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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Mybl2

Z-value: 2.59

Motif logo

Transcription factors associated with Mybl2

Gene Symbol Gene ID Gene Info
ENSMUSG00000017861.5 myeloblastosis oncogene-like 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Mybl2mm10_v2_chr2_+_163054682_1630546930.895.7e-13Click!

Activity profile of Mybl2 motif

Sorted Z-values of Mybl2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_86078070 15.68 ENSMUST00000032069.5
adducin 2 (beta)
chr7_-_24760311 13.87 ENSMUST00000063956.5
CD177 antigen
chr3_+_51661167 13.07 ENSMUST00000099106.3
microsomal glutathione S-transferase 2
chr11_-_83286722 11.99 ENSMUST00000163961.2
schlafen family member 14
chr1_-_132390301 11.87 ENSMUST00000132435.1
transmembrane and coiled-coil domains 2
chr19_-_41802028 10.71 ENSMUST00000026150.8
ENSMUST00000177495.1
ENSMUST00000163265.1
Rho GTPase activating protein 19
chr2_+_84988194 9.55 ENSMUST00000028466.5
proteoglycan 3
chr1_-_169531343 9.52 ENSMUST00000028000.7
NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr5_-_24030297 8.98 ENSMUST00000101513.2
family with sequence similarity 126, member A
chr7_-_127137807 8.58 ENSMUST00000049931.5
sialophorin
chr2_+_25372315 8.08 ENSMUST00000028329.6
ENSMUST00000114293.2
ENSMUST00000100323.2
suppressor APC domain containing 2
chr4_-_124936852 7.85 ENSMUST00000030690.5
ENSMUST00000084296.3
cell division cycle associated 8
chr1_+_40439627 7.79 ENSMUST00000097772.3
interleukin 1 receptor-like 1
chr1_-_169531447 7.71 ENSMUST00000111368.1
NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr3_+_51661209 7.47 ENSMUST00000161590.1
microsomal glutathione S-transferase 2
chr3_-_36571952 7.27 ENSMUST00000029270.3
cyclin A2
chr19_-_15924560 7.17 ENSMUST00000162053.1
phosphoserine aminotransferase 1
chr6_+_113531675 7.13 ENSMUST00000036340.5
ENSMUST00000101051.2
Fanconi anemia, complementation group D2
chr18_+_34624621 6.94 ENSMUST00000167161.1
kinesin family member 20A
chr1_+_57995971 6.89 ENSMUST00000027202.8
shugoshin-like 2 (S. pombe)
chr2_+_29124106 6.85 ENSMUST00000129544.1
senataxin
chr14_-_67715585 6.79 ENSMUST00000163100.1
ENSMUST00000132705.1
ENSMUST00000124045.1
cell division cycle associated 2
chr11_-_116076986 6.66 ENSMUST00000153408.1
unc-13 homolog D (C. elegans)
chr13_-_23551648 6.19 ENSMUST00000102971.1
histone cluster 1, H4f
chr4_+_49059256 6.14 ENSMUST00000076670.2
RIKEN cDNA E130309F12 gene
chr7_-_4812351 5.82 ENSMUST00000079496.7
ubiquitin-conjugating enzyme E2S
chrX_-_143827391 5.68 ENSMUST00000087316.5
calpain 6
chr8_+_117498272 5.62 ENSMUST00000081232.7
phospholipase C, gamma 2
chr6_-_122609964 5.43 ENSMUST00000032211.4
growth differentiation factor 3
chr15_-_55090422 5.39 ENSMUST00000110231.1
ENSMUST00000023059.6
defective in sister chromatid cohesion 1 homolog (S. cerevisiae)
chr9_+_65890237 5.33 ENSMUST00000045802.6
RIKEN cDNA 2810417H13 gene
chr19_-_5726240 5.24 ENSMUST00000049295.8
ENSMUST00000075606.4
EH domain binding protein 1-like 1
chr14_-_87141206 5.17 ENSMUST00000022599.7
diaphanous homolog 3 (Drosophila)
chr6_-_39419967 5.01 ENSMUST00000122996.1
makorin, ring finger protein, 1
chr11_-_116077562 5.00 ENSMUST00000174822.1
unc-13 homolog D (C. elegans)
chr8_-_92355764 4.98 ENSMUST00000180102.1
ENSMUST00000179421.1
ENSMUST00000179222.1
ENSMUST00000179029.1
RIKEN cDNA 4933436C20 gene
chr11_+_58948890 4.87 ENSMUST00000078267.3
histone cluster 3, H2ba
chr13_-_59675754 4.80 ENSMUST00000022039.5
ENSMUST00000095739.2
golgi membrane protein 1
chr6_-_39419757 4.78 ENSMUST00000146785.1
ENSMUST00000114823.1
makorin, ring finger protein, 1
chr18_+_34625009 4.74 ENSMUST00000166044.1
kinesin family member 20A
chr2_+_13573927 4.63 ENSMUST00000141365.1
ENSMUST00000028062.2
vimentin
chr3_+_108739658 4.56 ENSMUST00000133931.2
AKNA domain containing 1
chr5_+_108132885 4.55 ENSMUST00000047677.7
coiled-coil domain containing 18
chr12_-_78906929 4.51 ENSMUST00000021544.7
pleckstrin 2
chr1_-_191575534 4.50 ENSMUST00000027933.5
denticleless homolog (Drosophila)
chr15_+_79891631 4.27 ENSMUST00000177350.1
ENSMUST00000177483.1
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3
chr11_-_4594750 4.21 ENSMUST00000109943.3
myotubularin related protein 3
chr14_-_89898466 4.04 ENSMUST00000081204.4
predicted gene 10110
chr7_-_30280335 4.03 ENSMUST00000108190.1
WD repeat domain 62
chrX_+_150547375 4.03 ENSMUST00000066337.6
ENSMUST00000112715.1
aminolevulinic acid synthase 2, erythroid
chr16_-_4003750 3.93 ENSMUST00000171658.1
ENSMUST00000171762.1
SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)
chr4_-_116627478 3.84 ENSMUST00000081182.4
ENSMUST00000030457.5
nuclear autoantigenic sperm protein (histone-binding)
chr13_-_49652714 3.82 ENSMUST00000021818.7
centromere protein P
chr1_+_191821444 3.82 ENSMUST00000027931.7
NIMA (never in mitosis gene a)-related expressed kinase 2
chr4_-_116627921 3.82 ENSMUST00000030456.7
nuclear autoantigenic sperm protein (histone-binding)
chr11_+_94990996 3.76 ENSMUST00000038696.5
protein phosphatase 1, regulatory subunit 9B
chr17_+_8924109 3.74 ENSMUST00000149440.1
phosphodiesterase 10A
chr5_+_34949435 3.68 ENSMUST00000030984.7
regulator of G-protein signaling 12
chr11_+_106751226 3.51 ENSMUST00000147326.2
ENSMUST00000182896.1
ENSMUST00000182908.1
ENSMUST00000086353.4
mast cell immunoglobulin like receptor 1
chr18_+_67800101 3.51 ENSMUST00000025425.5
centrosomal protein 192
chr14_+_44102654 3.41 ENSMUST00000074839.6
eosinophil-associated, ribonuclease A family, member 2
chr10_-_85102487 3.39 ENSMUST00000059383.6
four and a half LIM domains 4
chr8_+_83715504 3.36 ENSMUST00000109810.1
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39
chr8_-_80739497 3.35 ENSMUST00000043359.8
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
chr2_-_18998126 3.34 ENSMUST00000006912.5
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
chr4_+_99829437 3.33 ENSMUST00000124547.1
ENSMUST00000106994.1
EF-hand calcium binding domain 7
chr11_+_78346666 3.27 ENSMUST00000100755.3
unc-119 homolog (C. elegans)
chr13_-_4150628 3.27 ENSMUST00000110704.2
ENSMUST00000021635.7
aldo-keto reductase family 1, member C18
chr4_+_135626655 3.25 ENSMUST00000153347.1
RIKEN cDNA 1700029M20 gene
chr9_+_75071579 3.20 ENSMUST00000136731.1
myosin VA
chr14_-_43923368 3.15 ENSMUST00000163652.1
eosinophil-associated, ribonuclease A family, member 10
chr8_+_105827721 3.13 ENSMUST00000034365.4
translin-associated factor X (Tsnax) interacting protein 1
chr12_-_112829351 3.12 ENSMUST00000062092.5
cell division cycle associated 4
chr11_+_106276715 3.09 ENSMUST00000044462.3
testicular cell adhesion molecule 1
chr8_+_83608175 3.09 ENSMUST00000005620.8
DnaJ (Hsp40) homolog, subfamily B, member 1
chr4_+_130055010 3.08 ENSMUST00000123617.1
collagen, type XVI, alpha 1
chr12_+_111406809 3.04 ENSMUST00000150384.1
RIKEN cDNA A230065H16 gene
chr8_+_57488053 3.04 ENSMUST00000180690.1
RIKEN cDNA 2500002B13 gene
chr9_-_95750335 3.03 ENSMUST00000053785.3
transient receptor potential cation channel, subfamily C, member 1
chr11_+_106751255 2.99 ENSMUST00000183111.1
ENSMUST00000106794.2
mast cell immunoglobulin like receptor 1
chr5_+_76588663 2.97 ENSMUST00000121979.1
centrosomal protein 135
chr2_+_18998332 2.96 ENSMUST00000028069.1
RIKEN cDNA 4930426L09 gene
chr12_+_106010263 2.92 ENSMUST00000021539.8
ENSMUST00000085026.4
ENSMUST00000072040.5
vaccinia related kinase 1
chr13_-_55528511 2.91 ENSMUST00000047877.4
docking protein 3
chr19_+_33822908 2.87 ENSMUST00000042061.6
predicted pseudogene 5519
chr10_+_75954514 2.85 ENSMUST00000099577.3
predicted gene 5134
chr17_-_33718591 2.85 ENSMUST00000174040.1
ENSMUST00000173015.1
ENSMUST00000066121.6
ENSMUST00000172767.1
ENSMUST00000173329.1
membrane-associated ring finger (C3HC4) 2
chr10_+_128909866 2.82 ENSMUST00000026407.7
CD63 antigen
chr7_+_19577287 2.79 ENSMUST00000108453.1
zinc finger protein 296
chr14_-_54686060 2.78 ENSMUST00000125265.1
apoptotic chromatin condensation inducer 1
chr7_+_30280094 2.69 ENSMUST00000108187.1
ENSMUST00000014072.5
THAP domain containing 8
chr7_+_46861203 2.68 ENSMUST00000014545.4
lactate dehydrogenase C
chr11_+_29373618 2.66 ENSMUST00000040182.6
ENSMUST00000109477.1
coiled coil domain containing 88A
chr11_-_61342821 2.66 ENSMUST00000134423.1
ENSMUST00000093029.2
solute carrier family 47, member 2
chr19_+_34192229 2.62 ENSMUST00000054956.8
STAM binding protein like 1
chr11_+_69965396 2.62 ENSMUST00000018713.6
claudin 7
chr15_+_103240405 2.59 ENSMUST00000036004.9
ENSMUST00000087351.7
heterogeneous nuclear ribonucleoprotein A1
chr4_+_140906344 2.57 ENSMUST00000030765.6
peptidyl arginine deiminase, type II
chr4_-_126325672 2.57 ENSMUST00000102616.1
tektin 2
chr1_-_175688353 2.54 ENSMUST00000104984.1
choroideremia-like
chr13_-_47105790 2.53 ENSMUST00000129352.1
DEK oncogene (DNA binding)
chr4_+_100776664 2.47 ENSMUST00000030257.8
ENSMUST00000097955.2
cache domain containing 1
chr17_+_8849974 2.46 ENSMUST00000115720.1
phosphodiesterase 10A
chr7_-_10495322 2.42 ENSMUST00000032551.7
zinc finger protein interacting with K protein 1
chr17_+_35841668 2.41 ENSMUST00000174124.1
mediator of DNA damage checkpoint 1
chr5_-_149051300 2.39 ENSMUST00000110505.1
high mobility group box 1
chr2_-_73452666 2.37 ENSMUST00000151939.1
WAS/WASL interacting protein family, member 1
chr8_+_83715177 2.37 ENSMUST00000019576.8
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39
chr9_+_107554633 2.36 ENSMUST00000010211.4
Ras association (RalGDS/AF-6) domain family member 1
chr7_+_25627604 2.35 ENSMUST00000076034.6
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8
chr9_-_97111117 2.35 ENSMUST00000085206.4
solute carrier family 25, member 36
chr4_+_154237525 2.32 ENSMUST00000152159.1
multiple EGF-like-domains 6
chr5_-_112251137 2.31 ENSMUST00000112383.1
crystallin, beta A4
chr10_+_58446845 2.31 ENSMUST00000003310.5
RAN binding protein 2
chr14_+_65598546 2.27 ENSMUST00000150897.1
nuclear GTPase, germinal center associated
chr8_+_83715239 2.26 ENSMUST00000172396.1
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39
chr19_-_6128208 2.24 ENSMUST00000025702.7
sorting nexin 15
chr19_-_47919269 2.21 ENSMUST00000095998.5
inositol 1,4,5-triphosphate receptor interacting protein
chr19_-_8798495 2.20 ENSMUST00000096261.3
polymerase (RNA) II (DNA directed) polypeptide G
chr2_-_35336969 2.14 ENSMUST00000028241.6
stomatin
chrX_-_57338598 2.13 ENSMUST00000033468.4
ENSMUST00000114736.1
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr2_-_73453918 2.12 ENSMUST00000102679.1
WAS/WASL interacting protein family, member 1
chr3_+_90266507 2.07 ENSMUST00000098914.3
DENN/MADD domain containing 4B
chr4_+_127021311 2.07 ENSMUST00000030623.7
splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated)
chr3_-_69004475 2.05 ENSMUST00000154741.1
ENSMUST00000148031.1
intraflagellar transport 80
chr9_+_108826320 2.04 ENSMUST00000024238.5
cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila)
chr10_+_85102627 2.01 ENSMUST00000095383.4
expressed sequence AI597468
chr12_+_119260930 1.99 ENSMUST00000022467.9
predicted gene 6768
chr5_+_114774677 1.98 ENSMUST00000102578.4
ankyrin repeat domain 13a
chrX_-_157492280 1.98 ENSMUST00000112529.1
spermine synthase
chr8_-_40634750 1.96 ENSMUST00000173957.1
myotubularin related protein 7
chr11_-_98729374 1.96 ENSMUST00000126565.1
ENSMUST00000100500.2
ENSMUST00000017354.6
mediator complex subunit 24
chr9_+_14784638 1.95 ENSMUST00000034405.4
meiotic recombination 11 homolog A (S. cerevisiae)
chr17_+_34398802 1.95 ENSMUST00000114175.1
ENSMUST00000078615.5
ENSMUST00000139063.1
ENSMUST00000097348.2
cDNA sequence BC051142
chr10_-_100589205 1.94 ENSMUST00000054471.8
RIKEN cDNA 4930430F08 gene
chr2_+_121506748 1.92 ENSMUST00000099473.3
ENSMUST00000110602.2
WD repeat domain 76
chr12_+_99884498 1.89 ENSMUST00000153627.1
tyrosyl-DNA phosphodiesterase 1
chr7_-_28598140 1.89 ENSMUST00000040531.8
ENSMUST00000108283.1
sterile alpha motif domain containing 4B
p21 protein (Cdc42/Rac)-activated kinase 4
chr15_-_36608959 1.88 ENSMUST00000001809.8
poly(A) binding protein, cytoplasmic 1
chr4_+_62525369 1.86 ENSMUST00000062145.1
RIKEN cDNA 4933430I17 gene
chr2_+_155956537 1.85 ENSMUST00000109619.2
ENSMUST00000039994.7
ENSMUST00000094421.4
ENSMUST00000151569.1
ENSMUST00000109618.1
centrosomal protein 250
chr11_+_3332426 1.80 ENSMUST00000136474.1
phosphoinositide-3-kinase interacting protein 1
chr17_+_5492558 1.80 ENSMUST00000089185.4
zinc finger, DHHC domain containing 14
chr4_-_107810948 1.76 ENSMUST00000097930.1
RIKEN cDNA B230314M03 gene
chr9_+_14784660 1.74 ENSMUST00000115632.3
ENSMUST00000147305.1
meiotic recombination 11 homolog A (S. cerevisiae)
chr14_+_75284343 1.67 ENSMUST00000022577.5
zinc finger CCCH type containing 13
chr19_-_6128144 1.66 ENSMUST00000154601.1
ENSMUST00000138931.1
sorting nexin 15
chr6_-_47594967 1.64 ENSMUST00000081721.6
ENSMUST00000114618.1
ENSMUST00000114616.1
enhancer of zeste homolog 2 (Drosophila)
chrX_-_139714481 1.64 ENSMUST00000183728.1
predicted gene 15013
chr6_+_125145235 1.63 ENSMUST00000119527.1
ENSMUST00000088276.6
ENSMUST00000051171.7
ENSMUST00000117675.1
intermediate filament family orphan 1
chr7_+_25681158 1.61 ENSMUST00000108403.3
B9 protein domain 2
chr3_+_116594959 1.61 ENSMUST00000029571.8
spindle assembly 6 homolog (C. elegans)
chrX_+_138914422 1.61 ENSMUST00000064937.7
ENSMUST00000113052.1
Nik related kinase
chr13_+_51645232 1.60 ENSMUST00000075853.5
CDC28 protein kinase regulatory subunit 2
chr15_-_80083374 1.59 ENSMUST00000081650.7
ribosomal protein L3
chr9_+_96119362 1.58 ENSMUST00000085217.5
ENSMUST00000122383.1
glycerol kinase 5 (putative)
chr3_-_130730375 1.55 ENSMUST00000079085.6
ribosomal protein L34
chr7_+_121083322 1.54 ENSMUST00000047025.8
ENSMUST00000170106.1
otoancorin
chr7_+_102065713 1.52 ENSMUST00000094129.2
ENSMUST00000094130.2
ENSMUST00000084843.3
transient receptor potential cation channel, subfamily C, member 2
chr18_+_14706145 1.50 ENSMUST00000040860.1
proteasome (prosome, macropain) subunit, alpha type, 8
chr19_+_53142756 1.50 ENSMUST00000050096.7
adducin 3 (gamma)
chr14_+_67716095 1.49 ENSMUST00000078053.6
ENSMUST00000145542.1
ENSMUST00000125212.1
potassium channel tetramerisation domain containing 9
chr3_-_95995698 1.46 ENSMUST00000130043.1
pleckstrin homology domain containing, family O member 1
chr6_-_113600645 1.45 ENSMUST00000035870.4
Fancd2 opposite strand
chrY_+_90755657 1.44 ENSMUST00000167967.2
predicted gene, 21857
chr4_-_136021722 1.44 ENSMUST00000030427.5
transcription elongation factor B (SIII), polypeptide 3
chr6_+_57702601 1.43 ENSMUST00000072954.1
ENSMUST00000050077.8
LanC (bacterial lantibiotic synthetase component C)-like 2
chr7_-_35537677 1.43 ENSMUST00000127472.1
ENSMUST00000032701.7
tudor domain containing 12
chr8_-_94037007 1.43 ENSMUST00000034204.9
nudix (nucleoside diphosphate linked moiety X)-type motif 21
chr3_-_69004565 1.42 ENSMUST00000169064.1
intraflagellar transport 80
chr9_-_45984816 1.42 ENSMUST00000172450.1
platelet-activating factor acetylhydrolase, isoform 1b, subunit 2
chr19_-_53464721 1.41 ENSMUST00000180489.1
RIKEN cDNA 5830416P10 gene
chr10_+_69534039 1.41 ENSMUST00000182557.1
ankyrin 3, epithelial
chr7_+_46847128 1.40 ENSMUST00000005051.4
lactate dehydrogenase A
chr4_-_88676924 1.39 ENSMUST00000105148.1
predicted gene 13280
chr3_-_130730310 1.35 ENSMUST00000062601.7
ribosomal protein L34
chr15_+_59374198 1.35 ENSMUST00000079703.3
ENSMUST00000168722.1
non-SMC element 2 homolog (MMS21, S. cerevisiae)
chr8_+_70234613 1.31 ENSMUST00000145078.1
SURP and G patch domain containing 2
chr8_-_69184177 1.28 ENSMUST00000185176.1
leucine zipper, putative tumor suppressor 1
chr18_-_34624562 1.28 ENSMUST00000003876.3
ENSMUST00000115766.1
ENSMUST00000097626.3
ENSMUST00000115765.1
bromodomain containing 8
chr19_-_5366285 1.27 ENSMUST00000170010.1
barrier to autointegration factor 1
chr12_-_55821157 1.27 ENSMUST00000110687.1
ENSMUST00000085385.5
Ral GTPase activating protein, alpha subunit 1
chr8_-_69791170 1.26 ENSMUST00000131784.1
zinc finger protein 866
chr17_-_57011271 1.25 ENSMUST00000002733.6
general transcription factor IIF, polypeptide 1
chr13_+_95325195 1.24 ENSMUST00000045909.7
zinc finger, BED domain containing 3
chr3_-_69004503 1.22 ENSMUST00000107812.1
intraflagellar transport 80
chr7_-_139978709 1.20 ENSMUST00000121412.1
RIKEN cDNA 6430531B16 gene
chr2_-_120731503 1.19 ENSMUST00000110701.1
ENSMUST00000110700.1
congenital dyserythropoietic anemia, type I (human)
chr16_+_14163275 1.19 ENSMUST00000023359.6
ENSMUST00000117958.1
nuclear distribution gene E homolog 1 (A nidulans)
chr5_-_122372230 1.19 ENSMUST00000031419.5
family with sequence similarity 216, member A
chr3_-_95995999 1.18 ENSMUST00000015889.3
pleckstrin homology domain containing, family O member 1
chr3_-_95995835 1.18 ENSMUST00000143485.1
pleckstrin homology domain containing, family O member 1
chrX_-_57393020 1.16 ENSMUST00000143310.1
ENSMUST00000098470.2
ENSMUST00000114726.1
RNA binding motif protein, X chromosome
chr7_+_102065485 1.16 ENSMUST00000106950.1
ENSMUST00000146450.1
transient receptor potential cation channel, subfamily C, member 2
chr17_+_35841491 1.16 ENSMUST00000082337.6
mediator of DNA damage checkpoint 1
chr5_-_149053038 1.15 ENSMUST00000085546.6
high mobility group box 1
chr4_-_115133977 1.14 ENSMUST00000051400.7
cytochrome P450, family 4, subfamily x, polypeptide 1
chr14_+_31001383 1.14 ENSMUST00000168584.1
glycosyltransferase 8 domain containing 1
chr15_-_55072139 1.13 ENSMUST00000041733.7
TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr8_-_107439585 1.12 ENSMUST00000077208.4
ribosomal protein S26, pseudogene 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Mybl2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 8.6 GO:0002884 regulation of type IV hypersensitivity(GO:0001807) negative regulation of acute inflammatory response to antigenic stimulus(GO:0002865) negative regulation of hypersensitivity(GO:0002884)
2.4 9.5 GO:0045575 basophil activation(GO:0045575)
2.3 6.9 GO:0031554 regulation of DNA-templated transcription, termination(GO:0031554)
1.5 5.8 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
1.4 7.2 GO:0006564 L-serine biosynthetic process(GO:0006564)
1.4 5.7 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
1.3 3.9 GO:1904431 positive regulation of t-circle formation(GO:1904431)
1.3 11.7 GO:0002432 granuloma formation(GO:0002432)
1.3 3.8 GO:2000474 regulation of opioid receptor signaling pathway(GO:2000474)
1.2 3.5 GO:0002270 plasmacytoid dendritic cell activation(GO:0002270)
1.1 5.6 GO:0032237 activation of store-operated calcium channel activity(GO:0032237)
1.1 3.3 GO:0071395 sesquiterpenoid metabolic process(GO:0006714) response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
1.1 5.4 GO:0034421 post-translational protein acetylation(GO:0034421)
1.0 7.1 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.9 20.5 GO:0019370 leukotriene biosynthetic process(GO:0019370)
0.9 4.6 GO:1900147 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.9 5.6 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.8 3.3 GO:2001287 negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.8 3.2 GO:0051643 endoplasmic reticulum localization(GO:0051643)
0.8 2.4 GO:0019043 establishment of viral latency(GO:0019043)
0.8 2.3 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.7 3.7 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.7 3.7 GO:0038032 termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.7 7.8 GO:0002826 negative regulation of T-helper 1 type immune response(GO:0002826)
0.7 12.0 GO:0016075 rRNA catabolic process(GO:0016075)
0.7 2.0 GO:0006597 spermine biosynthetic process(GO:0006597)
0.6 2.6 GO:2000402 negative regulation of lymphocyte migration(GO:2000402)
0.6 11.7 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.6 1.8 GO:2000409 positive regulation of T cell extravasation(GO:2000409)
0.6 2.4 GO:0030311 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.6 2.9 GO:0035405 histone-threonine phosphorylation(GO:0035405) histone H3-S10 phosphorylation(GO:0043987)
0.6 15.7 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.6 2.8 GO:2000680 regulation of rubidium ion transport(GO:2000680)
0.5 1.6 GO:0071707 immunoglobulin heavy chain V-D-J recombination(GO:0071707)
0.5 5.4 GO:0048859 formation of anatomical boundary(GO:0048859)
0.5 2.7 GO:0019516 lactate oxidation(GO:0019516)
0.5 2.7 GO:0002121 inter-male aggressive behavior(GO:0002121)
0.5 1.6 GO:0060722 spongiotrophoblast cell proliferation(GO:0060720) cell proliferation involved in embryonic placenta development(GO:0060722)
0.5 2.7 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.5 13.8 GO:0006336 DNA replication-independent nucleosome assembly(GO:0006336)
0.5 3.4 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.5 2.4 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.4 16.3 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.4 1.3 GO:0070676 intralumenal vesicle formation(GO:0070676) negative regulation of early endosome to late endosome transport(GO:2000642)
0.4 4.7 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.4 3.4 GO:0016584 nucleosome positioning(GO:0016584)
0.4 8.6 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.4 6.5 GO:0033004 negative regulation of mast cell activation(GO:0033004)
0.4 2.8 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.4 12.1 GO:0007099 centriole replication(GO:0007099)
0.4 1.9 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.4 3.3 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.4 2.5 GO:0044838 cell quiescence(GO:0044838) regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.4 1.4 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.3 4.5 GO:0019985 translesion synthesis(GO:0019985)
0.3 2.1 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.3 6.2 GO:0046069 cGMP catabolic process(GO:0046069)
0.3 2.0 GO:0036515 serotonergic neuron axon guidance(GO:0036515)
0.3 1.0 GO:0052203 modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.3 0.9 GO:0006713 glucocorticoid catabolic process(GO:0006713)
0.3 4.3 GO:0010529 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
0.3 4.8 GO:0051451 myoblast migration(GO:0051451)
0.3 1.4 GO:0019244 lactate biosynthetic process from pyruvate(GO:0019244)
0.3 2.1 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.3 9.0 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.3 1.0 GO:2000321 positive regulation of T-helper 17 cell differentiation(GO:2000321)
0.3 1.8 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.3 4.0 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.2 1.2 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.2 2.2 GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291)
0.2 1.7 GO:0021776 smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.2 1.0 GO:0035582 sequestering of BMP in extracellular matrix(GO:0035582)
0.2 0.9 GO:0002188 translation reinitiation(GO:0002188)
0.2 0.6 GO:0019389 glucuronoside metabolic process(GO:0019389)
0.2 2.9 GO:1904659 glucose transmembrane transport(GO:1904659)
0.2 3.0 GO:0046541 saliva secretion(GO:0046541)
0.2 0.8 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.2 2.3 GO:0048757 endosome to melanosome transport(GO:0035646) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757)
0.2 2.3 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.2 3.1 GO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
0.2 11.9 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.2 2.6 GO:0036159 inner dynein arm assembly(GO:0036159)
0.2 0.9 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.2 2.7 GO:0006855 drug transmembrane transport(GO:0006855)
0.2 1.8 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.2 0.5 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.2 1.4 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.2 1.6 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.2 6.4 GO:0016572 histone phosphorylation(GO:0016572)
0.2 0.5 GO:0043686 co-translational protein modification(GO:0043686)
0.1 8.5 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.1 1.9 GO:0000012 single strand break repair(GO:0000012)
0.1 5.7 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.1 0.4 GO:0070948 regulation of neutrophil mediated cytotoxicity(GO:0070948) regulation of neutrophil mediated killing of symbiont cell(GO:0070949)
0.1 0.6 GO:0010641 positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641)
0.1 1.1 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.1 1.2 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.1 0.9 GO:0051409 response to nitrosative stress(GO:0051409)
0.1 0.9 GO:1902570 protein localization to nucleolus(GO:1902570)
0.1 4.5 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.1 0.8 GO:0045583 regulation of cytotoxic T cell differentiation(GO:0045583) positive regulation of cytotoxic T cell differentiation(GO:0045585)
0.1 2.4 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.1 2.2 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 0.9 GO:0016266 O-glycan processing(GO:0016266)
0.1 0.5 GO:0000393 spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
0.1 0.8 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.1 0.4 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
0.1 0.5 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.1 0.4 GO:1990022 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.1 3.1 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894)
0.1 1.9 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.1 0.8 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.1 0.3 GO:0042275 error-free postreplication DNA repair(GO:0042275)
0.1 1.4 GO:0034587 piRNA metabolic process(GO:0034587)
0.1 0.6 GO:0048549 endosome localization(GO:0032439) positive regulation of pinocytosis(GO:0048549) Golgi to lysosome transport(GO:0090160)
0.1 5.2 GO:0035307 positive regulation of protein dephosphorylation(GO:0035307)
0.1 0.7 GO:1900034 regulation of cellular response to heat(GO:1900034)
0.1 0.8 GO:0035879 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.1 1.6 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 1.0 GO:1900037 regulation of cellular response to hypoxia(GO:1900037)
0.1 0.3 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.1 0.5 GO:0071397 cellular response to cholesterol(GO:0071397)
0.1 1.2 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.1 0.9 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.1 0.3 GO:0015074 DNA integration(GO:0015074)
0.1 0.4 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.1 1.6 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.1 1.9 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.1 9.3 GO:1990830 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.1 1.7 GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
0.1 4.4 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.1 1.4 GO:0006379 mRNA cleavage(GO:0006379)
0.0 4.2 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.9 GO:0045070 positive regulation of viral genome replication(GO:0045070)
0.0 0.5 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 1.8 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 0.3 GO:0031053 primary miRNA processing(GO:0031053)
0.0 4.5 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 0.6 GO:0002070 epithelial cell maturation(GO:0002070)
0.0 0.2 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0 0.7 GO:2000637 positive regulation of gene silencing by miRNA(GO:2000637)
0.0 0.8 GO:0006907 pinocytosis(GO:0006907)
0.0 0.2 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.5 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.2 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.0 0.1 GO:0090365 regulation of mRNA modification(GO:0090365)
0.0 1.4 GO:0016239 positive regulation of macroautophagy(GO:0016239)
0.0 1.0 GO:0048741 skeletal muscle fiber development(GO:0048741)
0.0 0.6 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.0 2.5 GO:0031497 chromatin assembly(GO:0031497)
0.0 0.3 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)
0.0 1.0 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 1.5 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.3 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.8 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.0 0.1 GO:0021886 hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888)
0.0 0.3 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 1.8 GO:0006997 nucleus organization(GO:0006997)
0.0 0.5 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 0.6 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.1 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 2.3 GO:0007601 visual perception(GO:0007601)
0.0 2.5 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.0 0.5 GO:0016445 somatic diversification of immunoglobulins(GO:0016445)
0.0 0.5 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.4 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 18.1 GO:0031262 Ndc80 complex(GO:0031262)
1.6 15.7 GO:0008290 F-actin capping protein complex(GO:0008290)
1.3 7.9 GO:0032133 chromosome passenger complex(GO:0032133)
1.1 3.2 GO:0042642 actomyosin, myosin complex part(GO:0042642)
1.1 11.7 GO:0033093 Weibel-Palade body(GO:0033093)
1.0 8.0 GO:0001940 male pronucleus(GO:0001940)
0.8 3.9 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.8 3.1 GO:0099524 region of cytosol(GO:0099522) postsynaptic cytosol(GO:0099524)
0.7 5.0 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.7 2.8 GO:0032585 multivesicular body membrane(GO:0032585) multivesicular body, internal vesicle(GO:0097487)
0.7 4.8 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.7 8.6 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.6 3.7 GO:0030870 Mre11 complex(GO:0030870)
0.6 5.4 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.6 6.5 GO:0042629 mast cell granule(GO:0042629)
0.6 4.6 GO:0045098 type III intermediate filament(GO:0045098)
0.4 3.5 GO:0042382 paraspeckles(GO:0042382)
0.4 3.8 GO:0032591 dendritic spine membrane(GO:0032591) dendritic spine neck(GO:0044326)
0.3 3.4 GO:0005677 chromatin silencing complex(GO:0005677)
0.3 0.9 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.3 1.5 GO:1990111 spermatoproteasome complex(GO:1990111)
0.3 1.8 GO:0044530 supraspliceosomal complex(GO:0044530)
0.3 1.4 GO:1990923 PET complex(GO:1990923)
0.3 2.5 GO:0061574 ASAP complex(GO:0061574)
0.3 1.6 GO:0098536 deuterosome(GO:0098536)
0.2 5.1 GO:0005682 U5 snRNP(GO:0005682)
0.2 5.1 GO:0005680 anaphase-promoting complex(GO:0005680)
0.2 2.2 GO:0000812 Swr1 complex(GO:0000812)
0.2 1.3 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.2 12.9 GO:0005871 kinesin complex(GO:0005871)
0.2 5.4 GO:0030992 intraciliary transport particle B(GO:0030992)
0.2 4.1 GO:0000242 pericentriolar material(GO:0000242)
0.2 6.1 GO:0000788 nuclear nucleosome(GO:0000788)
0.2 0.5 GO:0071001 U4/U6 snRNP(GO:0071001)
0.2 0.9 GO:0000125 PCAF complex(GO:0000125)
0.2 0.8 GO:0097226 sperm mitochondrial sheath(GO:0097226)
0.1 1.0 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.1 7.9 GO:0045171 intercellular bridge(GO:0045171)
0.1 2.1 GO:0036038 MKS complex(GO:0036038)
0.1 1.9 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 5.7 GO:0005876 spindle microtubule(GO:0005876)
0.1 0.8 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.1 0.9 GO:0030896 checkpoint clamp complex(GO:0030896)
0.1 2.6 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 2.2 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 1.9 GO:0097526 spliceosomal tri-snRNP complex(GO:0097526)
0.1 4.9 GO:0000786 nucleosome(GO:0000786)
0.1 0.8 GO:0097422 tubular endosome(GO:0097422)
0.1 2.6 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.9 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.1 2.2 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 5.6 GO:0043034 costamere(GO:0043034)
0.1 1.8 GO:0045120 pronucleus(GO:0045120)
0.1 0.9 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1 0.3 GO:0070877 microprocessor complex(GO:0070877) ribonuclease III complex(GO:1903095)
0.1 0.3 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.1 3.7 GO:0097440 apical dendrite(GO:0097440)
0.1 3.7 GO:0016592 mediator complex(GO:0016592)
0.1 0.9 GO:0071141 SMAD protein complex(GO:0071141)
0.1 1.7 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 1.7 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.1 12.5 GO:0000793 condensed chromosome(GO:0000793)
0.1 1.1 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.1 0.6 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.1 2.7 GO:0032590 dendrite membrane(GO:0032590)
0.1 0.9 GO:0000974 Prp19 complex(GO:0000974)
0.1 0.7 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.1 5.6 GO:0005814 centriole(GO:0005814)
0.1 0.3 GO:1990130 Iml1 complex(GO:1990130)
0.1 11.5 GO:0031225 anchored component of membrane(GO:0031225)
0.1 1.0 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.1 4.5 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 0.7 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.1 1.3 GO:0030904 retromer complex(GO:0030904)
0.0 0.5 GO:0005869 dynactin complex(GO:0005869)
0.0 7.2 GO:0005681 spliceosomal complex(GO:0005681)
0.0 1.3 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.3 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 1.6 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 1.5 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.5 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.3 GO:0070761 pre-snoRNP complex(GO:0070761)
0.0 2.9 GO:0005795 Golgi stack(GO:0005795)
0.0 0.2 GO:0061617 MICOS complex(GO:0061617)
0.0 11.7 GO:0005635 nuclear envelope(GO:0005635)
0.0 0.8 GO:0032040 small-subunit processome(GO:0032040)
0.0 3.2 GO:0000775 chromosome, centromeric region(GO:0000775)
0.0 0.9 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 2.2 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 1.5 GO:0005776 autophagosome(GO:0005776)
0.0 1.7 GO:0005882 intermediate filament(GO:0005882)
0.0 1.9 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.5 GO:0002080 acrosomal membrane(GO:0002080)
0.0 1.3 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.9 GO:0016459 myosin complex(GO:0016459)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
5.1 20.5 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
2.6 7.8 GO:0002113 interleukin-33 binding(GO:0002113)
2.3 6.9 GO:0001147 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
1.3 4.0 GO:0016748 succinyltransferase activity(GO:0016748)
1.2 3.5 GO:0000401 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)
1.1 3.3 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
1.1 3.3 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006) delta4-3-oxosteroid 5beta-reductase activity(GO:0047787)
1.1 4.3 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
0.9 4.6 GO:1990254 keratin filament binding(GO:1990254)
0.9 6.2 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.8 3.9 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.8 2.4 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.6 1.9 GO:0001129 RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132)
0.6 4.1 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.5 4.2 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.5 2.6 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.5 5.4 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.5 2.9 GO:0035184 nucleosomal histone binding(GO:0031493) histone threonine kinase activity(GO:0035184)
0.5 1.4 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.4 1.8 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.4 0.9 GO:0001034 RNA polymerase III transcription factor activity, sequence-specific DNA binding(GO:0001034)
0.4 5.7 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.4 1.6 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.3 3.8 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.3 0.9 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.3 0.9 GO:0035500 MH2 domain binding(GO:0035500)
0.3 1.4 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.3 7.2 GO:0008483 transaminase activity(GO:0008483)
0.3 3.7 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.2 17.0 GO:0030507 spectrin binding(GO:0030507)
0.2 2.9 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.2 1.6 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.2 5.7 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.2 5.7 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.2 6.4 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.2 0.8 GO:0002135 CTP binding(GO:0002135)
0.2 2.7 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.2 10.7 GO:0004521 endoribonuclease activity(GO:0004521)
0.2 0.9 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.2 1.3 GO:0019211 phosphatase activator activity(GO:0019211)
0.2 0.5 GO:0004637 phosphoribosylamine-glycine ligase activity(GO:0004637)
0.2 3.2 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.2 0.5 GO:0030621 U4 snRNA binding(GO:0030621)
0.2 1.4 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.2 0.8 GO:0034452 dynactin binding(GO:0034452)
0.2 0.9 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.2 1.4 GO:1990446 U1 snRNP binding(GO:1990446)
0.1 0.9 GO:0042731 PH domain binding(GO:0042731)
0.1 0.6 GO:0034511 U3 snoRNA binding(GO:0034511)
0.1 0.4 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1 8.1 GO:0030544 Hsp70 protein binding(GO:0030544)
0.1 7.3 GO:0097472 cyclin-dependent protein kinase activity(GO:0097472)
0.1 6.1 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 1.0 GO:0001849 complement component C1q binding(GO:0001849)
0.1 0.8 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 11.7 GO:0003777 microtubule motor activity(GO:0003777)
0.1 3.7 GO:0019789 SUMO transferase activity(GO:0019789)
0.1 2.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.7 GO:0033592 RNA strand annealing activity(GO:0033592)
0.1 2.5 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.1 6.6 GO:0004540 ribonuclease activity(GO:0004540)
0.1 7.7 GO:0004004 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.1 2.0 GO:0008266 poly(U) RNA binding(GO:0008266)
0.1 0.6 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.1 5.4 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.1 1.9 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 2.4 GO:0015215 nucleotide transmembrane transporter activity(GO:0015215)
0.1 17.6 GO:0042393 histone binding(GO:0042393)
0.1 0.9 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.1 0.9 GO:0008097 5S rRNA binding(GO:0008097)
0.1 0.4 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.1 2.4 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 1.5 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 0.2 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.1 1.2 GO:0070182 DNA polymerase binding(GO:0070182)
0.1 1.0 GO:0035497 cAMP response element binding(GO:0035497)
0.1 2.9 GO:0005158 insulin receptor binding(GO:0005158)
0.1 0.2 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 0.3 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.0 4.7 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.8 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.3 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.0 6.6 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 1.6 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 2.1 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.9 GO:0004697 protein kinase C activity(GO:0004697)
0.0 1.4 GO:0017091 AU-rich element binding(GO:0017091)
0.0 5.2 GO:0005178 integrin binding(GO:0005178)
0.0 1.3 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.1 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.0 1.0 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.5 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.9 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.9 GO:0097602 cullin family protein binding(GO:0097602)
0.0 1.2 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.4 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.5 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.5 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.8 GO:0015238 drug transmembrane transporter activity(GO:0015238)
0.0 6.9 GO:0019902 phosphatase binding(GO:0019902)
0.0 8.4 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 0.5 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.8 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.5 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.2 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 1.3 GO:0070063 RNA polymerase binding(GO:0070063)
0.0 1.4 GO:0004386 helicase activity(GO:0004386)
0.0 3.9 GO:0017124 SH3 domain binding(GO:0017124)
0.0 2.1 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0 0.6 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.9 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.3 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.9 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 4.5 GO:0030695 GTPase regulator activity(GO:0030695)
0.0 0.8 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.9 GO:0003774 motor activity(GO:0003774)
0.0 2.0 GO:0001076 transcription factor activity, RNA polymerase II transcription factor binding(GO:0001076)
0.0 6.8 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 0.8 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.0 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.3 GO:0070330 aromatase activity(GO:0070330)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 8.6 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.5 24.2 PID AURORA B PATHWAY Aurora B signaling
0.5 7.3 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.4 15.2 PID ATM PATHWAY ATM pathway
0.2 9.5 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 2.3 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 3.5 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 5.1 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.1 3.8 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.1 1.6 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 1.9 PID MYC PATHWAY C-MYC pathway
0.0 2.3 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.8 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.4 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 1.9 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.0 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.9 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 2.5 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 9.2 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.9 PID RHOA PATHWAY RhoA signaling pathway
0.0 1.5 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 2.0 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.9 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.8 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.8 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.7 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.7 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.8 PID RAC1 REG PATHWAY Regulation of RAC1 activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 7.1 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.5 19.7 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.5 7.3 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.4 11.7 REACTOME KINESINS Genes involved in Kinesins
0.4 7.3 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.4 40.6 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.3 2.4 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.3 9.4 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.3 7.2 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.3 10.7 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.2 2.7 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.2 3.5 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.2 3.5 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.2 3.1 REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.2 2.5 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.2 4.0 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.2 6.2 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.2 1.9 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.1 7.5 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 5.6 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.1 2.2 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.1 1.9 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 3.0 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.1 2.0 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 1.4 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.1 7.6 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.1 2.0 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 4.6 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 1.0 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 1.1 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.1 1.2 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.1 1.9 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 12.7 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 0.9 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 2.6 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 3.2 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.1 5.6 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.9 REACTOME RNA POL II PRE TRANSCRIPTION EVENTS Genes involved in RNA Polymerase II Pre-transcription Events
0.0 5.4 REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION Genes involved in 3' -UTR-mediated translational regulation
0.0 10.0 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.5 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0 0.3 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 1.9 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 1.0 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.7 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 1.3 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.9 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress
0.0 0.5 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 2.0 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 3.0 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.0 0.6 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport