avrg: GSE58827: Dynamics of the Mouse Liver
Gene Symbol | Gene ID | Gene Info |
---|---|---|
Onecut1
|
ENSMUSG00000043013.9 | one cut domain, family member 1 |
Cux2
|
ENSMUSG00000042589.12 | cut-like homeobox 2 |
Cux2
|
ENSMUSG00000072641.1 | cut-like homeobox 2 |
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Onecut1 | mm10_v2_chr9_+_74861888_74861921 | 0.45 | 6.4e-03 | Click! |
Cux2 | mm10_v2_chr5_-_122049822_122049882 | -0.29 | 8.2e-02 | Click! |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.6 | 7.9 | GO:0034395 | regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395) |
2.2 | 6.7 | GO:0001868 | regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869) |
1.4 | 4.3 | GO:0006553 | lysine metabolic process(GO:0006553) |
1.4 | 5.7 | GO:0009992 | cellular water homeostasis(GO:0009992) |
0.9 | 2.8 | GO:0045013 | carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014) |
0.6 | 3.0 | GO:0070837 | dehydroascorbic acid transport(GO:0070837) |
0.5 | 3.2 | GO:0015712 | hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760) |
0.5 | 2.1 | GO:0007621 | negative regulation of female receptivity(GO:0007621) |
0.4 | 2.7 | GO:0032929 | negative regulation of superoxide anion generation(GO:0032929) |
0.4 | 5.8 | GO:0006957 | complement activation, alternative pathway(GO:0006957) |
0.3 | 2.0 | GO:0003383 | apical constriction(GO:0003383) |
0.3 | 3.2 | GO:0018298 | protein-chromophore linkage(GO:0018298) |
0.3 | 1.7 | GO:0050747 | positive regulation of lipoprotein metabolic process(GO:0050747) |
0.3 | 2.6 | GO:0097421 | liver regeneration(GO:0097421) |
0.2 | 2.6 | GO:0072615 | interleukin-17 secretion(GO:0072615) |
0.2 | 1.1 | GO:0033762 | response to glucagon(GO:0033762) |
0.2 | 0.6 | GO:0014809 | regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809) |
0.2 | 2.9 | GO:0046415 | urate metabolic process(GO:0046415) |
0.2 | 1.2 | GO:0046618 | drug export(GO:0046618) |
0.2 | 5.9 | GO:0043552 | positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552) |
0.2 | 1.4 | GO:0035887 | aortic smooth muscle cell differentiation(GO:0035887) |
0.2 | 3.2 | GO:0045792 | negative regulation of cell size(GO:0045792) |
0.1 | 0.9 | GO:0061056 | sclerotome development(GO:0061056) |
0.1 | 1.1 | GO:0001766 | membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580) |
0.1 | 1.8 | GO:0097264 | self proteolysis(GO:0097264) |
0.1 | 1.5 | GO:0015868 | purine ribonucleotide transport(GO:0015868) |
0.1 | 0.9 | GO:0072086 | specification of loop of Henle identity(GO:0072086) |
0.1 | 4.2 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) |
0.1 | 0.6 | GO:0021965 | spinal cord ventral commissure morphogenesis(GO:0021965) |
0.1 | 1.4 | GO:0007567 | parturition(GO:0007567) |
0.1 | 1.2 | GO:0021869 | forebrain ventricular zone progenitor cell division(GO:0021869) |
0.1 | 1.7 | GO:0006309 | apoptotic DNA fragmentation(GO:0006309) |
0.1 | 2.3 | GO:0014823 | response to activity(GO:0014823) |
0.1 | 1.1 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
0.1 | 0.5 | GO:0003199 | endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199) |
0.1 | 1.0 | GO:1902004 | positive regulation of beta-amyloid formation(GO:1902004) |
0.1 | 0.2 | GO:1900620 | acetylcholine biosynthetic process(GO:0008292) acetate ester biosynthetic process(GO:1900620) |
0.1 | 1.2 | GO:0016558 | protein import into peroxisome matrix(GO:0016558) |
0.1 | 0.7 | GO:0098789 | pre-mRNA cleavage required for polyadenylation(GO:0098789) |
0.1 | 1.9 | GO:0030212 | hyaluronan metabolic process(GO:0030212) |
0.0 | 0.2 | GO:0045896 | regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897) |
0.0 | 0.8 | GO:0034219 | carbohydrate transmembrane transport(GO:0034219) |
0.0 | 0.3 | GO:0031547 | brain-derived neurotrophic factor receptor signaling pathway(GO:0031547) |
0.0 | 2.9 | GO:0030032 | lamellipodium assembly(GO:0030032) |
0.0 | 0.8 | GO:0050908 | detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962) |
0.0 | 1.0 | GO:0044705 | mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705) |
0.0 | 0.9 | GO:0045723 | positive regulation of fatty acid biosynthetic process(GO:0045723) |
0.0 | 0.9 | GO:0071625 | vocalization behavior(GO:0071625) |
0.0 | 0.2 | GO:0051799 | negative regulation of hair follicle development(GO:0051799) |
0.0 | 0.3 | GO:0002051 | osteoblast fate commitment(GO:0002051) |
0.0 | 0.6 | GO:0039703 | viral RNA genome replication(GO:0039694) RNA replication(GO:0039703) |
0.0 | 1.4 | GO:0046676 | negative regulation of insulin secretion(GO:0046676) |
0.0 | 0.1 | GO:2000002 | negative regulation of DNA damage checkpoint(GO:2000002) |
0.0 | 0.3 | GO:0016998 | cell wall macromolecule catabolic process(GO:0016998) |
0.0 | 0.2 | GO:0035095 | behavioral response to nicotine(GO:0035095) |
0.0 | 3.2 | GO:0008360 | regulation of cell shape(GO:0008360) |
0.0 | 0.5 | GO:0006515 | misfolded or incompletely synthesized protein catabolic process(GO:0006515) |
0.0 | 0.2 | GO:0007128 | meiotic prophase I(GO:0007128) prophase(GO:0051324) |
0.0 | 0.2 | GO:0048664 | neuron fate determination(GO:0048664) |
0.0 | 0.0 | GO:0006657 | CDP-choline pathway(GO:0006657) |
0.0 | 0.3 | GO:0032011 | ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.6 | 7.9 | GO:0032010 | phagolysosome(GO:0032010) |
0.8 | 4.2 | GO:0038039 | G-protein coupled receptor heterodimeric complex(GO:0038039) |
0.5 | 5.8 | GO:0005579 | membrane attack complex(GO:0005579) |
0.4 | 2.6 | GO:0048237 | rough endoplasmic reticulum lumen(GO:0048237) |
0.3 | 2.0 | GO:0033269 | internode region of axon(GO:0033269) |
0.1 | 21.7 | GO:0072562 | blood microparticle(GO:0072562) |
0.1 | 1.1 | GO:0045275 | respiratory chain complex III(GO:0045275) |
0.1 | 1.2 | GO:0046581 | intercellular canaliculus(GO:0046581) |
0.1 | 1.4 | GO:0071564 | npBAF complex(GO:0071564) |
0.1 | 1.5 | GO:0005922 | connexon complex(GO:0005922) |
0.1 | 0.6 | GO:0032584 | growth cone membrane(GO:0032584) |
0.1 | 0.3 | GO:0044308 | axonal spine(GO:0044308) |
0.1 | 1.1 | GO:0030056 | hemidesmosome(GO:0030056) |
0.0 | 0.7 | GO:0043083 | synaptic cleft(GO:0043083) |
0.0 | 4.7 | GO:0031526 | brush border membrane(GO:0031526) |
0.0 | 0.7 | GO:0005847 | mRNA cleavage and polyadenylation specificity factor complex(GO:0005847) |
0.0 | 0.2 | GO:0017071 | intracellular cyclic nucleotide activated cation channel complex(GO:0017071) |
0.0 | 0.8 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
0.0 | 0.6 | GO:0031527 | filopodium membrane(GO:0031527) |
0.0 | 3.2 | GO:0001725 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
0.0 | 2.7 | GO:0030175 | filopodium(GO:0030175) |
0.0 | 3.2 | GO:0030176 | integral component of endoplasmic reticulum membrane(GO:0030176) |
0.0 | 0.6 | GO:0005942 | phosphatidylinositol 3-kinase complex(GO:0005942) |
0.0 | 3.8 | GO:0042579 | peroxisome(GO:0005777) microbody(GO:0042579) |
0.0 | 0.1 | GO:0000445 | THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445) |
0.0 | 0.9 | GO:0070469 | respiratory chain(GO:0070469) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.1 | 3.2 | GO:0050309 | glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309) |
0.9 | 5.7 | GO:0005332 | gamma-aminobutyric acid:sodium symporter activity(GO:0005332) |
0.7 | 4.2 | GO:0004965 | G-protein coupled GABA receptor activity(GO:0004965) |
0.6 | 3.0 | GO:0055056 | dehydroascorbic acid transporter activity(GO:0033300) D-glucose transmembrane transporter activity(GO:0055056) |
0.6 | 15.1 | GO:0001848 | complement binding(GO:0001848) |
0.5 | 2.6 | GO:0008142 | oxysterol binding(GO:0008142) |
0.4 | 1.7 | GO:0004531 | deoxyribonuclease II activity(GO:0004531) |
0.4 | 2.9 | GO:0016661 | oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661) |
0.2 | 2.1 | GO:0004887 | thyroid hormone receptor activity(GO:0004887) thyroid hormone binding(GO:0070324) |
0.2 | 1.4 | GO:0004957 | prostaglandin E receptor activity(GO:0004957) |
0.2 | 3.2 | GO:0019865 | immunoglobulin binding(GO:0019865) |
0.2 | 4.3 | GO:0016646 | oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646) |
0.2 | 2.3 | GO:0015217 | ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217) |
0.2 | 1.1 | GO:0017040 | ceramidase activity(GO:0017040) |
0.2 | 1.7 | GO:0008429 | phosphatidylethanolamine binding(GO:0008429) |
0.1 | 1.1 | GO:0016681 | ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681) |
0.1 | 0.7 | GO:0004971 | AMPA glutamate receptor activity(GO:0004971) |
0.1 | 0.6 | GO:0005042 | netrin receptor activity(GO:0005042) |
0.1 | 1.5 | GO:0005243 | gap junction channel activity(GO:0005243) |
0.1 | 7.9 | GO:0004869 | cysteine-type endopeptidase inhibitor activity(GO:0004869) |
0.1 | 1.1 | GO:0019911 | structural constituent of myelin sheath(GO:0019911) |
0.1 | 2.3 | GO:0030247 | pattern binding(GO:0001871) polysaccharide binding(GO:0030247) |
0.1 | 6.1 | GO:0016811 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811) |
0.1 | 1.2 | GO:0015125 | bile acid transmembrane transporter activity(GO:0015125) |
0.0 | 2.8 | GO:0001205 | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205) |
0.0 | 2.0 | GO:0032266 | phosphatidylinositol-3-phosphate binding(GO:0032266) |
0.0 | 0.2 | GO:0005052 | peroxisome matrix targeting signal-1 binding(GO:0005052) |
0.0 | 0.6 | GO:0002162 | dystroglycan binding(GO:0002162) |
0.0 | 0.3 | GO:0050694 | galactose 3-O-sulfotransferase activity(GO:0050694) |
0.0 | 0.6 | GO:0035005 | 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005) |
0.0 | 1.2 | GO:0031435 | mitogen-activated protein kinase kinase kinase binding(GO:0031435) |
0.0 | 0.9 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
0.0 | 0.3 | GO:0015386 | potassium:proton antiporter activity(GO:0015386) |
0.0 | 0.8 | GO:0004383 | guanylate cyclase activity(GO:0004383) |
0.0 | 0.2 | GO:0015016 | [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016) |
0.0 | 0.2 | GO:0015220 | choline transmembrane transporter activity(GO:0015220) choline binding(GO:0033265) |
0.0 | 1.1 | GO:0030506 | ankyrin binding(GO:0030506) |
0.0 | 0.3 | GO:0017151 | DEAD/H-box RNA helicase binding(GO:0017151) |
0.0 | 1.4 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
0.0 | 0.3 | GO:0003796 | lysozyme activity(GO:0003796) |
0.0 | 2.3 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
0.0 | 3.2 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
0.0 | 1.0 | GO:0001102 | RNA polymerase II activating transcription factor binding(GO:0001102) |
0.0 | 0.8 | GO:0015144 | carbohydrate transmembrane transporter activity(GO:0015144) carbohydrate transporter activity(GO:1901476) |
0.0 | 2.4 | GO:0017137 | Rab GTPase binding(GO:0017137) |
0.0 | 0.2 | GO:0042166 | acetylcholine binding(GO:0042166) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 10.5 | ST PHOSPHOINOSITIDE 3 KINASE PATHWAY | PI3K Pathway |
0.1 | 9.1 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
0.1 | 2.5 | PID INTEGRIN5 PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
0.1 | 21.1 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
0.1 | 2.0 | SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES | Genes related to the insulin receptor pathway |
0.0 | 2.7 | PID IL6 7 PATHWAY | IL6-mediated signaling events |
0.0 | 2.1 | PID RXR VDR PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
0.0 | 2.4 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
0.0 | 2.3 | PID MTOR 4PATHWAY | mTOR signaling pathway |
0.0 | 0.8 | PID CONE PATHWAY | Visual signal transduction: Cones |
0.0 | 0.3 | PID ALK2 PATHWAY | ALK2 signaling events |
0.0 | 1.4 | PID AR TF PATHWAY | Regulation of Androgen receptor activity |
0.0 | 0.6 | PID NETRIN PATHWAY | Netrin-mediated signaling events |
0.0 | 0.5 | ST DIFFERENTIATION PATHWAY IN PC12 CELLS | Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway. |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 2.7 | REACTOME CREATION OF C4 AND C2 ACTIVATORS | Genes involved in Creation of C4 and C2 activators |
0.3 | 6.7 | REACTOME INTRINSIC PATHWAY | Genes involved in Intrinsic Pathway |
0.2 | 5.8 | REACTOME COMPLEMENT CASCADE | Genes involved in Complement cascade |
0.2 | 5.7 | REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION | Genes involved in GABA synthesis, release, reuptake and degradation |
0.2 | 3.0 | REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS | Genes involved in Facilitative Na+-independent glucose transporters |
0.2 | 4.2 | REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |
0.1 | 3.8 | REACTOME DCC MEDIATED ATTRACTIVE SIGNALING | Genes involved in DCC mediated attractive signaling |
0.1 | 1.2 | REACTOME RECYCLING OF BILE ACIDS AND SALTS | Genes involved in Recycling of bile acids and salts |
0.1 | 3.4 | REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS | Genes involved in Caspase-mediated cleavage of cytoskeletal proteins |
0.1 | 0.2 | REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Acetylcholine Neurotransmitter Release Cycle |
0.1 | 2.0 | REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION | Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) |
0.1 | 2.8 | REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS | Genes involved in Regulation of gene expression in beta cells |
0.1 | 1.5 | REACTOME GAP JUNCTION ASSEMBLY | Genes involved in Gap junction assembly |
0.1 | 7.5 | REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | Genes involved in Response to elevated platelet cytosolic Ca2+ |
0.1 | 3.2 | REACTOME GLUCOSE TRANSPORT | Genes involved in Glucose transport |
0.1 | 1.7 | REACTOME SYNTHESIS OF PC | Genes involved in Synthesis of PC |
0.1 | 1.2 | REACTOME ACYL CHAIN REMODELLING OF PG | Genes involved in Acyl chain remodelling of PG |
0.1 | 4.7 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
0.0 | 0.7 | REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS | Genes involved in Trafficking of GluR2-containing AMPA receptors |
0.0 | 1.1 | REACTOME GLYCOSPHINGOLIPID METABOLISM | Genes involved in Glycosphingolipid metabolism |
0.0 | 1.0 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
0.0 | 2.5 | REACTOME INTEGRIN CELL SURFACE INTERACTIONS | Genes involved in Integrin cell surface interactions |
0.0 | 0.6 | REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE | Genes involved in Synthesis of PIPs at the Golgi membrane |
0.0 | 4.3 | REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES | Genes involved in Metabolism of amino acids and derivatives |
0.0 | 0.6 | REACTOME STRIATED MUSCLE CONTRACTION | Genes involved in Striated Muscle Contraction |
0.0 | 0.2 | REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS | Genes involved in Presynaptic nicotinic acetylcholine receptors |
0.0 | 0.2 | REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |