 | regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980) positive regulation of response to alcohol(GO:1901421) |
0.6 | 2.8 | GO:0031394 | positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280) |
0.5 | 2.5 | GO:0009115 | xanthine catabolic process(GO:0009115) |
0.5 | 2.9 | GO:0010626 | negative regulation of Schwann cell proliferation(GO:0010626) |
0.5 | 10.2 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
0.5 | 2.4 | GO:0006564 | L-serine biosynthetic process(GO:0006564) |
0.5 | 1.9 | GO:0046073 | dTMP biosynthetic process(GO:0006231) dTMP metabolic process(GO:0046073) |
0.5 | 6.6 | GO:0009263 | deoxyribonucleotide biosynthetic process(GO:0009263) |
0.4 | 5.7 | GO:0000185 | activation of MAPKKK activity(GO:0000185) |
0.4 | 1.7 | GO:0072061 | inner medullary collecting duct development(GO:0072061) |
0.4 | 10.6 | GO:0045109 | intermediate filament organization(GO:0045109) |
0.4 | 1.8 | GO:0014724 | regulation of twitch skeletal muscle contraction(GO:0014724) slow-twitch skeletal muscle fiber contraction(GO:0031444) |
0.3 | 1.0 | GO:0070476 | rRNA (guanine-N7)-methylation(GO:0070476) |
0.3 | 1.0 | GO:0060722 | spongiotrophoblast cell proliferation(GO:0060720) cell proliferation involved in embryonic placenta development(GO:0060722) |
0.3 | 1.0 | GO:0097401 | synaptic vesicle lumen acidification(GO:0097401) |
0.3 | 5.4 | GO:0071803 | positive regulation of podosome assembly(GO:0071803) |
0.3 | 3.8 | GO:0035970 | peptidyl-threonine dephosphorylation(GO:0035970) |
0.3 | 1.7 | GO:2000676 | positive regulation of type B pancreatic cell apoptotic process(GO:2000676) |
0.3 | 1.7 | GO:1903378 | positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378) |
0.3 | 2.3 | GO:0042126 | nitrate metabolic process(GO:0042126) |
0.3 | 1.1 | GO:0030860 | regulation of polarized epithelial cell differentiation(GO:0030860) |
0.3 | 3.3 | GO:0038166 | angiotensin-activated signaling pathway(GO:0038166) receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628) |
0.3 | 1.3 | GO:0001692 | histamine metabolic process(GO:0001692) |
0.3 | 2.1 | GO:0045743 | positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743) |
0.2 | 2.2 | GO:0010756 | positive regulation of plasminogen activation(GO:0010756) |
0.2 | 2.1 | GO:0002158 | osteoclast proliferation(GO:0002158) |
0.2 | 1.4 | GO:0010166 | wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166) |
0.2 | 0.7 | GO:1990523 | negative regulation of SMAD protein import into nucleus(GO:0060392) endothelial cell-cell adhesion(GO:0071603) negative regulation of sensory perception of pain(GO:1904057) bone regeneration(GO:1990523) |
0.2 | 0.6 | GO:1901979 | regulation of inward rectifier potassium channel activity(GO:1901979) |
0.2 | 1.6 | GO:0031087 | deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087) |
0.2 | 3.1 | GO:0001778 | plasma membrane repair(GO:0001778) |
0.2 | 0.8 | GO:2001271 | negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271) |
0.2 | 2.2 | GO:0006527 | arginine catabolic process(GO:0006527) |
0.2 | 3.1 | GO:0035414 | negative regulation of catenin import into nucleus(GO:0035414) |
0.2 | 3.4 | GO:0002227 | innate immune response in mucosa(GO:0002227) |
0.2 | 1.6 | GO:2001181 | positive regulation of interleukin-10 secretion(GO:2001181) |
0.2 | 1.5 | GO:0002035 | brain renin-angiotensin system(GO:0002035) |
0.2 | 6.1 | GO:0090022 | regulation of neutrophil chemotaxis(GO:0090022) |
0.2 | 1.8 | GO:1901621 | negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621) |
0.2 | 1.3 | GO:0030432 | peristalsis(GO:0030432) |
0.2 | 2.9 | GO:0046339 | diacylglycerol metabolic process(GO:0046339) |
0.2 | 0.6 | GO:0070601 | centromeric sister chromatid cohesion(GO:0070601) |
0.2 | 9.4 | GO:0045776 | negative regulation of blood pressure(GO:0045776) |
0.1 | 1.0 | GO:0014816 | skeletal muscle satellite cell differentiation(GO:0014816) |
0.1 | 2.3 | GO:2001241 | positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241) |
0.1 | 1.3 | GO:0045625 | regulation of T-helper 1 cell differentiation(GO:0045625) |
0.1 | 4.5 | GO:0040034 | regulation of development, heterochronic(GO:0040034) |
0.1 | 2.5 | GO:0060575 | intestinal epithelial cell differentiation(GO:0060575) |
0.1 | 4.1 | GO:0003016 | respiratory system process(GO:0003016) |
0.1 | 1.0 | GO:0045162 | clustering of voltage-gated sodium channels(GO:0045162) |
0.1 | 4.7 | GO:0048791 | calcium ion-regulated exocytosis of neurotransmitter(GO:0048791) |
0.1 | 0.9 | GO:0032020 | ISG15-protein conjugation(GO:0032020) |
0.1 | 0.6 | GO:0090666 | scaRNA localization to Cajal body(GO:0090666) |
0.1 | 1.1 | GO:1901409 | positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409) |
0.1 | 1.3 | GO:2000465 | regulation of glycogen (starch) synthase activity(GO:2000465) |
0.1 | 0.4 | GO:1902268 | negative regulation of polyamine transmembrane transport(GO:1902268) |
0.1 | 0.3 | GO:2001045 | negative regulation of integrin-mediated signaling pathway(GO:2001045) |
0.1 | 1.7 | GO:0001833 | inner cell mass cell proliferation(GO:0001833) |
0.1 | 3.8 | GO:0035025 | positive regulation of Rho protein signal transduction(GO:0035025) |
0.1 | 2.3 | GO:0060314 | regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314) |
0.1 | 4.1 | GO:0046329 | negative regulation of JNK cascade(GO:0046329) |
0.1 | 0.5 | GO:0090306 | spindle assembly involved in meiosis(GO:0090306) |
0.1 | 0.4 | GO:0006498 | N-terminal protein lipidation(GO:0006498) |
0.1 | 4.3 | GO:0006414 | translational elongation(GO:0006414) |
0.1 | 0.5 | GO:0019348 | dolichol metabolic process(GO:0019348) |
0.1 | 1.0 | GO:0045292 | mRNA cis splicing, via spliceosome(GO:0045292) |
0.1 | 2.4 | GO:0010972 | negative regulation of G2/M transition of mitotic cell cycle(GO:0010972) |
0.1 | 0.3 | GO:0034720 | histone H3-K4 demethylation(GO:0034720) |
0.1 | 1.2 | GO:0033539 | fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539) |
0.1 | 5.7 | GO:0005977 | glycogen metabolic process(GO:0005977) cellular glucan metabolic process(GO:0006073) glucan metabolic process(GO:0044042) |
0.0 | 1.5 | GO:0019236 | response to pheromone(GO:0019236) |
0.0 | 1.4 | GO:0031424 | keratinization(GO:0031424) |
0.0 | 0.0 | GO:0043396 | corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) positive regulation of corticotropin-releasing hormone secretion(GO:0051466) |
0.0 | 0.6 | GO:0033623 | regulation of integrin activation(GO:0033623) |
0.0 | 0.3 | GO:1904871 | protein localization to nuclear body(GO:1903405) positive regulation of establishment of protein localization to telomere(GO:1904851) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) protein localization to nucleoplasm(GO:1990173) |
0.0 | 0.1 | GO:0006030 | chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032) |
0.0 | 1.9 | GO:0009954 | proximal/distal pattern formation(GO:0009954) |
0.0 | 10.0 | GO:0010466 | negative regulation of peptidase activity(GO:0010466) |
0.0 | 1.7 | GO:0042462 | eye photoreceptor cell development(GO:0042462) |
0.0 | 2.7 | GO:0030968 | endoplasmic reticulum unfolded protein response(GO:0030968) |
0.0 | 2.3 | GO:0006611 | protein export from nucleus(GO:0006611) |
0.0 | 0.9 | GO:0007339 | binding of sperm to zona pellucida(GO:0007339) |
0.0 | 1.4 | GO:0006182 | cGMP biosynthetic process(GO:0006182) |
0.0 | 0.5 | GO:0050860 | negative regulation of T cell receptor signaling pathway(GO:0050860) |
0.0 | 1.1 | GO:0000027 | ribosomal large subunit assembly(GO:0000027) |
0.0 | 0.2 | GO:1901908 | diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911) |
0.0 | 0.8 | GO:0009303 | rRNA transcription(GO:0009303) |
0.0 | 0.5 | GO:0006744 | ubiquinone biosynthetic process(GO:0006744) |
0.0 | 0.9 | GO:0046677 | response to antibiotic(GO:0046677) |
0.0 | 0.2 | GO:0007253 | cytoplasmic sequestering of NF-kappaB(GO:0007253) |
0.0 | 0.3 | GO:0019363 | pyridine nucleotide biosynthetic process(GO:0019363) |
0.0 | 1.0 | GO:0006400 | tRNA modification(GO:0006400) |
0.0 | 2.2 | GO:0050821 | protein stabilization(GO:0050821) |
0.0 | 1.6 | GO:0042177 | negative regulation of protein catabolic process(GO:0042177) |
0.0 | 0.7 | GO:0006911 | phagocytosis, engulfment(GO:0006911) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.7 | 6.8 | GO:0000942 | condensed nuclear chromosome outer kinetochore(GO:0000942) |
1.6 | 9.8 | GO:0032133 | chromosome passenger complex(GO:0032133) |
1.3 | 6.6 | GO:0005971 | ribonucleoside-diphosphate reductase complex(GO:0005971) |
1.0 | 7.3 | GO:0031466 | Cul5-RING ubiquitin ligase complex(GO:0031466) |
0.9 | 4.7 | GO:1990769 | proximal neuron projection(GO:1990769) |
0.8 | 3.3 | GO:0099524 | region of cytosol(GO:0099522) postsynaptic cytosol(GO:0099524) |
0.8 | 4.1 | GO:0070826 | paraferritin complex(GO:0070826) |
0.7 | 3.7 | GO:0035189 | Rb-E2F complex(GO:0035189) |
0.6 | 3.8 | GO:0031314 | extrinsic component of mitochondrial inner membrane(GO:0031314) |
0.6 | 5.1 | GO:0031390 | Ctf18 RFC-like complex(GO:0031390) |
0.5 | 12.6 | GO:0031362 | anchored component of external side of plasma membrane(GO:0031362) |
0.4 | 4.9 | GO:0005642 | annulate lamellae(GO:0005642) |
0.4 | 1.7 | GO:0097450 | astrocyte end-foot(GO:0097450) |
0.4 | 2.4 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
0.4 | 3.4 | GO:0070578 | RISC-loading complex(GO:0070578) |
0.3 | 3.1 | GO:0032541 | cortical endoplasmic reticulum(GO:0032541) |
0.3 | 2.3 | GO:0030314 | junctional membrane complex(GO:0030314) |
0.2 | 1.7 | GO:0030670 | phagocytic vesicle membrane(GO:0030670) |
0.2 | 0.9 | GO:0097454 | Schwann cell microvillus(GO:0097454) |
0.2 | 10.9 | GO:0045171 | intercellular bridge(GO:0045171) |
0.2 | 5.4 | GO:0001891 | phagocytic cup(GO:0001891) |
0.2 | 0.9 | GO:1990452 | Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452) |
0.2 | 3.9 | GO:0034706 | sodium channel complex(GO:0034706) |
0.2 | 2.3 | GO:0097539 | ciliary transition fiber(GO:0097539) |
0.1 | 0.6 | GO:0036449 | cortical microtubule cytoskeleton(GO:0030981) microtubule minus-end(GO:0036449) |
0.1 | 0.5 | GO:0033185 | dolichol-phosphate-mannose synthase complex(GO:0033185) |
0.1 | 5.7 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
0.1 | 1.6 | GO:0031315 | extrinsic component of mitochondrial outer membrane(GO:0031315) |
0.1 | 1.1 | GO:0089717 | spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717) |
0.1 | 1.8 | GO:0002199 | zona pellucida receptor complex(GO:0002199) |
0.1 | 2.8 | GO:0042588 | zymogen granule(GO:0042588) |
0.1 | 9.6 | GO:0005882 | intermediate filament(GO:0005882) |
0.1 | 4.9 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
0.1 | 1.0 | GO:0005885 | Arp2/3 protein complex(GO:0005885) |
0.1 | 1.3 | GO:0031229 | integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) |
0.1 | 1.0 | GO:0042581 | specific granule(GO:0042581) |
0.1 | 1.1 | GO:0044232 | organelle membrane contact site(GO:0044232) |
0.1 | 0.6 | GO:0031415 | NatA complex(GO:0031415) |
0.1 | 1.8 | GO:0005859 | muscle myosin complex(GO:0005859) myosin filament(GO:0032982) |
0.1 | 5.3 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
0.1 | 13.0 | GO:0000793 | condensed chromosome(GO:0000793) |
0.1 | 1.8 | GO:0005689 | U12-type spliceosomal complex(GO:0005689) |
0.1 | 7.1 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
0.1 | 1.4 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
0.0 | 0.0 | GO:0097059 | CNTFR-CLCF1 complex(GO:0097059) |
0.0 | 1.5 | GO:0001533 | cornified envelope(GO:0001533) |
0.0 | 0.5 | GO:0000137 | Golgi cis cisterna(GO:0000137) |
0.0 | 0.9 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
0.0 | 3.1 | GO:0005901 | caveola(GO:0005901) |
0.0 | 1.7 | GO:0032391 | photoreceptor connecting cilium(GO:0032391) |
0.0 | 0.3 | GO:1990316 | ATG1/ULK1 kinase complex(GO:1990316) |
0.0 | 1.2 | GO:0030119 | AP-type membrane coat adaptor complex(GO:0030119) |
0.0 | 3.2 | GO:0071013 | catalytic step 2 spliceosome(GO:0071013) |
0.0 | 4.6 | GO:0031225 | anchored component of membrane(GO:0031225) |
0.0 | 3.7 | GO:0030139 | endocytic vesicle(GO:0030139) |
0.0 | 35.1 | GO:0005887 | integral component of plasma membrane(GO:0005887) |
0.0 | 5.3 | GO:0008021 | synaptic vesicle(GO:0008021) |
0.0 | 0.7 | GO:0005921 | gap junction(GO:0005921) |
0.0 | 0.2 | GO:0034098 | VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) |
0.0 | 1.8 | GO:0055037 | recycling endosome(GO:0055037) |
0.0 | 4.9 | GO:0000151 | ubiquitin ligase complex(GO:0000151) |
0.0 | 1.6 | GO:0030863 | cortical cytoskeleton(GO:0030863) |
0.0 | 0.8 | GO:0005643 | nuclear pore(GO:0005643) |
0.0 | 0.8 | GO:0000776 | kinetochore(GO:0000776) |
0.0 | 5.6 | GO:0005813 | centrosome(GO:0005813) |
0.0 | 10.7 | GO:0030054 | cell junction(GO:0030054) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
4.6 | 13.8 | GO:0004349 | glutamate 5-kinase activity(GO:0004349) glutamate-5-semialdehyde dehydrogenase activity(GO:0004350) delta1-pyrroline-5-carboxylate synthetase activity(GO:0017084) amino acid kinase activity(GO:0019202) |
3.3 | 26.4 | GO:0050786 | RAGE receptor binding(GO:0050786) |
2.4 | 7.2 | GO:0035717 | chemokine (C-C motif) ligand 7 binding(GO:0035717) |
1.7 | 6.8 | GO:0061575 | cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575) |
1.6 | 11.3 | GO:0008481 | sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050) |
1.4 | 16.6 | GO:0036374 | glutathione hydrolase activity(GO:0036374) |
1.3 | 6.6 | GO:0016728 | ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731) |
1.1 | 3.3 | GO:0008192 | RNA guanylyltransferase activity(GO:0008192) |
0.9 | 13.9 | GO:0050693 | LBD domain binding(GO:0050693) |
0.8 | 4.1 | GO:0015094 | cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639) |
0.8 | 2.4 | GO:0004647 | phosphoserine phosphatase activity(GO:0004647) |
0.8 | 12.6 | GO:0030296 | protein tyrosine kinase activator activity(GO:0030296) |
0.8 | 2.3 | GO:0098809 | nitrite reductase activity(GO:0098809) |
0.7 | 11.2 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
0.6 | 3.6 | GO:0004359 | glutaminase activity(GO:0004359) |
0.5 | 9.8 | GO:0035174 | histone serine kinase activity(GO:0035174) |
0.5 | 1.5 | GO:0004711 | ribosomal protein S6 kinase activity(GO:0004711) |
0.5 | 2.5 | GO:0016726 | aldehyde oxidase activity(GO:0004031) xanthine dehydrogenase activity(GO:0004854) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623) oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor(GO:0016726) |
0.5 | 4.9 | GO:0005049 | nuclear export signal receptor activity(GO:0005049) |
0.5 | 4.2 | GO:0061676 | importin-alpha family protein binding(GO:0061676) |
0.5 | 5.1 | GO:0003689 | DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170) |
0.4 | 2.1 | GO:0016941 | natriuretic peptide receptor activity(GO:0016941) |
0.3 | 3.4 | GO:0000340 | RNA 7-methylguanosine cap binding(GO:0000340) |
0.3 | 1.3 | GO:2001069 | glycogen binding(GO:2001069) |
0.3 | 1.3 | GO:0046870 | cadmium ion binding(GO:0046870) |
0.3 | 2.8 | GO:0047498 | calcium-dependent phospholipase A2 activity(GO:0047498) |
0.3 | 2.4 | GO:1990380 | Lys63-specific deubiquitinase activity(GO:0061578) Lys48-specific deubiquitinase activity(GO:1990380) |
0.3 | 4.1 | GO:0000014 | single-stranded DNA endodeoxyribonuclease activity(GO:0000014) |
0.3 | 1.4 | GO:0080019 | fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019) |
0.3 | 1.0 | GO:0072320 | volume-sensitive chloride channel activity(GO:0072320) |
0.2 | 2.6 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
0.2 | 1.9 | GO:0004865 | protein serine/threonine phosphatase inhibitor activity(GO:0004865) |
0.2 | 1.8 | GO:0001849 | complement component C1q binding(GO:0001849) |
0.2 | 2.9 | GO:0004143 | diacylglycerol kinase activity(GO:0004143) |
0.2 | 0.9 | GO:1902379 | chemoattractant activity involved in axon guidance(GO:1902379) |
0.2 | 2.2 | GO:0016813 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813) |
0.2 | 12.5 | GO:0015485 | cholesterol binding(GO:0015485) |
0.2 | 12.3 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
0.2 | 0.9 | GO:0050816 | phosphothreonine binding(GO:0050816) |
0.2 | 1.9 | GO:1990825 | sequence-specific mRNA binding(GO:1990825) |
0.2 | 5.7 | GO:0008376 | acetylgalactosaminyltransferase activity(GO:0008376) |
0.2 | 0.9 | GO:0042296 | ISG15 transferase activity(GO:0042296) |
0.1 | 3.1 | GO:0047555 | 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555) |
0.1 | 0.6 | GO:0015272 | ATP-activated inward rectifier potassium channel activity(GO:0015272) |
0.1 | 0.5 | GO:0004582 | dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582) |
0.1 | 2.3 | GO:0099604 | calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604) |
0.1 | 1.2 | GO:0003997 | acyl-CoA oxidase activity(GO:0003997) |
0.1 | 0.4 | GO:0008073 | ornithine decarboxylase inhibitor activity(GO:0008073) |
0.1 | 2.4 | GO:0003746 | translation elongation factor activity(GO:0003746) |
0.1 | 0.9 | GO:0004032 | alditol:NADP+ 1-oxidoreductase activity(GO:0004032) |
0.1 | 1.8 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
0.1 | 10.8 | GO:0005179 | hormone activity(GO:0005179) |
0.1 | 0.3 | GO:0071987 | WD40-repeat domain binding(GO:0071987) |
0.1 | 0.5 | GO:0048039 | ubiquinone binding(GO:0048039) |
0.1 | 10.0 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
0.1 | 2.9 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
0.1 | 1.4 | GO:0004383 | guanylate cyclase activity(GO:0004383) |
0.1 | 0.6 | GO:0051011 | microtubule minus-end binding(GO:0051011) |
0.1 | 2.3 | GO:0008536 | Ran GTPase binding(GO:0008536) |
0.1 | 2.4 | GO:0005227 | calcium activated cation channel activity(GO:0005227) |
0.1 | 1.5 | GO:0016503 | pheromone receptor activity(GO:0016503) |
0.1 | 0.3 | GO:0072542 | protein phosphatase activator activity(GO:0072542) |
0.1 | 1.8 | GO:0017134 | fibroblast growth factor binding(GO:0017134) |
0.0 | 0.3 | GO:0032453 | histone demethylase activity (H3-K4 specific)(GO:0032453) |
0.0 | 1.1 | GO:0070064 | proline-rich region binding(GO:0070064) |
0.0 | 2.6 | GO:0048487 | beta-tubulin binding(GO:0048487) |
0.0 | 0.5 | GO:0004185 | serine-type carboxypeptidase activity(GO:0004185) |
0.0 | 2.1 | GO:0042169 | SH2 domain binding(GO:0042169) |
0.0 | 0.8 | GO:0017160 | Ral GTPase binding(GO:0017160) |
0.0 | 0.6 | GO:0004596 | peptide alpha-N-acetyltransferase activity(GO:0004596) |
0.0 | 1.1 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
0.0 | 1.7 | GO:0005044 | scavenger receptor activity(GO:0005044) |
0.0 | 0.1 | GO:0004568 | chitinase activity(GO:0004568) |
0.0 | 1.7 | GO:0043022 | ribosome binding(GO:0043022) |
0.0 | 0.2 | GO:0034431 | endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) |
0.0 | 5.3 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
0.0 | 0.7 | GO:0005520 | insulin-like growth factor binding(GO:0005520) |
0.0 | 0.6 | GO:0031005 | filamin binding(GO:0031005) |
0.0 | 1.0 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
0.0 | 1.0 | GO:0005549 | odorant binding(GO:0005549) |
0.0 | 2.2 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
0.0 | 6.0 | GO:0061630 | ubiquitin protein ligase activity(GO:0061630) |
0.0 | 2.3 | GO:0020037 | heme binding(GO:0020037) |
0.0 | 2.4 | GO:0044325 | ion channel binding(GO:0044325) |
0.0 | 1.8 | GO:0003697 | single-stranded DNA binding(GO:0003697) |
0.0 | 0.6 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
0.0 | 2.5 | GO:0003705 | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705) |
0.0 | 3.0 | GO:0003714 | transcription corepressor activity(GO:0003714) |
0.0 | 0.8 | GO:0097110 | scaffold protein binding(GO:0097110) |
0.0 | 0.9 | GO:0051082 | unfolded protein binding(GO:0051082) |
0.0 | 0.8 | GO:0030507 | spectrin binding(GO:0030507) |
0.0 | 0.9 | GO:0004722 | protein serine/threonine phosphatase activity(GO:0004722) |
0.0 | 8.4 | GO:0046982 | protein heterodimerization activity(GO:0046982) |
0.0 | 1.1 | GO:0008013 | beta-catenin binding(GO:0008013) |
0.0 | 0.6 | GO:0019894 | kinesin binding(GO:0019894) |
0.0 | 0.6 | GO:0035064 | methylated histone binding(GO:0035064) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 21.4 | PID AURORA A PATHWAY | Aurora A signaling |
0.5 | 3.8 | SA REG CASCADE OF CYCLIN EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
0.4 | 11.3 | PID S1P META PATHWAY | Sphingosine 1-phosphate (S1P) pathway |
0.3 | 4.9 | PID RANBP2 PATHWAY | Sumoylation by RanBP2 regulates transcriptional repression |
0.3 | 10.4 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
0.2 | 10.5 | PID FOXM1 PATHWAY | FOXM1 transcription factor network |
0.2 | 10.8 | ST ERK1 ERK2 MAPK PATHWAY | ERK1/ERK2 MAPK Pathway |
0.2 | 2.4 | PID HIF1A PATHWAY | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha |
0.2 | 12.0 | PID E2F PATHWAY | E2F transcription factor network |
0.1 | 15.6 | PID SMAD2 3NUCLEAR PATHWAY | Regulation of nuclear SMAD2/3 signaling |
0.1 | 9.0 | PID RAC1 REG PATHWAY | Regulation of RAC1 activity |
0.1 | 1.3 | PID IL27 PATHWAY | IL27-mediated signaling events |
0.1 | 3.3 | ST WNT CA2 CYCLIC GMP PATHWAY | Wnt/Ca2+/cyclic GMP signaling. |
0.1 | 4.3 | PID HIF2PATHWAY | HIF-2-alpha transcription factor network |
0.1 | 2.8 | PID ENDOTHELIN PATHWAY | Endothelins |
0.1 | 3.8 | PID LYSOPHOSPHOLIPID PATHWAY | LPA receptor mediated events |
0.0 | 0.9 | PID MYC PATHWAY | C-MYC pathway |
0.0 | 2.0 | PID VEGFR1 2 PATHWAY | Signaling events mediated by VEGFR1 and VEGFR2 |
0.0 | 0.9 | PID WNT SIGNALING PATHWAY | Wnt signaling network |
0.0 | 1.5 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
0.0 | 0.7 | PID ARF6 PATHWAY | Arf6 signaling events |
0.0 | 0.4 | PID HEDGEHOG 2PATHWAY | Signaling events mediated by the Hedgehog family |
0.0 | 0.5 | PID IL2 STAT5 PATHWAY | IL2 signaling events mediated by STAT5 |
0.0 | 0.9 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
0.0 | 1.0 | PID CDC42 PATHWAY | CDC42 signaling events |
0.0 | 0.6 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.2 | 7.2 | REACTOME BETA DEFENSINS | Genes involved in Beta defensins |
1.0 | 16.0 | REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION | Genes involved in Apoptosis induced DNA fragmentation |
0.9 | 15.5 | REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION | Genes involved in Cyclin A/B1 associated events during G2/M transition |
0.7 | 8.0 | REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 | Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1 |
0.6 | 8.0 | REACTOME G1 S SPECIFIC TRANSCRIPTION | Genes involved in G1/S-Specific Transcription |
0.5 | 12.8 | REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION | Genes involved in Amino acid synthesis and interconversion (transamination) |
0.4 | 16.6 | REACTOME GLUTATHIONE CONJUGATION | Genes involved in Glutathione conjugation |
0.4 | 9.8 | REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX | Genes involved in Activation of the pre-replicative complex |
0.3 | 12.3 | REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
0.1 | 2.8 | REACTOME ACYL CHAIN REMODELLING OF PI | Genes involved in Acyl chain remodelling of PI |
0.1 | 3.3 | REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII | Genes involved in CREB phosphorylation through the activation of CaMKII |
0.1 | 9.8 | REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 | Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 |
0.1 | 4.8 | REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING | Genes involved in Negative regulators of RIG-I/MDA5 signaling |
0.1 | 1.6 | REACTOME G0 AND EARLY G1 | Genes involved in G0 and Early G1 |
0.1 | 1.6 | REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE | Genes involved in mRNA Decay by 5' to 3' Exoribonuclease |
0.1 | 1.6 | REACTOME PD1 SIGNALING | Genes involved in PD-1 signaling |
0.1 | 3.1 | REACTOME CGMP EFFECTS | Genes involved in cGMP effects |
0.1 | 9.7 | REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
0.1 | 2.3 | REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE | Genes involved in Cytochrome P450 - arranged by substrate type |
0.1 | 0.6 | REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES | Genes involved in Recruitment of NuMA to mitotic centrosomes |
0.1 | 1.7 | REACTOME PERK REGULATED GENE EXPRESSION | Genes involved in PERK regulated gene expression |
0.1 | 2.9 | REACTOME EFFECTS OF PIP2 HYDROLYSIS | Genes involved in Effects of PIP2 hydrolysis |
0.1 | 0.4 | REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC | Genes involved in Regulation of ornithine decarboxylase (ODC) |
0.1 | 1.7 | REACTOME ERK MAPK TARGETS | Genes involved in ERK/MAPK targets |
0.1 | 2.4 | REACTOME MRNA SPLICING MINOR PATHWAY | Genes involved in mRNA Splicing - Minor Pathway |
0.0 | 5.3 | REACTOME PEPTIDE CHAIN ELONGATION | Genes involved in Peptide chain elongation |
0.0 | 8.5 | REACTOME G ALPHA I SIGNALLING EVENTS | Genes involved in G alpha (i) signalling events |
0.0 | 3.1 | REACTOME MEIOTIC RECOMBINATION | Genes involved in Meiotic Recombination |
0.0 | 2.9 | REACTOME REGULATION OF INSULIN SECRETION | Genes involved in Regulation of Insulin Secretion |
0.0 | 3.2 | REACTOME MRNA SPLICING | Genes involved in mRNA Splicing |
0.0 | 1.0 | REACTOME MYOGENESIS | Genes involved in Myogenesis |
0.0 | 13.8 | REACTOME HEMOSTASIS | Genes involved in Hemostasis |
0.0 | 0.5 | REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS | Genes involved in Synthesis of substrates in N-glycan biosythesis |
0.0 | 0.8 | REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS | Genes involved in Transport of Ribonucleoproteins into the Host Nucleus |
0.0 | 0.6 | REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
0.0 | 4.6 | REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
0.0 | 0.6 | REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |