Project

avrg: GSE58827: Dynamics of the Mouse Liver

Navigation
Downloads

Results for ACAGUAC

Z-value: 0.67

Motif logo

miRNA associated with seed ACAGUAC

NamemiRBASE accession
MIMAT0000133

Activity profile of ACAGUAC motif

Sorted Z-values of ACAGUAC motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ACAGUAC

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0071350 interleukin-15-mediated signaling pathway(GO:0035723) activation of meiosis involved in egg activation(GO:0060466) cellular response to interleukin-15(GO:0071350) response to fluoride(GO:1902617)
0.3 0.9 GO:1905223 epicardium morphogenesis(GO:1905223)
0.3 0.8 GO:1904339 negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.2 1.1 GO:1904382 protein deglycosylation involved in glycoprotein catabolic process(GO:0035977) protein demannosylation(GO:0036507) protein alpha-1,2-demannosylation(GO:0036508) glycoprotein ERAD pathway(GO:0097466) mannose trimming involved in glycoprotein ERAD pathway(GO:1904382)
0.2 0.8 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.2 0.6 GO:2000979 hepatocyte cell migration(GO:0002194) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.2 0.4 GO:0048294 negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.2 0.8 GO:2000721 positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.2 0.6 GO:0061300 cerebellum vasculature development(GO:0061300)
0.2 0.6 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.2 0.9 GO:0032237 activation of store-operated calcium channel activity(GO:0032237)
0.2 0.5 GO:0035622 intrahepatic bile duct development(GO:0035622) renal vesicle induction(GO:0072034)
0.2 0.5 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.2 0.7 GO:0097393 post-embryonic appendage morphogenesis(GO:0035120) post-embryonic limb morphogenesis(GO:0035127) post-embryonic forelimb morphogenesis(GO:0035128) telomeric repeat-containing RNA transcription(GO:0097393) telomeric repeat-containing RNA transcription from RNA pol II promoter(GO:0097394) regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901580) negative regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901581) positive regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901582)
0.1 0.6 GO:0014734 skeletal muscle hypertrophy(GO:0014734)
0.1 0.4 GO:0031064 negative regulation of histone deacetylation(GO:0031064)
0.1 0.4 GO:0019858 cytosine metabolic process(GO:0019858)
0.1 0.4 GO:0035441 vestibulocochlear nerve structural organization(GO:0021649) cell migration involved in vasculogenesis(GO:0035441) neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190) ganglion morphogenesis(GO:0061552) dorsal root ganglion morphogenesis(GO:1904835)
0.1 0.2 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
0.1 0.1 GO:1904753 negative regulation of vascular associated smooth muscle cell migration(GO:1904753)
0.1 0.7 GO:0071955 recycling endosome to Golgi transport(GO:0071955)
0.1 0.3 GO:0021934 hindbrain tangential cell migration(GO:0021934)
0.1 0.3 GO:0071873 response to norepinephrine(GO:0071873)
0.1 0.5 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.1 0.4 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340)
0.1 0.4 GO:0009957 epidermal cell fate specification(GO:0009957)
0.1 0.6 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.1 0.4 GO:0015801 aromatic amino acid transport(GO:0015801) tryptophan transport(GO:0015827)
0.1 0.4 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.1 0.6 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.1 0.3 GO:0050975 sensory perception of touch(GO:0050975)
0.1 0.5 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.1 0.3 GO:0097401 synaptic vesicle lumen acidification(GO:0097401)
0.1 0.5 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.1 0.2 GO:0060849 regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.1 0.2 GO:2000384 regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.1 0.2 GO:0010814 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.1 0.6 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.1 0.2 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.1 0.3 GO:0003415 chondrocyte hypertrophy(GO:0003415)
0.1 0.4 GO:0034421 post-translational protein acetylation(GO:0034421)
0.1 0.4 GO:1901908 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.1 0.2 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.1 0.5 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.1 0.4 GO:0098961 dendritic transport of ribonucleoprotein complex(GO:0098961) dendritic transport of messenger ribonucleoprotein complex(GO:0098963) anterograde dendritic transport of messenger ribonucleoprotein complex(GO:0098964)
0.1 0.2 GO:1903279 regulation of calcium:sodium antiporter activity(GO:1903279)
0.1 0.6 GO:0048102 autophagic cell death(GO:0048102)
0.1 0.7 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.1 0.2 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.1 0.7 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.1 0.8 GO:0048733 sebaceous gland development(GO:0048733)
0.1 0.1 GO:0021553 olfactory nerve development(GO:0021553)
0.1 0.2 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 0.7 GO:0014029 neural crest formation(GO:0014029)
0.1 1.0 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.1 0.3 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.1 0.2 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.1 0.6 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1 0.8 GO:0048199 vesicle targeting, to, from or within Golgi(GO:0048199)
0.1 0.2 GO:1903722 regulation of centriole elongation(GO:1903722)
0.1 1.2 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
0.1 0.4 GO:0042636 negative regulation of hair cycle(GO:0042636)
0.1 0.4 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1 0.2 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 0.2 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.1 0.3 GO:0042256 mature ribosome assembly(GO:0042256)
0.1 0.3 GO:1904180 negative regulation of membrane depolarization(GO:1904180)
0.0 0.1 GO:1905053 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
0.0 0.6 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.2 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.1 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
0.0 0.0 GO:0070384 Harderian gland development(GO:0070384)
0.0 0.4 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.0 0.4 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.3 GO:0072697 protein localization to cell cortex(GO:0072697)
0.0 0.2 GO:0006538 glutamate catabolic process(GO:0006538)
0.0 0.1 GO:0009826 unidimensional cell growth(GO:0009826)
0.0 0.1 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.0 0.1 GO:0035166 post-embryonic hemopoiesis(GO:0035166)
0.0 0.1 GO:0061113 pancreas morphogenesis(GO:0061113)
0.0 0.1 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.0 0.2 GO:1902608 negative regulation of inositol phosphate biosynthetic process(GO:0010920) regulation of large conductance calcium-activated potassium channel activity(GO:1902606) positive regulation of large conductance calcium-activated potassium channel activity(GO:1902608) regulation of testosterone biosynthetic process(GO:2000224)
0.0 0.2 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.0 0.2 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.0 0.5 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.8 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.0 0.5 GO:0045623 negative regulation of CD4-positive, alpha-beta T cell differentiation(GO:0043371) negative regulation of T-helper cell differentiation(GO:0045623)
0.0 0.7 GO:0007289 spermatid nucleus differentiation(GO:0007289)
0.0 0.3 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.5 GO:1990403 embryonic brain development(GO:1990403)
0.0 0.2 GO:1900170 prolactin signaling pathway(GO:0038161) negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.0 0.2 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.2 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.0 0.1 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.0 0.3 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.2 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.2 GO:0072675 osteoclast fusion(GO:0072675)
0.0 0.3 GO:0036315 cellular response to sterol(GO:0036315)
0.0 0.4 GO:0090209 negative regulation of triglyceride metabolic process(GO:0090209)
0.0 0.2 GO:1902513 regulation of organelle transport along microtubule(GO:1902513)
0.0 0.2 GO:0001955 blood vessel maturation(GO:0001955)
0.0 0.3 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.0 0.5 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.3 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.7 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 0.3 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 0.1 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344) formin-nucleated actin cable assembly(GO:0070649)
0.0 0.4 GO:0010225 response to UV-C(GO:0010225)
0.0 0.2 GO:0002756 MyD88-independent toll-like receptor signaling pathway(GO:0002756)
0.0 0.1 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.0 0.6 GO:0032288 myelin assembly(GO:0032288)
0.0 0.3 GO:0090051 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) negative regulation of cell migration involved in sprouting angiogenesis(GO:0090051)
0.0 0.2 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.0 0.2 GO:0060613 fat pad development(GO:0060613)
0.0 0.2 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.0 0.2 GO:0035280 miRNA loading onto RISC involved in gene silencing by miRNA(GO:0035280)
0.0 0.3 GO:0034453 microtubule anchoring(GO:0034453)
0.0 0.1 GO:0015888 thiamine transport(GO:0015888)
0.0 0.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.1 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.0 0.2 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.2 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.0 0.1 GO:0099527 postsynapse to nucleus signaling pathway(GO:0099527)
0.0 0.1 GO:0000022 mitotic spindle elongation(GO:0000022) mitotic spindle midzone assembly(GO:0051256)
0.0 0.1 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.1 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.0 0.1 GO:0022417 protein maturation by protein folding(GO:0022417)
0.0 0.7 GO:0061512 protein localization to cilium(GO:0061512)
0.0 0.0 GO:0045643 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.0 0.1 GO:0030578 PML body organization(GO:0030578) positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
0.0 0.4 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.0 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0 0.6 GO:2001222 regulation of neuron migration(GO:2001222)
0.0 0.0 GO:2000820 negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)
0.0 0.1 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.0 0.1 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.2 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.1 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0 0.1 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.0 GO:1900477 negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter(GO:1900477)
0.0 0.0 GO:0019085 early viral transcription(GO:0019085)
0.0 0.1 GO:0044336 canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.0 0.1 GO:1903849 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:1990421 subtelomeric heterochromatin(GO:1990421) nuclear subtelomeric heterochromatin(GO:1990707)
0.1 0.5 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.1 0.5 GO:1990812 growth cone filopodium(GO:1990812)
0.1 0.5 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 0.8 GO:1990909 Wnt signalosome(GO:1990909)
0.1 0.2 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.1 0.3 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 0.4 GO:0097443 sorting endosome(GO:0097443)
0.1 0.6 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.1 0.4 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 0.8 GO:0030126 COPI vesicle coat(GO:0030126)
0.1 0.5 GO:0090576 RNA polymerase III transcription factor complex(GO:0090576)
0.0 0.4 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.6 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 1.0 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.3 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.3 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.4 GO:0016011 dystroglycan complex(GO:0016011)
0.0 0.4 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.8 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.4 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.1 GO:0071953 elastic fiber(GO:0071953)
0.0 0.3 GO:0043219 lateral loop(GO:0043219)
0.0 0.1 GO:0032437 cuticular plate(GO:0032437)
0.0 0.4 GO:0045180 basal cortex(GO:0045180)
0.0 0.6 GO:0000145 exocyst(GO:0000145)
0.0 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.2 GO:0089701 U2AF(GO:0089701)
0.0 1.2 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.4 GO:0030128 clathrin coat of endocytic vesicle(GO:0030128)
0.0 0.2 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 1.3 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.1 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.6 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.2 GO:0070578 RISC-loading complex(GO:0070578)
0.0 1.5 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.3 GO:0042581 specific granule(GO:0042581)
0.0 0.5 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.2 GO:0005916 fascia adherens(GO:0005916)
0.0 0.2 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.1 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.3 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.2 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.1 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.1 GO:1990037 Lewy body core(GO:1990037)
0.0 0.1 GO:0001651 dense fibrillar component(GO:0001651)
0.0 0.6 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.2 GO:0032156 septin cytoskeleton(GO:0032156)
0.0 0.2 GO:0090543 Flemming body(GO:0090543)
0.0 0.5 GO:0016592 mediator complex(GO:0016592)
0.0 0.5 GO:0035869 ciliary transition zone(GO:0035869)
0.0 0.0 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.3 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.3 GO:0042588 zymogen granule(GO:0042588)
0.0 0.1 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.2 GO:0035267 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.2 GO:0000242 pericentriolar material(GO:0000242)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.1 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.2 1.0 GO:0004594 pantothenate kinase activity(GO:0004594)
0.2 0.5 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.2 0.8 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.2 0.6 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 0.4 GO:0005119 smoothened binding(GO:0005119) hedgehog receptor activity(GO:0008158)
0.1 1.1 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 0.4 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.1 1.1 GO:0071253 connexin binding(GO:0071253)
0.1 0.4 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.1 0.9 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.1 0.7 GO:0015616 DNA translocase activity(GO:0015616)
0.1 0.4 GO:0035276 ethanol binding(GO:0035276)
0.1 0.5 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 0.4 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.1 0.4 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.1 1.4 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.1 0.4 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.1 0.2 GO:0008520 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.1 0.3 GO:0051425 PTB domain binding(GO:0051425)
0.1 0.6 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.1 0.2 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.1 0.3 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.1 0.6 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 0.3 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 0.4 GO:0033592 RNA strand annealing activity(GO:0033592)
0.1 0.2 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.1 0.3 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.3 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.2 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.0 0.4 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.6 GO:0001727 lipid kinase activity(GO:0001727)
0.0 0.4 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.6 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.2 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.9 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.6 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.2 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.4 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.2 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.0 0.2 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.4 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.7 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.4 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.2 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.2 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.1 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.0 0.1 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.2 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.4 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.5 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.1 GO:0097100 supercoiled DNA binding(GO:0097100)
0.0 0.2 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.4 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.5 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.4 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.4 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.5 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.2 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.4 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.3 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.7 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.4 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.2 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.2 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.1 GO:0034452 dynactin binding(GO:0034452)
0.0 0.1 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.5 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 0.2 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.2 GO:0030955 potassium ion binding(GO:0030955)
0.0 0.0 GO:0070324 thyroid hormone binding(GO:0070324)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.9 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.2 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 0.4 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 1.3 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 1.3 PID AURORA A PATHWAY Aurora A signaling
0.0 1.2 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.0 PID EPO PATHWAY EPO signaling pathway
0.0 0.6 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.1 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.3 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 0.6 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.5 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.9 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.3 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.3 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.6 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.1 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.6 PID INSULIN PATHWAY Insulin Pathway
0.0 0.5 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.2 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 0.9 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 1.0 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.7 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 0.9 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.8 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.3 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.6 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.5 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.6 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.1 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 0.5 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.1 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 1.9 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.3 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.6 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.4 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.2 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.1 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.1 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.0 0.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.5 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell