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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Nfix

Z-value: 1.24

Motif logo

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Transcription factors associated with Nfix

Gene Symbol Gene ID Gene Info
Nfix
ENSMUSG00000001911.10 nuclear factor I/X

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nfixmm10_v2_chr8_-_84773381_847734270.447.1e-03Click!

Activity profile of Nfix motif

Sorted Z-values of Nfix motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_97417730 9.89 ENSMUST00000043077.7
Thrsp
thyroid hormone responsive
chr8_-_93131271 4.68 ENSMUST00000034189.8
Ces1c
carboxylesterase 1C
chr7_+_140763739 4.38 ENSMUST00000026552.7
Cyp2e1
cytochrome P450, family 2, subfamily e, polypeptide 1
chr7_+_140845562 4.19 ENSMUST00000035300.5
Scgb1c1
secretoglobin, family 1C, member 1
chr5_-_77115145 3.69 ENSMUST00000081964.5
Hopx
HOP homeobox
chr6_-_141856171 3.20 ENSMUST00000165990.1
ENSMUST00000163678.1
Slco1a4
solute carrier organic anion transporter family, member 1a4
chr10_-_109010955 2.95 ENSMUST00000105276.1
ENSMUST00000064054.7
Syt1
synaptotagmin I
chr19_-_46672883 2.89 ENSMUST00000026012.7
Cyp17a1
cytochrome P450, family 17, subfamily a, polypeptide 1
chr3_-_129332713 2.86 ENSMUST00000029658.7
Enpep
glutamyl aminopeptidase
chr5_-_87337165 2.66 ENSMUST00000031195.2
Ugt2a3
UDP glucuronosyltransferase 2 family, polypeptide A3
chr19_+_44333092 2.59 ENSMUST00000058856.8
Scd4
stearoyl-coenzyme A desaturase 4
chr7_-_48848023 2.55 ENSMUST00000032658.6
Csrp3
cysteine and glycine-rich protein 3
chr11_-_78422217 2.33 ENSMUST00000001122.5
Slc13a2
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
chr14_+_65666394 2.29 ENSMUST00000022610.8
Scara5
scavenger receptor class A, member 5 (putative)
chr10_+_57784859 2.18 ENSMUST00000020024.5
Fabp7
fatty acid binding protein 7, brain
chr10_+_57784914 2.01 ENSMUST00000165013.1
Fabp7
fatty acid binding protein 7, brain
chr1_+_88070765 1.89 ENSMUST00000073772.4
Ugt1a9
UDP glucuronosyltransferase 1 family, polypeptide A9
chr19_-_43524462 1.88 ENSMUST00000026196.7
Got1
glutamate oxaloacetate transaminase 1, soluble
chr5_-_87092546 1.72 ENSMUST00000132667.1
ENSMUST00000145617.1
ENSMUST00000094649.4
Ugt2b36
UDP glucuronosyltransferase 2 family, polypeptide B36
chr16_+_42907563 1.61 ENSMUST00000151244.1
ENSMUST00000114694.2
Zbtb20
zinc finger and BTB domain containing 20
chr10_-_24101951 1.61 ENSMUST00000170267.1
Taar8c
trace amine-associated receptor 8C
chr11_-_89302545 1.60 ENSMUST00000061728.3
Nog
noggin
chr2_+_122147680 1.58 ENSMUST00000102476.4
B2m
beta-2 microglobulin
chr4_-_141623799 1.55 ENSMUST00000038661.7
Slc25a34
solute carrier family 25, member 34
chr11_+_101367542 1.52 ENSMUST00000019469.2
G6pc
glucose-6-phosphatase, catalytic
chr14_+_65666430 1.46 ENSMUST00000069226.6
Scara5
scavenger receptor class A, member 5 (putative)
chrX_-_143933089 1.41 ENSMUST00000087313.3
Dcx
doublecortin
chr10_-_89506631 1.40 ENSMUST00000058126.8
ENSMUST00000105296.2
Nr1h4
nuclear receptor subfamily 1, group H, member 4
chr5_+_90460889 1.40 ENSMUST00000031314.8
Alb
albumin
chr11_+_78290841 1.39 ENSMUST00000046361.4
BC030499
cDNA sequence BC030499
chr17_-_73950172 1.36 ENSMUST00000024866.4
Xdh
xanthine dehydrogenase
chr15_-_101924725 1.34 ENSMUST00000023797.6
Krt4
keratin 4
chr1_+_133365160 1.32 ENSMUST00000129213.1
Etnk2
ethanolamine kinase 2
chrX_+_38316177 1.30 ENSMUST00000016471.2
ENSMUST00000115134.1
Atp1b4
ATPase, (Na+)/K+ transporting, beta 4 polypeptide
chr3_-_145032765 1.30 ENSMUST00000029919.5
Clca3
chloride channel calcium activated 3
chr11_-_100121558 1.28 ENSMUST00000007275.2
Krt13
keratin 13
chr1_-_162898484 1.25 ENSMUST00000143123.1
Fmo2
flavin containing monooxygenase 2
chr5_+_92387846 1.24 ENSMUST00000138687.1
ENSMUST00000124509.1
Art3
ADP-ribosyltransferase 3
chr17_-_24209377 1.24 ENSMUST00000024931.4
Ntn3
netrin 3
chrX_-_8193387 1.24 ENSMUST00000143223.1
ENSMUST00000033509.8
Ebp
phenylalkylamine Ca2+ antagonist (emopamil) binding protein
chr4_-_46991842 1.23 ENSMUST00000107749.2
Gabbr2
gamma-aminobutyric acid (GABA) B receptor, 2
chr7_+_131032061 1.23 ENSMUST00000084509.3
Dmbt1
deleted in malignant brain tumors 1
chr5_+_92387673 1.21 ENSMUST00000145072.1
Art3
ADP-ribosyltransferase 3
chr9_-_103222063 1.19 ENSMUST00000170904.1
Trf
transferrin
chrX_-_100412587 1.18 ENSMUST00000033567.8
Awat2
acyl-CoA wax alcohol acyltransferase 2
chr11_-_116654245 1.14 ENSMUST00000021166.5
Cygb
cytoglobin
chr6_+_78380700 1.09 ENSMUST00000101272.1
Reg3a
regenerating islet-derived 3 alpha
chr15_+_10952332 1.08 ENSMUST00000022853.8
ENSMUST00000110523.1
C1qtnf3
C1q and tumor necrosis factor related protein 3
chr7_-_119479249 1.08 ENSMUST00000033263.4
Umod
uromodulin
chr7_-_90129339 1.07 ENSMUST00000181189.1
2310010J17Rik
RIKEN cDNA 2310010J17 gene
chr6_-_136875794 1.07 ENSMUST00000032342.1
Mgp
matrix Gla protein
chr11_+_99864476 1.04 ENSMUST00000092694.3
Gm11559
predicted gene 11559
chr18_+_43963234 1.03 ENSMUST00000069245.7
Spink5
serine peptidase inhibitor, Kazal type 5
chr13_-_41847626 1.03 ENSMUST00000121404.1
Adtrp
androgen dependent TFPI regulating protein
chr6_+_141524379 1.01 ENSMUST00000032362.9
Slco1c1
solute carrier organic anion transporter family, member 1c1
chr2_+_32646586 1.00 ENSMUST00000009705.7
ENSMUST00000167841.1
Eng
endoglin
chr16_+_41532851 0.96 ENSMUST00000078873.4
Lsamp
limbic system-associated membrane protein
chr16_+_43235856 0.95 ENSMUST00000146708.1
Zbtb20
zinc finger and BTB domain containing 20
chr3_+_92288566 0.95 ENSMUST00000090872.4
Sprr2a3
small proline-rich protein 2A3
chr1_+_87594545 0.93 ENSMUST00000165109.1
ENSMUST00000070898.5
Neu2
neuraminidase 2
chr13_-_41847599 0.91 ENSMUST00000179758.1
Adtrp
androgen dependent TFPI regulating protein
chr12_-_75735729 0.91 ENSMUST00000021450.4
Sgpp1
sphingosine-1-phosphate phosphatase 1
chr4_+_82065924 0.91 ENSMUST00000161588.1
Gm5860
predicted gene 5860
chr7_+_27195781 0.90 ENSMUST00000108379.1
ENSMUST00000179391.1
BC024978
cDNA sequence BC024978
chr5_+_24413406 0.90 ENSMUST00000049346.5
Asic3
acid-sensing (proton-gated) ion channel 3
chr7_+_28180226 0.90 ENSMUST00000172467.1
Dyrk1b
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr2_+_133552159 0.88 ENSMUST00000028836.6
Bmp2
bone morphogenetic protein 2
chr3_-_39359128 0.88 ENSMUST00000056409.2
Gm9845
predicted pseudogene 9845
chr7_-_105399991 0.88 ENSMUST00000118726.1
ENSMUST00000074686.7
ENSMUST00000122327.1
ENSMUST00000179474.1
ENSMUST00000048079.6
Fam160a2
family with sequence similarity 160, member A2
chr7_+_28180272 0.86 ENSMUST00000173223.1
Dyrk1b
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr15_-_101712891 0.85 ENSMUST00000023709.5
Krt5
keratin 5
chr6_+_78370877 0.85 ENSMUST00000096904.3
Reg3b
regenerating islet-derived 3 beta
chr3_+_123267445 0.85 ENSMUST00000047923.7
Sec24d
Sec24 related gene family, member D (S. cerevisiae)
chr11_-_43836243 0.84 ENSMUST00000167574.1
Adra1b
adrenergic receptor, alpha 1b
chr4_+_102430047 0.84 ENSMUST00000172616.1
Pde4b
phosphodiesterase 4B, cAMP specific
chr3_-_89279633 0.83 ENSMUST00000118860.1
ENSMUST00000029566.2
Efna1
ephrin A1
chr4_-_129227883 0.82 ENSMUST00000106051.1
C77080
expressed sequence C77080
chr12_-_56535047 0.80 ENSMUST00000178477.2
Nkx2-1
NK2 homeobox 1
chr8_+_31091593 0.78 ENSMUST00000161713.1
Dusp26
dual specificity phosphatase 26 (putative)
chr1_-_163725123 0.78 ENSMUST00000159679.1
Mettl11b
methyltransferase like 11B
chr17_-_34862122 0.78 ENSMUST00000154526.1
Cfb
complement factor B
chr2_-_71750083 0.77 ENSMUST00000180494.1
Gm17250
predicted gene, 17250
chr8_-_119635553 0.75 ENSMUST00000061828.3
Kcng4
potassium voltage-gated channel, subfamily G, member 4
chr12_-_76795489 0.75 ENSMUST00000082431.3
Gpx2
glutathione peroxidase 2
chr4_-_119415494 0.74 ENSMUST00000063642.2
Ccdc30
coiled-coil domain containing 30
chr17_-_34862473 0.74 ENSMUST00000025229.4
ENSMUST00000176203.2
ENSMUST00000128767.1
Cfb
complement factor B
chr18_-_39490649 0.73 ENSMUST00000115567.1
Nr3c1
nuclear receptor subfamily 3, group C, member 1
chr4_+_82065855 0.73 ENSMUST00000151038.1
Gm5860
predicted gene 5860
chr15_-_64922290 0.72 ENSMUST00000023007.5
Adcy8
adenylate cyclase 8
chr6_+_139843648 0.72 ENSMUST00000087657.6
Pik3c2g
phosphatidylinositol 3-kinase, C2 domain containing, gamma polypeptide
chr10_-_95415484 0.72 ENSMUST00000172070.1
ENSMUST00000150432.1
Socs2
suppressor of cytokine signaling 2
chr17_-_35626634 0.70 ENSMUST00000164502.2
Gm9573
predicted gene 9573
chrX_+_101377267 0.70 ENSMUST00000052130.7
Gjb1
gap junction protein, beta 1
chr17_+_45506825 0.70 ENSMUST00000024733.7
Aars2
alanyl-tRNA synthetase 2, mitochondrial (putative)
chr10_-_127370535 0.68 ENSMUST00000026472.8
Inhbc
inhibin beta-C
chr2_-_26092149 0.68 ENSMUST00000114159.2
Nacc2
nucleus accumbens associated 2, BEN and BTB (POZ) domain containing
chr8_-_64733534 0.68 ENSMUST00000141021.1
Sc4mol
sterol-C4-methyl oxidase-like
chr4_+_102570065 0.68 ENSMUST00000097950.2
Pde4b
phosphodiesterase 4B, cAMP specific
chr6_-_126166726 0.68 ENSMUST00000112244.2
ENSMUST00000050484.7
Ntf3
neurotrophin 3
chr4_-_129261394 0.67 ENSMUST00000145261.1
C77080
expressed sequence C77080
chr16_-_3908639 0.67 ENSMUST00000115859.1
1700037C18Rik
RIKEN cDNA 1700037C18 gene
chr7_+_130936172 0.66 ENSMUST00000006367.7
Htra1
HtrA serine peptidase 1
chr1_+_169929929 0.66 ENSMUST00000175731.1
1700084C01Rik
RIKEN cDNA 1700084C01 gene
chr8_+_94472763 0.64 ENSMUST00000053085.5
Nlrc5
NLR family, CARD domain containing 5
chr11_+_77462605 0.64 ENSMUST00000130255.1
Coro6
coronin 6
chr18_-_23038656 0.64 ENSMUST00000081423.6
Nol4
nucleolar protein 4
chr9_+_89199319 0.64 ENSMUST00000138109.1
Mthfs
5, 10-methenyltetrahydrofolate synthetase
chr19_-_34879452 0.63 ENSMUST00000036584.5
Pank1
pantothenate kinase 1
chr11_+_115462464 0.63 ENSMUST00000106532.3
ENSMUST00000092445.5
ENSMUST00000153466.1
Slc16a5
solute carrier family 16 (monocarboxylic acid transporters), member 5
chr10_-_40142247 0.63 ENSMUST00000092566.6
Slc16a10
solute carrier family 16 (monocarboxylic acid transporters), member 10
chr5_-_84417359 0.62 ENSMUST00000113401.1
Epha5
Eph receptor A5
chr11_+_67798269 0.62 ENSMUST00000168612.1
ENSMUST00000040574.4
Dhrs7c
dehydrogenase/reductase (SDR family) member 7C
chr7_-_15879844 0.61 ENSMUST00000172758.1
ENSMUST00000044434.6
Crx
cone-rod homeobox containing gene
chr12_-_55492587 0.60 ENSMUST00000021413.7
Nfkbia
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha
chr15_-_78206391 0.60 ENSMUST00000120592.1
Pvalb
parvalbumin
chr6_-_125313844 0.60 ENSMUST00000032489.7
Ltbr
lymphotoxin B receptor
chr7_+_28179469 0.59 ENSMUST00000085901.6
ENSMUST00000172761.1
Dyrk1b
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr5_+_120511213 0.59 ENSMUST00000111890.2
ENSMUST00000076051.5
ENSMUST00000147496.1
Slc8b1
solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
chr7_+_114745685 0.59 ENSMUST00000136645.1
ENSMUST00000169913.1
Insc
inscuteable homolog (Drosophila)
chrX_-_48208566 0.58 ENSMUST00000037960.4
Zdhhc9
zinc finger, DHHC domain containing 9
chr5_-_86906937 0.58 ENSMUST00000031181.9
ENSMUST00000113333.1
Ugt2b34
UDP glucuronosyltransferase 2 family, polypeptide B34
chr6_-_33060256 0.58 ENSMUST00000066379.4
Chchd3
coiled-coil-helix-coiled-coil-helix domain containing 3
chr5_-_124352233 0.57 ENSMUST00000111472.1
Cdk2ap1
CDK2 (cyclin-dependent kinase 2)-associated protein 1
chr1_+_88055467 0.56 ENSMUST00000173325.1
Ugt1a10
UDP glycosyltransferase 1 family, polypeptide A10
chr13_-_26770157 0.56 ENSMUST00000055915.3
Hdgfl1
hepatoma derived growth factor-like 1
chr2_-_160327494 0.55 ENSMUST00000099127.2
Gm826
predicted gene 826
chr6_-_5256226 0.55 ENSMUST00000125686.1
ENSMUST00000031773.2
Pon3
paraoxonase 3
chr5_-_103977326 0.55 ENSMUST00000120320.1
Hsd17b13
hydroxysteroid (17-beta) dehydrogenase 13
chr7_-_132599637 0.54 ENSMUST00000054562.3
Nkx1-2
NK1 transcription factor related, locus 2 (Drosophila)
chrX_-_48208870 0.54 ENSMUST00000088935.3
Zdhhc9
zinc finger, DHHC domain containing 9
chr19_-_11829024 0.54 ENSMUST00000061235.2
Olfr1417
olfactory receptor 1417
chr6_+_34746368 0.54 ENSMUST00000142716.1
Cald1
caldesmon 1
chr14_+_65837302 0.53 ENSMUST00000022614.5
Ccdc25
coiled-coil domain containing 25
chr13_+_41655697 0.52 ENSMUST00000067176.8
Gm5082
predicted gene 5082
chr4_+_139653538 0.52 ENSMUST00000030510.7
ENSMUST00000166773.1
Tas1r2
taste receptor, type 1, member 2
chr2_-_147186389 0.51 ENSMUST00000109970.3
ENSMUST00000067075.5
Nkx2-2
NK2 homeobox 2
chr10_+_4611971 0.51 ENSMUST00000105590.1
ENSMUST00000067086.7
Esr1
estrogen receptor 1 (alpha)
chr19_+_46623387 0.51 ENSMUST00000111855.4
Wbp1l
WW domain binding protein 1 like
chr6_-_33060172 0.50 ENSMUST00000115091.1
ENSMUST00000127666.1
Chchd3
coiled-coil-helix-coiled-coil-helix domain containing 3
chr6_+_127015542 0.50 ENSMUST00000000187.5
Fgf6
fibroblast growth factor 6
chr3_+_90080442 0.50 ENSMUST00000127955.1
Tpm3
tropomyosin 3, gamma
chr9_-_87731248 0.49 ENSMUST00000034991.7
Tbx18
T-box18
chr11_+_98383811 0.49 ENSMUST00000008021.2
Tcap
titin-cap
chr11_-_84068357 0.49 ENSMUST00000100705.4
Dusp14
dual specificity phosphatase 14
chr5_+_65934922 0.49 ENSMUST00000153624.1
Chrna9
cholinergic receptor, nicotinic, alpha polypeptide 9
chr5_-_103977404 0.48 ENSMUST00000112803.2
Hsd17b13
hydroxysteroid (17-beta) dehydrogenase 13
chr1_-_56969864 0.47 ENSMUST00000177424.1
Satb2
special AT-rich sequence binding protein 2
chr8_-_83955205 0.47 ENSMUST00000098595.2
Gm10644
predicted gene 10644
chr5_-_103977360 0.47 ENSMUST00000048118.8
Hsd17b13
hydroxysteroid (17-beta) dehydrogenase 13
chr11_+_67238017 0.46 ENSMUST00000018632.4
Myh4
myosin, heavy polypeptide 4, skeletal muscle
chr12_-_81532840 0.46 ENSMUST00000169158.1
ENSMUST00000164431.1
ENSMUST00000163402.1
ENSMUST00000166664.1
ENSMUST00000164386.1
Synj2bp
Gm20498
synaptojanin 2 binding protein
predicted gene 20498
chr8_-_36732897 0.45 ENSMUST00000098826.3
Dlc1
deleted in liver cancer 1
chr9_-_44965519 0.45 ENSMUST00000125642.1
ENSMUST00000117506.1
ENSMUST00000117549.1
Ube4a
ubiquitination factor E4A, UFD2 homolog (S. cerevisiae)
chr4_-_82065889 0.45 ENSMUST00000143755.1
Gm11264
predicted gene 11264
chr2_+_59484645 0.45 ENSMUST00000028369.5
Dapl1
death associated protein-like 1
chr6_-_115251839 0.45 ENSMUST00000032462.6
Timp4
tissue inhibitor of metalloproteinase 4
chr7_+_62476306 0.45 ENSMUST00000097132.3
Atp5l-ps1
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit g, pseudogene 1
chr9_+_32372409 0.44 ENSMUST00000047334.8
Kcnj1
potassium inwardly-rectifying channel, subfamily J, member 1
chr7_+_26757153 0.42 ENSMUST00000077855.6
Cyp2b19
cytochrome P450, family 2, subfamily b, polypeptide 19
chr4_+_116720920 0.42 ENSMUST00000045542.6
ENSMUST00000106459.1
Tesk2
testis-specific kinase 2
chr5_-_38480131 0.41 ENSMUST00000143758.1
ENSMUST00000067886.5
Slc2a9
solute carrier family 2 (facilitated glucose transporter), member 9
chr10_+_116986314 0.41 ENSMUST00000020378.4
Best3
bestrophin 3
chr2_+_20737306 0.41 ENSMUST00000114606.1
ENSMUST00000114608.1
Etl4
enhancer trap locus 4
chr4_+_95579463 0.40 ENSMUST00000150830.1
ENSMUST00000134012.2
Fggy
FGGY carbohydrate kinase domain containing
chr6_-_112288837 0.40 ENSMUST00000053559.4
5031434C07Rik
RIKEN cDNA 5031434C07 gene
chr12_-_40445754 0.40 ENSMUST00000069692.8
ENSMUST00000069637.7
Zfp277
zinc finger protein 277
chr3_+_129199960 0.40 ENSMUST00000173645.2
Pitx2
paired-like homeodomain transcription factor 2
chr7_+_27653906 0.39 ENSMUST00000008088.7
Ttc9b
tetratricopeptide repeat domain 9B
chr11_-_84068554 0.39 ENSMUST00000164891.1
Dusp14
dual specificity phosphatase 14
chr10_-_95415283 0.39 ENSMUST00000119917.1
Socs2
suppressor of cytokine signaling 2
chr6_-_34910869 0.39 ENSMUST00000081214.5
Wdr91
WD repeat domain 91
chr7_+_125829653 0.38 ENSMUST00000124223.1
D430042O09Rik
RIKEN cDNA D430042O09 gene
chr11_-_120624973 0.38 ENSMUST00000106183.2
ENSMUST00000080202.5
Sirt7
sirtuin 7
chr5_+_102768771 0.38 ENSMUST00000112852.1
Arhgap24
Rho GTPase activating protein 24
chr2_+_33216051 0.38 ENSMUST00000004208.5
Angptl2
angiopoietin-like 2
chr6_-_129451906 0.38 ENSMUST00000037481.7
Clec1a
C-type lectin domain family 1, member a
chr6_+_90122643 0.37 ENSMUST00000174204.1
Vmn1r51
vomeronasal 1 receptor 51
chr10_-_58675631 0.37 ENSMUST00000003312.4
Edar
ectodysplasin-A receptor
chr16_-_59555752 0.37 ENSMUST00000179383.1
ENSMUST00000044604.8
Crybg3
beta-gamma crystallin domain containing 3
chr18_-_20114767 0.36 ENSMUST00000038710.5
Dsc1
desmocollin 1
chrX_-_141874870 0.36 ENSMUST00000182079.1
Gm15294
predicted gene 15294
chr10_+_24076500 0.36 ENSMUST00000051133.5
Taar8a
trace amine-associated receptor 8A
chr4_-_14621669 0.35 ENSMUST00000143105.1
Slc26a7
solute carrier family 26, member 7
chr1_-_52500679 0.35 ENSMUST00000069792.7
Nab1
Ngfi-A binding protein 1
chr5_+_24428208 0.35 ENSMUST00000115049.2
Slc4a2
solute carrier family 4 (anion exchanger), member 2
chr7_+_104329471 0.35 ENSMUST00000180136.1
ENSMUST00000178316.1
Trim34b
tripartite motif-containing 34B
chr19_+_56287911 0.35 ENSMUST00000095948.4
Habp2
hyaluronic acid binding protein 2
chr11_+_67200137 0.34 ENSMUST00000129018.1
Myh1
myosin, heavy polypeptide 1, skeletal muscle, adult
chr1_-_86111970 0.34 ENSMUST00000027431.6
Htr2b
5-hydroxytryptamine (serotonin) receptor 2B
chr11_+_115912001 0.33 ENSMUST00000132961.1
Smim6
small integral membrane protein 6
chr9_+_44101722 0.33 ENSMUST00000161703.1
ENSMUST00000161381.1
ENSMUST00000034654.7
Mfrp
membrane-type frizzled-related protein
chr2_-_37443096 0.33 ENSMUST00000102789.2
ENSMUST00000067043.4
ENSMUST00000112932.1
Zbtb26
Zbtb6
zinc finger and BTB domain containing 26
zinc finger and BTB domain containing 6
chr6_-_78378851 0.33 ENSMUST00000089667.1
ENSMUST00000167492.1
Reg3d
regenerating islet-derived 3 delta
chr8_+_58911755 0.33 ENSMUST00000062978.6
BC030500
cDNA sequence BC030500
chr10_+_59616063 0.33 ENSMUST00000095646.1
Gm10322
predicted gene 10322
chr19_+_56287943 0.32 ENSMUST00000166049.1
Habp2
hyaluronic acid binding protein 2
chrX_-_60147643 0.32 ENSMUST00000033478.4
ENSMUST00000101531.3
Mcf2
mcf.2 transforming sequence
chrX_-_155623325 0.31 ENSMUST00000038665.5
Ptchd1
patched domain containing 1
chr5_+_104775911 0.31 ENSMUST00000055593.7
Gm8258
predicted gene 8258
chr13_+_23695791 0.31 ENSMUST00000041052.2
Hist1h1t
histone cluster 1, H1t

Network of associatons between targets according to the STRING database.

First level regulatory network of Nfix

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:1903919 regulation of actin filament severing(GO:1903918) negative regulation of actin filament severing(GO:1903919)
0.6 2.6 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.6 1.9 GO:0006533 fumarate metabolic process(GO:0006106) aspartate biosynthetic process(GO:0006532) aspartate catabolic process(GO:0006533)
0.5 1.6 GO:0060300 regulation of cytokine activity(GO:0060300)
0.5 1.4 GO:0034971 histone H3-R17 methylation(GO:0034971)
0.5 1.4 GO:0051659 maintenance of mitochondrion location(GO:0051659)
0.5 3.7 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.4 0.9 GO:0003134 BMP signaling pathway involved in heart induction(GO:0003130) endodermal-mesodermal cell signaling(GO:0003133) endodermal-mesodermal cell signaling involved in heart induction(GO:0003134)
0.4 2.9 GO:0002003 angiotensin maturation(GO:0002003)
0.3 2.8 GO:0097460 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.3 1.0 GO:0003032 detection of oxygen(GO:0003032) cardiac jelly development(GO:1905072)
0.3 5.1 GO:0052695 cellular glucuronidation(GO:0052695)
0.3 0.8 GO:0001982 baroreceptor response to decreased systemic arterial blood pressure(GO:0001982)
0.3 0.6 GO:0046271 coumarin metabolic process(GO:0009804) phenylpropanoid catabolic process(GO:0046271)
0.3 1.4 GO:0009115 xanthine catabolic process(GO:0009115)
0.3 1.1 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.3 2.9 GO:0005513 detection of calcium ion(GO:0005513)
0.3 0.8 GO:0021759 globus pallidus development(GO:0021759)
0.3 0.8 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.3 1.5 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.2 0.7 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.2 0.9 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.2 0.7 GO:1900477 negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter(GO:1900477)
0.2 5.8 GO:0017144 drug metabolic process(GO:0017144)
0.2 8.6 GO:0010866 regulation of triglyceride biosynthetic process(GO:0010866)
0.2 1.1 GO:0072236 metanephric loop of Henle development(GO:0072236)
0.2 4.2 GO:0060134 prepulse inhibition(GO:0060134)
0.2 3.8 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.2 1.0 GO:1900425 negative regulation of defense response to bacterium(GO:1900425)
0.2 0.8 GO:0014028 notochord formation(GO:0014028) positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.2 1.2 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.2 3.6 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.2 0.6 GO:0050973 detection of mechanical stimulus involved in equilibrioception(GO:0050973)
0.2 0.9 GO:0050915 sensory perception of sour taste(GO:0050915)
0.2 0.5 GO:0021530 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.2 0.5 GO:0072198 mesenchymal cell proliferation involved in ureter development(GO:0072198) regulation of mesenchymal cell proliferation involved in ureter development(GO:0072199) positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.1 1.3 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1 1.1 GO:0015671 oxygen transport(GO:0015671)
0.1 1.1 GO:0006689 ganglioside catabolic process(GO:0006689)
0.1 0.7 GO:0007403 glial cell fate determination(GO:0007403)
0.1 1.6 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 0.3 GO:0007208 phospholipase C-activating serotonin receptor signaling pathway(GO:0007208)
0.1 1.5 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 4.2 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.1 0.5 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.1 1.1 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.1 0.4 GO:0045897 regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.1 1.1 GO:0010838 positive regulation of keratinocyte proliferation(GO:0010838) negative regulation of keratinocyte differentiation(GO:0045617)
0.1 0.5 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.1 0.6 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.1 0.3 GO:0021998 neural plate mediolateral regionalization(GO:0021998) mesoderm structural organization(GO:0048338) paraxial mesoderm structural organization(GO:0048352) positive regulation of cardiac ventricle development(GO:1904414)
0.1 0.5 GO:0035995 skeletal muscle myosin thick filament assembly(GO:0030241) detection of muscle stretch(GO:0035995)
0.1 0.2 GO:0021558 trochlear nerve development(GO:0021558)
0.1 0.2 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.1 0.6 GO:0045345 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343) positive regulation of MHC class I biosynthetic process(GO:0045345)
0.1 0.7 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
0.1 1.1 GO:0042407 cristae formation(GO:0042407)
0.1 0.6 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.1 1.4 GO:0021860 pyramidal neuron development(GO:0021860)
0.1 0.7 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.1 0.6 GO:1903207 neuron death in response to hydrogen peroxide(GO:0036476) regulation of hydrogen peroxide-induced neuron death(GO:1903207) negative regulation of hydrogen peroxide-induced neuron death(GO:1903208)
0.1 0.6 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.1 1.2 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.1 0.8 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 0.2 GO:1901475 pyruvate transmembrane transport(GO:1901475)
0.1 0.7 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.1 3.4 GO:0007520 myoblast fusion(GO:0007520)
0.1 2.5 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.1 0.5 GO:0019532 oxalate transport(GO:0019532)
0.1 0.2 GO:2000211 regulation of glutamate metabolic process(GO:2000211)
0.1 2.6 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 0.4 GO:0070294 renal sodium ion absorption(GO:0070294) regulation of inward rectifier potassium channel activity(GO:1901979)
0.1 0.2 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1 0.3 GO:0046618 drug export(GO:0046618)
0.0 0.1 GO:0046166 alditol catabolic process(GO:0019405) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.0 0.4 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0 0.2 GO:0061589 calcium activated phosphatidylserine scrambling(GO:0061589)
0.0 1.1 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.0 1.0 GO:0035641 locomotory exploration behavior(GO:0035641)
0.0 0.4 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.0 0.6 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.7 GO:0039694 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.0 0.6 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.4 GO:0046415 urate metabolic process(GO:0046415)
0.0 0.5 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 0.1 GO:0002587 negative regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002587)
0.0 0.2 GO:0061739 protein lipidation involved in autophagosome assembly(GO:0061739)
0.0 1.2 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.7 GO:2000010 positive regulation of protein localization to cell surface(GO:2000010)
0.0 0.2 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.6 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.7 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.0 0.6 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 0.1 GO:0045006 DNA deamination(GO:0045006)
0.0 0.1 GO:1903972 negative regulation of interleukin-6-mediated signaling pathway(GO:0070104) regulation of macrophage colony-stimulating factor signaling pathway(GO:1902226) regulation of response to macrophage colony-stimulating factor(GO:1903969) regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903972)
0.0 0.1 GO:0014719 skeletal muscle satellite cell activation(GO:0014719)
0.0 0.1 GO:0045829 negative regulation of isotype switching(GO:0045829) regulation of isotype switching to IgA isotypes(GO:0048296)
0.0 0.4 GO:0019321 pentose metabolic process(GO:0019321)
0.0 0.2 GO:0019896 axonal transport of mitochondrion(GO:0019896)
0.0 0.1 GO:0070350 white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350)
0.0 0.2 GO:0050957 equilibrioception(GO:0050957)
0.0 0.1 GO:0071211 protein targeting to vacuole involved in autophagy(GO:0071211) lysosomal membrane organization(GO:0097212) positive regulation of protein folding(GO:1903334)
0.0 0.3 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.0 0.9 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.5 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.3 GO:0033280 response to vitamin D(GO:0033280)
0.0 0.1 GO:1903564 regulation of protein localization to cilium(GO:1903564)
0.0 0.5 GO:0001502 cartilage condensation(GO:0001502)
0.0 0.3 GO:0014823 response to activity(GO:0014823)
0.0 0.2 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.0 0.8 GO:0006821 chloride transport(GO:0006821)
0.0 1.4 GO:0006695 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.0 0.2 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0 0.1 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.9 GO:0008333 endosome to lysosome transport(GO:0008333)
0.0 0.9 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.3 GO:0021794 thalamus development(GO:0021794)
0.0 0.1 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.0 0.2 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.1 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
0.0 0.7 GO:0007616 long-term memory(GO:0007616)
0.0 0.3 GO:0060080 inhibitory postsynaptic potential(GO:0060080)
0.0 0.1 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0 2.3 GO:0098656 anion transmembrane transport(GO:0098656)
0.0 0.1 GO:1900019 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.0 0.3 GO:0030204 chondroitin sulfate metabolic process(GO:0030204)
0.0 0.2 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.4 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 0.3 GO:0050912 detection of chemical stimulus involved in sensory perception of taste(GO:0050912)
0.0 0.2 GO:0060539 diaphragm development(GO:0060539)
0.0 0.1 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.6 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.3 GO:2000772 regulation of cellular senescence(GO:2000772)
0.0 0.8 GO:0046889 positive regulation of lipid biosynthetic process(GO:0046889)
0.0 0.1 GO:0060613 hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888) fat pad development(GO:0060613) positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
0.0 0.4 GO:0050907 detection of chemical stimulus involved in sensory perception(GO:0050907)
0.0 0.2 GO:0036158 outer dynein arm assembly(GO:0036158)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.9 GO:0031983 vesicle lumen(GO:0031983)
0.3 1.0 GO:0097209 epidermal lamellar body(GO:0097209)
0.3 2.8 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.2 1.2 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.2 1.2 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.2 2.9 GO:0031045 dense core granule(GO:0031045)
0.1 1.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 0.9 GO:0070695 FHF complex(GO:0070695)
0.1 1.1 GO:0061617 MICOS complex(GO:0061617)
0.1 3.6 GO:0045095 keratin filament(GO:0045095)
0.1 0.5 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.1 0.9 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.1 1.6 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 0.5 GO:0030478 actin cap(GO:0030478)
0.1 0.8 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 0.2 GO:0098842 postsynaptic early endosome(GO:0098842)
0.0 0.5 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.2 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.3 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.5 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.1 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.0 0.7 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 5.9 GO:0031227 intrinsic component of endoplasmic reticulum membrane(GO:0031227)
0.0 0.8 GO:0042588 zymogen granule(GO:0042588)
0.0 0.6 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.2 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.0 0.7 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.7 GO:0090568 nuclear transcriptional repressor complex(GO:0090568)
0.0 0.7 GO:0005922 connexon complex(GO:0005922)
0.0 1.2 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.2 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.0 0.9 GO:0001533 cornified envelope(GO:0001533)
0.0 0.6 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.3 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.2 GO:0005766 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 0.1 GO:0099522 lysosomal lumen(GO:0043202) region of cytosol(GO:0099522) postsynaptic cytosol(GO:0099524)
0.0 1.5 GO:0005811 lipid particle(GO:0005811)
0.0 0.2 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.1 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.8 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.2 GO:1904115 axon cytoplasm(GO:1904115)
0.0 0.4 GO:0030057 desmosome(GO:0030057)
0.0 0.1 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.7 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 0.8 GO:0032420 stereocilium(GO:0032420)
0.0 0.3 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.2 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.3 GO:0033270 paranode region of axon(GO:0033270)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.8 GO:0070287 ferritin receptor activity(GO:0070287)
0.7 2.9 GO:0030348 syntaxin-3 binding(GO:0030348)
0.6 2.6 GO:0032896 palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.6 1.9 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069) L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.5 1.5 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.4 2.6 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.4 1.2 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.3 1.1 GO:0004096 catalase activity(GO:0004096)
0.3 1.4 GO:0038181 bile acid receptor activity(GO:0038181)
0.3 1.4 GO:0016726 xanthine dehydrogenase activity(GO:0004854) oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor(GO:0016726)
0.3 0.8 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.2 0.7 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.2 1.1 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.2 1.3 GO:0004103 choline kinase activity(GO:0004103)
0.2 4.5 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.2 0.8 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.2 1.2 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.2 7.7 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.2 0.9 GO:0052794 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.2 0.6 GO:0004063 aryldialkylphosphatase activity(GO:0004063)
0.2 2.9 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.2 1.8 GO:0001594 trace-amine receptor activity(GO:0001594)
0.2 2.5 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.2 0.5 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.2 1.2 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.2 0.6 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.2 1.2 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.2 1.1 GO:0019864 IgG binding(GO:0019864)
0.1 0.7 GO:0038049 glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.1 0.6 GO:0086038 calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038)
0.1 1.5 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 0.9 GO:0019211 phosphatase activator activity(GO:0019211)
0.1 1.0 GO:0005534 galactose binding(GO:0005534)
0.1 4.8 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.1 0.4 GO:0019150 D-ribulokinase activity(GO:0019150)
0.1 0.6 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 2.9 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 0.7 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.1 0.5 GO:0051373 FATZ binding(GO:0051373)
0.1 0.7 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.1 0.4 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.1 5.7 GO:0005504 fatty acid binding(GO:0005504)
0.1 0.4 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1 0.9 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.1 0.2 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.1 0.6 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.1 0.3 GO:0031849 olfactory receptor binding(GO:0031849)
0.1 0.2 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.1 0.2 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.1 0.9 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 0.2 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.1 0.5 GO:0008527 taste receptor activity(GO:0008527)
0.1 0.8 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.0 0.7 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.2 GO:0032029 myosin tail binding(GO:0032029)
0.0 2.8 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.7 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.1 GO:0097677 STAT family protein binding(GO:0097677)
0.0 0.2 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 1.5 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.6 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.7 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 1.1 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.2 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.5 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.2 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.7 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.5 GO:0070513 death domain binding(GO:0070513)
0.0 0.3 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.3 GO:0051378 serotonin binding(GO:0051378)
0.0 0.6 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 4.7 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)
0.0 0.7 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.4 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.5 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.1 GO:0004947 bradykinin receptor activity(GO:0004947)
0.0 0.5 GO:0017166 vinculin binding(GO:0017166)
0.0 0.6 GO:0005542 folic acid binding(GO:0005542)
0.0 0.3 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.1 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 0.6 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.6 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.9 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.4 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.6 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.6 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.8 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.4 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.2 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.0 2.3 GO:0015293 symporter activity(GO:0015293)
0.0 1.6 GO:0019955 cytokine binding(GO:0019955)
0.0 0.5 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.6 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 0.2 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.1 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.2 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.8 GO:0097110 scaffold protein binding(GO:0097110)
0.0 1.1 GO:0032947 protein complex scaffold(GO:0032947)
0.0 0.2 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 2.2 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.5 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 1.1 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.1 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.2 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.1 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 0.2 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 3.5 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.1 1.5 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 2.9 PID BMP PATHWAY BMP receptor signaling
0.0 0.8 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.7 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 1.4 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 1.4 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.8 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.5 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 1.2 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.7 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.8 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 1.1 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.6 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 1.1 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.5 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 1.0 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.6 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.4 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.5 1.6 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.2 2.9 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.2 2.9 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.2 2.4 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.2 2.6 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 1.9 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 1.9 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 1.5 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 1.4 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 2.9 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 1.7 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 1.3 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 1.7 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.1 1.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 0.7 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0 0.7 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 1.0 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.6 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.8 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.6 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.4 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 1.6 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.7 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.3 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.7 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 1.2 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 1.5 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 0.5 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 1.1 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.9 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.3 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.9 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.6 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.6 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.5 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.2 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.7 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.6 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.1 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.3 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 1.5 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.0 1.0 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway