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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Zfp691

Z-value: 0.96

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Transcription factors associated with Zfp691

Gene Symbol Gene ID Gene Info
ENSMUSG00000045268.7 zinc finger protein 691

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Zfp691mm10_v2_chr4_-_119173849_119173901-0.474.2e-03Click!

Activity profile of Zfp691 motif

Sorted Z-values of Zfp691 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Zfp691

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.2 GO:0035702 monocyte homeostasis(GO:0035702)
0.7 2.0 GO:0031662 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662)
0.2 0.6 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.2 0.7 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.1 0.6 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.1 0.4 GO:0032831 positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032831)
0.1 0.3 GO:0003330 regulation of renal output by angiotensin(GO:0002019) regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331) L-lysine transport(GO:1902022)
0.1 0.5 GO:0097503 sialylation(GO:0097503)
0.1 1.3 GO:0033572 transferrin transport(GO:0033572)
0.1 0.4 GO:2000110 negative regulation of macrophage apoptotic process(GO:2000110)
0.1 0.6 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.1 0.4 GO:0034616 response to laminar fluid shear stress(GO:0034616) cellular response to laminar fluid shear stress(GO:0071499)
0.1 0.2 GO:0099548 trans-synaptic signaling by nitric oxide(GO:0099548)
0.1 1.5 GO:0097186 amelogenesis(GO:0097186)
0.1 0.5 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.0 0.2 GO:0070417 cellular response to cold(GO:0070417)
0.0 0.3 GO:0030578 PML body organization(GO:0030578)
0.0 0.1 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.7 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.6 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 1.7 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.0 0.0 GO:0061502 early endosome to recycling endosome transport(GO:0061502)
0.0 0.8 GO:0045954 positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.0 0.7 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 1.2 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.4 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.0 0.3 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 2.5 GO:0007586 digestion(GO:0007586)
0.0 0.6 GO:0008299 isoprenoid biosynthetic process(GO:0008299)
0.0 0.1 GO:0033353 sulfur amino acid catabolic process(GO:0000098) S-adenosylmethionine cycle(GO:0033353)
0.0 0.4 GO:0090382 phagosome maturation(GO:0090382)
0.0 0.1 GO:0015886 heme transport(GO:0015886)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.0 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.2 0.7 GO:0035841 new growing cell tip(GO:0035841)
0.1 1.3 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.3 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.3 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.6 GO:0005859 muscle myosin complex(GO:0005859) myosin filament(GO:0032982)
0.0 1.9 GO:0005882 intermediate filament(GO:0005882)
0.0 0.2 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.6 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.4 GO:0032588 trans-Golgi network membrane(GO:0032588)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.0 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.4 1.3 GO:0004998 transferrin receptor activity(GO:0004998)
0.2 1.5 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.1 0.4 GO:0019976 interleukin-2 binding(GO:0019976)
0.1 0.6 GO:0004985 opioid receptor activity(GO:0004985)
0.1 0.6 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1 0.6 GO:0000150 recombinase activity(GO:0000150)
0.1 0.2 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.1 1.4 GO:0001618 virus receptor activity(GO:0001618)
0.1 1.7 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 1.2 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 5.4 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.7 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.6 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 1.3 GO:0050699 WW domain binding(GO:0050699)
0.0 0.5 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.3 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 0.1 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 3.2 GO:0004519 endonuclease activity(GO:0004519)
0.0 0.3 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.4 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 0.5 GO:0008373 sialyltransferase activity(GO:0008373)
0.0 0.1 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.7 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.2 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.2 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.6 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.1 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.0 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 1.3 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.7 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 0.6 PID BARD1 PATHWAY BARD1 signaling events
0.0 2.7 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.3 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.4 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.6 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.2 2.0 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.1 0.4 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.1 5.2 REACTOME PLATELET AGGREGATION PLUG FORMATION Genes involved in Platelet Aggregation (Plug Formation)
0.0 1.3 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 0.6 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 1.4 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.5 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.4 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 1.5 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides