avrg: GSE58827: Dynamics of the Mouse Liver
Gene Symbol | Gene ID | Gene Info |
---|---|---|
Hoxc10
|
ENSMUSG00000022484.7 | homeobox C10 |
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Hoxc10 | mm10_v2_chr15_+_102966794_102966812 | -0.03 | 8.6e-01 | Click! |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.7 | 11.0 | GO:0034760 | negative regulation of iron ion transport(GO:0034757) negative regulation of iron ion transmembrane transport(GO:0034760) |
0.8 | 4.2 | GO:2000255 | negative regulation of male germ cell proliferation(GO:2000255) |
0.8 | 3.1 | GO:0014916 | regulation of lung blood pressure(GO:0014916) |
0.7 | 2.7 | GO:0090126 | protein complex assembly involved in synapse maturation(GO:0090126) |
0.6 | 4.5 | GO:0060455 | negative regulation of gastric acid secretion(GO:0060455) |
0.6 | 2.4 | GO:0043380 | regulation of memory T cell differentiation(GO:0043380) negative regulation of isotype switching to IgE isotypes(GO:0048294) |
0.5 | 1.6 | GO:0006507 | GPI anchor release(GO:0006507) |
0.5 | 1.5 | GO:0014878 | response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878) |
0.5 | 1.5 | GO:0061026 | cardiac muscle tissue regeneration(GO:0061026) |
0.4 | 2.6 | GO:0019805 | quinolinate biosynthetic process(GO:0019805) |
0.4 | 2.6 | GO:0021912 | regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913) |
0.3 | 1.3 | GO:0070368 | positive regulation of hepatocyte differentiation(GO:0070368) |
0.3 | 0.9 | GO:0042231 | interleukin-13 biosynthetic process(GO:0042231) |
0.3 | 1.6 | GO:0006083 | acetate metabolic process(GO:0006083) |
0.3 | 5.1 | GO:0030828 | positive regulation of cGMP biosynthetic process(GO:0030828) |
0.3 | 2.8 | GO:0031441 | negative regulation of mRNA 3'-end processing(GO:0031441) |
0.2 | 0.7 | GO:0042977 | regulation of activation of JAK2 kinase activity(GO:0010534) activation of JAK2 kinase activity(GO:0042977) negative regulation of activation of JAK2 kinase activity(GO:1902569) |
0.2 | 4.2 | GO:0046069 | cGMP catabolic process(GO:0046069) |
0.2 | 0.8 | GO:0035606 | peptidyl-cysteine S-trans-nitrosylation(GO:0035606) |
0.2 | 0.7 | GO:0042271 | susceptibility to natural killer cell mediated cytotoxicity(GO:0042271) |
0.2 | 0.7 | GO:0060743 | epithelial cell maturation involved in prostate gland development(GO:0060743) |
0.1 | 2.1 | GO:0032000 | positive regulation of fatty acid beta-oxidation(GO:0032000) |
0.1 | 0.4 | GO:1900477 | negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter(GO:1900477) |
0.1 | 2.4 | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone(GO:0006120) |
0.1 | 0.7 | GO:1904936 | cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936) |
0.1 | 2.7 | GO:0060218 | hematopoietic stem cell differentiation(GO:0060218) |
0.1 | 0.3 | GO:0021934 | hindbrain tangential cell migration(GO:0021934) |
0.1 | 1.8 | GO:0000338 | protein deneddylation(GO:0000338) |
0.1 | 1.4 | GO:0071712 | ER-associated misfolded protein catabolic process(GO:0071712) |
0.1 | 2.9 | GO:0015813 | L-glutamate transport(GO:0015813) |
0.1 | 1.5 | GO:0048387 | negative regulation of retinoic acid receptor signaling pathway(GO:0048387) |
0.1 | 0.6 | GO:0051970 | negative regulation of transmission of nerve impulse(GO:0051970) |
0.1 | 0.3 | GO:0044029 | DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029) |
0.1 | 0.4 | GO:0021502 | neural fold elevation formation(GO:0021502) |
0.1 | 0.1 | GO:0060557 | positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559) |
0.1 | 0.6 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
0.1 | 0.6 | GO:0035269 | protein O-linked mannosylation(GO:0035269) |
0.1 | 1.6 | GO:0015721 | bile acid and bile salt transport(GO:0015721) |
0.1 | 1.5 | GO:0014823 | response to activity(GO:0014823) |
0.1 | 0.3 | GO:0048014 | Tie signaling pathway(GO:0048014) |
0.0 | 0.7 | GO:0090050 | positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) |
0.0 | 0.5 | GO:0007320 | insemination(GO:0007320) |
0.0 | 0.1 | GO:0003274 | endocardial cushion fusion(GO:0003274) positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563) |
0.0 | 1.4 | GO:0042036 | negative regulation of cytokine biosynthetic process(GO:0042036) |
0.0 | 0.5 | GO:1901898 | negative regulation of relaxation of cardiac muscle(GO:1901898) |
0.0 | 0.1 | GO:0098974 | postsynaptic actin cytoskeleton organization(GO:0098974) |
0.0 | 3.0 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
0.0 | 0.3 | GO:0007191 | adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191) |
0.0 | 0.3 | GO:1901621 | negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621) |
0.0 | 0.1 | GO:0097118 | neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118) |
0.0 | 0.8 | GO:0070328 | acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328) |
0.0 | 0.2 | GO:0043653 | mitochondrial fragmentation involved in apoptotic process(GO:0043653) |
0.0 | 1.6 | GO:0030500 | regulation of bone mineralization(GO:0030500) |
0.0 | 0.3 | GO:0071420 | cellular response to histamine(GO:0071420) |
0.0 | 0.7 | GO:0031648 | protein destabilization(GO:0031648) |
0.0 | 1.1 | GO:0030512 | negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) |
0.0 | 0.1 | GO:0035372 | protein localization to microtubule(GO:0035372) |
0.0 | 0.4 | GO:0035335 | peptidyl-tyrosine dephosphorylation(GO:0035335) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 5.3 | GO:0030057 | desmosome(GO:0030057) |
0.2 | 2.8 | GO:0036056 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
0.1 | 2.1 | GO:0045179 | apical cortex(GO:0045179) |
0.1 | 0.6 | GO:0033185 | dolichol-phosphate-mannose synthase complex(GO:0033185) |
0.1 | 2.8 | GO:0030014 | CCR4-NOT complex(GO:0030014) |
0.1 | 0.8 | GO:0097452 | GAIT complex(GO:0097452) |
0.1 | 0.3 | GO:0005943 | phosphatidylinositol 3-kinase complex, class IA(GO:0005943) |
0.0 | 1.6 | GO:0034364 | high-density lipoprotein particle(GO:0034364) |
0.0 | 0.6 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
0.0 | 1.1 | GO:0005614 | interstitial matrix(GO:0005614) |
0.0 | 1.8 | GO:0008180 | COP9 signalosome(GO:0008180) |
0.0 | 0.5 | GO:0036513 | Derlin-1 retrotranslocation complex(GO:0036513) |
0.0 | 1.4 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
0.0 | 3.6 | GO:0005791 | rough endoplasmic reticulum(GO:0005791) |
0.0 | 2.4 | GO:0005657 | replication fork(GO:0005657) |
0.0 | 2.5 | GO:0070469 | respiratory chain(GO:0070469) |
0.0 | 0.8 | GO:0070971 | endoplasmic reticulum exit site(GO:0070971) |
0.0 | 3.8 | GO:0043204 | perikaryon(GO:0043204) |
0.0 | 0.3 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
0.0 | 0.5 | GO:0000930 | gamma-tubulin complex(GO:0000930) |
0.0 | 1.5 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
0.0 | 2.1 | GO:0005882 | intermediate filament(GO:0005882) |
0.0 | 1.6 | GO:0000502 | proteasome complex(GO:0000502) |
0.0 | 0.3 | GO:1902711 | GABA-A receptor complex(GO:1902711) |
0.0 | 0.4 | GO:0016581 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
0.0 | 0.3 | GO:0030285 | integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563) |
0.0 | 0.3 | GO:0005766 | primary lysosome(GO:0005766) azurophil granule(GO:0042582) |
0.0 | 0.6 | GO:0060077 | inhibitory synapse(GO:0060077) |
0.0 | 1.6 | GO:0005901 | caveola(GO:0005901) |
0.0 | 5.4 | GO:0005743 | mitochondrial inner membrane(GO:0005743) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.5 | 7.6 | GO:0008390 | testosterone 16-alpha-hydroxylase activity(GO:0008390) |
1.1 | 4.2 | GO:0004667 | prostaglandin-D synthase activity(GO:0004667) |
1.0 | 4.9 | GO:0008502 | melatonin receptor activity(GO:0008502) |
0.5 | 1.6 | GO:0019807 | aspartoacylase activity(GO:0019807) |
0.5 | 3.1 | GO:0019238 | cyclohydrolase activity(GO:0019238) |
0.4 | 1.1 | GO:0050220 | prostaglandin-E synthase activity(GO:0050220) |
0.3 | 3.9 | GO:0045236 | CXCR chemokine receptor binding(GO:0045236) |
0.3 | 2.1 | GO:0005324 | long-chain fatty acid transporter activity(GO:0005324) |
0.3 | 0.8 | GO:0035605 | peptidyl-cysteine S-nitrosylase activity(GO:0035605) |
0.2 | 0.7 | GO:0070540 | stearic acid binding(GO:0070540) |
0.2 | 1.6 | GO:0008508 | bile acid:sodium symporter activity(GO:0008508) |
0.2 | 2.9 | GO:0005314 | high-affinity glutamate transmembrane transporter activity(GO:0005314) |
0.2 | 1.5 | GO:0052650 | NADP-retinol dehydrogenase activity(GO:0052650) |
0.2 | 1.5 | GO:0038132 | neuregulin binding(GO:0038132) |
0.2 | 2.7 | GO:0097109 | neuroligin family protein binding(GO:0097109) |
0.2 | 0.6 | GO:0030977 | taurine binding(GO:0030977) |
0.2 | 1.6 | GO:0004630 | phospholipase D activity(GO:0004630) |
0.2 | 4.2 | GO:0047555 | 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555) |
0.2 | 2.4 | GO:0001161 | intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) |
0.1 | 0.6 | GO:0004582 | dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582) |
0.1 | 1.4 | GO:0035251 | UDP-glucosyltransferase activity(GO:0035251) |
0.1 | 1.5 | GO:0015217 | ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217) |
0.1 | 0.5 | GO:1904288 | BAT3 complex binding(GO:1904288) |
0.1 | 2.5 | GO:0008137 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
0.1 | 2.0 | GO:0045295 | gamma-catenin binding(GO:0045295) |
0.1 | 9.6 | GO:0005179 | hormone activity(GO:0005179) |
0.1 | 0.3 | GO:0004517 | nitric-oxide synthase activity(GO:0004517) |
0.1 | 2.6 | GO:0016831 | carboxy-lyase activity(GO:0016831) |
0.0 | 0.3 | GO:0022851 | GABA-gated chloride ion channel activity(GO:0022851) |
0.0 | 3.0 | GO:0030971 | receptor tyrosine kinase binding(GO:0030971) |
0.0 | 0.5 | GO:0017154 | semaphorin receptor activity(GO:0017154) |
0.0 | 0.1 | GO:0004947 | bradykinin receptor activity(GO:0004947) |
0.0 | 0.1 | GO:0098918 | structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973) |
0.0 | 0.6 | GO:0016671 | oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671) |
0.0 | 0.3 | GO:0001594 | trace-amine receptor activity(GO:0001594) |
0.0 | 0.1 | GO:0034714 | type III transforming growth factor beta receptor binding(GO:0034714) |
0.0 | 0.4 | GO:0070700 | BMP receptor binding(GO:0070700) |
0.0 | 0.1 | GO:0030280 | structural constituent of epidermis(GO:0030280) |
0.0 | 0.4 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
0.0 | 0.3 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
0.0 | 0.3 | GO:0052813 | phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813) |
0.0 | 0.1 | GO:0031697 | beta-1 adrenergic receptor binding(GO:0031697) type II activin receptor binding(GO:0070699) |
0.0 | 0.5 | GO:0004115 | 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) |
0.0 | 1.6 | GO:0048306 | calcium-dependent protein binding(GO:0048306) |
0.0 | 2.7 | GO:0004386 | helicase activity(GO:0004386) |
0.0 | 0.8 | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547) |
0.0 | 0.2 | GO:0008271 | secondary active sulfate transmembrane transporter activity(GO:0008271) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 1.5 | PID ERBB NETWORK PATHWAY | ErbB receptor signaling network |
0.1 | 4.8 | PID AR TF PATHWAY | Regulation of Androgen receptor activity |
0.1 | 4.0 | PID FOXO PATHWAY | FoxO family signaling |
0.1 | 1.1 | PID ANTHRAX PATHWAY | Cellular roles of Anthrax toxin |
0.0 | 1.6 | PID FRA PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
0.0 | 2.0 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
0.0 | 1.6 | PID UPA UPAR PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
0.0 | 1.4 | PID IFNG PATHWAY | IFN-gamma pathway |
0.0 | 1.5 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
0.0 | 1.4 | PID NFAT TFPATHWAY | Calcineurin-regulated NFAT-dependent transcription in lymphocytes |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 1.6 | REACTOME RECYCLING OF BILE ACIDS AND SALTS | Genes involved in Recycling of bile acids and salts |
0.2 | 3.1 | REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION | Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation |
0.1 | 2.6 | REACTOME TRYPTOPHAN CATABOLISM | Genes involved in Tryptophan catabolism |
0.1 | 1.4 | REACTOME CALNEXIN CALRETICULIN CYCLE | Genes involved in Calnexin/calreticulin cycle |
0.1 | 4.0 | REACTOME CGMP EFFECTS | Genes involved in cGMP effects |
0.1 | 2.1 | REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS | Genes involved in Regulation of gene expression in beta cells |
0.1 | 1.5 | REACTOME SHC1 EVENTS IN ERBB4 SIGNALING | Genes involved in SHC1 events in ERBB4 signaling |
0.0 | 0.3 | REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE | Genes involved in Nitric oxide stimulates guanylate cyclase |
0.0 | 0.6 | REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS | Genes involved in Synthesis of substrates in N-glycan biosythesis |
0.0 | 0.5 | REACTOME TIE2 SIGNALING | Genes involved in Tie2 Signaling |
0.0 | 0.5 | REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION | Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion |
0.0 | 0.8 | REACTOME LIGAND GATED ION CHANNEL TRANSPORT | Genes involved in Ligand-gated ion channel transport |
0.0 | 1.0 | REACTOME GLUCONEOGENESIS | Genes involved in Gluconeogenesis |
0.0 | 0.5 | REACTOME DARPP 32 EVENTS | Genes involved in DARPP-32 events |
0.0 | 2.1 | REACTOME PPARA ACTIVATES GENE EXPRESSION | Genes involved in PPARA Activates Gene Expression |
0.0 | 1.0 | REACTOME RESPIRATORY ELECTRON TRANSPORT | Genes involved in Respiratory electron transport |
0.0 | 3.1 | REACTOME G ALPHA I SIGNALLING EVENTS | Genes involved in G alpha (i) signalling events |
0.0 | 0.2 | REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |