avrg: GSE58827: Dynamics of the Mouse Liver
Gene Symbol | Gene ID | Gene Info |
---|---|---|
Tbx1
|
ENSMUSG00000009097.9 | T-box 1 |
Eomes
|
ENSMUSG00000032446.8 | eomesodermin |
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Tbx1 | mm10_v2_chr16_-_18586959_18586970 | 0.32 | 5.9e-02 | Click! |
Eomes | mm10_v2_chr9_+_118478851_118478866 | 0.28 | 1.0e-01 | Click! |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.6 | 4.8 | GO:0051714 | regulation of cytolysis in other organism(GO:0051710) positive regulation of cytolysis in other organism(GO:0051714) |
0.4 | 1.3 | GO:0061537 | glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537) |
0.4 | 1.1 | GO:0001928 | regulation of exocyst assembly(GO:0001928) |
0.3 | 1.1 | GO:0035524 | proline transmembrane transport(GO:0035524) |
0.3 | 0.8 | GO:0090526 | regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526) |
0.3 | 2.3 | GO:0010587 | miRNA catabolic process(GO:0010587) |
0.2 | 0.7 | GO:0002355 | detection of tumor cell(GO:0002355) |
0.2 | 2.4 | GO:0048859 | formation of anatomical boundary(GO:0048859) |
0.2 | 1.9 | GO:0090527 | actin filament reorganization(GO:0090527) |
0.2 | 0.5 | GO:0045360 | regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362) |
0.2 | 0.8 | GO:0035616 | histone H2B conserved C-terminal lysine deubiquitination(GO:0035616) |
0.2 | 1.9 | GO:0010944 | negative regulation of transcription by competitive promoter binding(GO:0010944) |
0.2 | 0.5 | GO:0051866 | general adaptation syndrome(GO:0051866) |
0.2 | 0.6 | GO:0014012 | peripheral nervous system axon regeneration(GO:0014012) bud outgrowth involved in lung branching(GO:0060447) |
0.1 | 0.4 | GO:0060557 | positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559) |
0.1 | 0.4 | GO:0043435 | response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376) |
0.1 | 0.8 | GO:0050916 | sensory perception of sweet taste(GO:0050916) |
0.1 | 0.4 | GO:1902303 | negative regulation of potassium ion export(GO:1902303) |
0.1 | 0.4 | GO:1900108 | negative regulation of nodal signaling pathway(GO:1900108) |
0.1 | 0.9 | GO:0036005 | response to macrophage colony-stimulating factor(GO:0036005) cellular response to macrophage colony-stimulating factor stimulus(GO:0036006) |
0.1 | 0.4 | GO:0070889 | platelet alpha granule organization(GO:0070889) |
0.1 | 0.3 | GO:1902896 | terminal web assembly(GO:1902896) |
0.1 | 0.6 | GO:0060708 | spongiotrophoblast differentiation(GO:0060708) |
0.1 | 0.3 | GO:0035521 | monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522) |
0.1 | 0.2 | GO:0006597 | spermine biosynthetic process(GO:0006597) |
0.1 | 0.2 | GO:0045226 | hyaluranon cable assembly(GO:0036118) extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106) |
0.1 | 0.2 | GO:0017055 | negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055) |
0.1 | 0.3 | GO:0097527 | necroptotic signaling pathway(GO:0097527) |
0.1 | 0.4 | GO:0045213 | neurotransmitter receptor metabolic process(GO:0045213) |
0.1 | 2.6 | GO:0000186 | activation of MAPKK activity(GO:0000186) |
0.1 | 0.8 | GO:0048012 | hepatocyte growth factor receptor signaling pathway(GO:0048012) |
0.1 | 0.4 | GO:0048539 | bone marrow development(GO:0048539) |
0.1 | 0.3 | GO:0051697 | protein delipidation(GO:0051697) |
0.1 | 0.4 | GO:0072321 | chaperone-mediated protein transport(GO:0072321) |
0.0 | 0.3 | GO:0045200 | establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200) |
0.0 | 0.1 | GO:2001160 | regulation of histone H3-K79 methylation(GO:2001160) |
0.0 | 0.2 | GO:0060830 | ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830) |
0.0 | 0.8 | GO:0050774 | negative regulation of dendrite morphogenesis(GO:0050774) |
0.0 | 2.7 | GO:0007585 | respiratory gaseous exchange(GO:0007585) |
0.0 | 0.4 | GO:0021546 | rhombomere development(GO:0021546) |
0.0 | 2.1 | GO:0035411 | catenin import into nucleus(GO:0035411) |
0.0 | 0.4 | GO:0071493 | cellular response to UV-B(GO:0071493) |
0.0 | 0.3 | GO:1903849 | regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849) |
0.0 | 0.3 | GO:0060455 | negative regulation of gastric acid secretion(GO:0060455) |
0.0 | 0.3 | GO:0021780 | oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780) |
0.0 | 0.2 | GO:2000210 | positive regulation of anoikis(GO:2000210) |
0.0 | 0.1 | GO:0044027 | hypermethylation of CpG island(GO:0044027) |
0.0 | 0.3 | GO:0071285 | cellular response to lithium ion(GO:0071285) |
0.0 | 0.6 | GO:2000001 | regulation of DNA damage checkpoint(GO:2000001) |
0.0 | 0.9 | GO:0018345 | protein palmitoylation(GO:0018345) |
0.0 | 0.1 | GO:0098917 | retrograde trans-synaptic signaling(GO:0098917) |
0.0 | 0.2 | GO:1901837 | negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837) |
0.0 | 1.1 | GO:0030225 | macrophage differentiation(GO:0030225) |
0.0 | 0.3 | GO:0099628 | receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628) |
0.0 | 0.1 | GO:0010643 | cell communication by chemical coupling(GO:0010643) |
0.0 | 0.4 | GO:0060059 | embryonic retina morphogenesis in camera-type eye(GO:0060059) |
0.0 | 0.6 | GO:1903861 | positive regulation of dendrite extension(GO:1903861) |
0.0 | 0.2 | GO:0035562 | negative regulation of chromatin binding(GO:0035562) snRNA modification(GO:0040031) |
0.0 | 0.2 | GO:0036506 | maintenance of unfolded protein(GO:0036506) tail-anchored membrane protein insertion into ER membrane(GO:0071816) maintenance of unfolded protein involved in ERAD pathway(GO:1904378) |
0.0 | 0.3 | GO:1901386 | negative regulation of voltage-gated calcium channel activity(GO:1901386) |
0.0 | 0.6 | GO:0048791 | calcium ion-regulated exocytosis of neurotransmitter(GO:0048791) |
0.0 | 0.4 | GO:0034389 | lipid particle organization(GO:0034389) |
0.0 | 2.9 | GO:0045667 | regulation of osteoblast differentiation(GO:0045667) |
0.0 | 0.1 | GO:0050915 | sensory perception of sour taste(GO:0050915) |
0.0 | 0.2 | GO:0060159 | G-protein coupled acetylcholine receptor signaling pathway(GO:0007213) regulation of dopamine receptor signaling pathway(GO:0060159) |
0.0 | 0.1 | GO:0017196 | N-terminal peptidyl-methionine acetylation(GO:0017196) |
0.0 | 0.2 | GO:0001778 | plasma membrane repair(GO:0001778) |
0.0 | 0.3 | GO:0016578 | histone deubiquitination(GO:0016578) |
0.0 | 0.8 | GO:1900047 | negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047) |
0.0 | 0.5 | GO:0019236 | response to pheromone(GO:0019236) |
0.0 | 0.7 | GO:0001919 | regulation of receptor recycling(GO:0001919) |
0.0 | 0.1 | GO:0002158 | osteoclast proliferation(GO:0002158) |
0.0 | 0.2 | GO:0030953 | astral microtubule organization(GO:0030953) |
0.0 | 0.7 | GO:0043666 | regulation of phosphoprotein phosphatase activity(GO:0043666) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 2.6 | GO:0097208 | alveolar lamellar body(GO:0097208) |
0.1 | 0.4 | GO:0070557 | PCNA-p21 complex(GO:0070557) |
0.1 | 0.6 | GO:1990769 | proximal neuron projection(GO:1990769) |
0.1 | 0.4 | GO:1902937 | inward rectifier potassium channel complex(GO:1902937) |
0.1 | 0.6 | GO:0032299 | ribonuclease H2 complex(GO:0032299) |
0.1 | 0.8 | GO:1990316 | ATG1/ULK1 kinase complex(GO:1990316) |
0.1 | 0.3 | GO:0099524 | region of cytosol(GO:0099522) postsynaptic cytosol(GO:0099524) |
0.1 | 0.2 | GO:0097135 | cyclin E2-CDK2 complex(GO:0097135) |
0.1 | 1.0 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
0.0 | 0.7 | GO:0043083 | synaptic cleft(GO:0043083) |
0.0 | 0.3 | GO:1990357 | terminal web(GO:1990357) |
0.0 | 2.3 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
0.0 | 0.2 | GO:0071818 | BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379) |
0.0 | 0.2 | GO:0005826 | actomyosin contractile ring(GO:0005826) |
0.0 | 1.9 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
0.0 | 0.8 | GO:0032154 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
0.0 | 1.2 | GO:0009925 | basal plasma membrane(GO:0009925) |
0.0 | 2.3 | GO:0072562 | blood microparticle(GO:0072562) |
0.0 | 0.1 | GO:0016593 | Cdc73/Paf1 complex(GO:0016593) |
0.0 | 0.1 | GO:0031415 | NatA complex(GO:0031415) |
0.0 | 0.4 | GO:0030131 | clathrin adaptor complex(GO:0030131) |
0.0 | 0.4 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
0.0 | 1.9 | GO:0005884 | actin filament(GO:0005884) |
0.0 | 0.8 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
0.0 | 0.4 | GO:0030673 | axolemma(GO:0030673) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.0 | 4.8 | GO:0008745 | N-acetylmuramoyl-L-alanine amidase activity(GO:0008745) peptidoglycan receptor activity(GO:0016019) |
0.6 | 1.9 | GO:0071820 | N-box binding(GO:0071820) |
0.2 | 1.9 | GO:0008889 | glycerophosphodiester phosphodiesterase activity(GO:0008889) |
0.2 | 2.3 | GO:0002151 | G-quadruplex RNA binding(GO:0002151) |
0.1 | 0.8 | GO:0070728 | leucine binding(GO:0070728) |
0.1 | 1.3 | GO:0015187 | glycine transmembrane transporter activity(GO:0015187) |
0.1 | 0.9 | GO:0004117 | calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101) |
0.1 | 0.4 | GO:0019912 | cyclin-dependent protein kinase activating kinase activity(GO:0019912) |
0.1 | 0.4 | GO:0005176 | ErbB-2 class receptor binding(GO:0005176) |
0.1 | 0.4 | GO:0038100 | nodal binding(GO:0038100) |
0.1 | 1.1 | GO:0015193 | L-proline transmembrane transporter activity(GO:0015193) |
0.1 | 0.7 | GO:0004971 | AMPA glutamate receptor activity(GO:0004971) |
0.1 | 0.6 | GO:0004523 | RNA-DNA hybrid ribonuclease activity(GO:0004523) |
0.1 | 2.3 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
0.1 | 0.6 | GO:0045545 | syndecan binding(GO:0045545) |
0.1 | 0.4 | GO:0000155 | phosphorelay sensor kinase activity(GO:0000155) voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282) |
0.1 | 0.2 | GO:0002153 | steroid receptor RNA activator RNA binding(GO:0002153) |
0.1 | 0.2 | GO:0050501 | hyaluronan synthase activity(GO:0050501) |
0.0 | 1.1 | GO:0030275 | LRR domain binding(GO:0030275) |
0.0 | 0.4 | GO:0043208 | glycosphingolipid binding(GO:0043208) |
0.0 | 0.2 | GO:0004045 | aminoacyl-tRNA hydrolase activity(GO:0004045) |
0.0 | 2.4 | GO:0005160 | transforming growth factor beta receptor binding(GO:0005160) |
0.0 | 0.3 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
0.0 | 0.2 | GO:0019808 | polyamine binding(GO:0019808) |
0.0 | 0.4 | GO:0051371 | muscle alpha-actinin binding(GO:0051371) |
0.0 | 0.9 | GO:0019707 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707) |
0.0 | 0.9 | GO:0035259 | glucocorticoid receptor binding(GO:0035259) |
0.0 | 0.3 | GO:0045236 | CXCR chemokine receptor binding(GO:0045236) |
0.0 | 0.5 | GO:0005123 | death receptor binding(GO:0005123) |
0.0 | 0.5 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
0.0 | 0.2 | GO:0031404 | chloride ion binding(GO:0031404) |
0.0 | 0.5 | GO:0008009 | chemokine activity(GO:0008009) |
0.0 | 0.9 | GO:0008307 | structural constituent of muscle(GO:0008307) |
0.0 | 1.1 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
0.0 | 0.1 | GO:0003886 | DNA (cytosine-5-)-methyltransferase activity(GO:0003886) |
0.0 | 0.1 | GO:0086075 | gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075) |
0.0 | 0.6 | GO:0001784 | phosphotyrosine binding(GO:0001784) |
0.0 | 0.2 | GO:0003688 | DNA replication origin binding(GO:0003688) |
0.0 | 2.6 | GO:0017124 | SH3 domain binding(GO:0017124) |
0.0 | 0.3 | GO:0032794 | GTPase activating protein binding(GO:0032794) |
0.0 | 0.1 | GO:0004861 | cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861) |
0.0 | 0.2 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
0.0 | 0.6 | GO:0001786 | phosphatidylserine binding(GO:0001786) |
0.0 | 0.5 | GO:0004864 | protein phosphatase inhibitor activity(GO:0004864) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 1.1 | PID TCR JNK PATHWAY | JNK signaling in the CD4+ TCR pathway |
0.1 | 3.1 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
0.0 | 0.4 | SA G2 AND M PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
0.0 | 0.4 | ST INTERFERON GAMMA PATHWAY | Interferon gamma pathway. |
0.0 | 3.9 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
0.0 | 0.6 | PID INTEGRIN A9B1 PATHWAY | Alpha9 beta1 integrin signaling events |
0.0 | 1.9 | PID HIF1 TFPATHWAY | HIF-1-alpha transcription factor network |
0.0 | 0.4 | ST GA12 PATHWAY | G alpha 12 Pathway |
0.0 | 1.4 | PID FGF PATHWAY | FGF signaling pathway |
0.0 | 0.6 | PID EPO PATHWAY | EPO signaling pathway |
0.0 | 0.8 | PID RHOA PATHWAY | RhoA signaling pathway |
0.0 | 1.1 | PID MET PATHWAY | Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) |
0.0 | 0.2 | SA REG CASCADE OF CYCLIN EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
0.0 | 0.5 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
0.0 | 0.3 | PID EPHRINB REV PATHWAY | Ephrin B reverse signaling |
0.0 | 0.4 | PID GLYPICAN 1PATHWAY | Glypican 1 network |
0.0 | 0.3 | PID P38 MKK3 6PATHWAY | p38 MAPK signaling pathway |
0.0 | 3.4 | NABA SECRETED FACTORS | Genes encoding secreted soluble factors |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 2.9 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
0.1 | 1.0 | REACTOME REGULATION OF IFNG SIGNALING | Genes involved in Regulation of IFNG signaling |
0.0 | 1.1 | REACTOME GENERATION OF SECOND MESSENGER MOLECULES | Genes involved in Generation of second messenger molecules |
0.0 | 1.4 | REACTOME INTERFERON GAMMA SIGNALING | Genes involved in Interferon gamma signaling |
0.0 | 1.8 | REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION | Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression |
0.0 | 0.5 | REACTOME CS DS DEGRADATION | Genes involved in CS/DS degradation |
0.0 | 1.2 | REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS | Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers |
0.0 | 0.9 | REACTOME CGMP EFFECTS | Genes involved in cGMP effects |
0.0 | 0.4 | REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL | Genes involved in AKT phosphorylates targets in the cytosol |
0.0 | 0.4 | REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION | Genes involved in Unblocking of NMDA receptor, glutamate binding and activation |
0.0 | 0.4 | REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING | Genes involved in Downregulation of ERBB2:ERBB3 signaling |
0.0 | 0.7 | REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
0.0 | 0.4 | REACTOME SIGNALING BY NODAL | Genes involved in Signaling by NODAL |
0.0 | 0.2 | REACTOME HYALURONAN METABOLISM | Genes involved in Hyaluronan metabolism |
0.0 | 0.3 | REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS | Genes involved in Na+/Cl- dependent neurotransmitter transporters |
0.0 | 0.3 | REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS | Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
0.0 | 0.5 | REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |