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avrg: GSE58827: Dynamics of the Mouse Liver
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Results for Egr4
Z-value: 0.50
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Transcription factors associated with Egr4
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Egr4 | mm10_v2_chr6_-_85513586_85513591 | -0.26 | 1.3e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chrX_+_49470555 Show fit | 0.77 |
ENSMUST00000042444.6
|
Rho GTPase activating protein 36 |
|
| chrX_+_49470450 Show fit | 0.76 |
ENSMUST00000114904.3
|
Rho GTPase activating protein 36 |
|
| chr11_-_53470479 Show fit | 0.51 |
ENSMUST00000057722.2
|
predicted gene 9837 |
|
| chr4_-_43046196 Show fit | 0.45 |
ENSMUST00000036462.5
|
family with sequence similarity 214, member B |
|
| chr8_-_92356103 Show fit | 0.40 |
ENSMUST00000034183.3
|
RIKEN cDNA 4933436C20 gene |
|
| chr6_+_127149389 Show fit | 0.36 |
ENSMUST00000180811.1
|
RIKEN cDNA 9330179D12 gene |
|
| chr12_+_76370266 Show fit | 0.35 |
ENSMUST00000042779.3
|
zinc finger and BTB domain containing 1 |
|
| chr7_+_27653906 Show fit | 0.34 |
ENSMUST00000008088.7
|
tetratricopeptide repeat domain 9B |
|
| chr8_-_92355764 Show fit | 0.34 |
ENSMUST00000180102.1
ENSMUST00000179421.1 ENSMUST00000179222.1 ENSMUST00000179029.1 |
RIKEN cDNA 4933436C20 gene |
|
| chr14_-_79481268 Show fit | 0.32 |
ENSMUST00000022601.5
|
WW domain binding protein 4 |
Network of associatons between targets according to the STRING database.
First level regulatory network of Egr4
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 0.8 | GO:2000327 | regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327) |
| 0.0 | 0.5 | GO:0006783 | heme biosynthetic process(GO:0006783) |
| 0.1 | 0.3 | GO:2001076 | negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302) regulation of metanephric ureteric bud development(GO:2001074) positive regulation of metanephric ureteric bud development(GO:2001076) |
| 0.1 | 0.3 | GO:0002572 | pro-T cell differentiation(GO:0002572) |
| 0.1 | 0.3 | GO:0008291 | acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619) |
| 0.1 | 0.3 | GO:2000623 | regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623) |
| 0.0 | 0.3 | GO:0045292 | mRNA cis splicing, via spliceosome(GO:0045292) |
| 0.0 | 0.3 | GO:0050860 | negative regulation of T cell receptor signaling pathway(GO:0050860) |
| 0.1 | 0.2 | GO:0021852 | pyramidal neuron migration(GO:0021852) |
| 0.1 | 0.2 | GO:0002270 | plasmacytoid dendritic cell activation(GO:0002270) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.3 | GO:0043083 | synaptic cleft(GO:0043083) |
| 0.0 | 0.3 | GO:1990124 | messenger ribonucleoprotein complex(GO:1990124) |
| 0.0 | 0.2 | GO:0019907 | cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907) |
| 0.0 | 0.2 | GO:0072687 | meiotic spindle(GO:0072687) |
| 0.0 | 0.2 | GO:0042622 | photoreceptor outer segment membrane(GO:0042622) |
| 0.0 | 0.1 | GO:0031523 | Myb complex(GO:0031523) |
| 0.0 | 0.1 | GO:0089701 | U2AF(GO:0089701) |
| 0.0 | 0.1 | GO:0045298 | tubulin complex(GO:0045298) |
| 0.0 | 0.1 | GO:1990909 | Wnt signalosome(GO:1990909) |
| 0.0 | 0.0 | GO:0002111 | BRCA2-BRAF35 complex(GO:0002111) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.8 | GO:0032183 | SUMO binding(GO:0032183) |
| 0.1 | 0.3 | GO:0004104 | cholinesterase activity(GO:0004104) |
| 0.1 | 0.3 | GO:0098519 | nucleotide phosphatase activity, acting on free nucleotides(GO:0098519) |
| 0.0 | 0.3 | GO:0044729 | hemi-methylated DNA-binding(GO:0044729) |
| 0.0 | 0.3 | GO:0070530 | K63-linked polyubiquitin binding(GO:0070530) |
| 0.0 | 0.3 | GO:0070064 | proline-rich region binding(GO:0070064) |
| 0.0 | 0.3 | GO:0008143 | poly(A) binding(GO:0008143) |
| 0.1 | 0.2 | GO:0000402 | open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402) |
| 0.0 | 0.1 | GO:0004703 | G-protein coupled receptor kinase activity(GO:0004703) |
| 0.0 | 0.1 | GO:0016907 | G-protein coupled acetylcholine receptor activity(GO:0016907) |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.3 | REACTOME SYNTHESIS OF PC | Genes involved in Synthesis of PC |
| 0.0 | 0.2 | REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION | Genes involved in Apoptosis induced DNA fragmentation |