avrg: GSE58827: Dynamics of the Mouse Liver
Gene Symbol | Gene ID | Gene Info |
---|---|---|
Creb3
|
ENSMUSG00000028466.9 | cAMP responsive element binding protein 3 |
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Creb3 | mm10_v2_chr4_+_43562672_43562947 | 0.17 | 3.4e-01 | Click! |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
3.3 | 9.8 | GO:0036483 | neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0036483) regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903381) negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903382) |
1.5 | 6.0 | GO:0019287 | isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287) |
1.4 | 6.8 | GO:0009115 | xanthine catabolic process(GO:0009115) |
1.3 | 3.9 | GO:0060785 | regulation of apoptosis involved in tissue homeostasis(GO:0060785) |
1.2 | 17.2 | GO:0090110 | cargo loading into COPII-coated vesicle(GO:0090110) |
1.0 | 3.1 | GO:0061402 | positive regulation of transcription from RNA polymerase II promoter in response to acidic pH(GO:0061402) |
1.0 | 4.0 | GO:1904457 | positive regulation of neuronal action potential(GO:1904457) |
0.9 | 4.7 | GO:0002913 | positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913) |
0.9 | 5.4 | GO:0010730 | negative regulation of hydrogen peroxide biosynthetic process(GO:0010730) |
0.7 | 3.7 | GO:0001970 | positive regulation of activation of membrane attack complex(GO:0001970) |
0.7 | 2.1 | GO:1904057 | regulation of chronic inflammatory response to antigenic stimulus(GO:0002874) regulation of cytokine activity(GO:0060300) negative regulation of sensory perception of pain(GO:1904057) |
0.6 | 1.9 | GO:1904059 | regulation of locomotor rhythm(GO:1904059) |
0.6 | 3.6 | GO:0006616 | SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616) |
0.6 | 1.7 | GO:0006419 | alanyl-tRNA aminoacylation(GO:0006419) |
0.5 | 4.8 | GO:0006682 | galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375) |
0.5 | 2.0 | GO:0060598 | dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis(GO:0060598) |
0.5 | 2.0 | GO:0090126 | protein complex assembly involved in synapse maturation(GO:0090126) |
0.5 | 1.9 | GO:0006880 | intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577) |
0.5 | 6.3 | GO:0070131 | positive regulation of mitochondrial translation(GO:0070131) |
0.5 | 4.7 | GO:0048208 | vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) |
0.5 | 1.4 | GO:0071707 | immunoglobulin heavy chain V-D-J recombination(GO:0071707) |
0.5 | 1.4 | GO:1903168 | enzyme active site formation via L-cysteine sulfinic acid(GO:0018323) primary alcohol biosynthetic process(GO:0034309) cellular response to glyoxal(GO:0036471) glycolate biosynthetic process(GO:0046295) negative regulation of TRAIL-activated apoptotic signaling pathway(GO:1903122) regulation of pyrroline-5-carboxylate reductase activity(GO:1903167) positive regulation of pyrroline-5-carboxylate reductase activity(GO:1903168) regulation of tyrosine 3-monooxygenase activity(GO:1903176) positive regulation of tyrosine 3-monooxygenase activity(GO:1903178) L-dopa metabolic process(GO:1903184) L-dopa biosynthetic process(GO:1903185) glyoxal metabolic process(GO:1903189) regulation of L-dopa biosynthetic process(GO:1903195) positive regulation of L-dopa biosynthetic process(GO:1903197) regulation of L-dopa decarboxylase activity(GO:1903198) positive regulation of L-dopa decarboxylase activity(GO:1903200) positive regulation of cellular amino acid biosynthetic process(GO:2000284) |
0.4 | 3.7 | GO:0090166 | Golgi disassembly(GO:0090166) |
0.4 | 1.6 | GO:0006566 | threonine metabolic process(GO:0006566) |
0.4 | 2.0 | GO:0045716 | positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716) |
0.4 | 0.8 | GO:1903070 | negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070) |
0.4 | 5.2 | GO:0014850 | response to muscle activity(GO:0014850) |
0.4 | 4.3 | GO:0006995 | cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562) |
0.3 | 2.1 | GO:0006452 | translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905) |
0.3 | 1.4 | GO:0001306 | age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571) |
0.3 | 1.3 | GO:0036343 | psychomotor behavior(GO:0036343) |
0.3 | 1.3 | GO:0090298 | negative regulation of mitochondrial DNA replication(GO:0090298) |
0.3 | 1.0 | GO:1901857 | positive regulation of cellular respiration(GO:1901857) |
0.3 | 2.0 | GO:1990564 | protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592) |
0.3 | 1.0 | GO:0052055 | modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422) |
0.3 | 1.9 | GO:0032511 | late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511) |
0.3 | 1.5 | GO:0000320 | re-entry into mitotic cell cycle(GO:0000320) |
0.3 | 1.0 | GO:0035694 | mitochondrial protein catabolic process(GO:0035694) |
0.3 | 2.6 | GO:1904153 | negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153) |
0.3 | 1.8 | GO:0018158 | protein oxidation(GO:0018158) |
0.2 | 0.7 | GO:0070625 | zymogen granule exocytosis(GO:0070625) |
0.2 | 1.8 | GO:0051534 | negative regulation of NFAT protein import into nucleus(GO:0051534) |
0.2 | 2.7 | GO:0006613 | cotranslational protein targeting to membrane(GO:0006613) |
0.2 | 1.1 | GO:0035063 | nuclear speck organization(GO:0035063) |
0.2 | 0.4 | GO:0070375 | ERK5 cascade(GO:0070375) |
0.2 | 8.8 | GO:0006890 | retrograde vesicle-mediated transport, Golgi to ER(GO:0006890) |
0.2 | 0.8 | GO:0036091 | positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091) |
0.2 | 1.7 | GO:0015670 | carbon dioxide transport(GO:0015670) |
0.2 | 5.0 | GO:0035518 | histone H2A monoubiquitination(GO:0035518) |
0.2 | 1.5 | GO:0021937 | cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937) |
0.2 | 0.5 | GO:0061075 | cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871) |
0.2 | 4.3 | GO:0007252 | I-kappaB phosphorylation(GO:0007252) |
0.2 | 0.5 | GO:0035526 | retrograde transport, plasma membrane to Golgi(GO:0035526) |
0.2 | 1.3 | GO:0006689 | ganglioside catabolic process(GO:0006689) |
0.2 | 1.1 | GO:1901072 | N-acetylneuraminate catabolic process(GO:0019262) glucosamine-containing compound catabolic process(GO:1901072) |
0.2 | 6.5 | GO:0060445 | branching involved in salivary gland morphogenesis(GO:0060445) |
0.2 | 1.1 | GO:1901552 | sphingosine-1-phosphate signaling pathway(GO:0003376) positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142) |
0.2 | 7.2 | GO:0002474 | antigen processing and presentation of peptide antigen via MHC class I(GO:0002474) |
0.1 | 1.4 | GO:0048280 | vesicle fusion with Golgi apparatus(GO:0048280) |
0.1 | 0.8 | GO:0070127 | tRNA aminoacylation for mitochondrial protein translation(GO:0070127) |
0.1 | 2.1 | GO:0061525 | hindgut development(GO:0061525) |
0.1 | 2.9 | GO:0033539 | fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539) |
0.1 | 1.4 | GO:0098703 | calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035) |
0.1 | 1.8 | GO:0006620 | posttranslational protein targeting to membrane(GO:0006620) |
0.1 | 0.5 | GO:0097476 | spinal cord motor neuron migration(GO:0097476) |
0.1 | 1.6 | GO:1990118 | sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118) |
0.1 | 1.5 | GO:0006824 | cobalt ion transport(GO:0006824) |
0.1 | 1.4 | GO:0043982 | histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982) |
0.1 | 2.6 | GO:0099517 | anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517) |
0.1 | 1.6 | GO:0032525 | somite rostral/caudal axis specification(GO:0032525) |
0.1 | 2.2 | GO:0043968 | histone H2A acetylation(GO:0043968) |
0.1 | 2.3 | GO:0007141 | male meiosis I(GO:0007141) |
0.1 | 4.7 | GO:0018279 | protein N-linked glycosylation via asparagine(GO:0018279) |
0.1 | 0.3 | GO:0006436 | tryptophanyl-tRNA aminoacylation(GO:0006436) |
0.1 | 1.1 | GO:0043951 | negative regulation of cAMP-mediated signaling(GO:0043951) |
0.1 | 4.1 | GO:0050892 | intestinal absorption(GO:0050892) |
0.1 | 1.7 | GO:0048642 | negative regulation of skeletal muscle tissue development(GO:0048642) |
0.1 | 2.5 | GO:0046827 | positive regulation of protein export from nucleus(GO:0046827) |
0.1 | 4.1 | GO:0001706 | endoderm formation(GO:0001706) |
0.1 | 1.1 | GO:0009191 | ribonucleoside diphosphate catabolic process(GO:0009191) |
0.1 | 0.9 | GO:0016093 | polyprenol metabolic process(GO:0016093) |
0.1 | 1.2 | GO:0007220 | Notch receptor processing(GO:0007220) |
0.1 | 1.9 | GO:2001273 | regulation of glucose import in response to insulin stimulus(GO:2001273) |
0.1 | 1.0 | GO:0031274 | positive regulation of pseudopodium assembly(GO:0031274) |
0.1 | 0.3 | GO:0071638 | negative regulation of monocyte chemotactic protein-1 production(GO:0071638) |
0.1 | 1.5 | GO:0044126 | regulation of growth of symbiont in host(GO:0044126) |
0.1 | 2.2 | GO:0060009 | Sertoli cell development(GO:0060009) |
0.1 | 0.8 | GO:0051151 | negative regulation of smooth muscle cell differentiation(GO:0051151) |
0.1 | 0.7 | GO:0045794 | negative regulation of cell volume(GO:0045794) |
0.1 | 1.3 | GO:0015874 | norepinephrine transport(GO:0015874) |
0.1 | 1.0 | GO:0051382 | kinetochore assembly(GO:0051382) |
0.1 | 0.6 | GO:0010668 | ectodermal cell differentiation(GO:0010668) |
0.1 | 1.4 | GO:0021794 | thalamus development(GO:0021794) |
0.1 | 0.4 | GO:0006363 | termination of RNA polymerase I transcription(GO:0006363) |
0.1 | 1.6 | GO:0043277 | apoptotic cell clearance(GO:0043277) |
0.1 | 0.5 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
0.1 | 0.5 | GO:0007253 | cytoplasmic sequestering of NF-kappaB(GO:0007253) |
0.1 | 0.7 | GO:0034982 | mitochondrial protein processing(GO:0034982) |
0.1 | 1.0 | GO:0036296 | cellular response to increased oxygen levels(GO:0036295) response to increased oxygen levels(GO:0036296) |
0.1 | 0.8 | GO:0006465 | signal peptide processing(GO:0006465) |
0.1 | 0.9 | GO:2000060 | positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060) |
0.1 | 1.0 | GO:2000480 | negative regulation of cAMP-dependent protein kinase activity(GO:2000480) |
0.1 | 0.4 | GO:2000973 | regulation of pro-B cell differentiation(GO:2000973) |
0.1 | 3.4 | GO:0007157 | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157) |
0.1 | 1.4 | GO:0002091 | negative regulation of receptor internalization(GO:0002091) |
0.0 | 1.4 | GO:0033146 | regulation of intracellular estrogen receptor signaling pathway(GO:0033146) |
0.0 | 2.3 | GO:0043550 | regulation of lipid kinase activity(GO:0043550) |
0.0 | 1.6 | GO:1902230 | negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230) |
0.0 | 0.6 | GO:0035751 | regulation of lysosomal lumen pH(GO:0035751) |
0.0 | 1.4 | GO:0002369 | T cell cytokine production(GO:0002369) |
0.0 | 0.2 | GO:1903026 | negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026) |
0.0 | 0.3 | GO:2001032 | regulation of double-strand break repair via nonhomologous end joining(GO:2001032) |
0.0 | 1.1 | GO:0046854 | phosphatidylinositol phosphorylation(GO:0046854) |
0.0 | 1.5 | GO:0061512 | protein localization to cilium(GO:0061512) |
0.0 | 0.9 | GO:0009311 | oligosaccharide metabolic process(GO:0009311) |
0.0 | 1.6 | GO:0042462 | eye photoreceptor cell development(GO:0042462) |
0.0 | 1.4 | GO:0060325 | face morphogenesis(GO:0060325) |
0.0 | 0.6 | GO:0097352 | autophagosome maturation(GO:0097352) |
0.0 | 1.8 | GO:0031338 | regulation of vesicle fusion(GO:0031338) |
0.0 | 1.6 | GO:0000045 | autophagosome assembly(GO:0000045) |
0.0 | 1.2 | GO:1902476 | chloride transmembrane transport(GO:1902476) |
0.0 | 0.7 | GO:0008333 | endosome to lysosome transport(GO:0008333) |
0.0 | 0.1 | GO:0031642 | negative regulation of myelination(GO:0031642) |
0.0 | 0.5 | GO:0060324 | face development(GO:0060324) |
0.0 | 2.5 | GO:0048489 | synaptic vesicle transport(GO:0048489) establishment of synaptic vesicle localization(GO:0097480) |
0.0 | 0.2 | GO:0060770 | epithelial cell proliferation involved in prostate gland development(GO:0060767) regulation of epithelial cell proliferation involved in prostate gland development(GO:0060768) negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770) |
0.0 | 0.2 | GO:0007221 | positive regulation of transcription of Notch receptor target(GO:0007221) |
0.0 | 0.7 | GO:0006418 | tRNA aminoacylation for protein translation(GO:0006418) |
0.0 | 1.0 | GO:0030835 | negative regulation of actin filament depolymerization(GO:0030835) |
0.0 | 1.1 | GO:0007218 | neuropeptide signaling pathway(GO:0007218) |
0.0 | 1.8 | GO:0032411 | positive regulation of transporter activity(GO:0032411) |
0.0 | 0.3 | GO:0010867 | positive regulation of triglyceride biosynthetic process(GO:0010867) |
0.0 | 0.1 | GO:0036265 | RNA (guanine-N7)-methylation(GO:0036265) |
0.0 | 1.1 | GO:0007030 | Golgi organization(GO:0007030) |
0.0 | 0.7 | GO:0090630 | activation of GTPase activity(GO:0090630) |
0.0 | 0.7 | GO:0017145 | stem cell division(GO:0017145) |
0.0 | 1.2 | GO:0030203 | glycosaminoglycan metabolic process(GO:0030203) |
0.0 | 2.9 | GO:0006914 | autophagy(GO:0006914) |
0.0 | 0.1 | GO:0060628 | regulation of ER to Golgi vesicle-mediated transport(GO:0060628) |
0.0 | 0.1 | GO:0072697 | protein localization to cell cortex(GO:0072697) |
0.0 | 1.2 | GO:0008203 | cholesterol metabolic process(GO:0008203) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.5 | 7.5 | GO:0071256 | Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256) |
0.8 | 11.3 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
0.8 | 4.0 | GO:0044316 | cone cell pedicle(GO:0044316) |
0.8 | 11.5 | GO:0030127 | COPII vesicle coat(GO:0030127) |
0.7 | 5.0 | GO:0031467 | Cul7-RING ubiquitin ligase complex(GO:0031467) |
0.6 | 7.2 | GO:0042612 | MHC class I protein complex(GO:0042612) |
0.5 | 4.7 | GO:0042105 | alpha-beta T cell receptor complex(GO:0042105) |
0.4 | 3.1 | GO:0032937 | SREBP-SCAP-Insig complex(GO:0032937) |
0.4 | 5.4 | GO:0044754 | autolysosome(GO:0044754) |
0.4 | 2.3 | GO:0035032 | phosphatidylinositol 3-kinase complex, class III(GO:0035032) |
0.3 | 5.2 | GO:0008385 | IkappaB kinase complex(GO:0008385) |
0.3 | 2.5 | GO:0097413 | Lewy body(GO:0097413) |
0.3 | 1.2 | GO:0097598 | sperm cytoplasmic droplet(GO:0097598) |
0.3 | 1.4 | GO:0072487 | MSL complex(GO:0072487) |
0.3 | 4.1 | GO:0045179 | apical cortex(GO:0045179) |
0.2 | 1.4 | GO:0012507 | ER to Golgi transport vesicle membrane(GO:0012507) |
0.2 | 3.2 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
0.2 | 1.0 | GO:0070876 | SOSS complex(GO:0070876) |
0.2 | 2.1 | GO:0005642 | annulate lamellae(GO:0005642) |
0.2 | 3.2 | GO:0070971 | endoplasmic reticulum exit site(GO:0070971) |
0.2 | 0.7 | GO:0005745 | m-AAA complex(GO:0005745) |
0.2 | 0.9 | GO:0043527 | tRNA methyltransferase complex(GO:0043527) |
0.2 | 1.8 | GO:0016272 | prefoldin complex(GO:0016272) |
0.2 | 2.4 | GO:0072546 | ER membrane protein complex(GO:0072546) |
0.2 | 5.2 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
0.2 | 1.2 | GO:0070765 | gamma-secretase complex(GO:0070765) |
0.2 | 2.6 | GO:0031083 | BLOC-1 complex(GO:0031083) |
0.1 | 3.9 | GO:0031907 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
0.1 | 0.4 | GO:0055087 | Ski complex(GO:0055087) |
0.1 | 0.7 | GO:0034715 | pICln-Sm protein complex(GO:0034715) |
0.1 | 1.0 | GO:0005786 | signal recognition particle, endoplasmic reticulum targeting(GO:0005786) |
0.1 | 0.7 | GO:0005796 | Golgi lumen(GO:0005796) |
0.1 | 2.0 | GO:0036057 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
0.1 | 1.8 | GO:0030061 | mitochondrial crista(GO:0030061) |
0.1 | 1.7 | GO:0017119 | Golgi transport complex(GO:0017119) |
0.1 | 1.6 | GO:0042589 | zymogen granule membrane(GO:0042589) |
0.1 | 1.0 | GO:0005742 | mitochondrial outer membrane translocase complex(GO:0005742) |
0.1 | 2.2 | GO:1902562 | NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562) |
0.1 | 1.3 | GO:0042582 | primary lysosome(GO:0005766) azurophil granule(GO:0042582) |
0.1 | 0.3 | GO:0071595 | Nem1-Spo7 phosphatase complex(GO:0071595) |
0.1 | 0.8 | GO:0005787 | signal peptidase complex(GO:0005787) |
0.1 | 1.4 | GO:0031011 | Ino80 complex(GO:0031011) |
0.1 | 1.0 | GO:0033180 | proton-transporting V-type ATPase, V1 domain(GO:0033180) |
0.1 | 3.7 | GO:0031201 | SNARE complex(GO:0031201) |
0.1 | 0.6 | GO:0033263 | CORVET complex(GO:0033263) |
0.1 | 1.1 | GO:0005797 | Golgi medial cisterna(GO:0005797) |
0.1 | 3.5 | GO:0005801 | cis-Golgi network(GO:0005801) |
0.1 | 14.5 | GO:0005777 | peroxisome(GO:0005777) microbody(GO:0042579) |
0.1 | 0.9 | GO:0030877 | beta-catenin destruction complex(GO:0030877) |
0.1 | 0.5 | GO:0034098 | VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) |
0.1 | 3.3 | GO:0005762 | organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762) |
0.1 | 3.6 | GO:0005776 | autophagosome(GO:0005776) |
0.1 | 7.5 | GO:0055037 | recycling endosome(GO:0055037) |
0.1 | 0.2 | GO:0032783 | ELL-EAF complex(GO:0032783) |
0.0 | 0.7 | GO:0017101 | aminoacyl-tRNA synthetase multienzyme complex(GO:0017101) |
0.0 | 1.5 | GO:0005795 | Golgi stack(GO:0005795) |
0.0 | 1.2 | GO:0034364 | high-density lipoprotein particle(GO:0034364) |
0.0 | 2.4 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
0.0 | 1.8 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
0.0 | 8.1 | GO:0000139 | Golgi membrane(GO:0000139) |
0.0 | 3.1 | GO:0072562 | blood microparticle(GO:0072562) |
0.0 | 0.4 | GO:0005736 | DNA-directed RNA polymerase I complex(GO:0005736) |
0.0 | 1.7 | GO:0009925 | basal plasma membrane(GO:0009925) |
0.0 | 2.1 | GO:0032587 | ruffle membrane(GO:0032587) |
0.0 | 0.5 | GO:0045335 | phagocytic vesicle(GO:0045335) |
0.0 | 7.0 | GO:0005743 | mitochondrial inner membrane(GO:0005743) |
0.0 | 1.0 | GO:0016529 | sarcoplasmic reticulum(GO:0016529) |
0.0 | 2.7 | GO:0001650 | fibrillar center(GO:0001650) |
0.0 | 2.5 | GO:0030018 | Z disc(GO:0030018) |
0.0 | 6.3 | GO:0005764 | lytic vacuole(GO:0000323) lysosome(GO:0005764) |
0.0 | 0.8 | GO:0030864 | cortical actin cytoskeleton(GO:0030864) |
0.0 | 1.5 | GO:0005923 | bicellular tight junction(GO:0005923) |
0.0 | 1.0 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
0.0 | 0.1 | GO:0000813 | ESCRT I complex(GO:0000813) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.4 | 4.1 | GO:0008330 | protein tyrosine/threonine phosphatase activity(GO:0008330) |
1.4 | 6.8 | GO:0016623 | aldehyde oxidase activity(GO:0004031) xanthine dehydrogenase activity(GO:0004854) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623) oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor(GO:0016726) |
1.3 | 3.9 | GO:0072541 | peroxynitrite reductase activity(GO:0072541) |
1.2 | 4.8 | GO:0047275 | glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275) |
1.1 | 3.2 | GO:0042954 | lipoprotein transporter activity(GO:0042954) |
1.0 | 2.9 | GO:0017099 | very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099) |
0.6 | 4.1 | GO:0005324 | long-chain fatty acid transporter activity(GO:0005324) |
0.6 | 1.7 | GO:0004813 | alanine-tRNA ligase activity(GO:0004813) |
0.6 | 5.7 | GO:0001594 | trace-amine receptor activity(GO:0001594) |
0.6 | 7.2 | GO:0030881 | beta-2-microglobulin binding(GO:0030881) |
0.5 | 1.6 | GO:0070905 | serine binding(GO:0070905) |
0.5 | 2.7 | GO:0004768 | stearoyl-CoA 9-desaturase activity(GO:0004768) |
0.5 | 1.4 | GO:0015275 | stretch-activated, cation-selective, calcium channel activity(GO:0015275) |
0.5 | 1.4 | GO:0036470 | tyrosine 3-monooxygenase activator activity(GO:0036470) L-dopa decarboxylase activator activity(GO:0036478) |
0.4 | 1.3 | GO:0005333 | norepinephrine transmembrane transporter activity(GO:0005333) |
0.4 | 1.6 | GO:0048408 | epidermal growth factor binding(GO:0048408) |
0.4 | 2.0 | GO:0097109 | neuroligin family protein binding(GO:0097109) |
0.3 | 1.0 | GO:1990050 | phosphatidic acid transporter activity(GO:1990050) |
0.3 | 1.5 | GO:0070568 | guanylyltransferase activity(GO:0070568) |
0.3 | 3.4 | GO:0008429 | phosphatidylethanolamine binding(GO:0008429) |
0.3 | 0.9 | GO:0008176 | tRNA (guanine-N7-)-methyltransferase activity(GO:0008176) |
0.3 | 5.2 | GO:0035174 | histone serine kinase activity(GO:0035174) |
0.3 | 2.5 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
0.3 | 1.3 | GO:0004563 | beta-N-acetylhexosaminidase activity(GO:0004563) |
0.3 | 1.0 | GO:0004176 | ATP-dependent peptidase activity(GO:0004176) |
0.2 | 3.2 | GO:0004579 | oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
0.2 | 1.2 | GO:0008449 | N-acetylglucosamine-6-sulfatase activity(GO:0008449) |
0.2 | 1.1 | GO:0004382 | guanosine-diphosphatase activity(GO:0004382) |
0.2 | 5.0 | GO:0097602 | cullin family protein binding(GO:0097602) |
0.2 | 1.2 | GO:0005047 | signal recognition particle binding(GO:0005047) |
0.2 | 4.0 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
0.2 | 1.4 | GO:0046972 | histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972) |
0.2 | 9.1 | GO:0016776 | phosphotransferase activity, phosphate group as acceptor(GO:0016776) |
0.2 | 0.8 | GO:1904288 | BAT3 complex binding(GO:1904288) |
0.1 | 1.6 | GO:0015386 | potassium:proton antiporter activity(GO:0015386) |
0.1 | 1.3 | GO:0003909 | DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910) |
0.1 | 1.8 | GO:0030346 | protein phosphatase 2B binding(GO:0030346) |
0.1 | 2.1 | GO:0017070 | U6 snRNA binding(GO:0017070) |
0.1 | 1.7 | GO:0015250 | water channel activity(GO:0015250) |
0.1 | 5.1 | GO:0005484 | SNAP receptor activity(GO:0005484) |
0.1 | 3.3 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
0.1 | 0.3 | GO:0004830 | tryptophan-tRNA ligase activity(GO:0004830) |
0.1 | 1.8 | GO:0017081 | chloride channel regulator activity(GO:0017081) |
0.1 | 4.0 | GO:0030552 | cAMP binding(GO:0030552) |
0.1 | 0.3 | GO:0004045 | aminoacyl-tRNA hydrolase activity(GO:0004045) |
0.1 | 10.8 | GO:0020037 | heme binding(GO:0020037) |
0.1 | 1.1 | GO:0038036 | sphingosine-1-phosphate receptor activity(GO:0038036) |
0.1 | 1.2 | GO:0042043 | neurexin family protein binding(GO:0042043) |
0.1 | 3.6 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
0.1 | 3.5 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
0.1 | 3.4 | GO:0016831 | carboxy-lyase activity(GO:0016831) |
0.1 | 0.4 | GO:0042030 | ATPase inhibitor activity(GO:0042030) |
0.1 | 1.0 | GO:0004862 | cAMP-dependent protein kinase inhibitor activity(GO:0004862) |
0.1 | 2.7 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
0.1 | 1.3 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
0.1 | 1.5 | GO:0051787 | misfolded protein binding(GO:0051787) |
0.1 | 1.5 | GO:0070064 | proline-rich region binding(GO:0070064) |
0.1 | 0.9 | GO:0031386 | protein tag(GO:0031386) |
0.1 | 0.8 | GO:0008641 | small protein activating enzyme activity(GO:0008641) |
0.1 | 1.1 | GO:0016805 | dipeptidase activity(GO:0016805) |
0.1 | 1.3 | GO:0004745 | retinol dehydrogenase activity(GO:0004745) |
0.1 | 2.3 | GO:0016922 | ligand-dependent nuclear receptor binding(GO:0016922) |
0.1 | 0.9 | GO:0004659 | prenyltransferase activity(GO:0004659) |
0.1 | 1.8 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
0.1 | 6.2 | GO:0000149 | SNARE binding(GO:0000149) |
0.1 | 1.3 | GO:0042923 | neuropeptide binding(GO:0042923) |
0.1 | 0.9 | GO:0050811 | GABA receptor binding(GO:0050811) |
0.1 | 1.8 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
0.0 | 1.5 | GO:0015248 | sterol transporter activity(GO:0015248) |
0.0 | 1.0 | GO:0017049 | GTP-Rho binding(GO:0017049) |
0.0 | 1.5 | GO:0070566 | adenylyltransferase activity(GO:0070566) |
0.0 | 0.4 | GO:0070097 | delta-catenin binding(GO:0070097) |
0.0 | 3.5 | GO:0003724 | RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004) |
0.0 | 0.3 | GO:0030976 | thiamine pyrophosphate binding(GO:0030976) |
0.0 | 5.2 | GO:0030165 | PDZ domain binding(GO:0030165) |
0.0 | 0.4 | GO:0008484 | sulfuric ester hydrolase activity(GO:0008484) |
0.0 | 1.7 | GO:0030332 | cyclin binding(GO:0030332) |
0.0 | 1.5 | GO:0004812 | aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876) |
0.0 | 1.0 | GO:0046961 | proton-transporting ATPase activity, rotational mechanism(GO:0046961) |
0.0 | 6.2 | GO:0017124 | SH3 domain binding(GO:0017124) |
0.0 | 0.3 | GO:0034236 | protein kinase A catalytic subunit binding(GO:0034236) |
0.0 | 0.2 | GO:0015016 | [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016) |
0.0 | 0.4 | GO:0043522 | leucine zipper domain binding(GO:0043522) |
0.0 | 3.4 | GO:0008565 | protein transporter activity(GO:0008565) |
0.0 | 0.1 | GO:0004694 | eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694) |
0.0 | 0.2 | GO:0000293 | ferric-chelate reductase activity(GO:0000293) |
0.0 | 0.2 | GO:0043023 | ribosomal large subunit binding(GO:0043023) |
0.0 | 1.0 | GO:0003785 | actin monomer binding(GO:0003785) |
0.0 | 1.1 | GO:0019213 | deacetylase activity(GO:0019213) |
0.0 | 0.4 | GO:0001054 | RNA polymerase I activity(GO:0001054) |
0.0 | 0.5 | GO:0005528 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
0.0 | 0.6 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
0.0 | 1.4 | GO:0016790 | thiolester hydrolase activity(GO:0016790) |
0.0 | 1.4 | GO:0004497 | monooxygenase activity(GO:0004497) |
0.0 | 0.8 | GO:0008378 | galactosyltransferase activity(GO:0008378) |
0.0 | 0.3 | GO:0050072 | m7G(5')pppN diphosphatase activity(GO:0050072) |
0.0 | 0.7 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
0.0 | 2.1 | GO:0043130 | ubiquitin binding(GO:0043130) |
0.0 | 0.7 | GO:0017091 | AU-rich element binding(GO:0017091) |
0.0 | 1.9 | GO:0005506 | iron ion binding(GO:0005506) |
0.0 | 2.1 | GO:0070851 | growth factor receptor binding(GO:0070851) |
0.0 | 3.7 | GO:0004866 | endopeptidase inhibitor activity(GO:0004866) |
0.0 | 0.7 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
0.0 | 1.8 | GO:0042826 | histone deacetylase binding(GO:0042826) |
0.0 | 1.9 | GO:0001046 | core promoter sequence-specific DNA binding(GO:0001046) |
0.0 | 0.1 | GO:0061135 | endopeptidase regulator activity(GO:0061135) |
0.0 | 0.3 | GO:0005159 | insulin-like growth factor receptor binding(GO:0005159) |
0.0 | 1.1 | GO:0005179 | hormone activity(GO:0005179) |
0.0 | 0.7 | GO:0004843 | thiol-dependent ubiquitin-specific protease activity(GO:0004843) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 3.7 | PID ERB GENOMIC PATHWAY | Validated nuclear estrogen receptor beta network |
0.1 | 4.2 | PID ARF 3PATHWAY | Arf1 pathway |
0.1 | 6.0 | PID IL1 PATHWAY | IL1-mediated signaling events |
0.1 | 4.7 | PID IL12 STAT4 PATHWAY | IL12 signaling mediated by STAT4 |
0.1 | 2.0 | PID ERBB NETWORK PATHWAY | ErbB receptor signaling network |
0.1 | 0.8 | PID FRA PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
0.1 | 4.1 | PID P38 ALPHA BETA PATHWAY | Regulation of p38-alpha and p38-beta |
0.1 | 1.5 | SA G1 AND S PHASES | Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition. |
0.1 | 1.2 | PID SYNDECAN 3 PATHWAY | Syndecan-3-mediated signaling events |
0.1 | 5.5 | PID LKB1 PATHWAY | LKB1 signaling events |
0.1 | 1.7 | PID RB 1PATHWAY | Regulation of retinoblastoma protein |
0.1 | 1.1 | PID S1P S1P2 PATHWAY | S1P2 pathway |
0.1 | 3.1 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
0.0 | 2.5 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
0.0 | 1.3 | PID CONE PATHWAY | Visual signal transduction: Cones |
0.0 | 1.8 | PID VEGFR1 2 PATHWAY | Signaling events mediated by VEGFR1 and VEGFR2 |
0.0 | 2.7 | PID ECADHERIN STABILIZATION PATHWAY | Stabilization and expansion of the E-cadherin adherens junction |
0.0 | 1.4 | PID ALPHA SYNUCLEIN PATHWAY | Alpha-synuclein signaling |
0.0 | 2.1 | PID AP1 PATHWAY | AP-1 transcription factor network |
0.0 | 1.2 | PID HEDGEHOG GLI PATHWAY | Hedgehog signaling events mediated by Gli proteins |
0.0 | 1.4 | PID HES HEY PATHWAY | Notch-mediated HES/HEY network |
0.0 | 0.9 | ST WNT BETA CATENIN PATHWAY | Wnt/beta-catenin Pathway |
0.0 | 0.5 | PID FOXO PATHWAY | FoxO family signaling |
0.0 | 1.8 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
0.0 | 1.0 | ST FAS SIGNALING PATHWAY | Fas Signaling Pathway |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 4.7 | REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE | Genes involved in Translocation of ZAP-70 to Immunological synapse |
0.5 | 9.1 | REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC | Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC |
0.3 | 5.2 | REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK | Genes involved in Regulation of Rheb GTPase activity by AMPK |
0.3 | 3.7 | REACTOME REGULATION OF COMPLEMENT CASCADE | Genes involved in Regulation of Complement cascade |
0.2 | 6.0 | REACTOME CHOLESTEROL BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
0.2 | 3.1 | REACTOME ABACAVIR TRANSPORT AND METABOLISM | Genes involved in Abacavir transport and metabolism |
0.2 | 2.5 | REACTOME KERATAN SULFATE DEGRADATION | Genes involved in Keratan sulfate degradation |
0.2 | 2.0 | REACTOME THE ACTIVATION OF ARYLSULFATASES | Genes involved in The activation of arylsulfatases |
0.2 | 11.4 | REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S | Genes involved in Activation of Chaperone Genes by XBP1(S) |
0.2 | 1.8 | REACTOME PURINE CATABOLISM | Genes involved in Purine catabolism |
0.2 | 1.7 | REACTOME COPI MEDIATED TRANSPORT | Genes involved in COPI Mediated Transport |
0.1 | 1.7 | REACTOME PASSIVE TRANSPORT BY AQUAPORINS | Genes involved in Passive Transport by Aquaporins |
0.1 | 0.8 | REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA | Genes involved in Activation of Chaperone Genes by ATF6-alpha |
0.1 | 2.7 | REACTOME ALPHA LINOLENIC ACID ALA METABOLISM | Genes involved in alpha-linolenic acid (ALA) metabolism |
0.1 | 4.2 | REACTOME LYSOSOME VESICLE BIOGENESIS | Genes involved in Lysosome Vesicle Biogenesis |
0.1 | 4.0 | REACTOME RAP1 SIGNALLING | Genes involved in Rap1 signalling |
0.1 | 1.3 | REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY | Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway |
0.1 | 0.8 | REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION | Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation |
0.1 | 2.1 | REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION | Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation |
0.1 | 0.9 | REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE | Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle |
0.1 | 1.2 | REACTOME REGULATED PROTEOLYSIS OF P75NTR | Genes involved in Regulated proteolysis of p75NTR |
0.1 | 2.4 | REACTOME CYTOSOLIC TRNA AMINOACYLATION | Genes involved in Cytosolic tRNA aminoacylation |
0.1 | 9.9 | REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE | Genes involved in SRP-dependent cotranslational protein targeting to membrane |
0.1 | 1.6 | REACTOME PRE NOTCH PROCESSING IN GOLGI | Genes involved in Pre-NOTCH Processing in Golgi |
0.1 | 3.3 | REACTOME ION TRANSPORT BY P TYPE ATPASES | Genes involved in Ion transport by P-type ATPases |
0.1 | 1.3 | REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS | Genes involved in Na+/Cl- dependent neurotransmitter transporters |
0.1 | 1.1 | REACTOME TRNA AMINOACYLATION | Genes involved in tRNA Aminoacylation |
0.1 | 1.5 | REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI | Genes involved in N-glycan antennae elongation in the medial/trans-Golgi |
0.1 | 1.8 | REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC | Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC |
0.0 | 0.7 | REACTOME METABOLISM OF NON CODING RNA | Genes involved in Metabolism of non-coding RNA |
0.0 | 1.1 | REACTOME SULFUR AMINO ACID METABOLISM | Genes involved in Sulfur amino acid metabolism |
0.0 | 1.0 | REACTOME INSULIN RECEPTOR RECYCLING | Genes involved in Insulin receptor recycling |
0.0 | 1.5 | REACTOME G1 PHASE | Genes involved in G1 Phase |
0.0 | 1.5 | REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
0.0 | 2.3 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
0.0 | 0.4 | REACTOME INSULIN SYNTHESIS AND PROCESSING | Genes involved in Insulin Synthesis and Processing |
0.0 | 0.4 | REACTOME ERK MAPK TARGETS | Genes involved in ERK/MAPK targets |
0.0 | 3.9 | REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
0.0 | 0.1 | REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS | Genes involved in Membrane binding and targetting of GAG proteins |