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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Stat2

Z-value: 1.71

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Transcription factors associated with Stat2

Gene Symbol Gene ID Gene Info
Stat2
ENSMUSG00000040033.9 signal transducer and activator of transcription 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Stat2mm10_v2_chr10_+_128270546_1282705770.711.0e-06Click!

Activity profile of Stat2 motif

Sorted Z-values of Stat2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr15_+_77729091 12.27 ENSMUST00000109775.2
Apol9b
apolipoprotein L 9b
chr6_+_41521782 9.31 ENSMUST00000070380.4
Prss2
protease, serine, 2
chr15_-_77411034 8.03 ENSMUST00000089452.5
ENSMUST00000081776.3
Apol9a
apolipoprotein L 9a
chr7_-_141010759 7.50 ENSMUST00000026565.6
Ifitm3
interferon induced transmembrane protein 3
chr1_+_130826762 6.94 ENSMUST00000133792.1
Pigr
polymeric immunoglobulin receptor
chr1_+_130826676 6.61 ENSMUST00000027675.7
Pigr
polymeric immunoglobulin receptor
chr1_+_167618246 6.59 ENSMUST00000111380.1
Rxrg
retinoid X receptor gamma
chr10_+_40629987 6.31 ENSMUST00000019977.7
Ddo
D-aspartate oxidase
chr6_+_41392356 6.24 ENSMUST00000049079.7
Gm5771
predicted gene 5771
chr4_-_42756543 6.04 ENSMUST00000102957.3
Ccl19
chemokine (C-C motif) ligand 19
chr16_+_26581704 5.76 ENSMUST00000096129.2
ENSMUST00000166294.2
ENSMUST00000174202.1
ENSMUST00000023156.6
Il1rap
interleukin 1 receptor accessory protein
chr19_-_11050500 5.75 ENSMUST00000099676.4
AW112010
expressed sequence AW112010
chr4_+_42629719 5.71 ENSMUST00000166898.2
Gm2564
predicted gene 2564
chr2_-_173218879 5.57 ENSMUST00000109116.2
ENSMUST00000029018.7
Zbp1
Z-DNA binding protein 1
chr6_+_41458923 5.49 ENSMUST00000031910.7
Prss1
protease, serine, 1 (trypsin 1)
chr19_+_34583528 5.29 ENSMUST00000102825.3
Ifit3
interferon-induced protein with tetratricopeptide repeats 3
chr19_+_34607927 5.21 ENSMUST00000076249.5
I830012O16Rik
RIKEN cDNA I830012O16 gene
chr8_-_45333189 5.05 ENSMUST00000095328.4
Cyp4v3
cytochrome P450, family 4, subfamily v, polypeptide 3
chr12_+_104406704 4.93 ENSMUST00000021506.5
Serpina3n
serine (or cysteine) peptidase inhibitor, clade A, member 3N
chr19_+_34640871 4.71 ENSMUST00000102824.3
Ifit1
interferon-induced protein with tetratricopeptide repeats 1
chr18_+_60212080 4.69 ENSMUST00000031549.5
Gm4951
predicted gene 4951
chr4_+_42114817 4.47 ENSMUST00000098123.3
Gm13304
predicted gene 13304
chr16_+_43363855 4.31 ENSMUST00000156367.1
Zbtb20
zinc finger and BTB domain containing 20
chr4_+_41903610 4.29 ENSMUST00000098128.3
Gm21541
predicted gene, 21541
chr14_+_41105359 4.15 ENSMUST00000047286.6
Mat1a
methionine adenosyltransferase I, alpha
chr19_-_46148369 4.05 ENSMUST00000026259.9
Pitx3
paired-like homeodomain transcription factor 3
chr8_+_107150621 4.02 ENSMUST00000034400.3
Cyb5b
cytochrome b5 type B
chr4_-_42773993 3.98 ENSMUST00000095114.4
Ccl21a
chemokine (C-C motif) ligand 21A (serine)
chr10_+_87860030 3.91 ENSMUST00000062862.6
Igf1
insulin-like growth factor 1
chr4_+_42255767 3.87 ENSMUST00000178864.1
Ccl21b
chemokine (C-C motif) ligand 21B (leucine)
chr6_-_23839137 3.77 ENSMUST00000166458.2
ENSMUST00000142913.2
ENSMUST00000115357.1
ENSMUST00000069074.7
ENSMUST00000115361.2
ENSMUST00000018122.7
ENSMUST00000115355.1
ENSMUST00000115356.2
Cadps2
Ca2+-dependent activator protein for secretion 2
chr11_+_70459940 3.76 ENSMUST00000147289.1
ENSMUST00000126105.1
Zmynd15
zinc finger, MYND-type containing 15
chr5_+_114923234 3.70 ENSMUST00000031540.4
ENSMUST00000112143.3
Oasl1
2'-5' oligoadenylate synthetase-like 1
chr16_+_23609895 3.67 ENSMUST00000038423.5
Rtp4
receptor transporter protein 4
chr5_-_139814025 3.44 ENSMUST00000146780.1
Tmem184a
transmembrane protein 184a
chr11_-_83530505 3.31 ENSMUST00000035938.2
Ccl5
chemokine (C-C motif) ligand 5
chr11_-_48992226 3.24 ENSMUST00000059930.2
ENSMUST00000068063.3
Gm12185
Tgtp1
predicted gene 12185
T cell specific GTPase 1
chr3_-_151749877 3.20 ENSMUST00000029671.7
Ifi44
interferon-induced protein 44
chr8_-_71537402 3.13 ENSMUST00000051672.7
Bst2
bone marrow stromal cell antigen 2
chr6_+_90550789 3.12 ENSMUST00000130418.1
ENSMUST00000032175.8
Aldh1l1
aldehyde dehydrogenase 1 family, member L1
chr15_-_77596110 3.08 ENSMUST00000089465.4
Apol10b
apolipoprotein L 10B
chr2_+_155382186 3.06 ENSMUST00000134218.1
Trp53inp2
transformation related protein 53 inducible nuclear protein 2
chr1_-_173490933 2.97 ENSMUST00000160565.2
Gm4955
predicted gene 4955
chr9_-_48835932 2.91 ENSMUST00000093852.3
Zbtb16
zinc finger and BTB domain containing 16
chr16_-_35871544 2.89 ENSMUST00000042665.8
Parp14
poly (ADP-ribose) polymerase family, member 14
chr15_-_77533312 2.75 ENSMUST00000062562.5
Apol7c
apolipoprotein L 7c
chr9_-_106476590 2.75 ENSMUST00000112479.2
Parp3
poly (ADP-ribose) polymerase family, member 3
chr9_-_106476104 2.74 ENSMUST00000156426.1
Parp3
poly (ADP-ribose) polymerase family, member 3
chr3_+_81932601 2.72 ENSMUST00000029649.2
Ctso
cathepsin O
chr16_+_43235856 2.65 ENSMUST00000146708.1
Zbtb20
zinc finger and BTB domain containing 20
chr11_+_58215028 2.65 ENSMUST00000108836.1
Irgm2
immunity-related GTPase family M member 2
chr14_-_7994563 2.58 ENSMUST00000026315.7
Dnase1l3
deoxyribonuclease 1-like 3
chr11_+_58199556 2.56 ENSMUST00000035266.4
ENSMUST00000094169.4
ENSMUST00000168280.1
ENSMUST00000058704.8
Igtp
Irgm2
interferon gamma induced GTPase
immunity-related GTPase family M member 2
chr17_+_34187545 2.55 ENSMUST00000170086.1
Tap1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr3_+_142560052 2.54 ENSMUST00000106222.2
Gbp3
guanylate binding protein 3
chr1_-_173599074 2.53 ENSMUST00000150649.1
ENSMUST00000180215.1
ENSMUST00000097462.2
Pydc4
pyrin domain containing 4
chr3_+_142560108 2.50 ENSMUST00000128609.1
ENSMUST00000029935.7
Gbp3
guanylate binding protein 3
chr4_-_46536096 2.49 ENSMUST00000102924.2
Trim14
tripartite motif-containing 14
chr3_+_142560351 2.47 ENSMUST00000106221.1
Gbp3
guanylate binding protein 3
chr9_-_106476372 2.46 ENSMUST00000123555.1
ENSMUST00000125850.1
Parp3
poly (ADP-ribose) polymerase family, member 3
chr10_+_116301374 2.46 ENSMUST00000092167.5
Ptprb
protein tyrosine phosphatase, receptor type, B
chr18_-_3299537 2.44 ENSMUST00000129435.1
ENSMUST00000122958.1
Crem
cAMP responsive element modulator
chr17_-_34862122 2.40 ENSMUST00000154526.1
Cfb
complement factor B
chr6_+_121245903 2.40 ENSMUST00000032198.9
Usp18
ubiquitin specific peptidase 18
chr17_+_34187789 2.37 ENSMUST00000041633.8
Tap1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr4_-_46536134 2.37 ENSMUST00000046897.6
Trim14
tripartite motif-containing 14
chr7_-_141266415 2.29 ENSMUST00000106023.1
ENSMUST00000097952.2
ENSMUST00000026571.4
Irf7
interferon regulatory factor 7
chr1_+_173673651 2.27 ENSMUST00000085876.4
Pydc3
pyrin domain containing 3
chr7_+_107567445 2.25 ENSMUST00000120990.1
Olfml1
olfactomedin-like 1
chr5_-_139813237 2.22 ENSMUST00000110832.1
Tmem184a
transmembrane protein 184a
chr17_-_34862473 2.22 ENSMUST00000025229.4
ENSMUST00000176203.2
ENSMUST00000128767.1
Cfb
complement factor B
chr16_-_24393588 2.20 ENSMUST00000181640.1
1110054M08Rik
RIKEN cDNA 1110054M08 gene
chr16_+_10488175 2.19 ENSMUST00000023147.6
Ciita
class II transactivator
chr11_-_70459957 2.15 ENSMUST00000019064.2
Cxcl16
chemokine (C-X-C motif) ligand 16
chr2_-_36104060 2.10 ENSMUST00000112961.3
ENSMUST00000112966.3
Lhx6
LIM homeobox protein 6
chr7_-_104507812 2.09 ENSMUST00000033211.7
ENSMUST00000071069.6
Trim30d
tripartite motif-containing 30D
chr17_-_34187219 2.08 ENSMUST00000173831.1
Psmb9
proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)
chr4_+_108834601 2.07 ENSMUST00000030296.8
Txndc12
thioredoxin domain containing 12 (endoplasmic reticulum)
chr14_-_11162008 2.03 ENSMUST00000162278.1
ENSMUST00000160340.1
ENSMUST00000160956.1
Fhit
fragile histidine triad gene
chr12_+_103434211 1.95 ENSMUST00000079294.5
ENSMUST00000076788.5
ENSMUST00000076702.5
ENSMUST00000066701.6
ENSMUST00000085065.5
ENSMUST00000140838.1
Ifi27
interferon, alpha-inducible protein 27
chr2_-_181241955 1.93 ENSMUST00000121484.1
Helz2
helicase with zinc finger 2, transcriptional coactivator
chr1_+_175631996 1.92 ENSMUST00000040250.8
Kmo
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr3_+_19957088 1.92 ENSMUST00000108328.1
Cp
ceruloplasmin
chr11_-_100704217 1.92 ENSMUST00000017974.6
Dhx58
DEXH (Asp-Glu-X-His) box polypeptide 58
chr18_-_39489880 1.88 ENSMUST00000152853.1
Nr3c1
nuclear receptor subfamily 3, group C, member 1
chr1_+_52119438 1.87 ENSMUST00000070968.7
Stat1
signal transducer and activator of transcription 1
chr2_+_122147680 1.87 ENSMUST00000102476.4
B2m
beta-2 microglobulin
chr2_-_181242020 1.87 ENSMUST00000094203.4
ENSMUST00000108831.1
Helz2
helicase with zinc finger 2, transcriptional coactivator
chr11_-_48871408 1.86 ENSMUST00000097271.2
Irgm1
immunity-related GTPase family M member 1
chr18_-_3299452 1.86 ENSMUST00000126578.1
Crem
cAMP responsive element modulator
chr2_-_167062607 1.84 ENSMUST00000128676.1
Znfx1
zinc finger, NFX1-type containing 1
chr2_-_62646146 1.83 ENSMUST00000112459.3
ENSMUST00000028259.5
Ifih1
interferon induced with helicase C domain 1
chr1_+_175632169 1.80 ENSMUST00000097458.3
Kmo
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr1_-_105356658 1.79 ENSMUST00000058688.5
ENSMUST00000172299.1
Rnf152
ring finger protein 152
chr16_+_43364145 1.79 ENSMUST00000148775.1
Zbtb20
zinc finger and BTB domain containing 20
chr1_+_13668739 1.76 ENSMUST00000088542.3
Xkr9
X Kell blood group precursor related family member 9 homolog
chr5_-_91402905 1.75 ENSMUST00000121044.2
Btc
betacellulin, epidermal growth factor family member
chr3_+_19957037 1.70 ENSMUST00000091309.5
ENSMUST00000108329.1
ENSMUST00000003714.6
Cp
ceruloplasmin
chr7_-_126594941 1.66 ENSMUST00000058429.5
Il27
interleukin 27
chr14_+_28511344 1.62 ENSMUST00000112272.1
Wnt5a
wingless-related MMTV integration site 5A
chr12_+_37241729 1.61 ENSMUST00000160768.1
Agmo
alkylglycerol monooxygenase
chr11_+_48978889 1.58 ENSMUST00000179282.1
ENSMUST00000056759.4
Olfr56
olfactory receptor 56
chr6_-_39118211 1.57 ENSMUST00000038398.6
Parp12
poly (ADP-ribose) polymerase family, member 12
chr3_+_55116174 1.57 ENSMUST00000146109.1
Spg20
spastic paraplegia 20, spartin (Troyer syndrome) homolog (human)
chr3_+_19957240 1.56 ENSMUST00000108325.2
Cp
ceruloplasmin
chr5_-_120887582 1.55 ENSMUST00000086368.5
Oas1g
2'-5' oligoadenylate synthetase 1G
chr11_-_78984946 1.55 ENSMUST00000108268.3
Lgals9
lectin, galactose binding, soluble 9
chr19_-_4477447 1.52 ENSMUST00000059295.3
Syt12
synaptotagmin XII
chr4_+_135728116 1.52 ENSMUST00000102546.3
Il22ra1
interleukin 22 receptor, alpha 1
chr11_-_78984831 1.52 ENSMUST00000073001.4
ENSMUST00000108269.3
Lgals9
lectin, galactose binding, soluble 9
chr11_+_119393060 1.49 ENSMUST00000131035.2
ENSMUST00000093902.5
Rnf213
ring finger protein 213
chr11_+_72301613 1.48 ENSMUST00000151440.1
ENSMUST00000146233.1
ENSMUST00000140842.2
Xaf1
XIAP associated factor 1
chr3_+_94954075 1.47 ENSMUST00000107260.2
ENSMUST00000142311.1
ENSMUST00000137088.1
ENSMUST00000152869.1
ENSMUST00000107254.1
ENSMUST00000107253.1
Rfx5
regulatory factor X, 5 (influences HLA class II expression)
chr9_+_20868628 1.46 ENSMUST00000043911.7
A230050P20Rik
RIKEN cDNA A230050P20 gene
chr3_+_137671524 1.43 ENSMUST00000166899.2
Gm21962
predicted gene, 21962
chr10_+_13966268 1.43 ENSMUST00000015645.4
Hivep2
human immunodeficiency virus type I enhancer binding protein 2
chr11_-_48871344 1.43 ENSMUST00000049519.3
Irgm1
immunity-related GTPase family M member 1
chr11_+_49050733 1.39 ENSMUST00000102785.1
Olfr56
olfactory receptor 56
chr6_+_29529277 1.38 ENSMUST00000163511.1
Irf5
interferon regulatory factor 5
chr10_+_39612934 1.36 ENSMUST00000019987.6
Traf3ip2
TRAF3 interacting protein 2
chr13_+_74639866 1.34 ENSMUST00000169114.1
Erap1
endoplasmic reticulum aminopeptidase 1
chr1_+_58505135 1.31 ENSMUST00000160947.1
ENSMUST00000129740.2
ENSMUST00000139825.1
Gm15834
predicted gene 15834
chr16_+_24393350 1.30 ENSMUST00000038053.6
Lpp
LIM domain containing preferred translocation partner in lipoma
chr13_-_23710714 1.30 ENSMUST00000091707.6
ENSMUST00000006787.7
ENSMUST00000091706.6
Hfe
hemochromatosis
chr16_+_42907563 1.29 ENSMUST00000151244.1
ENSMUST00000114694.2
Zbtb20
zinc finger and BTB domain containing 20
chr16_+_35938470 1.28 ENSMUST00000114878.1
Parp9
poly (ADP-ribose) polymerase family, member 9
chr11_-_51857624 1.27 ENSMUST00000020655.7
ENSMUST00000109090.1
Phf15
PHD finger protein 15
chr2_-_132111440 1.24 ENSMUST00000128899.1
Slc23a2
solute carrier family 23 (nucleobase transporters), member 2
chr8_-_111338152 1.23 ENSMUST00000056157.7
ENSMUST00000120432.1
Mlkl
mixed lineage kinase domain-like
chr18_+_61045139 1.22 ENSMUST00000025522.4
ENSMUST00000115274.1
Pdgfrb
platelet derived growth factor receptor, beta polypeptide
chr17_+_43389436 1.21 ENSMUST00000113599.1
Gpr116
G protein-coupled receptor 116
chr1_+_132008285 1.21 ENSMUST00000146432.1
Elk4
ELK4, member of ETS oncogene family
chr7_+_104244496 1.21 ENSMUST00000106854.1
ENSMUST00000143414.1
Trim34a
tripartite motif-containing 34A
chr7_+_104244465 1.18 ENSMUST00000106848.1
Trim34a
tripartite motif-containing 34A
chr5_-_120777628 1.17 ENSMUST00000044833.8
Oas3
2'-5' oligoadenylate synthetase 3
chr5_-_92348871 1.17 ENSMUST00000038816.6
ENSMUST00000118006.1
Cxcl10
chemokine (C-X-C motif) ligand 10
chr19_-_21472552 1.17 ENSMUST00000087600.3
Gda
guanine deaminase
chr19_-_4477119 1.15 ENSMUST00000166191.1
Syt12
synaptotagmin XII
chr11_-_83020788 1.14 ENSMUST00000038141.8
ENSMUST00000092838.4
Slfn8
schlafen 8
chr1_+_171018920 1.13 ENSMUST00000078825.4
Fcgr4
Fc receptor, IgG, low affinity IV
chr10_+_128270546 1.13 ENSMUST00000105238.3
ENSMUST00000085708.2
Stat2
signal transducer and activator of transcription 2
chr1_-_78197112 1.11 ENSMUST00000087086.6
Pax3
paired box gene 3
chr10_-_94944578 1.11 ENSMUST00000099337.3
Plxnc1
plexin C1
chr5_-_120812484 1.11 ENSMUST00000125547.1
Oas1c
2'-5' oligoadenylate synthetase 1C
chr17_+_86167777 1.09 ENSMUST00000097275.2
Prkce
protein kinase C, epsilon
chr8_+_61928081 1.07 ENSMUST00000154398.1
ENSMUST00000093485.2
ENSMUST00000156980.1
ENSMUST00000070631.7
Ddx60
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
chr5_-_120812506 1.07 ENSMUST00000117193.1
ENSMUST00000130045.1
Oas1c
2'-5' oligoadenylate synthetase 1C
chr8_-_84773381 1.06 ENSMUST00000109764.1
Nfix
nuclear factor I/X
chr8_-_111337793 1.05 ENSMUST00000145862.1
Mlkl
mixed lineage kinase domain-like
chr19_+_6164433 1.05 ENSMUST00000045042.7
Batf2
basic leucine zipper transcription factor, ATF-like 2
chr16_-_35939082 1.04 ENSMUST00000081933.7
ENSMUST00000114885.1
Dtx3l
deltex 3-like (Drosophila)
chr8_+_127064107 1.04 ENSMUST00000162536.1
ENSMUST00000026921.6
ENSMUST00000162665.1
ENSMUST00000160766.1
ENSMUST00000162602.1
ENSMUST00000162531.1
ENSMUST00000160581.1
ENSMUST00000161355.1
ENSMUST00000159537.1
Pard3
par-3 (partitioning defective 3) homolog (C. elegans)
chr12_+_37242030 1.01 ENSMUST00000160390.1
Agmo
alkylglycerol monooxygenase
chr7_+_104244449 1.00 ENSMUST00000106849.2
ENSMUST00000060315.5
Trim34a
tripartite motif-containing 34A
chr1_+_85650008 0.99 ENSMUST00000054279.8
ENSMUST00000147552.1
ENSMUST00000153574.1
ENSMUST00000150967.1
Sp100
nuclear antigen Sp100
chr4_-_40239700 0.98 ENSMUST00000142055.1
Ddx58
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr1_-_78196832 0.97 ENSMUST00000004994.9
Pax3
paired box gene 3
chr12_+_90738201 0.97 ENSMUST00000181874.1
Gm26512
predicted gene, 26512
chr16_+_8470763 0.95 ENSMUST00000046470.9
ENSMUST00000150790.1
ENSMUST00000142899.1
Mettl22
methyltransferase like 22
chr3_+_66981352 0.95 ENSMUST00000162036.1
Rsrc1
arginine/serine-rich coiled-coil 1
chr1_+_85649988 0.95 ENSMUST00000155094.1
Sp100
nuclear antigen Sp100
chr15_-_76243401 0.95 ENSMUST00000165738.1
ENSMUST00000075689.6
Parp10
poly (ADP-ribose) polymerase family, member 10
chr19_-_6084873 0.95 ENSMUST00000160977.1
ENSMUST00000159859.1
Zfpl1
zinc finger like protein 1
chr4_-_40239779 0.94 ENSMUST00000037907.6
Ddx58
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr13_+_42866247 0.93 ENSMUST00000131942.1
Phactr1
phosphatase and actin regulator 1
chr16_+_35938972 0.93 ENSMUST00000023622.6
ENSMUST00000114877.1
Parp9
poly (ADP-ribose) polymerase family, member 9
chr1_-_170110491 0.92 ENSMUST00000027985.2
Ddr2
discoidin domain receptor family, member 2
chr12_+_37241633 0.92 ENSMUST00000049874.7
Agmo
alkylglycerol monooxygenase
chr6_+_39381175 0.90 ENSMUST00000031986.4
Rab19
RAB19, member RAS oncogene family
chr16_-_44139630 0.87 ENSMUST00000137557.1
ENSMUST00000147025.1
Atp6v1a
ATPase, H+ transporting, lysosomal V1 subunit A
chr2_-_173276144 0.87 ENSMUST00000139306.1
Pmepa1
prostate transmembrane protein, androgen induced 1
chr18_+_37400845 0.87 ENSMUST00000057228.1
Pcdhb9
protocadherin beta 9
chr14_+_55604550 0.85 ENSMUST00000138037.1
Irf9
interferon regulatory factor 9
chr11_+_43474276 0.85 ENSMUST00000173002.1
ENSMUST00000057679.3
C1qtnf2
C1q and tumor necrosis factor related protein 2
chr4_+_45972233 0.85 ENSMUST00000102929.1
Tdrd7
tudor domain containing 7
chr9_+_118478344 0.82 ENSMUST00000035020.8
Eomes
eomesodermin homolog (Xenopus laevis)
chr14_-_63543931 0.82 ENSMUST00000058679.5
Mtmr9
myotubularin related protein 9
chr6_-_125231772 0.80 ENSMUST00000043422.7
Tapbpl
TAP binding protein-like
chr7_+_104300230 0.78 ENSMUST00000106847.1
Trim34b
tripartite motif-containing 34B
chr18_-_39490649 0.78 ENSMUST00000115567.1
Nr3c1
nuclear receptor subfamily 3, group C, member 1
chr2_-_84743655 0.77 ENSMUST00000181711.1
Gm19426
predicted gene, 19426
chr1_+_180942500 0.77 ENSMUST00000159436.1
Tmem63a
transmembrane protein 63a
chr14_+_48446128 0.77 ENSMUST00000124720.1
Tmem260
transmembrane protein 260
chr4_+_138972885 0.76 ENSMUST00000123636.1
ENSMUST00000043042.3
ENSMUST00000050949.2
Tmco4
transmembrane and coiled-coil domains 4
chr7_+_44836286 0.76 ENSMUST00000033015.7
Il4i1
interleukin 4 induced 1
chr1_+_85650044 0.76 ENSMUST00000066427.4
Sp100
nuclear antigen Sp100
chr11_-_83020722 0.76 ENSMUST00000108152.2
Slfn8
schlafen 8
chr8_+_127064022 0.75 ENSMUST00000160272.1
ENSMUST00000079777.5
ENSMUST00000162907.1
Pard3
par-3 (partitioning defective 3) homolog (C. elegans)
chr5_+_114896936 0.72 ENSMUST00000031542.9
ENSMUST00000146072.1
ENSMUST00000150361.1
Oasl2
2'-5' oligoadenylate synthetase-like 2
chr10_+_63061582 0.69 ENSMUST00000020266.8
ENSMUST00000178684.1
Pbld1
phenazine biosynthesis-like protein domain containing 1
chr19_+_12460749 0.68 ENSMUST00000081035.7
Mpeg1
macrophage expressed gene 1
chr1_+_143640664 0.68 ENSMUST00000038252.2
B3galt2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr7_-_46795881 0.67 ENSMUST00000107653.1
ENSMUST00000107654.1
ENSMUST00000014562.7
ENSMUST00000152759.1
Hps5
Hermansky-Pudlak syndrome 5 homolog (human)
chr4_+_94739518 0.66 ENSMUST00000071168.5
Tek
endothelial-specific receptor tyrosine kinase
chr9_+_32116040 0.64 ENSMUST00000174641.1
Arhgap32
Rho GTPase activating protein 32
chr5_-_90223923 0.63 ENSMUST00000118816.1
ENSMUST00000048363.7
Cox18
cytochrome c oxidase assembly protein 18
chr5_-_120907510 0.62 ENSMUST00000080322.7
Oas1a
2'-5' oligoadenylate synthetase 1A
chr6_+_57580992 0.60 ENSMUST00000031817.8
Herc6
hect domain and RLD 6
chr1_-_173912904 0.60 ENSMUST00000009340.8
Mnda
myeloid cell nuclear differentiation antigen
chr7_-_46795661 0.60 ENSMUST00000123725.1
Hps5
Hermansky-Pudlak syndrome 5 homolog (human)

Network of associatons between targets according to the STRING database.

First level regulatory network of Stat2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.4 13.6 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
3.3 10.0 GO:2000547 regulation of dendritic cell dendrite assembly(GO:2000547)
2.7 8.0 GO:1990166 protein localization to site of double-strand break(GO:1990166)
2.1 6.3 GO:0006533 aspartate catabolic process(GO:0006533)
1.9 5.7 GO:1904933 regulation of cell proliferation in midbrain(GO:1904933)
1.3 5.2 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
1.1 2.1 GO:0002589 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589)
1.0 3.1 GO:0009258 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
1.0 4.2 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
1.0 3.0 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
1.0 4.9 GO:0046967 cytosol to ER transport(GO:0046967)
1.0 3.8 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.9 5.7 GO:0018992 germ-line sex determination(GO:0018992)
0.9 1.9 GO:0002481 antigen processing and presentation of exogenous peptide antigen via MHC class Ib(GO:0002477) antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent(GO:0002481)
0.9 23.2 GO:0035455 response to interferon-alpha(GO:0035455)
0.8 3.3 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.8 3.1 GO:2000562 negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.7 3.3 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.7 3.9 GO:1900142 regulation of oligodendrocyte apoptotic process(GO:1900141) negative regulation of oligodendrocyte apoptotic process(GO:1900142) regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.6 5.8 GO:0072602 interleukin-4 secretion(GO:0072602)
0.6 3.7 GO:0035549 interferon-beta secretion(GO:0035546) regulation of interferon-beta secretion(GO:0035547) positive regulation of interferon-beta secretion(GO:0035549)
0.6 3.7 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.6 9.3 GO:0031000 response to caffeine(GO:0031000)
0.6 7.9 GO:0060340 positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.5 1.6 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.5 3.0 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.5 3.8 GO:1990504 dense core granule exocytosis(GO:1990504)
0.4 16.3 GO:0035456 response to interferon-beta(GO:0035456)
0.4 1.2 GO:0070904 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.4 1.2 GO:0072276 cell migration involved in vasculogenesis(GO:0035441) metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.4 1.2 GO:0046098 guanine metabolic process(GO:0046098)
0.4 1.9 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.4 2.9 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
0.4 2.1 GO:0021853 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.3 1.0 GO:0060809 mesodermal to mesenchymal transition involved in gastrulation(GO:0060809)
0.3 1.8 GO:0003383 apical constriction(GO:0003383)
0.3 1.2 GO:1901740 negative regulation of myoblast fusion(GO:1901740)
0.3 4.6 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.3 2.2 GO:0045348 positive regulation of MHC class II biosynthetic process(GO:0045348)
0.3 1.1 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.3 2.0 GO:0015961 diadenosine polyphosphate catabolic process(GO:0015961)
0.2 11.7 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.2 8.7 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.2 0.7 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.2 3.5 GO:0046485 ether lipid metabolic process(GO:0046485)
0.2 1.7 GO:0060330 regulation of response to interferon-gamma(GO:0060330)
0.2 0.6 GO:0007208 phospholipase C-activating serotonin receptor signaling pathway(GO:0007208)
0.2 3.6 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.2 2.1 GO:0014807 regulation of somitogenesis(GO:0014807)
0.2 4.5 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.2 0.6 GO:1902867 negative regulation of neural retina development(GO:0061076) negative regulation of retina development in camera-type eye(GO:1902867) negative regulation of amacrine cell differentiation(GO:1902870)
0.2 1.7 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.2 6.6 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.2 0.5 GO:0048687 positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691)
0.2 1.2 GO:0045351 type I interferon biosynthetic process(GO:0045351)
0.2 0.5 GO:0072734 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.2 1.8 GO:0035810 positive regulation of urine volume(GO:0035810)
0.2 5.2 GO:0046688 response to copper ion(GO:0046688)
0.2 2.6 GO:0010623 programmed cell death involved in cell development(GO:0010623)
0.1 1.2 GO:0060700 regulation of ribonuclease activity(GO:0060700)
0.1 1.1 GO:0071357 type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.1 1.5 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.1 0.9 GO:0010990 regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991)
0.1 1.8 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.1 0.9 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.1 0.6 GO:0051204 protein insertion into mitochondrial membrane(GO:0051204)
0.1 0.4 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
0.1 1.2 GO:0070932 histone H3 deacetylation(GO:0070932)
0.1 4.9 GO:0006953 acute-phase response(GO:0006953)
0.1 1.9 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.1 0.5 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.1 2.4 GO:0035634 response to stilbenoid(GO:0035634)
0.1 1.7 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
0.1 10.4 GO:0007586 digestion(GO:0007586)
0.1 5.0 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.1 0.9 GO:0032494 response to peptidoglycan(GO:0032494)
0.1 0.5 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.1 2.7 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 0.3 GO:0048014 Tie signaling pathway(GO:0048014)
0.1 0.2 GO:0061386 closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 1.1 GO:0021707 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.1 0.2 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.1 1.1 GO:0042119 neutrophil activation(GO:0042119)
0.1 0.5 GO:0048207 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.0 1.0 GO:0042832 defense response to protozoan(GO:0042832)
0.0 0.2 GO:0090168 Golgi reassembly(GO:0090168)
0.0 5.9 GO:0019395 fatty acid oxidation(GO:0019395)
0.0 0.2 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.0 1.9 GO:0070207 protein homotrimerization(GO:0070207)
0.0 3.1 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 1.5 GO:0034341 response to interferon-gamma(GO:0034341)
0.0 0.4 GO:0021678 third ventricle development(GO:0021678)
0.0 0.3 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0 0.1 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.0 0.9 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.1 GO:0043974 histone H3-K27 acetylation(GO:0043974) leukemia inhibitory factor signaling pathway(GO:0048861) regulation of histone H3-K27 acetylation(GO:1901674)
0.0 1.1 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.0 1.0 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.2 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.0 0.5 GO:0032689 negative regulation of interferon-gamma production(GO:0032689)
0.0 0.3 GO:0048305 immunoglobulin secretion(GO:0048305)
0.0 0.5 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.0 1.3 GO:0019882 antigen processing and presentation(GO:0019882)
0.0 0.3 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.0 2.7 GO:0007608 sensory perception of smell(GO:0007608)
0.0 1.8 GO:0007286 spermatid development(GO:0007286)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 12.7 GO:0020003 symbiont-containing vacuole(GO:0020003)
0.7 5.5 GO:0042825 TAP complex(GO:0042825)
0.4 3.9 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867) insulin-like growth factor ternary complex(GO:0042567)
0.4 2.1 GO:1990111 spermatoproteasome complex(GO:1990111)
0.4 3.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.3 1.3 GO:0031084 BLOC-2 complex(GO:0031084)
0.3 13.6 GO:0055038 recycling endosome membrane(GO:0055038)
0.2 1.8 GO:0033269 internode region of axon(GO:0033269)
0.2 3.3 GO:0044754 autolysosome(GO:0044754)
0.2 1.7 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.2 6.5 GO:0035861 site of double-strand break(GO:0035861)
0.1 6.5 GO:0031901 early endosome membrane(GO:0031901)
0.1 5.2 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 0.1 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 3.3 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 8.1 GO:0072562 blood microparticle(GO:0072562)
0.0 0.9 GO:0033391 chromatoid body(GO:0033391)
0.0 3.1 GO:0005776 autophagosome(GO:0005776)
0.0 2.0 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 3.8 GO:0042734 presynaptic membrane(GO:0042734)
0.0 6.3 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 53.5 GO:0005615 extracellular space(GO:0005615)
0.0 6.5 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 12.0 GO:0045177 apical part of cell(GO:0045177)
0.0 0.6 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.2 GO:0033176 proton-transporting V-type ATPase complex(GO:0033176)
0.0 1.0 GO:0032587 ruffle membrane(GO:0032587)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.1 GO:0003692 left-handed Z-DNA binding(GO:0003692)
1.6 6.3 GO:0003884 D-amino-acid oxidase activity(GO:0003884)
1.5 6.0 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
1.5 14.7 GO:0019763 immunoglobulin receptor activity(GO:0019763)
1.4 5.8 GO:0002114 interleukin-33 receptor activity(GO:0002114)
1.2 3.5 GO:0050479 glyceryl-ether monooxygenase activity(GO:0050479)
1.1 3.3 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
1.0 3.1 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
1.0 4.9 GO:0046980 peptide antigen-transporting ATPase activity(GO:0015433) tapasin binding(GO:0046980)
0.9 3.6 GO:0031849 olfactory receptor binding(GO:0031849)
0.9 8.0 GO:0003909 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.8 9.3 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.7 2.1 GO:0019153 protein-disulfide reductase (glutathione) activity(GO:0019153)
0.7 6.6 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.6 3.7 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.6 3.0 GO:0004883 glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.5 1.6 GO:0005110 frizzled-2 binding(GO:0005110)
0.5 5.2 GO:0051434 BH3 domain binding(GO:0051434)
0.5 5.2 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.5 1.5 GO:0042015 interleukin-20 binding(GO:0042015)
0.5 2.0 GO:0047710 bis(5'-adenosyl)-triphosphatase activity(GO:0047710)
0.5 16.9 GO:0008009 chemokine activity(GO:0008009)
0.4 3.1 GO:0016936 galactoside binding(GO:0016936)
0.4 1.2 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.3 0.6 GO:0046978 TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
0.3 1.1 GO:0035276 ethanol binding(GO:0035276)
0.3 5.7 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.3 0.8 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.2 1.2 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.2 1.9 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.2 2.9 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.2 0.7 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.1 1.3 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.1 1.3 GO:0039706 co-receptor binding(GO:0039706)
0.1 2.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 25.7 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 3.9 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 0.9 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 2.1 GO:0070628 proteasome binding(GO:0070628)
0.1 4.2 GO:0043531 ADP binding(GO:0043531)
0.1 0.5 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.1 1.1 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 0.5 GO:0033142 progesterone receptor binding(GO:0033142)
0.1 2.0 GO:0005521 lamin binding(GO:0005521)
0.1 0.3 GO:0070052 collagen V binding(GO:0070052)
0.1 5.5 GO:0003725 double-stranded RNA binding(GO:0003725)
0.1 19.0 GO:0003924 GTPase activity(GO:0003924)
0.1 1.6 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1 6.9 GO:0020037 heme binding(GO:0020037)
0.1 2.1 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.5 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.6 GO:0051378 serotonin binding(GO:0051378)
0.0 0.2 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.0 9.1 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 1.8 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 2.7 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 4.9 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.1 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.0 0.2 GO:0001515 opioid peptide activity(GO:0001515)
0.0 2.7 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 1.8 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 2.1 GO:0004520 endodeoxyribonuclease activity(GO:0004520)
0.0 2.6 GO:0036459 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 2.8 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 3.0 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.9 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.9 GO:0050699 WW domain binding(GO:0050699)
0.0 6.3 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 0.4 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 1.0 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 2.7 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.3 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.5 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.6 GO:0030332 cyclin binding(GO:0030332)
0.0 0.6 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.2 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 3.1 GO:0001047 core promoter binding(GO:0001047)
0.0 1.9 GO:0004386 helicase activity(GO:0004386)
0.0 1.0 GO:0008276 protein methyltransferase activity(GO:0008276)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.9 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.2 4.6 ST G ALPHA S PATHWAY G alpha s Pathway
0.2 15.9 PID IL4 2PATHWAY IL4-mediated signaling events
0.2 11.8 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 6.6 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.1 5.8 PID IL1 PATHWAY IL1-mediated signaling events
0.1 3.9 PID IGF1 PATHWAY IGF1 pathway
0.1 1.7 PID IL27 PATHWAY IL27-mediated signaling events
0.1 3.9 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.1 1.8 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 6.2 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.1 5.2 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.1 5.3 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.1 12.5 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 2.3 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 2.1 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 1.2 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 2.0 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 1.2 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.8 PID SHP2 PATHWAY SHP2 signaling
0.0 5.0 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.9 PID AURORA A PATHWAY Aurora A signaling
0.0 0.5 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 2.8 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 1.0 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.7 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 9.3 REACTOME DEFENSINS Genes involved in Defensins
0.6 1.9 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.3 4.6 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.3 6.3 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.3 6.0 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.3 12.7 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.3 4.9 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.2 5.6 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.2 3.2 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.2 7.5 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.1 4.2 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 5.2 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 5.3 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.1 9.6 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 2.7 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 1.2 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 1.8 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 0.8 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.1 1.8 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.1 1.8 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.1 0.6 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 1.3 REACTOME RIG I MDA5 MEDIATED INDUCTION OF IFN ALPHA BETA PATHWAYS Genes involved in RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
0.0 1.1 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 1.1 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 2.7 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 1.2 REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.0 0.3 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 1.2 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.5 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.5 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 1.2 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 2.1 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.1 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling